CN106344444A - Anti-aging cream and preparation method thereof - Google Patents

Anti-aging cream and preparation method thereof Download PDF

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Publication number
CN106344444A
CN106344444A CN201610729191.4A CN201610729191A CN106344444A CN 106344444 A CN106344444 A CN 106344444A CN 201610729191 A CN201610729191 A CN 201610729191A CN 106344444 A CN106344444 A CN 106344444A
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extract
parts
skin
preparation
raw material
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杨子中
朱丽刚
黄书允
章方强
祁艳辉
范红军
沈立波
高云霞
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Andy Biotechnology (beijing) Co Ltd
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Andy Biotechnology (beijing) Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
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    • A61K8/34Alcohols
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    • A61K8/41Amines
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    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
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    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract

The invention discloses an anti-aging cream and a preparation method thereof. The anti-aging cream is prepared from the following raw materials: cetostearyl alcohol, cetearyl glucoside, PEG-100 stearate, squalane, coconut oil, avocado grease, polydimethylsiloxane, propylparaben, methylparaben, glycerol, butanediol, carbomer, triethanolamine, a golden camomile extract, ceramide, lecithin, propanediol, a radix rehmanniae root extract, a giant knotweed extract, a kudzu root extract, a soybean extract, a safflower extract, a pomegranate fruit extract, a snakeroot extract, an angelica extract, methyl isothiazolinone, phenoxyethanol, essence and water. By organically combining the raw materials, the anti-aging cream is capable of effectively preventing free radicals from generation and removing excessive harmful free radicals in the human body, and has the functions of removing speckles, promoting the formation of skin cutin, keeping the elasticity of the skin and enhancing the aging resistance of the skin.

Description

A kind of anti-ageing frost and preparation method thereof
Technical field
The present invention relates to cosmetic field is and in particular to a kind of anti-ageing frost and preparation method thereof.
Background technology
At present, defying age has become main market players, and aging has many reasons, wherein mainly has depositing of interior free yl , telomerase activation disappearance, macromolecules cross-linking etc..And the presence of interior free yl be lead to skin aging phenomenon produce main Reason.Free Radical in the polyunsaturated fatty acid of cell membrane, forms lipid peroxide, the material such as malonaldehyde of generation with Protein on cell membrane acts on and generates brown pigment, is deposited in skin, forms mottle.Free radical also can make in epiderm skin Collagen protein, elastic fiberss crosslinking and degeneration, become fragile and follow the string.Now it is generally used for the raw material that the product of free radical resisting uses Mainly there are Glutathione, carotene, vitamin c vitamin e etc., these raw materials primarily serve antioxidative effect, hinder freely Base forms peroxide, and effect is more single.
Additionally, the people that there is 40%-70% in the whole world have sensitivity skin be inclined to, and life-time service contain preservative, pigment and The skin care item of mineral oil are easily caused skin and the allergic phenomenas such as erythema, decortication, pimple.And sensitivity skin consumer is typically The higher colony of the consuming capacity, so the anti-aging cosmetics without preservative, artificial color and mineral oil for the exploitation are consumption The one big demand of person.
Content of the invention
It is an object of the invention to provide a kind of do not contain preservative, artificial color and mineral oil, and interior free yl can be removed Promote anti-ageing frost of collagen protein synthesis and preparation method thereof.
The purpose of the present invention is achieved through the following technical solutions:
A kind of anti-ageing frost, including the raw material of following weight parts: cetearyl alcohol 2-9 part, cetearyl glucoside 3-7 Part, peg-100 stearate 2-4 part, squalane 0.2-0.4 part, Oleum Cocois 1-3 part, shea fruit fat 3-9 part, poly dimethyl Siloxanes 0.2-0.3 part, propyl hydroxybenzoate 0.2-0.4 part, methyl hydroxybenzoate 0.2-0.4 part, glycerol 0.2-0.3 part, butanediol 0.2- 0.3 part, Carbomer 3-5 part, triethanolamine 0.2-0.4 part, golden yellow camomile extract 0.2-0.4 part, ceramide 3 0.2- 0.3 part, lecithin 0.2-0.3 part, propylene glycol 0.3-0.4 part, Radix Rehmanniae root extract 4-5 part, Rhizoma Polygoni Cuspidati extract 2-5 part, Radix Puerariae Extract 2-4 part, soybean extract 2-4 part, Flos Carthami extract 2-9 part, Punica granatum L. berry extract 4-7 part, black cohosh extract 3-5 part, Radix Angelicae Sinensis extract 2-2.5 part, Methylisothiazolinone 0.2-0.25 part, phenoxyethanol 0.2-0.25 part, essence 0.2- 0.4 part, water 10-50 part.
