CN109453050A - A kind of anti-inflammatory anti-acne skin care item and preparation method thereof - Google Patents
A kind of anti-inflammatory anti-acne skin care item and preparation method thereof Download PDFInfo
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- CN109453050A CN109453050A CN201811467560.2A CN201811467560A CN109453050A CN 109453050 A CN109453050 A CN 109453050A CN 201811467560 A CN201811467560 A CN 201811467560A CN 109453050 A CN109453050 A CN 109453050A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses a kind of anti-inflammatory anti-acne skin care item and preparation method thereof, the raw material including following parts by weight: 34-41 parts of water, 15-18.6 parts of glycerol, 22.4-27.8 parts of butanediol, -5 2.15-2.86 parts of myristoyl hexapeptide, -2 1.65-2.1 parts of acetyl group tetrapeptide, 2.4-2.9 parts of glucan, 4.2-5.9 parts of kuh-seng root extract, 7.6-8.8 parts of carbomer, 10.5-15.3 parts of Phenoxyethanol, 4.5-6.2 parts of Sensiva SC50,5.5-7.4 parts of methyl hydroxybenzoate, 6.4-7.7 parts of ethyl hydroxy benzoate and 3.6-6.8 parts of triethanolamine.This product raw material sources are extensive, and preparation process is simple, and by being used cooperatively various raw materials, the finished product of preparation has both the effect of good anti-inflammatory and anti-acne, can satisfy the use demand of people, have positive social benefit.
Description
Technical field
The present invention relates to skin care field, specifically a kind of anti-inflammatory anti-acne skin care item.
Background technique
With the development of economy, increasingly attention of the abundant and people of material life for itself appearance instrument, it is more next
More people have used cosmetics.Cosmetics refer to smearing, sprinkling or other similar method, intersperse among appointing for human body surface
What position, such as skin, hair, refer to toenail, lips and teeth, to reach cleaning, maintenance, beauty, modification and change appearance, or amendment
Human scent, chemical industrial product or fine chemical product for the purpose of maintaining a good state.
Skin care item are exactly a kind of common cosmetics, and skin care item protect the skin-protection product of skin, skin care item were no longer
Remove the only thing risen of the rich.Nowadays skin care item have come into ordinary citizen house as the popular vehicles, it is mentioned to spirit, the image of people
Great effect is risen to.
Skin care item are provided convenience for people, but existing skin care item otherwise with anti-inflammatory effect or have anti-acne
Effect, the using effect for having both the skin care item of anti-inflammatory and anti-acne effect is unsatisfactory, and people are also in the research for carrying out this respect.
Summary of the invention
The purpose of the present invention is to provide a kind of anti-inflammatory anti-acne skin care item, to solve mentioned above in the background art ask
Topic.
To achieve the above object, the invention provides the following technical scheme:
A kind of anti-inflammatory anti-acne skin care item, the raw material including following parts by weight: 34-41 parts of water, 15-18.6 parts of glycerol, fourth two
22.4-27.8 parts of alcohol, -5 2.15-2.86 parts of myristoyl hexapeptide, -2 1.65-2.1 parts of acetyl group tetrapeptide, glucan 2.4-
2.9 parts, 4.2-5.9 parts of kuh-seng root extract, 7.6-8.8 parts of carbomer, 10.5-15.3 parts of Phenoxyethanol, Sensiva SC50
4.5-6.2 parts, 5.5-7.4 parts of methyl hydroxybenzoate, 6.4-7.7 parts of ethyl hydroxy benzoate and 3.6-6.8 parts of triethanolamine.
As a further solution of the present invention: glucan uses beta glucan.
As a further solution of the present invention: kuh-seng root extract is that radix sophorae is freeze-dried 10-15 minutes, is then used
Supercritical CO 2 extraction technology obtains.
As a further solution of the present invention: the anti-inflammatory anti-acne skin care item, the raw material including following parts by weight: water
37.2-41 parts, 16.5-18.6 parts of glycerol, 24.7-27.8 parts of butanediol, -5 2.32-2.86 parts of myristoyl hexapeptide, acetyl group
- 2 1.87-2.1 parts of tetrapeptide, 2.56-2.9 parts of glucan, 4.7-5.9 parts of kuh-seng root extract, 8.14-8.8 parts of carbomer, benzene
12.3-15.3 parts of oxyethanol, 5.28-6.2 parts of Sensiva SC50,6.2-7.4 parts of methyl hydroxybenzoate, 6.86-7.7 parts of ethyl hydroxy benzoate
With 4.5-6.8 parts of triethanolamine.
