CN108096091A - Preventing baldness black hair composition and preparation method containing Cordyceps extract - Google Patents
Preventing baldness black hair composition and preparation method containing Cordyceps extract Download PDFInfo
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
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- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
The present invention proposes preventing baldness black hair composition and preparation method containing Cordyceps extract.Said composition includes：Cordyceps extract, Chinese medical extract, hydrolysis of keratin and yeast extract.Said composition can make hair obtain new life, and with non-stimulated, good absorbing and other effects, compared with the prior art, Anti-hair loss significant effect is more excellent by recovering the physiological function of scalp comprehensively, so as to eliminate alopecia, white hair.
Description
Technical field
The present invention relates to cosmetic field, in particular it relates to the preventing baldness crow containing Cordyceps extract
Send out composition and preparation method.
Background technology
Hair is the important component of human body, and hair generates in hair follicle, and the health status of hair follicle directly determines hair
The health status of hair.With the quickening of modern life rhythm, the operating pressure of people, learning pressure are also constantly being promoted,
Physiological dysfunction is easily lead in the case that long-term stress is excessive, vegetative nerve or nervous centralis function occur disorderly
Disorderly, make the nutrition function of motion in papilla ball top portion that obstacle occur, therefore the synthesis of hair keratoprotein can not be carried out, hair is female thin
Born of the same parents lose vigor, and cause alopecia, shave one's head and white hair etc. prematurely occur.
Therefore, seek it is a kind of can be with Anti-hair loss, hair tonic, black hair and mild non-stimulated, product that the good effect of absorbability is good just
Become particularly significant.
The content of the invention
It is presently disclosed on hair tonic, black hair technical literature in, all more or less there are less effective, irritation are big
The technical issues of, the application is intended to solve the above problem of the prior art at least to a certain extent.For this purpose, the present invention proposes
A kind of composition, said composition, so as to eliminate alopecia, white hair, can make hair by recovering the physiological function of scalp comprehensively
New life is obtained, and with non-stimulated, good absorbing and other effects, compared with the prior art, Anti-hair loss significant effect is more excellent.
In the first aspect of the present invention, the present invention proposes a kind of composition.According to an embodiment of the invention, the combination
Object, including：Cordyceps extract, Chinese medical extract, hydrolysis of keratin and yeast extract, wherein, the cordyceps sinensis
Extract obtains in the following way：(1) it is 1 in mass ratio with water by cordyceps sinensis or cordyceps mycelia powder:20~
30 ratio mixing, constant temperature filters after stirring extraction 30~100 minutes in 20~100 DEG C of water-baths；(2) solid adds in after filtering
The glycerine of same step (1) water phase homogenous quantities and the mixed liquor of water extract, the constant temperature stirring extraction 30 in 20~100 DEG C of water-baths
It is filtered after~100 minutes, merges the filtrate extracted twice, the wherein volume ratio of glycerine and water is 1:20~50；(3) by (2) institute
The filtrate obtained is filtered, by filtrate and glycerine after being concentrated in vacuo to 10~50 times of cordyceps sinensis or erinaceus mycelium powder quality after centrifugation
In mass ratio 1:0.5~3 is uniformly mixed, and Cordyceps extract is made.The Chinese medical extract is made by following Chinese medicine material：
Cacumen biotae, the fleece-flower root, folium artemisiae argyi, Rhizoma Chuanxiong, the fruit of glossy privet, Semen Cuscutae, kuh-seng, Radix Glycyrrhizae part and Chinese prickly ash.Inventor has found that utilization is above-mentioned
The Cordyceps extract master of method extraction can give hair containing amino acid, polysaccharide, cordycepic acid and various trace elements etc.
Stem cell provides good nutrient environment, remarkably promotes scared growth, while also has immunological regulation, boosts metabolism,
Improve the effect of microcirculation.The hair-growing effects of the composition prepared by Cordyceps extract obtained using aforesaid way are better than
The Cordyceps extract obtained using other manner.Composition according to embodiments of the present invention can be by recovering scalp comprehensively
Physiological function, so as to eliminate alopecia, white hair, hair is made to obtain new life, and with non-stimulated, good absorbing and other effects, compared to
The prior art, Anti-hair loss significant effect are more excellent.
According to an embodiment of the invention, above-mentioned composition further comprises at least one following additional technical feature：
According to an embodiment of the invention, the parts by weight of the Cordyceps extract be the parts by weight of 2.0 parts by weight~6.0,
The parts by weight of Chinese medical extract are the parts by weight of 10.0 parts by weight~30.0, the parts by weight of hydrolysis of keratin are 0.5 parts by weight~2.0
Parts by weight and the parts by weight of yeast extract are the parts by weight of 0.5 parts by weight~2.0.Hydrolysis of keratin contains the Guang ammonia of high-content
Acid and glutamic acid, are hair ultimate constituents, necessary nutrition are provided for the growth of hair, promote and improve the work of hair
Power accelerates the update of scalp cells；Yeast extract has superior sebum rich in very abundant water-soluble B vitamin
Secrete managerial ability；Cordyceps extract master can give hair containing amino acid, polysaccharide, cordycepic acid and various trace elements etc.
Dry cell provides good nutrient environment, promotes scared growth, while also has immunological regulation, boosts metabolism,
Improve the effect of microcirculation；Different Chinese medicines in Chinese medicine extract can play different functions.Inventor has found that above-mentioned composition exists
Under conditions of above-mentioned parts by weight, it can cooperate with and play the role of black hair, hair tonic, there is significant advantage especially in terms of Anti-hair loss.
According to an embodiment of the invention, the Chinese medical extract includes：The cacumen biotae of 10~30 parts by weight, 10~30 weight
The fleece-flower root, the folium artemisiae argyi of 15~35 parts by weight, the Rhizoma Chuanxiong of 5~20 parts by weight, the fruit of glossy privet, 5~20 weights of 10~25 parts by weight of part
Measure the Semen Cuscutae of part, the kuh-seng of 2~10 parts by weight, the Radix Glycyrrhizae part of 2~10 parts by weight and the Chinese prickly ash of 1~5 parts by weight.Arbor-vitae
Leaf：The effect of cool blood suppression fat, growing and blacking hair, while there is bacteriostasis, energy anti-dandruff promotes hair restoration, enhances hair follicle
Metabolic function；The fleece-flower root：Liver-kidney tonifying, nourishing the blood to expel wind, replenishing qi and blood, nourishing hair promote hair melanin to generate, and make hair black
Dark hair is bright, is easy to comb；Folium artemisiae argyi：Bitterly, warm-natured, qi-regulating promoting circulation of blood can effectively inhibit bacteria growth, clean scalp, pitch-black
Hair；The fruit of glossy privet：It is sweet in flavor, mild-natured, nourishing liver and kidney, the improving eyesight of energy, for kidney deficiency, graying of hair；Rhizoma Chuanxiong：Head blood capillary can be expanded
Pipe, promotes blood circulation, and increases trichotrophy, white hair is delayed to generate, and hair is kept to moisten gloss, prevents disconnected hair and alopecia；Tu
Silk：Warming kidney and enhancing body, cold dispelling controlling nocturnal emission with astringent drugs, tonifies the liver and kidney, puckery essence anticreep.Hair follicle can be nourished, strengthen the hair anticreep promotes hair growth；
Kuh-seng：Cool blood qi-regulating, clearing heat and expelling damp, while there is sterilizing and itch-relieving, inhibit scalp bacterium and largely grow, alleviate scalp scabies
Itch reaction；Chinese prickly ash：Blood-activating and qi-promoting makes normal circulation of qi and blood, improves local circulation；Radix Glycyrrhizae：Nourishing qi and blood, coordinating the drug actions of a prescription.Cacumen biotae, Chinese mugwort
The ingredients such as leaf, kuh-seng play an important role of sterilizing and itch-relieving, inhibit scalp bacterium and largely grow, and alleviate itching of the scalp reaction；The worm summer in winter
The ingredients such as the careless extract cooperation fleece-flower root, Semen Cuscutae, the fruit of glossy privet play an important role of to tonify the liver and kidney, controlling nocturnal emission with astringent drugs hair care, and long-time service can
To improve white hair, alopecia etc.；Rhizoma Chuanxiong, in addition the pungent scattered promoting the circulation of qi of pepper, makes normal circulation of qi and blood, can improve local circulation with blood circulation promoting and enriching.
