MX2007003377A - Agonistas del receptor de trombopoyetina. - Google Patents
Agonistas del receptor de trombopoyetina.Info
- Publication number
- MX2007003377A MX2007003377A MX2007003377A MX2007003377A MX2007003377A MX 2007003377 A MX2007003377 A MX 2007003377A MX 2007003377 A MX2007003377 A MX 2007003377A MX 2007003377 A MX2007003377 A MX 2007003377A MX 2007003377 A MX2007003377 A MX 2007003377A
- Authority
- MX
- Mexico
- Prior art keywords
- trombopoietin
- receptor agonists
- megakaryocytopoiesis
- thrombopoiesis
- promoters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Un compuesto de la Formula (Ver Formula I) util como promotor de la trombopoyesis y megacariocitopoyesis, donde A, B, D, E, W, X, Y, Z, R1 y R2 se definen como anteriormente.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61291104P | 2004-09-23 | 2004-09-23 | |
US69269105P | 2005-06-20 | 2005-06-20 | |
PCT/IB2005/002892 WO2006033005A2 (en) | 2004-09-23 | 2005-09-12 | Thrombopoietin receptor agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007003377A true MX2007003377A (es) | 2007-05-10 |
Family
ID=36090385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007003377A MX2007003377A (es) | 2004-09-23 | 2005-09-12 | Agonistas del receptor de trombopoyetina. |
Country Status (7)
Country | Link |
---|---|
US (1) | US20080076771A1 (es) |
EP (1) | EP1794156A2 (es) |
JP (1) | JP2008513434A (es) |
BR (1) | BRPI0515571A (es) |
CA (1) | CA2581657A1 (es) |
MX (1) | MX2007003377A (es) |
WO (1) | WO2006033005A2 (es) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ563866A (en) | 2005-05-09 | 2011-03-31 | Achillion Pharmaceuticals Inc | Thiazole compounds and methods of use |
BRPI0712862A2 (pt) * | 2006-06-08 | 2012-12-18 | Lilly Co Eli | carboxamidas substituìdas |
CA2687817A1 (en) | 2007-05-22 | 2008-12-04 | Achillion Pharmaceuticals, Inc. | Heteroaryl substituted thiazoles |
US8106209B2 (en) | 2008-06-06 | 2012-01-31 | Achillion Pharmaceuticals, Inc. | Substituted aminothiazole prodrugs of compounds with anti-HCV activity |
EP2303018B1 (en) * | 2008-06-19 | 2015-10-14 | Xcovery Holding Company LLC | Substituted pyridazine carboxamide compounds as kinase inhibitor compounds |
EP2419412A1 (en) * | 2009-04-13 | 2012-02-22 | Irm Llc | Compositions and methods for modulating retinol binding to retinol binding protein 4 (rbp4) |
US8680150B2 (en) | 2009-05-28 | 2014-03-25 | Ligand Pharmaceuticals, Inc. | Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors |
US8470820B2 (en) * | 2010-01-22 | 2013-06-25 | Hoffman-La Roche Inc. | Nitrogen-containing heteroaryl derivatives |
JP4944286B1 (ja) * | 2010-09-22 | 2012-05-30 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | シクロプロパン化合物 |
JP6072695B2 (ja) | 2010-11-03 | 2017-02-01 | ダウ アグロサイエンシィズ エルエルシー | 殺有害生物剤組成物およびこれに関連した方法 |
CN104010505B (zh) | 2011-10-26 | 2017-03-15 | 陶氏益农公司 | 杀虫组合物和与其相关的方法 |
WO2013074459A1 (en) | 2011-11-14 | 2013-05-23 | Ligand Pharmaceuticals, Inc. | Methods and compositions associated with the granulocyte colony-stimulating factor receptor |
KR20150013586A (ko) | 2012-04-27 | 2015-02-05 | 다우 아그로사이언시즈 엘엘씨 | 살충 조성물 및 그와 관련된 방법 |
US9708288B2 (en) | 2012-04-27 | 2017-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
UA115451C2 (uk) | 2012-10-02 | 2017-11-10 | Байєр Кропсайєнс Акцієнгезелльшафт | Гетероциклічні сполуки як пестициди |
US9962370B2 (en) | 2013-03-15 | 2018-05-08 | Ligand Pharmaceuticals Incorporated | Methods of treatment associated with the granulocyte colony-stimulating factor receptor |
JP2016535008A (ja) | 2013-10-17 | 2016-11-10 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除化合物の調製法 |
EP3057431A4 (en) | 2013-10-17 | 2017-04-05 | Dow AgroSciences LLC | Processes for the preparation of pesticidal compounds |
CN105636441B (zh) | 2013-10-17 | 2018-06-15 | 美国陶氏益农公司 | 制备杀虫化合物的方法 |
KR20160072155A (ko) | 2013-10-17 | 2016-06-22 | 다우 아그로사이언시즈 엘엘씨 | 살충성 화합물의 제조 방법 |
JP2016536296A (ja) | 2013-10-17 | 2016-11-24 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除性化合物の製造方法 |
MX2016004940A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Proceso para la preparacion de compuestos plaguicidas. |
MX2016004945A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Procesos para la preparacion de compuestos plaguicidas. |
CN105848480A (zh) | 2013-10-22 | 2016-08-10 | 美国陶氏益农公司 | 协同杀虫组合物和相关方法 |
MX2016005304A (es) | 2013-10-22 | 2017-03-01 | Dow Agrosciences Llc | Composiciones pesticidas sinergicas y metodos relacionados. |