Further, described anti-ageing frost, including the raw material of following weight parts: 6 parts of cetearyl alcohol, cetearyl glucose 5 parts of glycosides, 3 parts of peg-100 stearate, 0.3 part of squalane, 2 parts of Oleum Cocois, 6 parts of shea fruit fat, polydimethylsiloxane 0.25 part, 0.3 part of propyl hydroxybenzoate, 0.3 part of methyl hydroxybenzoate, 0.25 part of glycerol, 0.25 part of butanediol, 4 parts of Carbomer, triethanolamine 0.3 part, 0.3 part of golden yellow camomile extract, 0.25 part of ceramide 3,0.25 part of lecithin, 0.35 part of propylene glycol, Radix Rehmanniae 4.5 parts of extract, 3 parts of Rhizoma Polygoni Cuspidati extract, 3 parts of Radix Puerariae extract, 3 parts of soybean extract, 6 parts of Flos Carthami extract, Punica granatum L. carry Take 5 parts of thing, 4 parts of rattleroot root extract, 2.25 parts of Radix Angelicae Sinensis extract, 0.2 part of Methylisothiazolinone, phenoxyethanol 0.2 Part, 0.3 part of essence, 27 parts of water.
The preparation method of anti-ageing frost described above, comprises the following steps:
(1) Oleum Cocois and shea fruit fat are added to the water, obtain mixed liquor, mixed liquor is carried out heat to obtain aqueous phase a;
(2) by cetearyl alcohol, cetearyl glucoside, peg-100 stearate and squalane, mix homogeneously, plus Hot standby oil b;
(3) standby oil b is added in aqueous phase a, sequentially add remaining each raw material, stir to obtain described anti-ageing frost.
Further, in step (1), described it is heated to be: mixed liquor is heated to 80-90 DEG C, and heats at this temperature 10-20min.
Further, in step (2), described it is heated to be: by each raw material in step (2) under conditions of stirring, heating To being completely dissolved.Temperature during heating can be adjusted, and heats while stirring in heating, each raw material to step (2) It is completely dissolved.Stirring contributes to the abundant dissolving of raw material, does not have strict demand to the speed of stirring.
Further, in step (3), after standby oil b is added in aqueous phase a, first carry out sterilization treatment and add residue respectively Raw material.Homogenizing is also referred to as and is homogenized, and is to make dispersion micronized in suspension (or emulsion) system, the processing procedure of homogenization, This process acts the effect reducing dispersion yardstick and improving dispersion distributing homogeneity simultaneously.
Further, described sterilization treatment is to adopt high pressure homogenizer, in the condition for 180mpa-200mpa for the operating pressure Under carry out sterilization treatment 3-10min.Process through high pressure homogenize and the granule of medium can be made extremely to refine, and the product after homogenizing The advantages of high glue, high stability can not also be precipitated, so that the outward appearance of finished product also substantially improves.
Further, in step (3), the mixing speed of described stirring is 100-200r/min, and mixing time is 20- 30min.
Cetearyl alcohol, English name is cetearyl alcohol, and trade name is cetostearyl alcohol cetearyl alcohol, White crystalline solid, granule or wax stone shape, savory.There is suppression greasy feeling, reduce wax class raw material stickiness, stable cosmetic breast Colloid etc. acts on;Be applied to all kinds of cosmetics, as substrate, it is particularly suitable for cream and emulsion.
Cetearyl glucoside another name is the many glycosides of cetearyl glucose, be colourless to weak yellow liquid or mastic, property Matter is stable, water soluble, and the compatibility of skin is relatively good, has excellent decontamination, foaming, steady bubble, emulsifying, dispersion, solubilising Ability.
Peg-100 stearate refers to polyoxyethylene 100 stearate, is a kind of emulsifying agent, has excellent emulsifying, divides Scattered, solubilized effect.
