CN109512744B - Eyelash growth liquid and preparation method thereof - Google Patents
Eyelash growth liquid and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract
The invention discloses an eyelash growth liquid which comprises the following components in parts by weight: 60-90 parts of water, 0.5-1 part of hydrolyzed silk, 1-5 parts of eyelash peptide, 1-5 parts of carnosine, 4-20 parts of plant extract, 0.1-0.8 part of polyethylene glycol 90M, 5-15 parts of propylene glycol and 0.1-1 part of preservative. According to the invention, the protein is supplemented by the eyelash peptide and the carnosine, the blood activating effects of the four extracting solutions are combined at the same time, the root of the hair is stimulated, and the abundant amino acid in the hydrolyzed silk is utilized, so that the eyelashes can grow better and become thicker and longer.
Description
Technical Field
The invention relates to the field of cosmetics, and particularly relates to eyelash growth liquid and a preparation method thereof.
Background
Eyelashes grow on the anterior lip of the eyelid margin and are arranged in 2-3 rows, short and curved; the upper eyelash is large and long, usually 100 and 150 eyelash, the length is 8-12mm on average, and the eyelash grows slightly upwards and forwards. Generally, the inclination of the eyelids of a person is 79.8% of the male at 110-130 degrees in an eye-open state and 83.5% of the male at 140-160 degrees in an eye-closed state, and the eyelashes are protected by the same female and male, and long eyelashes are oriented by each girl. Slender, curved, dark, flickering and energetic eyelashes beautify the eyes, so that the whole appearance has an important role. The eyelashes are arranged in a semi-arc shape. The eyelashes can set off the outline of the eyes and add to the verve of the eyes. The upper eyelid eyelashes are longer and denser than the lower eyelid eyelashes. The face beauty is black, bright and slightly upwarping, and the face beauty becomes one of important modification parts of human, especially female faces. Therefore, people often beautify eyelashes by applying mascara, sticking false eyelashes, curling eyelashes, and double eyelid surgery. However, the eyelash is not changed, and the eyelash is not lengthened after being washed, and the injury to the eyes is likely to happen.
The method of simply applying vitamin E or olive oil to promote the growth of eyelashes is popular at present, but the effect is not obvious, fat particles are easy to generate, and skin injury around the eyes is caused by serious cases, so that inflammation is caused. Therefore, there is a need to develop an eyelash grower which can not only promote eyelash growth but also leave no damage to the skin around the eyes.
Disclosure of Invention
The invention aims to provide eyelash growth liquid and a preparation method thereof, which utilize eyelash peptide and carnosine to supplement protein, combine the blood activating effect of four extracting solutions to stimulate the root of hair, and utilize abundant amino acid in hydrolyzed silk to enable eyelashes to grow better.
In order to achieve the purpose, the invention adopts the following scheme:
an eyelash growth liquid comprises the following components in parts by weight: 60-90 parts of water, 0.5-1 part of hydrolyzed silk, 1-5 parts of eyelash peptide, 1-5 parts of carnosine, 4-20 parts of plant extract and 0.1-0.8 part of polyethylene glycol 90M.
Preferably, the eyelash growth liquid also comprises the following components in parts by weight: 5-15 parts of propylene glycol and 0.1-1 part of preservative.
Preferably, the plant extract comprises the following components in parts by weight: 1-5 parts of pseudo-ginseng extract, 1-5 parts of poria cocos extract, 1-5 parts of fructus cnidii extract and 1-5 parts of salvia miltiorrhiza extract.
Preferably, the eyelash growth liquid comprises the following components in parts by weight: 70-80 parts of water, 0.5-1 part of hydrolyzed silk, 3-5 parts of eyelash peptide, 2-3 parts of carnosine, 2-3 parts of pseudo-ginseng extract, 2-3 parts of poria cocos extract, 2-3 parts of fructus cnidii extract, 2-3 parts of salvia miltiorrhiza extract, 0.2-0.5 part of polyethylene glycol 90M, 8-12 parts of propylene glycol and 0.1-0.5 part of preservative.
