CN108670910A - A kind of profit hair composition and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of profits to send out composition and preparation method thereof, by weight, including following component：Moderately removing dandruff ingredient：0.01 ~ 10 part；Surfactant component：1 ~ 10 part；Conditioner ingredient：1 ~ 10 part；Stabilizer element：1 ~ 10 part.By adding certain content and particular kind of moderately removing dandruff ingredient, the profit hair composition being prepared can alleviate itch problem from root, prevent inflammation from generating caused vicious circle to reach, have significant itching-relieving efficacies the present invention；The moderately removing dandruff ingredient has balance scalp fat secretion and inhibits chlosma effect simultaneously, can play anti-dandruff and scalp health effect；And preparation process is simple, it is easy to accomplish, it is suitable for scale volume production.

Description

A kind of profit hair composition and preparation method thereof

Technical field

The present invention relates to daily cosmetics technical field, more particularly to a kind of profit hair composition and preparation method thereof.

Background technology

With the continuous development of society, also along with the continuous evil of environment while people's living standard is become better and better Change, rugged environment pressure influence our every aspect, such as our scalp and hair-care health." head can break, and hair can not Disorderly " possess a health, beautiful hair be always modern people pursuit, therefore we need a mild to be suitable for head The nursing object to hair with opsonic action of skin.

The high hair conditioning product that market is now sold is mostly to have silicon profit hair conditioning object, and silicone oil is high-molecular compound, undecomposable, Not environment friendly type raw material, although silicone oil once brought consumer's body of U.S. really to the next hair conditioning of hair carry and glossiness It tests, but a series of problems that silicone oil is brought is also very important.Also silicone oil forms blocking on human hair scalp, residual is asked Though topic, there is no exact scientific basis, the environmental problem that silicone oil is brought is already very severe.

" with the skin gone, what can the hair adhere to ", scalp such as soil, hair can just be growed like plant, the only good hair of scalp.Shadow Ring scalp health because be known as that product brings into has irritating chemical composition；Barrier function reduction lead to moisture loss so that Dry scalp；Cause scalp inflammation etc. along with chlosma decomposes scalp sebum generation unsaturated fatty acid.The present invention is directed to Above-mentioned factor is produced by improving scalp health after being massaged on scalp and having effects that the profit of deep layer relieving itching and removing dandruff sends out combination Object has been filled up and has now sold the effect of no silicon profit hair improves object single adjusting hair compliance and glossiness in the market.

Invention content

In order to solve the above technical problems, the primary purpose of the present invention is that providing a kind of profit hair composition, the compound energy Enough it is obviously improved the spreadability of product, viscosity that is resistance to ionic and promoting product well.

Profit of the present invention sends out composition, by weight, including following component：

Moderately removing dandruff ingredient：0.01 ~ 10 part；

Surfactant component：1 ~ 10 part；

Conditioner ingredient：1 ~ 10 part；

Stabilizer element：1 ~ 10 part.

Wherein, the moderately removing dandruff ingredient, by weight, including following component：

0.01 ~ 1 part of piroctone olamine salt；

0.05 ~ 4 part of foreign jujube tree bark extract；

0.01 ~ 1 part of peony root extractive.

Preferably, the moderately removing dandruff ingredient, by weight, including following component：

0.1 ~ 0.5 part of piroctone olamine salt；

0.1 ~ 2 part of foreign jujube tree bark extract；

0.1 ~ 0.5 part of peony root extractive.

Wherein, the surfactant component is selected from cationic surfactant, nonionic surfactant One or two compounding；Wherein, the cationic surfactant is selected from cetyl trimethyl ammonium chloride, hard ester-trimethyl chlorine Change one or both of ammonium, behenyl base trimethyl ammonium chloride；The nonionic surfactant is selected from stearine, sugarcane One or more of sugared stearate.

Wherein, the conditioner ingredient is selected from stearamidopropyl dimethylamine, cetanol ethylhexoate, octyl 12 Alcohol, pentaerythrite four（Thylhexoic acid）One or more of ester.

Wherein, the stabilizer element is selected from cetanol, cetostearyl alcohol, one kind in PEG-150 distearates or It is several.

Profit hair composition of the present invention further includes by weight 0.1 ~ 5 part of moisturizer, scalp conditioner 0.05 ~ 5 part, 0.1 ~ 2 part of essence and 50-90 parts of water.

