CN109620779A - A kind of anti-acne moisturizing cosmetic face cream and preparation method thereof - Google Patents

A kind of anti-acne moisturizing cosmetic face cream and preparation method thereof Download PDF

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CN109620779A
CN109620779A CN201910121554.XA CN201910121554A CN109620779A CN 109620779 A CN109620779 A CN 109620779A CN 201910121554 A CN201910121554 A CN 201910121554A CN 109620779 A CN109620779 A CN 109620779A
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cosmetic face
face cream
acne
moisturizing cosmetic
revs
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陈伟伟
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/84Products or compounds obtained by lyophilisation, freeze-drying

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Abstract

The invention discloses a kind of anti-acne moisturizing cosmetic face creams and preparation method thereof.The raw material of the cosmetic face cream is made of waltheria indica leaf extract, Gotu Kola P.E, grape seed extract, polymethyl methacrylate, Stearyl Alcohol Stearic Acid ester, fragrant eveningprimrose root oil, olive oil etc..The preparation method of the anti-acne moisturizing cosmetic face cream is specifically to put into polymethyl methacrylate, Stearyl Alcohol Stearic Acid ester etc. in reaction kettle to carry out high-temperature stirring, then it is added as cetostearyl alcohol, triethanolamine etc. through primary mix made of homogeneous, sub-mixtures are obtained after stirring homogeneous, waltheria indica leaf extract isoreactivity ingredient will be added after sub-mixtures again vacuum homogeneous in emulsion pot and obtain ultimate mixture, most obtains finished product cosmetic face cream after cooling, addition auxiliary agent afterwards.The anti-acne moisturizing cosmetic face cream has excellent moisturizing and acne-removal function, there is preferable application prospect in face skin nursing.

Description

A kind of anti-acne moisturizing cosmetic face cream and preparation method thereof
Technical field
The present invention relates to cosmetic technical fields, more particularly to a kind of anti-acne moisturizing cosmetic face cream and preparation method thereof.
Background technique
Acne is also known as whelk, is the chronic inflammation of a kind of hair follicle, sebaceous glands, occurs mainly in the greasiness such as face and thoracic dorsal There are self limiting, skin lesion multiform, such as acne, papule, warts, tubercle in area.It is often accompanied by seborrhea.Controlling for this inflammation at present Treatment has difficulty below: one acne is a kind of lasting multiple and recurrence common inflammatory, wherein allegro city life side Formula, in addition unreasonable diet, sleep insufficiency, work and rest it is abnormal be all cause the disease continue it is multiple and recur one it is main Reason.Exactly this reason significantly limits endo-medicine and reaches the therapeutic modality on treatment mesh ground to adjust endocrine;Its The curative effect of two steroids and antibiotics affirmative, but the side effect abused is very big, should not routinely apply;Thirdly full face is equal Workable product is simultaneously few;The product of various exterior-applied formulations made of its four pure Chinese medicines prescription is processed is simultaneously few, and prevents It is uncertain with the effect for the treatment of whelk, it takes effect unhappy.Determine the state of the mainly epidermis of our skin appearances, epidermis is by angle Matter forms cell and outermost horn cell is constituted, they suffer from oneself powerful updating ability, as long as cell moisture fills Foot, their self-repairing capability is promising.Water is lifespring, and most skin problem is all related with water shortage System, water deficient are easy to cause sebaceous glands excessively to secrete grease, and acne can also make collagenous fibres follow the string and support There is wrinkle in power, and cutis laxa, water deficient can also slow down the metabolic rate of cell, so that excessive pigment can not be just It is often metabolized and deposits, thus moisture is the first element of skin beauty, only carries out moisturizing work, could be laid for facial cosmetic Solid foundation.However, current Pimple removing scream Shortcomings usually in terms of performance of keeping humidity, it can not be using sufficient moisture to Cuo Sore carries out more efficiently dispel.
Summary of the invention
Based on current anti-acne class face cream the problem of not still being able to satisfy consumer demand on performance of keeping humidity, the present invention provides one Kind anti-acne moisturizing cosmetic face cream and preparation method thereof.