Preferably, the water used is deuterium-depleted water having a D/H ratio of 30 to 50 ppm.
Preferably, the preservative is one or more selected from caprylhydroxamic acid, 1, 2-hexanediol, p-hydroxyacetophenone and 1, 2-pentanediol.
The eyelash peptide is also called myristoyl pentapeptide-17, is a five-peptide effective in promoting eyelash growth, and can directly activate keratin gene so as to make eyelash grow and become thick. The main component of eyelash is cutin, which is 85% -90% of hair shaft, and the cutin is composed of amino acid. The eyelash growth cycle is divided into three phases: transition from growth (i.e., active phase, about 30 days) through the degenerative phase (about 15 days) to the resting phase (about 100 days). The control of eyelash growth cycle is related to the complex interaction between two tissues of hair papilla and hair papilla, which can promote eyelash growth due to the nerve contained in hair papilla and the blood supply for supplying nutrition to eyelash, and can significantly promote eyelash growth to make eyelash grow thicker and thicker if eyelash grower containing myristoyl pentapeptide-17 is continuously used for 7 days.
The hydrolyzed silk is hydrolyzed silk protein and is extracted from natural silk by a special process, so the composition and the content of amino acid are one of important indexes for measuring the quality of products; the hydrolyzed silk protein has good biocompatibility, can be prepared into materials with various forms such as films, gels, microcapsules and the like, and is widely researched in the field of biomedical materials due to the unique physical and chemical properties of the hydrolyzed silk protein, such as immobilized enzyme materials, cell culture matrixes, drug sustained-release agents, artificial organs and the like. The hydrolyzed silk protein contains seventeen kinds of amino acids, wherein the amino acids needed by human body almost have, especially the content of the nutritional amino acids (glycine, alanine, serine, tyrosine) which are very needed by human skin and hair accounts for more than 80% of the total amount of the amino acids, which is not accessible by other hydrolyzed protein.
Carnosine: the scientific name of beta-alanyl-L-histidine is a crystalline solid composed of a dipeptide composed of two amino acids, beta-alanine and L-histidine. Carnosine has a significant inhibitory effect on lipid oxidation caused by free radicals and metal ions. The carnosine can prevent the generation of free radicals generated by smoking, which are more harmful to the skin than sunlight, and the free radicals are atoms or atomic groups with strong activity in the human body and can oxidize other substances in the human body. Carnosine also has antioxidant properties and is a natural antioxidant.
Extracting pseudo-ginseng: contains saponins mainly including ginsenoside Rb1, Rg1, Rg2 and small amount of ginsenoside Ra, Rb2, Rb and Re. In addition, it also contains flavonoid glycoside, starch, protein, oil, etc.; has effects in promoting blood circulation, dispelling blood stasis, removing blood stasis, stopping bleeding, improving and strengthening microcirculation of coronary artery, relieving inflammation, relieving fatigue, resisting tumor, relieving pain, and regulating immunity.
Extracting the poria cocos: the effective components are as follows: pachyman; the functional indications are as follows: induce diuresis and drain dampness, invigorate spleen and calm heart. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia. Has effects in improving physiological activity, stimulating immune system function, inducing and promoting interferon and leukocyte regulatory factor, resisting virus and tumor, relieving side effects of radiotherapy and chemotherapy, protecting liver, reducing transaminase, delaying aging, tranquilizing mind, invigorating stomach, and caring skin.
Fructus cnidii extracting solution: the fructus Cnidii extract is extracted from fruit of fructus Cnidii of Umbelliferae, and has effective components including pinene, isovalerian borneol ester, parsley methyl ether, dihydrocarveol, bergapten, osthole, and isoanisic apigenin, etc., and has effects of clearing heat, eliminating dampness, dispelling pathogenic wind, and relieving itching.
