CN105521286A - Traditional Chinese medicine composition for treating freckles and chloasma, and preparing method and application of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating freckles and chloasma, and preparing method and application of traditional Chinese medicine composition Download PDF

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Publication number
CN105521286A
CN105521286A CN201410571031.2A CN201410571031A CN105521286A CN 105521286 A CN105521286 A CN 105521286A CN 201410571031 A CN201410571031 A CN 201410571031A CN 105521286 A CN105521286 A CN 105521286A
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chinese medicine
medicine composition
radix angelicae
chloasma
traditional chinese
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CN201410571031.2A
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张爱文
汪君
洪厚林
汪林
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Anhui BBCA Pharmaceutical Co Ltd
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Anhui BBCA Pharmaceutical Co Ltd
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Priority to CN201410571031.2A priority Critical patent/CN105521286A/en
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Abstract

The invention relates to a traditional Chinese medicine composition for treating freckles and chloasma, and a preparing method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following ingredients in parts by weight: 8 to 12g of white poria cocos, 3 to 6g of rhizoma bletillae, 0.2 to 3g of radix angelicae, 1 to 5g of radix angelica sinensis, 1 to 4g of liquorice root and 0.1 to 1.2g of pearl powder. The composition obtained by using the technical scheme can achieve the maximum synergic effect; color spots on the face can be obviously diluted; the allergy probability is greatly reduced; safety and effectiveness are realized; and when the traditional Chinese medicine composition is made into a traditional Chinese medicine preparation or cosmetics, the freckle and chloasma removing effect is obvious.

