CN108852937A - A kind of Moringa freckle removing and whitening face cream and preparation method thereof - Google Patents
A kind of Moringa freckle removing and whitening face cream and preparation method thereof Download PDFInfo
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- CN108852937A CN108852937A CN201810921905.0A CN201810921905A CN108852937A CN 108852937 A CN108852937 A CN 108852937A CN 201810921905 A CN201810921905 A CN 201810921905A CN 108852937 A CN108852937 A CN 108852937A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Abstract
The present invention provides a kind of Moringa freckle removing and whitening face creams, contain the following parts by weight：1-10 parts of Moringa extractive of general flavone, 0.05-1 parts of litsea citrate oil, 0.1-2 parts of olive oil, 1-5 parts of Rosa Damascana.Moringa freckle removing and whitening face cream of the invention is prepared by following methods：Carbomer, glycerol, water are placed in container after shaking is sufficiently mixed, heating makes its swelling, Tween 80 is added after standing overnight, it stirs evenly dispersed to Tween 80, then 70% sorbitol solution, water, Moringa extractive of general flavone, poloxamer, ethylparaben, litsea citrate oil, olive oil, Rosa Damascana and triethanolamine are sequentially added, pH value is finally adjusted to 6.0, stirring to formation gel is to get Moringa general flavone face cream.Moringa freckle removing and whitening face cream of the present invention cosmetic material of the invention is cheap, and materials are convenient, non-stimulated to skin, and various active substance acts synergistically on skin, and freckle effect is better than ordinary cosmetics.
Description
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of Moringa freckle removing and whitening face cream and preparation method thereof.
Background technique
The colour of skin of people be according to generate the activity of melanocyte of melanin, the distribution of blood vessel, skin thickness, with
And the pigment of carotenoid, bilirubin et al. inside and outside contains the various factors such as there is something special and determines.In particular, melanocyte
It is most important factor by the pigment for being called melanin that the effect of the various enzymes such as tyrosinase generates.The pigment of melanin
In formation, the environmental factors such as the relevant physiologic factor such as inherent cause, hormone secretion, pressure and ultraviolet light irradiation can be generated
It influences.Melanin is present in skin, prevents ultraviolet damage etc., thus play an important role to protection body, but melanin
When excessive generation, pigmentation and skin aging will be accelerated, and induce the principal element of cutaneum carcinoma.In order to treat or subtract
Light skin pigmentation disorder calmness symptom and to be exposed to melanin caused by ultraviolet light etc. excessively calm, in the past by ascorbic acid,
Kojic acid, arbutin, hydroquinone, glutathione and these derivative have and hinder active substance of Tyrosinase etc.
Be blended in cosmetics or pharmaceuticals and use, but due to there are insufficient whitening effect, to the safety of skin and mixed
It closes in cosmetics the problems such as dosage form stability, usability is restricted.
Moringa (Moringa) is also known as drumstick tree (Drumstick tree), is perennial tropical deciduous tree, originates in print
Degree is northern.Moringa not only the functional components such as vitamin rich in, unsaturated fatty acid, polyphenol, flavone compound and
Several mineral materials also have anti-oxidant, antibacterial, anti-inflammatory efficacy, can promote skin repair, inhibit melanin accumulation, play whitening
The effect of tender skin and reparation skin.
A kind of plant of the Moringa as rich in nutrition content, is more and more paid attention in recent years, but at this stage everybody
To on the market Moringa product percentage of intelligibility and acceptance it is still lower, and on the market also not yet on a large scale development and utilization Moringa grind
Medicine cosmetic made of system.
Summary of the invention
A kind of Moringa freckle removing and whitening face is provided it is an object of the invention to overcome above-mentioned the deficiencies in the prior art place
Frost, the raw extract of the face cream are pure plant essence, have anti-oxidant, whitening, moisturizing and other effects, can promote skin
It repairs, inhibits melanin accumulation, whitening and softening skin and skin regeneration function.
