CN105124162A - Heat stress resistant compound preparation and preparation method thereof - Google Patents

Heat stress resistant compound preparation and preparation method thereof Download PDF

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Publication number
CN105124162A
CN105124162A CN201510459628.2A CN201510459628A CN105124162A CN 105124162 A CN105124162 A CN 105124162A CN 201510459628 A CN201510459628 A CN 201510459628A CN 105124162 A CN105124162 A CN 105124162A
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China
Prior art keywords
compound preparation
heat stress
preparation
parts
vitamin
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CN201510459628.2A
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Chinese (zh)
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孙书华
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Zhengzhou Saike Pharmaceutical Technology Co Ltd
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Zhengzhou Saike Pharmaceutical Technology Co Ltd
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Priority to CN201510459628.2A priority Critical patent/CN105124162A/en
Publication of CN105124162A publication Critical patent/CN105124162A/en
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Abstract

The invention belongs to the compound preparation field of livestock and poultry, and mainly relates to a heat stress resistant compound preparation and a preparation method thereof. The compound preparation consists of the following raw materials: lysine, potassium chloride, sodium hydrogen carbonate, vitamin C, vitamin E, chromium picolinate, citric acid, licorice and dried orange peels. The compound preparation is relative good in improving animal feed intake and promoting appetite under relative high temperature conditions, thus indicating that the compound preparation can significantly improve the livestock and poultry immunity, enhance disease resistance, and resist against heat stress.

