CN107569441A - A kind of antiallergic lightening compositions and its application - Google Patents

A kind of antiallergic lightening compositions and its application Download PDF

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Publication number
CN107569441A
CN107569441A CN201710838459.2A CN201710838459A CN107569441A CN 107569441 A CN107569441 A CN 107569441A CN 201710838459 A CN201710838459 A CN 201710838459A CN 107569441 A CN107569441 A CN 107569441A
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China
Prior art keywords
extract
antiallergic
stem cell
pearl powder
chinese rose
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CN201710838459.2A
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Chinese (zh)
Inventor
葛啸虎
陈海佳
王飞
王一飞
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Priority to CN201710838459.2A priority Critical patent/CN107569441A/en
Publication of CN107569441A publication Critical patent/CN107569441A/en
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  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention discloses a kind of antiallergic lightening compositions, and it is consisted of the following composition:Chinese rose stem cell, Flos Caryophylli extract, pearl powder, Radix Et Rhizoma Nardostachyos extract, flat leaf Vanilla annamica berry extract, the pearl powder are Nano pearl powder, and the Flos Caryophylli extract is alcohol extracting thing, and the Radix Et Rhizoma Nardostachyos extract is alcohol extracting thing.The antiallergic lightening compositions of the present invention are made up of Chinese rose stem cell, Nano pearl powder, Flos Caryophylli extract, flat leaf Vanilla annamica berry extract and Radix Et Rhizoma Nardostachyos extract, wherein, the combination of both Chinese rose stem cell and Nano pearl powder can produce cooperative effect, have whitening, the synergistic function of nti-freckle.Meanwhile Flos Caryophylli extract, the combination of flat leaf Vanilla annamica berry extract and Radix Et Rhizoma Nardostachyos extract three can also produce cooperative effect, there is antiallergic and oxidation resistant synergistic function.The antiallergic lightening compositions of the present invention have that good whitening effect, antiallergic are good, and it uses the active component of natural plants to be made, and gentle non-stimulated, skin sensitivity person is also applicable.