To achieve the above object, the technical solution adopted by the present invention is：
A kind of Moringa freckle removing and whitening face cream, contains the following parts by weight：1-10 parts of Moringa extractive of general flavone, mountain
Grey seed oil 0.05-1 parts, 0.1-2 parts of olive oil, 1-5 parts of Rosa Damascana.
Preferably, the Moringa freckle removing and whitening face cream, contains the following parts by weight：Moringa extractive of general flavone
1.5-6 parts, 0.1-0.8 parts of litsea citrate oil, 0.2-1.5 parts of olive oil, 2-4 parts of Rosa Damascana.
Preferably, the Moringa freckle removing and whitening face cream, contains the following parts by weight：Moringa extractive of general flavone 2
Part, 0.1 part of litsea citrate oil, 0.3 part of olive oil, 3 parts of Rosa Damascana.
Further, the Moringa freckle removing and whitening face cream, also contains the following parts by weight：0.5-2 parts of carbomer,
3-7 parts of glycerol, 0.5-1 parts of Tween 80,1-3 parts of 70% sorbitol solution, 1-3 parts of poloxamer, ethylparaben 0.1-0.5
Part, 1-5 parts of triethanolamine.
Preferably, the Moringa freckle removing and whitening face cream, also contains the following parts by weight：1.2 parts of carbomer, glycerol
6.3 parts, 0.7 part of Tween 80,2.7 parts of 70% sorbitol solution, 1 part of poloxamer, 0.3 part of ethylparaben, triethanolamine 2
Part.
Further, the Moringa extractive of general flavone is prepared using following methods：It is added after leaf of Moringa is crushed
70% ethyl alcohol, after Ultrasonic Heating, filtrate decompression is concentrated in vacuo to get Moringa extractive of general flavone by filtering.
The present invention also provides a kind of preparation methods of Moringa freckle removing and whitening face cream, include the following steps：
Carbomer, glycerol, water are placed in container after shaking is sufficiently mixed, being heated to 50 DEG C makes its swelling, stands overnight
After Tween 80 is added, stirred along same direction it is evenly dispersed to Tween 80, then sequentially add 70% sorbitol solution, water,
Moringa extractive of general flavone, poloxamer, ethylparaben, litsea citrate oil, olive oil, Rosa Damascana and triethanolamine, finally
PH value is adjusted to 6.0, stirring to formation gel is to get Moringa freckle removing and whitening face cream.
Component and its effect in Moringa freckle removing and whitening face cream of the invention are described as follows：
Moringa general flavone can be such that body Scavenging ability and oxidation resistance is improved, on phenolic hydroxyl group
Then hydrogen atom can generate flavones free radical, then carry out the anti-of next step with other free radicals in conjunction with peroxy radical
It answers, free chain reaction is terminated with this, is finally reached antioxidation, while Moringa general flavone can effectively inhibit junket ammonia
The activity of sour enzyme, to reduce the ability that melanocyte generates melanin, and then the effect of reach whitening.
The linoleic acid contained in olive oil is less, and iodine number is lower, and the unsaturated bond contained is few, with other liquid fats
It compares, it is not oxidizable in air, it is not susceptible to corruption.And the squalene splendid with skin affinity is rich in olive oil
And essential fatty acid, absorb rapidly and Moringa flavones and Rosa Damascana synergistic effect, can effectively keep skin elasticity and
Moist, contained monounsaturated fatty acids abundant and vitamin E, K, A, D etc. and phenols antioxidant, can disappear in olive oil
Except facial wrinkles, skin aging is prevented, there is the effect of preferable skin care.
Rosa Damascana can not only adjust female incretion, nourish uterus, the effect of beauty and skin care is fine, and can lead to
Supported within crossing it is external have the function that Kohakuhi, promote melanin to decompose with this, dry skin made to obtain certain change
It is kind, it allows skin to restore elasticity, is the volatile oil for being suitable for health care.Rosa Damascana is Pure natural plant essential oil, has and decomposes pigment
Function, the Fast-Balance of moisture and nutrient can be made, make cytotoxic quick discharge, with this to skin internal and external environment
Entirety is adjusted and controls, and the effect of Kohakuhi promotes melanin to decompose with this；With anti-aging, prevent the hair of wrinkle
Raw and enhancing moisture-keeping efficacy, is suitble to various skin quality types.
