CN108670886A - A kind of externally used coating agent improving the colour of skin - Google Patents
A kind of externally used coating agent improving the colour of skin Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention discloses a kind of externally used coating agent improving the colour of skin, include active constituent for improve the colour of skin of the mass fraction 25% to 35%；The active constituent includes according to mass fraction：25 parts to 35 parts of whitening active ingredients, 10 parts to 15 parts of cutin metabolic activity ingredient and 5 parts to 10 parts of skin resistance improve active constituent；The skin resistance improves in active constituent, includes according to mass fraction：75 parts to 85 parts of plant polyose, 5 parts to 10 parts of epidermal growth factor and 10 parts to 15 parts of angelica extract.The present invention is added to effectively U.S. active constituent and cutin metabolic activity ingredient under the premise of ensureing drug safety, and to combine whitening effect and exfoliation, skin-whitening effect is relatively used alone whitening composition and is significantly improved.
Description
Technical field
The invention belongs to filed of daily-use chemical industry, more particularly, to a kind of externally used coating agent improving the colour of skin.
Background technology
Asian aesthetic standard, it is believed that whitening skin, it is bright, ruddy be healthy and beautiful embodiment, but most of Asia
People's colour of skin is partially yellow, shade, there are problems that pigment deposition since the physiology such as gene, ultraviolet light, aging and environment influence.Therefore
The technical market for improving the colour of skin is huge.At present improve the colour of skin means include use coating agent, such as the emulsion containing whitening composition,
Creme, the emulsion that ingredient is blocked containing ultraviolet light, spraying, the cleanser of the Metabolite containing cutin, facial mask etc.；Also include using doctor
It treats beauty means and reinforces the means such as skin metabolism or blocking and pigment, such as the shining skin of tartaric acid, the shining skin of crystallite and the shining skin of laser.
However, there are larger security risks for above-mentioned medical procedure, while skin convalescence is longer, or even influences skin and be good for
Health is not suitable for being widely used for a long time.And common coating agent is since effective ingredient concentration and single effect often have little effect.It is general
The general whitening de-etiolation ingredient of logical coating agent is tyrosinase inhibitor such as hydroquinone, Arbutin etc., however these ingredients are transdermal
Absorptivity is relatively low, irritation is stronger, generally cannot simultaneously be used with skin keratin Metabolite.However pigment deposition problem and angle
Matter layer problem often exists simultaneously, and causes skin color dim, if cannot solve the problems, such as that pigment deposition and cuticula are asked simultaneously
Topic, often due to environment influences and skin growth and aging influence, coating agent is bad or be difficult to hold for colour of skin improvement
Long.Especially when cuticula problem is serious, the Transdermal absorption of common whitening composition is further influenced so that colour of skin improvement
It has a greatly reduced quality.
Invention content
For the disadvantages described above or Improvement requirement of the prior art, the present invention provides a kind of externally used coatings improving the colour of skin
Agent, its object is to by improving skin resistance and metabolic rate, reinforcing skin keratin metabolism reduces cutaneous sensibility, to comprehensive
It closes whitening active and cutin metabolism, improve the colour of skin, thus solution must not be carried out at the same time and solve the problems, such as pigment deposition and cutin
The technical problem that layer problem causes colour of skin improvement undesirable.
To achieve the above object, according to one aspect of the present invention, a kind of externally used coating agent improving the colour of skin is provided,
Include active constituent for improve the colour of skin of the mass fraction 25% to 35%；The active constituent is according to mass fraction packet
It includes：25 parts to 35 parts of whitening active ingredients, 10 parts to 15 parts of cutin metabolic activity ingredient and 5 parts to 10 parts of skin
Resistance improves active constituent；
The skin resistance improves in active constituent, includes according to mass fraction：75 parts to 85 parts of plant polyose, 5 parts
To 10 parts of epidermal growth factor and 10 parts to 15 parts of angelica extract.