Wherein, the moisturizer is selected from one kind of lactic acid, glycerine, 1,3-PD, butanediol, different malt, maltodextrin Or it is several；The scalp conditioner is selected from purslane（PORTULACA OLERACEA）Extract, strigose oat （AVENA STRIGOSA）Seed extract, grape（VITIS VINIFERA）Seed extract, tocopherol（Vitamin E）, pea （PISUM SATIVUM）Extract, Japanese Swertia patens（SWERTIA JAPONICA）Extract, Chinese herbaceous peony（PAEONIA OFFICINALIS）Root extract, Cortex Magnoliae Officinalis（MAGNOLIA OFFICINALIS）Bark extract, arbor-vitae（BIOTA ORIENTALIS）Leaf extract, Chinese honey locust（GLEDITSIA SINENSIS）Extract, Melaleuca alternifolia（MELALEUCA ALTERNIFOLIA）One or more of leaf oil, bean cotyledon cauliflower/leaf/stem extraction, Urtica dioica seed leaf extract.

Wherein, it is described profit hair composition pH value be 3.5-4.5,4# rotors with the viscosity of 63rpm rotating speeds be 7500 ~ 14000。

The invention also discloses the preparation methods that above-mentioned profit sends out composition, include the following steps：

（1）It is added water in water phase pot according to proportioning, sequentially adds pH regulators, stirring heating is heated to 80 ~ 85 DEG C, obtains Water phase material；

（2）Surfactant component, conditioner ingredient and stabilizer element are sequentially added into emulsification pot according to proportioning, stirring rises Temperature is heated to 75 ~ 80 DEG C, obtains transparent no particle oil phase material；

（3）By step（1）Obtained water phase material is pumped into emulsification pot, is stirred and is pumped into step under processing condition（2）Obtained oil phase Material, homogeneous stir 1 ~ 10min, keep the temperature 1 ~ 10min, and moisturizer, moderately removing dandruff ingredient, scalp tune finally is added according to proportioning Reason agent essence stirs evenly.

Compared with prior art, the present invention having the advantages that：

1）The present invention is by adding certain content and particular kind of moderately removing dandruff ingredient, the profit hair composition being prepared, energy It is enough to alleviate itch problem from root, it prevents inflammation from generating caused vicious circle to reach, there are significant itching-relieving efficacies；Together When the moderately removing dandruff ingredient there is balance scalp fat secretion and inhibit chlosma effect, can play anti-dandruff with scalp health Effect.

2）The present invention by add the moderately removing dandruff ingredient of certain content, surfactant component, conditioner ingredient and Stabilizer element etc. is prepared accessible scalp and can balance scalp after scalp massage by the coordinated of each component Fat secretion, the effect of promoting scalp barrier ability, while having to the good hair conditioning of hair, improve glossiness and smoothness Scalp care profit hair composition product.

3）Preparation process of the present invention is simple, it is easy to accomplish, it is suitable for scale volume production.

Description of the drawings

Fig. 1 is subregion schematic diagram in head of the present invention.

Specific implementation mode

It is further illustrated the present invention below by specific implementation mode, following embodiment is the preferable embodiment party of the present invention Formula, but embodiments of the present invention are not limited by following embodiments.

The raw material that the embodiment of the present invention and comparative example use is as follows, but is not limited only to these raw materials：

Moderately removing dandruff ingredient：

Piroctone olamine salt：Mass concentration is 100%, purchased in market；

Foreign jujube tree bark extract：Mass concentration is 5%, purchased in market；

Peony root extractive：Mass concentration is 100%, purchased in market；

Surfactant component：

Cetyl trimethyl ammonium chloride：Mass concentration is 80%, purchased in market；

Hard ester-trimethyl ammonium chloride：Mass concentration is 80%, purchased in market；

Behenyl base trimethyl ammonium chloride：Mass concentration is 80%, purchased in market；

Stearine：Mass concentration is 100%, purchased in market；

Glycerol monolaurate：Mass concentration is 100%, purchased in market；

Sucrose stearate：Mass concentration is 100%, purchased in market；

Conditioner ingredient：

Stearamidopropyl dimethylamine：Mass concentration is 100%, purchased in market；

Cetanol ethylhexoate：Mass concentration is 100%, purchased in market；

Octyl dodecanol：Mass concentration is 100%, purchased in market；

Pentaerythrite four（Thylhexoic acid）Ester：Mass concentration is 100%, purchased in market；

Stabilizer element：

Cetanol：Mass concentration is 100%, purchased in market；

Cetostearyl alcohol：Mass concentration is 100%, purchased in market；

PEG-150 distearates：Mass concentration is 100%, purchased in market；

Other raw materials also it is purchased in market to obtain the final product.