Litsea citrate oil has good permeability and good amalgamation, by directly exciting the items of Skin Cell new old
Metabolic response inhibits oxygen radical activity, enhances blood flow, can continue replenishing water and preserving moisture, and also can control Tyrosinase oxidation shield
Skin maintenance, has anti-oxidant, wrinkle resistant, antiallergy and moisture-keeping efficacy.
The beneficial effects of the present invention are：Moringa freckle removing and whitening face cream of the invention has anti-containing Moringa general flavone
Oxidation, antibacterial, anti-inflammatory and other effects can promote skin repair, inhibit melanin accumulation, play good whitening antioxidation effect；
Rosa Damascana, olive oil and litsea citrate oil are also added into face cream of the invention, these types of ingredient plays synergistic effect, not only
Strengthen the whitening antioxidation function of product, moreover it is possible to effectively keep skin elasticity and moisten, promote the absorption of skin, simultaneously also
Slight rose scent is added, makes product more
Specific embodiment
For more concise displaying technical solution of the present invention, objects and advantages, combined with specific embodiments below
The present invention is described in further detail.
Embodiment 1
The Moringa freckle removing and whitening face cream of the present embodiment, contains the following parts by weight：1 part of Moringa extractive of general flavone,
0.05 part of litsea citrate oil, 0.1 part of olive oil, 1 part of Rosa Damascana, 0.5 part of carbomer, 3 parts of glycerol, 0.5 part of Tween 80,70%
1 part of sorbitol solution, 1 part of poloxamer, 0.1 part of ethylparaben, 1 part of triethanolamine.
The Moringa extractive of general flavone of the present embodiment is prepared by following methods：
Fresh leaf of Moringa is cleaned to be placed in 60 DEG C of baking ovens and is dried, coarse powder is ground into, 10 g of Moringa leaf coarse powder is taken to be added
The ethyl alcohol of 300ml 70%, after 52 DEG C of Ultrasonic Heatings extract 40min, filtering, by filtrate decompression be concentrated in vacuo to 50ml to get
Moringa extractive of general flavone.
The Moringa freckle removing and whitening face cream of the present embodiment is prepared using following methods：
Weigh 0.5 part of carbomer, 3 parts of glycerol be placed in a beaker, add 80 parts of distilled water, shaking is sufficiently mixed, in 50 DEG C of water
Swelling is heated in bath, after complete swelling, is stood overnight.Next day is added 0.5 part of Tween 80, and carries out along same direction
Stirring sequentially adds 70% sorbitol solution, 1 part and 42 parts distilled water after Tween 80 is evenly dispersed in water, is added peppery
1 part of the wooden extractive of general flavone, 1 part of poloxamer, 0.1 part of ethylparaben, 0.05 part of litsea citrate oil, 0.1 part of olive oil and drop
Enter 3 parts of Rosa Damascana, is added 1 part of triethanolamine.PH value is adjusted to 6.0, same direction long agitation, until being formed sparkling and crystal-clear
Transparent, fine and smooth uniform gel is to get Moringa general flavone face cream.
Embodiment 2
The Moringa freckle removing and whitening face cream of the present embodiment, contains the following parts by weight：Moringa extractive of general flavone 10
Part, 1 part of litsea citrate oil, 2 parts of olive oil, 5 parts of Rosa Damascana, 2 parts of carbomer, 7 parts of glycerol, 1 part of Tween 80,70% sorbierite
3 parts of solution, 3 parts of poloxamer, 0.5 part of ethylparaben, three ethyl alcohol
The Moringa freckle removing and whitening face cream of the present embodiment and the preparation method of Moringa extractive of general flavone are all made of embodiment
1 preparation method.
Embodiment 3
The Moringa freckle removing and whitening face cream of the present embodiment, contains the following parts by weight：Moringa extractive of general flavone 1.5
Part, 0.1 part of litsea citrate oil, 0.2 part of olive oil, 2 parts of Rosa Damascana, 1 part of carbomer, 4 parts of glycerol, 0.9 part of Tween 80,70%
2 parts of sorbitol solution, 2 parts of poloxamer, 0.2 part of ethylparaben, 3 parts of triethanolamine.
