CN109394642A

CN109394642A - A kind of anti-inflammatory skin care item and preparation method thereof of releiving

Info

Publication number: CN109394642A
Application number: CN201811467578.2A
Authority: CN
Inventors: 王健; 何灿平; 何灿洋; 侯雷; 竺亚斌
Original assignee: Hangzhou Engel Biological Medical Technology Co Ltd
Current assignee: Hangzhou Engel Biological Medical Technology Co Ltd
Priority date: 2018-12-03
Filing date: 2018-12-03
Publication date: 2019-03-01

Abstract

The invention discloses a kind of anti-inflammatory skin care item and preparation method thereof of releiving, raw material including following parts by weight: cetostearyl alcohol, cetearyl glucoside, saualane, jojoba seed oil, dimethyl silicone polymer, Butyrospermum parkii fruit rouge, lecithin, Cer NP, dipropylene glycol, sphingolipid, sucrose distearate, cholesterol, vaseline, mineral oil, water, panthenol, glycerol, glycine betaine, 1, 3-propanediol, allantoin, xanthan gum, acrylic acid, asiaticosid, Phosphoric acid monohexadecyl ester potassium, methyl hydroxybenzoate, dipotassium glycyrrhizinate, Radix Ophiopogonis root extract, Phenoxyethanol, Sensiva SC50, tocopherol acetate, tocopherol, bisabolol and tromethamine.This product raw material sources are extensive, and preparation process is simple, and by being used cooperatively various raw materials, the finished product of preparation has good anti-inflammatory effect of releiving, and can satisfy the use demand of people, have wide prospect of the application.

Description

A kind of anti-inflammatory skin care item and preparation method thereof of releiving

Technical field

The present invention relates to skin care field, specifically a kind of anti-inflammatory skin care item of releiving.

Background technique

With the development of economy, increasingly attention of the abundant and people of material life for itself appearance instrument, it is more next More people have used cosmetics.Cosmetics refer to smearing, sprinkling or other similar method, intersperse among appointing for human body surface What position, such as skin, hair, refer to toenail, lips and teeth, to reach cleaning, maintenance, beauty, modification and change appearance, or amendment Human scent, chemical industrial product or fine chemical product for the purpose of maintaining a good state.

Skin care item are exactly a kind of common cosmetics, and skin care item protect the skin-protection product of skin, skin care item were no longer Remove the only thing risen of the rich.Nowadays skin care item have come into ordinary citizen house as the popular vehicles, it is mentioned to spirit, the image of people Great effect is risen to.

Existing skin care item have the effects that whitening, moisturizing, nti-freckle, but existing skin care item are in the anti-inflammatory side of acting on that releives Face is unsatisfactory, this cannot meet the use demand of people.

Summary of the invention

The purpose of the present invention is to provide a kind of anti-inflammatory skin care item of releiving, to solve mentioned above in the background art ask Topic.

To achieve the above object, the invention provides the following technical scheme:

A kind of anti-inflammatory skin care item of releiving, the raw material including following parts by weight: 2.6-3.7 parts of cetostearyl alcohol, cetearyl alcohol 2.2-2.76 parts of base glucoside, 0.45-0.78 parts of saualane, 4.5-5.3 parts of jojoba seed oil, dimethyl silicone polymer 8.6- 9.2 parts, 1.65-2.18 parts of Butyrospermum parkii fruit rouge, 2-2.6 parts of lecithin, 1.26-1.66 parts of Cer NP, dipropylene glycol 12- 15.3 parts, 2.8-3.7 parts of sphingolipid, 3.1-3.85 parts of sucrose distearate, 2.2-2.46 parts of cholesterol, 8.2-8.8 parts of vaseline, 22.6-28.4 parts of mineral oil, 36.5-42.3 parts of water, 13.4-15.7 parts of panthenol, 6.6-7.9 parts of glycerol, glycine betaine 3.3-3.6 Part, 8.5-10.8 parts of 1,3- propylene glycol, 2.4-2.9 parts of allantoin, 5.6-6.1 parts of xanthan gum, 4.6-6.8 parts of acrylic acid, accumulated snow Careless glycosides 2.4-3.6 parts, 1.05-1.6 parts of Phosphoric acid monohexadecyl ester potassium, 0.6-0.96 parts of methyl hydroxybenzoate, dipotassium glycyrrhizinate 2.2-2.45 Part, root extract 3.1-4.6 parts of Radix Ophiopogonis, 4.8-5.7 parts of Phenoxyethanol, 6.7-7.5 parts of Sensiva SC50, tocopherol acetate 8.2-9.3 parts, 5.6-7.5 parts of tocopherol, 9.6-10.5 parts of bisabolol and 12-14.5 parts of tromethamine.

