CN102302423A - Micro-emulsion matrix for whitening cosmetics and preparation method for micro-emulsion matrix - Google Patents
Micro-emulsion matrix for whitening cosmetics and preparation method for micro-emulsion matrix Download PDFInfo
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Abstract
The invention discloses micro-emulsion matrix for whitening cosmetics and a preparation method for the micro-emulsion matrix. The micro-emulsion matrix for the whitening cosmetics is oil-in-water micro-emulsion using turmeric extract, blackberry lily extract and cherry plum extract as main active ingredients, and comprises the following components in part by weight: 3 to 7 parts of turmeric extract, 1 to 5 parts of blackberry lily extract, 2 to 8 parts of cherry plum extract, 10 to 36 parts of surfactant, 0.05 to 2 parts of vitamin E oil and 50 to 70 parts of distilled water. By reasonably optimizing the consumption of the turmeric extract, the blackberry lily extract and the cherry plum extract, the three substances are complementary, and all-around nursing on skin whitening is realized. The micro-emulsion matrix for the whitening cosmetics has the characteristics of high thermodynamic stability, good storage stability, good light transmission property, good corrosion resistance, higher diffusivity of the active ingredients, good skin permeability and whitening effect and the like; and when the micro-emulsion matrix is added into the conventional whitening cosmetics, the whitening effect of the whitening cosmetics can be effectively improved, so the micro-emulsion matrix has broad market.
Description
Technical field
The present invention relates to the cosmetics technical field, be specifically related to the skin-lightening cosmetic field, relate in particular to a kind of skin-lightening cosmetic with micro-emulsion stroma and preparation method thereof.
Background technology
Whitening is an extremely important research field of cosmetics; The Asia women never stops for the pursuit of light just as the mankind for the pursuit of whitening; All kinds of whitening and skin-protecting products generally occurs like rain the back spring bamboo; Wherein a lot of chemical whitening agents with synthetic are main component; Though the short time effect is obvious; But big to skin irritation, produce a lot of negative effects.
Along with the notion of green safety becomes more and more popular, Skin whitening care cosmetics safety and effect property become the focus that consumer and producer pay close attention to simultaneously.People have turned to sight the active substance of some natural extract; It extracts from natural material; Chemical constitution and biological activity do not change; And its have multi-efficiency, lasting medicine stable, widely applicable, have no side effect or side effect very little, be the development trend of back to nature, science skin protection.
Along with people melanin is generated the continuous understanding of biological mechanism in recent years; From natural product, seeking the active substance of whitening safely and effectively becomes the cosmetics research focus, therefore excavates more natural material active component to the skin Magnesium Ascorbylphosphate and has very high economic worth and vast market prospect.
Microemulsion is by spontaneous formation such as water, oil and surfactants, and particle diameter is that the thermodynamic power of 10～100nm is learned stabilising system.At cosmetic field, product is an emulsion mostly, and its particle diameter is generally all greater than 400nm.
Microemulsion has the advantages that as a kind of specific form of emulsion general emulsion can't have: as thermodynamic stability is high, light transmission is good, antiseptic property is good and effective ingredient has higher diffusibility and percutaneous permeability etc.
Research emphasis for microemulsion system is to select suitable surfactant, consider nontoxicly, green, non-stimulated etc., also will seek simultaneously and the corresponding to emulsification method of surfactant.
Summary of the invention
The objective of the invention is to existing deficiency; Providing a kind of is raw material with natural plant extracts (liquid); Get through the microemulsified prepared; Has fine whitening effect; And the skin-lightening cosmetic micro-emulsion stroma of green safety, this micro-emulsion stroma can make the performance of whitening of existing skin-lightening cosmetic be significantly improved.
Another object of the present invention provides the method for preparing of above-mentioned skin-lightening cosmetic with micro-emulsion stroma.
Above-mentioned purpose of the present invention is achieved through following scheme:
The inventor is to the present situation of present whitening product; Various plants is carried out extraction of active ingredients; And whether study its extract (liquid) to the effect of skin Pear Power; Through having discovered that three kind of plant extracts (liquid) have good whitening function to skin really; And each self-whitening principle is all different with approach; Therefore the inventor considers again this three kind of plant extract (liquid) is reasonably arranged in pairs or groups; Through optimizing its formula ratio; Make that three's white-skinned face function can be complementary, and reach best whitening effect.