Extracting the salvia miltiorrhiza: the main components are as follows: tanshinone IIA, salvianolic acid B, cryptotanshinone; the Saviae Miltiorrhizae radix extract mainly contains liposoluble non-quinone pigment compounds, such as tanshinone IIA, tanshinone IIB, cryptotanshinone and its isomer. And water soluble phenolic acid components such as protocatechualdehyde and tanshinol. Wherein cryptotanshinone is an antibacterial effective component; has effects of promoting blood circulation, removing blood stasis, regulating qi-flowing and relieving pain.
The mutual compatibility principle is as follows: the plant extract comprises Notoginseng radix extract, Poria extract, fructus Cnidii extract, and Saviae Miltiorrhizae radix extract; sanqi can remove blood stasis to stop bleeding, and also activate blood and dissipate blood stasis. Poria cocos is commonly called poria cocos, pine poria cocos and poria cocos wolf, and ancient people refer to poria cocos as a four-season Shen medicine because of its very wide efficacy, and has the effects of calming heart, soothing nerves, detoxifying and resisting cancers. The medicine has mild property, can remove dampness without damaging vital qi, is compatible with various medicines for various seasons, and can play the unique effect regardless of cold, warm, wind and dampness. Cnidium fruit has the functions of clearing heat, drying dampness, dispelling wind and arresting itching. The Saviae Miltiorrhizae radix has effects of promoting blood circulation, removing blood stasis, regulating qi-flowing and relieving pain. The four traditional Chinese medicines are mixed in proportion, so that the blood circulation is promoted, the blood stasis is removed, the heat is removed, the dampness is eliminated, and the hydrolyzed silk, the eyelash peptide and the carnosine are better used for promoting the hair growth.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring and heating water, polyethylene glycol 90M and propylene glycol to obtain an emulsion A;
(2) cooling, adding hydrolyzed silk, eyelash peptide and carnosine, and stirring;
(3) cooling, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract and antiseptic, stirring, discharging, aging, and inspecting to obtain eyelash growth liquid.
Preferably, in the step (1), the stirring time is 10-20min, and the temperature is heated to 80-85 ℃.
Preferably, in the step (2), when the temperature is reduced to 40-45 ℃, hydrolyzed silk, eyelash peptide and carnosine are added; the stirring time is 10-20 min.
Preferably, in the step (3), the temperature is continuously reduced to 36-39 ℃, the stirring time is 10-15min, and the aging time is 15-30 min.
The invention has the beneficial effects that:
1. according to the invention, the protein is supplemented by the eyelash peptide and the carnosine, the blood activating effects of the four extracting solutions are combined at the same time, the root of the hair is stimulated, and the abundant amino acid in the hydrolyzed silk is utilized, so that the eyelashes can grow better and become thicker and longer.
2. The invention provides a preparation method of a hair nourishing composition, which is simple in process, fully retains effective components in raw materials, is simple and easy to implement, and is suitable for industrial large-scale production.
3. The eyelash peptide added in the invention activates keratin genes of eyelash follicles, promotes the absorption of nutrient components of eyelash follicles, and thus promotes the growth of eyelashes.
Detailed Description
The following examples are presented to assist those skilled in the art in a more complete understanding of the present invention, and are not intended to be limiting.
Example 1
An eyelash growth liquid comprises the following components in parts by weight: 60 parts of water, 0.5 part of hydrolyzed silk, 1 part of eyelash peptide, 1 part of carnosine, 1 part of pseudo-ginseng extract, 1 part of poria cocos extract, 1 part of fructus cnidii extract, 1 part of salvia miltiorrhiza extract, 0.1 part of polyethylene glycol 90M, 5 parts of propylene glycol, 0.05 part of caprylyl hydroximic acid and 0.05 part of 1, 2-hexanediol.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring water, polyethylene glycol 90M and propylene glycol for 20min, and heating to 80 deg.C to obtain emulsion A;
(2) adding hydrolyzed silk, eyelash peptide and carnosine and stirring for 10min when the temperature is reduced to 42 deg.C;
(3) cooling to 38 deg.C, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract, octanoyl hydroximic acid and 1, 2-hexanediol, stirring for 15min, discharging, aging for 10min, and inspecting to obtain eyelash growth liquid.