As a further solution of the present invention: lecithin uses hydrolecithin.

As a further solution of the present invention: Radix Ophiopogonis root extract is that Radix Ophiopogonis root is cleaned and is crushed to 80-110 mesh, so The mass fraction that 5-7 times of its weight is added afterwards is the ethanol solution refluxing extraction of 45-60%, is centrifuged, filters and is recovered under reduced pressure Ethyl alcohol obtains.

As a further solution of the present invention: the anti-inflammatory skin care item of releiving, the raw material including following parts by weight: spermaceti is hard 2.9-3.7 parts of lipidol, 2.42-2.76 parts of cetearyl glucoside, 0.58-0.78 parts of saualane, jojoba seed oil 4.8-5.3 Part, 8.8-9.2 parts of dimethyl silicone polymer, 1.92-2.18 parts of Butyrospermum parkii fruit rouge, 2.16-2.6 parts of lecithin, Cer NP 1.35-1.66 parts, 12.8-15.3 parts of dipropylene glycol, 3.1-3.7 parts of sphingolipid, 3.42-3.85 parts of sucrose distearate, gallbladder it is solid 2.29-2.46 parts of alcohol, 8.44-8.8 parts of vaseline, 24.7-28.4 parts of mineral oil, 38.6-42.3 parts of water, 14.1-15.7 parts of panthenol, 7.1-7.9 parts of glycerol, 3.45-3.6 parts of glycine betaine, 9.6-10.8 parts of 1,3- propylene glycol, 2.55-2.9 parts of allantoin, xanthan gum 5.76-6.1 parts, 5.3-6.8 parts of acrylic acid, 2.86-3.6 parts of asiaticosid, 1.26-1.6 parts of Phosphoric acid monohexadecyl ester potassium, oxybenzene first 0.77-0.96 parts of ester, 2.28-2.45 parts of dipotassium glycyrrhizinate, root extract 3.56-4.6 parts of Radix Ophiopogonis, Phenoxyethanol 5.14-5.7 Part, 7.1-7.5 parts of Sensiva SC50,8.66-9.3 parts of tocopherol acetate, 6.2-7.5 parts of tocopherol, bisabolol 10- 10.5 parts and tromethamine 12.9-14.5 parts.

As a further solution of the present invention: the anti-inflammatory skin care item of releiving, the raw material including following parts by weight: spermaceti is hard 3.54 parts of lipidol, 2.61 parts of cetearyl glucoside, 0.69 part of saualane, 5.15 parts of jojoba seed oil, polydimethylsiloxanes 8.95 parts of alkane, 2.06 parts of Butyrospermum parkii fruit rouge, 2.47 parts of lecithin, 1.52 parts of Cer NP, 14.5 parts of dipropylene glycol, sphingolipid 3.5 parts, 3.77 parts of sucrose distearate, 2.35 parts of cholesterol, 8.62 parts of vaseline, 26.9 parts of mineral oil, 40.5 parts of water, panthenol 14.78 parts, 7.56 parts of glycerol, 3.52 parts of glycine betaine, 10.4 parts of 1,3- propylene glycol, 2.82 parts of allantoin, 5.94 parts of xanthan gum, third 6.4 parts of olefin(e) acid, 3.32 parts of asiaticosid, 1.55 parts of Phosphoric acid monohexadecyl ester potassium, 0.84 part of methyl hydroxybenzoate, dipotassium glycyrrhizinate 2.36 Part, 4.37 parts of Radix Ophiopogonis root extract, 5.46 parts of Phenoxyethanol, 7.25 parts of Sensiva SC50,9.08 parts of tocopherol acetate, life Educate 7.3 parts of phenol, 10.2 parts of bisabolol and 13.7 parts of tromethamine.

