MX2007003377A - Agonistas del receptor de trombopoyetina. - Google Patents

Agonistas del receptor de trombopoyetina.

Info

Publication number
MX2007003377A
MX2007003377A MX2007003377A MX2007003377A MX2007003377A MX 2007003377 A MX2007003377 A MX 2007003377A MX 2007003377 A MX2007003377 A MX 2007003377A MX 2007003377 A MX2007003377 A MX 2007003377A MX 2007003377 A MX2007003377 A MX 2007003377A
Authority
MX
Mexico
Prior art keywords
trombopoietin
receptor agonists
megakaryocytopoiesis
thrombopoiesis
promoters
Prior art date
Application number
MX2007003377A
Other languages
English (en)
Inventor
Lawrence Alan Reiter
Robert Gerald Ii Linde
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MX2007003377A publication Critical patent/MX2007003377A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom
    • C07D473/34Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Un compuesto de la Formula (Ver Formula I) util como promotor de la trombopoyesis y megacariocitopoyesis, donde A, B, D, E, W, X, Y, Z, R1 y R2 se definen como anteriormente.
MX2007003377A 2004-09-23 2005-09-12 Agonistas del receptor de trombopoyetina. MX2007003377A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61291104P 2004-09-23 2004-09-23
US69269105P 2005-06-20 2005-06-20
PCT/IB2005/002892 WO2006033005A2 (en) 2004-09-23 2005-09-12 Thrombopoietin receptor agonists

Publications (1)

Publication Number Publication Date
MX2007003377A true MX2007003377A (es) 2007-05-10

Family

ID=36090385

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007003377A MX2007003377A (es) 2004-09-23 2005-09-12 Agonistas del receptor de trombopoyetina.

Country Status (7)

Country Link
US (1) US20080076771A1 (es)
EP (1) EP1794156A2 (es)
JP (1) JP2008513434A (es)
BR (1) BRPI0515571A (es)
CA (1) CA2581657A1 (es)
MX (1) MX2007003377A (es)
WO (1) WO2006033005A2 (es)

