CN109431895A - A kind of scalp care compositions of Anti-hair loss and its preparation method and application - Google Patents
A kind of scalp care compositions of Anti-hair loss and its preparation method and application Download PDFInfo
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- CN109431895A CN109431895A CN201811407430.XA CN201811407430A CN109431895A CN 109431895 A CN109431895 A CN 109431895A CN 201811407430 A CN201811407430 A CN 201811407430A CN 109431895 A CN109431895 A CN 109431895A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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Abstract
The invention discloses scalp care compositions of a kind of Anti-hair loss and its preparation method and application.The scalp care compositions of the Anti-hair loss include dihydrosphingosine, creatine, phytosterols oletate and houttuynia extract.The scalp care compositions of Anti-hair loss of the invention contain dihydrosphingosine, creatine, phytosterols oletate and houttuynia extract, dihydrosphingosine energy hair follicle stimulating forms hair fiber, the activated reinforced skin of creatine energy, phytosterols oletate can promote scalp metabolism to repair, houttuynia extract can have excellent antiallergic antibacterial action, by having effects that collaboration between each component, the effect of each component can be made to perform to maximum, so that scalp is more healthy, conducive to natural on-off cycles of hair growth, achieve the effect that prevent hair loss, it can be widely applied to prepare and various wash hair products.
Description
Technical field
The present invention relates to daily use chemicals technical fields, more particularly, to the scalp care compositions and its system of a kind of Anti-hair loss
Preparation Method and application.
Background technique
With the promotion of people's living standard, the requirement to daily necessities such as daily chemical products is also higher and higher, on the market often
That sees only focuses on the use demand for being no longer satisfied present consumer of traditional hair care product of maintenance hair.Now
Consumer increasingly focuses on the nursing of scalp, appreciates scalp health also slowly conducive to hair healthy, scalp health is not only
Help to improve moist degree, glossiness, smoothness and the pliability of hair, it is most important that play the effect of Anti-hair loss.Head
Hair is an important component of human skin tissue.Hair generates in hair follicle, the nourishment and metabolic condition of hair follicle
Directly determine the health condition of hair, and hair follicle and scalp are closely bound up, therefore it is very important for scalp care.
Alopecia in order to prevent can also be by operative treatment or the method for drug therapy other than healthy lifestyles, but expense
Higher-security is poor, it is also possible to again resulting in depilation phenomenon if nursing improper be stimulated, has potential risks.
Therefore it provides a kind of hair products of washing with Anti-hair loss effect have very important meaning for the alopecia for solving people
Justice.It is also disclosed relevant Anti-hair loss, medicinal combination for growing hair object, such as patent CN106620616A in the prior art and discloses one
The pharmaceutical composition that kind is formed with the fleece-flower root, ginger, Cortex Phellodendri, rhizome of chuanxiong, the root bark of white mulberry, fructus viticis, ganoderma lucidum, Selaginella tamariscina, safflower and cordate houttuynia
Object, has alopecia certain inhibitory effect, but and the scalp problems such as unresolved hair follicle reparation, cannot fundamentally solve to prevent
The problem of alopecia.
Therefore it provides it is a kind of by improving scalp health, promote scalp hair follicles reparation and natural on-off cycles of hair growth to reach pre- anticreep
The scalp care compositions of hair, which prevent hair loss profound level, to have very important significance.
Summary of the invention
Cannot go deep into scalp hair follicles the technical problem to be solved by the present invention is to overcome existing Anti-hair loss composition improves alopecia
The defect and deficiency of problem, provide a kind of scalp care compositions of Anti-hair loss, which passes through dihydrosphingosine, flesh
The synergistic effect of acid, phytosterols oletate, houttuynia extract, repairing effect go directly hair follicle, and deep layer repairs scalp, thus real
Existing natural on-off cycles of hair growth, the hair care effect prevented hair loss.
Another object of the present invention is to provide a kind of preparation methods of scalp care compositions.
Another object of the present invention is to provide a kind of scalp care compositions in the application washed in hair products.
Another object of the present invention is to provide one kind to wash hair products.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of scalp care compositions of Anti-hair loss, the scalp composition include dihydrosphingosine, creatine, phytosterol
Oleate and houttuynia extract.