Squalane is that the Squalene extracting from hydrogenated hydro carbons grease is hydrogenated is obtained a kind of squalene extracting of excellent performance, Therefore also known as eepwater shark liver oil, the chemical stability of squalane is higher, has preferable affinity to skin, will not cause allergy And stimulation, and other active components in formula can be accelerated to permeate in skin.Squalane, can be melted with the sebum film of mankind itself It is integrated, forms one layer of natural barrier in skin surface, additionally, it can also promote the propagation of skin base cell, to delaying Skin aging, improving and eliminate chloasma all has obvious physiologic effect.Squalane also can make skin pore open, and promotes blood Microcirculation, promotes the metabolism of cell, helps repair damaged cell.
Oleum Cocois are derived from Cortex cocois radiciss jerky, for white or faint yellow fat.Oleum Cocois have very strong oxidation resistance, can help Body of helping others prevents the generation of free radical.There is skin care, adjustment smegma, smooth away wrinkles and acne effect.
Butyrospermum parkii fruit fat extracts from the African shea seeds of trees, can assist in keeping moisture as skin conditioning agent, in skin Skin surface forms protective barrier, reduces water loss.
Polydimethylsiloxane is also referred to as dimethicone, is a kind of organic silicon materials of hydrophobic class.There is good shield Skin function, belongs to the synthetic ester oil in cosmetic material.In cosmetics, there is greasy property, anti-ultraviolet effect, breathe freely Property is good, has obvious dust reduction capability.
Propyl hydroxybenzoate white crystals, have special odor.It is dissolved in ethanol, ether, acetone and other organic solvent.Main in cosmetics Preservative to be made and antibacterial use.
Methyl hydroxybenzoate white crystalline powder or colourless crystallization, are mainly used as preservative and antibacterial in cosmetics.
Glycerol is clear and bright thick liquid also known as glycerol, and glycerol has functions that to keep skin wet.
Butanediol often does wetting agent in cosmetics and solvent uses, and has superpower moisture-keeping function, salubrious and no sticky sense.
Carbomer is white loose sprills, is commonly used for thickening agent in cosmetics.
Triethanolamine can regard the trihydroxy substituent of triethylamine as, be colourless to pale yellow transparent thick liquid, It is used as emulsifying agent, wetting agent or ph poising agent in cosmetics.
Golden yellow camomile extract has Lavender Extract of releiving, and increases cuticular effect.Golden yellow used in the present invention Camomile extract is bought in Shaanxi Kang Yue bio tech ltd.
Ceramide, also known as sphingolipid, is a kind of lipid being present in skin, in epidermal keratinocytes layer formation process Play an important role.When drying, desquamation, cracking phenomena in skin, when the barrier function of skin substantially reduces, to skin Supplement ceramide and can recover rapidly moisturizing and barrier function.Ceramide can strengthen skin anti-aging function, makes skin keep Elasticity, smooth careful, reduce facial wrinkles and formed.
Lecithin is also called lecithin, is described as " threeth nutrient " arranged side by side with protein, vitamin.Lecithin is people The indispensable material of each cell of body, if lack, the regeneration capacity of Skin Cell will be reduced, lead to pachylosiies, There is wrinkle.If suitably absorbing lecithin, skin regeneration vigor just can ensure, along with the good hydrophilic of lecithin and parent Oiliness, skin is certainly just glossy.
Propylene glycol can be used as wetting agent with glycerol or Sorbitol cooperation in cosmetics, toothpaste and fancy soap.
Radix Rehmanniae extract is the fresh or dried root of scrophulariaceae rehmannia glutinosa plant.Polysaccharide in Radix Rehmanniae has beauty and skin care Effect, can remove and excessively be harmful to oxygen-derived free radicals, delay skin aging in human body.Radix Rehmanniae extract of the present invention buy in Xi'an branch company of Bioisystech Co., Ltd of Tianrui.
Rhizoma Polygoni Cuspidati extract to and pigment cell's activity have good inhibiting effect.In addition Rhizoma Polygoni Cuspidati extract is lived to macrophage Property has facilitation, and in cell culture, macrophage can swallow melanin, and therefore Rhizoma Polygoni Cuspidati extract is subtracted by two aspects Few melanic content, can be used for whitening class cosmetics;Rhizoma Polygoni Cuspidati extract has inhibitory action to elastoser it is adaptable to crease-resistant Class skin care item.Rhizoma Polygoni Cuspidati extract of the present invention is bought in Zhejiang Sheng Shi biotechnology company.
