CN108721174A - A kind of anti-aging skin care product and preparation method thereof of addition Fructus Cannabis extract - Google Patents

A kind of anti-aging skin care product and preparation method thereof of addition Fructus Cannabis extract Download PDF

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CN108721174A
CN108721174A CN201810974681.XA CN201810974681A CN108721174A CN 108721174 A CN108721174 A CN 108721174A CN 201810974681 A CN201810974681 A CN 201810974681A CN 108721174 A CN108721174 A CN 108721174A
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extract
fructus cannabis
skin care
cannabis extract
aging
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项佳红
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication

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  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of anti-aging skin care products and preparation method thereof of addition Fructus Cannabis extract.The raw material of the skin care item includes natural constituent and auxiliary material, and the natural constituent is made of Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract and borneol.The anti-aging skin care product of above-mentioned addition Fructus Cannabis extract contains Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract and the borneol of specified weight part composition, by the proportioning dosage for controlling each component, each component is set to give full play to except respective basic effect, it can be synergistic, human endocrine is effectively adjusted, anti-aging is fundamentally played the role of.The skin care item have excellent anti-aging effects, and the crowd for being suitable for skin aging uses.

Description

A kind of anti-aging skin care product and preparation method thereof of addition Fructus Cannabis extract
Technical field
The present invention relates to cosmetic technical fields, more particularly to a kind of anti-aging skin care product of addition Fructus Cannabis extract And preparation method thereof.
Background technology
With the continuous improvement of living standard, people pursue the life of more high-quality, to the health of autologous skin Also more and more pay attention to, to also higher and higher to the quality requirement of cosmetics and skincare product.The aging of human body is the certainty of life growth Rule, wherein the variation with skin is the most apparent, skin aging refers to that skin surface is coarse and wrinkle occur.With the increasing at age Long, epidermal cell, sebaceous glands and the sweat gland of skin gradually fail, and normal function and activity also gradually weaken.Due to sebaceous glands It is reduced with sweat gland, subcutaneous layer of fat gradually aoxidizes thinning, and skin is caused to become dry and soft tarnish.Suffer from the people of Chronic Liver, kidney diaseases, And malnutritive, anaemia and chronic fatigue excessively, the people of insomnia, the phenomenon that also will appear skin early ageing.Anti-aging cosmetics Yi Zhan cosmetics sales main market players at present, most of product are all from the most important factor of skin aging:Photo-aging and from Started with by base, add such as superoxide dismutase (SOD), tocopherol acetate, ascorbic acid, retinol, hinders free radical Peroxide is formed, effect is relatively simple, while the problems such as there is also stabilitys poor, easy to change and allergy.Present is anti-aging Cosmetics some is in order to reach industrial components that good anti-aging effect has used inoxidizability strong, quick in short-term, still Use for a long time is done great harm to human body;The anti-aging cosmetics addition vitamins antioxidant having, but it is this kind of anti-oxidant Agent stability is poor.There to be the natural plant extracts of anti-aging effect that the good ingredient of stability is made to be added in cosmetics, assign The good anti-aging effect of product is given, is a trend of health care old product.
Invention content
The problem of cannot still meeting consumer demand in terms of anti-aging the effect of based on contemporary skin care product, the present invention provide A kind of anti-aging skin care product and preparation method thereof of addition Fructus Cannabis extract.
A kind of anti-aging skin care product of addition Fructus Cannabis extract, the raw materials of the skin care item include natural constituent with And auxiliary material;
The natural constituent is grouped as by the group of following parts by weight:
15~25 parts of Fructus Cannabis extract
10~20 parts of blackberry extract
6~8 parts of herba hedyotis diffusae extract
3~5 parts of borneol.
The anti-aging skin care product of above-mentioned addition Fructus Cannabis extract contains by Fructus Cannabis extract, blackberry extract, white flower The natural constituent of HERBA HEDYOTIS DIFFUSAE extract and borneol composition makes each component abundant by controlling the proportioning dosage of each component It plays except respective basic effect, can be synergistic, human endocrine is effectively adjusted, the work of anti-aging is fundamentally played With.The skin care item have excellent anti-aging effects, and the crowd for being suitable for skin aging uses.
In one of the embodiments, by weight percentage, the natural constituent adding in the skin care item Dosage is 2~3%.
