CN108653144A - A kind of skin-lightening cosmetic - Google Patents
A kind of skin-lightening cosmetic Download PDFInfo
- Publication number
- CN108653144A CN108653144A CN201810759731.2A CN201810759731A CN108653144A CN 108653144 A CN108653144 A CN 108653144A CN 201810759731 A CN201810759731 A CN 201810759731A CN 108653144 A CN108653144 A CN 108653144A
- Authority
- CN
- China
- Prior art keywords
- parts
- skin
- lacquer tree
- extract
- flower extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of skin-lightening cosmetics.The present invention is using various plants extract as raw material, wherein containing bletilla striata extract, fiery sesame oil, lacquer tree oil, notoginseng haulm saponin(e, lacquer tree flower extract, pseudo-ginseng flower extract.It counts, is made of the following raw material in parts by weight：5~10 parts of bletilla striata extract, fiery 5~10 parts of sesame oil, 5~10 parts of lacquer tree oil, 5~10 parts of notoginseng haulm saponin(e, 5~10 parts of lacquer tree flower extract, 5~10 parts of pseudo-ginseng flower extract, 10~20 parts of other compositions, 20~60 parts of deionized water.The skin-lightening cosmetic of the present invention, is mainly made by crude vegetal and plant extracts, green, safety, non-stimulated to skin；The composition can be used in whitening formula, have effects that whitening, moisturizing, antibacterial anti-inflammatory to skin.
Description
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of skin-lightening cosmetic.
Background technology
It is everyone person's character to pursue beautiful appearance, and the state of skin and appearance are wherein important composition portions
Part, healthy and pale skin is that everybody is pursued.For this purpose, the demand to skin-lightening cosmetic occupies always various cosmetics demands
First of.
Skin histology is the first layer protective barrier of people, and broad sense can be divided into epidermis, corium and subcutaneous tissue.The face of skin
Color is mainly determined according to quantity, size and distribution containing melanin in Skin Cell.
The problem of for skin-whitening, depends primarily on the ability of melanocyte synthesis of melanin.In the epidermis base of people
Bottom iuntercellular, is dispersed with melanocyte, and the tyrosinase that it contains can be by oxidizing tyrosine at polysaccharide, and tyrosinase is
A kind of polyphenol enzyme, belongs to redox enzymes, and centre can finally generate melanin using a series of metabolic process.
Melanin production is more, and skin is pitch-darker；Conversely, then skin is more pale.Tyrosinase has unique dual catalytic work(
Can, it is the key enzyme of B16 cell in organism, the aging with people has substantial connection.Its abnormal overexpression can lead to human body
Pigmentation disease.Tyrosinase inhibitor can treat common chromatodermatosis such as freckle, yellowish-brown at present
Spot, senile plaque.So the ursin in popular skin-lightening cosmetic, vitamin C derivatives, kojic acid and its spreading out currently on the market
Chinese medical extracts such as biology, green-tea extract, licorice etc. are tyrosinase inhibitor, mainly by inhibiting junket ammonia
The activity of sour enzyme and reach inhibition B16 cell, and then play skin whitening effect.
In a kind of lightening compositions of patent CN201010214873.4, a kind of lightening compositions, the composition are disclosed
Contain mulberry bark extract, camomile extract, gadol extract, grape seed extract, licorice, the extraction of chicken mulberry
Object, ursin, kojic dipalmitate, niacinamide, tetrahydro curcumin, moisturizer and preservative, effective whitening in the invention
Ingredient can inhibit the activity of tyrosinase, block melanin transport, inhibit melanin to be formed, can be used for skin-lightening cosmetic
In, safely and effectively.
In a kind of whitening plant extract combinations of patent CN201310210916.5 and its application in cosmetics
In, disclose a kind of plant composition with whitening function and its application in skin-lightening cosmetic, the plant group of the invention
Object is closed by mulberry bark extract, licorice, peony extract, Flos Bombacis Malabarici extract, angelica extract, Cortex Moutan extract
It compounds.The plant composition of the invention can be used in whitening formula, have inhibit tyrosinase activity, remove free radical and
The function of skin whitening.