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US8106209B2 (en) 2008-06-06 2012-01-31 Achillion Pharmaceuticals, Inc. Substituted aminothiazole prodrugs of compounds with anti-HCV activity
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JP6072695B2 (ja) 2010-11-03 2017-02-01 ダウ アグロサイエンシィズ エルエルシー 殺有害生物剤組成物およびこれに関連した方法
CN104010505B (zh) 2011-10-26 2017-03-15 陶氏益农公司 杀虫组合物和与其相关的方法
WO2013074459A1 (en) 2011-11-14 2013-05-23 Ligand Pharmaceuticals, Inc. Methods and compositions associated with the granulocyte colony-stimulating factor receptor
KR20150013586A (ko) 2012-04-27 2015-02-05 다우 아그로사이언시즈 엘엘씨 살충 조성물 및 그와 관련된 방법
US9708288B2 (en) 2012-04-27 2017-07-18 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
US9282739B2 (en) 2012-04-27 2016-03-15 Dow Agrosciences Llc Pesticidal compositions and processes related thereto
UA115451C2 (uk) 2012-10-02 2017-11-10 Байєр Кропсайєнс Акцієнгезелльшафт Гетероциклічні сполуки як пестициди
US9962370B2 (en) 2013-03-15 2018-05-08 Ligand Pharmaceuticals Incorporated Methods of treatment associated with the granulocyte colony-stimulating factor receptor
JP2016535008A (ja) 2013-10-17 2016-11-10 ダウ アグロサイエンシィズ エルエルシー 有害生物防除化合物の調製法
EP3057431A4 (en) 2013-10-17 2017-04-05 Dow AgroSciences LLC Processes for the preparation of pesticidal compounds
CN105636441B (zh) 2013-10-17 2018-06-15 美国陶氏益农公司 制备杀虫化合物的方法
KR20160072155A (ko) 2013-10-17 2016-06-22 다우 아그로사이언시즈 엘엘씨 살충성 화합물의 제조 방법
JP2016536296A (ja) 2013-10-17 2016-11-24 ダウ アグロサイエンシィズ エルエルシー 有害生物防除性化合物の製造方法
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MX2016004945A (es) 2013-10-17 2016-06-28 Dow Agrosciences Llc Procesos para la preparacion de compuestos plaguicidas.
CN105848480A (zh) 2013-10-22 2016-08-10 美国陶氏益农公司 协同杀虫组合物和相关方法
MX2016005304A (es) 2013-10-22 2017-03-01 Dow Agrosciences Llc Composiciones pesticidas sinergicas y metodos relacionados.
AU2014340415B2 (en) 2013-10-22 2017-07-06 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
AU2014340409B2 (en) 2013-10-22 2017-09-07 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
EP3060048A4 (en) 2013-10-22 2017-04-26 Dow AgroSciences LLC Pesticidal compositions and related methods
EP3094183A4 (en) 2013-10-22 2017-08-09 Dow AgroSciences LLC Synergistic pesticidal compositions and related methods
RU2016119359A (ru) 2013-10-22 2017-11-28 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Синергетические пестицидные композиции и связанные с ними способы
CA2927215A1 (en) 2013-10-22 2015-04-30 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
JP2016534086A (ja) 2013-10-22 2016-11-04 ダウ アグロサイエンシィズ エルエルシー 相乗的有害生物防除組成物および関連する方法
KR20160074637A (ko) 2013-10-22 2016-06-28 다우 아그로사이언시즈 엘엘씨 살충 조성물 및 관련 방법
AR098088A1 (es) 2013-10-22 2016-05-04 Dow Agrosciences Llc Composiciones plaguicidas sinérgicas y métodos relacionados
AU2014340428B2 (en) 2013-10-22 2017-06-29 Dow Agrosciences Llc Pesticidal compositions and related methods
MX2016005324A (es) 2013-10-22 2016-08-12 Dow Agrosciences Llc Composiciones pesticidas y metodos relacionados.
AU2014340437B2 (en) 2013-10-22 2017-09-07 Dow Agrosciences Llc Synergistic pesticidal compositions and related methods
JP2016535026A (ja) 2013-10-22 2016-11-10 ダウ アグロサイエンシィズ エルエルシー 相乗的有害生物防除組成物および関連する方法
RU2658995C2 (ru) 2013-10-22 2018-06-26 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Пестицидные композиции и связанные с ними способы
CN105682462A (zh) 2013-10-22 2016-06-15 美国陶氏益农公司 杀虫组合物和与其相关的方法
CA2930712A1 (en) 2013-11-14 2015-05-21 Scynexis Inc. Antiparasitic compounds
WO2016018444A1 (en) 2014-07-31 2016-02-04 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
CA2954747A1 (en) 2014-07-31 2016-02-04 Dow Agrosciences Lcc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
CN106488909A (zh) 2014-07-31 2017-03-08 美国陶氏益农公司 制备3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的方法
CN107074774A (zh) 2014-08-19 2017-08-18 美国陶氏益农公司 制备3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的方法
US9085552B1 (en) 2014-09-12 2015-07-21 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine
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CU20210065A7 (es) 2019-01-31 2022-04-07 Pfizer Compuestos de 3-carbonilamino-5-ciclopentil-1h-pirazol que tienen actividad inhibitoria en cdk2

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DE19929782A1 (de) * 1999-06-29 2001-01-04 Bayer Ag 6-Carboxyphenyldihydropyridazinon-Derivate und ihre Verwendung
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Also Published As

Publication number Publication date
BRPI0515571A (pt) 2008-07-29
CA2581657A1 (en) 2006-03-30
JP2008513434A (ja) 2008-05-01
US20080076771A1 (en) 2008-03-27
EP1794156A2 (en) 2007-06-13
WO2006033005A2 (en) 2006-03-30
WO2006033005A3 (en) 2007-01-25
WO2006033005A8 (en) 2007-04-19

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