A kind of anti-acne moisturizing cosmetic face cream, the raw material of the cosmetic face cream by mass percentage, form as follows:
Waltheria indica leaf extract 1.7~2.9%
Gotu Kola P.E 1.2~2.5%
Grape seed extract 0.6~0.8%
Cetostearyl alcohol 5.5~6.0%
Triethanolamine 1.5~5.5%
Glycerol 6.0~10.0%
Polymethyl methacrylate 4.0~6.0%
Stearyl Alcohol Stearic Acid ester 0.5~7.5%
Vaseline 2.5~3.5%
Fragrant eveningprimrose root oil 1.8~2.2%
Olive oil 0.05~0.15%
Essence 0.01~0.03%
Antioxidant 0.02~0.05%
Preservative 0.1~0.2%
Deionized water surplus.
Above-mentioned anti-acne moisturizing cosmetic face cream contain waltheria indica leaf extract, Gotu Kola P.E, grape seed extract, to night The functional components such as careless oil, olive oil, each functional components are in addition to playing basic effect possessed by itself, also unexpected table Synergistic function is revealed, human endocrine and function can have been adjusted from body metabolism level, fundamentally play moisturizing and dispel The beautification function of acne.The cosmetic face cream has excellent moisturizing anti-acne effect, and the crowd suitable for enduring face acnes puzzlement to the fullest extent uses.
The system of the waltheria indica leaf extract, Gotu Kola P.E and grape seed extract in one of the embodiments, Preparation Method are as follows:
Waltheria indica leaf, centella and grape pip are crushed respectively, are sieved, being added to weight is 30 times, volumetric concentration 70 In~80% ethanol solution, ultrasonic extraction 4~6 hours at 50 DEG C, ultrasonic power 250W then takes supernatant centrifugation, mistake Filter, then by filtrate under conditions of vacuum degree is -0.08MPa rotary evaporation, obtain extract concentrated solution, it is last freeze-dried Obtain waltheria indica leaf extract, Gotu Kola P.E and grape seed extract.
The raw material of the cosmetic face cream by mass percentage, forms as follows in one of the embodiments:
Waltheria indica leaf extract 2.3%
Gotu Kola P.E 1.8%
Grape seed extract 0.7%
Cetostearyl alcohol 5.8%
Triethanolamine 3.5%
Glycerol 8.0%
Polymethyl methacrylate 5.0%
Stearyl Alcohol Stearic Acid ester 4.0%
Vaseline 3.0%
Fragrant eveningprimrose root oil 2.0%
Olive oil 0.1%
Essence 0.02%
Antioxidant 0.03%
Preservative 0.15%
Deionized water surplus.
The essence is any one in ginger extrait, flavoring rose essence, lavender oil in one of the embodiments, Kind.
The antioxidant is selected from butylated hydroxy anisole, allantoin, hydroxypropyl tetrahydro pyrrole in one of the embodiments, Any one muttered in triol.
Any one of the preservative in Nipasol, sorbic acid, triclosan in one of the embodiments,.
The present invention also provides the preparation methods of above-mentioned anti-acne moisturizing cosmetic face cream, comprise the steps of:
(1) by cetostearyl alcohol, triethanolamine, glycerol, deionized water investment homogenizer in, according to 1200~1800 turns/ Rate homogenous disperse 30~40 minutes of minute, obtain primary mix;
(2) it by polymethyl methacrylate, Stearyl Alcohol Stearic Acid ester, vaseline, olive oil investment reaction kettle, improves anti- It answers kettle temperature degree to 88~92 DEG C, is stirred 15~25 minutes under 300~500 revs/min of rate, then to being added in reaction kettle Step (1) resulting primary mix stirs homogeneous 30~50 minutes under 1800~2000 revs/min of rate, obtains secondary Grade mixture;
(3) sub-mixtures that step (2) obtains are transferred in emulsion pot, emulsion pot is vacuumized, keep emulsion pot Internal temperature is 65~75 DEG C, according to rate homogeneous 8~10 minutes of 2000~2200 revs/min, inside subsequent pot to be emulsified When temperature is down to 55 DEG C or less, waltheria indica leaf extract, Gotu Kola P.E, grape seed extract are added into emulsion pot, then According to rate homogeneous 18~20 minutes of 2400~2600 revs/min, ultimate mixture is obtained;
(4) after the ultimate mixture that step (3) obtains is cooled to room temperature, fragrant eveningprimrose root oil, essence, antioxygen are added thereto Agent, preservative are stirred evenly according to 120~160 revs/min of rate, obtain finished product face cream.