The stability test method of profit hair composition：Composition is sent out to the profit of embodiment 1-5 and comparative example 1-6, is placed in 50 DEG C storage 1 month, 25 DEG C of room temperature store 1 month, -15 DEG C of low temperature store 1 month, daylight store one month, restore to room temperature Appearance is observed, test result is as shown in table 5.

The viscosity determining procedure of profit hair composition：The profit of embodiment 1-5 and comparative example 1-6 are sent out into composition, are placed in room temperature 25 DEG C 24 hours, carry out viscosity test, use instrument：NDJ-1 type viscosimeters；Test condition：Using No. 4 rotors, in 30rpm Rotating speed, by viscosimeter using regulation start 0.5 minute after read stable viscosity data, test result is as shown in table 5.

The test method of the anti-dandruff effect of profit hair composition：

One, dandruff assessment method：

The artificial point system of dandruff menace level：Entire scalp is averagely divided into 12 regions（Each 6 regions in left and right）, to each Region is scored, and is the sum of 6 region score values per half a head total score, is tracked and recorded the situation of change of score value.

Head subregion is as shown in Figure 1；

Specific method is as shown in table 1 with reference to clinical medicine adherence ten grades of point systems of dandruff：

Table 1

Two, test equipment：

Dermoscopy（Dermal DOC-HR, Derma Medical）

Dermoscopy is a set of integration system for digitizing illumination microscope and digitizing dermal imaging, passes through integration LED light can make camera be directly adjacent to skin to obtain the diagnostic image of short distance.

Three, subject's screening conditions：

1, inclusion criteria

1) age：18-65 Sui, male or female；

2) manually scoring is more than X points/half a head to dandruff menace level（This tests X=5, requires to determine to subject by applicant, Specific standards of grading are see ten grades of scorings of dandruff）；

3) present or nearest three months recipient sites do not participate in other anti-dandruff related efficacy clinical test persons；

4) strictly using product and follow-up can be completed in accordance with the requirement of research approach.

2, exclusion criteria

1) test position uses other anti-dandruff product persons during testing；

2) test product person can not be used according to the rules；

3) there are the scalp skins patients such as eczema, psoriasis, favus of the scalp, asbestos sample pityriasis, and the observation of other influences scalp in head The case where；

4) it uses within nearly one week antihistamine or used immunosuppressor in nearly one month；

5) nearly two months recipient sites use any anti-inflammatory drug；

6) insulin-dependent diabetic；

7) use may personal care articles influential on test result in half a year；

8) nursing period or pregnancy women；

9) crowds such as allergic constitution, allergic dermatitis have skin disease or history of disease；

10) receive the crowd of dermatological treatment or take carboxylic acid class, whitening class and anti-aging class medicine in one month Object

Four, sample frequency of use, dosage and method：

After the complete cleaning shampoo of normal use, embodiment 1-5 and comparative example 1-6 and blank control group are subjected to half a head examination respectively With as shown in table 2.

Table 2

Subject is scored by professional effect panelists using preceding on probation after two weeks：

Dandruff improvement rate n=(W2-WO)/WO*100%

Wherein, W2 is the scoring using sample scalp dandruff after two weeks；

WO is the scoring that sample front leather point bits are not used；

Five, test result is as shown in table 5.

The test method of the antipruritic effect of profit hair composition：

One, antipruritic grade scoring standard is as shown in table 3：

Table 3

Two, subject's screening conditions：

1, inclusion criteria

1) age：18-65 Sui, male or female；

2) present or nearest three months recipient sites do not participate in other anti-dandruff and itching-relievings related efficacy clinical test person；

3) strictly using product and follow-up can be completed in accordance with the requirement of research approach.

2, exclusion criteria

1) test position uses other anti-dandruff and itching-relievings product person during testing；

2) test product person can not be used according to the rules；

3) there are the scalp skins patients such as eczema, psoriasis, favus of the scalp, asbestos sample pityriasis, and the observation of other influences scalp in head The case where；

4) it uses within nearly one week antihistamine or used immunosuppressor in nearly one month；

5) nearly two months recipient sites use any anti-inflammatory drug；

6) insulin-dependent diabetic；

7) use may personal care articles influential on test result in half a year；

8) nursing period or pregnancy women；

9) crowds such as allergic constitution, allergic dermatitis have skin disease or history of disease；

10) receive the crowd of dermatological treatment or take carboxylic acid class, whitening class and anti-aging class medicine in one month Object

Three, sample frequency of use, dosage and method：

After the complete cleaning shampoo of normal use, embodiment 1-5 and comparative example 1-6 and blank control group are subjected to half a head examination respectively With as shown in table 4.

