MX2008011666A - Sintesis de compuestos que modulan la actividad de la trombopoyetina. - Google Patents
Sintesis de compuestos que modulan la actividad de la trombopoyetina.Info
- Publication number
- MX2008011666A MX2008011666A MX2008011666A MX2008011666A MX2008011666A MX 2008011666 A MX2008011666 A MX 2008011666A MX 2008011666 A MX2008011666 A MX 2008011666A MX 2008011666 A MX2008011666 A MX 2008011666A MX 2008011666 A MX2008011666 A MX 2008011666A
- Authority
- MX
- Mexico
- Prior art keywords
- synthesis
- modulating compounds
- activity modulating
- thrombopoietin activity
- thrombopoietin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Se describen en la presente varios métodos para sintetizar compuestos que modulan la actividad de la trombopoyetina. También se describen intermediarios útiles para la preparación de estos compuestos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78242606P | 2006-03-15 | 2006-03-15 | |
PCT/US2007/006547 WO2007106564A2 (en) | 2006-03-15 | 2007-03-14 | Synthesis of thrombopoietin activity modulating compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2008011666A true MX2008011666A (es) | 2008-10-17 |
Family
ID=38308644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008011666A MX2008011666A (es) | 2006-03-15 | 2007-03-14 | Sintesis de compuestos que modulan la actividad de la trombopoyetina. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20100063301A1 (es) |
EP (1) | EP2001845A2 (es) |
JP (1) | JP2009530297A (es) |
KR (1) | KR20090004953A (es) |
CN (1) | CN101437792A (es) |
AU (1) | AU2007225115A1 (es) |
BR (1) | BRPI0709286A2 (es) |
CA (1) | CA2646232A1 (es) |
MX (1) | MX2008011666A (es) |
WO (1) | WO2007106564A2 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005118551A2 (en) | 2004-05-28 | 2005-12-15 | Ligand Pharmaceuticals Inc. | Thrombopoietin activity modulating compounds and methods |
US20110129550A1 (en) | 2007-02-16 | 2011-06-02 | Connie Erickson-Miller | Cancer treatment method |
UY30915A1 (es) | 2007-02-16 | 2008-09-02 | Smithkline Beecham Corp | Método de tratamiento de canceres |
CA2709224C (en) | 2007-10-09 | 2015-06-23 | The Trustees Of The University Of Pennsylvania | Thrombopoietin receptor agonist (tpora) kills acute human myeloid leukemia cells |
US8476249B2 (en) | 2009-05-07 | 2013-07-02 | Glaxosmithkline Llc | Method of treating thrombocytopenia |
JP6072058B2 (ja) * | 2011-11-14 | 2017-02-01 | リガンド・ファーマシューティカルズ・インコーポレイテッド | 顆粒球コロニー刺激因子受容体と結合する方法および組成物 |
US9962370B2 (en) | 2013-03-15 | 2018-05-08 | Ligand Pharmaceuticals Incorporated | Methods of treatment associated with the granulocyte colony-stimulating factor receptor |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3148192A (en) * | 1961-06-27 | 1964-09-08 | Roussel Uclaf | Halogenated 20alpha-yohimbane compounds |
GB8816944D0 (en) * | 1988-07-15 | 1988-08-17 | Sobio Lab | Compounds |
WO2003011287A1 (en) * | 2001-08-03 | 2003-02-13 | Vertex Pharmaceuticals Incorporated | Pyrazolon derivatives as inhibitors of gsk-3 |
JP4562523B2 (ja) * | 2002-06-06 | 2010-10-13 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | トロンボポエチン疑似体 |
BRPI0511057A (pt) * | 2004-05-12 | 2007-11-27 | Bayer Cropscience Gmbh | regulação de crescimento da planta |
-
2007
- 2007-03-14 CA CA002646232A patent/CA2646232A1/en not_active Abandoned
- 2007-03-14 EP EP07753193A patent/EP2001845A2/en not_active Withdrawn
- 2007-03-14 KR KR1020087024952A patent/KR20090004953A/ko not_active Application Discontinuation
- 2007-03-14 US US12/282,876 patent/US20100063301A1/en not_active Abandoned
- 2007-03-14 MX MX2008011666A patent/MX2008011666A/es not_active Application Discontinuation
- 2007-03-14 AU AU2007225115A patent/AU2007225115A1/en not_active Abandoned
- 2007-03-14 JP JP2009500487A patent/JP2009530297A/ja not_active Withdrawn
- 2007-03-14 BR BRPI0709286-5A patent/BRPI0709286A2/pt not_active IP Right Cessation
- 2007-03-14 CN CNA2007800162343A patent/CN101437792A/zh active Pending
- 2007-03-14 WO PCT/US2007/006547 patent/WO2007106564A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
US20100063301A1 (en) | 2010-03-11 |
JP2009530297A (ja) | 2009-08-27 |
EP2001845A2 (en) | 2008-12-17 |
BRPI0709286A2 (pt) | 2011-07-05 |
AU2007225115A1 (en) | 2007-09-20 |
KR20090004953A (ko) | 2009-01-12 |
CA2646232A1 (en) | 2007-09-20 |
WO2007106564A3 (en) | 2008-02-14 |
CN101437792A (zh) | 2009-05-20 |
WO2007106564A2 (en) | 2007-09-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2010003599A (es) | Intermediarios y metodos para la sintesis de analogos de halicondrina b. | |
MY148253A (en) | Azaadamantane derivatives and methods of use | |
TW200640924A (en) | VEGF-R2 inhibitors and methods | |
NO20075643L (no) | Fremgangsmater for fremstilling av 3-cyano-kinoliner og derved fremstilte mellomprodukter | |
MX342683B (es) | Analogos de ciclopamina. | |
MX2007001127A (es) | Moduladores de pirrolo-piridina cinasa. | |
MX2008011666A (es) | Sintesis de compuestos que modulan la actividad de la trombopoyetina. | |
SG171617A1 (en) | Therapeutic compounds | |
TW200626068A (en) | Active compounds for seed treatment | |
UA94833C2 (en) | Substituted bicyclolactams | |
MX2010009752A (es) | Compuestos de oxadiazoantraceno para el tratamiento de diabetes. | |
EA201070256A1 (ru) | Способ и промежуточные соединения для получения ингибиторов интегразы | |
EA201000883A1 (ru) | Производные индолинона и способ их получения | |
AU2008303600A8 (en) | 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives | |
WO2007138282A3 (en) | Bi-aryl or aryl-heteroaryl substituted indoles | |
MY160392A (en) | Triptolide prodrugs | |
WO2008041140A3 (en) | Substituted aryl-indole compounds and their kynurenine/kynuramine-like metabolites as therapeutic agents | |
WO2012015681A3 (en) | Drug-ligand conjugates, synthesis thereof, and intermediates thereto | |
TW200728310A (en) | Process for the preparation of ferri-succinylcasein | |
WO2008053334A3 (en) | An improved process for preparing rosuvastatin calcium | |
TW200800986A (en) | Tetrahydroquinolines, synthesis thereof, and intermediates thereto | |
TW200738713A (en) | Diazepinoquinolines, synthesis thereof, and intermediates thereto | |
TN2009000536A1 (en) | Novel herbicides | |
EA201170721A1 (ru) | 3-аминоциклопентанкарбоксамиды в качестве модуляторов рецептора хемокина | |
MX2012006524A (es) | Proceso para la sintesis de compuestos intermedios de utilidad para preparar compuestos sustituidos de indazol y azaindol. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |