CN109293551A - 与粒细胞集落刺激因子受体相关的方法和组合物 - Google Patents

与粒细胞集落刺激因子受体相关的方法和组合物 Download PDF

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Publication number
CN109293551A
CN109293551A CN201810783680.7A CN201810783680A CN109293551A CN 109293551 A CN109293551 A CN 109293551A CN 201810783680 A CN201810783680 A CN 201810783680A CN 109293551 A CN109293551 A CN 109293551A
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Chinese (zh)
Inventor
比基安·派德拉姆
史蒂文·L·罗奇
维吉尼亚·H·格兰特
智林
安德鲁·R·赫德森
詹森·C·皮肯斯
沈宜兴
里诺·J·瓦尔迪兹
基思·马斯克
C·阿尔健·万厄费伦
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Ligand Pharmaceuticals Inc
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Ligand Pharmaceuticals Inc
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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CN201810783680.7A 2011-11-14 2012-11-12 与粒细胞集落刺激因子受体相关的方法和组合物 Pending CN109293551A (zh)

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US201161559660P 2011-11-14 2011-11-14
US61/559,660 2011-11-14
US201161561510P 2011-11-18 2011-11-18
US61/561,510 2011-11-18
CN201280064120.7A CN104039761A (zh) 2011-11-14 2012-11-12 与粒细胞集落刺激因子受体相关的方法和组合物

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US (4) US9492430B2 (https=)
EP (1) EP2780322B1 (https=)
JP (3) JP6072058B2 (https=)
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