CN108779161A - 重定向t细胞以治疗hiv感染的方法 - Google Patents

重定向t细胞以治疗hiv感染的方法 Download PDF

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CN108779161A
CN108779161A CN201680066602.4A CN201680066602A CN108779161A CN 108779161 A CN108779161 A CN 108779161A CN 201680066602 A CN201680066602 A CN 201680066602A CN 108779161 A CN108779161 A CN 108779161A
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cells
acid sequence
hiv
nucleic acid
domain
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J·L·瑞利
R·雷曼
A·S·佩妮
C·T·艾利布雷特
M·C·麦隆
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University of Pennsylvania Penn
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CN201680066602.4A 2015-09-22 2016-09-22 重定向t细胞以治疗hiv感染的方法 Pending CN108779161A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562222132P 2015-09-22 2015-09-22
US62/222,132 2015-09-22
US201562253790P 2015-11-11 2015-11-11
US62/253,790 2015-11-11
PCT/US2016/053097 WO2017053556A1 (en) 2015-09-22 2016-09-22 Method of redirecting t cells to treat hiv infection

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AU (1) AU2016326500A1 (enExample)
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CN110343175A (zh) * 2019-06-26 2019-10-18 深圳市再生之城生物医药技术有限公司 抑制HIV-1病毒感染的scFv序列及其应用
CN110358793A (zh) * 2019-05-30 2019-10-22 南京艾德免疫治疗研究院有限公司 一种用于car-t制备的慢病毒载体制备方法
WO2023125822A1 (zh) * 2021-12-31 2023-07-06 北京三诺佳邑生物技术有限责任公司 靶向hiv感染细胞的嵌合抗原受体t细胞

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CN108779161A (zh) * 2015-09-22 2018-11-09 宾夕法尼亚大学董事会 重定向t细胞以治疗hiv感染的方法
ES2894304T3 (es) 2015-10-25 2022-02-14 Sanofi Sa Proteínas de unión triespecíficas y/o trivalentes para la prevención o tratamiento de infección por VIH
WO2017139065A1 (en) 2016-02-08 2017-08-17 American Gene Technologies International Inc. Hiv vaccination and immunotherapy
TWI788286B (zh) 2016-04-13 2023-01-01 法商賽諾菲公司 三特異性和/或三價結合蛋白
EP4257193A3 (en) 2016-04-13 2024-01-24 Sanofi Trispecific and/or trivalent binding proteins
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US20200061117A1 (en) * 2017-05-08 2020-02-27 The Regents Of The University Of California Protective Chimeric Antigen Receptor Stem Cell Gene Therapy for Viral Infection
KR102508182B1 (ko) * 2017-05-17 2023-03-09 썬더 바이오테크 인크. 형질전환 대식세포, 키메라 항원 수용체, 및 관련 방법
US10415017B2 (en) 2017-05-17 2019-09-17 Thunder Biotech, Inc. Transgenic macrophages, chimeric antigen receptors, and associated methods
US12496338B2 (en) 2017-10-23 2025-12-16 City Of Hope CAR for treatment of HIV infection
CN108059675B (zh) * 2017-12-12 2021-09-10 武汉波睿达生物科技有限公司 重组pg9-car分子的构建及其在清除hiv-1感染细胞中的应用
KR20210031898A (ko) 2018-07-13 2021-03-23 난징 레전드 바이오테크 씨오., 엘티디. 전염병을 치료하기 위한 공동수용체 시스템
MX2021009020A (es) * 2019-01-28 2021-09-28 Xyphos Biosciences Inc Ligandos nkg2d no naturales modificados que entregan selectivamente moleculas heterologas unidas a receptores nkg2d no naturales en celulas car.
US11613576B2 (en) 2019-04-09 2023-03-28 Sanofi Trispecific binding proteins, methods, and uses thereof
EP3980453A4 (en) * 2019-06-07 2023-07-05 The Trustees of the University of Pennsylvania Dual car expressing t cells individually linked to cd28 and 4-1bb
KR20220150320A (ko) * 2020-03-03 2022-11-10 아메리칸 진 테크놀로지스 인터내셔널 인코포레이티드 Hiv 치료를 위한 림프구에서 외생성 인자의 주문형 발현

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