Inventor has found that Cordyceps extract compounds above-mentioned 9 kinds of Chinese herbal medicine extracts, plays not same-action respectively, comprehensively solve is current
The hair problem of appearance.
It should be noted that Chinese medical extract described herein, yeast extract and hydrolysis of keratin can pass through root
It prepares according to the extraction process or routine of the embodiment of the present invention, is also commercially available.
According to a particular embodiment of the invention, the Chinese medical extract can obtain in the following way：By Chinese medicine material
It is mixed with 65% ethanol solution progress first, the first filtration treatment, obtains the first extracting solution；The weight of the ethanol solution is institute
State Chinese medicine material weight 3~6 times, first mixed processing are that progress 0.5~1.5 is small under the conditions of temperature is 30~50 DEG C
When；Filter residue after first filtering with distilled water progress second is mixed, the second filtration treatment, obtain the second extracting solution；The steaming
The weight of distilled water is 6~8 times of the filter residue weight, second mixed processing be carry out 1 under the conditions of temperature is 100 DEG C~
3 it is small when；First extracting solution with the second extracting solution progress the 3rd is mixed, stands, concentrate, aseptic filtration processing, so as to
Obtain the Chinese medical extract, the stewing process be carried out under conditions of temperature is 4~6 DEG C 12~24 it is small when, it is described dense
The weight of contracting treated Chinese medical extract is 1~3 times of the Chinese medicine material weight.Inventor has found, utilizes the above method
Chinese medical extract is prepared, efficient, easy to operate, extraction active ingredient is more.
According to an embodiment of the invention, the composition further comprises medicine or cosmetic field acceptable figuration
Agent.
According to an embodiment of the invention, the composition in spray, lotion, liniment, ointment, tablet, injection, pulvis,
Elixir, capsule, suspension, syrup, pill or thin slice.
In the second aspect of the present invention, the present invention proposes a kind of composition.According to an embodiment of the invention, the combination
Object includes：The parts by weight of 2.0 parts by weight of Cordyceps extract~6.0, the parts by weight of 10.0 parts by weight of Chinese medical extract~30.0, water
Solve the parts by weight of keratin 0.5 parts by weight~2.0, the parts by weight of 0.5 parts by weight of yeast extract~2.0, wherein, the cordyceps sinensis
Extract obtains in the following way：(1) it is 1 in mass ratio with water by cordyceps sinensis or cordyceps mycelia powder:20~
30 ratio mixing, constant temperature filters after stirring extraction 30~100 minutes in 20~100 DEG C of water-baths；(2) solid adds in after filtering
The glycerine of same step (1) water phase homogenous quantities and the mixed liquor of water extract, the constant temperature stirring extraction 30 in 20~100 DEG C of water-baths
It is filtered after~100 minutes, merges the filtrate extracted twice, the wherein volume ratio of glycerine and water is 1:20~50；(3) by (2) institute
The filtrate obtained is filtered, by filtrate and glycerine after being concentrated in vacuo to 10~50 times of cordyceps sinensis or erinaceus mycelium powder quality after centrifugation
In mass ratio 1:0.5~3 is uniformly mixed, and Cordyceps extract is made；Wherein, the Chinese medical extract is in the following way
It obtains：
By Chinese medicine material：The cacumen biotae of 10~30 parts by weight, the fleece-flower root of 10~30 parts by weight, the Chinese mugwort of 15~35 parts by weight
Leaf, the Rhizoma Chuanxiong of 5~20 parts by weight, the fruit of glossy privet of 10~25 parts by weight, the Semen Cuscutae of 5~20 parts by weight, the hardship of 2~10 parts by weight
Ginseng, the Radix Glycyrrhizae part of 2~10 parts by weight and the Chinese prickly ash of 1~5 parts by weight mix, the first mistake with 65% ethanol solution progress first
Filter is handled, and obtains the first extracting solution；The weight of the ethanol solution is 3~6 times of the Chinese medicine material weight, and described first is mixed
Conjunction processing is when progress 0.5~1.5 is small under the conditions of temperature is 30~50 DEG C；Filter residue after first filtering is carried out with distilled water
Second mixing, the second filtration treatment, obtain the second extracting solution；The weight of the distilled water is 6~8 times of the filter residue weight,
Second mixed processing is when progress 1~3 is small under the conditions of temperature is 100 DEG C；First extracting solution is carried with second
Liquid is taken to carry out the 3rd mixing, stand, concentrate, aseptic filtration processing, to obtain the Chinese medical extract, the stewing process is
Temperature for carry out under conditions of 4~6 DEG C 12~24 it is small when, during the weight of the Chinese medical extract after the concentration is described
1~3 times of medicine raw material weight.Inventor has found, using the Cordyceps extract master of above method extraction containing amino acid, more
Sugar, cordycepic acid and various trace elements etc., can give hair stem cells and provide good nutrient environment, promote scared
Growth, while also there is immunological regulation, boost metabolism, improve the effect of microcirculation.Hydrolysis of keratin contains high-content
Cystine and glutamic acid are hair ultimate constituents, provide necessary nutrition for the growth of hair, promote and improve hair
Vigor accelerates the update of scalp cells；Yeast extract has superior skin rich in very abundant water-soluble B vitamin
Fat secretes managerial ability；Cacumen biotae：The effect of cool blood suppression fat, growing and blacking hair, while there is bacteriostasis, energy anti-dandruff promotees
Into hair restoration, enhance hair follicle metabolism function；The fleece-flower root：Liver-kidney tonifying, nourishing the blood to expel wind, replenishing qi and blood, nourishing hair promote hair
Melanin generate, make hair it is pitch-black it is shinny, be easy to comb；Folium artemisiae argyi：Bitterly, warm-natured, qi-regulating promoting circulation of blood can be inhibited bacteria effectively
It grows, cleans scalp, pitch-black hair；The fruit of glossy privet：It is sweet in flavor, mild-natured, nourishing liver and kidney, the improving eyesight of energy, for kidney deficiency, graying of hair；River
Rhizome of chuanxiong：Head capillary can be expanded, promoted blood circulation, increase trichotrophy, white hair is delayed to generate, hair is kept to moisten light
Pool prevents disconnected hair and alopecia；Semen Cuscutae：Warming kidney and enhancing body, cold dispelling controlling nocturnal emission with astringent drugs, tonifies the liver and kidney, puckery essence anticreep.Hair follicle can be nourished, Gu
Anticreep is sent out, promotes hair growth；Kuh-seng：Cool blood qi-regulating, clearing heat and expelling damp, while there is sterilizing and itch-relieving, it is thin to inhibit scalp
Bacterium largely grows, and alleviates itching of the scalp reaction；Chinese prickly ash：Blood-activating and qi-promoting makes normal circulation of qi and blood, improves local circulation；Radix Glycyrrhizae：QI invigorating is supported
Blood, coordinating the drug actions of a prescription.Inventor has found that Cordyceps extract compounds above-mentioned 9 kinds of Chinese herbal medicine extracts, plays not same-action respectively,
The hair problem that comprehensively solve occurs at present.The ingredients such as cacumen biotae, folium artemisiae argyi, kuh-seng play an important role of sterilizing and itch-relieving, inhibit scalp
Bacterium largely grows, and alleviates itching of the scalp reaction；The ingredients tools such as the Cordyceps extract cooperation fleece-flower root, Semen Cuscutae, the fruit of glossy privet
It tonifies the liver and kidney, controlling nocturnal emission with astringent drugs hair care, long-time service can improve white hair, alopecia etc.；Rhizoma Chuanxiong can be with blood circulation promoting and enriching, in addition recklessly
The pungent scattered promoting the circulation of qi of green pepper makes normal circulation of qi and blood, improves local circulation.The group prepared by Cordyceps extract obtained using aforesaid way
The hair-growing effects for closing object are better than the Cordyceps extract obtained using other manner.Composition energy according to embodiments of the present invention
Enough physiological functions by recovering scalp comprehensively so as to eliminate alopecia, white hair, make hair obtain new life, and with non-stimulated, suction
Keep well and other effects, there is significant advantage especially in terms of Anti-hair loss.