In a kind of skin-lightening cosmetics of patent CN201210511695.0 and preparation method thereof, a kind of whitening is disclosed
Cosmetic, the composition by weight percentage, are made of the following raw material：50~70wt% cucumber seeds oil, 15~25wt% St. John's
Careless oil, 15~25wt% pot marigold oils, preparation method are：50~70wt% cucumber seeds is oily, 15~25wt% St. john's worts oil,
15~25wt% pot marigold oils are mixed at a temperature of 20~25 DEG C, are stirred evenly to get product；The skin-lightening cosmetic of the invention, by
Crude vegetal is made, green, safety, non-stimulated to skin.
For skin-lightening cosmetic, China has abundant plant resources, modern biotechnology can be made full use of to extract
Active constituent in animals and plants, the research of comprehensive lightening mechanism, then scientific compatibility, bring out the best in each other, can obtain various naturalization
Cosmetic, to achieve the effect that skin whitening, this is to the abundant of China's whitening cosmetic product and China's cosmetic industry is pushed all to have
There is important realistic meaning.
In patented method of the present invention, by bletilla striata extract, fiery sesame oil, lacquer tree oil, notoginseng haulm saponin(e, lacquer tree
The plant extracts reflex such as flower extract, pseudo-ginseng flower extract, which is matched, prepares skin-lightening cosmetic at the national level by document and patent
Retrieval, has no and has been reported that.
Existing skin-lightening cosmetic is primarily present problems with and defect：
（1）There is the irritation to skin in part skin-lightening cosmetic, because often containing acid, alkali, salt, surface work in skin-lightening cosmetic
The chemically ingredient such as property agent.These chemical substances act on after mucous membrane of skin, organ etc. through often causing irritant skin sick
Become, also known as irritation contacts dermatitis, is a kind of most commonly seen skin lesion and local skin caused by skin-lightening cosmetic
The acute inflammation occurred rapidly.In addition, the group branch also in the whitening product of part is deposited in body, can not excrete out,
It can lead to that blood is unsmooth, aging phenomenon of skin, generate dark sore, color spot, skin sallow, wrinkle increase, relaxation, skin new old generation
It thanks and slows down.It can even be entered by placenta in fetus body, endanger the development of fetal central nervous system, cause harmful effect.
（2）Product stability is low, many anti-oxidant chemical efficiency ingredients of skin-lightening cosmetic, all carries one or several insatiable hungers
And double bond, these functional components because its stronger reproducibility can play the effect of inhibition melanin in skin, but are being made
When cosmetics finished product, then because its exposure in air more than the moon even a couple of days, just under the action ofs oxygen, light, metal ion etc. not
Saturated bond deactivation, loses whitening active, to keep whitening effect poor.
（3）Whitening approach is single, and melanin is generated by the chemical reaction of a series of complex, can have a plurality of approach to press down
Make its generation.And the whitening product overwhelming majority on Cosmetic Market is and every only based on tyrosinase inhibitor at present
Year finds such new compound with faster speed.But various whitening additives can only all inhibit an approach, and fail complete
Play the role of to face inhibiting melanin.
（4）Existing whitening cosmetic product is to embody effect, intentionally adds a variety of chemical compositions and uses hormone, though to skin
Skin has tender white effect, it is possible to reduce wrinkle, but some Management of Cosmetics Enterprises can add taboo regulated substance in its product（Such as antibiotic
Class）.These contain hormone cosmetics be used for a long time after, can make skin to hormone generate rely in addition systemic damage, one
Denier, which deactivates, there is also the reaction of the hormonal dependents scytitis such as pigmentations such as erythema, papule, exudation, telangiectasis.
According to above-mentioned deficiency, patent of the present invention is mainly improved optimization from the following aspect：
（1）Using pure natural on-chemically modified or synthesis composition.Under the premise of ensureing that product has preferable white-skinned face function as possible
The application to these compounds is reduced, the appearance for causing the above problem can be significantly improved.
（2）The composition for generating stimulation to skin is not added, and ensures that its safety exists for part whitening active ingredients
Stimulation sex chromosome mosaicism, can in prescription pure natural, mild, the neutral plant extracts of more additions, so that product is being reached whitening work(
While effect, irritation reduces, and is really achieved the purpose of safe whitening.
（3）Different approaches are combined, whitening active ingredients are carried out scientific composition by comprehensive skin whitening, multi-pronged, from
Different approaches inhibit melanogenesis, are finally reached the purpose of comprehensive whitening.
（4）Compound sexual function, by cosmetics made of Formulation Ingredients and preparation method of the invention, major function is U.S.