The Moringa freckle removing and whitening face cream of the present embodiment and the preparation method of Moringa extractive of general flavone are all made of embodiment
1 preparation method.
Embodiment 4
The Moringa freckle removing and whitening face cream of the present embodiment, contains the following parts by weight：6 parts of Moringa extractive of general flavone,
0.8 part of litsea citrate oil, 1.5 parts of olive oil, 4 parts of Rosa Damascana, 2 parts of carbomer, 7 parts of glycerol, 1 part of Tween 80,70% sorb
3 parts of alcoholic solution, 3 parts of poloxamer, 0.5 part of ethylparaben, 4 parts of triethanolamine.
The Moringa freckle removing and whitening face cream of the present embodiment and the preparation method of Moringa extractive of general flavone are all made of embodiment
1 preparation method.
Embodiment 5
The Moringa freckle removing and whitening face cream of the present embodiment, contains the following parts by weight：2 parts of Moringa extractive of general flavone,
0.1 part of litsea citrate oil, 0.3 part of olive oil, 3 parts of Rosa Damascana, 1.2 parts of carbomer, 6.3 parts of glycerol, 0.7 part of Tween 80,
70% 2.7 parts of sorbitol solution, 1 part of poloxamer, 0.3 part of ethylparaben, 2 parts of triethanolamine.
The Moringa freckle removing and whitening face cream of the present embodiment and the preparation method of Moringa extractive of general flavone are all made of embodiment
1 preparation method.
Comparative example 1
The formula of the whitening cream of comparative example 1 is：0.1 part of litsea citrate oil, 0.3 part of olive oil, 3 parts of Rosa Damascana, card wave
1.2 parts of nurse, 6.3 parts of glycerol, 0.7 part of Tween 80,2.7 parts of 70% sorbitol solution, 1 part of poloxamer, ethylparaben 0.3
Part, 2 parts of triethanolamine.
Comparative example 2
The formula of the whitening cream of comparative example 2 is：2 parts of Moringa extractive of general flavone, 0.3 part of olive oil, Rosa Damascana 3
Part, 1.2 parts of carbomer, 6.3 parts of glycerol, 0.7 part of Tween 80,2.7 parts of 70% sorbitol solution, 1 part of poloxamer, nipalgin
0.3 part of ethyl ester, 2 parts of triethanolamine.
Comparative example 3
The formula of the whitening cream of comparative example 3 is：2 parts of Moringa extractive of general flavone, 0.1 part of litsea citrate oil, Rosa Damascana
3 parts, 1.2 parts of carbomer, 6.3 parts of glycerol, 0.7 part of Tween 80,2.7 parts of 70% sorbitol solution, 1 part of poloxamer, Ni Bo
0.3 part of golden ethyl ester, 2 parts of triethanolamine.
Comparative example 4
The formula of the whitening cream of comparative example 4 is：2 parts of Moringa extractive of general flavone, 0.1 part of litsea citrate oil, olive oil
0.3 part, 1.2 parts of carbomer, 6.3 parts of glycerol, 0.7 part of Tween 80,2.7 parts of 70% sorbitol solution, 1 part of poloxamer, Buddhist nun
Moor golden 0.3 part of ethyl ester, 2 parts of triethanolamine.
Table 1：The formula table of the face cream of embodiment 1-5 and comparative example 1-4：
Embodiment 1-5 is compared with the whitening antioxidation effect of comparative example 1-4：
Test one：The removing free radical effect assessment of Moringa freckle removing and whitening face cream of the present invention is tested
The face cream for taking 1-5 of the embodiment of the present invention and comparative example 1-4 is configured to the sample solution of 4mg/mL with PBS, point
Not with 1mL methanol solution, 1mL DPPH free radical methanol solution (2 × 10-4Mol/L), it is sufficiently mixed uniformly, stands 30min
Afterwards, with absorbance at spectrophotometric measurement 517nm, and its free radical scavenging activity is calculated with formula.Free radical scavenging activity (%)=
[(Ac-As/Ac)] × 100%, As：Absorbance of the sample containing determinand at 517nm；Ac：Sample without determinand
Absorbance at 517nm, the results are shown in Table 2 for the free radical scavenging activity (%) of 1-5 face cream of the embodiment of the present invention.