As a further solution of the present invention: the anti-inflammatory anti-acne skin care item, the raw material including following parts by weight: water 39.6
Part, 17.2 parts of glycerol, 26.3 parts of butanediol, -5 2.65 parts of myristoyl hexapeptide, 1.94 parts of acetyl group tetrapeptide -2, glucan
2.83 parts, 5.52 parts of kuh-seng root extract, 8.49 parts of carbomer, 14.7 parts of Phenoxyethanol, 5.85 parts of Sensiva SC50, oxybenzene
7.13 parts of methyl esters, 7.43 parts of ethyl hydroxy benzoate and 5.8 parts of triethanolamine.
The preparation method of the anti-inflammatory anti-acne skin care item, the specific steps are as follows: mix raw material and at 25-36 degrees Celsius
Lower moderate-speed mixer 20-35 minutes stands 2-3 hours then homogeneous 80-95 minutes in homogenizer to get finished product is arrived.
As a further solution of the present invention: the revolving speed of moderate-speed mixer is 330-450rpm, and the homogenizing temperature of homogenizer is
52-60 degrees Celsius, the homogeneous speed of homogenizer is 960-1050rpm.
Compared with prior art, the beneficial effects of the present invention are: this product raw material sources are extensive, preparation process is simple, leads to
It crosses and is used cooperatively various raw materials, the finished product of preparation has both the effect of good anti-inflammatory and anti-acne, and the use that can satisfy people needs
It asks, there is positive social benefit.
Specific embodiment
The technical solution of the patent is explained in further detail With reference to embodiment.
Embodiment 1
A kind of anti-inflammatory anti-acne skin care item, the raw material including following parts by weight: 34 parts of water, 15 parts of glycerol, 22.4 parts of butanediol,
- 5 2.15 parts of myristoyl hexapeptide, 1.65 parts of acetyl group tetrapeptide -2,2.4 parts of glucan, 4.2 parts of kuh-seng root extract, card wave
7.6 parts of nurse, 10.5 parts of Phenoxyethanol, 4.5 parts of Sensiva SC50,5.5 parts of methyl hydroxybenzoate, 6.4 parts of ethyl hydroxy benzoate and three ethyl alcohol
3.6 parts of amine.Kuh-seng root extract is that radix sophorae is freeze-dried 12 minutes, is then obtained using supercritical CO 2 extraction technology
It arrives.
The preparation method of the anti-inflammatory anti-acne skin care item, the specific steps are as follows: mix raw material and under 28 degrees Celsius
Moderate-speed mixer 25 minutes, then homogeneous 88 minutes in homogenizer, stood 2.5 hours to get finished product is arrived.
Embodiment 2
A kind of anti-inflammatory anti-acne skin care item, the raw material including following parts by weight: 37.2 parts of water, 16.5 parts of glycerol, butanediol
24.7 parts, -5 2.32 parts of myristoyl hexapeptide, 1.87 parts of acetyl group tetrapeptide -2,2.56 parts of glucan, kuh-seng root extract 4.7
Part, 8.14 parts of carbomer, 12.3 parts of Phenoxyethanol, 5.28 parts of Sensiva SC50,6.2 parts of methyl hydroxybenzoate, ethyl hydroxy benzoate 6.86
Part and 4.5 parts of triethanolamine.Glucan uses beta glucan.
The preparation method of the anti-inflammatory anti-acne skin care item, the specific steps are as follows: mix raw material and under 32 degrees Celsius
The revolving speed of hundred million 375rpm stirs 26 minutes, and then homogeneous 86 minutes in homogenizer, the homogenizing temperature of homogenizer are 57 degrees Celsius,
The homogeneous speed of homogenizer is 990rpm, stands 2 hours to get finished product is arrived.