Example 2
An eyelash growth liquid comprises the following components in parts by weight: 90 parts of water, 1 part of hydrolyzed silk, 5 parts of eyelash peptide, 5 parts of carnosine, 5 parts of pseudo-ginseng extract, 5 parts of poria cocos extract, 5 parts of fructus cnidii extract, 5 parts of salvia miltiorrhiza extract, 0.8 part of polyethylene glycol 90M, 15 parts of propylene glycol, 0.5 part of caprylyl hydroximic acid and 0.5 part of 1, 2-hexanediol.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring water, polyethylene glycol 90M and propylene glycol for 20min, and heating to 80 deg.C to obtain emulsion A;
(2) adding hydrolyzed silk, eyelash peptide and carnosine and stirring for 10min when the temperature is reduced to 42 deg.C;
(3) cooling to 38 deg.C, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract, octanoyl hydroximic acid and 1, 2-hexanediol, stirring for 15min, discharging, aging for 10min, and inspecting to obtain eyelash growth liquid.
Example 3
An eyelash growth liquid comprises the following components in parts by weight: 70 parts of water, 0.5 part of hydrolyzed silk, 3 parts of eyelash peptide, 2 parts of carnosine, 2 parts of pseudo-ginseng extract, 2 parts of poria cocos extract, 2 parts of fructus cnidii extract, 2 parts of salvia miltiorrhiza extract, 0.2 part of polyethylene glycol 90M, 8 parts of propylene glycol, 0.05 part of caprylyl hydroximic acid and 0.05 part of 1, 2-hexanediol.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring water, polyethylene glycol 90M and propylene glycol for 20min, and heating to 80 deg.C to obtain emulsion A;
(2) adding hydrolyzed silk, eyelash peptide and carnosine and stirring for 10min when the temperature is reduced to 42 deg.C;
(3) cooling to 38 deg.C, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract, octanoyl hydroximic acid and 1, 2-hexanediol, stirring for 15min, discharging, aging for 10min, and inspecting to obtain eyelash growth liquid.
Example 4
An eyelash growth liquid comprises the following components in parts by weight: 80 parts of water, 1 part of hydrolyzed silk, 5 parts of eyelash peptide, 3 parts of carnosine, 3 parts of pseudo-ginseng extract, 3 parts of poria cocos extract, 3 parts of fructus cnidii extract, 3 parts of salvia miltiorrhiza extract, 0.5 part of polyethylene glycol 90M, 12 parts of propylene glycol, 0.3 part of caprylyl hydroximic acid and 0.2 part of 1, 2-hexanediol.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring water, polyethylene glycol 90M and propylene glycol for 20min, and heating to 80 deg.C to obtain emulsion A;
(2) adding hydrolyzed silk, eyelash peptide and carnosine and stirring for 10min when the temperature is reduced to 42 deg.C;
(3) cooling to 38 deg.C, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract, octanoyl hydroximic acid and 1, 2-hexanediol, stirring for 15min, discharging, aging for 10min, and inspecting to obtain eyelash growth liquid.
Example 5
An eyelash growth liquid comprises the following components in parts by weight: 71.5 parts of water, 1 part of hydrolyzed silk, 5 parts of eyelash peptide, 3 parts of carnosine, 2 parts of pseudo-ginseng extract, 2 parts of poria cocos extract, 2 parts of fructus cnidii extract, 3 parts of salvia miltiorrhiza extract, 0.5 part of polyethylene glycol 90M, 10 parts of propylene glycol, 0.1 part of caprylyl hydroximic acid and 0.1 part of 1, 2-hexanediol.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring water, polyethylene glycol 90M and propylene glycol for 20min, and heating to 80 deg.C to obtain emulsion A;
(2) adding hydrolyzed silk, eyelash peptide and carnosine and stirring for 10min when the temperature is reduced to 42 deg.C;
(3) cooling to 38 deg.C, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract, octanoyl hydroximic acid and 1, 2-hexanediol, stirring for 15min, discharging, aging for 10min, and inspecting to obtain eyelash growth liquid.