Description

A kind of antiallergic lightening compositions and its application
Technical field
The present invention relates to cosmetic field, more particularly to a kind of antiallergic lightening compositions and its application.
Background technology
And as the raising of people's living standard, skin care increasingly attract people's attention, various cosmetics, Skin care item have turned into articles for daily use essential in people's life.Whitening class Cosmetic Market is increasingly active, production marketing with Day all increasings, it has also become one of main flow kind of skin protection cosmetics.Relevant whitening, whitening agent, whitening evaluation, lightening mechanism etc. Research deepen continuously, caused lot of domestic and foreign scientific research institution and the extensive concern of manufacturer.
Bright and clean, pale, ruddy skin is always the beauty prevailing custom that Nails are pursued, it is desirable to reach " skin such as snow, it is solidifying Such as fat " effect.Conventional people often cover raw material using whitening product containing a kind of physics of titanium dioxide, can be with temporary whitening Modify the skin of oneself.With the development of science and technology the whitening that today, women pursued has deeper physiological demand, pursue Overall skin it is pale, desalination such as color spot, dispel and prevent pigmented generation, while require that whitening product has peace Entirely, gently, efficient performance.But with a large amount of uses of cosmetics, while cosmetics make one to become " beautiful ", also bring The problem of noticeable, disease of skin also rolls up because of caused by cosmetics, and allergic is exactly wherein extremely common It is a kind of.Such as cosmetics cause skin it is red, it is swollen, hot, itch, pain, allergy of getting blister problem, not only can not find U.S. sensation, it is awkward A word used for translation but occurs often.
The content of the invention
The purpose of the present invention is the shortcomings that being directed to above-mentioned prior art, there is provided a kind of antiallergic lightening compositions and its application. The antiallergic lightening compositions of the present invention are made of natural component, have good antiallergic whitening effect, gentle non-stimulated.
To reach its purpose, the technical solution adopted in the present invention is:
A kind of antiallergic lightening compositions, its composition include Chinese rose stem cell.Chinese rose stem cell contains more than China rose Flavone compound, phenolic acid compound isoreactivity composition, the Chinese rose stem cell after broken wall can successfully convey active component To skin, and easily it is not only able to play a part of whitening, Kohakuhi by percutaneous absorption, also with splendid moisturizing, anti-ageing The effect of old.
Preferably, the composition of the antiallergic lightening compositions is also comprising Flos Caryophylli extract, pearl powder, Radix Et Rhizoma Nardostachyos extract, flat Leaf Vanilla annamica berry extract, the pearl powder are Nano pearl powder, and the Flos Caryophylli extract is alcohol extracting thing, the rhizoma nardostachyos extraction Thing is alcohol extracting thing.
Containing eugenol, syringyl alcohol, anisole in the alcohol extracting thing of cloves, there is antibacterial, anti-inflammatory and other effects.
Flat leaf Vanilla annamica berry extract is the water extract of flat leaf Vanilla annamica fruit, and it contains high-efficiency antioxidant agent catechin, energy Free radical is eliminated, improves skin oxidation resistance, skin pigmentation is reduced, delay skin aging, suppresses metalloproteinases Activity, while there is certain convergence and moisture-keeping efficacy, moreover it is possible to effectively suppress the growth of microorganism, suppression causes human skin sick Germ.
The various trace elements such as contained iron, zinc, manganese, selenium, copper can pass through gap and the gland of skin surface cell in pearl Body is improved skin nutrition and circulation, regulation acid-base scale of skin and enhancing Skin Cell elasticity etc. and made by dermal absorption so as to play With.Pearl can be with the activity of enhancement of SOD, and SOD has removing free radical, the function of skin whitening.By dermal absorption in pearl Working substance can slow down the transformation and oxidation of junket ammonia enzyme, improved melanin pigmentation, play whitening, the effect of nti-freckle.
The alcohol extracting thing of rhizoma nardostachyos contains substantial amounts of general flavone and polyphenol, has good antioxidation activity.
By creative experiments, the inventors discovered that, the combination of both Chinese rose stem cell and Nano pearl powder can produce collaboration Effect, there is whitening, the synergistic function of nti-freckle.Meanwhile Flos Caryophylli extract, flat leaf Vanilla annamica berry extract and rhizoma nardostachyos extraction The combination of thing three can also produce cooperative effect, have antiallergic and oxidation resistant synergistic function.Moreover, Chinese rose stem cell, Nano pearl powder, Flos Caryophylli extract, flat leaf Vanilla annamica berry extract and Radix Et Rhizoma Nardostachyos extract have good compatibility between each other.