In the third aspect of the present invention, the present invention proposes a kind of spray mixture.According to an embodiment of the invention, it is described
Spray mixture includes foregoing composition.Spray mixture according to embodiments of the present invention is suitable for filling in aerosol can
Spray use is made, it is easy to use, and, so as to eliminate alopecia, white hair, can be made by recovering the physiological function of scalp comprehensively
Hair obtains new life, and with non-stimulated, good absorbing and other effects, it is significantly more excellent in terms of Anti-hair loss.
According to an embodiment of the invention, above-mentioned spray mixture further comprises at least one following additional technical feature：
According to an embodiment of the invention, the spray mixture further comprises, the parts by weight of 0.05 parts by weight~0.30
Thickener, the moisturizer of the parts by weight of 4.0 parts by weight~12.0, the bright peptide antimicrobial fluid of the parts by weight of 2.0 parts by weight~5.0.Inventor
It was found that above-mentioned composition can be so that above-mentioned composition uniformly mixes within the scope of above-mentioned parts by weight, formation is suitable for the mixing of spraying
Liquid.And the bright peptide antimicrobial fluid of plant fermentation product changes big antibacterial of traditional irritation such as previous Form aldehyde release body class as bacteriostatic agent
Agent.Spray mixture according to embodiments of the present invention can be by recovering the physiological function of scalp comprehensively, so as to eliminate alopecia, white
Hair makes hair obtain new life, and with non-stimulated, good absorbing and other effects, it is significantly more excellent in terms of Anti-hair loss.
According to an embodiment of the invention, the thickener is included selected from hydroxyethyl cellulose, xanthans, carbomer and poly-
At least one of sodium acrylate.
According to an embodiment of the invention, the moisturizer is included selected from glycerine, 1,3-BDO, 1,3-PD, dipropyl
At least one of glycol and sorbierite.
The entitled bright string coccus/radish root tunning filtrates of INCI are the equivalent skill of bright peptide antimicrobial fluid of the present invention
Art feature alternatively uses mutually and reaches effect of the present invention, in the case of no special instruction, such equivalent skill
Art feature belongs to the scope of protection of the invention.
In the fourth aspect of the present invention, the present invention proposes a kind of method for preparing spray mixture.It is according to the present invention
Embodiment, the described method includes：By water, Cordyceps extract, Chinese medical extract, hydrolysis of keratin and yeast extract into
Row mixed processing, to obtain the spray mixture, wherein, the dosage of the Cordyceps extract for 2.0 parts by weight~
6.0 parts by weight；The dosage of the Chinese medical extract is the parts by weight of 10.0 parts by weight~30.0；The dosage of the hydrolysis of keratin is
The parts by weight of 0.5 parts by weight~2.0；The dosage of the yeast extract is the parts by weight of 0.5 parts by weight~2.0.Wherein, the winter worm
Summer grass extract obtains in the following way：(1) it is 1 in mass ratio with water by cordyceps sinensis or cordyceps mycelia powder:
20~30 ratio mixing, constant temperature filters after stirring extraction 30~100 minutes in 20~100 DEG C of water-baths；(2) solid after filtering
The mixed liquor of the glycerine and water that add in same step (1) water phase homogenous quantities extracts, and constant temperature is stirred and carried in 20~100 DEG C of water-baths
It is filtered after taking 30~100 minutes, merges the filtrate extracted twice, the wherein volume ratio of glycerine and water is 1:20~50；(3) will
(2) filtrate obtained by is filtered after being concentrated in vacuo to 10~50 times of cordyceps sinensis or erinaceus mycelium powder quality after centrifugation, by filtrate with
Glycerine in mass ratio 1:0.5~3 is uniformly mixed, and Cordyceps extract is made.Inventor has found, utilizes above method extraction
Cordyceps extract master can give hair stem cells offer containing amino acid, polysaccharide, cordycepic acid and various trace elements etc.
Good nutrient environment promotes scared growth, while also has immunological regulation, boosts metabolism, and improves microcirculation
Effect.Hydrolysis of keratin contains the cystine and glutamic acid of high-content, is hair ultimate constituent, is provided for the growth of hair
Necessary nutrition promotes and improves the vigor of hair, accelerates the update of scalp cells；Yeast extract is rich in very abundant water
Dissolubility B family vitamin has superior sebum secretion managerial ability；Cordyceps extract master is containing amino acid, polysaccharide, cordyceps sinensis
Acid and various trace elements etc., can give hair stem cells and provide good nutrient environment, promote scared growth, together
When also have immunological regulation, boost metabolism, improve the effect of microcirculation；Different Chinese medicines in Chinese medicine extract can play not
Same function.Inventor has found that above-mentioned composition can cooperate under conditions of above-mentioned parts by weight and play the role of black hair, hair tonic, especially
It is significantly more excellent in terms of Anti-hair loss.The spray mixture being prepared according to the method for the embodiment of the present invention can be by comprehensive
Recover the physiological function of scalp, so as to eliminate alopecia, white hair, hair made to obtain new life, and with it is non-stimulated, good absorbing is equivalent
Fruit, it is significantly more excellent in terms of Anti-hair loss.
According to an embodiment of the invention, the above method further comprises at least one following additional technical feature：
According to an embodiment of the invention, the method is further included by moisturizer, thickener and bright peptide antimicrobial fluid with
Water, Cordyceps extract, Chinese medical extract, hydrolysis of keratin, yeast extract carry out mixed processing, wherein, the thickening
The dosage of agent is the parts by weight of 0.05 parts by weight~0.30, and the dosage of the moisturizer is the parts by weight of 4.0 parts by weight~12.0, described
The dosage of bright peptide antimicrobial fluid is the parts by weight of 2.0 parts by weight~5.0.Inventor has found that above-mentioned composition is in the range of above-mentioned parts by weight
Can be so that above-mentioned composition uniformly mix, formation is suitable for the mixed liquor of spraying.And the bright peptide antimicrobial fluid conduct of plant fermentation product
Bacteriostatic agent changes the big bacteriostatic agent of traditional irritation such as previous Form aldehyde release body class.It prepares and obtains according to the method for the embodiment of the present invention
Spray mixture, so as to eliminate alopecia, white hair, hair can be made to obtain newly by recovering the physiological function of scalp comprehensively
It is raw, and with non-stimulated, good absorbing and other effects, it is significantly more excellent in terms of Anti-hair loss.
