CN108887474A - A kind of compound preparation of resisting stress and preparation method thereof - Google Patents
A kind of compound preparation of resisting stress and preparation method thereof Download PDFInfo
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- CN108887474A CN108887474A CN201810610714.2A CN201810610714A CN108887474A CN 108887474 A CN108887474 A CN 108887474A CN 201810610714 A CN201810610714 A CN 201810610714A CN 108887474 A CN108887474 A CN 108887474A
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
Abstract
The invention belongs to feed additive fields, specifically disclose a kind of compound preparation and preparation method thereof of resisting stress.It is to be grouped as in terms of 100 parts by following groups by the sum of parts by weight：5-10 parts of vitamin C, 5-10 parts of taurine, 0.1-0.3 parts of vitamin K, 0.02-0.05 parts of chromium picolinate, 5-10 parts of fumaric acid, 10-20 parts of γ-aminobutyric acid, 2-6 parts of ammonium chloride, 0.5-1 parts of folic acid, 1-3 parts of chitosan oligosaccharide, 3-8 parts of gypsum powder, 5-10 parts of Shitake Mushroom P.E, 5-10 parts of glutinous rehmannia extract, 5-10 parts of Herba Plantaginis extract, 10-20 parts of capejasmine extract, DEXTROSE ANHYDROUS are supplemented to 100 parts.The above Drug combination, not only can nutrition enhancing, release stress, but also adjustable Abwehrkraft des Koepers, improve immunity etc., can prevent caused by a variety of causes stress and to reduce due to stress caused by a harm to the system, and be drug that noresidue has no drug resistance, safely and effectively.
Description
Technical field
The invention belongs to feed additive fields, and in particular to a kind of compound preparation of resisting stress and preparation method thereof.
Background technique
It stress refer to the summations that body reacts nonspecific response caused by extraneous or internal various very stimulations,
It is reaction of the animal to external stimulus in body or challenge.Generate stress the reason of have it is following several：1. feeding management factor；2. ring
Border factor；3. microorganism infection, bacterium, virus, helminth, mycoplasma and Chlamydia etc.；4. other human factors.Stress danger
Evil has：Production performance reduction, hypoimmunity, reproductive capacity is low, livestock products quality reduces, demand increases and nutritional deficiency.
With the height intensivization development of animal husbandry, livestock and poultry stress syndrome incidence constantly rise, livestock and poultry stress
Harm just become increasingly conspicuous and have become one of the most active factor for hindering animal husbandry development, because due to caused that people's is extensive
Concern.
Summary of the invention
The purpose of the present invention is to provide compound preparations of a kind of resisting stress and preparation method thereof.
To achieve the above object, the technical solution adopted by the present invention is as follows：
A kind of compound preparation of resisting stress is to be grouped as in terms of 100 parts by following groups by the sum of parts by weight：
5-10 parts of vitamin C, 0.1-0.3 parts of vitamin K, 0.02-0.05 parts of chromium picolinate, prolongs recklessly 5-10 parts of taurine
5-10 parts of carboxylic acid, 10-20 parts of γ-aminobutyric acid, 2-6 parts of ammonium chloride, 0.5-1 parts of folic acid, 1-3 parts of chitosan oligosaccharide, gypsum powder 3-8
Part, 5-10 parts of Shitake Mushroom P.E, 5-10 parts of glutinous rehmannia extract, 5-10 parts of Herba Plantaginis extract, 10-20 parts of capejasmine extract, nothing
Water glucose is supplemented to 100 parts.
In the present invention, the Shitake Mushroom P.E, glutinous rehmannia extract, Herba Plantaginis extract, capejasmine extract can pass through city
Purchase obtains.
Vitamin C has the stably excreting for guaranteeing corticosteroid hormone and carnitine, maintains higher feed intake, increases
Human body immune function inhibits body temperature to rise, protect glutathione and enzyme guarantee cell integrality and metabolism it is normal into
Row, improves stress ability of body and other effects.
Taurine has extensive biological function, is not only an important factor for maintaining organismic internal environment stable state, Er Qie
It adjusts and is played an important role in the normal physiological functions of systems such as neural, cardiovascular, immune and endocrine.
Vitamin K, can resist drug generation stress, overcome the adverse reaction that stress be generated.