The preparation method of above-mentioned anti-acne moisturizing cosmetic face cream, process conditions are mild, controllability is strong, stable product quality, raw Cost economy is produced, large-scale production is suitable for.
Emulsion pot is evacuated to -0.06~-0.1MPa in the step (3) in one of the embodiments,.
The present invention also provides application of the anti-acne moisturizing cosmetic face cream in face skin nursing.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, below in conjunction with specific embodiment, The present invention will be described in further detail.It should be appreciated that the specific embodiments described herein are only used to explain this hair It is bright, it is not intended to limit the present invention.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention The normally understood meaning of technical staff is identical.Term as used herein in the specification of the present invention is intended merely to description tool The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term " and or " used herein includes one or more Any and all combinations of relevant listed item.
Raw materials used and reagent is commercially available common raw material and reagent in following embodiment.
A kind of anti-acne moisturizing cosmetic face cream, the raw material of the cosmetic face cream by mass percentage, form as follows:
Waltheria indica leaf extract 1.7~2.9%
Gotu Kola P.E 1.2~2.5%
Grape seed extract 0.6~0.8%
Cetostearyl alcohol 5.5~6.0%
Triethanolamine 1.5~5.5%
Glycerol 6.0~10.0%
Polymethyl methacrylate 4.0~6.0%
Stearyl Alcohol Stearic Acid ester 0.5~7.5%
Vaseline 2.5~3.5%
Fragrant eveningprimrose root oil 1.8~2.2%
Olive oil 0.05~0.15%
Essence 0.01~0.03%
Antioxidant 0.02~0.05%
Preservative 0.1~0.2%
Deionized water surplus.
Wherein, waltheria indica leaf, acrid flavour;Micro-sweet;Cold nature;Return heart, kidney, lung channel;With expelling wind and removing dampness;Clearing heat and detoxicating function Effect;It is mainly used for treating rheumatism bi Zheng;Abscess of throat;Under humid tropics;Carbuncle swells scrofula, while the skin cares function such as there is beautifying whitening Effect.
Wherein, Gotu Kola P.E mainly contains triterpenoid saponin, because it is promoting skin fibroblasts to secrete collagen egg White effect, more and more attention has been paid to, and started to be applied in cosmetics.Gotu Kola P.E can stimulate deep skin Cell substitutes, and compact epidermis and corium coupling part can make skin limber up, and helps to solve cutis laxa phenomenon, makes skin It is smooth flexible;Promote collagen in skin corium to be formed, regenerates fibrin, reconnect is got up, and skin is made to reach tight Cause smooth effect;Impaired organization healing and consolidation skin can also be helped.
Wherein, grape seed extract is rich in procyanidine, is the effective day of removing people's interior free yl generally acknowledged in the world Right antioxidant.Free radical, absorption that is anti-aging, helping vitamin C and vitamin E can be resisted, uv damage is reduced, subtracts Few melanin deposition, prevents the destruction of collagenous fibres and elastomer, so that skin is kept due elasticity and tension, avoids skin Sagging and wrinkle generates.
Wherein, fragrant eveningprimrose root alias oenothera biennis, line leaf oenothera biennis, cordate telosma, screwtree root, are Myrtales, Oenotheraceae, the moon See that grass category is upright or flare is annual or biennial herb.To contain a large amount of unsaturated fatty acid in clouds grass seeds seed oil (70%).Especially there are a kind of gamma-Linolenic acid (GLA), content 8~9%, for the endemic element to clouds grass seed oil.This γ-Asia Numb acid is easy to be absorbed in human body, and lipid material in adjustable blood, has to reduction cholesterol and atherosclerosis aobvious Write effect.