Preferably, the externally used coating agent for improving the colour of skin, the plant polyose is astragalus polyose, tremella polysaccharides, brown
The one or more composition of algae carbohydrate gum.
Preferably, it is described improve the colour of skin externally used coating agent, the plant polyose be astragalus polyose or fucoidin, it is excellent
Astragalus polyose and fucoidin are selected as according to mass ratio 1:2 mixture.
Preferably, the externally used coating agent for improving the colour of skin, the angelica extract are that Ligustilide mass fraction is big
In the Radix Angelicae Sinensis water extract equal to 1.2%.
Preferably, the externally used coating agent for improving the colour of skin, in the whitening active ingredients, including 10 parts of mass fraction
It is to 20 parts of the roots of Dahurain angelica, 10 parts to 20 parts of PORIA ALBA, 10 parts to 20 parts of the bletilla striata, 10 parts to 20 parts of Rhizoma Atractylodis Macrocephalae, mass fraction
1% to 3% tyrosine kinase inhibitor and the vitamin C of mass fraction 1% to 3% or derivatives thereof.
Preferably, the externally used coating agent for improving the colour of skin, the whitening active ingredients are the white of 10 parts of mass fraction
The root of Dahurian angelica, 10 parts of PORIA ALBA, 10 parts of the bletilla striata, 10 parts of Rhizoma Atractylodis Macrocephalae, the tyrosine kinase inhibitor that mass fraction is 3%, Yi Jizhi
Measure the Ascorbyl Tetraisopalmitate of score 3%.
Preferably, the externally used coating agent for improving the colour of skin, the cutin metabolic activity ingredient includes tartaric acid, salicylic acid
One or more mixing.
Preferably, the externally used coating agent for improving the colour of skin, the cutin metabolic activity ingredient are tartaric acid.
Preferably, it is described improve the colour of skin externally used coating agent comprising matrix, the matrix contain light-coloured vinegar, mature vinegar and/or
Lactic acid, the matrix pH value is between 3 to 5.
In general, through the invention it is contemplated above technical scheme is compared with the prior art, due to anti-using skin
Property the active constituent that improves, including plant polyose, epidermal growth factor and angelica extract improve skin resistance and metabolism speed
Rate is added to effectively U.S. active constituent and cutin metabolic activity ingredient, to combine U.S. under the premise of ensureing drug safety
White effect and exfoliation, skin-whitening effect are relatively used alone whitening composition and are significantly improved.
Optimal technical scheme, plant polyose is using astragalus polyose and fucoidin according to mass ratio 1:2 mixture, for
Raising skin resistance, the effect for reducing sensibility are apparent.
Description of the drawings
Fig. 1 be the embodiment of the present invention 1 user use front and back comparison diagram, wherein Figure 1A be under white light use front and back skin
Photo, Figure 1B are to use front and back eye detail view, and Fig. 1 C are using front and back facial detail view, and Fig. 1 D are under ultraviolet light using front and back
Skin photo；
Fig. 2 is that the user of the embodiment of the present invention 2 uses front and back facial Detail contrast figure；
Fig. 3 is the user of the embodiment of the present invention 3 using using front and back skin photo under white light.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.As long as in addition, technical characteristic involved in the various embodiments of the present invention described below
It does not constitute a conflict with each other and can be combined with each other.
The externally used coating agent provided by the invention for improving the colour of skin can be the forms such as emulsion, creme or facial mask, and it includes matter
Active constituent and matrix for improve the colour of skin of the amount score 25% to 35%.