Preferably, described antiallergic lightening compositions are made up of the composition of following percentage by weight:1~7% Chinese rose does Cell, 10~30% Flos Caryophylli extract, 15~45% pearl powder, 8~20% Radix Et Rhizoma Nardostachyos extract, 8~25% flat leaf Vanilla annamica berry extract.
Preferably, described antiallergic lightening compositions are made up of the composition of following percentage by weight:2~4% Chinese rose does Cell, 20~28% Flos Caryophylli extract, 30~40% pearl powder, 18~20% Radix Et Rhizoma Nardostachyos extract, 18~22% it is flat Leaf Vanilla annamica berry extract.
Preferably, described antiallergic lightening compositions are made up of the composition of following percentage by weight:3% Chinese rose is dry thin Born of the same parents, 25% Flos Caryophylli extract, 35% pearl powder, 17% Radix Et Rhizoma Nardostachyos extract, 20% flat leaf Vanilla annamica berry extract.
Further, the preparation method of the Chinese rose stem cell is:The newborn branch of Chinese rose is taken, surface sterilizing, peels off wood Matter portion, being organized on isolation medium after 25~30d of culture containing forming layer, bast, cortex and epidermis will be obtained, it is newborn Forming layer stem cell separated with the callus of dedifferentiation, the forming layer stem cell of acquisition is transferred on growth medium and trained Support, obtain Chinese rose stem cell.
A kind of antiallergic Skin whitening care cosmeticses, contain antiallergic lightening compositions of the present invention.
The antiallergic lightening compositions of the present invention conventional use of auxiliary agent of cosmetics that can arrange in pairs or groups is prepared into the skin cares of various formulations Product, such as facial mask, face cream, skin cream, toner.
Compared with prior art, beneficial effects of the present invention are:The present invention antiallergic lightening compositions by Chinese rose stem cell, Nano pearl powder, Flos Caryophylli extract, flat leaf Vanilla annamica berry extract and Radix Et Rhizoma Nardostachyos extract composition, wherein, Chinese rose stem cell and receive The combination of both rice pearl powder can produce cooperative effect, have whitening, the synergistic function of nti-freckle.It is meanwhile Flos Caryophylli extract, flat The combination of leaf Vanilla annamica berry extract and Radix Et Rhizoma Nardostachyos extract three can also produce cooperative effect, have antiallergic and oxidation resistant collaboration Synergistic effect.The antiallergic lightening compositions of the present invention have that good whitening effect, antiallergic are good, and it uses the work of natural plants Property composition be made, gentle non-stimulated, skin sensitivity person is also applicable.
Embodiment
More clearly to state technical scheme, further illustrate, but can not use with reference to specific embodiment In the limitation present invention, this is only the section Example of the present invention.
Embodiment 1
Embodiments of the invention provide a kind of antiallergic lightening compositions, and the antiallergic lightening compositions are by following weight percent The composition composition of ratio:3% Chinese rose stem cell, 25% Flos Caryophylli extract, 35% Nano pearl powder, the extraction of 17% rhizoma nardostachyos Thing, 20% flat leaf Vanilla annamica berry extract.
Embodiment 2
Embodiments of the invention provide a kind of antiallergic lightening compositions, and the antiallergic lightening compositions are by following weight percent The composition composition of ratio:2% Chinese rose stem cell, 20% Flos Caryophylli extract, 40% Nano pearl powder, the extraction of 20% rhizoma nardostachyos Thing, 18% flat leaf Vanilla annamica berry extract.
Embodiment 3
Embodiments of the invention provide a kind of antiallergic lightening compositions, and the antiallergic lightening compositions are by following weight percent The composition composition of ratio:4% Chinese rose stem cell, 28% Flos Caryophylli extract, 31% Nano pearl powder, the extraction of 15% rhizoma nardostachyos Thing, 22% flat leaf Vanilla annamica berry extract.
Embodiment 4
Embodiments of the invention provide a kind of antiallergic lightening compositions, and the antiallergic lightening compositions are by following weight percent The composition composition of ratio:1% Chinese rose stem cell, 30% Flos Caryophylli extract, 45% Nano pearl powder, the extraction of 16% rhizoma nardostachyos Thing, 8% flat leaf Vanilla annamica berry extract.
Embodiment 5
Embodiments of the invention provide a kind of antiallergic lightening compositions, and the antiallergic lightening compositions are by following weight percent The composition composition of ratio:7% Chinese rose stem cell, 10% Flos Caryophylli extract, 38% Nano pearl powder, the extraction of 20% rhizoma nardostachyos Thing, 25% flat leaf Vanilla annamica berry extract.
Embodiment 6
Embodiments of the invention provide a kind of antiallergic lightening compositions, and the antiallergic lightening compositions are by following weight percent The composition composition of ratio:7% Chinese rose stem cell, 30% Flos Caryophylli extract, 30% Nano pearl powder, the extraction of 8% rhizoma nardostachyos Thing, 25% flat leaf Vanilla annamica berry extract.