In vain, in addition also have effects that moisturizing is crease-resistant and antibacterial anti-inflammatory.
Invention content
The purpose of the present invention is by using Yunnan local characteristic, some living resources extracts are a kind of to human body to obtain
No skin irritation, whitening effect be good, functional, safe skin-lightening cosmetic, which is with various plants group
Conjunction object is primary raw material, mainly contains bletilla striata extract, fiery sesame oil, lacquer tree oil, notoginseng haulm saponin(e, lacquer tree flower extract, three
Seven flower extracts.It counts, is made of the following raw material in parts by weight：5~10 parts of bletilla striata extract, fiery 5~10 parts of sesame oil, lacquer tree oil
5~10 parts, 5~10 parts of notoginseng haulm saponin(e, 5~10 parts of lacquer tree flower extract, 5~10 parts of pseudo-ginseng flower extract, other compositions
10~20 parts, 20~60 parts of deionized water.
Also contain other auxiliary materials in the present composition, other compositions are hemicellulose, glycerine, 1,3-PD, thoroughly
Bright matter acid sodium, carbomer, triethanolamine, allantoin, nano-titanium dioxide, corn peptide liquid, antiseptic, glutathione, emulsifier.
Heretofore described lacquer tree flower extract is by after a certain amount of fresh lacquer tree drying and crushing, with ethyl alcohol, methanol
Or acetone reflux extracts crushed material, extracting solution is made after being concentrated and dried, and the mass percent concentration of ethyl alcohol, methanol or acetone is
40~70%.
Heretofore described pseudo-ginseng flower extract is by after a certain amount of fresh sanchi flower drying and crushing, with ethyl alcohol, methanol
Or acetone reflux extracts crushed material, extracting solution is made after being concentrated and dried, and the mass percent concentration of ethyl alcohol, methanol or acetone is
20~40%.
Heretofore described lacquer tree oil is lacquer tree seed nucleolus oil.
Heretofore described hemicellulose, glycerine, 1,3- propylene glycol, Sodium Hyaluronate, carbomer, triethanolamine, urine
Bursin, nano-titanium dioxide, corn peptide liquid, antiseptic, glutathione, emulsifier are conventional commercial product.
The advantages of the method for the present invention and technique effect：
1, the product that obtains makes the bletilla striata, fiery fiber crops, lacquer tree seed, notoginseng haulm, lacquer tree, sanchi flower and hemicellulose etc. in the present invention
Plant extracts obtains high value added utilization, is a kind of natural whiting cosmetics.
2, heretofore described cosmetics and preparation method thereof are with technique is relatively simple, cost is relatively low, compound emulsion
Feature with obvious effects afterwards, safety is good.
3, the formula cosmetics can be used as the whitening products such as lotion, essence, lotion through different concocting methods.
Invention is further described in detail below by embodiment for specific implementation mode, but the scope of the present invention is not
It is confined to the content, the method used unless otherwise specified in embodiment is conventional method, and the reagent used is such as without special
Explanation is conventional commercial reagent.
Specific implementation mode
Embodiment 1
This skin-lightening cosmetic constituent is counted in parts by weight, is made of the following raw material：5 parts of bletilla striata extract, fiery 5 parts of sesame oil, paint
5 parts of tree oil, 5 parts of notoginseng haulm saponin(e, 5 parts of lacquer tree flower extract, 5 parts of pseudo-ginseng flower extract, 10 parts of other compositions, deionized water
60 parts.Other compositions are by 0.5 part of hemicellulose, 2 parts of glycerine, 1 part of 1,3- propylene glycol, 0.2 part of Sodium Hyaluronate, carbomer 0.1
Part, 0.1 part of triethanolamine, 0.1 part of allantoin, 0.1 part of nano-titanium dioxide, 0.5 part of corn peptide liquid, antiseptic（Phenoxyethanol）
0.1 part, 0.3 part of glutathione, emulsifier（Wheat emulsifying wax）5 parts.