The preparation method of the anti-inflammatory skin care item of releiving, the specific steps are as follows: raw material is mixed and stirs at low speed 15-26 Minute, then in homogenizer homogeneous 45-70 minute to get to finished product.

As a further solution of the present invention: the revolving speed stirred at low speed is 36-66rpm, and the homogeneous speed of homogenizer is 1440-1650rpm, homogenizing temperature are 38-46 degrees Celsius.

Compared with prior art, the beneficial effects of the present invention are: this product raw material sources are extensive, preparation process is simple, leads to It crosses and is used cooperatively various raw materials, the finished product of preparation has good anti-inflammatory effect of releiving, it can satisfy the use demand of people, With wide prospect of the application.

Specific embodiment

The technical solution of the patent is explained in further detail With reference to embodiment.

Embodiment 1

A kind of anti-inflammatory skin care item of releiving, the raw material including following parts by weight: 2.6 parts of cetostearyl alcohol, cetearyl Portugal 2.2 parts of glucosides, 0.45 part of saualane, 4.5 parts of jojoba seed oil, 8.6 parts of dimethyl silicone polymer, Butyrospermum parkii fruit rouge 1.65 Part, 2 parts of lecithin, 1.26 parts of Cer NP, 12 parts of dipropylene glycol, 2.8 parts of sphingolipid, 3.1 parts of sucrose distearate, gallbladder are solid 2.2 parts of alcohol, 8.2 parts of vaseline, 22.6 parts of mineral oil, 36.5 parts of water, 13.4 parts of panthenol, 6.6 parts of glycerol, 3.3 parts of glycine betaine, 1,3- 8.5 parts of propylene glycol, 2.4 parts of allantoin, 5.6 parts of xanthan gum, 4.6 parts of acrylic acid, 2.4 parts of asiaticosid, Phosphoric acid monohexadecyl ester potassium 1.05 parts, 0.6 part of methyl hydroxybenzoate, 2.2 parts of dipotassium glycyrrhizinate, 3.1 parts of Radix Ophiopogonis root extract, 4.8 parts of Phenoxyethanol, ethylhexyl 6.7 parts of glycerol, 8.2 parts of tocopherol acetate, 5.6 parts of tocopherol, 9.6 parts of bisabolol and 12 parts of tromethamine.Lecithin is adopted Use hydrolecithin.

The preparation method of the anti-inflammatory skin care item of releiving, the specific steps are as follows: raw material is mixed and stirs at low speed 19 points Clock, then in homogenizer homogeneous 48 minutes to get arriving finished product.

Embodiment 2

A kind of anti-inflammatory skin care item of releiving, the raw material including following parts by weight: 2.9 parts of cetostearyl alcohol, cetearyl Portugal 2.42 parts of glucosides, 0.58 part of saualane, 4.8 parts of jojoba seed oil, 8.8 parts of dimethyl silicone polymer, Butyrospermum parkii fruit rouge 1.92 Part, 2.16 parts of lecithin, 1.35 parts of Cer NP, 12.8 parts of dipropylene glycol, 3.1 parts of sphingolipid, sucrose distearate 3.42 Part, 2.29 parts of cholesterol, 8.44 parts of vaseline, 24.7 parts of mineral oil, 38.6 parts of water, 14.1 parts of panthenol, 7.1 parts of glycerol, glycine betaine 3.45 parts, 9.6 parts of 1,3- propylene glycol, 2.55 parts of allantoin, 5.76 parts of xanthan gum, 5.3 parts of acrylic acid, 2.86 parts of asiaticosid, 1.26 parts of Phosphoric acid monohexadecyl ester potassium, 0.77 part of methyl hydroxybenzoate, 2.28 parts of dipotassium glycyrrhizinate, 3.56 parts of Radix Ophiopogonis root extract, benzene oxygen 5.14 parts of ethyl alcohol, 7.1 parts of Sensiva SC50,8.66 parts of tocopherol acetate, 6.2 parts of tocopherol, 10 parts of bisabolol and ammonia 12.9 parts of butantriol.Radix Ophiopogonis root extract is that Radix Ophiopogonis root is cleaned and is crushed to 90 mesh, and the quality point of 6 times of its weight is then added The ethanol solution refluxing extraction that number is 54%, is centrifuged, filters and ethyl alcohol is recovered under reduced pressure and obtain.