Table 2：The free radical scavenging activity (%) of 1-5 of the embodiment of the present invention and comparative example 1-2 face cream
| Tested material | Free radical scavenging activity |
| Embodiment 1 | 91.5% |
| Embodiment 2 | 95.5% |
| Embodiment 3 | 96.5% |
| Embodiment 4 | 94.7% |
| Embodiment 5 | 98.1% |
| Comparative example 1 | 69.5% |
| Comparative example 2 | 78.2% |
| Comparative example 3 | 58.2% |
| Comparative example 4 | 50.1% |
As shown in Table 2, it is added in Moringa extractive of general flavone, litsea citrate oil, olive oil or Rosa Damascana in face cream
One or more can reach anti-aging effects, but the effect for removing free radical does not add the extraction of Moringa general flavone simultaneously
Object, litsea citrate oil, the effect of olive oil and Rosa Damascana are strong, by Moringa extractive of general flavone, litsea citrate oil, olive oil and rose
Rare essential oil, which compound being added to, enhances the function that face cream removes free radical in face cream, play anti-ageing synergy, significantly high
In independent addition, the wherein free radical scavenging activity highest of embodiment 5, anti-aging ability is most strong, is of the invention best therefore
Embodiment.
Test two：The effect assessment test of the inhibition tyrosinase of Moringa freckle removing and whitening face cream of the present invention
The face cream for taking 1-5 of the embodiment of the present invention and comparative example 1-4 is configured to the sample solution of 4mg/mL with PBS, will
Tyrosinase is configured to the solution that concentration is 6.67ug/ml, and the solution of 0.5 mmol/L is configured to using L-3,4 dihydroxyphenylalanine as substrate.By sample
Product solution, tyrosinase solution and substrate solution in 37 DEG C of water-baths keep the temperature 30min after mixing, react after 1min with microplate reader into
Row measurement, Detection wavelength 475nm are recorded absorbance (A), and are calculated inhibiting rate (%).Inhibit tyrosinase calculation formula
For：Inhibiting rate (%)=[1- (A3-A4)/(A1-A2)] × 100%.
Table 3：The inhibitory activity against tyrosinase (%) of 1-5 of the embodiment of the present invention and comparative example 1-4 face cream
As shown in Table 3, it is added in Moringa extractive of general flavone, litsea citrate oil, olive oil or Rosa Damascana in face cream
Though one or two can inhibit tyrosinase activity, its effect is while not add Moringa extractive of general flavone, mountain grey
The effect of seed oil, olive oil and Rosa Damascana is strong, by Moringa extractive of general flavone, litsea citrate oil, olive oil and Rosa Damascana into
Row compounding, which is added to, enhances the function that face cream inhibits clear tyrosinase activity in face cream, play whitening de-black synergy, show
It writes and is higher than individually addition, wherein the inhibitory activity against tyrosinase highest of embodiment 5, anti-aging ability is most strong, is this therefore
The most preferred embodiment of invention.
Test three：The effect assessment of the whitening of Moringa freckle removing and whitening face cream of the present invention is tested
Test selection 50 people of female volunteers, measures melanin content in human skin, to the whitening function of cosmetic product
Effect is evaluated.1 day before cosmetics and continuous use cosmetics 14 days are being used using MEXAMETER MX18 skin pigment instrument
The melanin content of its skin of face is measured afterwards.Determination of the environment：It tests environment temperature (22 ± 1) DEG C, humidity (50 ± 5) % takes
Average value.Study subject uses a cosmetic product daily, and application method is：After cleaning facial skin, dry, it will with hand
Cosmetic applying is on facial skin.Study subject does not use other whitening products dduring test.It is higher to measure numerical value, says
Melanin content is higher in bright skin.