Description

A kind ofly be used for the treatment of freckle, the Chinese medicine composition of chloasma, preparation method and application thereof
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of freckle, chloasma, belong to technical field of Chinese medicines.
Background technology
Freckle, butterfly spot and chloasma are all the modal skin of face pathological changes of adult female, and main manifestations is face local melanin pigmentation, and much worry is endlessly for this reason per capita.For this reason, the use of the skin-lightening cosmetic that women is special is spread gradually and is come, but in cosmetics, the main component of whitening is heavy metal lead, and life-time service is unfavorable to health.
The traditional Chinese medical science is thought, long speckle is mainly uncomfortable relevant in endocrine on the face, and the speckle dispelling folk prescription of Chinese Traditional Medicine also has a lot, but because of folk prescription processing method too loaded down with trivial details, allow a lot of people hang back.The three white cream that existing market is on sale, come from " this grass product will through meeting ", main component is Poria, the Pseudobulbus Bletillae (Rhizoma Bletillae) and the Radix Angelicae Dahuricae, front available Mel or Ovum Gallus domesticus album is used to reconcile into cream, be mainly used in whitening and speckle dispelling, but because the Radix Angelicae Dahuricae has heliosensitivity, so larger anaphylaxis has appearred in a lot of people in use, therefore the use of this product has had significant limitation.
CN103845277A discloses a kind of natural Chinese medicine facial mask powder and preparation method thereof and facial film, and this natural Chinese medicine facial mask powder comprises the raw material of following mass fraction: Radix Angelicae Sinensis, 7-23; The Radix Angelicae Dahuricae, 3-14; The Radix Paeoniae Alba, 3-13; The Rhizoma Atractylodis Macrocephalae, 17-33; The Pseudobulbus Bletillae (Rhizoma Bletillae), 3-20; Poria, 3-15.And following raw material can be increased further: Fructus Atriplicis Sibiricae, 12-28; Radix Glycyrrhizae, 1-8; Margarita powder, 1-8.By each composition Synergistic, be applicable to all types of skin, for improving various skin problem, as acne, pigmentation and wrinkle etc., and product is without other adding ingredients.But there is following defect in it, as:, easily there is anaphylaxis in (1) Pseudobulbus Bletillae (Rhizoma Bletillae) large usage quantity, (2) facial mask powder also needs oneself to allocate, and uses inconvenience.
Summary of the invention
In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of freckle, chloasma, it is by selecting suitable component, adjustment usage ratio, not only significantly improves facial colour spot, and greatly reduces irritated probability, use, safe and effective.
To achieve these goals, the present invention adopts following technical scheme:
Treat a Chinese medicine composition for freckle, chloasma, obtained by the raw material of following weight portion: Poria 8-12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3-6g, Radix Angelicae Dahuricae 0.2-3g, Radix Angelicae Sinensis 1-5g, Radix Glycyrrhizae 1-4g, Margarita powder 0.1-1.2g.
The present invention filters out the raw material that six kinds have spot-removal function, and adjusts consumption proportion, makes each component play optimum synergistic effect, significantly improves the speckle dispelling of Chinese medicine composition, whitening effect, and the irritated probability of user is significantly reduced.
Preferably, described Chinese medicine composition is obtained by the raw material of following weight portion: Poria 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Angelicae Dahuricae 1g, Radix Angelicae Sinensis 3g, Radix Glycyrrhizae 1.5g, Margarita powder 0.6g.
The present invention also provides the preparation method of above-mentioned Chinese medicine composition, Poria, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Radix Glycyrrhizae, Margarita powder is ground to fine powder respectively, is mixed in proportion, stir.
Wherein, the fineness of fine powder with powder all by No. five sieves, and wherein by No. six sieve powder be no less than 95%.
The present invention also provides above-mentioned Chinese medicine composition preparing the application in medicine for removing speckle.
Described speckle refers to freckle, butterfly spot, chloasma.
The present invention also provides a kind of Chinese medicine preparation, and it contains above-mentioned Chinese medicine composition and pharmaceutically acceptable excipient.
The preferred unguentum of dosage form of described Chinese medicine preparation.
Also containing, for example lower adjuvant in described unguentum: fresh milk, glycerol g, Mel, Ve, ethyl hydroxybenzoate.On the basis of above-mentioned Traditional Chinese medicine composition formula, be aided with the fresh milk of specific consumption, trace V e, glycerol and ethyl hydroxybenzoate, gained unguentum has softening skin, keep moisture, except Lao Pi, enhance metabolism, finally reach the object of skin protection, also have easy to use, the feature of plug and play simultaneously.
As preferred embodiment, the Chinese medicinal ointment for the treatment of freckle of the present invention, chloasma, is obtained by the raw material of following weight portion: Poria 8-12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3-6g, Radix Angelicae Dahuricae 0.2-3g, Radix Angelicae Sinensis 1-5g, Radix Glycyrrhizae 1-4g, Margarita powder 0.1-1.2g, fresh milk 5-30g, glycerol 1-5g, Mel 0.2-2.0g, Ve0.05-0.4g, ethyl hydroxybenzoate 0.02-0.2g.
Further preferably, the Chinese medicinal ointment of described treatment freckle, chloasma, is obtained by the raw material of following weight portion: Poria 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Angelicae Dahuricae 1g, Radix Angelicae Sinensis 3g, Radix Glycyrrhizae 1.5g, Margarita powder 0.6g, fresh milk 10g, glycerol 2g, Mel 0.8g, Ve200mg, ethyl hydroxybenzoate 0.1g.
The present invention also provides the preparation method of above-mentioned unguentum, Poria, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Radix Glycyrrhizae, Margarita powder are ground to fine powder respectively, add fresh milk, glycerol, Mel, Ve, ethyl hydroxybenzoate according to the conventional unguentum preparation order in this area, stir.