According to an embodiment of the invention, the Chinese medical extract includes：The cacumen biotae of 10~30 parts by weight, 10~30 weight
The fleece-flower root, the folium artemisiae argyi of 15~35 parts by weight, the Rhizoma Chuanxiong of 5~20 parts by weight, the fruit of glossy privet, 5~20 weights of 10~25 parts by weight of part
Measure the Semen Cuscutae of part, the kuh-seng of 2~10 parts by weight, the Radix Glycyrrhizae part of 2~10 parts by weight and the Chinese prickly ash of 1~5 parts by weight.Arbor-vitae
Leaf：The effect of cool blood suppression fat, growing and blacking hair, while there is bacteriostasis, energy anti-dandruff promotes hair restoration, enhances hair follicle
Metabolic function；The fleece-flower root：Liver-kidney tonifying, nourishing the blood to expel wind, replenishing qi and blood, nourishing hair promote hair melanin to generate, and make hair black
Dark hair is bright, is easy to comb；Folium artemisiae argyi：Bitterly, warm-natured, qi-regulating promoting circulation of blood can effectively inhibit bacteria growth, clean scalp, pitch-black
Hair；The fruit of glossy privet：It is sweet in flavor, mild-natured, nourishing liver and kidney, the improving eyesight of energy, for kidney deficiency, graying of hair；Rhizoma Chuanxiong：Head blood capillary can be expanded
Pipe, promotes blood circulation, and increases trichotrophy, white hair is delayed to generate, and hair is kept to moisten gloss, prevents disconnected hair and alopecia；Tu
Silk：Warming kidney and enhancing body, cold dispelling controlling nocturnal emission with astringent drugs, tonifies the liver and kidney, puckery essence anticreep.Hair follicle can be nourished, strengthen the hair anticreep promotes hair growth；
Kuh-seng：Cool blood qi-regulating, clearing heat and expelling damp, while there is sterilizing and itch-relieving, inhibit scalp bacterium and largely grow, alleviate scalp scabies
Itch reaction；Chinese prickly ash：Blood-activating and qi-promoting makes normal circulation of qi and blood, improves local circulation；Radix Glycyrrhizae：Nourishing qi and blood, coordinating the drug actions of a prescription.Invention human hair
Existing, Cordyceps extract compounds above-mentioned 9 kinds of Chinese herbal medicine extracts, plays not same-action, the head that comprehensively solve occurs at present respectively
Question is inscribed.The ingredients such as cacumen biotae, folium artemisiae argyi, kuh-seng play an important role of sterilizing and itch-relieving, inhibit scalp bacterium and largely grow, alleviate scalp
Itch is reacted；The Cordyceps extract cooperation fleece-flower root, Semen Cuscutae, the ingredients such as the fruit of glossy privet have tonify the liver and kidney, controlling nocturnal emission with astringent drugs hair care
Effect, long-time service can improve white hair, alopecia etc.；Rhizoma Chuanxiong can be with blood circulation promoting and enriching, in addition the pungent scattered promoting the circulation of qi of pepper, makes qi and blood smooth
It is logical, improve local circulation.
According to an embodiment of the invention, the mixed processing carries out in the following way：1) by the moisturizer, increasing
Thick dose and first part of the 4th mixing of water progress, homogeneous, cooling treatment, obtain the 4th mixed liquor；2) toward the 4th mixed liquor
It is middle to add in the Cordyceps extract, Chinese medical extract, hydrolysis of keratin, yeast extract, bright peptide antimicrobial fluid and second
Part water carries out the 5th mixed processing, to obtain the spray mixture, wherein, the water includes first part of water and described
Second part of water.Inventor has found, first mixes part water with moisturizer, thickener, can be uniformly mixed it, add the winter afterwards
Worm summer grass extract, Chinese medical extract, hydrolysis of keratin, yeast extract, bright peptide antimicrobial fluid and remaining water, can preferably make
It obtains active ingredient to be uniformly dispersed in water, so as to obtain being suitable as the mixed liquor of spraying.
According to an embodiment of the invention, the 4th mixed processing is carried out under conditions of temperature is 80~85 DEG C
10min's.Inventor has found that under conditions of the above-mentioned temperature above-mentioned time, thickener, moisturizer can fully disperse in water
It opens.
According to an embodiment of the invention, the homogenization is carried out 2 minutes under conditions of speed is 500r/min.
According to an embodiment of the invention, the temperature that the cooling processing is is 48 DEG C.Inventor has found, cools to above-mentioned temperature
Degree adds Cordyceps extract, Chinese medical extract, hydrolysis of keratin, yeast extract, and bright peptide antibacterial liquid energy prevents wherein
Some active ingredients are rotten because high temperature causes.
According to an embodiment of the invention, further comprise that pH adjustings are handled after the 5th mixed processing, treated for adjusting
PH is 5.5~6.5.Inventor has found that pH is under the slightly acidic environment of 5.5~6.5 suitable hair growths, is suitble to long-time service,
Situations such as improving the white hair of hair, shaving one's head.
According to an embodiment of the invention, the Chinese medical extract obtains in the following way：By Chinese medicine material with
65% ethanol solution carries out the first mixing, the first filtration treatment, obtains the first extracting solution；The weight of the ethanol solution is described
3~6 times of Chinese medicine material weight, first mixed processing are that progress 0.5~1.5 is small under the conditions of temperature is 30~50 DEG C
When；Filter residue after first filtering with distilled water progress second is mixed, the second filtration treatment, obtain the second extracting solution；The steaming
The weight of distilled water is 6~8 times of the filter residue weight, second mixed processing be carry out 1 under the conditions of temperature is 100 DEG C~
3 it is small when；First extracting solution with the second extracting solution progress the 3rd is mixed, stands, concentrate, aseptic filtration processing, so as to
Obtain the Chinese medical extract, the stewing process be carried out under conditions of temperature is 4~6 DEG C 12~24 it is small when, it is described dense
The weight of contracting treated Chinese medical extract is 1~3 times of the Chinese medicine material weight.Inventor has found, utilizes the above method
Chinese medical extract is prepared, efficient, easy to operate, extraction active ingredient is more.
According to an embodiment of the invention, the method for the present invention for preparing spray mixture is included moisturizer, thickener
And water mixing, 80~85 DEG C are heated with stirring to, keeps the temperature 10 minutes；After heat preservation, homogeneous is opened, homogeneous speed is 500r/
Min, homogenizing time are 2 minutes, stirring cooling；It treats that temperature is cooled to 48 DEG C, adds in Cordyceps extract, Chinese medical extract,
Hydrolysis of keratin, yeast extract, bright peptide antimicrobial fluid, supply distilled water ad pond om 100 parts, regulation system pH 5.5~
Between 6.5, stir evenly.
In the fifth aspect of the present invention, the present invention proposes a kind of spraying device.According to an embodiment of the invention, the spray
Mist device includes foregoing spray mixture or the spray mixture being prepared according to foregoing method；And
Aerosol can, the spray mixture are potted in the aerosol can.Spraying device according to embodiments of the present invention, it is easy to use,
Chinese medicine species is more, non-stimulated, so as to eliminate alopecia, white hair, can obtain hair by recovering the physiological function of scalp comprehensively
New life, and with non-stimulated, good absorbing and other effects.With the significantly more preferably Anti-hair loss effect of product compared with the prior art.
The advantageous effect of the present invention is at least one described below：
(1) composition of the invention selects Cordyceps extract to compound 9 kinds of Chinese herbal medicine extracts, plays different works respectively
With the hair problem that comprehensively solve occurs at present.The ingredients such as cacumen biotae, folium artemisiae argyi, kuh-seng play an important role of sterilizing and itch-relieving, inhibit head
Skin bacterium largely grows, and alleviates itching of the scalp reaction；The ingredients such as the Cordyceps extract cooperation fleece-flower root, Semen Cuscutae, the fruit of glossy privet
Play an important role of to tonify the liver and kidney, controlling nocturnal emission with astringent drugs hair care, long-time service can improve white hair, alopecia etc.；Rhizoma Chuanxiong can with blood circulation promoting and enriching, in addition
The pungent scattered promoting the circulation of qi of pepper makes normal circulation of qi and blood, improves local circulation.Cordyceps extract in the composition of the present invention compounds 9 kinds
Chinese herbal medicine extract, cooperates between extract and collaboration promotes, and significant advantage is shown in terms of epilation is prevented.
(2) spraying device according to embodiments of the present invention is easy to use, is sprayed directly on to scalp, without washing, safety
It is non-stimulated；The bright peptide antimicrobial fluid of plant fermentation product is selected to change the tradition thorn such as previous Form aldehyde release body class as bacteriostatic agent in formula
Swash the big bacteriostatic agent of property.
(3) no added hormone and antibiotic, product pH are maintained at suitable in spray mixture according to embodiments of the present invention
Under the slightly acidic environment of hair growth, it is suitble to long-time service, situations such as improving the white hair of hair, shave one's head.