In one of the embodiments, by weight percentage, the auxiliary material includes following components:
Glycerine 4~6%, butanediol 3~5%, glycerin monostearate 2.5~3.5%, isopropyl myristate 2~ 3%, collagen protein powder 1.5~2.5%, Steareth phosphoric acid ester sodium 1.2~1.6%, hyaluronic acid acid sodium Tocopherol acetate 1~1.5%, sodium carboxymethylcellulose 0.6~0.8%, triethanolamine 0.5~1.5%, jojoba oil 0.4 ~0.6%, Rosa Damascana 0.3~0.5%, essence 0.2~0.3% and deionized water surplus.
Present invention also provides the preparation methods of the anti-aging skin care product of above-mentioned addition Fructus Cannabis extract, by following steps Composition:
(1) by butanediol, Steareth phosphoric acid ester sodium, sodium carboxymethylcellulose, triethanolamine with it is sweet Oil mixing, stirs evenly to form dispersion liquid, then collagen protein powder is added in dispersion liquid, while adding deionized water, will mix It closes object and is heated with stirring to 70~80 DEG C, insulated and stirred 15~25 minutes obtains A phase intermediate products;
(2) by glycerin monostearate, isopropyl myristate, hyaluronic acid acid sodium tocopherol acetate, jojoba oil, Rosa Damascana mixes, and is heated with stirring to 75~85 DEG C, insulated and stirred 20~30 minutes obtains B phase intermediate products;
(3) under stirring, B phase intermediate products are slowly added into A phase intermediate products, at 80~90 DEG C according to 800~1200 revs/min of stir speed (S.S.) carries out a homogeneous, subsequent vacuum defoamation, and object temperature to be mixed is down to 48~50 DEG C When, natural constituent and essence is added, second homogenate, subsequent vacuum are carried out according to 600~800 revs/min of stir speed (S.S.)s Deaeration is cooled to room temperature, sampling Detection, and qualification discharging is to get finished product.
The raw material of the preparation method of above-mentioned skin care item is easy to get, is simple for process, is suitable for large-scale industrial production.
Fructus Cannabis extract, blackberry extract, oldenlandia in the natural constituent in one of the embodiments, The preparation method of careless extract is:Fructus cannabis, blackberry, blueberry, oldenlandia diffusa are crushed respectively and cross 200 mesh sieve, by what is respectively obtained Powder is added separately in the ethanol solution that mass concentration is 95%, is ultrasonically treated 15~20 minutes, and the frequency of ultrasonic wave is 30kHZ, the filtrate of collection, is placed in rotary evaporator by water-bath reflux 60~90 minutes after filtering at 75~85 DEG C, if It is -0.07~-0.1MPa to determine vacuum degree, is evaporated under reduced pressure under conditions of 50 DEG C, and Fructus Cannabis extract, blackberry, blueberry extraction are respectively obtained Object, herba hedyotis diffusae extract.
The time of a homogeneous is 8~10 minutes in the step (3) in one of the embodiments,.
The time of second homogenate is 3~5 minutes in the step (3) in one of the embodiments,.
Specific implementation mode
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, below in conjunction with specific implementation mode, The present invention will be described in further detail.It should be appreciated that the specific embodiments described herein are only used to explain this hair It is bright, it is not intended to limit the present invention.
Unless otherwise defined, all of technologies and scientific terms used here by the article and belong to the technical field of the present invention The normally understood meaning of technical staff is identical.Used term is intended merely to description tool in the description of the invention herein The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term " and or " used herein includes one or more Any and all combinations of relevant Listed Items.
Raw materials used and reagent is commercially available common raw material and reagent in following embodiment.
A kind of anti-aging skin care product of addition Fructus Cannabis extract, the raw materials of the skin care item include natural constituent with And auxiliary material;
The natural constituent is grouped as by the group of following parts by weight:
15~25 parts of Fructus Cannabis extract
10~20 parts of blackberry extract
6~8 parts of herba hedyotis diffusae extract
3~5 parts of borneol.