Radix Puerariae extract derives from the dry root of legume pueraria lobata.The flavones ingredient pgi of separation and purification from Radix Puerariae The erythrocyte hemolysis that oxidative damage causes can be significantly inhibited, there is antioxidative effect.Radix Puerariae extract purchase of the present invention Buy in Zhejiang Sheng Shi biotechnology company.
The main component of soybean extract is soybean isoflavone, has and prevents wrinkle from producing, the effect of slow down aging.This Outward, soybean extract also has skin moisturizing, pore refining, compact skin, makes skin high resilience, removes skin speckle, light Change effect of mottle.Soybean extract of the present invention is bought in Zhejiang Sheng Shi biotechnology company.
Flos Carthami extract can eliminate free radical, the hyaluronic acid depolymerization of suppression free radical induction and lipid peroxidation, Protection cell membrane, delays the aging of body.Flos Carthami extract of the present invention buys that to receive health biotechnology in Guangzhou extraction limited Company.
The effective ingredient of Punica granatum L. berry extract is anthocyanidin, Punica granatum L. polyphenol, ellagic acid, and these compositions are all extremely strong antioxygens Compound matter, can effective delaying skin aging, moisturizing, crease-resistant.Punica granatum L. berry extract of the present invention is bought in the life of Xi'an Tianrui Thing Technology Co., Ltd..
Also known as Black Cohosh P.E, Black Cohosh P.E is the root of cimicifuga romose l. to black cohosh extract Stem extract, is brown-black powder.Black Cohosh P.E has antibacterial, blood pressure lowering, suppression cardiac muscle, decreased heart rate, sedation;Black Rhizoma Cimicifugae extract is effective in cure to arthritis and osteoporosis.Black cohosh extract of the present invention is bought in Xi'an Tianrui Bioisystech Co., Ltd.
Radix Angelicae Sinensis extract, Radix Angelicae Sinensis contain the organic principles such as a large amount of volatile oil, vitamin, organic acid and trace element makes it have There are good its cosmetic values.Radix Angelicae Sinensis suppress the active function of TYR enzyme very strong, can suppress melanic formation, yellowish-brown to treating The pigmented dermatosis such as speckle, freckle have good effect, can play defying age and effect of beauty treatment.
Methylisothiazolinone is a kind of efficient germicide, and the growth for suppression microorganism has good effect, permissible Suppression antibacterial, funguses, the growth of mycete, this product can be directly added into the neck such as personal-care supplies, cosmetics, coating, paper pulp Domain.
Phenoxyethanol is a kind of organic compound being frequently used for skin-protection product, generally plays preservative in cosmetics Effect.
Essence is by the concentration aromatic oil imitating fruit and natural perfume material smell of synthetic, is a kind of artificial perfume. Essence taste jasmin of the present invention, Rose Essentielle or fruital.
The invention has the benefit that the cetearyl glucoside comprising in anti-ageing frost of the present invention, squalane Relatively good with the compatibility of skin, and there is very strong dirt-removing power;Oleum Cocois, Radix Rehmanniae extract, Radix Puerariae extract can be prevented Stop the generation of free radical, remove excessive harmful free radicals in human body;Butyrospermum parkii fruit fat, polydimethylsiloxane, glycerol, fourth Glycol, triethanolamine, propylene glycol have functions that moisturizing, dust-proof;Propyl hydroxybenzoate, methyl hydroxybenzoate, black cohosh extract, methyl Isothiazolone and phenoxyethanol have functions that anti-corrosion, antibacterial, sterilization;Golden yellow camomile extract, ceramide, lecithin Fat, Rhizoma Polygoni Cuspidati extract, soybean extract, Flos Carthami extract, Punica granatum L. berry extract and Radix Angelicae Sinensis extract contribute to the formation of cutin, Desalination mottle makes skin keep elasticity, strengthens the function of skin anti-aging, cetearyl alcohol, peg-100 stearate, Carbomer Use as substrate, there is the effect of thickening.Each raw material in anti-ageing frost of the present invention is organically combined together can be effective Play the generation preventing free radical, remove the free radical being excessively harmful in human body, and there is speckle dispelling, promote skin keratin Formed, make skin keep the function of elastic reinforcement skin anti-aging.
Sterilization treatment is carried out using high pressure homogenizer, using high pressure homogenizer in the production method of anti-ageing frost of the present invention Carry out sterilization treatment can make granule extremely refinement so as to get product it is easier to skin absorption, and make the visual effect of product More preferably.