Wherein, olive oil color is limpid, be in yellow green, have fragranced, rich in Polyphenols antioxidant, vitamin and Unsaturated fatty acid, the squalene contained are easily absorbed by the skin, and enhance skin resistance.Olive oil, which has, to be moistened and maintains Effect essentially consists in and keeps moisture of skin and moisten nutrition skin, so that skin is restored natural elasticity, eliminate and wrinkle is delayed to go out It is existing, slow down skin aging speed.Olive oil can resist ultraviolet light, have the function of mitigation to sunlight sunburn, be not skin of burning Skin.
Above-mentioned anti-acne moisturizing cosmetic face cream contain waltheria indica leaf extract, Gotu Kola P.E, grape seed extract, to night The functional components such as careless oil, olive oil, each functional components are in addition to playing basic effect possessed by itself, also unexpected table Synergistic function is revealed, human endocrine and function can have been adjusted from body metabolism level, fundamentally play moisturizing and dispel The beautification function of acne.The cosmetic face cream has excellent moisturizing anti-acne effect, and the crowd suitable for enduring face acnes puzzlement to the fullest extent uses.
In a preferred embodiment, the waltheria indica leaf extract, Gotu Kola P.E and grape seed extract The preparation method comprises the following steps:
Waltheria indica leaf, centella and grape pip are crushed respectively, are sieved, being added to weight is 30 times, volumetric concentration 70 In~80% ethanol solution, ultrasonic extraction 4~6 hours at 50 DEG C, ultrasonic power 250W then takes supernatant centrifugation, mistake Filter, then by filtrate under conditions of vacuum degree is -0.08MPa rotary evaporation, obtain extract concentrated solution, it is last freeze-dried Obtain waltheria indica leaf extract, Gotu Kola P.E and grape seed extract.
In a preferred embodiment, the raw material of the cosmetic face cream by mass percentage, forms as follows:
Waltheria indica leaf extract 2.3%
Gotu Kola P.E 1.8%
Grape seed extract 0.7%
Cetostearyl alcohol 5.8%
Triethanolamine 3.5%
Glycerol 8.0%
Polymethyl methacrylate 5.0%
Stearyl Alcohol Stearic Acid ester 4.0%
Vaseline 3.0%
Fragrant eveningprimrose root oil 2.0%
Olive oil 0.1%
Essence 0.02%
Antioxidant 0.03%
Preservative 0.15%
Deionized water surplus.
In a preferred embodiment, the essence is any in ginger extrait, flavoring rose essence, lavender oil It is a kind of.
In a preferred embodiment, the antioxidant is selected from butylated hydroxy anisole, allantoin, hydroxypropyl tetrahydro Any one in pyrans triol.
In a preferred embodiment, the preservative is any one in Nipasol, sorbic acid, triclosan Kind.
The present invention also provides the preparation methods of above-mentioned anti-acne moisturizing cosmetic face cream, comprise the steps of:
(1) by cetostearyl alcohol, triethanolamine, glycerol, deionized water investment homogenizer in, according to 1200~1800 turns/ Rate homogenous disperse 30~40 minutes of minute, obtain primary mix;
(2) it by polymethyl methacrylate, Stearyl Alcohol Stearic Acid ester, vaseline, olive oil investment reaction kettle, improves anti- It answers kettle temperature degree to 88~92 DEG C, is stirred 15~25 minutes under 300~500 revs/min of rate, then to being added in reaction kettle Step (1) resulting primary mix stirs homogeneous 30~50 minutes under 1800~2000 revs/min of rate, obtains secondary Grade mixture;
(3) sub-mixtures that step (2) obtains are transferred in emulsion pot, emulsion pot is vacuumized, keep emulsion pot Internal temperature is 65~75 DEG C, according to rate homogeneous 8~10 minutes of 2000~2200 revs/min, inside subsequent pot to be emulsified When temperature is down to 55 DEG C or less, waltheria indica leaf extract, Gotu Kola P.E, grape seed extract are added into emulsion pot, then According to rate homogeneous 18~20 minutes of 2400~2600 revs/min, ultimate mixture is obtained;
(4) after the ultimate mixture that step (3) obtains is cooled to room temperature, fragrant eveningprimrose root oil, essence, antioxygen are added thereto Agent, preservative are stirred evenly according to 120~160 revs/min of rate, obtain finished product face cream.