Chromium picolinate, chromium are microelement necessary to animal body, protein, lipid and the carbohydrate of wide participation body
Metabolism, heat stress can be alleviated by the secretion that changes cortin and the utilization for reinforcing glucose.As feed addictive,
It has effects that following：1, increase livestock meat, egg, milk, the output capacity of son and pup survival rate；2, promote livestock and poultry hypoglycemic, press down rouge
Fast-growth improves feed return rate；3, endocrine is adjusted, reproduction of domesti animals performance is enhanced；4, improve livestock body quality, improve
Lean meat percentage；5, reduce livestock and poultry stress, enhance livestock and poultry anti-stress ability；6, promote fowl poultry immune function, reduce livestock and poultry cultivation risk.
Fumaric acid, the approach for forming energy is shorter than glucose, can be used for phosphoric acid gland acid anhydride (ATP) under stress situation
Urgent synthesis, improves the resistance of body, increases the anti-stress ability of body.Fumaric acid can inhibit there are also sedation
Pivot nerve, reduces body activities, to reduce heat production.
γ-aminobutyric acid, a kind of natural amino acid and animal central nervous of important functional nonprotein composition
Most important blocking statutes neurotransmitter in system has calmness, resisting stress, promotion appetite, the strong kidney of strong liver, adjusting endocrine etc. more
Kind biological function.
Ammonium chloride, blood pH when ammonium can reduce heat stress of fowl mitigate respiratory alkalosis and cause damages.
Folic acid can enhance Development of Reproductive System function；Raw ovum of preventing miscarriage is prominent, and especially raising laying rate function is more excellent；It mentions
High immunity, growth promoting function are obvious；Antistress function is powerful.
Chitosan oligosaccharide is a kind of widow of degree of polymerization that chitosan is degraded through special biological enzyme technology between 2 ~ 20
Sugar product, molecular weight≤3200Da are water-soluble low molecular weight products preferable, function is big, bioactivity is high.Chitosan oligosaccharide
Have the multiple pharmacological effects such as anti-oxidant, antibacterial activity, anti-inflammatory promotion wound healing, immunological regulation, strengthen immunity, pig is mentioned
Seedling height performance, the absorption for reducing the death rate, promoting nutriment, the effect for improving immunity of organisms.
Gypsum powder, sweet in flavor, pungent, there is the effect of expelling pathogenic factors from muscles for clearing heat, relieving restlessness quench the thirst in property Great Cold, and gas headache body heat when removing, three is burnt
Big heat, skin heat, stomach middle diaphragm heat, expelling pathogenic factors from muscles by diaphoresis, only quenching one's thirst, it is inverse to be tired of, abdominal distension is panted breath, pharynx heat etc. cruelly.
Shitake Mushroom P.E, strengthen immunity is clearing heat and detoxicating, invigorating spleen to remove dampness.
Glutinous rehmannia extract, clearing heat and cooling blood, are promoted the production of body fluid at yin-nourishing, are disappeared for pyreticosis and polydipsia, yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, interior heat
Yearningly, leaf blood, spot dermexanthesis.
Herba Plantaginis extract, reducing fever and causing diuresis, eliminating the phlegm, cool blood, removing toxic substances, for edema and little urine, puckery pain of heat gonorrhea, summer-heat and damp dysentery,
Phlegm-heat cough, haematemesis, bleeding from five sense organs or subcutaneous tissue, carbuncle sore tumefacting virus.
Capejasmine extract, purging intense heat relieving restlessness, reducing fever and causing diuresis, removing pattogenic heat from the blood and toxic material from the body, for Vexed, red eye, swell pain etc..
The above Drug combination, not only can nutrition enhancing, release stress, but also adjustable Abwehrkraft des Koepers improves immune
Power etc., can prevent caused by a variety of causes stress and to reduce due to stress caused by a harm to the system, and be without residual
The drug having no drug resistance is stayed, safely and effectively.
Preparation method includes the following steps：
The first step prepares pre-mixing agent A：Vitamin K, chromium picolinate, folic acid are weighed in proportion, after mixing, then take anhydrous grape
It is sugared appropriate, it mixes by equal increments method to 4 ~ 6 parts, pre-mixing agent A is made；
Second step prepares pre-mixing agent B：Pre-mixing agent A and ammonium chloride, chitosan oligosaccharide, gypsum powder are taken, is uniformly mixed, pre-mixing agent is made
B；
Third step takes remaining DEXTROSE ANHYDROUS, sequentially adds pre-mixing agent B, vitamin C, taurine, fumaric acid, γ-ammonia
Base butyric acid, Shitake Mushroom P.E, glutinous rehmannia extract, Herba Plantaginis extract, capejasmine extract are uniformly mixed answering to get resisting stress
Square preparation.