Scalp care compositions kind of the invention contains dihydrosphingosine, creatine, phytosterols oletate and cordate houttuynia and mentions
Object is taken,
Wherein dihydrosphingosine energy hair follicle stimulating forms hair fiber, promotes scalp health, facilitates natural on-off cycles of hair growth anticreep
Hair;
The activated reinforced skin of creatine energy, facilitates scalp health, is the multifunction activity object of hair, plays the function of Anti-hair loss
Effect;
Phytosterols oletate has an excellent moisturizing repair, effectively resistance external irritant, can promote scalp new old generation
It thanks and accelerates scalp injury reparation, so that scalp health, facilitates Anti-hair loss;
Houttuynia extract is the herb extract of Saururaceae heartleaf houttuynia platymiscium heartleaf houttuynia, mainly contains volatile oil, flavones
The ingredients such as class, alkaloid, organic acid and sterols, the houttuynia extract take water as a solvent, after heating and refluxing extraction, concentration
Obtaining solid powder is extract, also commercially available.Houttuynia extract can make scalp telangiectasis, there is antiallergic antibacterial
Effect is conducive to natural on-off cycles of hair growth, prevents hair loss so that scalp is more healthy.
Anti-hair loss composition and the prior art of the invention adjusts reduction head by endocrine controls such as inrigorating qi and promoting blood circulations
The Anti-hair loss mechanism of the anti-hair loss products of falling out is entirely different, and the present invention passes through multiple reparation scalp skin and scalp hair follicles machine
Reason combines, and by fundamentally protecting scalp health and moisturizing reparation, promotes natural on-off cycles of hair growth to achieve the purpose that improve alopecia,
Improvement is significant and lasting.
As a preferred embodiment, the mass percent of the composition each component are as follows: dihydrosphingosine 0.005~
3.0%, creatine 0.01~5.0%, phytosterols oletate 0.1~10.0%, houttuynia extract 0.5~10.0%, surplus
For pure water.Each component content interacts within this range can play comparatively ideal Anti-hair loss effect.
Preferably, the mass percent of the composition each component are as follows: dihydrosphingosine 0.2~1.0%, creatine 0.1~
2.0%, phytosterols oletate 1.0~5.0%, houttuynia extract 3.0~7.0%, surplus is pure water.Such as dihydro sheath
Ammonia alcohol can be 0.2%, 0.6%, 1.0%, 2.0%, 3.0%, and creatine can be 0.1%, 1.0%, 2.0%, phytosterol
Oleate can be 1.0%, 3.5%, 5.0%, and houttuynia extract can be 0.5%, 3.0%, 5.5%, 7.0%.
It is highly preferred that the mass percent of the composition each component are as follows: dihydrosphingosine 0.6%, creatine 1.0% are planted
Object oleate ester 3.5%, houttuynia extract 5.5%, surplus are pure water.
Further, the composition of the application is by dihydrosphingosine, creatine, phytosterols oletate and houttuynia extract
With specific content joint compatible use, the synergistic effect of the different nursing care mechanism of wherein each component is sufficiently combined.In this hair
The scalp care effect of any component can not all lack in bright scalp care compositions, have the function of certain phase
Interaction and Compatibility Law, when the special ratios limited using the application are carried out each component in the application composition reasonably
When compatibility, the synergistic effect between each component can be reinforced, it is made to become more significant to the improvement result of alopecia and scalp, it can
Play the role of nourishing and repairs scalp and promotion natural on-off cycles of hair growth.
The present invention also provides a kind of preparation methods of the scalp care compositions of above-mentioned Anti-hair loss, include the following steps:
S1. dihydrosphingosine, phytosterols oletate are mixed and heated to 60~85 DEG C after completely dissolution, added pure
Water forms uniform system;
S2. above-mentioned uniform system is cooled to 50 DEG C hereinafter, houttuynia extract and equal with dissolved in purified water in advance is added
Even creatine is sufficiently mixed to obtain uniform solution, that is, the scalp care compositions is prepared.Dihydrosphingosine is directly in water
In solubility it is lower, add pure water after completely dissolution with phytosterols oletate, the two mixes more evenly, then cools down
Houttuynia extract and creatine is added, can quickly and easily prepare the composition in this way.
A kind of above-mentioned scalp care compositions the application washed in hair products also within protection scope of the present invention.This
The scalp care compositions of invention make scalp more healthy by scalp care, to reach prevention epilation and reduce head
The effect of falling out can be directly sprayed on scalp on a small quantity, the Anti-hair loss nutrients of scalp care can also directly be added
It is used in washing hair products, it is daily to wash hair care.