The present invention also provides above-mentioned Chinese medicine composition preparing the application in cosmetics.
The present invention is on the basis of the white cream of traditional ancient prescription three, to the Pseudobulbus Bletillae (Rhizoma Bletillae) decrement having heliosensitivity, increase Radix Angelicae Sinensis, Margarita powder, Radix Glycyrrhizae component simultaneously, by each amounts of components relation of Reasonable adjustment, resulting composition can play maximum synergism, not only significantly improves facial colour spot, and greatly reduce irritated probability, safe and effective, it makes Chinese medicine preparation or cosmetics, the remarkable speckle dispelling of speckle dispelling.
Detailed description of the invention
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.
Embodiment 1 one kinds of Chinese medicine compositions
Described Chinese medicine composition is obtained by the raw material of following weight portion: Poria 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Angelicae Dahuricae 1g, Radix Angelicae Sinensis 3g, Radix Glycyrrhizae 1.5g, Margarita powder 0.6g.
Embodiment 2 one kinds of Chinese medicine compositions
Described Chinese medicine composition is obtained by the raw material of following weight portion: Poria 8g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3g, Radix Angelicae Dahuricae 0.2g, Radix Angelicae Sinensis 1g, Radix Glycyrrhizae 1g, Margarita powder 0.1g.
Embodiment 3 one kinds of Chinese medicine compositions
Described Chinese medicine composition is obtained by the raw material of following weight portion: Poria 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g, Radix Angelicae Dahuricae 3g, Radix Angelicae Sinensis 5g, Radix Glycyrrhizae 4g, Margarita powder 1.2g.
Embodiment 4 one kinds of speckle dispelling ointment
Described speckle dispelling ointment is obtained by the raw material of following weight portion: Poria 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Angelicae Dahuricae 1g, Radix Angelicae Sinensis 3g, Radix Glycyrrhizae 1.5g, Margarita powder 0.6g, fresh milk 10g, glycerol 2g, Mel 0.8g, Ve200mg, ethyl hydroxybenzoate 0.1g.
Embodiment 5 one kinds of speckle dispelling ointment
Described speckle dispelling ointment is obtained by the raw material of following weight portion: Poria 8g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3g, Radix Angelicae Dahuricae 0.2g, Radix Angelicae Sinensis 1g, Radix Glycyrrhizae 1g, Margarita powder 0.1g, fresh milk 5g, glycerol 1g, Mel 0.2g, Ve0.05g, ethyl hydroxybenzoate 0.02g.
Embodiment 6 one kinds of speckle dispelling ointment
Described speckle dispelling ointment is obtained by the raw material of following weight portion: Poria 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g, Radix Angelicae Dahuricae 3g, Radix Angelicae Sinensis 5g, Radix Glycyrrhizae 4g, Margarita powder 1.2g, fresh milk 30g, glycerol 5g, Mel 2g, Ve0.4g, ethyl hydroxybenzoate 0.2g.
The preparation method of embodiment 7 one kinds of Chinese medicine compositions
The preparation of Chinese medicine composition described in embodiment 1: Poria, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Radix Glycyrrhizae, Margarita powder are ground to fine powder respectively, by formula mixing, stirs.
Wherein, the fineness of fine powder with powder all by No. five sieves, and wherein by No. six sieve powder be no less than 95%.
The preparation method of embodiment 8 one kinds of speckle dispelling ointment
The preparation of speckle dispelling ointment described in embodiment 4: Poria, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Radix Glycyrrhizae, Margarita powder are ground to fine powder respectively by formula, fresh milk, glycerol, Mel, Ve, the ethyl hydroxybenzoate of formula ratio is added according to the conventional unguentum preparation order in this area, stir, in the vial of tape loaded plug.
Wherein, the fineness of fine powder with powder all by No. five sieves, and wherein by No. six sieve powder be no less than 95%.
Comparative example 1
The facial mask powder formula recorded with [0046] in CN103845277A as a comparison case 1, its concrete formula is: Radix Angelicae Sinensis, 15 parts; The Radix Angelicae Dahuricae, 7.5 parts; The Radix Paeoniae Alba, 7 parts; The Rhizoma Atractylodis Macrocephalae, 25 parts; The Pseudobulbus Bletillae (Rhizoma Bletillae), 11.5 parts; Poria, 9 parts; Fructus Atriplicis Sibiricae, 20 parts; Radix Glycyrrhizae, 4.5 parts; Margarita powder, 4.5 parts.
Compliance test result of the present invention
Experimental example 1
Embodiment 1-6 resulting composition and comparative example 1 are carried out compliance test result experiment, and specific experiment is:
Choose 420 examples and have freckle, chloasma or butterfly spot patient, be divided into 7 groups (embodiment 1 group, embodiment 2 groups, embodiment 3 groups, embodiment 4 groups, embodiment 5 groups, embodiment 6 groups, comparative examples 1 group), often organize 60 examples, patient used each group of corresponding compositions last hour just before going to bed every night, after flush coat after sustainable 20-40min, clean.After 30 days, according to the situation for the treatment of, therapeutic outcome is divided into effectively (without speckle or substantially without speckle), effective (area reduces over half) and invalid (area reduces below half or substantially unchanged), irritated four kinds of situations, concrete outcome is in table 1.
Table 1 freckle effect experimental result
Effectively Effective Invalid Irritated
Embodiment 1 51 6 2 1
Embodiment 2 50 5 3 2
Embodiment 3 48 8 2 2
Embodiment 4 54 3 0 0
Embodiment 5 56 3 1 0
Embodiment 6 55 4 1 0
Comparative example 1 15 14 13 18
As shown in Table 1, described in embodiment of the present invention 1-6, the successful of compositions is better than comparative example 1, and occurs that irritated probability greatly reduces.Particularly the freckle effect of embodiment 4-6 is more outstanding, occurs without allergic phenomena.
Although above the present invention is described in detail with a general description of the specific embodiments, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.