The application method of compound preparation of the present invention：Mixed drink, every 100g are watered 100kg, can be used for a long time.
The present invention has the advantage that and beneficial effect：（1）Animal nutrition can be enhanced in the present invention, and can prevent various originals
Because caused by stress and reduce due to stress caused by a series of harm；（2）The method can significantly improve the bodies of livestock and poultry to exempt from
Epidemic disease power enhances disease resistance；（3）Raw material sources of the present invention are abundant, and production technology is easy；（4）Inventive mixture is ultra micro
Powder, into body after be easy to be absorbed, and clinical use is convenient, is suitble to group to use, uses manpower and material resources sparingly；（5）The present invention
Each component content is clear, quality controllable.
Specific embodiment
Explanation, but protection model of the invention are further explained to technical solution of the present invention combined with specific embodiments below
It encloses and is not limited thereto.
In following embodiment and reference examples, Shitake Mushroom P.E reaches Biotechnology Co., Ltd, rule purchased from Sichuan perseverance Easthome
Lattice：Lentinan >=40%；Glutinous rehmannia extract reaches Biotechnology Co., Ltd, specification 25: 1 purchased from Sichuan perseverance Easthome；Asiatic plantain
Extract reaches Biotechnology Co., Ltd, specification 25: 1 purchased from Sichuan perseverance Easthome；Capejasmine extract, purchased from Sichuan, perseverance Easthome reaches
Biotechnology Co., Ltd, specification 15: 1.
Embodiment 1-3 and reference examples 1-2
A kind of compound preparation of resisting stress, composition（In parts by weight）It is shown in Table 1-1 and table 1-2.
The preparation method of embodiment 1-3 product, includes the following steps：
The first step prepares pre-mixing agent A：Vitamin K, chromium picolinate, folic acid are weighed, after mixing, then takes DEXTROSE ANHYDROUS appropriate,
It mixes by equal increments method to 5 parts, pre-mixing agent A is made；
Second step prepares pre-mixing agent B：Ammonium chloride, chitosan oligosaccharide, gypsum powder are weighed, is added to the mixer, is pre-mixed 5 minutes, system
Obtain pre-mixing agent B；
Third step takes remaining DEXTROSE ANHYDROUS, sequentially adds pre-mixing agent B, vitamin C, taurine, fumaric acid, γ-ammonia
Base butyric acid, Shitake Mushroom P.E, glutinous rehmannia extract, Herba Plantaginis extract, capejasmine extract are uniformly mixed to get product.
The preparation method of 1 product of reference examples：Weigh vitamin C, vitamin K, chromium picolinate, fumaric acid, gamma-amino
Butyric acid, ammonium chloride, folic acid, chitosan oligosaccharide, DEXTROSE ANHYDROUS, are added to the mixer, and stir 30 minutes to get product.
The preparation method of 2 product of reference examples：Gypsum powder, Shitake Mushroom P.E, glutinous rehmannia extract, Asiatic plantain is weighed to extract
Object, capejasmine extract, DEXTROSE ANHYDROUS, are added to the mixer, and stir 30 minutes to get product.
The therapeutic effect of influence and grice diarrhoea of the compound preparation of the present invention to intestine of young pigs flora
It carries out as follows：
（One）Drug and reagent
Trial drug：Compound preparation product prepared by embodiment 1,2,3；
Control drug：Compound preparation product prepared by reference examples 1,2；
Blank group：Any drug is not added.
（Two）Test method
（1）Experimental design：Select parity, weight be close, sodium selenite 120 of the identical 20kg of kind or so it is dynamic as test
Object, is randomly divided into 6 groups, and every group 20, wherein 3 test groups, 2 control groups, 1 blank group.