The active constituent includes according to mass fraction：25 parts to 35 parts of whitening active ingredients, 10 parts to 15 parts cutin
Metabolic activity ingredient and 5 parts to 10 parts of skin resistance improve active constituent；
The whitening active ingredients：Including 10 parts to 20 parts of the root of Dahurain angelica of mass fraction, 10 parts to 20 parts of PORIA ALBA, 10 parts
To 20 parts of the bletilla striatas, 10 parts to 20 parts of Rhizoma Atractylodis Macrocephalae, the tyrosine kinase inhibitor that mass fraction is 1% to 3% and quality
Vitamin C of score 1% to 3% or derivatives thereof.Preferably：The root of Dahurain angelica that the whitening active ingredients are 10 parts, 10 parts white
Poria cocos, 10 parts of the bletilla striata, 10 parts of Rhizoma Atractylodis Macrocephalae, the tyrosine kinase inhibitor that mass fraction is 3% and mass fraction 3%
Vitamin C or derivatives thereof.Common Chinese medicine whitening composition, i.e. " 12 is white ", commercialized important whitening formula is typically chosen
Wherein seven kinds compoundings；Chinese medicine whitening composition of the present invention and the chemical composition compounding for specifying whitening function, therefore select upper Chinese medicine
Ingredient is simple and effective as possible, while safety and stability, thus select wherein whitening dispel yellow ingredient with obvious effects, effect persistently, make
It is that formula is added in Chinese medicine whitening composition with mild, the preferable root of Dahurain angelica of the synergistic effect that cooperates, PORIA ALBA, the bletilla striata, Rhizoma Atractylodis Macrocephalae, preferably
Using its Ultramicro-powder, i.e., grain size is at 48 μm~25 μm, and specification is in 300 mesh to 500 mesh powders；Another aspect vitamin C and its
Derivative is the current degradation preferably most preferred raw material of melanin.PORIA ALBA, the bletilla striata, Rhizoma Atractylodis Macrocephalae are that whitening yellow effect of dispelling is bright in Chinese medicine
Aobvious ingredient, have more lasting whitening effect, however the present invention due to exfoliating ingredient combination use, Chinese medicine whitening
The access times of ingredient can substantially reduce, in order under the premise of less access times and coating time, ensure whitening effect,
Vitamin C or derivatives thereof is added to ensure the function and effect of whitening composition in the short time, preferably four different palmitic acid of ascorbic acid
Ester, chemical property are stablized, and are suitble to compound with traditional Chinese medicine ingredients, fat-soluble good.
The cutin metabolic activity ingredient includes azelaic acid, salicylic acid, and/or mature vinegar.It is preferred that the cutin metabolic activity
Ingredient is azelaic acid, salicylic acid and mature vinegar according to mass ratio 2:7:1 mixture.Azelaic acid, tartaric acid, salicylic acid can be very
Good promotion keratoderma metabolism, traditional mature vinegar is the good solvent of the traditional Chinese medicine ingredients such as PORIA ALBA, the bletilla striata, Rhizoma Atractylodis Macrocephalae, can
Promote skin to absorb nutritive effect ingredient, while keratoderma can be promoted to be metabolized.
The skin resistance improves active constituent：75 parts to 85 parts of plant polyose, 5 parts to 10
The epidermal growth factor and 10 parts to 15 parts of angelica extract of part.The plant polyose be astragalus polyose, tremella polysaccharides,
The one or more composition of fucoidin；The plant polyose is preferably astragalus polyose or fucoidin, more preferably Radix Astragali
Polysaccharide and fucoidin are according to mass ratio 1:2 mixture.The epidermal growth factor is EGF freeze-dried powders.The Radix Angelicae Sinensis extraction
Object is the Radix Angelicae Sinensis water extract that Ligustilide mass fraction is more than or equal to 1.2%.The present invention has been especially added with skin resistance and has improved work
Property ingredient, include with reduce sensibility plant polyose, stimulate promoting epidermization epidermal growth factor, in the combination of both
Under, high irritating whitening composition and cutin Metabolite could use, ensure the tolerance journey of cutin metabolism and skin simultaneously
Degree is in tolerance interval so that whitening composition and cutin metabolic energy are completed at the same time, and such skin is while cutin is metabolized, tool
There is preferable absorbability, has larger help for the absorption of whitening active ingredients and de-etiolation active constituent.In plant polyose, Radix Astragali
Polysaccharide can imitate raising immunocompetence, fucoidin can effectively moisturizing antiallergic, repair skin barrier effect, consolidate whitening and dispel Huang
Effect, the two is according to mass ratio 1:2 compoundings improve the apparent reinforcement of the more single addition of effect of skin resistance.The present invention adds simultaneously
Add angelica extract, enables the facial micro- blood circulation of capillary reinforce, while reinforcing the absorbability of local skin, provide foot
Enough nutriments are metabolized for epithelial cell, to ensure the absorption of each active ingredient and play a role, reduce adverse reaction,
Also improve the colour of skin, it appears the ruddy effect of skin.