Wherein, fructus cannabis is dry mature seed also known as pockmarks, pockmarks benevolence, hempseed, the hemp of moraceae plants hemp Benevolence, hemp, winter pockmarks etc..Its property of fructus cannabis is sweet, flat, returns spleen, stomach, large intestine channel, have moisturize, laxation, treating stranguria, promoting blood circulation work With.Fructus cannabis is rich in grease, has blood pressure lowering, diuresis, analgesia, anti-inflammatory, antithrombus formation, treatment constipation, delays senility, improves Memory and other effects, long-term consumption have preferably chronic forms inflammation, paralysis, constipation, hypertension, hyperlipidemia and gynecological disease etc. Auxiliary curative effect, external application can have auxiliary curative effect to neurodermatitis.Also containing abundant protein, fructus cannabis in fructus cannabis It can improve nutrition, adjust blood glucose, promote brain development, enhance body fatigue resistance and immune function, and have certain anti-ageing Old effect.Simultaneously rich in various amino acid necessary to human body in fructus cannabis, therefore, the nutritive value with very abundant.
Wherein, the absorbable plant erythrocuprein of human body contained by blackberry, blueberry, abbreviation SOD.SOD is in vivo Horizontal height is aging and dead intuitive index.It is existing it has proven convenient that the disease caused by oxygen radical is up to more than 60 kind.It can be right It is anti-to be damaged caused by oxygen radical is cell with blocking, and damaged cell is repaired in time, it restores caused by free radical to thin Born of the same parents injure.SOD be ministry of Health of China approval with anti-aging, immunological regulation, adjust blood fat, radioresistance, cosmetology function object One of matter.
Wherein, oldenlandia diffusa is the herb of madder wort oldenlandia diffusa, first recorded in《Mingyi Bielu》, alias tang Grass, snake needle grass, short-foot white flower Hedyotis diffusa Willd, Herba Turczaninowiae Fastigiatae, Radix Picriae felterrae, crane tongue grass, waterplantain ottelia herb etc. are the civil common Chinese medicine in China Material.Pharmacological research shows that the medicine plays the role of antitumor, anti-inflammatory, antibacterial, enhancing immune function, and there is clearing heat and detoxicating, diuresis to disappear The effect of swollen, is used for acute appendicitis, sore furuncle poison, abscess of throat, venomous snake bite, damp and hot yellow subcutaneous ulcer, ephritis, hepatic sclerosis, early stage lymph node Core, stomatitis, difficult urination etc..
Wherein, borneol also known as piece brain, orange slices, L-Borneol, kapur, MEIHUA BINGPIAN, Dipterocarpus pilosus, plum blossom brain, borneol brain, Mei Bing etc. through steam distillation and is recrystallized and is obtained by composite family Blumea balsamifera cauline leaf or canella borneol camphor tree branches and leaves.Borneol taste It is pungent, bitter, it is slightly cold;The thoughts of returning home, liver, lung channel;Delicate fragrance a surname dissipate has the effect of inducing resuscitation of having one's ideas straightened out, heat-clearing dissipates poison, removing nebula, cures mainly heat Sick unconsciousness due to high fever, apoplexy coma due to blocking of the respiratory system shies epilepsy, summer-heat and damp blinds clear key, throat deafness, aphtha tooth swells, sore carbuncle infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid, red eye, swell pain, screen film Hide eyeball.
Above-mentioned natural constituent is made of Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract and borneol, By controlling the proportioning dosage of each component, makes each component on the basis of giving full play to respective effect, can further cooperate with Synergy.The natural constituent can effectively adjust human endocrine, fundamentally play the role of anti-aging, have excellent Anti-aging effects.
In a preferred embodiment, by weight percentage, the natural constituent is in the skin care item Additive amount is 2~3%.
In a preferred embodiment, by weight percentage, other described acceptable auxiliary materials include following components:
Glycerine 4~6%, butanediol 3~5%, glycerin monostearate 2.5~3.5%, isopropyl myristate 2~ 3%, collagen protein powder 1.5~2.5%, Steareth phosphoric acid ester sodium 1.2~1.6%, hyaluronic acid acid sodium Tocopherol acetate 1~1.5%, sodium carboxymethylcellulose 0.6~0.8%, triethanolamine 0.5~1.5%, jojoba oil 0.4 ~0.6%, Rosa Damascana 0.3~0.5%, essence 0.2~0.3% and deionized water surplus.