Within the scope of 35-37 DEG C, 3 test groups and 2 control groups press the administration of 0.1% pitch-based sphere respectively.It takes and freely adopts
Food, epidemic prevention, management measure and daily consistent, with 15 days for a test period.Specific adding method is as follows：
Test group 1：Mixed drink, every 1 product of 100g embodiment are watered 100kg, freely drink, and continuous 15 days；
Test group 2：Mixed drink, every 2 product of 100g embodiment are watered 100kg, freely drink, and continuous 15 days；
Test group 3：Mixed drink, every 3 product of 100g embodiment are watered 100kg, freely drink, and continuous 15 days；
Control group 1：Mixed drink, every 1 product of 100g reference examples are watered 100kg, freely drink, and continuous 15 days；
Control group 2：Mixed drink, every 2 product of 100g reference examples are watered 100kg, freely drink, and continuous 15 days；
Blank group：It is not administered, free water.
The project of observing and recording has：Main includes average feed consumption, daily gain, feedstuff-meat ratio.
（2）As a result with analysis
As can be seen from Table 2：Test group average daily gain is 836g, and 142g, 195g is respectively increased than control group 1 and 2, compares blank
Group improves 335.Wherein 3 increase rate of test group is maximum, and daily gain reaches 879g, than control group 1 and 2 be respectively increased 185g,
238g improves 378g than blank group, and it is respectively 2.19,2.18,2.17 that per kilogram weight gain feed consumption, which tests 1,2,3 group, compares control group
It is high with the feed conversion rate of blank group.3 feed conversion rate highest of test group.Explanation：In heat stress, test group can be very
The stress disorders for eliminating animal well, do not influence normal growth rate.
Claims (2)
1. a kind of compound preparation of resisting stress, which is characterized in that by the sum of parts by weight be 100 parts in terms of, be grouped as by following groups：
5-10 parts of vitamin C, 0.1-0.3 parts of vitamin K, 0.02-0.05 parts of chromium picolinate, prolongs recklessly 5-10 parts of taurine
5-10 parts of carboxylic acid, 10-20 parts of γ-aminobutyric acid, 2-6 parts of ammonium chloride, 0.5-1 parts of folic acid, 1-3 parts of chitosan oligosaccharide, gypsum powder 3-8
Part, 5-10 parts of Shitake Mushroom P.E, 5-10 parts of glutinous rehmannia extract, 5-10 parts of Herba Plantaginis extract, 10-20 parts of capejasmine extract, nothing
Water glucose is supplemented to 100 parts.
2. a kind of method for the compound preparation for preparing resisting stress as claimed in claim 1 or 2, which is characterized in that including following
Step：
The first step prepares pre-mixing agent A：Vitamin K, chromium picolinate, folic acid are weighed in proportion, after mixing, then take anhydrous grape
It is sugared appropriate, it mixes by equal increments method to 4 ~ 6 parts, pre-mixing agent A is made；
Second step prepares pre-mixing agent B：Pre-mixing agent A and ammonium chloride, chitosan oligosaccharide, gypsum powder are taken, is uniformly mixed, pre-mixing agent is made
B；
Third step takes remaining DEXTROSE ANHYDROUS, sequentially adds pre-mixing agent B, vitamin C, taurine, fumaric acid, γ-ammonia
Base butyric acid, Shitake Mushroom P.E, glutinous rehmannia extract, Herba Plantaginis extract, capejasmine extract are uniformly mixed answering to get resisting stress
Square preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201810610714.2A CN108887474A (en) | 2018-06-14 | 2018-06-14 | A kind of compound preparation of resisting stress and preparation method thereof |
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| CN201810610714.2A CN108887474A (en) | 2018-06-14 | 2018-06-14 | A kind of compound preparation of resisting stress and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111513199A (en) * | 2019-12-23 | 2020-08-11 | 广州傲农生物科技有限公司 | Pig feed additive and preparation method and application thereof |
| CN112294802A (en) * | 2020-11-16 | 2021-02-02 | 佛山市顺德区活宝源生物科技有限公司 | Anti-stress preparation for reducing fry transportation loss and preparation process and use method thereof |
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| CN1608487A (en) * | 2003-10-23 | 2005-04-27 | 济南海得贝海洋生物工程有限公司 | Feed additive containing chitin oligose and its prepn and use |
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| CN111513199A (en) * | 2019-12-23 | 2020-08-11 | 广州傲农生物科技有限公司 | Pig feed additive and preparation method and application thereof |
| CN112294802A (en) * | 2020-11-16 | 2021-02-02 | 佛山市顺德区活宝源生物科技有限公司 | Anti-stress preparation for reducing fry transportation loss and preparation process and use method thereof |
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