Embodiment 7
Embodiments of the invention provide a kind of antiallergic lightening compositions, and the antiallergic lightening compositions are by following weight percent The composition composition of ratio:7% Chinese rose stem cell, 30% Flos Caryophylli extract, 18% Nano pearl powder, the extraction of 20% rhizoma nardostachyos Thing, 25% flat leaf Vanilla annamica berry extract.
Embodiment 8
The preparation method of the Chinese rose stem cell of embodiment 1~7 is:The newborn branch of Chinese rose is taken, surface sterilizing, peels off wood Matter portion, being organized on isolation medium after 25~30d of culture containing forming layer, bast, cortex and epidermis will be obtained, it is newborn Forming layer stem cell separated with the callus of dedifferentiation, the forming layer stem cell of acquisition is transferred on growth medium and trained Support, obtain Chinese rose stem cell.
Test example
The antiallergic lightening compositions of embodiment 1~7 and appropriate amount of deionized water are tuned into the facial mask liquid of pasty state.
1. skin irritation test
40 volunteers of random selection, divide and be divided into 8 groups, wherein 7 groups of antiallergics tried out respectively with embodiment 1~7 Facial mask liquid made of lightening compositions, remaining 1 group uses deionized water as control.
Test method:Facial mask liquid or deionized water are coated on to the inboard arm skin of volunteer, observe 30min, Again facial mask liquid is cleaned with clear water.It is observed that the coating facial mask liquid of all volunteers or the skin of deionized water be showed no it is red Swollen, no fash, no varicella occurs.
2. whitening effect is tested
50 volunteers of 25~45 years old are selected, are randomly divided into 10 groups, every group of 5 people.
Comparative example 1:A kind of composition, it is made up of the composition of following percentage by weight:25% Flos Caryophylli extract, 38% Nano pearl powder, 37% flat leaf Vanilla annamica berry extract.
Comparative example 2:A kind of composition, it is made up of the composition of following percentage by weight:3% Chinese rose stem cell, 42% Radix Et Rhizoma Nardostachyos extract, 55% flat leaf Vanilla annamica berry extract.
Comparative example 3:A kind of composition, it is made up of the composition of following percentage by weight:3% Chinese rose stem cell, 55% Flos Caryophylli extract, 42% flat leaf Vanilla annamica berry extract.
The composition of comparative example 1~3 and appropriate amount of deionized water are tuned into the facial mask liquid of pasty state.
10 groups of volunteers are made with following arrange:7 groups of volunteers use beautiful with the antiallergic of embodiment 1~7 respectively Facial mask liquid made of white composition, 3 groups of volunteers use with facial mask liquid made of the composition of comparative example 1~3 respectively.
Test method:All volunteers are tested using half face, the whitening effect of the face of test comparison half.By facial mask liquid Sample is equably applied to half of subject on the face, after film liquid is dried behind 15~20min, is cleaned up with clear water.Experiment Cycle is two weeks, sooner or later each to smear once, during experiment, forbids subject to use other Skin whitening care cosmeticses.
Test evaluation standard:
Whitening effect is notable:Tested half face substantially bleaches, skin-tightening water profit;
Whitening effect is preferable:Tested half face bleaches, skin-tightening water profit;
Whitening effect is general:Tested half face becomes bright, and without substantially bleaching, skin water moistens;
Without whitening effect:Tested half face does not bleach, and also deepens without black.
Antiallergic effect is preferable:During experiment, tested half face is without appearance redness, itch, fash phenomenon.
It is general without antiallergic effect:During experiment, tested half face occurs redness, itch, fash phenomenon.
Result of the test is shown in Table one.
Table one
As shown in Table 1, have with facial mask liquid made of the antiallergic lightening compositions of the embodiment of the present invention 1~7 preferably beautiful Bai Kangmin effects, wherein best with antiallergic lightening compositions effect of embodiment 1.From the use result of comparative example 1~3, When lacking Chinese rose stem cell or Flos Caryophylli extract in composition, its whitening effect is decreased obviously;When lacking nanometer in composition When pearl powder or Radix Et Rhizoma Nardostachyos extract or flat leaf Vanilla annamica berry extract, its antiallergic positive effect declines.
Finally it should be noted that:The above embodiments are merely illustrative of the technical scheme of the present invention and are not intended to be limiting thereof, to the greatest extent The present invention is described in detail with reference to above-described embodiment for pipe, those of ordinary skills in the art should understand that:Still The embodiment of the present invention can be modified or equivalent substitution, and without departing from any of spirit and scope of the invention Modification or equivalent substitution, it all should cover among scope of the presently claimed invention.