Present invention also provides the preparation methods of the anti-aging skin care product of above-mentioned addition Fructus Cannabis extract, by following steps Composition:
(1) by butanediol, Steareth phosphoric acid ester sodium, sodium carboxymethylcellulose, triethanolamine with it is sweet Oil mixing, stirs evenly to form dispersion liquid, then collagen protein powder is added in dispersion liquid, while adding deionized water, will mix It closes object and is heated with stirring to 70~80 DEG C, insulated and stirred 15~25 minutes obtains A phase intermediate products;
(2) by glycerin monostearate, isopropyl myristate, hyaluronic acid acid sodium tocopherol acetate, jojoba oil, Rosa Damascana mixes, and is heated with stirring to 75~85 DEG C, insulated and stirred 20~30 minutes obtains B phase intermediate products;
(3) under stirring, B phase intermediate products are slowly added into A phase intermediate products, at 80~90 DEG C according to 800~1200 revs/min of stir speed (S.S.) carries out a homogeneous, subsequent vacuum defoamation, and object temperature to be mixed is down to 48~50 DEG C When, natural constituent and essence is added, second homogenate, subsequent vacuum are carried out according to 600~800 revs/min of stir speed (S.S.)s Deaeration is cooled to room temperature, sampling Detection, and qualification discharging is to get finished product.
In a preferred embodiment, Fructus Cannabis extract, blackberry extract, long-noded pit viper in the natural constituent The preparation method of diffusa extract is:Fructus cannabis, blackberry, blueberry, oldenlandia diffusa are crushed to and crossed 200 mesh sieve respectively, will respectively be obtained Powder be added separately in the ethanol solution that mass concentration is 95%, be ultrasonically treated 15~20 minutes, the frequency of ultrasonic wave is 30kHZ, the filtrate of collection, is placed in rotary evaporator by water-bath reflux 60~90 minutes after filtering at 75~85 DEG C, if It is -0.07~-0.1MPa to determine vacuum degree, is evaporated under reduced pressure under conditions of 50 DEG C, and Fructus Cannabis extract, blackberry, blueberry extraction are respectively obtained Object, herba hedyotis diffusae extract.
In a preferred embodiment, the time of a homogeneous is 8~10 minutes in the step (3).
In a preferred embodiment, the time of second homogenate is 3~5 minutes in the step (3).
Below by embodiment, the present invention is furture elucidated.It should be pointed out that the present invention is not intended to be limited to the reality Apply example.
Embodiment 1
The formula of the skin care item of the present embodiment is as follows:
Natural constituent 2%, glycerine 4%, butanediol 3%, glycerin monostearate 2.5%, isopropyl myristate 2%, collagen protein powder 1.5%, Steareth phosphoric acid ester sodium 1.2%, hyaluronic acid acid sodium tocopheryl acetate Ester 1%, sodium carboxymethylcellulose 0.6%, triethanolamine 0.5%, jojoba oil 0.4%, Rosa Damascana 0.3%, essence 0.2% and deionized water surplus.
The natural constituent is grouped as by the group of following parts by weight:
15 parts of Fructus Cannabis extract
10 parts of blackberry extract
6 parts of herba hedyotis diffusae extract
3 parts of borneol.
The skin care item of the present embodiment are prepared in accordance with the following methods:
(1) by butanediol, Steareth phosphoric acid ester sodium, sodium carboxymethylcellulose, triethanolamine with it is sweet Oil mixing, stirs evenly to form dispersion liquid, then collagen protein powder is added in dispersion liquid, while adding deionized water, will mix It closes object and is heated with stirring to 70 DEG C, insulated and stirred 15 minutes obtains A phase intermediate products;
(2) by glycerin monostearate, isopropyl myristate, hyaluronic acid acid sodium tocopherol acetate, jojoba oil, Rosa Damascana mixes, and is heated with stirring to 75 DEG C, insulated and stirred 20 minutes obtains B phase intermediate products;
(3) under stirring, B phase intermediate products are slowly added into A phase intermediate products, according to 800 at 80 DEG C Rev/min stir speed (S.S.) carry out a homogeneous, time of a homogeneous is 8 minutes, subsequent vacuum defoamation, object temperature to be mixed When being down to 48 DEG C, natural constituent and essence is added, second homogenate is carried out according to 600 revs/min of stir speed (S.S.)s, it is secondary equal The time of matter is 3 minutes, and subsequent vacuum defoamation is cooled to room temperature, sampling Detection, and qualification discharging is denoted as A1 to get finished product.