In a preferred embodiment, emulsion pot is evacuated to -0.06~-0.1MPa in the step (3).
The present invention also provides application of the above-mentioned anti-acne moisturizing cosmetic face cream in face skin nursing.
Below by embodiment, the present invention is furture elucidated.It should be pointed out that the present invention is not intended to be limited to the reality Apply example.
Embodiment 1
The anti-acne moisturizing cosmetic face cream formula of the present embodiment is as follows:
Waltheria indica leaf extract 1.7%
Gotu Kola P.E 1.2%
Grape seed extract 0.6%
Cetostearyl alcohol 5.5%
Triethanolamine 1.5%
Glycerol 6.0%
Polymethyl methacrylate 4.0%
Stearyl Alcohol Stearic Acid ester 0.5%
Vaseline 2.5%
Fragrant eveningprimrose root oil 1.8%
Olive oil 0.05%
Essence 0.01%
Antioxidant 0.02%
Preservative 0.1%
Deionized water surplus.
The anti-acne moisturizing cosmetic face cream of the present embodiment is prepared as follows:
(1) waltheria indica leaf, centella and grape pip are crushed respectively, is sieved, being added to weight is 30 times, volumetric concentration For in 70% ethanol solution, ultrasonic extraction 4 hours at 50 DEG C, ultrasonic power 250W then takes supernatant centrifugation, filtering, Again by filtrate under conditions of vacuum degree is -0.08MPa rotary evaporation, obtain extract concentrated solution, it is last freeze-dried To waltheria indica leaf extract, Gotu Kola P.E and grape seed extract
(2) cetostearyl alcohol, triethanolamine, glycerol, deionized water are put into homogenizer, according to 1200 revs/min Rate homogenous disperse 30 minutes, obtain primary mix;
(3) it by polymethyl methacrylate, Stearyl Alcohol Stearic Acid ester, vaseline, olive oil investment reaction kettle, improves anti- It answers kettle temperature degree to 88 DEG C, is stirred 15 minutes under 300 revs/min of rate, it is resulting then to step (2) are added in reaction kettle Primary mix stirs homogeneous 30 minutes under 1800 revs/min of rate, obtains sub-mixtures;
(4) sub-mixtures that step (3) obtains are transferred in emulsion pot, emulsion pot is vacuumized, keep emulsion pot Internal temperature is 65 DEG C, according to rate homogeneous 8 minutes of 2000 revs/min, subsequent pot internal temperature to be emulsified be down to 55 DEG C with When lower, waltheria indica leaf extract, Gotu Kola P.E, grape seed extract are added into emulsion pot, according still further to 2400 revs/min Rate homogeneous 18 minutes, obtain ultimate mixture;
(5) after the ultimate mixture that step (4) obtains is cooled to room temperature, fragrant eveningprimrose root oil, essence, antioxygen are added thereto Agent, preservative are stirred evenly according to 120 revs/min of rate, are obtained finished product face cream, are denoted as S1.
Embodiment 2
The anti-acne moisturizing cosmetic face cream formula of the present embodiment is as follows:
Waltheria indica leaf extract 2.3%
Gotu Kola P.E 1.8%
Grape seed extract 0.7%
Cetostearyl alcohol 5.8%
Triethanolamine 3.5%
Glycerol 8.0%
Polymethyl methacrylate 5.0%
Stearyl Alcohol Stearic Acid ester 4.0%
Vaseline 3.0%
Fragrant eveningprimrose root oil 2.0%
Olive oil 0.1%
Essence 0.02%
Antioxidant 0.03%
Preservative 0.15%
Deionized water surplus.