The preparation method of the anti-inflammatory skin care item of releiving, the specific steps are as follows: mix raw material and with the revolving speed of 45rpm Stirring 22 minutes, then homogeneous 68 minutes in homogenizer, the homogeneous speed of homogenizer are 1530rpm, and homogenizing temperature is taken the photograph for 45 Family name's degree to get arrive finished product.

Embodiment 3

A kind of anti-inflammatory skin care item of releiving, the raw material including following parts by weight: 3.54 parts of cetostearyl alcohol, cetearyl Portugal 2.61 parts of glucosides, 0.69 part of saualane, 5.15 parts of jojoba seed oil, 8.95 parts of dimethyl silicone polymer, Butyrospermum parkii fruit rouge 2.06 parts, 2.47 parts of lecithin, 1.52 parts of Cer NP, 14.5 parts of dipropylene glycol, 3.5 parts of sphingolipid, sucrose distearate 3.77 parts, 2.35 parts of cholesterol, 8.62 parts of vaseline, 26.9 parts of mineral oil, 40.5 parts of water, 14.78 parts of panthenol, 7.56 parts of glycerol, 3.52 parts of glycine betaine, 10.4 parts of 1,3- propylene glycol, 2.82 parts of allantoin, 5.94 parts of xanthan gum, 6.4 parts of acrylic acid, asiaticosid 3.32 parts, 1.55 parts of Phosphoric acid monohexadecyl ester potassium, 0.84 part of methyl hydroxybenzoate, 2.36 parts of dipotassium glycyrrhizinate, Radix Ophiopogonis root extract 4.37 Part, 5.46 parts of Phenoxyethanol, 7.25 parts of Sensiva SC50,9.08 parts of tocopherol acetate, 7.3 parts of tocopherol, bisabolol 10.2 parts and 13.7 parts of tromethamine.Lecithin uses hydrolecithin.Radix Ophiopogonis root extract is that Radix Ophiopogonis root is cleaned and is crushed To 110 mesh, the ethanol solution refluxing extraction that the mass fraction of 6 times of its weight is 52% is then added, is centrifuged, filters and depressurize Recycling ethyl alcohol obtains.

The preparation method of the anti-inflammatory skin care item of releiving, the specific steps are as follows: mix raw material and with the revolving speed of 60rpm Stirring 20 minutes, then homogeneous 66 minutes in homogenizer, the homogeneous speed of homogenizer are 1650rpm, and homogenizing temperature is taken the photograph for 44 Family name's degree to get arrive finished product.

Embodiment 4

A kind of anti-inflammatory skin care item of releiving, the raw material including following parts by weight: 3.7 parts of cetostearyl alcohol, cetearyl Portugal 2.76 parts of glucosides, 0.78 part of saualane, 5.3 parts of jojoba seed oil, 9.2 parts of dimethyl silicone polymer, Butyrospermum parkii fruit rouge 2.18 Part, 2.6 parts of lecithin, 1.66 parts of Cer NP, 15.3 parts of dipropylene glycol, 3.7 parts of sphingolipid, sucrose distearate 3.85 Part, 2.46 parts of cholesterol, 8.8 parts of vaseline, 28.4 parts of mineral oil, 42.3 parts of water, 15.7 parts of panthenol, 7.9 parts of glycerol, glycine betaine 3.6 parts, 10.8 parts of 1,3- propylene glycol, 2.9 parts of allantoin, 6.1 parts of xanthan gum, 6.8 parts of acrylic acid, 3.6 parts of asiaticosid, spermaceti 1.6 parts of alcohol phosphate potassium, 0.96 part of methyl hydroxybenzoate, 2.45 parts of dipotassium glycyrrhizinate, 4.6 parts of Radix Ophiopogonis root extract, Phenoxyethanol 5.7 Part, 7.5 parts of Sensiva SC50,9.3 parts of tocopherol acetate, 7.5 parts of tocopherol, 10.5 parts of bisabolol and tromethamine 14.5 parts.Radix Ophiopogonis root extract is that Radix Ophiopogonis root is cleaned and is crushed to 80 mesh, and the mass fraction that 5 times of its weight is then added is 52% ethanol solution refluxing extraction, is centrifuged, filters and ethyl alcohol is recovered under reduced pressure and obtain.