One kind washing hair products, and described wash contains above-mentioned scalp care compositions in hair products.It is described to wash hair products
It can be elution class hair product or resident class hair product, including shampoo, hair cream, hair conditioner, hair film, hair jelly, transdermal
Conditioning liquid, hair are spraying or embellish hair essence is oily.
Preferably, the scalp care compositions, which account for, washes the 1.0~50.0% of hair products gross mass.
It is highly preferred that the scalp care compositions, which account for, washes the 35.0% of hair products gross mass.
Compared with prior art, the beneficial effects of the present invention are:
The present invention provides the hair products of washing of a kind of scalp care compositions of Anti-hair loss and its preparation, of the invention is anti-
The scalp care compositions of alopecia contain dihydrosphingosine, creatine, phytosterols oletate and houttuynia extract, dihydro sheath ammonia
Alcohol energy hair follicle stimulating forms hair fiber, the activated reinforced skin of creatine energy, and phytosterols oletate can promote scalp metabolism to repair
Multiple, houttuynia extract can have excellent antiallergic antibacterial action, by having effects that collaboration between each component, can make each group
The effect divided performs to maximum, so that scalp is more healthy, is conducive to natural on-off cycles of hair growth, achievees the effect that prevent hair loss, can answer extensively
It is used to prepare and various washes hair products.
Specific embodiment
The present invention is further illustrated With reference to embodiment, but embodiment the present invention is not done it is any
The restriction of form.Unless otherwise indicated, source chemicals used in the embodiment of the present invention are the source chemicals routinely bought.
Embodiment 1~17
A kind of scalp care compositions of Anti-hair loss, including dihydrosphingosine, creatine, phytosterols oletate and cordate houttuynia
Wherein each component content is as shown in table 1 whether there is or not specific ingredient and corresponding content for extract, and surplus is water.
Table 1
Serial number | Dihydrosphingosine/% | Creatine/% | Phytosterols oletate/% | Houttuynia extract/% |
Embodiment 1 | 0.6 | 1.0 | 3.5 | 5.5 |
Embodiment 2 | 0.2 | 0.1 | 1.0 | 3.0 |
Embodiment 3 | 1.0 | 1.0 | 3.5 | 5.5 |
Embodiment 4 | 0.6 | 0.1 | 3.5 | 3.0 |
Embodiment 5 | 0.6 | 2.0 | 3.5 | 5.5 |
Embodiment 6 | 1.0 | 1.0 | 1.0 | 5.5 |
Embodiment 7 | 0.2 | 2.0 | 5.0 | 3.0 |
Embodiment 8 | 0.6 | 1.0 | 3.5 | 3.0 |
Embodiment 9 | 1.0 | 2.0 | 5.0 | 7.0 |
Embodiment 10 | 0.005 | 0.01 | 0.1 | 0.5 |
Embodiment 11 | 3.0 | 5.0 | 10.0 | 10.0 |
Embodiment 12 | 0.6 | 0.01 | 3.5 | 5.5 |
Embodiment 13 | 1.0 | 5.0 | 5.0 | 7.0 |
Embodiment 14 | 3.0 | 5.0 | 0.1 | 10.0 |
Embodiment 15 | 0.6 | 3.5 | 10.0 | 5.5 |
Embodiment 16 | 0.6 | 1.0 | 3.5 | 0.5 |
Embodiment 17 | 0.2 | 0.1 | 5.0 | 10.0 |
Embodiment 18
A kind of shampoo, the scalp care compositions including embodiment 1, remaining group are divided into other compositions needed for shampoo,
It is respectively as follows: water, laureth sulfuric ester ammonium, laurel alcohol sulfuric ester ammonium, Cocoamidopropyl betaine, polydimethylsiloxanes
Alkane, coconut oleoyl amine MEA, glycol distearate, guar hydroxypropyltrimonium chloride, sodium chloride, EDETATE SODIUM, anti-corrosion
Agent, citric acid, essence.Used shampoo raw material, reagent etc., unless otherwise specified, being can be from the business such as conventional market
The raw materials and reagents that approach obtains,
The concrete composition of shampoo is as follows:
Operating method: in water-bath, constant temperature after water is heated to 80~85 DEG C, it is water-dispersible good in advance to be then added
Then guar hydroxypropyltrimonium chloride, EDETATE SODIUM, citric acid add laureth sulfuric ester ammonium, laruyl alcohol
Sulfuric ester ammonium, Cocoamidopropyl betaine add coconut oleoyl amine MEA, ethylene glycol distearyl acid after it is completely dissolved
Ester, constant temperature after twenty minutes, cool to 45 DEG C hereinafter, adding remaining dimethyl silicone polymer, sodium chloride, preservative and perfume (or spice)
Essence is eventually adding scalp care compositions, continues stirring 15 minutes.