Specific embodiment
Embodiment one
A kind of anti-ageing frost, including the raw material of following weight parts: cetearyl alcohol 2kg, cetearyl glucoside 3kg, Peg-100 stearate 2kg, squalane 0.2kg, Oleum Cocois 1kg, shea fruit fat 3kg, polydimethylsiloxane 0.2kg, hydroxyl Phenylpropyl alcohol ester 0.2kg, methyl hydroxybenzoate 0.2kg, glycerol 0.2kg, butanediol 0.2kg, Carbomer 3kg, triethanolamine 0.2kg, golden yellow Camomile extract 0.2kg, ceramide 3 0.2kg, lecithin 0.2kg, propylene glycol 0.3kg, Radix Rehmanniae root extract 4kg, Rhizoma Polygoni Cuspidati Extract 2kg, Radix Puerariae extract 2kg, soybean extract 2kg, Flos Carthami extract 2kg, Punica granatum L. berry extract 4kg, rattleroot Extract 3kg, Radix Angelicae Sinensis extract 2kg, Methylisothiazolinone 0.2kg, phenoxyethanol 0.2kg, essence 0.2kg, water 10kg.
The preparation method of anti-ageing frost described above, comprises the following steps:
(1) Oleum Cocois and shea fruit fat are added to the water, obtain mixed liquor, mixed liquor is heated to 80 DEG C, and here At a temperature of heating 10min obtain aqueous phase a;
(2) by cetearyl alcohol, cetearyl glucoside, peg-100 stearate and squalane, mix homogeneously, so Stir under conditions of heating afterwards and be all completely dissolved to each raw material, obtain standby oil b;
(3) standby oil b is added in aqueous phase a, then adopt high pressure homogenizer, under conditions of operating pressure is for 180mpa Sterilization treatment 3min, sequentially adds remaining each raw material, and low whipping speed is stirring 20min under conditions of 100r/min, stirring Mix homogeneously obtains described anti-ageing frost.
Embodiment two
A kind of anti-ageing frost, including the raw material of following weight parts, cetearyl alcohol 6kg, cetearyl glucoside 5kg, Peg-100 stearate 3kg, squalane 0.3kg, Oleum Cocois 2kg, shea fruit fat 6kg, polydimethylsiloxane 0.25kg, Propyl hydroxybenzoate 0.3kg, methyl hydroxybenzoate 0.3kg, glycerol 0.25kg, butanediol 0.25kg, Carbomer 4kg, triethanolamine 0.3kg, Golden yellow camomile extract 0.3kg, ceramide 3 0.25kg, lecithin 0.25kg, propylene glycol 0.35kg, Radix Rehmanniae root extract 4.5kg, Rhizoma Polygoni Cuspidati extract 3kg, Radix Puerariae extract 3kg, soybean extract 3kg, Flos Carthami extract 6kg, Punica granatum L. berry extract 5kg, rattleroot root extract 4kg, Radix Angelicae Sinensis extract 2.25kg, Methylisothiazolinone 0.2kg, phenoxyethanol 0.2kg, perfume (or spice) Smart 0.3kg, water 27kg.
The preparation method of anti-ageing frost described above, comprises the following steps:
(1) Oleum Cocois and shea fruit fat are added to the water, obtain mixed liquor, mixed liquor is heated to 85 DEG C, and here At a temperature of heating 15min obtain aqueous phase a;
(2) by cetearyl alcohol, cetearyl glucoside, peg-100 stearate and squalane, mix homogeneously, so Stir under conditions of heating afterwards and be all completely dissolved to each raw material, obtain standby oil b;
(3) standby oil b is added in aqueous phase a, then adopt high pressure homogenizer, under conditions of operating pressure is for 190mpa Sterilization treatment 5min, sequentially adds remaining each raw material, and low whipping speed is stirring 25min under conditions of 150r/min, stirring Mix homogeneously obtains described anti-ageing frost.