Table 4

Subject uses preceding and on probation scored for product itch degree with feeling after a week：

Itch improvement rate n=(W1-WO)/WO*100%

Wherein, W1 is the scoring using sample itching of the scalp situation after a week；

WO is the scoring of itching of the scalp situation before sample is not used；

Four, test result is as shown in table 5.

Embodiment 1-5 and comparative example 1-6：

It is formulated by shown in table 5,（1）It is added water in water phase pot according to proportioning, sequentially adds pH regulators, stirring heating, heating To 80 ~ 85 DEG C, water phase material is obtained；（2）According to proportioning by surfactant component, conditioner ingredient and stabilizer element add successively Enter and emulsify pot, stirring heating is heated to 75 ~ 80 DEG C, obtains transparent no particle oil phase material；（3）By step（1）Obtained water phase material It is pumped into emulsification pot, stirs and be pumped into step under processing condition（2）Obtained oil phase material, homogeneous 1 ~ 10min of stirring, heat preservation 1 ~ 10min is finally added moisturizer, moderately removing dandruff ingredient, scalp conditioner essence according to proportioning and stirs evenly up to profit hair Composition, the results are shown in Table 5 for test performance.

The each component weight percent of 5 embodiment and comparative example of table when each the performance test results

The present invention is by adding certain content and particular kind of moderately removing dandruff it can be seen from the embodiment and comparative example of table 5 Ingredient, the profit hair composition being prepared, can alleviate itch problem from root, prevent inflammation from generating caused dislike to reach Property cycle, have significant itching-relieving efficacies；The moderately removing dandruff ingredient has balance scalp fat secretion and inhibits horse traction color simultaneously Bacterium acts on, and can play anti-dandruff and scalp health effect.

In addition, the profit hair composition to embodiment 1-5 and comparative example 1-6 carries out enclosed type patch test：

One, the selection of subject

1）Select the 18-60 Sui volunteer for meeting requirement of experiment as study subject.

2）The person that cannot select following situations is as subject

2.1）Use antihistamine or immunosuppressor person in one month within nearly one week；

2.2）Recipient site applies any anti-inflammatory drug person in nearly two months；

2.3）Subject is not cured with inflammatory dermatoses clinic；

2.4）Insulin-dependent diabetes mellitus patient；

2.5）Receiving the asthma or other chronic respiratory disease patients for the treatment of；

2.6）The person that receives anticancer chemotherapy in nearly 6 months；

2.7）Immune deficiency or autoimmune disease patient；

2.8）Nursing period or gravid woman；

2.9）Bilateral mastectomy and bilateral axillary lymph node dissection person；

2.10）At skin position to be tried test result is influenced due to scar, pigment, atrophy, nevus flammeus or other flaws Judgement person；

2.11）Participate in other clinical trial investigators；

2.12）The highly sensitive person of constitution；

2.13）Non- aspiration participant cannot empirically require to complete specified content person；

Two, method

1）Skin closure type patch is tested

1.1）By subject enrollment standard select participate in experiment personnel, at least 30.

1.2）Area is selected to be no more than 50mm², depth about 1mm qualified spot try equipment.It is small that tested material is put into spot examination device Interior, dosage are about 0.020g-0.025g（Solid or semisolid）Or 0.020mL-0.025mL（Liquid）.Tested material is makeup When the product product original, control wells are blank control（Any substance is not set）, when tested material is the cosmetics after dilution, in control wells Use the diluent of the cosmetics.Back or the forearm of subject will be pasted on low sensitization adhesive tape added with the spot of tested material examination device Bent side is gently pressed with palm and is allowed to equably be pasted on skin, continued for 24 hours.

1.3）The 30min after removal tested material spot examination device（After impression disappearance）, for 24 hours with 48h press 2 standard sight of table Dermoreaction, and record observation result.

6 skin closure type patch test dermoreaction grade scale of table

Result judgement：The number for occurring 1 grade of skin adverse reaction in 30 subjects is more than 5 or 2 grades of skin adverse reactions Number be more than 2（The number of 2 order reaction of deodorising product patch test is more than 5）, or occur any 13 grades or 3 grades or more When skin adverse reaction, judgement tested material has skin adverse reaction to human body.