Description

A kind of compound preparation for anti-heat stress and preparation method thereof
Technical field
The invention belongs to livestock and poultry and use compound preparation field, relate generally to a kind of compound preparation for anti-heat stress and preparation method thereof.
Background technology
When heat stress refers to that animal is subject to the thermal stimulus exceeding itself Thermoregulation ability scope, body is caused to produce the summation of non-specific physiological reaction.
Can reduce the excitability of body feeding center under hot environment, cause neuroendocrine disorders, make the hormone secretion such as thyroxine, adrenaline disorderly, human body immune function declines.Therefore the harm that heat stress comes to industrial belt of raising pigs is immeasurable, is mainly manifested in following several respects: 1. feed intake reduces, grower pigs weightening finish slowly.2. pig breeding dysfunction is planted, sow hypo-ovaria, miscarriage, conception rate decline, the increase of stillborn foetus number, lactation amount decline, piglet survival ratio reduction etc.; The decline of herd boar hyposexuality, semen quality, sperm quantity minimizing, vigor reduction, abnormal rate rising etc.3. the disease such as dermatitis nephrotic syndrome, piglet white scour, unknown high fever, chronic ileitis increases.4. meat quality reduces, and produces PSE or DFD meat.5. feed goes mouldy, and mosquitos and flies is increased.
Heat stress not only affects behavior and the production performance of pig, and all causes serious impact to the immunologic function of pig, reproductive performance and meat quality etc.Along with the raising of global warming, pig industry intensive degree, the loss that heat stress comes to industrial belt of raising pigs, especially in the south China area of summer high temperature humidity, will be on the rise.Therefore, how to slow down heat stress and current pig industry problem demanding prompt solution has been become to the harm of Swine Production and the production performance improved under its hot conditions.
Summary of the invention
The object of the present invention is to provide and be a kind ofly applicable to compound preparation of livestock and poultry anti-heat stress and preparation method thereof.
For achieving the above object, the present invention is by the following technical solutions:
A kind of compound preparation for anti-heat stress, with parts by weight, it consists of: lysine 5 ~ 10 parts, 5 ~ 10 parts, potassium chloride, sodium acid carbonate 10 ~ 15 parts, vitamin C 5 ~ 10 parts, vitamin E2 .5 ~ 5 part, chromium picolinate 0.01 ~ 0.05 part, citric acid 5 ~ 10 parts, 20 ~ 30 parts, Radix Glycyrrhizae and dried orange peel 25 ~ 35 parts.
For the preparation method of the compound preparation of anti-heat stress, comprise the following steps: 1) first get chromium picolinate and lysine in proportion, be mixed to get mixture one by equal increments method; 2) mixture one and potassium chloride, sodium acid carbonate, vitamin C, vitamin E, citric acid mix in proportion to obtain mixture two; 3) proportionally stir with mixture two after Radix Glycyrrhizae, dried orange peel carry out ultramicro grinding respectively, to obtain final product.
The using method of compound preparation of the present invention: for pig, every 1000g compound preparation mix fodder 1000kg, namely Pitch-based sphere is 0.1%, and mixed feeding is used in conjunction 5 ~ 7 days.
In raw material used in the present invention, lysine can improve the production performance under heat stress condition, and quantity of heat production is lower than normal protein level; In addition, add lysine and the amino acid of daily ration is more balanced, whole amino acid whose utilization rate is improved, reduces and discharge with the nitrogen of form of urea, thus alleviate the impact of Heat-temperature stress; Under heat stress condition, when diet crude protein level is reduced to 14.2% by 17.6%, add lysine, the feed intake of lactating sow can be improved, reduce body weight loss, and on the growth performance of piglet without impact.There is the adding of potassium chloride the effect maintaining intracellular osmotic pressure and body acid-base balance.Sodium acid carbonate have dissolve mucus, in and hydrochloric acid in gastric juice, stomach invigorating and orectic effect, absorb in body and can supplement sodium ion, maintain acid-base balance, slow down respiratory alkalosis.VC have ensure corticosteroid hormone and carnitine stably excreting, maintain higher feed intake, increase human body immune function, suppress body temperature to rise, protection glutathione and enzyme, ensure the integrality of cell and metabolicly normally to carry out, the effect such as the emergency capability that improves body.VE has anti-oxidant, immune stimulatory organ, reduction cell membrane permeability, adjustment serum T 3, T4 concentration effect.Pyridine carboxylic acid is coughed up, and chromium is the required trace element of animal body, the metabolism of the protein of wide participation body, lipid and carbohydrate, alleviates heat stress by the secretion that changes cortin and the utilization of strengthening glucose; Pyridine carboxylic acid is coughed up as feed addictive, and it has following effect: 1, increase livestock meat, egg, milk, young output capacity and pup survival rate; 2, promote that livestock and poultry hypoglycemic presses down fat and grows fast, improve feed return rate; 3, regulate endocrine, strengthen reproduction of domesti animals performance; 4, improve livestock body quality, improve lean meat percentage; 5, reduce livestock and poultry stress, strengthen livestock and poultry anti-stress abilities; 6, promote fowl poultry immune function, reduce livestock and poultry cultivation risk.Citric acid, accelerated breathing during pig high temperature, a large amount of CO 2breathe out external, cause body pH value to raise, easily respiratory alkalosis occurs.In feed or drinking-water, add organic acid, adjustable acid-base balance, alleviate heat stress.Radix Glycyrrhizae, is the dry root welding technology of glycyrrhizic legume, glycyrrhiza inflate bat or glycyrrhiza glabra, invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription, cushion toxicity, strong.Dried orange peel is the maturate peel of rutaceae orange and variety thereof, regulating qi-flowing for strengthening spleen, and in tune, eliminating dampness, reduces phlegm, and cures mainly abdominal fullness and distention or pain, the indigestion of the taste stagnation of the circulation of vital energy, the abdominal distension uncomfortable in chest in wet turbid resistance, indigestion and loss of appetite loose stool, the wet cough and asthma stopping up lung of phlegm; For chest gastral cavity turgor, the few vomiting and diarrhoea of food, coughing with a lot of sputum.
Each ingredient combination of the present invention uses, and can regulate the stress ability of body from many aspects, reduce a series of harm because heat stress causes, and be the raw material that noresidue has no drug resistance, safe and effective! The advantage that the present invention has and beneficial effect: (1) the present invention can significantly improve the immunity of organisms of livestock and poultry, strengthen resistance against diseases, to anti-heat stress; (2) the present invention can improve the feed intake of animal well, promotes appetite; (3) inventive mixture abundant raw material source, and production technology is easy; (4) inventive mixture is easily absorbed after entering body, and clinical administration is convenient, is applicable to colony's administration, uses manpower and material resources sparingly; (5) medicament contg of the present invention is clear and definite, and administration is accurate, quality controllable.
Detailed description of the invention
Below by way of enforcement, the present invention is described further, but protection scope of the present invention is not limited thereto.
When preparing for the compound preparation of anti-heat stress described in embodiment 1-3, comprise the following steps: 1) first chromium picolinate and lysine are mixed to get mixture one by equal increments method; 2) mixture one mixes to obtain mixture two with potassium chloride, sodium acid carbonate, vitamin C, vitamin E, citric acid; 3) be placed in mixer with mixture two after Radix Glycyrrhizae, dried orange peel carry out ultramicro grinding respectively, stir and stir for 30 minutes, to obtain final product.
Effect experimental: the somatotrophic contrast test of compound preparation getting fat of the present invention
Carry out as follows:
(1) medicine and reagent
Trial drug group: the compound preparation prepared by embodiment 1,2,3;
Control drug group: (the prebiotic thing Co., Ltd in Shanxi million) is fallen apart in relieving summer-heat heat resistanceheat resistant
Blank group: do not add any medicine
(2) test method
(1) experimental design: select parity, body weight close, in the health of about the 50kg that kind is identical, pig 100 is as experimental animal, is divided into 5 groups at random, often organizes 20, wherein 3 test group, 1 control group, 1 blank group.
Within the scope of room temperature 37-39 degree, 3 test group are respectively by 0.1% Pitch-based sphere (every 1000g compound preparation spice 1000kg) administration, and control group is pressed 1000kg feed and added control drug 1000g, and the feed of blank group does not add medicine.Concrete grammar is: taking free choice feeding, epidemic prevention, control measures consistent with daily, was a test period with 15 days.
Basal diet is corn-soybean meal type daily ration.
Observed and recorded project mainly comprises: average feed consumption, daily gain, feedstuff-meat ratio.
(2) results and analysis
Daily gain, feedstuff-meat ratio compare
As can be seen from the above table, test group average daily gain is 945g, improves 140g than control group, improves 232g than blank group.Wherein test group 2 increase rate is maximum, and daily gain reaches 976g, improves 171g than control group, improves 263g than blank group, and per kilogram weightening finish feed consumption test 1,2,3 group is respectively 2.10,2.07,2.11, all higher than the feed conversion rate of control group and blank group.Test group 2 feed conversion rate is the highest.The feed intake of animal can be improved when above description of test compound preparation of the present invention room temperature is higher well, promote appetite, and then illustrate that this compound preparation can significantly improve the immunity of organisms of livestock and poultry, strengthen resistance against diseases, to anti-heat stress.