The preparation method of Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract in the natural constituent For:Fructus cannabis, blackberry, blueberry, oldenlandia diffusa are crushed to and crossed 200 mesh sieve respectively, the powder respectively obtained is added separately to quality It in a concentration of 95% ethanol solution, is ultrasonically treated 15 minutes, the frequency of ultrasonic wave is 30kHZ, the water-bath reflux at 75 DEG C 60 minutes, the filtrate of collection is placed in rotary evaporator after filtering, sets vacuum degree as -0.07MPa, under conditions of 50 DEG C Vacuum distillation, respectively obtains Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract.
Embodiment 2
The formula of the skin care item of the present embodiment is as follows:
Natural constituent 2.5%, glycerine 5%, butanediol 4%, glycerin monostearate 3%, isopropyl myristate 2.5%, collagen protein powder 2%, Steareth phosphoric acid ester sodium 1.4%, hyaluronic acid acid sodium tocopheryl acetate Ester 1.25%, sodium carboxymethylcellulose 0.7%, triethanolamine 1%, jojoba oil 0.5%, Rosa Damascana 0.4%, essence 0.25% and deionized water surplus.
The natural constituent is grouped as by the group of following parts by weight:
20 parts of Fructus Cannabis extract
15 parts of blackberry extract
7 parts of herba hedyotis diffusae extract
4 parts of borneol.
The skin care item of the present embodiment are prepared in accordance with the following methods:
(1) by butanediol, Steareth phosphoric acid ester sodium, sodium carboxymethylcellulose, triethanolamine with it is sweet Oil mixing, stirs evenly to form dispersion liquid, then collagen protein powder is added in dispersion liquid, while adding deionized water, will mix It closes object and is heated with stirring to 75 DEG C, insulated and stirred 20 minutes obtains A phase intermediate products;
(2) by glycerin monostearate, isopropyl myristate, hyaluronic acid acid sodium tocopherol acetate, jojoba oil, Rosa Damascana mixes, and is heated with stirring to 80 DEG C, insulated and stirred 25 minutes obtains B phase intermediate products;
(3) under stirring, B phase intermediate products are slowly added into A phase intermediate products, according to 1000 at 85 DEG C Rev/min stir speed (S.S.) carry out a homogeneous, time of a homogeneous is 9 minutes, subsequent vacuum defoamation, object temperature to be mixed When being down to 49 DEG C, natural constituent and essence is added, second homogenate is carried out according to 700 revs/min of stir speed (S.S.)s, it is secondary equal The time of matter is 4 minutes, and subsequent vacuum defoamation is cooled to room temperature, sampling Detection, and qualification discharging is denoted as A2 to get finished product.
The preparation method of Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract in the natural constituent For:Fructus cannabis, blackberry, blueberry, oldenlandia diffusa are crushed to and crossed 200 mesh sieve respectively, the powder respectively obtained is added separately to quality It in a concentration of 95% ethanol solution, is ultrasonically treated 17 minutes, the frequency of ultrasonic wave is 30kHZ, the water-bath reflux at 80 DEG C 75 minutes, the filtrate of collection is placed in rotary evaporator after filtering, sets vacuum degree as -0.08MPa, under conditions of 50 DEG C Vacuum distillation, respectively obtains Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract.
Embodiment 3
The formula of the skin care item of the present embodiment is as follows:
Natural constituent 3%, glycerine 6%, butanediol 5%, glycerin monostearate 3.5%, isopropyl myristate 3%, collagen protein powder 2.5%, Steareth phosphoric acid ester sodium 1.6%, hyaluronic acid acid sodium tocopheryl acetate Ester 1.5%, sodium carboxymethylcellulose 0.8%, triethanolamine 1.5%, jojoba oil 0.6%, Rosa Damascana 0.5%, essence 0.3% and deionized water surplus.
The natural constituent is grouped as by the group of following parts by weight:
25 parts of Fructus Cannabis extract
20 parts of blackberry extract
8 parts of herba hedyotis diffusae extract
5 parts of borneol.