Specific embodiment
The embodiment of the present invention is described below in detail.The following examples are exemplary, it is intended to for explaining the present invention,
And it is not considered as limiting the invention.
Cordyceps extract used in the present embodiment is using a kind of patented technology CN 104546657A " winters used for cosmetic
The method provided in the extracting method of worm summer grass active matter " is made." (1) presses cordyceps sinensis or cordyceps mycelia powder with water
Mass ratio is 1:20~30 ratio mixing, constant temperature filters after stirring extraction 30~100 minutes in 20~100 DEG C of water-baths；(2)
The mixed liquor of glycerine and water that solid adds in same step (1) water phase homogenous quantities extracts after filtering, in 20~100 DEG C of water-baths
Constant temperature stirring extraction is filtered after 30~100 minutes, merges the filtrate extracted twice, and the wherein volume ratio of glycerine and water is 1:20~
50；(3) filtrate obtained by (2) is filtered after being concentrated in vacuo to 10~50 times of cordyceps sinensis or erinaceus mycelium powder quality after centrifugation,
By filtrate and glycerine in mass ratio 1:0.5~3 is uniformly mixed, and Cordyceps extract is made；Cordyceps sinensis or mycelium in step (1)
The granularity of powder is 40~100 mesh；Filtering is handled using 0.22um filter membranes in step (3).”
Other raw materials can be obtained by commercially available purchase.
The preparation method of spray mixture is as described below：
Moisturizer, thickener and distilled water are subjected to mixed processing, are heated with stirring to 80~85 DEG C, keeps the temperature 10 minutes；
After heat preservation, homogeneous 2 minutes, stirring cooling under conditions of speed is 500r/min by mixed liquor；
It treats that temperature is cooled to 48 DEG C, adds in Cordyceps extract, Chinese medical extract, hydrolysis of keratin, yeast extract,
Bright peptide antimicrobial fluid supplies distilled water to 100 parts by weight, and regulation system pH is stirred evenly between 5.5~6.5, to obtain
State spray mixture.
As described below is the preferred embodiment of the present invention, and what the present invention was protected is not limited to the following side of being preferably implemented
Formula.It should be pointed out that for those skilled in the art on the basis of this innovation and creation design, several deformations for making and
It improves, belongs to protection scope of the present invention, in order to further describe the present invention, illustrate below by specific embodiment.
Embodiment 1
It is prepared by cordyceps extracting liquid
(1) weigh 20.0g drying cordyceps sinensis and be crushed to 40 mesh, powder is 1 in mass ratio with water:20 ratio mixing,
Constant temperature stirring extraction is filtered after 30 minutes in 20 DEG C of water-baths；
(2) solid adds in the glycerine of same step (1) water phase homogenous quantities and the mixed liquor of water after filtering, permanent in 20 DEG C of water-baths
It is filtered after temperature stirring 30 clocks of extraction, merges the filtrate extracted twice, the wherein volume ratio of glycerine and water is 1:20；
(3) filter vacuum obtained by (2) is concentrated into 10 times of Cordyceps sinensis powder quality, then is centrifuged through 6000r/min
The processing of 0.22um filter membranes is crossed after twenty minutes, and filtrate is with glycerine with 1:0.5 mass ratio mixing obtains final cordyceps sinensis extraction
Liquid.The effective component extraction rate of this embodiment is 83.61%.
Embodiment 2
(1) weigh 20.0g drying cordyceps sinensis and be crushed to 100 mesh, powder is 1 in mass ratio with water:30 ratio mixing,
Constant temperature stirring extraction is filtered after 100 minutes in 100 DEG C of water-baths；
(2) solid adds in the glycerine of same step (1) water phase homogenous quantities and the mixed liquor of water after filtering, in 100 DEG C of water-baths
It is filtered after constant temperature stirring 100 clocks of extraction, merges the filtrate extracted twice, the wherein volume ratio of glycerine and water is 1:50；
(3) filter vacuum obtained by (2) is concentrated into 50 times of Cordyceps sinensis powder quality, then is centrifuged through 12000r/min
The processing of 0.22um filter membranes is crossed after twenty minutes, and filtrate is with glycerine with 1:3 mass ratio mixing, obtains final cordyceps extracting liquid.
The effective component extraction rate of this embodiment is 90.32%.
Embodiment 3
(1) weigh 20.0g drying cordyceps sinensis and be crushed to 60 mesh, powder is 1 in mass ratio with water:25 ratio mixing,
Constant temperature stirring extraction is filtered after 80 minutes in 80 DEG C of water-baths；
(2) solid adds in the glycerine of same step (1) water phase homogenous quantities and the mixed liquor of water after filtering, permanent in 80 DEG C of water-baths
It is filtered after temperature stirring 80 clocks of extraction, merges the filtrate extracted twice, the wherein volume ratio of glycerine and water is 1:30；
(3) filter vacuum obtained by (2) is concentrated into 30 times of Cordyceps sinensis powder quality, then is centrifuged through 8000r/min
The processing of 0.22um filter membranes is crossed after twenty minutes, and filtrate is with glycerine with 1:1 mass ratio mixing, obtains final cordyceps extracting liquid.
The effective component extraction rate of this embodiment is 92.08%.
Embodiment 4
(1) weigh 20.0g drying cordyceps sinensis and be crushed to 80 mesh, powder is 1 in mass ratio with water:28 ratio mixing,
Constant temperature stirring extraction is filtered after sixty minutes in 60 DEG C of water-baths；
(2) solid adds in the glycerine of same step (1) water phase homogenous quantities and the mixed liquor of water after filtering, permanent in 60 DEG C of water-baths
It is filtered after temperature stirring 60 clocks of extraction, merges the filtrate extracted twice, the wherein volume ratio of glycerine and water is 1:40；
(3) filter vacuum obtained by (2) is concentrated into 40 times of Cordyceps sinensis powder quality, then is centrifuged through 10000r/min
The processing of 0.22um filter membranes is crossed after twenty minutes, and filtrate is with glycerine with 1:2 mass ratio mixing, obtains final cordyceps extracting liquid.
The effective component extraction rate of this embodiment is 89.66%.
Embodiment 5
(1) weigh 20.0g drying cordyceps sinensis and be crushed to 50 mesh, powder is 1 in mass ratio with water:22 ratio mixing,
Constant temperature stirring extraction is filtered after 50 minutes in 50 DEG C of water-baths；
(2) solid adds in the glycerine of same step (1) water phase homogenous quantities and the mixed liquor of water after filtering, permanent in 50 DEG C of water-baths
It is filtered after temperature stirring 50 clocks of extraction, merges the filtrate extracted twice, the wherein volume ratio of glycerine and water is 1:25；
(3) filter vacuum obtained by (2) is concentrated into 25 times of Cordyceps sinensis powder quality, then is centrifuged through 8000r/min
The processing of 0.22um filter membranes is crossed after twenty minutes, and filtrate is with glycerine with 1:1.5 mass ratio mixing obtains final cordyceps sinensis extraction
Liquid.The effective component extraction rate of this embodiment is 91.58%.
Embodiment 6
A kind of Anti-hair loss containing Cordyceps extract in the present embodiment, hair tonic, black hair spraying, be by it is following by weight
The raw material of part is prepared, and is shown in Table 1：
Table 1：
| Raw material | It matches (%) |
| Cordyceps extract | 2.0 |
| Chinese medical extract | 15.0 |
| Hydrolysis of keratin | 0.50 |
| Yeast extract | 2.0 |
| Thickener | 0.10 |
| Moisturizer | 12.0 |
| Bright peptide antimicrobial fluid | 2.0 |
| Water | 66.4 |
Its preparation process is：
(1) preparation of Chinese medicine extract：
Chinese medicine extract is prepared by the Chinese medicine material of following proportioning by weight：
10 parts of cacumen biotae, 20 parts of the fleece-flower root, 35 parts of folium artemisiae argyi, 10 parts of Rhizoma Chuanxiong, 20 parts of the fruit of glossy privet, 15 parts of Semen Cuscutae, kuh-seng 2
Part, 10 parts of Radix Glycyrrhizae, 3 parts of Chinese prickly ash.