Calculation formula：Melanin reduced rate=(use 1 day before cosmetics melanin content-continuous use cosmetics 14
Melanin content after it) ÷ uses 1 day before cosmetics melanin content × 100%.Melanin reduced rate is higher, illustrates beauty
White effect is more obvious.
Table 4：Use the melanin reduced rate (%) of 1-5 of the embodiment of the present invention and comparative example 1-4 face cream
By table 4 as it can be seen that 1-5 of the embodiment of the present invention has white-skinned face function, the Moringa general flavone added in the comparative example is extracted
One or more of object, litsea citrate oil, olive oil or Rosa Damascana have whitening effect, but white-skinned face function is not as good as this hair
Bright whitening cream, therefore Moringa extractive of general flavone, litsea citrate oil, olive oil or Rosa Damascana are subjected to compounding addition and existed
In cosmetics, have whitening effect synergistic, be significantly higher than independent addition, wherein the melanin reduced rate of embodiment 5 is most
Height, whitening capability is most strong, is highly preferred embodiment of the present invention therefore.
Experiment four：The effect assessment of the nti-freckle of Moringa freckle removing and whitening face cream of the present invention is tested
Test method：Age bracket is chosen in 25 years old to 45 years old 80 volunteers, wherein male 20, women 60.
Cardinal symptom：Freckle, chloasma, sun spot, the colour of skin are obscure.Volunteer is randomly divided into 8 groups of test group and (is used
The embodiment of the present invention 1-5 Moringa freckle removing and whitening face cream), three groups of control group (use the product of comparative example 1-4 and commercially available same
Type products), every group of 10 people.
Test group：After daily face cleaning, the embodiment 1-5 cosmetics prepared are spread on into face before sleeping, do not apply other skin cares
Product, experimental period one month.
Control group:After daily face cleaning, the comparative example 1-4 cosmetics prepared or commercially available similar-type products are spread on into face before sleeping
Portion does not apply other skin care item, and one month experimental period, (wherein the component and content of commercially available similar-type products were：Saualane
22%, microcrystalline wax 6%, isopropyl myristate 6%, guar gum 0.5%, Licochalcone A 0.05, acteoside
0.15%, surplus is water).
Evaluation criterion:Experienced by patient's readme and computer compares dermatoglyph illustrated handbook and determines colour of skin whitening degree and color spot
Desalination degree.Effectively:The colour of skin highlights, color spot color dodge.In vain:It is not any change before the colour of skin and color spot and test.
Table 5：It is efficient (%) using the nti-freckle of 1-5 of the embodiment of the present invention and comparative example 1-4 and commercially available similar face cream
As shown in Table 5, the efficient of freckle removing and whitening face cream of the invention has good freckle effect up to 90% or more,
Effect is much higher than comparative example and same type nti-freckle product simultaneously.
Test five：The safety testing of Moringa freckle removing and whitening face cream of the present invention
Regular grade large ear rabbit 4 are selected, 2.4-2.8 kilograms of weight, body looks into animal no abnormality seen.
Environmental condition：Room temperature：22 DEG C -23 DEG C, relative humidity：66%-68%；
Test method：Foundation《Cosmetics health specification》The test of (version in 2007) acute skin irritation, it is small to test preceding 24
When, experimental animal back backbone diamond wool is cut, 3 centimetres of 3 cm x of unhairing range.Tested no originality 0.5g is taken directly to apply
It is put on the skin of right side, with the covering of clean gauze, with nonirritant immobilization with adhesive tape 2 hours.Other side is negative control.It removes
1 hour after going tested material, 24 hours, observation animal subject contact site dermoreaction in 72 hours 48 hours and keep a record.
Under this experimental condition, 1-5 freckle removing and whitening face cream of the embodiment of the present invention presses White Rabbit acute skin irritation test
Skin irritatin strength grading is nonirritant.
The Security test of 1-5 freckle removing and whitening face cream of the embodiment of the present invention：
It is safe and non-toxic that 1-5 freckle removing and whitening face cream of the embodiment of the present invention is demonstrated by animal experiment and human body patch test,
Human body patch test is carried out by our company professional.