The skin care item of the present embodiment are prepared in accordance with the following methods:
(1) by butanediol, Steareth phosphoric acid ester sodium, sodium carboxymethylcellulose, triethanolamine with it is sweet Oil mixing, stirs evenly to form dispersion liquid, then collagen protein powder is added in dispersion liquid, while adding deionized water, will mix It closes object and is heated with stirring to 80 DEG C, insulated and stirred 25 minutes obtains A phase intermediate products;
(2) by glycerin monostearate, isopropyl myristate, hyaluronic acid acid sodium tocopherol acetate, jojoba oil, Rosa Damascana mixes, and is heated with stirring to 85 DEG C, insulated and stirred 30 minutes obtains B phase intermediate products;
(3) under stirring, B phase intermediate products are slowly added into A phase intermediate products, according to 1200 at 90 DEG C Rev/min stir speed (S.S.) carry out a homogeneous, time of a homogeneous is 10 minutes, subsequent vacuum defoamation, object temperature to be mixed When degree is down to 50 DEG C, natural constituent and essence is added, second homogenate is carried out according to 800 revs/min of stir speed (S.S.)s, it is secondary The time of homogeneous is 5 minutes, and subsequent vacuum defoamation is cooled to room temperature, sampling Detection, and qualification discharging is denoted as A3 to get finished product.
The preparation method of Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract in the natural constituent For:Fructus cannabis, blackberry, blueberry, oldenlandia diffusa are crushed to and crossed 200 mesh sieve respectively, the powder respectively obtained is added separately to quality It in a concentration of 95% ethanol solution, is ultrasonically treated 20 minutes, the frequency of ultrasonic wave is 30kHZ, the water-bath reflux at 85 DEG C 90 minutes, the filtrate of collection is placed in rotary evaporator after filtering, sets vacuum degree as -0.1MPa, under conditions of 50 DEG C Vacuum distillation, respectively obtains Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract.
Comparative example 1
The formula of the skin care item of this comparative example is with preparation method substantially with embodiment 1, and difference is, in natural constituent Fructus Cannabis extract is not added, final skin care item obtained are denoted as C1.
Comparative example 2
The formula of the skin care item of this comparative example is with preparation method substantially with embodiment 1, and difference is, in natural constituent Blackberry extract is not added, final skin care item obtained are denoted as C2.
Comparative example 3
The formula of the skin care item of this comparative example is with preparation method substantially with embodiment 1, and difference is, in natural constituent Herba hedyotis diffusae extract is not added, final skin care item obtained are denoted as C3.
Comparative example 4
The formula of the skin care item of this comparative example is with preparation method substantially with embodiment 1, and difference is, in natural constituent Borneol is not added, final skin care item obtained are denoted as C4.
Performance test
The present embodiment carries out performance test to the skin care item prepared by embodiment 1-3 and comparative example 1-4.
(1) experiment packet:Select the age at 40-50 Sui, the crowd that aging phenomenon occurs in skin is test object, at random It is divided into 7 groups, every group of 10 people, each group is in skin health, organism endocrine situation etc. there are no significant difference, 1-7 The skin care item C1-C4 that the skin care item A1-A3 and comparative example 1-4 that group is prepared using embodiment 1-3 respectively are prepared.
(2) application method of skin care item:
After conditioned water for skin to be treated is cleaned, takes appropriate skin care item at the palm of the hand, slightly rub, be uniformly applied to skin On.
(3) test result:
Comprehensive score is carried out using investigation point system.Smearing skin care item are primary before each group of people group sleeps daily, continuous to smear 3 Month, fill in grade form on probation.Every using effect total score is 10 points in grade form, and 9-10 points indicate that effect is optimal;6-8 points indicate Effect is preferable;4-5 points indicate that effect is general;3 points of following presentation effects are poor, every using effect average situation such as table 1 It is shown:
Table 1
Skin aging improves degree Pachylosis improves degree Skin irritatin degree of alleviation
A1 8.4 8.7 8.2
A2 8.6 8.8 8.1
A3 8.3 8.5 7.9
C1 5.7 8.6 8.0
C2 6.2 8.4 7.7
C3 4.9 8.7 8.3
C4 6.8 8.6 8.1
Test result is as shown above, pachylosis improves degree, skin irritatin degree of alleviation this two indexs are commented In point, the skin care item and the skin care item performance of comparative example C1-C4 groups of embodiment A1-A3 groups are not much different, this is because to above-mentioned The ingredient that two indexs play a crucial role not is natural constituent, but glycerine, isopropyl myristate, collagen protein powder etc. Auxiliary material.But during in skin aging improvement degree, this can embody the index of skin care item critical function of the present invention, embodiment A1-A3 groups Skin care item compared with the skin care item of comparative example C1-C4 groups, have significantly more effect.Illustrate the day of the skin care item of the present invention There is the facilitation mutually cooperateed between right active ingredient.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention Range.