(2) traditional Chinese medicine extraction
The Chinese medicine material of above-mentioned weight fraction is crushed into 20 mesh of sieving, adds in 4 times of 65% ethanol water of Chinese herbal medicine weight
Solution, when 35 DEG C of conditions extraction 1 is small after, an extracting solution is obtained by filtration；Filter residue adds in 6 times of distilled water heating and boils extraction 2
Hour, filter residue is filtered to remove, merges the filtrate obtained twice, when standing 24 is small at 4 DEG C, Aspirate supernatant is simultaneously concentrated into original
1.5 times of medicine weight obtain Chinese medicine extract after aseptic filtration.
(3) preparation of product
The distilled water of 0.1g thickeners, 12.0g moisturizer and 66.4g is weighed, is heated with stirring to 80~85 DEG C of sterilizings；Stir knot
Shu Hou opens homogeneous, and homogeneous speed is 500r/min, and homogenizing time is 2 minutes, stirring cooling；It treats that temperature is cooled to 48 DEG C, adds
Enter 2.0g Cordyceps extracts (embodiment 2 be made), add above-mentioned 15.0g Chinese medical extracts, 0.5g hydrolysis of keratin,
2.0g yeast extracts, the bright peptide antimicrobial fluids of 2.0g, regulation system pH are stirred evenly 6.0, saturating up to brown color after the assay was approved
Open-birth hair, black hair spray liquid.
Product is mildly non-stimulated, related without there are the products such as red swelling of the skin, shouting pain, itch, scorching hot during on probation
Adverse reaction.
Embodiment 7
A kind of Anti-hair loss containing Cordyceps extract in the present embodiment, hair tonic, black hair spraying, be by it is following by weight
The raw material of part is prepared, and is shown in Table 2：
Table 2：
| Raw material | It matches (%) |
| Cordyceps extract | 6.0 |
| Chinese medical extract | 10.0 |
| Hydrolysis of keratin | 1.0 |
| Yeast extract | 1.5 |
| Thickener | 0.05 |
| Moisturizer | 6.0 |
| Bright peptide antimicrobial fluid | 5.0 |
| Water | 70.45 |
Its preparation process is：
(1) preparation of Chinese medicine extract：
Chinese medicine extract is prepared by following proportioning Chinese medicine material by weight：
30 parts of cacumen biotae, 10 parts of the fleece-flower root, 15 parts of folium artemisiae argyi, 15 parts of Rhizoma Chuanxiong, 15 parts of the fruit of glossy privet, 20 parts of Semen Cuscutae, kuh-seng 8
Part, 8 parts of Radix Glycyrrhizae, 1 part of Chinese prickly ash
Cordyceps extracting liquid is made by embodiment 3.
Other steps are same as Example 6.
Product is mildly non-stimulated, related without there are the products such as red swelling of the skin, shouting pain, itch, scorching hot during on probation
Adverse reaction.
Embodiment 8
A kind of Anti-hair loss containing Cordyceps extract in the present embodiment, hair tonic, black hair spraying, be by it is following by weight
The raw material of part is prepared, and is shown in Table 3：
Table 3：
| Raw material | It matches (%) |
| Cordyceps extract | 4.0 |
| Chinese medical extract | 30.0 |
| Hydrolysis of keratin | 1.5 |
| Yeast extract | 1.0 |
| Thickener | 0.30 |
| Moisturizer | 4.0 |
| Bright peptide antimicrobial fluid | 3.0 |
| Water | 56.2 |
Its preparation process is：
(1) preparation of Chinese medicine extract：
Chinese medicine extract is prepared by following proportioning Chinese medicine material by weight：
25 parts of cacumen biotae, 30 parts of the fleece-flower root, 30 parts of folium artemisiae argyi, 5 parts of Rhizoma Chuanxiong, 10 parts of the fruit of glossy privet, 10 parts of Semen Cuscutae, 6 parts of kuh-seng,
4 parts of Radix Glycyrrhizae, 5 parts of Chinese prickly ash
Cordyceps extracting liquid is made by embodiment 5.
Other steps are same as Example 6.
Product is mildly non-stimulated, related without there are the products such as red swelling of the skin, shouting pain, itch, scorching hot during on probation
Adverse reaction.
Embodiment 9
A kind of Anti-hair loss containing Cordyceps extract in the present embodiment, hair tonic, black hair spraying, be by it is following by weight
The raw material of part is prepared, and is shown in Table 4：
Table 4：
| Raw material | It matches (%) |
| Cordyceps extract | 5.0 |
| Chinese medical extract | 20.0 |
| Hydrolysis of keratin | 2.0 |
| Yeast extract | 0.5 |
| Thickener | 0.18 |
| Moisturizer | 8.0 |
| Bright peptide antimicrobial fluid | 2.5 |
| Water | 61.82 |
Its preparation process is：
(1) preparation of Chinese medicine extract：
Chinese medicine extract is prepared by following proportioning Chinese medicine material by weight：
20 parts of cacumen biotae, 25 parts of the fleece-flower root, 25 parts of folium artemisiae argyi, 20 parts of Rhizoma Chuanxiong, 25 parts of the fruit of glossy privet, 5 parts of Semen Cuscutae, kuh-seng 10
Part, 6 parts of Radix Glycyrrhizae, 4 parts of Chinese prickly ash
Cordyceps extracting liquid is made by embodiment 4.
Other steps are same as Example 6.
Product is mildly non-stimulated, related without there are the products such as red swelling of the skin, shouting pain, itch, scorching hot during on probation
Adverse reaction.
Comparative example 1
Comparative example 1 is prepared, and comparative example ingredient is as follows：
Table 5：
| Raw material | It matches (%) |
| Chinese medical extract | 20.0 |
| Hydrolysis of keratin | 2.0 |
| Yeast extract | 0.5 |
| Thickener | 0.18 |
| Moisturizer | 8.0 |
| Bright peptide antimicrobial fluid | 2.5 |
| Water | 66.82 |
The concrete configuration method of comparative example is the same as embodiment 6.
By the preventing baldness black hair spraying that the embodiment of the present invention 6 obtains and the preventing baldness black hair that comparative example obtains
Spraying carries out following Efficacy experiments：
Choose the volunteer that 60 average alopecia numbers are more than 100 pieces/day；It is divided into 2 groups, every group of 30 people, experimental group is sent out with this
Product prepared by the formula of bright embodiment 6, the product that control group is prepared with comparative example.Spraying is once in the morning and once at night sprayed on head
Pi Shang, and carry out the massage of 3~5 minutes.Experimental period is 3 months, and volunteer is the 0th day, 4 weeks, 8 weeks in implementation process is tested
It was paid a return visit with 12 weeks.
1. the effect of Anti-hair loss
Volunteer carries out daily 2 combing hair tests sooner or later, collects the hair to come off and counting, is taken after average value is obtained
Its integer.
Table 6：Hair is averaged alopecia number
From the above result shows that：Can be with the increase of usage time using the product of the present invention, the effect of Anti-hair loss is brighter；
Compared with the control group compared with being substantially reduced using the product alopecia number that is averaged of the present invention.
2. antibacterial, antipruritic effect comparison
Table 7：Bacterio static itching-relieving effect (number)
| Classification | It is effective | Effectively | Improve | It is invalid |
| Experimental group | 21 | 5 | 3 | 1 |
| Control group | 17 | 4 | 5 | 4 |
As can be seen from the above results, product of the invention has the effect of certain bacterio static itching-relieving, and obvious effective rate can reach
To 70%, total effective rate can reach 86.7%.