The anti-acne moisturizing cosmetic face cream of the present embodiment is prepared as follows:
(1) waltheria indica leaf, centella and grape pip are crushed respectively, is sieved, being added to weight is 30 times, volumetric concentration For in 75% ethanol solution, ultrasonic extraction 5 hours at 50 DEG C, ultrasonic power 250W then takes supernatant centrifugation, filtering, Again by filtrate under conditions of vacuum degree is -0.08MPa rotary evaporation, obtain extract concentrated solution, it is last freeze-dried To waltheria indica leaf extract, Gotu Kola P.E and grape seed extract
(2) cetostearyl alcohol, triethanolamine, glycerol, deionized water are put into homogenizer, according to 1500 revs/min Rate homogenous disperse 35 minutes, obtain primary mix;
(3) it by polymethyl methacrylate, Stearyl Alcohol Stearic Acid ester, vaseline, olive oil investment reaction kettle, improves anti- It answers kettle temperature degree to 90 DEG C, is stirred 20 minutes under 400 revs/min of rate, it is resulting then to step (2) are added in reaction kettle Primary mix stirs homogeneous 40 minutes under 1900 revs/min of rate, obtains sub-mixtures;
(4) sub-mixtures that step (3) obtains are transferred in emulsion pot, emulsion pot is vacuumized, keep emulsion pot Internal temperature is 70 DEG C, according to rate homogeneous 9 minutes of 2100 revs/min, subsequent pot internal temperature to be emulsified be down to 55 DEG C with When lower, waltheria indica leaf extract, Gotu Kola P.E, grape seed extract are added into emulsion pot, according still further to 2500 revs/min Rate homogeneous 19 minutes, obtain ultimate mixture;
(5) after the ultimate mixture that step (4) obtains is cooled to room temperature, fragrant eveningprimrose root oil, essence, antioxygen are added thereto Agent, preservative are stirred evenly according to 140 revs/min of rate, are obtained finished product face cream, are denoted as S2.
Embodiment 3
The anti-acne moisturizing cosmetic face cream formula of the present embodiment is as follows:
Waltheria indica leaf extract 2.9%
Gotu Kola P.E 2.5%
Grape seed extract 0.8%
Cetostearyl alcohol 6.0%
Triethanolamine 5.5%
Glycerol 10.0%
Polymethyl methacrylate 6.0%
Stearyl Alcohol Stearic Acid ester 7.5%
Vaseline 3.5%
Fragrant eveningprimrose root oil 2.2%
Olive oil 0.15%
Essence 0.03%
Antioxidant 0.05%
Preservative 0.2%
Deionized water surplus.
The anti-acne moisturizing cosmetic face cream of the present embodiment is prepared as follows:
(1) waltheria indica leaf, centella and grape pip are crushed respectively, is sieved, being added to weight is 30 times, volumetric concentration For in 80% ethanol solution, ultrasonic extraction 6 hours at 50 DEG C, ultrasonic power 250W then takes supernatant centrifugation, filtering, Again by filtrate under conditions of vacuum degree is -0.08MPa rotary evaporation, obtain extract concentrated solution, it is last freeze-dried To waltheria indica leaf extract, Gotu Kola P.E and grape seed extract
(2) cetostearyl alcohol, triethanolamine, glycerol, deionized water are put into homogenizer, according to 1800 revs/min Rate homogenous disperse 40 minutes, obtain primary mix;
(3) it by polymethyl methacrylate, Stearyl Alcohol Stearic Acid ester, vaseline, olive oil investment reaction kettle, improves anti- It answers kettle temperature degree to 92 DEG C, is stirred 25 minutes under 500 revs/min of rate, it is resulting then to step (2) are added in reaction kettle Primary mix stirs homogeneous 50 minutes under 2000 revs/min of rate, obtains sub-mixtures;
(4) sub-mixtures that step (3) obtains are transferred in emulsion pot, emulsion pot is vacuumized, keep emulsion pot Internal temperature is 75 DEG C, according to rate homogeneous 10 minutes of 2200 revs/min, subsequent pot internal temperature to be emulsified be down to 55 DEG C with When lower, waltheria indica leaf extract, Gotu Kola P.E, grape seed extract are added into emulsion pot, according still further to 2600 revs/min Rate homogeneous 20 minutes, obtain ultimate mixture;
(5) after the ultimate mixture that step (4) obtains is cooled to room temperature, fragrant eveningprimrose root oil, essence, antioxygen are added thereto Agent, preservative are stirred evenly according to 160 revs/min of rate, are obtained finished product face cream, are denoted as S3.