Comparative example 1
An eyelash growth liquid comprises the following components in parts by weight: 71.5 parts of water, 1 part of hydrolyzed silk, 3 parts of carnosine, 2 parts of a pseudo-ginseng extract, 2 parts of a poria cocos extract, 2 parts of a fructus cnidii extract, 3 parts of a salvia miltiorrhiza extract, 0.5 part of polyethylene glycol 90M, 10 parts of propylene glycol, 0.1 part of caprylyl hydroximic acid and 0.1 part of 1, 2-hexanediol.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring water, polyethylene glycol 90M and propylene glycol for 20min, and heating to 80 deg.C to obtain emulsion A;
(2) adding hydrolyzed silk, eyelash peptide and carnosine and stirring for 10min when the temperature is reduced to 42 deg.C;
(3) cooling to 38 deg.C, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract, octanoyl hydroximic acid and 1, 2-hexanediol, stirring for 15min, discharging, aging for 10min, and inspecting to obtain eyelash growth liquid.
Comparative example 2
An eyelash growth liquid comprises the following components in parts by weight: 71.5 parts of water, 1 part of hydrolyzed silk, 5 parts of eyelash peptide, 2 parts of pseudo-ginseng extract, 2 parts of poria cocos extract, 2 parts of fructus cnidii extract, 3 parts of salvia miltiorrhiza extract, 0.5 part of polyethylene glycol 90M, 10 parts of propylene glycol, 0.1 part of caprylyl hydroximic acid and 0.1 part of 1, 2-hexanediol.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring water, polyethylene glycol 90M and propylene glycol for 20min, and heating to 80 deg.C to obtain emulsion A;
(2) adding hydrolyzed silk, eyelash peptide and carnosine and stirring for 10min when the temperature is reduced to 42 deg.C;
(3) cooling to 38 deg.C, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract, octanoyl hydroximic acid and 1, 2-hexanediol, stirring for 15min, discharging, aging for 10min, and inspecting to obtain eyelash growth liquid.
Comparative example 3
An eyelash growth liquid comprises the following components in parts by weight: 71.5 parts of water, 5 parts of eyelash peptide, 3 parts of carnosine, 2 parts of pseudo-ginseng extract, 2 parts of poria cocos extract, 2 parts of fructus cnidii extract, 3 parts of salvia miltiorrhiza extract, 0.5 part of polyethylene glycol 90M, 10 parts of propylene glycol, 0.1 part of caprylyl hydroximic acid and 0.1 part of 1, 2-hexanediol.
A preparation method of eyelash growth liquid comprises the following steps:
(1) stirring water, polyethylene glycol 90M and propylene glycol for 20min, and heating to 80 deg.C to obtain emulsion A;
(2) adding hydrolyzed silk, eyelash peptide and carnosine and stirring for 10min when the temperature is reduced to 42 deg.C;
(3) cooling to 38 deg.C, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract, octanoyl hydroximic acid and 1, 2-hexanediol, stirring for 15min, discharging, aging for 10min, and inspecting to obtain eyelash growth liquid.
Eyelash grower use effect experiment:
180 volunteers aged 18-55 were recruited into 9 groups of 20 subjects each informed of the entire study and signed informed consent. Eight groups of subjects applied the eyelash growers prepared in examples 1 to 5 and comparative examples 1 to 3 (the first group was applied with the eyelash grower of example 1, the second group was applied with the eyelash grower of example 2, and so on, and the seventh group was applied with the eyelash grower of comparative example 3) every night, respectively, continuously for 1 month, during which no other product was used, normally moved, and the remaining group was used as a blank group and applied with deionized water using the same method. The effect of the use before and after 1 month of use is shown in table 1.