The preparation method of the said goods is as follows：
（1）Glycerine, 1,3-PD, stirring are added after Sodium Hyaluronate, allantoin, glutathione and corn peptide liquid are mixed
Mixing is for use；
（2）By fiery sesame oil, lacquer tree oil and emulsifier（Wheat emulsifying wax）Low whipping speed 50r/min, the condition that temperature is 70 DEG C
Under, it stirs evenly for use；
（3）Hemicellulose, nano-titanium dioxide are added to the container, then press solid-to-liquid ratio 1：25 are added water, and being again heated to temperature is
70 DEG C, under conditions of mixing speed 50r/min, time 10min, stirring is for use to being completely dissolved；
（4）Carbomer, triethanolamine are taken, presses solid-to-liquid ratio 1 in water：60 water suctions are impregnated, and homogeneous gel is stirred into；
（5）By step 1）, step 2）, step 3）With step 4）It is stirred evenly after mixing；
（6）In step 5）Bletilla striata extract, notoginseng haulm saponin(e, lacquer tree flower extract, Radix Notoginseng are added in the mixture of middle acquisition
Flower extract, antiseptic（Phenoxyethanol）, then surplus water is added, it is uniformly mixed；
（7）By step 6）The mixture of middle acquisition is pumped into homogenizer, is vacuumized and is in -0.04MPa, stirring, homogenizer rotating speed
1000r/min, homogeneous 5min；
（8）To step 7）The homogeneous mixture of middle acquisition carries out closed ageing, digestion time 12h, after the completion of ageing at normal temperatures
It can be obtained a kind of whitening and moistening skin lotion.
The index of correlation after using the present embodiment method is measured using common detection methods, wherein tyrosine enzyme activity
Property assay method use Mushroom tyrosinase DOPA rate oxidizing process, respectively with spectrophotometry measure superoxide anion from
By the scavenging effect of base and to Hydroxyl Radical Scavenging, specific targets data are as follows：
| Experimental project | Tyrosinase vigor inhibits | Scavenging effect to ultra-oxygen anion free radical | To hydroxyl radical free radical scavenging effect |
| Inhibiting rate（%） | 85.8 | 34.6 | 53.2 |
In addition, to its PFA value（Sun care preparations long wave ultraviolet protection index）And spf value（Sun protection factor）It is measured,
PFA values and spf value are respectively PFA values 7, SPF15.
Testing result shows that the activity of the enough effective inhibition tyrosinases of the whitening moisturizing lotion liquid energy is used for a long time and removes certainly
By the effect of base, effectively slow down the aggregate velocity of melanin, the absorption and antitan agent to ultraviolet light have good effect, together
When also have the function of moisturizing, moisturizing, skin care and brilliant white, and there is safety and nonirritant to human skin.
Embodiment 2
This skin-lightening cosmetic constituent is counted in parts by weight, is made of the following raw material：10 parts of bletilla striata extract, fiery 10 parts of sesame oil,
10 parts of lacquer tree oil, 10 parts of lacquer tree flower extract, 10 parts of pseudo-ginseng flower extract, 20 parts of other compositions, is gone 10 parts of notoginseng haulm saponin(e
20 parts of ionized water.Other compositions are by 0.2 part of hemicellulose, 3 parts of glycerine, 1 part of 1,3- propylene glycol, 0.3 part of Sodium Hyaluronate, card wave
0.1 part of nurse, 0.1 part of triethanolamine, 0.2 part of allantoin, 0.2 part of nano-titanium dioxide, 2.5 parts of corn peptide liquid, antiseptic（Benzene oxygen
Ethyl alcohol）0.1 part, 0.3 part of glutathione, emulsifier（Tween 80）12 parts
The preparation method of the said goods is as follows：
（1）Glycerine, 1,3-PD, stirring are added after Sodium Hyaluronate, allantoin, glutathione and corn peptide liquid are mixed
Mixing is for use；
（2）By fiery sesame oil, lacquer tree oil and emulsifier（Tween 80）Under conditions of low whipping speed 50r/min, temperature are 80 DEG C,
It stirs evenly for use；
（3）Hemicellulose, nano-titanium dioxide are added to the container, then press solid-to-liquid ratio 1：30 are added water, and being again heated to temperature is
75 DEG C, under conditions of mixing speed 150r/min, time 5min, stirring is for use to being completely dissolved；
（4）Carbomer, triethanolamine are taken, presses solid-to-liquid ratio 1 in water：30 water suctions are impregnated, and homogeneous gel is stirred into；
（5）By step 1）, step 2）, step 3）With step 4）It is stirred evenly after mixing；
（6）In step 5）Bletilla striata extract, notoginseng haulm saponin(e, lacquer tree flower extract, Radix Notoginseng are added in the mixture of middle acquisition
Flower extract, antiseptic（Phenoxyethanol）, then surplus water is added, it is uniformly mixed；
（7）By step 6）The mixture of middle acquisition is pumped into homogenizer, is vacuumized and is in -0.04MPa, stirring, homogenizer rotating speed
2000r/min, homogeneous 5min；
（8）To step 7）The homogeneous mixture of middle acquisition carries out closed ageing at normal temperatures, digestion time for 24 hours, after the completion of ageing
It can be obtained a kind of skin whitener.