Claims (7)

1. a kind of anti-aging skin care product of addition Fructus Cannabis extract, which is characterized in that the raw material of the skin care item includes natural Active ingredient and auxiliary material;
The natural constituent is grouped as by the group of following parts by weight:
15~25 parts of Fructus Cannabis extract
10~20 parts of blackberry extract
6~8 parts of herba hedyotis diffusae extract
3~5 parts of borneol.
2. the anti-aging skin care product of addition Fructus Cannabis extract according to claim 1, which is characterized in that with weight percent Than meter, additive amount of the natural constituent in the skin care item is 2~3%.
3. the anti-aging skin care product of addition Fructus Cannabis extract according to claim 2, which is characterized in that with weight percent Than meter, the auxiliary material includes following components:
Glycerine 4~6%, butanediol 3~5%, glycerin monostearate 2.5~3.5%, isopropyl myristate 2~3%, glue Former albumen powder 1.5~2.5%, Steareth phosphoric acid ester sodium 1.2~1.6%, hyaluronic acid acid sodium tocopherol Acetic acid esters 1~1.5%, sodium carboxymethylcellulose 0.6~0.8%, triethanolamine 0.5~1.5%, jojoba oil 0.4~ 0.6%, Rosa Damascana 0.3~0.5%, essence 0.2~0.3% and deionized water surplus.
4. a kind of preparation method of the anti-aging skin care product of addition Fructus Cannabis extract as claimed in claim 3, feature exist In comprising the steps of:
(1) butanediol, Steareth phosphoric acid ester sodium, sodium carboxymethylcellulose, triethanolamine and glycerine are mixed It closes, stirs evenly to form dispersion liquid, then collagen protein powder is added in dispersion liquid, while adding deionized water, by mixture 70~80 DEG C are heated with stirring to, insulated and stirred 15~25 minutes obtains A phase intermediate products;
(2) by glycerin monostearate, isopropyl myristate, hyaluronic acid acid sodium tocopherol acetate, jojoba oil, rose Essential oil mixes, and is heated with stirring to 75~85 DEG C, insulated and stirred 20~30 minutes obtains B phase intermediate products;
(3) under stirring, B phase intermediate products are slowly added into A phase intermediate products, according to 800 at 80~90 DEG C ~1200 revs/min of a stir speed (S.S.) homogeneous of progress, subsequent vacuum defoamation, when object temperature to be mixed is down to 48~50 DEG C, Natural constituent and essence is added, carries out second homogenate according to 600~800 revs/min of stir speed (S.S.)s, subsequent vacuum is de- Bubble, is cooled to room temperature, sampling Detection, and qualification discharging is to get finished product.
5. the preparation method of the anti-aging skin care product of addition Fructus Cannabis extract according to claim 4, which is characterized in that Fructus Cannabis extract in the natural constituent, blackberry extract, herba hedyotis diffusae extract preparation method be:Respectively will Fructus cannabis, blackberry, blueberry, oldenlandia diffusa crush and cross 200 mesh sieve, and the powder respectively obtained, which is added separately to mass concentration, is It in 95% ethanol solution, is ultrasonically treated 15~20 minutes, the frequency of ultrasonic wave is 30kHZ, the water-bath time at 75~85 DEG C The filtrate of collection, is placed in rotary evaporator by stream 60~90 minutes after filtering, sets vacuum degree as -0.07~-0.1MPa, in It is evaporated under reduced pressure under conditions of 50 DEG C, respectively obtains Fructus Cannabis extract, blackberry extract, herba hedyotis diffusae extract.
6. the preparation method of the anti-aging skin care product of addition Fructus Cannabis extract according to claim 4, which is characterized in that The time of a homogeneous is 8~10 minutes in the step (3).
7. the preparation method of the anti-aging skin care product of addition Fructus Cannabis extract according to claim 4, which is characterized in that The time of second homogenate is 3~5 minutes in the step (3).
CN201810974681.XA 2018-08-24 2018-08-24 A kind of anti-aging skin care product and preparation method thereof of addition Fructus Cannabis extract Pending CN108721174A (en)

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