The matrix contains light-coloured vinegar, mature vinegar and/or lactic acid, and the matrix pH value is between 3 to 5.It is wherein used to provide steady
Fixed acidic environment simultaneously plays the herbal medicine efficacy in the active ingredient.
The externally used coating agent provided by the invention for improving the colour of skin is prepared according to the following steps：
(1) according to formula rate dispensing；
(2) soluble ingredient in dispensing is added to mixing in matrix successively and dissolved；
(3) by the non-solubility material pulverizing in formula, 300 mesh to 500 mesh is crossed and are sieved, be added in matrix simultaneously mixing.
It is embodiment below：
Embodiment 1
A kind of externally used coating agent improving the colour of skin is facial mask, it includes mass fraction 30% for improving the colour of skin
Active constituent and matrix.
The active constituent includes according to mass fraction：30 parts of whitening active ingredients, 12 parts of cutin metabolic activity ingredients,
And 8 parts of skin resistance improves active constituent；
The whitening active ingredients are：The root of Dahurain angelica Ultramicro-powder of 10 parts of mass fraction, 10 parts of PORIA ALBA Ultramicro-powder, 10 parts
The bad blood of bletilla striata Ultramicro-powder, 10 parts of Rhizoma Atractylodis Macrocephalae Ultramicro-powder Ultramicro-powder, the ursin that mass fraction is 3% and mass fraction 3%
Sour four different palmitates.
The cutin metabolic activity ingredient includes mature vinegar.
The skin resistance improves active constituent：80 parts of plant polyose, the life of 8 parts of epidermis
The long factor and 12 parts of angelica extract.The plant polyose is astragalus polyose and fucoidin according to mass ratio 1:2 it is mixed
Close object.The epidermal growth factor is EGF freeze-dried powders.The angelica extract is Radix Angelicae Sinensis water extract, Ligustilide quality point
Number is 1.5%.
The matrix pH value is 4.
The externally used coating agent provided in this embodiment for improving the colour of skin is prepared according to the following steps：
(1) according to formula rate dispensing；
(2) soluble ingredient in dispensing is added to mixing in matrix successively and dissolved；
(3) by the non-solubility material pulverizing in formula, 500 mesh sieve is crossed, is added in matrix simultaneously mixing.
By the external application coating agent provided in this embodiment for improving the colour of skin, face 1h is coated, 5 times a week, using goddess in the moon's skin
It decodes robot (being purchased from the anti-ageing limited liability company of robot of goddess in the moon's medicine) and records skin condition before and after using 4 weeks,
Shown in as shown in Fig. 1 and table 1, skin-whitening degree, which has, to be significantly improved, and has no allergic phenomena.
Table 1
| Use preceding solution code value | Using solving code value after 4 weeks | |
| Whitening degree | 178.829 | 199.643 |
| Color spot | 7.173% | 5.057% |
Embodiment 2
A kind of externally used coating agent improving the colour of skin is facial mask, it includes mass fraction 35% for improving the colour of skin
Active constituent and matrix.