The index of correlation after using the present embodiment method is measured using common detection methods, wherein tyrosine enzyme activity
Property assay method use Mushroom tyrosinase DOPA rate oxidizing process, respectively with spectrophotometry measure superoxide anion from
By the scavenging effect of base and to Hydroxyl Radical Scavenging, specific targets data are as follows：
| Experimental project | Tyrosinase vigor inhibits | Scavenging effect to ultra-oxygen anion free radical | To hydroxyl radical free radical scavenging effect |
| Inhibiting rate（%） | 88.8 | 45.2 | 56.2 |
In addition, to its PFA value（Sun care preparations long wave ultraviolet protection index）And spf value（Sun protection factor）It is measured,
PFA values and spf value are respectively PFA values 8, SPF15.
Testing result shows that the skin whitener, which is used for a long time, can effectively inhibit the activity of tyrosinase and remove free radical
Effect, effectively slows down the aggregate velocity of melanin, and the absorption and antitan agent to ultraviolet light have good effect, while also having
There are moisturizing, moisturizing, skin care and brilliant white, and there is safety and nonirritant to human skin.
Embodiment 3
This skin-lightening cosmetic constituent is counted in parts by weight, is made of the following raw material：6 parts of bletilla striata extract, fiery 6 parts of sesame oil, paint
6 parts of tree oil, 5 parts of notoginseng haulm saponin(e, 5 parts of lacquer tree flower extract, 5 parts of pseudo-ginseng flower extract, 13 parts of other compositions, deionized water
54 parts.Other compositions are by 0.3 part of hemicellulose, 3 parts of glycerine, 1 part of 1,3- propylene glycol, 0.2 part of Sodium Hyaluronate, carbomer 0.1
Part, 0.1 part of triethanolamine, 0.1 part of allantoin, 0.1 part of nano-titanium dioxide, 0.5 part of corn peptide liquid, antiseptic（Phenoxyethanol）
0.1 part, 0.5 part of glutathione, emulsifier（Match Bick S305, olive emulsifying wax, mass ratio 1:1）6 parts
The preparation method of the said goods is as follows：
（1）Glycerine, 1,3-PD, stirring are added after Sodium Hyaluronate, allantoin, glutathione and corn peptide liquid are mixed
Mixing is for use；
（2）By fiery sesame oil, lacquer tree oil and emulsifier（Match Bick S305, olive emulsifying wax, mass ratio 1:1）Low whipping speed
Under conditions of 50r/min, temperature are 80 DEG C, stir evenly for use；
（3）Hemicellulose, nano-titanium dioxide are added to the container, then press solid-to-liquid ratio 1：50 are added water, and being again heated to temperature is
75 DEG C, under conditions of mixing speed 150r/min, time 5min, stirring is for use to being completely dissolved；
（4）Carbomer, triethanolamine are taken, presses solid-to-liquid ratio 1 in water：60 water suctions are impregnated, and homogeneous gel is stirred into；
（5）By step 1）, step 2）, step 3）With step 4）It is stirred evenly after mixing；
（6）In step 5）Bletilla striata extract, notoginseng haulm saponin(e, lacquer tree flower extract, Radix Notoginseng are added in the mixture of middle acquisition
Flower extract, antiseptic（Phenoxyethanol）, then surplus water is added, it is uniformly mixed；
（7）By step 6）The mixture of middle acquisition is pumped into homogenizer, is vacuumized and is in -0.04MPa, stirring, homogenizer rotating speed
2000r/min, homogeneous 5min；
（8）To step 7）The homogeneous mixture of middle acquisition carries out closed ageing at normal temperatures, digestion time for 24 hours, after the completion of ageing
It can be obtained a kind of body whitening crème.
