CN108982894A - A kind of thermostatic type sample introduction needle for level detection - Google Patents
A kind of thermostatic type sample introduction needle for level detection Download PDFInfo
- Publication number
- CN108982894A CN108982894A CN201811099991.8A CN201811099991A CN108982894A CN 108982894 A CN108982894 A CN 108982894A CN 201811099991 A CN201811099991 A CN 201811099991A CN 108982894 A CN108982894 A CN 108982894A
- Authority
- CN
- China
- Prior art keywords
- sample introduction
- introduction needle
- heater
- heating muff
- level detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 45
- 238000010438 heat treatment Methods 0.000 claims abstract description 41
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 17
- 239000000203 mixture Substances 0.000 claims abstract description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 8
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 8
- -1 polytetrafluoroethylene Polymers 0.000 claims description 4
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 17
- 239000000284 extract Substances 0.000 abstract description 3
- 238000009510 drug design Methods 0.000 abstract description 2
- 238000002347 injection Methods 0.000 abstract description 2
- 239000007924 injection Substances 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 238000010876 biochemical test Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical compound FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N2035/1025—Fluid level sensing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The present invention relates to a kind of thermostatic type sample introduction needles for level detection, belong to medical instrument, technology of instrument and meter field.Thermostatic type sample introduction needle is by heater, peristaltic pump, heating muff and sample introduction needle composition, after water reaches target temperature in heater, peristaltic pump extracts water by pipeline out from heater, and it is injected into heating muff by hose from heating muff bottom end, since sample introduction needle is located in heating muff, under the action of the hot water of injection heating casing, sample in sample introduction needle, reagent can be maintained at temperature constant state, hot water is flowed back into heater by pipeline, due to heater, peristaltic pump, it is connected between sample introduction needle with hose, be conducive to sample introduction needle to carry out extracting reagent and level detection in different location.The present invention has rational design, structure is simple, using recirculated water in sample introduction needle outer wall sleeve constant flow, can guarantee that reagent or sample can be cooled uniformly in this way, avoid level detection signal disturbed.
Description
Technical field
The present invention relates to a kind of thermostatic type sample introduction needles for level detection, belong to medical instrument, instrument field.
Background technique
In bioengineering field, automation equipment generally will use the function of automatic sampling, need to use sample introduction
Needle carries out sample suction operation.Since the amount of reagent that sample introduction needle is drawn is small, sample introduction needle stitch internal diameter is tiny, it is easy to draw sample
This when, collides with reagent bottle, heparin tube and is damaged, this just needs sample introduction needle can be when touching the surface of reagent, sample just
It can detect liquid level, and control moving component and stop working, to realize the function of anticollision.Meanwhile many biochemical tests with
Sample introduction needle draws reagent or when sample, needs within a short period of time to heat reagent or sample, and get reagent or
Sample, but in traditional technology, in sample introduction needle reagent or sample heat, be usually coated with one layer of electricity in sample introduction needle outer wall
Resistance silk or heating film, this heating method cannot quickly and uniformly heat reagent, simultaneously because the electric current in resistance wire can be right
Sample introduction needle level detection result impacts.
Summary of the invention
In view of the above problems, the present invention provides a kind of thermostatic type sample introduction needles for level detection, for reality
Existing above-mentioned purpose, its technical solution is that:
A kind of thermostatic type sample introduction needle for level detection, thermostatic type sample introduction needle by heater, peristaltic pump, heating muff and
Sample introduction needle composition, heater are a closed container, and temperature sensor is provided in heater, is equipped with water supply connector above heater
And water outlet connector, heating muff be in hollow cylinder shape, heating muff upper end be equipped with water outlet connector, heating muff lower end be equipped with into
Water swivel, heater upper water-out connector are connected in peristaltic pump water supply connector by pipeline, and the water outlet connector of peristaltic pump passes through pipe
Road is connected in the water supply connector of heating muff, and the water outlet connector of heating muff is connected to the water supply connector of heater by pipeline
On, it is coated with polytetrafluoroethylene (PTFE) shielded layer in sample introduction needle outside wall surface, signal shielding line is provided in sample introduction needle, sample introduction needle, which is sleeved on, to be added
In thermal sleeve, peristaltic pump and temperature sensor are linked on controller by conducting wire respectively, and signal shielding line is linked into level detection
On controller.
