CN108186402A - A kind of Essence for skin-tightening smoothing wrinkle - Google Patents
A kind of Essence for skin-tightening smoothing wrinkle Download PDFInfo
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- CN108186402A CN108186402A CN201810209508.0A CN201810209508A CN108186402A CN 108186402 A CN108186402 A CN 108186402A CN 201810209508 A CN201810209508 A CN 201810209508A CN 108186402 A CN108186402 A CN 108186402A
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- skin
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- tightening
- essence
- smoothing wrinkle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of Essence for skin-tightening smoothing wrinkle, including following component in parts by weight：28 parts of moisturizer, 25 parts of chelating agent, 5 10 parts of elastin laminin, 37 parts of butanediol, 60 80 parts of water, 12 parts of surfactant, 0.1 0.3 parts of preservative.The present invention proposes a kind of Essence for skin-tightening smoothing wrinkle, and several functions component is compounded, and can effectively complete the deep layer nursing of skin, accelerate the metabolism of skin, repair impaired and keratinization skin, restore and keep the elasticity of skin；Product produced by the present invention has effects that moisturizing, smoothing wrinkle and restores skin elasticity, and high efficiency is up to 96.6%.
Description
Technical field
The present invention relates to technical field of skin care more particularly to a kind of Essences and its system for skin-tightening smoothing wrinkle
Preparation Method.
Background technology
Wrinkle refers to that skin is influenced by external environment, forms free free radical, and free radical destroys normal cell membrane tissue
Interior collagen, active material, oxidative cell and the small microgroove, the wrinkle that are formed.The form of skin aging is mainly that nature declines
(i.e. endogenous aging) and light aging (i.e. exogenous aging) always, naturally-aged is mainly caused by body inherent cause, is limited to complete
Body position, hence it is evident that be characterized as wrinkle and relaxation, and phenomena such as pigmentation occur.Light aging is mainly ultraviolet damage accumulation institute
The skin aging of cause is that naturally-aged and ultraviolet light irradiation are coefficient as a result, being limited to skin exposure portion.In addition, for
For most of women, During Pregnancy also results in the increase of skin of abdomen wrinkle, and also some women are because of inappropriate weight-reducing
The phenomenon that mode, quick weight-lossing causes skin to relax.
What is occurred currently on the market is many for skin wrinkle, the products to compact, but its less effective, and price compared with
It is expensive；Also some have side effect using rear to skin；Also some easily generates dependence, once it stops using, it is easy to it rebounds.
Invention content
Technical problems based on background technology, the present invention propose a kind of Essence for skin-tightening smoothing wrinkle,
Containing there are many for.
A kind of Essence for skin-tightening smoothing wrinkle, including following component in parts by weight：2-8 parts of moisturizer,
2-5 parts of chelating agent, 5-10 parts of elastin laminin, 3-7 parts of butanediol, 60-80 parts of water, 1-2 parts of surfactant, preservative 0.1-
0.3 part.
Preferably, the moisturizer is Sodium Hyaluronate.
Preferably, the chelating agent is beta glucan.
Preferably, the surfactant is palmityl glycine.
Preferably, the preservative is Phenoxyethanol.
Preferably, -2 3-8 parts of acetyl group tetrapeptide is further included.
A kind of preparation method of Essence for skin-tightening smoothing wrinkle, method and step are as follows：
S1：Water and butanediol are heated to 80-85 DEG C, moisturizer, chelating agent and elastin laminin is then added in, stirs evenly
Homogeneous 2-4min afterwards；
S2：Then surfactant and acetyl group tetrapeptide -2 are added in, 10-15min is kept the temperature after stirring evenly；
S3：It cools to after 35-40 DEG C, adds in preservative, stir evenly to obtain the final product.
Further, the mixing speed in described S1, S2, S3 is 300-500rpm.
A kind of shin moisturizer proposed by the present invention is applied to the compacting of skin, smoothing wrinkle.
The effect of key component in the present invention：
Sodium-salt form of the Sodium Hyaluronate for hyaluronic acid, the hyaluronic acid ingredient containing large, medium and small different molecular weight；
Aqueous solution of sodium hyaluronate has stronger viscoelasticity and lubricity, is applied to skin surface, macromolecular hyaluronic acid can form one
Layer moisturizing ventilated membrane keeps skin moisturizing glossy while can kill bacterium and obstruct the intrusion of external dust and ultraviolet light；Small point
Sub- hyaluronic acid can penetrate into skin corium, promote blood microcirculation, accelerate cytothesis, be conducive to suction of the skin to nutriment
It receives, plays the crease-resistant health-care effect of beauty.