Comparative example 1
Substantially with embodiment 2, difference is the formula and preparation method of the cosmetic face cream of this comparative example, does not add snake mother-in-law Cotyledon extract, final cosmetic face cream obtained are denoted as C1.
Comparative example 2
Substantially with embodiment 2, difference is the formula and preparation method of the cosmetic face cream of this comparative example, does not add accumulated snow Careless extract, final cosmetic face cream obtained are denoted as C2.
Comparative example 3
Substantially with embodiment 2, difference is the formula and preparation method of the cosmetic face cream of this comparative example, does not add grape Seed extract, final cosmetic face cream obtained are denoted as C3.
Comparative example 4
Substantially with embodiment 1, difference is the formula and preparation method of the cosmetic face cream of this comparative example, does not add to night Careless oil, final cosmetic face cream obtained are denoted as C4.
Comparative example 5
Substantially with embodiment 1, difference is the formula and preparation method of the cosmetic face cream of this comparative example, does not add olive Oil, final cosmetic face cream obtained are denoted as C5.
Performance test
Cosmetic face cream prepared by Examples 1 to 3 and comparative example 1~5 is subjected to using effect performance test.
Select the age at 20~30 years old, the facial crowd with acne is randomly divided into 8 groups, every group 15 as test object People, each group skin of face situation, in terms of the difference that there are no significant, 1~8 group respectively in daily early, evening two A period smears cosmetic face cream S1~S3 that the embodiment of the present invention 1~3 is prepared and the beauty that comparative example 1~5 is prepared It is each primary to hold face cream C1~C5, after being used continuously one month, effect assessment is carried out using the method for marking.Full marks be 5 points, 4 ~5 points of expression improvements are splendid;3~4 points of expression improvements are good;2~3 points of expression improvements are general;2 points of following tables Show and be not affected significantly effect, last each group is made even respectively, and the specific situation that scores is as shown in table 1:
Table 1
Test result is as shown above, the cosmetic face cream of embodiment S1~S3 group and the cosmetic face cream of comparative example C1~C5 group It compares, more excellent moisturizing anti-acne effect is all had for user, and the cosmetic face cream of embodiment S2 is with the most excellent Different using effect.It can be seen that from the case where embodiment and comparative example in anti-acne moisturizing cosmetic face cream ingredient of the invention Waltheria indica leaf extract, Gotu Kola P.E, grape seed extract, fragrant eveningprimrose root oil, olive oil produce using effect aobvious Writing influences, and in the case that mentioned component is used in conjunction with, and using effect has very compared to lacking any one ingredient It is obviously improved, it is seen that produce synergistic effect between above-mentioned several ingredients, have a good application prospect.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention Range.

Claims (9)

1. a kind of anti-acne moisturizing cosmetic face cream, which is characterized in that by mass percentage, composition is such as the raw material of the cosmetic face cream Under:
Waltheria indica leaf extract 1.7~2.9%
Gotu Kola P.E 1.2~2.5%
Grape seed extract 0.6~0.8%
Cetostearyl alcohol 5.5~6.0%
Triethanolamine 1.5~5.5%
Glycerol 6.0~10.0%
Polymethyl methacrylate 4.0~6.0%
Stearyl Alcohol Stearic Acid ester 0.5~7.5%
Vaseline 2.5~3.5%
Fragrant eveningprimrose root oil 1.8~2.2%
Olive oil 0.05~0.15%
Essence 0.01~0.03%
Antioxidant 0.02~0.05%
Preservative 0.1~0.2%
Deionized water surplus.