Embodiment 3
A kind of anti-inflammatory anti-acne skin care item, the raw material including following parts by weight: 39.6 parts of water, 17.2 parts of glycerol, butanediol
26.3 parts, -5 2.65 parts of myristoyl hexapeptide, 1.94 parts of acetyl group tetrapeptide -2,2.83 parts of glucan, kuh-seng root extract
5.52 parts, 8.49 parts of carbomer, 14.7 parts of Phenoxyethanol, 5.85 parts of Sensiva SC50,7.13 parts of methyl hydroxybenzoate, ethyl hydroxy benzoate
7.43 parts and 5.8 parts of triethanolamine.Glucan uses beta glucan.Kuh-seng root extract is that radix sophorae is freeze-dried 14 minutes,
Then it is obtained using supercritical CO 2 extraction technology.
The preparation method of the anti-inflammatory anti-acne skin care item, the specific steps are as follows: mix raw material and under 26 degrees Celsius
It is stirred 33 minutes with the revolving speed of 420rpm, then homogeneous 92 minutes in homogenizer, the homogenizing temperature of homogenizer are 57 degrees Celsius,
The homogeneous speed of homogenizer is 1050rpm, stands 3 hours to get finished product is arrived.
Embodiment 4
A kind of anti-inflammatory anti-acne skin care item, the raw material including following parts by weight: 41 parts of water, 18.6 parts of glycerol, butanediol 27.8
Part, -5 2.86 parts of myristoyl hexapeptide, 2.1 parts of acetyl group tetrapeptide -2,2.9 parts of glucan, 5.9 parts of kuh-seng root extract, card
8.8 parts of wave nurse, 15.3 parts of Phenoxyethanol, 6.2 parts of Sensiva SC50,7.4 parts of methyl hydroxybenzoate, 7.7 parts of ethyl hydroxy benzoate and three second
6.8 parts of hydramine.Kuh-seng root extract is that radix sophorae is freeze-dried 15 minutes, is then obtained using supercritical CO 2 extraction technology
It arrives.
The preparation method of the anti-inflammatory anti-acne skin care item, the specific steps are as follows: mix raw material and under 35 degrees Celsius
Moderate-speed mixer 32 minutes, then homogeneous 86 minutes in homogenizer, stood 3 hours to get finished product is arrived.
Comparative example
As a comparison case using existing skin care item.
1000 volunteers are selected, stochastic averagina is divided into 5 groups, and the volunteer of 1-4 group uses the production of embodiment 1-4 respectively
Product, 5 groups of volunteer use the product of comparative example, and using to use after face cleaning, once in the morning and once at night, for 4 weeks, volunteer is to certainly
Oneself anti-inflammatory anti-acne effect marking, full marks are 10 points, score is higher to indicate that anti-inflammatory anti-acne effect is better, record every group and are averaged
Point, it the results are shown in Table 1.
Table 1
| 1 group | 2 groups | 3 groups | 4 groups | 5 groups | |
| Anti-acne group average mark | 9.18 | 9.25 | 9.39 | 9.15 | 7.83 |
| Anti-inflammatory group of average mark | 9.28 | 9.54 | 9.67 | 9.37 | 8.24 |
From table 1 it follows that 1-4 group is significantly larger than 5 groups in anti-inflammatory and anti-acne scoring, show production of the invention
Product are better than existing product on anti-inflammatory anti-acne effect.
The volunteer of 1-5 group finds no the adverse reactions such as allergy, itch in use.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims
Variation is included within the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiments being understood that.
Claims (7)
1. a kind of anti-inflammatory anti-acne skin care item, which is characterized in that the raw material including following parts by weight: 34-41 parts of water, glycerol 15-
18.6 parts, 22.4-27.8 parts of butanediol, -5 2.15-2.86 parts of myristoyl hexapeptide, -2 1.65-2.1 parts of acetyl group tetrapeptide,
2.4-2.9 parts of glucan, 4.2-5.9 parts of kuh-seng root extract, 7.6-8.8 parts of carbomer, 10.5-15.3 parts of Phenoxyethanol, second
4.5-6.2 parts of base hexyl glycerol, 5.5-7.4 parts of methyl hydroxybenzoate, 6.4-7.7 parts of ethyl hydroxy benzoate and 3.6-6.8 parts of triethanolamine.