The index of correlation after using the present embodiment method is measured using common detection methods, wherein tyrosine enzyme activity
Property assay method use Mushroom tyrosinase DOPA rate oxidizing process, respectively with spectrophotometry measure superoxide anion from
By the scavenging effect of base and to Hydroxyl Radical Scavenging, specific targets data are as follows：
| Experimental project | Tyrosinase vigor inhibits | Scavenging effect to ultra-oxygen anion free radical | To hydroxyl radical free radical scavenging effect |
| Inhibiting rate（%） | 82.4 | 33.2 | 54.1 |
In addition, to its PFA value（Sun care preparations long wave ultraviolet protection index）And spf value（Sun protection factor）It is measured,
PFA values and spf value are respectively PFA values 7, SPF15.
Testing result shows that the body whitening crème, which is used for a long time, can effectively inhibit the activity of tyrosinase and remove freely
The effect of base effectively slows down the aggregate velocity of melanin, and the absorption and antitan agent to ultraviolet light have good effect, simultaneously
Also have the function of whitening, moisturizing, moisturizing, moisturizing, antibacterial anti-inflammatory, and there is safety and nonirritant to human skin.
Embodiment 4
This skin-lightening cosmetic constituent is counted in parts by weight, is made of the following raw material：8 parts of bletilla striata extract, fiery 8 parts of sesame oil, paint
8 parts of tree oil, 7 parts of notoginseng haulm saponin(e, 7 parts of lacquer tree flower extract, 6 parts of pseudo-ginseng flower extract, 12 parts of other compositions, deionized water
44 parts.Other compositions are by 0.3 part of hemicellulose, 4.5 parts of glycerine, 2 parts of 1,3- propylene glycol, 0.2 part of Sodium Hyaluronate, allantoin
0.1 part, 0.1 part of nano-titanium dioxide, 0.5 part of corn peptide liquid, antiseptic（Phenoxyethanol）0.1 part, 0.2 part of glutathione, breast
Agent（Match Bick S305, olive emulsifying wax, mass ratio 1:1）4 parts.
The preparation method of the said goods is as follows：
（1）The mixing oil phase of glycerine, 1,3- propylene glycol will be added in Sodium Hyaluronate, allantoin, glutathione and corn peptide liquid
In, it stirs and evenly mixs for use；
（2）By fiery sesame oil, lacquer tree oil and emulsifier（Match Bick S305, olive emulsifying wax, mass ratio 1:1）Low whipping speed
Under conditions of 50r/min, temperature are 70 DEG C, stir evenly for use；
（3）Hemicellulose, nano-titanium dioxide are added to the container, then press solid-to-liquid ratio 1：35 are added water, and being again heated to temperature is
70 DEG C, under conditions of mixing speed 50r/min, time 10min, stirring is for use to being completely dissolved；
（4）By step 1）, step 2）With step 3）It is stirred evenly after mixing；
（5）In step 4）Bletilla striata extract, notoginseng haulm saponin(e, lacquer tree flower extract, Radix Notoginseng are added in the mixture of middle acquisition
Flower extract, antiseptic（Phenoxyethanol）, then surplus water is added, it is uniformly mixed；
（6）By step 5）The mixture of middle acquisition is pumped into homogenizer, is vacuumized after -0.04MPa, stirring, homogeneous 5min,
Matter machine rotating speed is 1000r/min；
（7）To step 6）The mixture of middle acquisition carries out closed ageing, digestion time 36h, after the completion of ageing at normal temperatures
Obtain a kind of skin whitener.
The index of correlation after using the present embodiment method is measured using common detection methods, wherein tyrosine enzyme activity
Property assay method use Mushroom tyrosinase DOPA rate oxidizing process, respectively with spectrophotometry measure superoxide anion from
By the scavenging effect of base and to Hydroxyl Radical Scavenging, specific targets data are as follows：
| Experimental project | Tyrosinase vigor inhibits | Scavenging effect to ultra-oxygen anion free radical | To hydroxyl radical free radical scavenging effect |
| Inhibiting rate（%） | 82.8 | 33.6 | 51.2 |
In addition, to its PFA value (sun care preparations long wave ultraviolet protection index) and spf value（Sun protection factor）It is measured,
PFA values and spf value are respectively PFA values 6, SPF15.