Beta glucan belongs to one kind of polysaccharide, is present in the substances such as mushroom, cereal, is derived from natural raw material, nothing
It is toxicity, nonirritant, it can be with strengthen immunity；Skin care item containing beta glucan ingredient can adjust excess grease, strengthen skin
Skin function maintains skin nutrition balanced.Beta glucan can help to update and repair nervous skin, effectively reduce wrinkle of skin,
Improve the moisture retention of skin and compact smoothness, promote the healing and regeneration of scar, can be widely used in anti crease and anti senile old product,
Sun-proof and after-sun restorative product.
Elastin laminin is the main component of elastomer in rawhide tissue, the elasticity and flexibility of skin is decide, to light
Skin physiology ageing process caused by the chemical factors such as line, having prevents aging and promotes regenerated effect, in skin care item
Addition elastin laminin can effectively inhibit the phenomenon that the agings such as relaxation, wrinkle occurs in skin.
Acetyl group tetrapeptide -2 is a kind of active peptides containing 4 amino acid, has certain adjusting body's immunity
Effect, can enhance cutaneous immunisation phylactic power defensive power；The natural cause that collagen level and elastomer is maintained correctly to assemble can be enhanced,
Promoting the combination of cell and extracellular matrix, confrontation leads to the detrimental effect that skin firmness and adhesion strength are lost, so as to improve
Skin；It is mainly shown as the increase of epidermal thickness and the reparation of epidermal skin unity and coherence in writing.Acetyl group tetrapeptide -2 is mainly applied
Have：Anti-aging, anti-wrinkle product, medicine adornment product, striae of pregnancy eliminate product etc..
Application method：
This product is taken uniformly to be applied to the position improved required for abdomen, thigh, arm, back, neck skin etc., massages number
Minute wraps up in preservative film to after fully absorbing 10-20 minutes, removes.
Compared with prior art, the device have the advantages that being：
The present invention proposes a kind of Essence for skin-tightening smoothing wrinkle, several functions component is compounded, energy
The effective deep layer nursing for completing skin, accelerates the metabolism of skin, repairs impaired and keratinization skin, restore and keep
The elasticity of skin；Product produced by the present invention has effects that moisturizing, smoothing wrinkle and restores skin elasticity, and high efficiency reaches
96.6%.
Specific embodiment
The present invention is made with reference to specific embodiment further to explain.
Embodiment 1
A kind of Essence for skin-tightening smoothing wrinkle, including following component in parts by weight：Sodium Hyaluronate 2
Part, 2 parts of beta glucan, 5 parts of elastin laminin, 3 parts of acetyl group tetrapeptide -2,3 parts of butanediol, 60 parts of water, 1 part of palmityl glycine,
0.1 part of Phenoxyethanol.
A kind of preparation method of Essence for skin-tightening smoothing wrinkle, method and step are as follows：
S1：Water and butanediol are heated to 80 DEG C, then add in Sodium Hyaluronate, beta glucan and elastin laminin, stirring
Speed is 300rpm, stirs evenly rear homogeneous 4min；
S2：Then it adds in palmityl glycine and acetyl group tetrapeptide -2, mixing speed 300rpm is kept the temperature after stirring evenly
10min；
S3：It cools to after 35 DEG C, adds in Phenoxyethanol, mixing speed 500rpm is stirred evenly to obtain the final product.
Embodiment 2
A kind of Essence for skin-tightening smoothing wrinkle, including following component in parts by weight：Sodium Hyaluronate 8
Part, 5 parts of beta glucan, 10 parts of elastin laminin, 8 parts of acetyl group tetrapeptide -2,7 parts of butanediol, 80 parts of water, palmityl glycine 2
Part, 0.3 part of Phenoxyethanol.
A kind of preparation method of Essence for skin-tightening smoothing wrinkle, method and step are as follows：
S1：Water and butanediol are heated to 85 DEG C, then add in Sodium Hyaluronate, beta glucan and elastin laminin, stirring
Speed is 500rpm, stirs evenly rear homogeneous 2min；
S2：Then it adds in palmityl glycine and acetyl group tetrapeptide -2, mixing speed 500rpm is kept the temperature after stirring evenly
15min；
S3：It cools to after 40 DEG C, adds in Phenoxyethanol, mixing speed 300rpm is stirred evenly to obtain the final product.
