CN109312342A - 靶向核酸偶联物组合物 - Google Patents

靶向核酸偶联物组合物 Download PDF

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Publication number
CN109312342A
CN109312342A CN201780034659.0A CN201780034659A CN109312342A CN 109312342 A CN109312342 A CN 109312342A CN 201780034659 A CN201780034659 A CN 201780034659A CN 109312342 A CN109312342 A CN 109312342A
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compound
salt
group
alkyl
hydrocarbon chain
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Chinese (zh)
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詹姆斯·海斯
理查德·J·霍兰德
艾伦·D·马丁
马克·伍德
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Abt J Biopharmaceutical Co
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Abt J Biopharmaceutical Co
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    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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CN201780034659.0A 2016-04-11 2017-04-11 靶向核酸偶联物组合物 Pending CN109312342A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662321034P 2016-04-11 2016-04-11
US62/321,034 2016-04-11
US201662417156P 2016-11-03 2016-11-03
US62/417,156 2016-11-03
US201662438310P 2016-12-22 2016-12-22
US62/438,310 2016-12-22
PCT/CA2017/050447 WO2017177326A1 (en) 2016-04-11 2017-04-11 Targeted nucleic acid conjugate compositions

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CN109312342A true CN109312342A (zh) 2019-02-05

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CN114206389A (zh) * 2019-03-21 2022-03-18 有丝分裂疗法有限责任公司 用于靶向递送治疗剂的多价配体簇
CN116546989A (zh) * 2020-10-09 2023-08-04 阿达尔克斯制药有限公司 N-乙酰半乳糖胺(GalNAc)来源的化合物和寡核苷酸
CN116472063A (zh) * 2020-11-06 2023-07-21 阿布特斯生物制药公司 包含经修饰的siRNA的靶向性偶联物
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