TABLE 1 eyelash grower using results prepared in examples 1 to 5 and comparative examples 1 to 3
Claims (9)
1. The eyelash growth liquid is characterized by comprising the following components in parts by weight: 60-90 parts of water, 0.5-1 part of hydrolyzed silk, 1-5 parts of eyelash peptide, 1-5 parts of carnosine, 4-20 parts of plant extract and 0.1-0.8 part of polyethylene glycol 90M; the plant extract comprises the following components in parts by weight: 1-5 parts of pseudo-ginseng extract, 1-5 parts of poria cocos extract, 1-5 parts of fructus cnidii extract and 1-5 parts of salvia miltiorrhiza extract; the notoginseng extract: the saponin contains ginsenoside Rb1, Rg1, Rg2, and ginsenoside Ra, Rb2, Rb and Re; the tuckahoe extract liquid comprises the following components: the effective component is pachyman; the fructus cnidii extracting solution: fructus Cnidii extract is extracted from fruit of fructus Cnidii of Umbelliferae, and contains pinene, isovalerian borneol ester, parsley methyl ether, dihydrocarveol, bergapten, osthole, and isoanisic apigenin; the red sage root extract: the main components are as follows: tanshinone IIA, salvianolic acid B, cryptotanshinone.
2. An eyelash grower according to claim 1, further comprising the following components in parts by weight: 5-15 parts of propylene glycol and 0.1-1 part of preservative.
3. Eyelash grower according to claim 2, characterized by comprising the following components in parts by weight: 70-80 parts of water, 0.5-1 part of hydrolyzed silk, 3-5 parts of eyelash peptide, 2-3 parts of carnosine, 2-3 parts of pseudo-ginseng extract, 2-3 parts of poria cocos extract, 2-3 parts of fructus cnidii extract, 2-3 parts of salvia miltiorrhiza extract, 0.2-0.5 part of polyethylene glycol 90M, 8-12 parts of propylene glycol and 0.1-0.5 part of preservative.
4. Eyelash grower according to claim 1, wherein the water is deuterium-depleted water having a D/H ratio of 30-50 ppm.
5. Eyelash grower according to any one of claims 2 to 3, wherein the preservative is one or more selected from the group consisting of caprylhydroxamic acid, 1, 2-hexanediol, p-hydroxyacetophenone, and 1, 2-pentanediol.
6. A method for preparing eyelash grower according to any one of claims 1 to 5, comprising the steps of:
(1) stirring and heating water, polyethylene glycol 90M and propylene glycol to obtain an emulsion A;
(2) cooling, adding hydrolyzed silk, eyelash peptide and carnosine, and stirring;
(3) continuously cooling, adding Notoginseng radix extract, Poria extract, fructus Cnidii extract, Saviae Miltiorrhizae radix extract and antiseptic, stirring, discharging, and aging to obtain eyelash growth liquid.
7. The method according to claim 6, wherein in the step (1), the stirring time is 10 to 20min, and the mixture is heated to 80 to 85 ℃.
8. The preparation method according to claim 6, wherein in the step (2), when the temperature is reduced to 40-45 ℃, hydrolyzed silk, eyelash peptide and carnosine are added; the stirring time is 10-20 min.
9. The preparation method according to claim 6, wherein in the step (3), the temperature is continuously reduced to 36-39 ℃, the stirring time is 10-15min, and the aging time is 15-30 min.