Claims (7)

  1. A kind of 1. antiallergic lightening compositions, it is characterised in that:Composition includes Chinese rose stem cell.
  2. 2. antiallergic lightening compositions as claimed in claim 1, it is characterised in that:Composition also comprising Flos Caryophylli extract, pearl powder, Radix Et Rhizoma Nardostachyos extract, flat leaf Vanilla annamica berry extract, the pearl powder are Nano pearl powder, and the Flos Caryophylli extract is alcohol extracting Thing, the Radix Et Rhizoma Nardostachyos extract are alcohol extracting thing.
  3. 3. antiallergic lightening compositions as claimed in claim 2, it is characterised in that:It is made up of the composition of following percentage by weight:1 ~7% Chinese rose stem cell, 10~30% Flos Caryophylli extract, 18~45% pearl powder, 8~20% Radix Et Rhizoma Nardostachyos extract, 8 ~25% flat leaf Vanilla annamica berry extract.
  4. 4. antiallergic lightening compositions as claimed in claim 3, it is characterised in that:It is made up of the composition of following percentage by weight:2 ~4% Chinese rose stem cell, 20~28% Flos Caryophylli extract, 30~40% pearl powder, 15~20% Radix Et Rhizoma Nardostachyos extract, 18~22% flat leaf Vanilla annamica berry extract.
  5. 5. antiallergic lightening compositions as claimed in claim 4, it is characterised in that:It is made up of the composition of following percentage by weight: 3% Chinese rose stem cell, 25% Flos Caryophylli extract, 35% pearl powder, 17% Radix Et Rhizoma Nardostachyos extract, 20% flat leaf perfume (or spice) fruit Blue berry extract.
  6. 6. the antiallergic lightening compositions as described in any one of claim 1 to 5, it is characterised in that:The system of the Chinese rose stem cell Preparation Method is:Take the newborn branch of Chinese rose, surface sterilizing, peel off xylem, will obtain containing forming layer, bast, cortex and Epidermis is organized on isolation medium after 25~30d of culture, the callus point of newborn forming layer stem cell and dedifferentiation From, the forming layer stem cell of acquisition is transferred on growth medium and cultivated, acquisition Chinese rose stem cell.
  7. A kind of 7. antiallergic Skin whitening care cosmeticses, it is characterised in that:Contain the antiallergic whitening group as described in any one of claim 1 to 6 Compound.
CN201710838459.2A 2017-09-15 2017-09-15 A kind of antiallergic lightening compositions and its application Withdrawn CN107569441A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108670932A (en) * 2018-07-29 2018-10-19 佛山文森特知识产权服务有限公司 A kind of Haircare composition of anti-dandruff and itching-relieving
CN110652475A (en) * 2018-06-29 2020-01-07 伽蓝(集团)股份有限公司 Application of nardostachys chinensis extract
CN112293250A (en) * 2019-08-02 2021-02-02 伽蓝(集团)股份有限公司 Culture method of nardostachys chinensis callus cells
KR102261434B1 (en) * 2020-11-16 2021-06-07 주식회사 엑소코바이오 A whitening cosmetic composition comprising an exosome derived from Rosa stem cell as an active ingredient

Citations (1)

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CN105748343A (en) * 2016-02-25 2016-07-13 广州市科玮生物技术有限公司 Natural plant extract composition and application thereof in cosmetics

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Publication number Priority date Publication date Assignee Title
CN105748343A (en) * 2016-02-25 2016-07-13 广州市科玮生物技术有限公司 Natural plant extract composition and application thereof in cosmetics

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王建新等: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110652475A (en) * 2018-06-29 2020-01-07 伽蓝(集团)股份有限公司 Application of nardostachys chinensis extract
CN108670932A (en) * 2018-07-29 2018-10-19 佛山文森特知识产权服务有限公司 A kind of Haircare composition of anti-dandruff and itching-relieving
CN112293250A (en) * 2019-08-02 2021-02-02 伽蓝(集团)股份有限公司 Culture method of nardostachys chinensis callus cells
CN112293250B (en) * 2019-08-02 2023-02-17 伽蓝(集团)股份有限公司 Culture method of nardostachys chinensis callus cells
KR102261434B1 (en) * 2020-11-16 2021-06-07 주식회사 엑소코바이오 A whitening cosmetic composition comprising an exosome derived from Rosa stem cell as an active ingredient

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Application publication date: 20180112