Testing result shows that the skin whitener, which is used for a long time, can effectively inhibit the activity of tyrosinase and remove free radical
Effect, effectively slows down the aggregate velocity of melanin, and the absorption and antitan agent to ultraviolet light have good effect, while also having
There are whitening, moisturizing, moisturizing, moisturizing, antibacterial anti-inflammatory, and there is safety and nonirritant to human skin.
Claims (6)
1. a kind of skin-lightening cosmetic, it is characterised in that contain bletilla striata extract, fiery sesame oil, lacquer tree oil, notoginseng haulm saponin(e, lacquer tree
Flower extract, pseudo-ginseng flower extract.
2. a kind of skin-lightening cosmetic according to claim 1, which is characterized in that count in parts by weight, by the following raw material system
At：5~10 parts of bletilla striata extract, fiery 5~10 parts of sesame oil, 5~10 parts of lacquer tree oil, 5~10 parts of notoginseng haulm saponin(e, lacquer tree carry
Take 5~10 parts of object, 5~10 parts of pseudo-ginseng flower extract, 10~20 parts of other compositions, 20~60 parts of deionized water.
3. according to a kind of skin-lightening cosmetic of claim 1 and 2, which is characterized in that the lacquer tree oil is lacquer tree seed nucleolus oil.
4. according to a kind of skin-lightening cosmetic of claim 1 and 2, which is characterized in that the lacquer tree flower extract is will be certain
After the fresh lacquer tree drying and crushing of amount, with alcoholic solution or ethyl acetate solution refluxing extraction crushed material, extracting solution is concentrated and dried
After be made, the mass percent concentration of alcoholic solution or ethyl acetate solution is 40~70%.
5. according to a kind of skin-lightening cosmetic of claim 1 and 2, which is characterized in that the pseudo-ginseng flower extract is will be certain
After the fresh sanchi flower drying and crushing of amount, with alcoholic solution or ethyl acetate solution refluxing extraction crushed material, extracting solution is concentrated and dried
After be made, the mass percent concentration of alcoholic solution or ethyl acetate solution is 20~40%.
6. a kind of skin-lightening cosmetic according to claim 2, which is characterized in that other compositions be hemicellulose, glycerine,
1,3- propylene glycol, Sodium Hyaluronate, carbomer, triethanolamine, allantoin, nano-titanium dioxide, corn peptide liquid, antiseptic, paddy
The sweet peptide of Guang, emulsifier.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810759731.2A CN108653144B (en) | 2018-07-11 | 2018-07-11 | Whitening cosmetic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810759731.2A CN108653144B (en) | 2018-07-11 | 2018-07-11 | Whitening cosmetic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108653144A true CN108653144A (en) | 2018-10-16 |
| CN108653144B CN108653144B (en) | 2021-02-09 |
Family
ID=63774036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810759731.2A Expired - Fee Related CN108653144B (en) | 2018-07-11 | 2018-07-11 | Whitening cosmetic |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108653144B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112608949A (en) * | 2020-12-18 | 2021-04-06 | 西南林业大学 | Preparation method and application of pseudo-ginseng flower extract |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302423A (en) * | 2011-08-26 | 2012-01-04 | 广州佳禾化妆品制造有限公司 | Micro-emulsion matrix for whitening cosmetics and preparation method for micro-emulsion matrix |
| KR20140060924A (en) * | 2012-11-13 | 2014-05-21 | 주식회사 나우코스 | Cosmetic composition of powder type |
| CN104027293A (en) * | 2014-06-27 | 2014-09-10 | 王忠良 | Whitening cosmetic and preparation method thereof |
| CN104147064A (en) * | 2014-08-15 | 2014-11-19 | 中国林业科学研究院林产化学工业研究所 | Lacquer tree polyphenol extract capable of inhibiting activity of tyrosinase and preparation method thereof |
| CN105769691A (en) * | 2016-04-07 | 2016-07-20 | 景东旭 | Herbal skin care product |
| CN107137295A (en) * | 2017-07-06 | 2017-09-08 | 王文军 | A kind of drug ingedient whitening spot-removing crease-resistant anti-aging composition and cosmetics |
-
2018
- 2018-07-11 CN CN201810759731.2A patent/CN108653144B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302423A (en) * | 2011-08-26 | 2012-01-04 | 广州佳禾化妆品制造有限公司 | Micro-emulsion matrix for whitening cosmetics and preparation method for micro-emulsion matrix |