2. anti-acne moisturizing cosmetic face cream according to claim 1, which is characterized in that the waltheria indica leaf extract, accumulated snow Careless extract and grape seed extract the preparation method comprises the following steps:
Waltheria indica leaf, centella and grape pip are crushed respectively, be sieved, be added to weight be 30 times, volumetric concentration be 70~ In 80% ethanol solution, ultrasonic extraction 4~6 hours at 50 DEG C, ultrasonic power 250W then takes supernatant centrifugation, filtering, Again by filtrate under conditions of vacuum degree is -0.08MPa rotary evaporation, obtain extract concentrated solution, it is last freeze-dried To waltheria indica leaf extract, Gotu Kola P.E and grape seed extract.
3. anti-acne moisturizing cosmetic face cream according to claim 1, which is characterized in that the raw material of the cosmetic face cream presses quality Percentage meter forms as follows:
Waltheria indica leaf extract 2.3%
Gotu Kola P.E 1.8%
Grape seed extract 0.7%
Cetostearyl alcohol 5.8%
Triethanolamine 3.5%
Glycerol 8.0%
Polymethyl methacrylate 5.0%
Stearyl Alcohol Stearic Acid ester 4.0%
Vaseline 3.0%
Fragrant eveningprimrose root oil 2.0%
Olive oil 0.1%
Essence 0.02%
Antioxidant 0.03%
Preservative 0.15%
Deionized water surplus.
4. described in any item anti-acne moisturizing cosmetic face creams according to claim 1~3, which is characterized in that the essence is selected from ginger Extrait, flavoring rose essence, any one in lavender oil.
5. described in any item anti-acne moisturizing cosmetic face creams according to claim 1~3, which is characterized in that the antioxidant choosing From any one in butylated hydroxy anisole, allantoin, hydroxypropyl oxinane triol.
6. described in any item anti-acne moisturizing cosmetic face creams according to claim 1~3, which is characterized in that the preservative is selected from Nipasol, sorbic acid, any one in triclosan.
7. a kind of preparation method of anti-acne moisturizing cosmetic face cream as described in any one of claims 1 to 6, which is characterized in that by Following steps composition:
(1) cetostearyl alcohol, triethanolamine, glycerol, deionized water are put into homogenizer, according to 1200~1800 revs/min Rate homogenous disperse 30~40 minutes, obtain primary mix;
(2) by polymethyl methacrylate, Stearyl Alcohol Stearic Acid ester, vaseline, olive oil investment reaction kettle, reaction kettle is improved Temperature stirs 15~25 minutes under 300~500 revs/min of rate to 88~92 DEG C, then to step is added in reaction kettle (1) resulting primary mix stirs homogeneous 30~50 minutes under 1800~2000 revs/min of rate, obtains secondary mixed Close object;
(3) sub-mixtures that step (2) obtains are transferred in emulsion pot, emulsion pot is vacuumized, kept inside emulsion pot Temperature is 65~75 DEG C, according to rate homogeneous 8~10 minutes of 2000~2200 revs/min, subsequent pot internal temperature to be emulsified When being down to 55 DEG C or less, waltheria indica leaf extract, Gotu Kola P.E, grape seed extract are added into emulsion pot, according still further to 2400~2600 revs/min of rate homogeneous 18~20 minutes, obtains ultimate mixture;
(4) after the ultimate mixture that step (3) obtains is cooled to room temperature, fragrant eveningprimrose root oil, essence, anti-oxidant is added thereto Agent, preservative are stirred evenly according to 120~160 revs/min of rate, obtain finished product face cream.
8. the preparation method of anti-acne moisturizing cosmetic face cream according to claim 7, which is characterized in that in the step (3) Emulsion pot is evacuated to -0.06~-0.1MPa.
9. application of described in any item anti-acne moisturizing cosmetic face creams in face skin nursing according to claim 1~6.
CN201910121554.XA 2019-02-16 2019-02-16 A kind of anti-acne moisturizing cosmetic face cream and preparation method thereof Pending CN109620779A (en)

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