Three, test result

Meet subject's condition be selected in number 33, wherein have 33 it is negative（0 grade of grading system）, according to above-mentioned judgement Standard can determine that human body, without skin adverse reaction, mildness is preferable.

Claims (10)

1. a kind of profit sends out composition, which is characterized in that by weight, including following component：

Moderately removing dandruff ingredient：0.01 ~ 10 part；

Surfactant component：1 ~ 10 part；

Conditioner ingredient：1 ~ 10 part；

Stabilizer element：1 ~ 10 part.

2. profit according to claim 1 sends out composition, which is characterized in that the moderately removing dandruff ingredient, by weight, packet Include following component：

0.01 ~ 1 part of piroctone olamine salt；

0.05 ~ 4 part of foreign jujube tree bark extract；

0.01 ~ 1 part of peony root extractive.

3. profit according to claim 2 sends out composition, which is characterized in that the moderately removing dandruff ingredient, by weight, packet Include following component：

0.1 ~ 0.5 part of piroctone olamine salt；

0.1 ~ 2 part of foreign jujube tree bark extract；

0.1 ~ 0.5 part of peony root extractive.

4. profit according to claim 1 sends out composition, which is characterized in that the surfactant component be selected from selected from sun from One or both of sub- surfactant, nonionic surfactant compound；Wherein, the cationic surfactant is selected from One or both of cetyl trimethyl ammonium chloride, hard ester-trimethyl ammonium chloride, behenyl base trimethyl ammonium chloride；It is described non- Ionic surface active agent is selected from one or more of stearine, sucrose stearate.

5. profit according to claim 1 sends out composition, which is characterized in that the conditioner ingredient is selected from stearamide propyl Dimethylamine, cetanol ethylhexoate, octyl dodecanol, pentaerythrite four（Thylhexoic acid）One or more of ester.

6. profit according to claim 1 or 2 sends out composition, which is characterized in that the stabilizer element is selected from cetanol, whale Wax stearyl alcohol, one or more of PEG-150 distearates.

7. profit according to claim 1 sends out composition, which is characterized in that further include moisturizer 0.1 ~ 5 by weight Part, 0.05 ~ 5 part of scalp conditioner, 0.1 ~ 2 part of essence and 50-90 parts of water.

8. profit according to claim 7 sends out composition, which is characterized in that the moisturizer is selected from lactic acid, glycerine, 1,3- third The one or more of glycol, butanediol, different malt, maltodextrin；The scalp conditioner is selected from purslane （PORTULACA OLERACEA）Extract, strigose oat（AVENA STRIGOSA）Seed extract, grape（VITIS VINIFERA）Seed extract, tocopherol（Vitamin E）, pea（PISUM SATIVUM）Extract, Japanese Swertia patens （SWERTIA JAPONICA）Extract, Chinese herbaceous peony（PAEONIA OFFICINALIS）Root extract, Cortex Magnoliae Officinalis（MAGNOLIA OFFICINALIS）Bark extract, arbor-vitae（BIOTA ORIENTALIS）Leaf extract, Chinese honey locust（GLEDITSIA SINENSIS）Extract, Melaleuca alternifolia（MELALEUCA ALTERNIFOLIA）Leaf oil, bean cotyledon cauliflower/leaf/stem extraction One or more of object, Urtica dioica seed leaf extract.

9. according to claim 1-8 any one of them moisten hair composition, which is characterized in that it is described profit hair composition pH value be 3.5-4.5,4# rotor are with the viscosity of 63rpm rotating speeds for 7500 ~ 14000.

10. such as the preparation method of claim 1-9 any one of them profit hair composition, which is characterized in that include the following steps：

（1）It is added water in water phase pot according to proportioning, sequentially adds pH regulators, stirring heating is heated to 80 ~ 85 DEG C, obtains Water phase material；

（2）Surfactant component, conditioner ingredient and stabilizer element are sequentially added into emulsification pot according to proportioning, stirring rises Temperature is heated to 75 ~ 80 DEG C, obtains transparent no particle oil phase material；

（3）By step（1）Obtained water phase material is pumped into emulsification pot, is stirred and is pumped into step under processing condition（2）Obtained oil phase Material, homogeneous stir 1 ~ 10min, keep the temperature 1 ~ 10min, and moisturizer, moderately removing dandruff ingredient, scalp tune finally is added according to proportioning Reason agent essence stirs evenly.