Claims (10)

1. treat a Chinese medicine composition for freckle, chloasma, it is characterized in that, obtained by the raw material of following weight portion: Poria 8-12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3-6g, Radix Angelicae Dahuricae 0.2-3g, Radix Angelicae Sinensis 1-5g, Radix Glycyrrhizae 1-4g, Margarita powder 0.1-1.2g.
2. the Chinese medicine composition for the treatment of freckle according to claim 1, chloasma, is characterized in that, described Chinese medicine composition is obtained by the raw material of following weight portion: Poria 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Angelicae Dahuricae 1g, Radix Angelicae Sinensis 3g, Radix Glycyrrhizae 1.5g, Margarita powder 0.6g.
3. a preparation method for the treatment freckle described in claim 1 or 2, the Chinese medicine composition of chloasma, is characterized in that, Poria, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Radix Glycyrrhizae, Margarita powder are ground to fine powder respectively, are mixed in proportion, stir;
Wherein, the fineness of fine powder with powder all by No. five sieves, and wherein by No. six sieve powder be no less than 95%.
4. the treatment freckle described in claim 1 or 2, the Chinese medicine composition of chloasma are preparing the application in medicine for removing speckle.
5. application according to claim 4, is characterized in that, described speckle refers to freckle, butterfly spot, chloasma.
6. a Chinese medicine preparation, is characterized in that, containing Chinese medicine composition described in claim 1 or 2 and pharmaceutically acceptable excipient.
7. Chinese medicine preparation according to claim 6, is characterized in that, the dosage form of described Chinese medicine preparation is unguentum.
8. Chinese medicine preparation according to claim 7, it is characterized in that, described unguentum is obtained by the raw material of following weight portion: Poria 8-12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3-6g, Radix Angelicae Dahuricae 0.2-3g, Radix Angelicae Sinensis 1-5g, Radix Glycyrrhizae 1-4g, Margarita powder 0.1-1.2g, fresh milk 5-30g, glycerol 1-5g, Mel 0.2-2.0g, Ve0.05-0.4g, ethyl hydroxybenzoate 0.02-0.2g.
9. Chinese medicine preparation according to claim 8, it is characterized in that, described unguentum is obtained by the raw material of following weight portion: Poria 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 5g, Radix Angelicae Dahuricae 1g, Radix Angelicae Sinensis 3g, Radix Glycyrrhizae 1.5g, Margarita powder 0.6g, fresh milk 10g, glycerol 2g, Mel 0.8g, Ve200mg, ethyl hydroxybenzoate 0.1g.
10. the treatment freckle described in claim 1 or 2, the Chinese medicine composition of chloasma are preparing the application in cosmetics.
CN201410571031.2A 2014-10-23 2014-10-23 Traditional Chinese medicine composition for treating freckles and chloasma, and preparing method and application of traditional Chinese medicine composition Pending CN105521286A (en)

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Cited By (6)

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CN105963467A (en) * 2016-06-30 2016-09-28 冯袖幅 Traditional Chinese medicine composition, application thereof and preparation
CN106511707A (en) * 2017-01-11 2017-03-22 曲中周 Traditional Chinese medicine liquid for removing freckles
CN107184810A (en) * 2017-05-19 2017-09-22 安徽陛颜祛斑技术研究有限公司 A kind of whitening spot-removing Chinese medicinal mask powder
CN109200191A (en) * 2018-11-29 2019-01-15 陕西国际商贸学院 Restrain myogenic, Chinese materia medica preparation of light speckles, beautification and white and preparation method thereof
CN113425784A (en) * 2021-07-12 2021-09-24 黔东南民族职业技术学院 Beautifying formula for removing chloasma
CN115154549A (en) * 2022-05-26 2022-10-11 柳州市中医医院(柳州市壮医医院) Preparation method of compound tea oil speckle-removing oil

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105963467A (en) * 2016-06-30 2016-09-28 冯袖幅 Traditional Chinese medicine composition, application thereof and preparation
CN106511707A (en) * 2017-01-11 2017-03-22 曲中周 Traditional Chinese medicine liquid for removing freckles
CN107184810A (en) * 2017-05-19 2017-09-22 安徽陛颜祛斑技术研究有限公司 A kind of whitening spot-removing Chinese medicinal mask powder
CN109200191A (en) * 2018-11-29 2019-01-15 陕西国际商贸学院 Restrain myogenic, Chinese materia medica preparation of light speckles, beautification and white and preparation method thereof
CN113425784A (en) * 2021-07-12 2021-09-24 黔东南民族职业技术学院 Beautifying formula for removing chloasma
CN115154549A (en) * 2022-05-26 2022-10-11 柳州市中医医院(柳州市壮医医院) Preparation method of compound tea oil speckle-removing oil
CN115154549B (en) * 2022-05-26 2023-10-20 柳州市中医医院(柳州市壮医医院) Preparation method of compound tea oil speckle-removing oil

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