Comparative example

As a comparison case using existing skin care item.

2000 volunteers are selected, stochastic averagina is divided into 5 groups, and the volunteer of 1-4 group uses the production of embodiment 1-4 respectively Product, 5 groups of volunteer use the product of comparative example, and using to use after face cleaning, once in the morning and once at night, for 3 weeks, volunteer is to certainly Oneself anti-inflammatory is releived effect marking, full marks are 10 points, and score is higher to indicate that anti-inflammatory effect of releiving is better, is recorded every group and is averaged Point, it the results are shown in Table 1.

Table 1

	1 group	2 groups	3 groups	4 groups	5 groups
						Group average mark	9.24	9.17	9.43	9.08	8.27

From table 1 it follows that 1-4 group is significantly larger than 5 groups in the anti-inflammatory scoring releived, show that product of the invention exists It is better than existing product in anti-inflammatory effect of releiving.

The volunteer of 1-5 group finds no the adverse reactions such as allergy, itch in use.

It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims Variation is included within the present invention.

In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims

1. a kind of anti-inflammatory skin care item of releiving, which is characterized in that the raw material including following parts by weight: 2.6-3.7 parts of cetostearyl alcohol, 2.2-2.76 parts of cetearyl glucoside, 0.45-0.78 parts of saualane, 4.5-5.3 parts of jojoba seed oil, polydimethylsiloxanes 8.6-9.2 parts of alkane, 1.65-2.18 parts of Butyrospermum parkii fruit rouge, 2-2.6 parts of lecithin, 1.26-1.66 parts of Cer NP, double third 12-15.3 parts of glycol, 2.8-3.7 parts of sphingolipid, 3.1-3.85 parts of sucrose distearate, 2.2-2.46 parts of cholesterol, vaseline 8.2-8.8 parts, 22.6-28.4 parts of mineral oil, 36.5-42.3 parts of water, 13.4-15.7 parts of panthenol, 6.6-7.9 parts of glycerol, beet 3.3-3.6 parts of alkali, 8.5-10.8 parts of 1,3- propylene glycol, 2.4-2.9 parts of allantoin, 5.6-6.1 parts of xanthan gum, acrylic acid 4.6- 6.8 parts, 2.4-3.6 parts of asiaticosid, 1.05-1.6 parts of Phosphoric acid monohexadecyl ester potassium, 0.6-0.96 parts of methyl hydroxybenzoate, glycyrrhizic acid two 2.2-2.45 parts of potassium, root extract 3.1-4.6 parts of Radix Ophiopogonis, 4.8-5.7 parts of Phenoxyethanol, 6.7-7.5 parts of Sensiva SC50, life Educate 8.2-9.3 parts of phenol acetic acid esters, 5.6-7.5 parts of tocopherol, 9.6-10.5 parts of bisabolol and 12-14.5 parts of tromethamine.

2. anti-inflammatory skin care item of releiving according to claim 1, which is characterized in that the lecithin uses hydrolecithin.

3. anti-inflammatory skin care item of releiving according to claim 1 or 2, which is characterized in that the Radix Ophiopogonis root extract is Radix Ophiopogonis Root is cleaned and is crushed to 80-110 mesh, and the ethanol solution that the mass fraction that 5-7 times of its weight is then added is 45-60% flows back It extracts, is centrifuged, filters and ethyl alcohol is recovered under reduced pressure and obtain.