Embodiment three
A kind of anti-ageing frost, including the raw material of following weight parts: cetearyl alcohol 9kg, cetearyl glucoside 7kg, Peg-100 stearate 4kg, squalane 0.4kg, Oleum Cocois 3kg, shea fruit fat 9kg, polydimethylsiloxane 0.3kg, hydroxyl Phenylpropyl alcohol ester 0.4kg, methyl hydroxybenzoate 0.4kg, glycerol 0.3kg, butanediol 0.3kg, Carbomer 5kg, triethanolamine 0.4kg, golden yellow Camomile extract 0.4kg, ceramide 3 0.3kg, lecithin 0.3kg, propylene glycol 0.4kg, Radix Rehmanniae root extract 5kg, Rhizoma Polygoni Cuspidati Extract 5kg, Radix Puerariae extract 4kg, soybean extract 4kg, Flos Carthami extract 9kg, Punica granatum L. berry extract 7kg, rattleroot Extract 5kg, Radix Angelicae Sinensis extract 2.5kg, Methylisothiazolinone 0.25kg, phenoxyethanol 0.25kg, essence 0.4kg, water 50kg.
The preparation method of anti-ageing frost described above, comprises the following steps:
(1) Oleum Cocois and shea fruit fat are added to the water, obtain mixed liquor, mixed liquor is heated to 90 DEG C, and here At a temperature of heating 20min obtain aqueous phase a;
(2) by cetearyl alcohol, cetearyl glucoside, peg-100 stearate and squalane, mix homogeneously, so Stir under conditions of heating afterwards and be all completely dissolved to each raw material, obtain standby oil b;
(3) standby oil b is added in aqueous phase a, then adopt high pressure homogenizer, under conditions of operating pressure is for 200mpa Sterilization treatment 10min, sequentially adds remaining each raw material, and low whipping speed is stirring 30min under conditions of 200r/min, stirring Mix homogeneously obtains described anti-ageing frost.
The present embodiment 2 be embodied as case: test number is 80 people, is divided into 4 groups, every group of 20 people, and test period is 28 My god, with skin elasticity as test index.
Test method: before smearing sample, experimenter uses the gentle cleaning agent of identical to clean face, in experimenter face Left and right sides symmetric position selectes about 5 × 5cm2The region of size, as Experimental Area, is smeared about 0.5g on the left of face and is implemented The anti-ageing frost of example 2, as blank district on the right side of face, usage frequency is sooner or later respectively once, continuously uses daily.
Before the anti-ageing frost using the present invention, detected with reviscometerrv600 skinanalysis apparatus in test zone Each test position and the elastic r2 value of control zone;Then smear again anti-ageing white 7 days of the present invention, 14 days, 21 days, 28 Each test position elasticity r2 value is detected with reviscometerrv600 skinanalysis apparatus again respectively at these positions after it.
Result of the test: 80 experimental test persons, using anti-ageing white 28 days described in embodiment 2, the skin elasticity of test position Apparently higher than the skin elasticity at comparison position, and contrast 7 days, 14 days, 21 days, the skin elasticity test result of 28 days, draw: with The growth of time, the face elasticity of test position is gradually stepping up.
The present invention is not limited to above-mentioned preferred forms, and anyone can show that under the enlightenment of the present invention other are various The product of form, however, making any change in its details, every have technical scheme identical or similar to the present application, It is within the scope of the present invention.

Claims (8)

1. a kind of anti-ageing frost is it is characterised in that include the raw material of following weight parts: cetearyl alcohol 2-9 part, cetearyl Portugal Glucosides 3-7 part, peg-100 stearate 2-4 part, squalane 0.2-0.4 part, Oleum Cocois 1-3 part, shea fruit fat 3-9 part, poly- Dimethyl siloxane 0.2-0.3 part, propyl hydroxybenzoate 0.2-0.4 part, methyl hydroxybenzoate 0.2-0.4 part, glycerol 0.2-0.3 part, fourth two Alcohol 0.2-0.3 part, Carbomer 3-5 part, triethanolamine 0.2-0.4 part, golden yellow camomile extract 0.2-0.4 part, ceramide 30.2-0.3 part, lecithin 0.2-0.3 part, propylene glycol 0.3-0.4 part, Radix Rehmanniae root extract 4-5 part, Rhizoma Polygoni Cuspidati extract 2-5 part, Radix Puerariae extract 2-4 part, soybean extract 2-4 part, Flos Carthami extract 2-9 part, Punica granatum L. berry extract 4-7 part, rattleroot carry Take thing 3-5 part, Radix Angelicae Sinensis extract 2-2.5 part, Methylisothiazolinone 0.2-0.25 part, phenoxyethanol 0.2-0.25 part, essence 0.2-0.4 part, water 10-50 part.