Due to using above technical scheme, the present invention is provided with temperature sensor in heater, uses to heater
Water is heated in built-in heating or the mode heater of external heating, and controls temperature, heating by temperature sensor
After water reaches target temperature in device, peristaltic pump extracts water by pipeline out from heater, and passes through hose from heating muff bottom
End is injected into heating muff, since sample introduction needle is located in heating muff, under the action of the hot water of injection heating casing, and sample introduction
Sample, reagent in needle can guarantee to greatest extent the reaction condition of reagent, sample, heating muffs waited to fill under temperature constant state
After full water, hot water is flowed back into heater by pipeline, due to being connected between heater, peristaltic pump, sample introduction needle with hose, favorably
It carries out extracting reagent and level detection in different location in sample introduction needle.
The present invention has rational design, structure is simple, using recirculated water in sample introduction needle outer wall sleeve constant flow, in this way can be with
Guarantee that reagent or sample can be cooled uniformly, meanwhile, sample introduction needle appearance is coated with by polytetrafluoroethylene (PTFE), water will not and sample introduction needle
Conducting, avoids level detection signal interference., sample introduction needle outer wall do not have to coating resistance wire or heating film, avoids to level detection
Signal generates interference.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of thermostatic type sample introduction needle of the present invention.
Specific embodiment
Present invention is further described in detail in the following with reference to the drawings and specific embodiments, sees attached drawing.
A kind of thermostatic type sample introduction needle for level detection, thermostatic type sample introduction needle is by heater 1, peristaltic pump 3, heating muff
6 and sample introduction needle 5 form, heater 1 is a closed container, is provided with temperature sensor 2 in heater, is equipped with above heater 1
Water supply connector and water outlet connector, heating muff 6 are in hollow cylinder shape, and 6 upper end of heating muff is equipped with water outlet connector, heating muff
6 lower ends are equipped with water supply connector, and 1 upper water-out connector of heater is connected in 3 water supply connector of peristaltic pump by pipeline, peristaltic pump 3
Water outlet connector is connected in the water supply connector of heating muff 6 by pipeline, and the water outlet connector of heating muff 6 is connected to by pipeline
In the water supply connector of heater 1, it is coated with polytetrafluoroethylene (PTFE) shielded layer in 5 outside wall surface of sample introduction needle, is provided with signal screen in sample introduction needle 5
Line 7 is covered, sample introduction needle 5 is sleeved in heating muff 6, and peristaltic pump 3 and temperature sensor 2 are linked on controller 4 by conducting wire respectively,
Signal shielding line is linked on level detection controller.
Heater 1 can use built-in heating or external heating method, when water reaches target temperature in heater 1
Afterwards, peristaltic pump 3 extracts water out from heater 1, and injects from 6 bottom end of heating muff, and hot water can be with reagent, sample in sample introduction needle
Heat exchange is carried out, after heating muff 6 is full of hot water, hot water flows back into heater 1 from 6 top of heating muff.
As it can be seen that the present invention suitable for bioengineering field, need to carry out level detection with sample introduction needle, to sample or
The case where reagent is heated.The present invention builds simple and convenient the of less demanding of sample introduction needle.In the cost of entire method
On, due to not needing to heat in sample introduction needle again, the function of temperature feedback reduces the processing technology of sample introduction needle complexity.Meanwhile
Due to all having plated a strata tetrafluoroethene in sample introduction needle device sample introduction conduit and shielding shell inside and outside, sample introduction needle is advantageously reduced
Hang liquid phenomenon.
Claims (2)
1. a kind of thermostatic type sample introduction needle for level detection, it is characterised in that: thermostatic type sample introduction needle is by heater (1), wriggling
(3), heating muff (6) and sample introduction needle (5) composition are pumped, heater (1) is a closed container, is provided with temperature in heater (1)
Sensor (2), heater (1) top are equipped with water supply connector and water outlet connector, and heating muff (6) is in hollow cylinder shape, heating
Sleeve (6) upper end is equipped with water outlet connector, and heating muff (6) lower end is equipped with water supply connector, and heater (1) upper water-out connector passes through pipe
Road is connected in peristaltic pump (3) water supply connector, the water outlet connector of peristaltic pump (3) by pipeline be connected to heating muff (6) into
On water swivel, the water outlet connector of heating muff (6) is connected in the water supply connector of heater (1) by pipeline, and sample introduction needle (5) is outside
It is coated with polytetrafluoroethylene (PTFE) shielded layer on wall surface, is provided in sample introduction needle (5) signal shielding line (7), sample introduction needle (5) is sleeved on heating
In casing (6), peristaltic pump (3) and temperature sensor (2) are linked on controller (4) by conducting wire respectively.