The active constituent includes according to mass fraction：35 parts of whitening active ingredients, 10 parts of cutin metabolic activity ingredients,
5 and part skin resistance improve active constituent；
The whitening active ingredients are：The root of Dahurain angelica Ultramicro-powder of 15 parts of mass fraction, 15 parts of PORIA ALBA Ultramicro-powder, 15 parts
The bad blood of bletilla striata Ultramicro-powder, 15 parts of Rhizoma Atractylodis Macrocephalae Ultramicro-powder Ultramicro-powder, the ursin that mass fraction is 2% and mass fraction 2%
Sour four different palmitates.
The cutin metabolic activity ingredient includes azelaic acid.
The skin resistance improves active constituent：75 parts of plant polyose, the life of 10 parts of epidermis
The long factor and 15 parts of angelica extract.The plant polyose is fucoidin.The epidermal growth factor is lyophilized for EGF
Powder.The angelica extract is Radix Angelicae Sinensis water extract, and Ligustilide mass fraction is 1.2%.
The matrix contains 5% light-coloured vinegar, and the matrix pH value is 3.
The externally used coating agent provided in this embodiment for improving the colour of skin is prepared according to the following steps：
(1) according to formula rate dispensing；
(2) soluble ingredient in dispensing is added to mixing in matrix successively and dissolved；
(3) by the non-solubility material pulverizing in formula, 400 mesh sieve is crossed, is added in matrix simultaneously mixing.
By the external application coating agent provided in this embodiment for improving the colour of skin, face 1h is coated, 5 times a week, using goddess in the moon's skin
Robot records are decoded before and using skin condition after 3 weeks, as shown in Fig. 2 and table 2, skin-whitening degree, which has, obviously to be carried
Height has no allergic phenomena.
Table 2
| Use preceding solution code value | Using solving code value after 4 weeks | |
| Whitening degree | 199.633 | 203.702 |
| Color spot | 6.173% | 4.777% |
Embodiment 3
A kind of externally used coating agent improving the colour of skin is facial mask, it includes mass fraction 25% for improving the colour of skin
Active constituent and matrix.
The active constituent includes according to mass fraction：25 parts of whitening active ingredients, 15 parts of cutin metabolic activity ingredients,
And 10 parts of skin resistance improves active constituent；
The whitening active ingredients are：The root of Dahurain angelica Ultramicro-powder of 20 parts of mass fraction, 15 parts of PORIA ALBA Ultramicro-powder, 15 parts
The dimension life of bletilla striata Ultramicro-powder, 15 parts of Rhizoma Atractylodis Macrocephalae Ultramicro-powder Ultramicro-powder, the ursin that mass fraction is 1% and mass fraction 1%
Plain C.
The cutin metabolic activity ingredient includes mature vinegar.
The skin resistance improves active constituent：85 parts of plant polyose, the life of 5 parts of epidermis
The long factor and 10 parts of angelica extract.The plant polyose is astragalus polyose.The epidermal growth factor is lyophilized for EGF
Powder.The angelica extract is Radix Angelicae Sinensis water extract, and Ligustilide mass fraction is 1.2%.
The lactic acid that the matrix contains, the matrix pH value are 5.
The externally used coating agent provided in this embodiment for improving the colour of skin is prepared according to the following steps：
(1) according to formula rate dispensing；
(2) soluble ingredient in dispensing is added to mixing in matrix successively and dissolved；
(3) by the non-solubility material pulverizing in formula, 300 mesh sieve is crossed, is added in matrix simultaneously mixing.
By the external application coating agent provided in this embodiment for improving the colour of skin, face 1h is coated, 5 times a week, using goddess in the moon's skin
Robot records are decoded before and using skin condition after 4 weeks, as shown in Fig. 3 and table 3, skin-whitening degree, which has, obviously to be carried
Height has no allergic phenomena.
Table 3
| Use preceding solution code value | Using solving code value after 4 weeks | |
| Whitening degree | 208.508 | 210.296 |
| Color spot | 6.463% | 6.357% |
As it will be easily appreciated by one skilled in the art that the foregoing is merely illustrative of the preferred embodiments of the present invention, not to
The limitation present invention, all within the spirits and principles of the present invention made by all any modification, equivalent and improvement etc., should all include
Within protection scope of the present invention.
