CN1088064C - 萘并噁嗪衍生物、其制备方法及含有它们的药物组合物 - Google Patents
萘并噁嗪衍生物、其制备方法及含有它们的药物组合物 Download PDFInfo
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- CN1088064C CN1088064C CN98119987A CN98119987A CN1088064C CN 1088064 C CN1088064 C CN 1088064C CN 98119987 A CN98119987 A CN 98119987A CN 98119987 A CN98119987 A CN 98119987A CN 1088064 C CN1088064 C CN 1088064C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9710852A FR2767825A1 (fr) | 1997-09-01 | 1997-09-01 | Nouvelles trans-3,4,4a,5,6,10b-hexahydro-2h-napht°1,2-b!-1, 4-oxazines disubstituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR9710852 | 1997-09-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1222516A CN1222516A (zh) | 1999-07-14 |
| CN1088064C true CN1088064C (zh) | 2002-07-24 |
Family
ID=9510643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98119987A Expired - Fee Related CN1088064C (zh) | 1997-09-01 | 1998-08-31 | 萘并噁嗪衍生物、其制备方法及含有它们的药物组合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6025356A (OSRAM) |
| EP (1) | EP0899267B1 (OSRAM) |
| JP (1) | JP4417451B2 (OSRAM) |
| CN (1) | CN1088064C (OSRAM) |
| AT (1) | ATE229513T1 (OSRAM) |
| AU (1) | AU740928C (OSRAM) |
| BR (1) | BR9803933A (OSRAM) |
| CA (1) | CA2246482C (OSRAM) |
| DE (1) | DE69810034T2 (OSRAM) |
| DK (1) | DK0899267T3 (OSRAM) |
| ES (1) | ES2189108T3 (OSRAM) |
| FR (1) | FR2767825A1 (OSRAM) |
| HU (1) | HU226059B1 (OSRAM) |
| NO (1) | NO311218B1 (OSRAM) |
| NZ (1) | NZ331637A (OSRAM) |
| PL (1) | PL194533B1 (OSRAM) |
| PT (1) | PT899267E (OSRAM) |
| ZA (1) | ZA987963B (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0130219D0 (en) * | 2001-12-18 | 2002-02-06 | Pfizer Ltd | Compounds for the treatment of sexual dysfunction |
| MXPA05002331A (es) * | 2002-08-30 | 2005-08-18 | Biostratum Inc | Inhibidores de productos terminales de glicacion avanzada post-amadori. |
| MXPA05011225A (es) * | 2003-04-18 | 2005-12-14 | Pharmacia & Upjohn Co Llc | Politerapias. |
| FR2906249B1 (fr) * | 2006-09-26 | 2008-12-19 | Servier Lab | Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP2098511A1 (en) | 2008-03-07 | 2009-09-09 | Solvias AG | Process for preparing compounds containing a hydronaphtalene structure with an unsymmetrically substituted benzene ring |
| EP2303851A1 (en) * | 2008-06-27 | 2011-04-06 | H. Lundbeck A/S | Novel phenolic and catecholic amines and prodrugs thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991019719A1 (en) * | 1990-06-15 | 1991-12-26 | Whitby Research, Inc. | Substituted naphthoxazines useful as dopaminergics |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1204745A (en) * | 1981-11-20 | 1986-05-20 | Merck Co. | Hexahydronaphth (1,2-b) -1,4 -oxazines |
| US4420480A (en) * | 1981-11-20 | 1983-12-13 | Merck & Co., Inc. | Hexahydronaphth[1,2-b]-1,4-oxazines |
| US4540691A (en) * | 1984-04-13 | 1985-09-10 | Nelson Research & Development Co. | Dopamine agonists and use thereof |
| US5486611A (en) * | 1989-07-13 | 1996-01-23 | The Upjohn Company | Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives |
-
1997
- 1997-09-01 FR FR9710852A patent/FR2767825A1/fr active Pending
-
1998
- 1998-08-31 NO NO19984007A patent/NO311218B1/no not_active IP Right Cessation
- 1998-08-31 PL PL328285A patent/PL194533B1/pl not_active IP Right Cessation
- 1998-08-31 US US09/144,025 patent/US6025356A/en not_active Expired - Lifetime
- 1998-08-31 BR BR9803933-4A patent/BR9803933A/pt not_active Application Discontinuation
- 1998-08-31 NZ NZ331637A patent/NZ331637A/xx not_active IP Right Cessation
- 1998-08-31 CA CA002246482A patent/CA2246482C/fr not_active Expired - Fee Related
- 1998-08-31 HU HU9801951A patent/HU226059B1/hu not_active IP Right Cessation
- 1998-08-31 CN CN98119987A patent/CN1088064C/zh not_active Expired - Fee Related
- 1998-09-01 DE DE69810034T patent/DE69810034T2/de not_active Expired - Lifetime
- 1998-09-01 DK DK98402155T patent/DK0899267T3/da active
- 1998-09-01 ES ES98402155T patent/ES2189108T3/es not_active Expired - Lifetime
- 1998-09-01 EP EP98402155A patent/EP0899267B1/fr not_active Expired - Lifetime
- 1998-09-01 ZA ZA987963A patent/ZA987963B/xx unknown
- 1998-09-01 AU AU83024/98A patent/AU740928C/en not_active Ceased
- 1998-09-01 PT PT98402155T patent/PT899267E/pt unknown
- 1998-09-01 JP JP24691098A patent/JP4417451B2/ja not_active Expired - Fee Related
- 1998-09-01 AT AT98402155T patent/ATE229513T1/de active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991019719A1 (en) * | 1990-06-15 | 1991-12-26 | Whitby Research, Inc. | Substituted naphthoxazines useful as dopaminergics |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA987963B (en) | 1999-03-04 |
| HU226059B1 (en) | 2008-04-28 |
| PL194533B1 (pl) | 2007-06-29 |
| DK0899267T3 (da) | 2003-03-10 |
| EP0899267B1 (fr) | 2002-12-11 |
| EP0899267A1 (fr) | 1999-03-03 |
| DE69810034D1 (de) | 2003-01-23 |
| JPH11130759A (ja) | 1999-05-18 |
| ATE229513T1 (de) | 2002-12-15 |
| JP4417451B2 (ja) | 2010-02-17 |
| DE69810034T2 (de) | 2003-08-14 |
| HUP9801951A2 (hu) | 2000-02-28 |
| AU8302498A (en) | 1999-03-11 |
| HU9801951D0 (en) | 1998-11-30 |
| AU740928C (en) | 2002-05-16 |
| CN1222516A (zh) | 1999-07-14 |
| US6025356A (en) | 2000-02-15 |
| NO984007D0 (no) | 1998-08-31 |
| NZ331637A (en) | 1999-07-29 |
| BR9803933A (pt) | 2001-04-24 |
| AU740928B2 (en) | 2001-11-15 |
| ES2189108T3 (es) | 2003-07-01 |
| HUP9801951A3 (en) | 2000-04-28 |
| CA2246482C (fr) | 2002-11-26 |
| PT899267E (pt) | 2003-04-30 |
| NO311218B1 (no) | 2001-10-29 |
| HK1020340A1 (en) | 2000-04-14 |
| CA2246482A1 (fr) | 1999-03-01 |
| NO984007L (no) | 1999-03-02 |
| FR2767825A1 (fr) | 1999-02-26 |
| PL328285A1 (en) | 1999-03-15 |
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
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Granted publication date: 20020724 Termination date: 20120831 |