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CN110051555A (en) * | 2019-06-05 | 2019-07-26 | 南京迪维奥医药科技有限公司 | A kind of myristoyl pentapeptide -17 of generating hair and the composition of Wild soybean isoflavones |
CN110507594B (en) * | 2019-09-17 | 2022-06-17 | 上海百雀羚生物科技有限公司 | Toning lotion and preparation method thereof |
CN112842932A (en) * | 2021-03-31 | 2021-05-28 | 磐升瑞祥(山东)生物工程有限公司 | Essence for promoting eyelash growth and preparation method thereof |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009148551A1 (en) * | 2008-05-30 | 2009-12-10 | Jan Marini Skin Research | Cosmetic compositions |
WO2012145609A1 (en) * | 2011-04-21 | 2012-10-26 | Sunny Biodiscovery, Inc. | Transoral methods and compositions for wrinkle reduction and cosmetic lip and facial augmentation |
WO2014120793A1 (en) * | 2013-01-30 | 2014-08-07 | The Beauty Cartel, Llc. | Hair loss treatment compositions and methods of making and using same |
CN106214509A (en) * | 2016-08-24 | 2016-12-14 | 上海波林丝生物科技有限公司 | A kind of compositions promoting eyelashes to grow |
WO2017032711A1 (en) * | 2015-08-21 | 2017-03-02 | Gratia Mundi Gmbh | Active combinations, compositions and methods for enhancing hair growth |
CN106924069A (en) * | 2017-04-17 | 2017-07-07 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of eyelashes growth-promoting media containing polypeptide |
CN107569399A (en) * | 2017-10-19 | 2018-01-12 | 佛山娇芙生物科技有限公司 | A kind of mascara with the effect of dense eyelashes and preparation method thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20160000858A1 (en) * | 2014-07-07 | 2016-01-07 | Gojo Industries, Inc. | Compositions and methods for mitigating skin irritation and enhancing skin barrier function |
CN105232358B (en) * | 2015-10-29 | 2018-01-30 | 中山卡丝生物科技有限公司 | Compound for promoting eyelash growth and preparation method thereof |
CN105997735B (en) * | 2016-07-13 | 2019-08-06 | 奥俐莱雅(广东)家化科技有限公司 | A kind of natural hair-washing hair-care articles and its preparation method and application |
CN106726668A (en) * | 2016-11-19 | 2017-05-31 | 诺斯贝尔化妆品股份有限公司 | A kind of many peptidoliposome raw materials used in cosmetics |
CN107280994A (en) * | 2017-05-04 | 2017-10-24 | 上海章华保健化妆品有限公司 | One kind hydrolysis fibroin hair conditioner and preparation method thereof |
CN107929169A (en) * | 2017-12-28 | 2018-04-20 | 广东医科大学 | Deep layer skin-active elite stoste and preparation method thereof |
CN109700687B (en) * | 2018-02-13 | 2022-04-15 | 深圳高尚科美生物科技有限公司 | Flexible liposome cosmetic containing active polypeptide and preparation method thereof |
-
2018
- 2018-12-29 CN CN201811641381.6A patent/CN109512744B/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009148551A1 (en) * | 2008-05-30 | 2009-12-10 | Jan Marini Skin Research | Cosmetic compositions |
WO2012145609A1 (en) * | 2011-04-21 | 2012-10-26 | Sunny Biodiscovery, Inc. | Transoral methods and compositions for wrinkle reduction and cosmetic lip and facial augmentation |
WO2014120793A1 (en) * | 2013-01-30 | 2014-08-07 | The Beauty Cartel, Llc. | Hair loss treatment compositions and methods of making and using same |
WO2017032711A1 (en) * | 2015-08-21 | 2017-03-02 | Gratia Mundi Gmbh | Active combinations, compositions and methods for enhancing hair growth |
CN106214509A (en) * | 2016-08-24 | 2016-12-14 | 上海波林丝生物科技有限公司 | A kind of compositions promoting eyelashes to grow |
CN106924069A (en) * | 2017-04-17 | 2017-07-07 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of eyelashes growth-promoting media containing polypeptide |
CN107569399A (en) * | 2017-10-19 | 2018-01-12 | 佛山娇芙生物科技有限公司 | A kind of mascara with the effect of dense eyelashes and preparation method thereof |
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