2. according to claim 1 a kind of anti-ageing frost it is characterised in that include following weight parts raw material: cetearyl alcohol 6 Part, 5 parts of cetearyl glucoside, 3 parts of peg-100 stearate, 0.3 part of squalane, 2 parts of Oleum Cocois, shea fruit fat 6 Part, 0.25 part of polydimethylsiloxane, 0.3 part of propyl hydroxybenzoate, 0.3 part of methyl hydroxybenzoate, 0.25 part of glycerol, 0.25 part of butanediol, 4 parts of Carbomer, 0.3 part of triethanolamine, 0.3 part of golden yellow camomile extract, 0.25 part of ceramide 3,0.25 part of lecithin, third 0.35 part of glycol, 4.5 parts of Radix Rehmanniae root extract, 3 parts of Rhizoma Polygoni Cuspidati extract, 3 parts of Radix Puerariae extract, 3 parts of soybean extract, Flos Carthami carry Take 6 parts of thing, 5 parts of Punica granatum L. berry extract, 4 parts of rattleroot root extract, 2.25 parts of Radix Angelicae Sinensis extract, Methylisothiazolinone 0.2 part, 0.2 part of phenoxyethanol, 0.3 part of essence, 27 parts of water.
3. the preparation method of the described anti-ageing frost of one of claim 1-2 is it is characterised in that comprise the following steps:
(1) Oleum Cocois and shea fruit fat are added to the water, obtain mixed liquor, mixed liquor is carried out heat to obtain aqueous phase a;
(2) by cetearyl alcohol, cetearyl glucoside, peg-100 stearate and squalane, mix homogeneously, heat Standby oil b;
(3) standby oil b is added in aqueous phase a, sequentially add remaining each raw material, stir to obtain described anti-ageing frost.
4. the preparation method of anti-ageing frost it is characterised in that in step (1), described is heated to be according to claim 3: will mix Close liquid and be heated to 80-90 DEG C, and heat 10-20min at this temperature.
5. the preparation method of anti-ageing frost it is characterised in that in step (2), described is heated to be according to claim 3: will walk Suddenly each raw material in (2), under conditions of stirring, is heated to being completely dissolved.
6. the preparation method of anti-ageing frost it is characterised in that in step (3), standby oil b is added water according to claim 3 After in phase a, first carry out sterilization treatment and add remaining each raw material.
7. according to claim 6 anti-ageing frost preparation method it is characterised in that described sterilization treatment is to adopt high pressure homogenize Machine, carries out sterilization treatment 3-10min under conditions of operating pressure is for 180mpa-200mpa.
8. according to claim 3 the preparation method of anti-ageing frost it is characterised in that in step (3), the stirring speed of described stirring Spend for 100-200r/min, mixing time is 20-30min.
CN201610729191.4A 2016-08-25 2016-08-25 Anti-aging cream and preparation method thereof Pending CN106344444A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107242981A (en) * 2017-05-12 2017-10-13 济南橡树叶生物科技有限公司 A kind of toner and preparation method thereof
CN111714400A (en) * 2020-07-27 2020-09-29 广东真丽斯化妆品有限公司 Cosmetic with anti-aging and repairing effects and preparation method thereof
CN112220725A (en) * 2020-10-15 2021-01-15 广东一芙化妆品有限公司 DIY moisturizer and preparation method thereof
CN112999122A (en) * 2021-02-24 2021-06-22 江西建昌帮食疗科技有限公司 Anti-wrinkle moisturizing eye cream and preparation method thereof
CN113520966A (en) * 2021-07-21 2021-10-22 北京净嘉生物科技有限公司 Anti-aging long-hair dioscorea opposita essence and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107242981A (en) * 2017-05-12 2017-10-13 济南橡树叶生物科技有限公司 A kind of toner and preparation method thereof
CN111714400A (en) * 2020-07-27 2020-09-29 广东真丽斯化妆品有限公司 Cosmetic with anti-aging and repairing effects and preparation method thereof
CN112220725A (en) * 2020-10-15 2021-01-15 广东一芙化妆品有限公司 DIY moisturizer and preparation method thereof
CN112999122A (en) * 2021-02-24 2021-06-22 江西建昌帮食疗科技有限公司 Anti-wrinkle moisturizing eye cream and preparation method thereof
CN113520966A (en) * 2021-07-21 2021-10-22 北京净嘉生物科技有限公司 Anti-aging long-hair dioscorea opposita essence and preparation method thereof

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