3. the comparison of the dense improvement degree of hair
Table 8：The dense improvement degree comparison of hair
| Classification | Hair is substantially dense | Hair moderate is dense | Hair is slightly dense | It is invalid |
| Experimental group | 24 | 3 | 1 | 2 |
| Control group | 20 | 4 | 2 | 4 |
It it can be seen from the results above that the product of the present invention has the effect of hair tonic, can increase the dense degree of hair,
Product is with obvious effects to be better than control group, and effective percentage can reach 90%
4. the Contrast on effect of hair black hair
Table 9：The Contrast on effect of hair black hair
| Classification | Black hair is with obvious effects | Moderate black hair effect | Slightly black hair effect | It is invalid |
| Experimental group | 26 | 3 | 1 | 0 |
| Control group | 21 | 3 | 3 | 3 |
It can be seen from the results above that the product of the present invention can make newborn hair color blackening, there is apparent black hair
Effect, obvious effective rate also reach 86.7%, and newborn hair quality also has some improvement and improves.
Comparative example 2
Comparative example 2 matches somebody with somebody such as table 10, preparation method with embodiment 6,
Table 10：
| Raw material | It matches (%) |
| Cordyceps extract | 1.0 |
| Chinese medical extract | 15.0 |
| Hydrolysis of keratin | 0.50 |
| Yeast extract | 2.0 |
| Thickener | 0.10 |
| Moisturizer | 12.0 |
| Bright peptide antimicrobial fluid | 2.0 |
| Water | 67.4 |
Inhibit it was found that the Anti-hair loss of embodiment 6, black hair, hair tonic are sprayed in terms of trichomadesis better than comparative example 2.
Comparative example 3
Comparative example 3 matches somebody with somebody such as table 11, preparation method with embodiment 6,
Table 11：
Inhibit it was found that the Anti-hair loss of embodiment 6, black hair, hair tonic are sprayed in terms of trichomadesis better than comparative example 3.
Comparative example 4
Comparative example 4 matches somebody with somebody such as table 12, preparation method with embodiment 6,
Table 12：
| Raw material | It matches (%) |
| Cordyceps extract | 2.0 |
| Chinese medical extract | 8.0 |
| Hydrolysis of keratin | 0.50 |
| Yeast extract | 2.0 |
| Thickener | 0.10 |
| Moisturizer | 12.0 |
| Bright peptide antimicrobial fluid | 2.0 |
| Water | 73.4 |
Inhibit it was found that the Anti-hair loss of embodiment 6, black hair, hair tonic are sprayed in terms of trichomadesis better than comparative example 4.
Comparative example 5
Comparative example 5 matches somebody with somebody such as table 13, preparation method with embodiment 6,
Table 13：
Inhibit it was found that the Anti-hair loss of embodiment 6, black hair, hair tonic are sprayed in terms of trichomadesis better than comparative example 5.
In summary embodiment and comparative example, a kind of hair tonic containing Cordyceps extract according to embodiments of the present invention
It is engaged, acted synergistically with 9 kinds of extracts of Chinese herbal medicine using cordyceps extracting liquid in black hair spraying, there is significant inhibition hair
The effect of falling out.Growing and blacking hair spraying according to embodiments of the present invention simultaneously containing Cordyceps extract, it is micro- improving
Xun Huan promotes hair growth, makes hair restoration and blackening, antibacterial, antipruritic, also has advantage in terms of improving hair hair quality.Product
It is mild non-stimulated, without there is the relevant adverse reaction of the products such as red swelling of the skin, shouting pain, itch, scorching hot during on probation.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or the spy for combining the embodiment or example description
Point is contained at least one embodiment of the present invention or example.In the present specification, schematic expression of the above terms is not
It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office
It is combined in an appropriate manner in one or more embodiments or example.In addition, without conflicting with each other, the skill of this field
Art personnel can tie the different embodiments described in this specification or example and different embodiments or exemplary feature
It closes and combines.
Although the embodiment of the present invention has been shown and described above, it is to be understood that above-described embodiment is example
Property, it is impossible to limitation of the present invention is interpreted as, those of ordinary skill in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, changes, replacing and modification.
Claims (10)
1. a kind of composition, which is characterized in that including：Cordyceps extract, Chinese medical extract, hydrolysis of keratin and yeast
Extract,
Wherein, the Cordyceps extract obtains in the following way：
(1) it is 1 in mass ratio with water by cordyceps sinensis or cordyceps mycelia powder:20~30 ratio mixing, at 20~100 DEG C
Constant temperature stirring extraction is filtered after 30~100 minutes in water-bath；
(2) mixed liquor of glycerine and water that solid adds in same step (1) water phase homogenous quantities extracts after filtering, 20~100
Constant temperature stirring extraction is filtered after 30~100 minutes in DEG C water-bath, merges the volume ratio of the filtrate, wherein glycerine and water extracted twice
For 1:20~50；
(3) by the filtrate obtained by (2) after being concentrated in vacuo to 10~50 times of cordyceps sinensis or erinaceus mycelium powder quality, mistake after centrifugation
Filter, by filtrate and glycerine in mass ratio 1:0.5~3 is uniformly mixed, and Cordyceps extract is made；
The Chinese medical extract is made by following Chinese medicine material：Cacumen biotae, the fleece-flower root, folium artemisiae argyi, Rhizoma Chuanxiong, the fruit of glossy privet, Semen Cuscutae, hardship
Ginseng, Radix Glycyrrhizae and Chinese prickly ash.
2. composition according to claim 1, which is characterized in that the parts by weight of the Cordyceps extract are 2.0 weights
The parts by weight of part~6.0, the parts by weight of Chinese medical extract are measured as the parts by weight of 10.0 parts by weight~30.0, the parts by weight of hydrolysis of keratin
Parts by weight for the parts by weight of 0.5 parts by weight~2.0 and yeast extract are the parts by weight of 0.5 parts by weight~2.0.
3. composition according to claim 1, which is characterized in that the Chinese medical extract is made by following Chinese medicine material：
The cacumen biotae of 10~30 parts by weight, the fleece-flower root of 10~30 parts by weight, the folium artemisiae argyi of 15~35 parts by weight, 5~20 parts by weight
Rhizoma Chuanxiong, the fruit of glossy privet of 10~25 parts by weight, the Semen Cuscutae of 5~20 parts by weight, the kuh-seng of 2~10 parts by weight, 2~10 parts by weight
Radix Glycyrrhizae part and 1~5 parts by weight Chinese prickly ash.
4. according to claim 1-3 any one of them compositions, which is characterized in that the Chinese medical extract is by such as lower section
What formula obtained：
Chinese medicine material with 65% ethanol solution progress first is mixed, the first filtration treatment, obtain the first extracting solution；The ethyl alcohol
The weight of solution is 3~6 times of the Chinese medicine material weight, and first mixed processing is under the conditions of temperature is 30~50 DEG C
When progress 0.5~1.5 is small；
Filter residue after first filtering with distilled water progress second is mixed, the second filtration treatment, obtain the second extracting solution；The steaming
The weight of distilled water is 6~8 times of the filter residue weight, second mixed processing be carry out 1 under the conditions of temperature is 100 DEG C~
3 it is small when；
First extracting solution with the second extracting solution progress the 3rd is mixed, stands, concentrate, aseptic filtration processing, to obtain
The Chinese medical extract, the stewing process are when progress 12~24 is small under conditions of temperature is 4~6 DEG C, at the concentration
The weight of Chinese medical extract after reason is 1~3 times of the Chinese medicine material weight.
5. composition according to claim 1, which is characterized in that further comprise that medicine or cosmetic field can receive
Excipient；
Optionally, the composition in spray, lotion, liniment, ointment, tablet, injection, pulvis, elixir, capsule, suspension,
Syrup, pill or thin slice.