Embodiment 19
A kind of shampoo of the scalp care compositions of Anti-hair loss, the difference with embodiment 18 are as follows: scalp care compositions
Content is 1.0%.
Embodiment 20
A kind of shampoo of the scalp care compositions of Anti-hair loss, the difference with embodiment 18 are as follows: scalp care compositions
Content is 20.0%.
Embodiment 21
A kind of shampoo of the scalp care compositions of Anti-hair loss, the difference with embodiment 18 are as follows: scalp care compositions
Content is 40.0%.
Embodiment 22
A kind of shampoo of the scalp care compositions of Anti-hair loss, the difference with embodiment 18 are as follows: scalp care compositions
Content is 50.0%.
Comparative example 1~7
A kind of scalp care compositions of Anti-hair loss, wherein the mass percent of each component is shown in Table 2.
Table 2
Serial number | Dihydrosphingosine/% | Creatine/% | Phytosterols oletate/% | Houttuynia extract/% |
Comparative example 1 | 0 | 0 | 0 | 0 |
Comparative example 2 | 0 | 1.0 | 3.5 | 5.5 |
Comparative example 3 | 0.6 | 0.0 | 3.5 | 5.5 |
Comparative example 4 | 0.6 | 1.0 | 0.0 | 5.5 |
Comparative example 5 | 0.6 | 1.0 | 3.5 | 0.0 |
Comparative example 6 | 0 | 0 | 3.5 | 5.5 |
Comparative example 7 | 0 | 1.0 | 0 | 5.5 |
Comparative example 8
A kind of shampoo of the scalp care compositions of Anti-hair loss, the difference with embodiment 18 are as follows: without head of the invention
Skin care composition.
As a result it detects
The scalp care compositions and shampoo provide embodiment and comparative example carry out Anti-hair loss and scalp health performance
Test.Specific anticreep effect, scalp moisturization effect and hair follicle repairing effect are as follows:
(1) test method
By test volunteer, (4 people of each formula the age 25~60 years old, have dispersibility to the present invention, non-health relevant
Alopecia and thin and lifeless hair), the sample of Examples 1 to 22 and comparative example 1~8 is tried out respectively, is used for scalp weekly
Twice, totally 12 weeks, record used anticreep effect, scalp moisturization effect and the hair follicle repairing effect after 12 weeks, tracking and testing, examination
The improvement situation of each volunteer.Test effect scores by evaluation method, and final result takes grade average.
(2) evaluation method
Testing evaluation standard: being divided into 1,2,3,4,5 five grade, wherein 1 is that effect is not improved, 2 be effect
Fruit improves unobvious, and 3 be that effect slightly improves, 4 be it is effect improved good, 5 be effect improved obvious, and with 0.1 point for interval
Assessment improves situation, and the grade average of comprehensive every group of 4 people, calculated result are shown in Table 3 testing evaluation results after finally trying out 12 weeks.
Anticreep effect evaluation method is the hair loss situation for observing daily combing hair, and hair loss multilist shows that effect is bad, hair loss
Indicate that effect is good less or almost without hair loss.
Scalp moisturization effect evaluation method is the comfortable moist degree of sensory experience's hair, and the tight expression effect of dry scalp is not
Good, scalp is comfortable, and to moisten non-stimulated expression effect good.
Hair follicle repairing effect evaluation method is that the firmness of hair observation scalp root of hair is gently pullled with hand, and hair is easy to draw
Tearing off indicates that hair follicle repairing effect is bad, and it is good that hair is not easy to pull expression hair follicle repairing effect.