Embodiment 3
A kind of Essence for skin-tightening smoothing wrinkle, including following component in parts by weight：Sodium Hyaluronate 5
Part, 3 parts of beta glucan, 8 parts of elastin laminin, 5 parts of acetyl group tetrapeptide -2,4 parts of butanediol, 70 parts of water, palmityl glycine 1.5
Part, 0.2 part of Phenoxyethanol.
A kind of preparation method of Essence for skin-tightening smoothing wrinkle, method and step are as follows：
S1：Water and butanediol are heated to 83 DEG C, then add in Sodium Hyaluronate, beta glucan and elastin laminin, stirring
Speed is 400rpm, stirs evenly rear homogeneous 3min；
S2：Then it adds in palmityl glycine and acetyl group tetrapeptide -2, mixing speed 400rpm is kept the temperature after stirring evenly
13min；
S3：It cools to after 38 DEG C, adds in Phenoxyethanol, mixing speed 400rpm is stirred evenly to obtain the final product.
Embodiment 4
A kind of Essence for skin-tightening smoothing wrinkle, including following component in parts by weight：Sodium Hyaluronate 6
Part, 2 parts of beta glucan, 6 parts of elastin laminin, 7 parts of acetyl group tetrapeptide -2,5 parts of butanediol, 65 parts of water, palmityl glycine 1.5
Part, 0.2 part of Phenoxyethanol.
A kind of preparation method of Essence for skin-tightening smoothing wrinkle, method and step are as follows：
S1：Water and butanediol are heated to 81 DEG C, then add in Sodium Hyaluronate, beta glucan and elastin laminin, stirring
Speed is 400rpm, stirs evenly rear homogeneous 3min；
S2：Then it adds in palmityl glycine and acetyl group tetrapeptide -2, mixing speed 350rpm is kept the temperature after stirring evenly
12min；
S3：It cools to after 36 DEG C, adds in Phenoxyethanol, mixing speed 400rpm is stirred evenly to obtain the final product.
Embodiment 5
A kind of Essence for skin-tightening smoothing wrinkle, including following component in parts by weight：Sodium Hyaluronate 3
Part, 4 parts of beta glucan, 7 parts of elastin laminin, 4 parts of acetyl group tetrapeptide -2,6 parts of butanediol, 75 parts of water, palmityl glycine 1.5
Part, 0.2 part of Phenoxyethanol.
A kind of preparation method of Essence for skin-tightening smoothing wrinkle, method and step are as follows：
S1：Water and butanediol are heated to 83 DEG C, then add in Sodium Hyaluronate, beta glucan and elastin laminin, stirring
Speed is 400rpm, stirs evenly rear homogeneous 4min；
S2：Then it adds in palmityl glycine and acetyl group tetrapeptide -2, mixing speed 450rpm is kept the temperature after stirring evenly
13min；
S3：It cools to after 39 DEG C, adds in Phenoxyethanol, mixing speed 400rpm is stirred evenly to obtain the final product.
Properties of product are tested
First, hygienic chemistry index：With reference to《Cosmetics safety technical specification》(version in 2015) Physico-chemical tests method, is as a result shown in
Table 1.
1 hygienic chemistry testing result of table
| Inspection project | Embodiment 1-5 |
| Mercury | ≤1mg/kg |
| Arsenic | ≤2mg/kg |
| Lead | ≤10mg/kg |
| Cadmium | ≤5mg/kg |
| Methanol | ≤2000mg/kg |
| Dioxane | ≤30mg/kg |
2nd, microbiological indicator：With reference to《Cosmetics safety technical specification》(version in 2015) microorganism detection method, is as a result shown in
Table 2.
2 microorganism detection result of table
| Inspection project | Embodiment 1-5 |
| Total plate count | ≤1000CFU/g |
| Yeast and mold sum | ≤100CFU/g |
| Heat-resisting coliform | It does not detect |
| Staphylococcus aureus | It does not detect |
| Pseudomonas aeruginosa | It does not detect |
3rd, skin irritation test
1st, subjects：Healthy adult rabbit 50 is chosen, is divided into 5 groups, every group 10, every rabbit back is selected at 2
Shaving 9cm2。
2nd, test method：The shin moisturizer implemented obtained by 1-5 is applied to respectively at the shaving of 5 groups of rabbit, is smeared for every eight hours
Once, observation for 24 hours, 48h and 72h smear the situation at position.