6. a kind of composition, which is characterized in that including：
The parts by weight of 2.0 parts by weight of Cordyceps extract~6.0,
The parts by weight of 10.0 parts by weight of Chinese medical extract~30.0,
The parts by weight of 0.5 parts by weight of hydrolysis of keratin~2.0,
The parts by weight of 0.5 parts by weight of yeast extract~2.0,
Wherein, the Cordyceps extract obtains in the following way：
(1) it is 1 in mass ratio with water by cordyceps sinensis or cordyceps mycelia powder:20~30 ratio mixing, at 20~100 DEG C
Constant temperature stirring extraction is filtered after 30~100 minutes in water-bath；
(2) mixed liquor of glycerine and water that solid adds in same step (1) water phase homogenous quantities extracts after filtering, 20~100
Constant temperature stirring extraction is filtered after 30~100 minutes in DEG C water-bath, merges the volume ratio of the filtrate, wherein glycerine and water extracted twice
For 1:20~50；
(3) by the filtrate obtained by (2) after being concentrated in vacuo to 10~50 times of cordyceps sinensis or erinaceus mycelium powder quality, mistake after centrifugation
Filter, by filtrate and glycerine in mass ratio 1:0.5~3 is uniformly mixed, and Cordyceps extract is made；
Wherein, the Chinese medical extract obtains in the following way：
By Chinese medicine material：The cacumen biotae of 10~30 parts by weight, the fleece-flower root of 10~30 parts by weight, the folium artemisiae argyi of 15~35 parts by weight, 5
The Rhizoma Chuanxiong of~20 parts by weight, the fruit of glossy privet of 10~25 parts by weight, the Semen Cuscutae of 5~20 parts by weight, the kuh-seng of 2~10 parts by weight, 2
The Radix Glycyrrhizae part of~10 parts by weight and the Chinese prickly ash of 1~5 parts by weight carry out first with 65% ethanol solution and mix, at the first filtering
Reason, obtains the first extracting solution；The weight of the ethanol solution is 3~6 times of the Chinese medicine material weight, at first mixing
Reason is when progress 0.5~1.5 is small under the conditions of temperature is 30~50 DEG C；
Filter residue after first filtering with distilled water progress second is mixed, the second filtration treatment, obtain the second extracting solution；The steaming
The weight of distilled water is 6~8 times of the filter residue weight, second mixed processing be carry out 1 under the conditions of temperature is 100 DEG C~
3 it is small when；
First extracting solution with the second extracting solution progress the 3rd is mixed, stands, concentrate, aseptic filtration processing, to obtain
The Chinese medical extract, the stewing process are when progress 12~24 is small under conditions of temperature is 4~6 DEG C, at the concentration
The weight of Chinese medical extract after reason is 1~3 times of the Chinese medicine material weight.
7. a kind of spray mixture, which is characterized in that include claim 1~6 any one of them composition.
8. spray mixture according to claim 7, which is characterized in that further comprise,
The thickener of the parts by weight of 0.05 parts by weight~0.30,
The moisturizer of the parts by weight of 4.0 parts by weight~12.0,
The bright peptide antimicrobial fluid of the parts by weight of 2.0 parts by weight~5.0.
9. a kind of preparation method of spray mixture, which is characterized in that the spray mixture such as claim 7 or 8 is limited
, including：
Moisturizer, thickener and distilled water are subjected to mixed processing, are heated with stirring to 80~85 DEG C, keeps the temperature 10 minutes；
After heat preservation, homogeneous 2 minutes, stirring cooling under conditions of speed is 500r/min by mixed liquor；
It treats that temperature is cooled to 48 DEG C, adds in Cordyceps extract, Chinese medical extract, hydrolysis of keratin, yeast extract, bright peptide
Antimicrobial fluid supplies distilled water to 100 parts by weight, and regulation system pH is stirred evenly between 5.5~6.5, to obtain the spray
Mist mixed liquor.
10. a kind of spraying device, which is characterized in that including：Claim 7-8 any one of them spray mixture or according to power
Profit requires the method described in 9 to obtain spray mixture；And
Aerosol can, the spray mixture are potted in the aerosol can.
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| CN108901615A (en) * | 2018-07-19 | 2018-11-30 | 保定学院 | Utilize the method for trollflower pharmacological property culture medium culture cordyceps mycelium |
| CN110051608A (en) * | 2019-06-06 | 2019-07-26 | 重庆戴贺李生物科技有限公司 | Anticreep hair care containing crocus sativus is sprayed essence and preparation method |
| CN111329981A (en) * | 2020-02-25 | 2020-06-26 | 澳宝化妆品（惠州）有限公司 | Antibacterial, anti-inflammatory and blood circulation-promoting microcapsule Chinese herbal medicine composition and preparation method thereof |
| CN111529445A (en) * | 2020-05-27 | 2020-08-14 | 广州有望生物科技有限公司 | Plant hair dye |
| CN115252528A (en) * | 2021-04-29 | 2022-11-01 | 代晓丽 | Preparation method of nourishing hair care liquid |
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| CN1706437A (en) * | 2005-05-27 | 2005-12-14 | 王家军 | Combined Chinese and Western medicine liniment for treating seborrheic baldness |
| CN103751082A (en) * | 2011-12-31 | 2014-04-30 | 青岛艾华隆生物科技有限公司 | Spraying agent capable of nourishing and protecting hair |
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| JP2003292422A (en) * | 2002-04-01 | 2003-10-15 | Noevir Co Ltd | Hair cosmetic |
| CN1706437A (en) * | 2005-05-27 | 2005-12-14 | 王家军 | Combined Chinese and Western medicine liniment for treating seborrheic baldness |
| CN103751082A (en) * | 2011-12-31 | 2014-04-30 | 青岛艾华隆生物科技有限公司 | Spraying agent capable of nourishing and protecting hair |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108901615A (en) * | 2018-07-19 | 2018-11-30 | 保定学院 | Utilize the method for trollflower pharmacological property culture medium culture cordyceps mycelium |
| CN110051608A (en) * | 2019-06-06 | 2019-07-26 | 重庆戴贺李生物科技有限公司 | Anticreep hair care containing crocus sativus is sprayed essence and preparation method |
| CN111329981A (en) * | 2020-02-25 | 2020-06-26 | 澳宝化妆品（惠州）有限公司 | Antibacterial, anti-inflammatory and blood circulation-promoting microcapsule Chinese herbal medicine composition and preparation method thereof |
| CN111529445A (en) * | 2020-05-27 | 2020-08-14 | 广州有望生物科技有限公司 | Plant hair dye |
| CN115252528A (en) * | 2021-04-29 | 2022-11-01 | 代晓丽 | Preparation method of nourishing hair care liquid |
| CN115252528B (en) * | 2021-04-29 | 2023-08-18 | 温州卡莲娜贸易有限公司 | Anti-hair loss hair care essence and preparation method thereof |
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| CN108096091B (en) | 2021-03-02 |
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Effective date of registration: 20200522 Address after: 512700 East sunshine industry of milk Town, Ruyuan County, Shaoguan, Guangdong Applicant after: RUYUAN NANLING HAOSHAN HAOSHUI COSMETICS Co.,Ltd. Applicant after: Dongguan dongyangguang cosmetics R & D Co., Ltd Address before: 523000 Dongguan Songshan Lake Science and Technology Industrial Park, Guangdong Applicant before: SUNSHINE LAKE PHARMA Co.,Ltd. Applicant before: RUYUAN NANLING HAOSHAN HAOSHUI COSMETICS Co.,Ltd. |
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Effective date of registration: 20211213 Address after: Room 302, building 32, 368 Zhen'an Middle Road, Chang'an Town, Dongguan City, Guangdong Province 523871 Patentee after: Dongguan dongyangguang Cordyceps research and Development Co.,Ltd. Address before: 512700 East Sunshine Industry Co., Ltd., Rucheng Town, Ruyuan County, Shaoguan City, Guangdong Province Patentee before: RUYUAN NANLING HAOSHAN HAOSHUI COSMETICS CO.,LTD. Patentee before: Dongguan dongyangguang cosmetics R & D Co., Ltd |