2. anti-inflammatory anti-acne skin care item according to claim 1, which is characterized in that the glucan uses beta glucan.
3. anti-inflammatory anti-acne skin care item according to claim 1 or 2, which is characterized in that the kuh-seng root extract is kuh-seng
Root is freeze-dried 10-15 minutes, is then obtained using supercritical CO 2 extraction technology.
4. anti-inflammatory anti-acne skin care item according to claim 1, which is characterized in that the raw material including following parts by weight: water
37.2-41 parts, 16.5-18.6 parts of glycerol, 24.7-27.8 parts of butanediol, -5 2.32-2.86 parts of myristoyl hexapeptide, acetyl group
- 2 1.87-2.1 parts of tetrapeptide, 2.56-2.9 parts of glucan, 4.7-5.9 parts of kuh-seng root extract, 8.14-8.8 parts of carbomer, benzene
12.3-15.3 parts of oxyethanol, 5.28-6.2 parts of Sensiva SC50,6.2-7.4 parts of methyl hydroxybenzoate, 6.86-7.7 parts of ethyl hydroxy benzoate
With 4.5-6.8 parts of triethanolamine.
5. anti-inflammatory anti-acne skin care item according to claim 1, which is characterized in that the raw material including following parts by weight: water
39.6 parts, 17.2 parts of glycerol, 26.3 parts of butanediol, -5 2.65 parts of myristoyl hexapeptide, 1.94 parts of acetyl group tetrapeptide -2, Portugal it is poly-
Sugared 2.83 parts, 5.52 parts of kuh-seng root extract, 8.49 parts of carbomer, 14.7 parts of Phenoxyethanol, 5.85 parts of Sensiva SC50, hydroxyl
7.13 parts of benzene methyl, 7.43 parts of ethyl hydroxy benzoate and 5.8 parts of triethanolamine.
6. a kind of preparation method of anti-inflammatory anti-acne skin care item a method as claimed in any one of claims 1 to 5, which is characterized in that specific steps
It is as follows: raw material to be mixed and moderate-speed mixer 20-35 minutes lower at 25-36 degrees Celsius, then homogeneous 80-95 points in homogenizer
Clock stands 2-3 hours to get finished product is arrived.
7. the preparation method of anti-inflammatory anti-acne skin care item according to claim 6, which is characterized in that the moderate-speed mixer turns
Speed is 330-450rpm, and the homogenizing temperature of homogenizer is 52-60 degrees Celsius, and the homogeneous speed of homogenizer is 960-1050rpm.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811467560.2A CN109453050A (en) | 2018-12-03 | 2018-12-03 | A kind of anti-inflammatory anti-acne skin care item and preparation method thereof |
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| CN201811467560.2A CN109453050A (en) | 2018-12-03 | 2018-12-03 | A kind of anti-inflammatory anti-acne skin care item and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110115756A (en) * | 2019-05-23 | 2019-08-13 | 中山市粤美医疗生物科技有限公司 | A kind of Essence with antibacterial, anti-acne effect |
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| CN105310940A (en) * | 2015-11-25 | 2016-02-10 | 广州丹奇日用化工厂有限公司 | Acne removing composition, preparing method thereof and application thereof |
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| CN105310940A (en) * | 2015-11-25 | 2016-02-10 | 广州丹奇日用化工厂有限公司 | Acne removing composition, preparing method thereof and application thereof |
| CN107550775A (en) * | 2017-08-23 | 2018-01-09 | 杭州兰茜化妆品有限公司 | Natural plants anti-acne jelly and preparation method thereof |
| CN108042480A (en) * | 2018-01-12 | 2018-05-18 | 广州赛莱拉干细胞科技股份有限公司 | Mildy wash based on foreign Pseudanabaena sp extract |
| CN108186402A (en) * | 2018-03-14 | 2018-06-22 | 广州赛美化妆品有限公司 | A kind of Essence for skin-tightening smoothing wrinkle |
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| Title |
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| 国家药品监督管理局: "《化妆品安全技术规范》", 23 December 2015 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110115756A (en) * | 2019-05-23 | 2019-08-13 | 中山市粤美医疗生物科技有限公司 | A kind of Essence with antibacterial, anti-acne effect |
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Application publication date: 20190312 |