3rd, result of the test：50 tested rabbit do not occur the local stimulations such as erythema, oedema reaction, illustrate the present invention
Shin moisturizer obtained is safe and non-stimulating, without any adverse reactions.
4th, clinical test
1st, object is tried out：
(1) first group：118 people of women trier, age 25-55 Sui, for abdomen skin；
(2) second groups：137 people of women trier, age 25-55 Sui, for thigh skin；
(3) third group：121 people of women trier, age 30-55 Sui, for neck skin.
2nd, application method：This product is taken uniformly to be applied to the skin part for needing to improve, massages several minutes to after fully absorbing
It wraps up in preservative film 10-20 minutes, removes, after being used continuously 3 months, pay a return visit trial state.
3rd, criterion：It is effective：Wrinkle of skin is reduced, and skin smoothness and degree of compacting increase；In vain：Skin changes without any
It is kind.
4th, result on trial：It is shown in Table 3.
3 clinical test results of table
| Group | Number | It is effective | In vain | It is efficient |
| First group | 118 | 114 | 4 | 96.6% |
| Second group | 137 | 132 | 5 | 96.4% |
| Third group | 121 | 114 | 7 | 94.2% |
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (9)
1. a kind of Essence for skin-tightening smoothing wrinkle, which is characterized in that including following component in parts by weight：Moisturizing
2-8 parts of agent, 2-5 parts of chelating agent, 5-10 parts of elastin laminin, 3-7 parts of butanediol, 60-80 parts of water, 1-2 parts of surfactant, anti-corrosion
0.1-0.3 parts of agent.
2. a kind of Essence for skin-tightening smoothing wrinkle according to claim 1, which is characterized in that the moisturizer is
Sodium Hyaluronate.
3. a kind of Essence for skin-tightening smoothing wrinkle according to claim 1, which is characterized in that the chelating agent is
Beta glucan.
A kind of 4. Essence for skin-tightening smoothing wrinkle according to claim 1, which is characterized in that the surface-active
Agent is palmityl glycine.
5. a kind of Essence for skin-tightening smoothing wrinkle according to claim 1, which is characterized in that the preservative is
Phenoxyethanol.
6. a kind of Essence for skin-tightening smoothing wrinkle according to claim 1, which is characterized in that further include acetyl group
- 2 3-8 parts of tetrapeptide.
A kind of 7. preparation method of Essence for skin-tightening smoothing wrinkle according to claim 6, which is characterized in that side
Method step is as follows：
S1：Water and butanediol are heated to 80-85 DEG C, then add in moisturizer, chelating agent and elastin laminin, after stirring evenly
Matter 2-4min；
S2：Then surfactant and acetyl group tetrapeptide -2 are added in, 10-15min is kept the temperature after stirring evenly；
S3：It cools to after 35-40 DEG C, adds in preservative, stir evenly to obtain the final product.
A kind of 8. preparation method of Essence for skin-tightening smoothing wrinkle according to claim 7, which is characterized in that institute
It is 300-500rpm to state the mixing speed in S1, S2, S3.
9. shin moisturizer according to obtained by claim any one of 1-6 is applied to the compacting of skin, smoothing wrinkle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810209508.0A CN108186402A (en) | 2018-03-14 | 2018-03-14 | A kind of Essence for skin-tightening smoothing wrinkle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810209508.0A CN108186402A (en) | 2018-03-14 | 2018-03-14 | A kind of Essence for skin-tightening smoothing wrinkle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108186402A true CN108186402A (en) | 2018-06-22 |
Family
ID=62595775
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| CN201810209508.0A Pending CN108186402A (en) | 2018-03-14 | 2018-03-14 | A kind of Essence for skin-tightening smoothing wrinkle |
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Cited By (3)
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| CN109316377A (en) * | 2018-10-11 | 2019-02-12 | 西安医学院 | A kind of compound Essence and preparation method containing fusion protein |
| CN109453050A (en) * | 2018-12-03 | 2019-03-12 | 杭州恩格生物医疗科技有限公司 | A kind of anti-inflammatory anti-acne skin care item and preparation method thereof |
| CN117137822A (en) * | 2023-10-31 | 2023-12-01 | 杭州湃肽生化科技有限公司 | Anti-aging composition and application thereof |
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| CN117137822A (en) * | 2023-10-31 | 2023-12-01 | 杭州湃肽生化科技有限公司 | Anti-aging composition and application thereof |
| CN117137822B (en) * | 2023-10-31 | 2024-02-13 | 杭州湃肽生化科技有限公司 | Anti-aging composition and application thereof |
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