2. a kind of thermostatic type sample introduction needle for level detection as described in claim 1, it is characterised in that: the pipeline is
Hose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811099991.8A CN108982894A (en) | 2018-09-20 | 2018-09-20 | A kind of thermostatic type sample introduction needle for level detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811099991.8A CN108982894A (en) | 2018-09-20 | 2018-09-20 | A kind of thermostatic type sample introduction needle for level detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108982894A true CN108982894A (en) | 2018-12-11 |
Family
ID=64546485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811099991.8A Pending CN108982894A (en) | 2018-09-20 | 2018-09-20 | A kind of thermostatic type sample introduction needle for level detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108982894A (en) |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02218949A (en) * | 1989-02-20 | 1990-08-31 | Rigaku Corp | Apparatus for heating and cooling thermally analyzing sample |
| CN1528247A (en) * | 2003-10-13 | 2004-09-15 | 珠海市和佳医疗设备有限公司 | Tumour-inserting thermo therapy instrument |
| CN2715765Y (en) * | 2002-12-30 | 2005-08-10 | 中国科学院理化技术研究所 | Thermotherapy device for extracorporeal circulation |
| CN202994807U (en) * | 2012-12-25 | 2013-06-12 | 深圳雷杜生命科学股份有限公司 | Sampling needle |
| CN203825509U (en) * | 2014-04-25 | 2014-09-10 | 浙江环茂自控科技有限公司 | Constant-temperature sample introduction reaction device |
| WO2016044146A2 (en) * | 2014-09-18 | 2016-03-24 | Deka Products Limited Partnership | Apparatus and method for infusing fluid through a tube by appropriately heating the tube |
| CN105499231A (en) * | 2016-02-23 | 2016-04-20 | 广州埃克森生物科技有限公司 | Biochemical instrument liquid path system and method |
| CN205413827U (en) * | 2016-02-23 | 2016-08-03 | 广州埃克森生物科技有限公司 | Biochemical analyzer liquid way system |
| CN207008435U (en) * | 2017-08-16 | 2018-02-13 | 北京普利生仪器有限公司 | A kind of reagent pin and medical automatic detection instrument |
| CN209311506U (en) * | 2018-09-20 | 2019-08-27 | 武汉纺织大学 | A kind of thermostatic type sample introduction needle for level detection |
-
2018
- 2018-09-20 CN CN201811099991.8A patent/CN108982894A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02218949A (en) * | 1989-02-20 | 1990-08-31 | Rigaku Corp | Apparatus for heating and cooling thermally analyzing sample |
| CN2715765Y (en) * | 2002-12-30 | 2005-08-10 | 中国科学院理化技术研究所 | Thermotherapy device for extracorporeal circulation |
| CN1528247A (en) * | 2003-10-13 | 2004-09-15 | 珠海市和佳医疗设备有限公司 | Tumour-inserting thermo therapy instrument |
| CN202994807U (en) * | 2012-12-25 | 2013-06-12 | 深圳雷杜生命科学股份有限公司 | Sampling needle |
| CN203825509U (en) * | 2014-04-25 | 2014-09-10 | 浙江环茂自控科技有限公司 | Constant-temperature sample introduction reaction device |
| WO2016044146A2 (en) * | 2014-09-18 | 2016-03-24 | Deka Products Limited Partnership | Apparatus and method for infusing fluid through a tube by appropriately heating the tube |
| CN105499231A (en) * | 2016-02-23 | 2016-04-20 | 广州埃克森生物科技有限公司 | Biochemical instrument liquid path system and method |
| CN205413827U (en) * | 2016-02-23 | 2016-08-03 | 广州埃克森生物科技有限公司 | Biochemical analyzer liquid way system |
| CN207008435U (en) * | 2017-08-16 | 2018-02-13 | 北京普利生仪器有限公司 | A kind of reagent pin and medical automatic detection instrument |
| CN209311506U (en) * | 2018-09-20 | 2019-08-27 | 武汉纺织大学 | A kind of thermostatic type sample introduction needle for level detection |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181211 |
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| WD01 | Invention patent application deemed withdrawn after publication |