Claims (2)

1. the compound preparation for anti-heat stress, it is characterized in that, with parts by weight, it consists of: lysine 5 ~ 10 parts, 5 ~ 10 parts, potassium chloride, sodium acid carbonate 10 ~ 15 parts, vitamin C 5 ~ 10 parts, vitamin E2 .5 ~ 5 part, chromium picolinate 0.01 ~ 0.05 part, citric acid 5 ~ 10 parts, 20 ~ 30 parts, Radix Glycyrrhizae and dried orange peel 25 ~ 35 parts.
2. described in claim 1 for the preparation method of the compound preparation of anti-heat stress, it is characterized in that, comprise the following steps: 1) first get chromium picolinate and lysine in proportion, be mixed to get mixture one by equal increments method; 2) mixture one and potassium chloride, sodium acid carbonate, vitamin C, vitamin E, citric acid mix in proportion to obtain mixture two; 3) proportionally stir with mixture two after Radix Glycyrrhizae, dried orange peel carry out ultramicro grinding respectively, to obtain final product.
CN201510459628.2A 2015-07-31 2015-07-31 Heat stress resistant compound preparation and preparation method thereof Pending CN105124162A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107647115A (en) * 2017-10-12 2018-02-02 亚太星原农牧科技海安有限公司 A kind of feed addictive of anti-heat stress and preparation method and application
CN107751558A (en) * 2016-08-22 2018-03-06 沈阳伟嘉牧业技术有限公司 A kind of Chinese medicine preparation and preparation method of anti-milking sow heat stress increase lactation amount
CN108740585A (en) * 2018-06-11 2018-11-06 金寨毛竹湾农业科技有限公司 A kind of pannage of summer feeding
CN108887474A (en) * 2018-06-14 2018-11-27 河南省帝方生物制药有限公司 A kind of compound preparation of resisting stress and preparation method thereof
CN115212248A (en) * 2022-07-27 2022-10-21 佛山市南海东方澳龙制药有限公司 Composition for animals with heat stress resistance and preparation method thereof

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CN102813060A (en) * 2012-08-30 2012-12-12 北京市爱德利都饲料科技开发有限公司 Swine compound premix for improving heat stress resistance
CN103549199A (en) * 2013-11-06 2014-02-05 安徽农业大学 Formula feed additive for enhancing thermal stress resistance of pigs
CN104758556A (en) * 2014-12-10 2015-07-08 北京康华远景科技股份有限公司 Compound preparation for resisting heat stress of animals and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101053370A (en) * 2007-05-25 2007-10-17 刘定发 Anti stress immunity enhancing agent for pig
CN102813060A (en) * 2012-08-30 2012-12-12 北京市爱德利都饲料科技开发有限公司 Swine compound premix for improving heat stress resistance
CN103549199A (en) * 2013-11-06 2014-02-05 安徽农业大学 Formula feed additive for enhancing thermal stress resistance of pigs
CN104758556A (en) * 2014-12-10 2015-07-08 北京康华远景科技股份有限公司 Compound preparation for resisting heat stress of animals and preparation method thereof

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107751558A (en) * 2016-08-22 2018-03-06 沈阳伟嘉牧业技术有限公司 A kind of Chinese medicine preparation and preparation method of anti-milking sow heat stress increase lactation amount
CN107647115A (en) * 2017-10-12 2018-02-02 亚太星原农牧科技海安有限公司 A kind of feed addictive of anti-heat stress and preparation method and application
CN108740585A (en) * 2018-06-11 2018-11-06 金寨毛竹湾农业科技有限公司 A kind of pannage of summer feeding
CN108887474A (en) * 2018-06-14 2018-11-27 河南省帝方生物制药有限公司 A kind of compound preparation of resisting stress and preparation method thereof
CN115212248A (en) * 2022-07-27 2022-10-21 佛山市南海东方澳龙制药有限公司 Composition for animals with heat stress resistance and preparation method thereof

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Application publication date: 20151209