| CN102302423B (en) * | 2011-08-26 | 2013-01-30 | 广东丸美生物技术股份有限公司 | Micro-emulsion matrix for whitening cosmetics and preparation method for micro-emulsion matrix |
| KR20140060924A (en) * | 2012-11-13 | 2014-05-21 | 주식회사 나우코스 | Cosmetic composition of powder type |
| CN104027293A (en) * | 2014-06-27 | 2014-09-10 | 王忠良 | Whitening cosmetic and preparation method thereof |
| CN104147064A (en) * | 2014-08-15 | 2014-11-19 | 中国林业科学研究院林产化学工业研究所 | Lacquer tree polyphenol extract capable of inhibiting activity of tyrosinase and preparation method thereof |
| CN105769691A (en) * | 2016-04-07 | 2016-07-20 | 景东旭 | Herbal skin care product |
| CN107137295A (en) * | 2017-07-06 | 2017-09-08 | 王文军 | A kind of drug ingedient whitening spot-removing crease-resistant anti-aging composition and cosmetics |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112608949A (en) * | 2020-12-18 | 2021-04-06 | 西南林业大学 | Preparation method and application of pseudo-ginseng flower extract |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108653144B (en) | 2021-02-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104027293B (en) | A kind of skin-lightening cosmetic and preparation method thereof | |
| CN105395467B (en) | A kind of Chinese medicine composition, skin beautifying cosmetic and its application | |
| CN105381007B (en) | External medicine composition, preparation with white-skinned face function and its preparation method and application | |
| CN112494406A (en) | Whitening and freckle-removing cosmetic and preparation method thereof | |
| CN103565730A (en) | Scented tea whitening skin-moistening cream and preparation method thereof | |
| CN110090191B (en) | After-sun repair composition and cosmetic thereof | |
| CN108524357A (en) | A kind of fresh and alive beautiful fine flour frost of the root extract containing Aplotaxis auriculata and preparation method thereof | |
| Thakre | Formulation and development of de pigment serum incorporating fruits extract | |
| CN100558340C (en) | Cucurbitaceae oil is used to suppress the active application of 5 | |
| KR101809266B1 (en) | Cosmetic composition containing propolis complex extracts | |
| CN105434239B (en) | A kind of application of skin lightening compositions containing natural botanical source in cosmetics | |
| CN113576933A (en) | Composition with whitening effect and preparation method and application thereof | |
| CN107157910A (en) | A kind of skin care compositions with dual moisture-keeping efficacy and preparation method and application | |
| CN109106677A (en) | A kind of composition and its application with whitening function | |
| KR100443588B1 (en) | Cosmetic composition containing paeonia suffruticosa andrews extract and albizzia julibrissin dura extract having anti-ageing effect | |
| CN111166707B (en) | Facial anti-aging repairing and nursing composition and preparation method and application thereof | |
| CN100588389C (en) | Chinese medicine combination with whitening function and uses thereof | |
| KR20140025239A (en) | Cosmetic composition containing active fractions of rubus coreanus miq root | |
| CN108653144A (en) | A kind of skin-lightening cosmetic | |
| WO2015010372A1 (en) | Cream used for treatment of acne hyperpigmentation spot and for whitening | |
| KR101139373B1 (en) | Cosmetic composition for skinwhitening and manufacturing method thereof and mask-pack containing this | |
| KR20150074537A (en) | Cosmetic composition containing Ocimum basilicum seed extract | |
| KR101402193B1 (en) | Cosmetic composition for skin whitening containig pleurotus ferulae fruit body extract or pleurotus ferulae mycelium extract or pleurotus ferulae mycelium culture fluid | |
| KR101458496B1 (en) | A skin-care agent for anti-inflammatory containig Pleurotus ferulae fruit body extract or Pleurotus ferulae mycelium extract or Pleurotus ferulae mycelium culture fluid | |
| KR101017586B1 (en) | Cosmetic composition for skin whitening |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20210115 Address after: Room 1401, building 1, No.2, Dagang Road, chebei, Tianhe District, Guangzhou, Guangdong 510630 Applicant after: Guangzhou xiangpulan e-commerce Co.,Ltd. Address before: 528415 floor 1-4 and top floor of building B, No.33, Shengping East Road, East District, Xiaolan Town, Zhongshan City, Guangdong Province Applicant before: ZHONGSHAN ZHILIAN BUSINESS INCUBATOR DEVELOPMENT Co.,Ltd. |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210209 |