Test six：Moringa freckle removing and whitening face cream quality evaluation
Face cream prepared by the embodiment of the present invention 1-5 with glossiness, sophistication, stretchability, centrifugal stability, resists cold
Stability and heat-resistant stability carry out comprehensive full evaluation, and 20 people is looked for score respectively.It the results are shown in Table 6.
Table 6：The evaluation result of Moringa freckle removing and whitening face cream indices
From the point of view of the average and evaluation of table 6, finished product gel glossiness is fine, and sophistication is good, no granular sensation, applies
Malleability is good, and centrifugal stability is good, resist cold, heat resistance it is preferable, face cream finished product indices are good.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention
Protect range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (7)
1. a kind of Moringa freckle removing and whitening face cream, which is characterized in that contain the following parts by weight：Moringa extractive of general flavone 1-
10 parts, 0.05-1 parts of litsea citrate oil, 0.1-2 parts of olive oil, 1-5 parts of Rosa Damascana.
2. Moringa freckle removing and whitening face cream as described in claim 1, which is characterized in that the Moringa freckle removing and whitening face cream includes
The component of following parts by weight：1.5-6 parts of Moringa extractive of general flavone, 0.1-0.8 parts of litsea citrate oil, 0.2-1.5 parts of olive oil, rose
Rare essential oil 2-4 parts.
3. Moringa freckle removing and whitening face cream as claimed in claim 2, which is characterized in that the Moringa freckle removing and whitening face cream includes
The component of following parts by weight：2 parts of Moringa extractive of general flavone, 0.1 part of litsea citrate oil, 0.3 part of olive oil, 3 parts of Rosa Damascana.
4. Moringa freckle removing and whitening face cream as described in claim 1, which is characterized in that the Moringa freckle removing and whitening face cream also wraps
Component containing following parts by weight：0.5-2 parts of carbomer, 3-7 parts of glycerol, 0.5-1 parts of Tween 80,70% sorbitol solution 1-3
Part, 1-3 parts of poloxamer, 0.1-0.5 parts of ethylparaben, 1-5 parts of triethanolamine.
5. Moringa freckle removing and whitening face cream as claimed in claim 4, which is characterized in that the Moringa freckle removing and whitening face cream also wraps
Component containing following parts by weight：1.2 parts of carbomer, 6.3 parts of glycerol, 0.7 part of Tween 80,2.7 parts of 70% sorbitol solution, pool
1 part of Luo Shamu, 0.3 part of ethylparaben, 2 parts of triethanolamine.
6. Moringa freckle removing and whitening face cream as described in any one of claims 1-3, which is characterized in that the Moringa general flavone extracts
Object is prepared using following methods：70% ethyl alcohol is added after leaf of Moringa is crushed, after Ultrasonic Heating, filtering subtracts filtrate
Pressure vacuum concentration is to get Moringa extractive of general flavone.