AU2014340415B2 (en) | 2013-10-22 | 2017-07-06 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
AU2014340409B2 (en) | 2013-10-22 | 2017-09-07 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
EP3060048A4 (en) | 2013-10-22 | 2017-04-26 | Dow AgroSciences LLC | Pesticidal compositions and related methods |
EP3094183A4 (en) | 2013-10-22 | 2017-08-09 | Dow AgroSciences LLC | Synergistic pesticidal compositions and related methods |
RU2016119359A (ru) | 2013-10-22 | 2017-11-28 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Синергетические пестицидные композиции и связанные с ними способы |
CA2927215A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
JP2016534086A (ja) | 2013-10-22 | 2016-11-04 | ダウ アグロサイエンシィズ エルエルシー | 相乗的有害生物防除組成物および関連する方法 |
KR20160074637A (ko) | 2013-10-22 | 2016-06-28 | 다우 아그로사이언시즈 엘엘씨 | 살충 조성물 및 관련 방법 |
AR098088A1 (es) | 2013-10-22 | 2016-05-04 | Dow Agrosciences Llc | Composiciones plaguicidas sinérgicas y métodos relacionados |
AU2014340428B2 (en) | 2013-10-22 | 2017-06-29 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
MX2016005324A (es) | 2013-10-22 | 2016-08-12 | Dow Agrosciences Llc | Composiciones pesticidas y metodos relacionados. |
AU2014340437B2 (en) | 2013-10-22 | 2017-09-07 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
JP2016535026A (ja) | 2013-10-22 | 2016-11-10 | ダウ アグロサイエンシィズ エルエルシー | 相乗的有害生物防除組成物および関連する方法 |
RU2658995C2 (ru) | 2013-10-22 | 2018-06-26 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Пестицидные композиции и связанные с ними способы |
CN105682462A (zh) | 2013-10-22 | 2016-06-15 | 美国陶氏益农公司 | 杀虫组合物和与其相关的方法 |
CA2930712A1 (en) | 2013-11-14 | 2015-05-21 | Scynexis Inc. | Antiparasitic compounds |
WO2016018444A1 (en) | 2014-07-31 | 2016-02-04 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
CA2954747A1 (en) | 2014-07-31 | 2016-02-04 | Dow Agrosciences Lcc | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
CN106488909A (zh) | 2014-07-31 | 2017-03-08 | 美国陶氏益农公司 | 制备3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的方法 |
CN107074774A (zh) | 2014-08-19 | 2017-08-18 | 美国陶氏益农公司 | 制备3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的方法 |
US9085552B1 (en) | 2014-09-12 | 2015-07-21 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
AU2015336463B2 (en) | 2014-10-23 | 2020-06-18 | Eisai R&D Management Co., Ltd. | Compositions and methods for treating insomnia |
WO2017019772A1 (en) * | 2015-07-27 | 2017-02-02 | Sanford Burnham Prebys Medical Discovery Institute | Modulators of myocyte lipid accumulation and insulin resistance and methods of use thereof |
US10100033B2 (en) | 2016-12-29 | 2018-10-16 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
WO2018125817A1 (en) | 2016-12-29 | 2018-07-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
CU20210065A7 (es) | 2019-01-31 | 2022-04-07 | Pfizer | Compuestos de 3-carbonilamino-5-ciclopentil-1h-pirazol que tienen actividad inhibitoria en cdk2 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19929782A1 (de) * | 1999-06-29 | 2001-01-04 | Bayer Ag | 6-Carboxyphenyldihydropyridazinon-Derivate und ihre Verwendung |
CN1376150A (zh) * | 1999-07-26 | 2002-10-23 | 盐野义制药株式会社 | 具有血栓形成素受体拮抗作用的药物组合物 |
TWI284639B (en) * | 2000-01-24 | 2007-08-01 | Shionogi & Co | A compound having thrombopoietin receptor agonistic effect |
MXPA03006510A (es) * | 2001-01-26 | 2003-10-15 | Shionogi & Co | Compuestos halogenados que muestran agonismo del receptor de trombopoyetina. |
-
2005
- 2005-09-12 CA CA002581657A patent/CA2581657A1/en not_active Abandoned
- 2005-09-12 MX MX2007003377A patent/MX2007003377A/es unknown
- 2005-09-12 BR BRPI0515571-1A patent/BRPI0515571A/pt not_active Application Discontinuation
- 2005-09-12 JP JP2007531867A patent/JP2008513434A/ja active Pending
- 2005-09-12 US US11/575,680 patent/US20080076771A1/en not_active Abandoned
- 2005-09-12 EP EP05796020A patent/EP1794156A2/en not_active Withdrawn
- 2005-09-12 WO PCT/IB2005/002892 patent/WO2006033005A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
BRPI0515571A (pt) | 2008-07-29 |
CA2581657A1 (en) | 2006-03-30 |
JP2008513434A (ja) | 2008-05-01 |
US20080076771A1 (en) | 2008-03-27 |
EP1794156A2 (en) | 2007-06-13 |
WO2006033005A2 (en) | 2006-03-30 |
WO2006033005A3 (en) | 2007-01-25 |
WO2006033005A8 (en) | 2007-04-19 |
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