Claims (9)
1. a kind of externally used coating agent improving the colour of skin, which is characterized in that it includes mass fraction 25% to 35% for changing
The active constituent of the kind colour of skin；The active constituent includes according to mass fraction：25 parts to 35 parts of whitening active ingredients, 10 parts extremely
15 parts of cutin metabolic activity ingredient and 5 parts to 10 parts of skin resistance improve active constituent；
The skin resistance improves in active constituent, includes according to mass fraction：75 parts to 85 parts of plant polyose, 5 parts to 10
The epidermal growth factor and 10 parts to 15 parts of angelica extract of part.
2. improving the externally used coating agent of the colour of skin as described in claim 1, which is characterized in that the plant polyose is that Radix Astragali is more
The one or more composition of sugar, tremella polysaccharides, fucoidin.
3. improving the external application coating agent of the colour of skin as claimed in claim 2, which is characterized in that the plant polyose is astragalus polyose
Or fucoidin, preferably astragalus polyose and fucoidin are according to mass ratio 1:2 mixture.
4. improving the externally used coating agent of the colour of skin as described in claim 1, which is characterized in that the angelica extract is in Jehol Ligusticum Rhizome
Ester mass fraction is more than or equal to 1.2% Radix Angelicae Sinensis water extract.
5. improving the externally used coating agent of the colour of skin as described in claim 1, which is characterized in that in the whitening active ingredients, packet
Include 10 parts to 20 parts of the root of Dahurain angelica of mass fraction, 10 parts to 20 parts of PORIA ALBA, 10 parts to 20 parts of the bletilla striata, 10 parts to 20 parts white
Art, the vitamin C of the tyrosine kinase inhibitor that mass fraction is 1% to 3% and mass fraction 1% to 3% or its derivative
Object.
6. improving the externally used coating agent of the colour of skin as claimed in claim 4, which is characterized in that in the whitening active ingredients, packet
Include 10 parts of the root of Dahurain angelica of mass fraction, 10 parts of PORIA ALBA, 10 parts of the bletilla striata, 10 parts of Rhizoma Atractylodis Macrocephalae, the tyrosine that mass fraction is 3%
The Ascorbyl Tetraisopalmitate of kinase inhibitor and mass fraction 3%.
7. improving the externally used coating agent of the colour of skin as described in claim 1, which is characterized in that the cutin metabolic activity is at subpackage
Include the one or more mixing of tartaric acid, salicylic acid.
8. improving the externally used coating agent of the colour of skin as claimed in claim 7, which is characterized in that the cutin metabolic activity ingredient is
Tartaric acid.
9. improving the externally used coating agent of the colour of skin as described in claim 1, which is characterized in that it includes matrix, and the matrix contains
There are light-coloured vinegar, mature vinegar and/or lactic acid, the matrix pH value is between 3 to 5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810451789.0A CN108670886A (en) | 2018-05-12 | 2018-05-12 | A kind of externally used coating agent improving the colour of skin |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810451789.0A CN108670886A (en) | 2018-05-12 | 2018-05-12 | A kind of externally used coating agent improving the colour of skin |
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| Publication Number | Publication Date |
|---|---|
| CN108670886A true CN108670886A (en) | 2018-10-19 |
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| CN201810451789.0A Pending CN108670886A (en) | 2018-05-12 | 2018-05-12 | A kind of externally used coating agent improving the colour of skin |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111202701A (en) * | 2020-03-25 | 2020-05-29 | 余传林 | Whitening skin-care itching-relieving liquid and preparation method thereof |
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2018
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111202701A (en) * | 2020-03-25 | 2020-05-29 | 余传林 | Whitening skin-care itching-relieving liquid and preparation method thereof |
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