7. a kind of preparation method of Moringa freckle removing and whitening face cream as described in any one in claim 1-5, which is characterized in that including
Following steps：
Carbomer, glycerol, water are placed in container after shaking is sufficiently mixed, heating makes its swelling, and tween is added after standing overnight
80, stirring is evenly dispersed to Tween 80, then sequentially adds 70% sorbitol solution, water, Moringa extractive of general flavone, Bo Luosha
PH value is finally adjusted to 6.0, stirring to formation by nurse, ethylparaben, litsea citrate oil, olive oil, Rosa Damascana and triethanolamine
Gel is to get Moringa freckle removing and whitening face cream.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110464662A (en) * | 2019-09-04 | 2019-11-19 | 朱梅年 | A kind of freckle-removing beauty cream and preparation method thereof |
| CN111012687A (en) * | 2019-12-31 | 2020-04-17 | 中山大学新华学院 | Compound fisetin microemulsion gel and preparation method and application thereof |
| CN112972332A (en) * | 2021-03-03 | 2021-06-18 | 李培丰 | Rose whitening essence and preparation method thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012149436A2 (en) * | 2011-04-29 | 2012-11-01 | Garden Art Innovations, Llc | Cosmetic composition |
| KR20160091166A (en) * | 2015-01-23 | 2016-08-02 | 헤내스 주식회사 | natural cosmetic composition for removing callus and improving skin barrier function |
| CN105828810A (en) * | 2013-12-17 | 2016-08-03 | 玫琳凯有限公司 | Delivery of active ingredients from plant materials to skin |
| CN105963171A (en) * | 2016-04-29 | 2016-09-28 | 安徽恋尚你食品有限公司 | Moringa skin lotion and preparation method thereof |
| CN106137820A (en) * | 2015-04-20 | 2016-11-23 | 李蓉 | A kind of moisturizing whitening cream |
| US20170056464A1 (en) * | 2015-08-28 | 2017-03-02 | Winston C. V. Parris | Composition for musculoskeletal pain |
| CN107427456A (en) * | 2015-03-16 | 2017-12-01 | 博姿有限公司 | The topical cosmetic agents of Green Tea Extract |
-
2018
- 2018-08-14 CN CN201810921905.0A patent/CN108852937B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012149436A2 (en) * | 2011-04-29 | 2012-11-01 | Garden Art Innovations, Llc | Cosmetic composition |
| CN105828810A (en) * | 2013-12-17 | 2016-08-03 | 玫琳凯有限公司 | Delivery of active ingredients from plant materials to skin |
| KR20160091166A (en) * | 2015-01-23 | 2016-08-02 | 헤내스 주식회사 | natural cosmetic composition for removing callus and improving skin barrier function |
| CN107427456A (en) * | 2015-03-16 | 2017-12-01 | 博姿有限公司 | The topical cosmetic agents of Green Tea Extract |
| CN106137820A (en) * | 2015-04-20 | 2016-11-23 | 李蓉 | A kind of moisturizing whitening cream |
| US20170056464A1 (en) * | 2015-08-28 | 2017-03-02 | Winston C. V. Parris | Composition for musculoskeletal pain |
| CN105963171A (en) * | 2016-04-29 | 2016-09-28 | 安徽恋尚你食品有限公司 | Moringa skin lotion and preparation method thereof |
Non-Patent Citations (8)
| Title |
|---|
| XIAO-WEI HUANG等: ""Potential cosmetic application of essential oil extracted from Litsea cubeba fruits from China"", 《THE JOURNAL OF ESSENTIAL OIL RESEARCH》 * |
| YING WANG等: ""Antioxidant Activity, Free Radical Scavenging Potential and Chemical Composition of Litsea cubeba Essential Oil"", 《JOURNAL OF ESSENTIAL OIL BEARING PLANTS》 * |
| 姚小丽: ""辣木叶总黄酮对酪氨酸酶的抑制及抗氧化活性研究"", 《生物化工》 * |
| 张善添 等: ""辣木叶总黄酮提取工艺的研究"", 《广东化工》 * |
| 杨彤: "《美容药物学》", 30 April 2007, 中国医药科技出版社 * |
| 樊新荣 等: "《四季芳疗养生手册》", 31 July 2014, 中医古籍出版社 * |
| 王福彦: "《吃出健康的智慧：饮食金钥匙》", 31 October 2013, 人民军医出版社 * |
| 顾奎琴: "《职业女性的饮食指南》", 30 September 2007, 金盾出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110464662A (en) * | 2019-09-04 | 2019-11-19 | 朱梅年 | A kind of freckle-removing beauty cream and preparation method thereof |
| CN111012687A (en) * | 2019-12-31 | 2020-04-17 | 中山大学新华学院 | Compound fisetin microemulsion gel and preparation method and application thereof |
| CN112972332A (en) * | 2021-03-03 | 2021-06-18 | 李培丰 | Rose whitening essence and preparation method thereof |
| CN112972332B (en) * | 2021-03-03 | 2022-04-22 | 爱花爱美(北京)生物科技有限公司 | Rose whitening essence and preparation method thereof |
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| CN108852937B (en) | 2021-03-23 |
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