Table 3
The present invention evaluates anticreep effect using the overall feeling situation after sample by tracking and testing volunteer, scalp is protected
Wet effect and hair follicle repairing effect.As shown in Table 3, the test result of embodiment and comparative example shows between 1 each component of embodiment
Synergistic effect reaches the best perfect condition of Anti-hair loss effect, the improvement of hair loss situation is most ideal, most so that scalp is more healthy
The effect of Anti-hair loss is played eventually.As shown in Table 3, the Anti-hair loss nutrients of the scalp care in embodiment 18 is in shampoo
When mass fraction is 35.0%, so that scalp is more healthy, the improvement of hair loss situation is most ideal, has finally played the effect of Anti-hair loss
Fruit.The Anti-hair loss nutrients of scalp care of the invention is applied to wash in hair products, is enabled and is washed hair products and reach one
The effect of kind Anti-hair loss.
Obviously, the above embodiment of the present invention be only to clearly illustrate example of the present invention, and not be pair
The restriction of embodiments of the present invention.For those of ordinary skill in the art, may be used also on the basis of the above description
To make other variations or changes in different ways.There is no necessity and possibility to exhaust all the enbodiments.It is all this
Made any modifications, equivalent replacements, and improvements etc., should be included in the claims in the present invention within the spirit and principle of invention
Protection scope within.
Claims (9)
1. a kind of scalp care compositions of Anti-hair loss, which is characterized in that the scalp composition includes dihydrosphingosine, flesh
Acid, phytosterols oletate and houttuynia extract.
2. scalp care compositions as described in claim 1, which is characterized in that the mass percent of the composition each component
Are as follows: dihydrosphingosine 0.005~3.0%, creatine 0.01~5.0%, phytosterols oletate 0.1~10.0%, houttuynia extract
0.5~10.0%, surplus is pure water.
3. scalp care compositions as claimed in claim 2, which is characterized in that the mass percent of the composition each component
Are as follows: dihydrosphingosine 0.2~1.0%, creatine 0.1~2.0%, phytosterols oletate 1.0~5.0%, houttuynia extract 3.0
~7.0%, surplus is pure water.
4. scalp care compositions as claimed in claim 3, which is characterized in that the mass percent of the composition each component
Are as follows: dihydrosphingosine 0.6%, creatine 1.0%, phytosterols oletate 3.5%, houttuynia extract 5.5%, surplus are pure water.
5. a kind of preparation method of scalp care compositions described in claim 1 ~ 4 any one, which is characterized in that including as follows
Step:
S1. dihydrosphingosine, phytosterols oletate and pure water are mixed and heated to 60~85 DEG C, form uniform system;
S2. above-mentioned uniform system is cooled to 50 DEG C hereinafter, houttuynia extract and uniform with dissolved in purified water in advance is added
Creatine is sufficiently mixed to obtain uniform solution, that is, the scalp care compositions is prepared.
6. scalp care compositions described in a kind of claim 1 ~ 4 any one are in the application washed in hair products.
7. one kind washes hair products, which is characterized in that described to wash in hair products containing any one of claim 1 ~ 4 scalp
Care composition.
8. washing hair products as claimed in claim 7, which is characterized in that the scalp care compositions, which account for, washes the total matter of hair products
The 1.0~50.0% of amount.
9. washing hair products as claimed in claim 8, which is characterized in that the scalp care compositions, which account for, washes the total matter of hair products
The 35.0% of amount.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110314105A (en) * | 2019-06-20 | 2019-10-11 | 上海绿瑞生物科技有限公司 | A kind of hair-loss preventing and hair-restoring class Essence and preparation method thereof |
CN113384509A (en) * | 2021-06-22 | 2021-09-14 | 科丝美诗(中国)化妆品有限公司 | Composition for preventing hair loss, fixing hair, removing dandruff and controlling oil and application thereof |
CN114099362A (en) * | 2021-09-03 | 2022-03-01 | 太和康美(北京)中医研究院有限公司 | Shampoo containing phytosterol and phytosterol ester and preparation method thereof |
-
2018
- 2018-11-23 CN CN201811407430.XA patent/CN109431895A/en not_active Withdrawn
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110314105A (en) * | 2019-06-20 | 2019-10-11 | 上海绿瑞生物科技有限公司 | A kind of hair-loss preventing and hair-restoring class Essence and preparation method thereof |
CN113384509A (en) * | 2021-06-22 | 2021-09-14 | 科丝美诗(中国)化妆品有限公司 | Composition for preventing hair loss, fixing hair, removing dandruff and controlling oil and application thereof |
CN114099362A (en) * | 2021-09-03 | 2022-03-01 | 太和康美(北京)中医研究院有限公司 | Shampoo containing phytosterol and phytosterol ester and preparation method thereof |
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Application publication date: 20190308 |