4. anti-inflammatory skin care item of releiving according to claim 1, which is characterized in that the raw material including following parts by weight: spermaceti 2.9-3.7 parts of stearyl alcohol, 2.42-2.76 parts of cetearyl glucoside, 0.58-0.78 parts of saualane, jojoba seed oil 4.8- 5.3 parts, 8.8-9.2 parts of dimethyl silicone polymer, 1.92-2.18 parts of Butyrospermum parkii fruit rouge, 2.16-2.6 parts of lecithin, neural acyl 3 1.35-1.66 parts of amine, 12.8-15.3 parts of dipropylene glycol, 3.1-3.7 parts of sphingolipid, 3.42-3.85 parts of sucrose distearate, 2.29-2.46 parts of cholesterol, 8.44-8.8 parts of vaseline, 24.7-28.4 parts of mineral oil, 38.6-42.3 parts of water, panthenol 14.1- 15.7 parts, 7.1-7.9 parts of glycerol, 3.45-3.6 parts of glycine betaine, 9.6-10.8 parts of 1,3- propylene glycol, 2.55-2.9 parts of allantoin, 5.76-6.1 parts of xanthan gum, 5.3-6.8 parts of acrylic acid, 2.86-3.6 parts of asiaticosid, 1.26-1.6 parts of Phosphoric acid monohexadecyl ester potassium, 0.77-0.96 parts of methyl hydroxybenzoate, 2.28-2.45 parts of dipotassium glycyrrhizinate, root extract 3.56-4.6 parts of Radix Ophiopogonis, Phenoxyethanol 5.14-5.7 parts, 7.1-7.5 parts of Sensiva SC50,8.66-9.3 parts of tocopherol acetate, 6.2-7.5 parts of tocopherol, red do not have 10-10.5 parts and tromethamine 12.9-14.5 parts of medicine alcohol.

5. anti-inflammatory skin care item of releiving according to claim 1, which is characterized in that the raw material including following parts by weight: spermaceti 3.54 parts of stearyl alcohol, 2.61 parts of cetearyl glucoside, 0.69 part of saualane, 5.15 parts of jojoba seed oil, poly dimethyl silicon 8.95 parts of oxygen alkane, 2.06 parts of Butyrospermum parkii fruit rouge, 2.47 parts of lecithin, 1.52 parts of Cer NP, 14.5 parts of dipropylene glycol, sheath It is 3.5 parts of rouge, 3.77 parts of sucrose distearate, 2.35 parts of cholesterol, 8.62 parts of vaseline, 26.9 parts of mineral oil, 40.5 parts of water, general 14.78 parts of alcohol, 7.56 parts of glycerol, 3.52 parts of glycine betaine, 10.4 parts of 1,3- propylene glycol, 2.82 parts of allantoin, 5.94 parts of xanthan gum, 6.4 parts of acrylic acid, 3.32 parts of asiaticosid, 1.55 parts of Phosphoric acid monohexadecyl ester potassium, 0.84 part of methyl hydroxybenzoate, dipotassium glycyrrhizinate 2.36 Part, 4.37 parts of Radix Ophiopogonis root extract, 5.46 parts of Phenoxyethanol, 7.25 parts of Sensiva SC50,9.08 parts of tocopherol acetate, life Educate 7.3 parts of phenol, 10.2 parts of bisabolol and 13.7 parts of tromethamine.

6. a kind of preparation method of anti-inflammatory skin care item of releiving a method as claimed in any one of claims 1 to 5, which is characterized in that specific steps It is as follows: raw material is mixed and stirs at low speed 15-26 minute, then in homogenizer homogeneous 45-70 minutes to get to finished product.

7. the preparation method of anti-inflammatory skin care item of releiving according to claim 6, which is characterized in that turn stirred at low speed Speed is 36-66rpm, and the homogeneous speed of homogenizer is 1440-1650rpm, and homogenizing temperature is 38-46 degrees Celsius.