A kind of skin-lightening cosmetic micro-emulsion stroma, this micro-emulsion stroma are to be the water oil-packaging type micro-emulsion of main active with Rhizoma Curcumae Longae extracting solution, Rhizoma Belamcandae extracting solution and mirabalan extracting solution, specifically comprise each component of following parts by weight:
3～7 parts of Rhizoma Curcumae Longae extracts;
1～5 part of Rhizoma Belamcandae extract;
2～8 parts of mirabalan extracts;
10～36 parts in surfactant;
0.05～2 part of vitamin E oil;
50～70 parts of distilled water.
Above-mentioned Rhizoma Curcumae Longae extract is after the Rhizoma Curcumae Longae rhizome is pulverized, with 75% alcohol reflux 3 times after, and merge extractive liquid,, 5 times obtain Rhizoma Curcumae Longae extract after concentrated; The inventor finds that through this Rhizoma Curcumae Longae extract being studied the back this Rhizoma Curcumae Longae extract can suppress the generation of dermal melanin, and has high oxidation resistance and whitening function, and healing that can also family members' skin scar reduces the formation of scar.
Above-mentioned Rhizoma Belamcandae extract is after Rhizoma Belamcandae is pulverized, behind 90% alcohol reflux 3 times, and merge extractive liquid,, five times obtain Rhizoma Belamcandae extract after concentrating; The inventor finds that through this Rhizoma Belamcandae extract being studied the back this Rhizoma Belamcandae extract has good anti-aging effects, and moisturizing is effective, and can soften skin surface.
Above-mentioned mirabalan extract is to adopt commercially available mirabalan extract (ClairIu liquid), like the hydrolysis mirabalan extract of Japanese firm's production; The mirabalan extract can effectively suppress keratinocyte to be engulfed melanic, reaches the effect of whitening thereby stop melanin to get into horny layer.
Above-mentioned surfactant is one or both compositionss in polyoxyethylene hydrogenated Oleum Ricini or the polyoxyethylene castor oil; In the composition of raw materials of skin-lightening cosmetic of the present invention with micro-emulsion stroma; Its main active is a Rhizoma Curcumae Longae extract; Rhizoma Belamcandae extract and mirabalan extract; Though these three kinds of extracts are to adopt the method for distilling of the special optimal design of the inventor to obtain; But wherein still be the composition more complicated; Finally obtain limpid transparent micro-emulsion stroma in order to do; So the inventor is through screening the exhibiting high surface activating agent; Finally obtain surfactant of the present invention; This surfactant has not only guaranteed microemulsified of the present invention, and has green; Nontoxic and non-stimulated characteristics.
Said vitamin E oil plays auxiliary defying age in composition of raw materials, increase the effect of nutrient for skin.
Above-mentioned skin-lightening cosmetic is with the method for preparing of micro-emulsion stroma, and its concrete steps are following:
According to the above-mentioned raw materials prescription; With Rhizoma Curcumae Longae extract; Rhizoma Belamcandae extract; The mirabalan extract; Vitamin E oil; Surfactant and water mix homogeneously; This moment, mixed system was also opaque; And some insoluble matter depositions are arranged; Heat and remain under 50 ℃ this moment; This mixed system is stirred at the uniform velocity (but manual stirring also can mechanical agitation; Like magnetic agitation etc.); After keeping a period of time, system occurs transparent, stops heating; Naturally be cooled to room temperature; This mixed system is still kept clear, again this mixed system is removed precipitated impurities through filtering to handle, and then prepares required skin-lightening cosmetic micro-emulsion stroma.
Compared with prior art, the present invention has following beneficial effect:
1. the present invention adopts Rhizoma Curcumae Longae extract, Rhizoma Belamcandae extract and mirabalan extract, and through its consumption of reasonably optimizing, it is complementary to make three kinds of materials realize, realizes the comprehensive nursing to skin-whitening;
2. Rhizoma Curcumae Longae extract of the present invention, Rhizoma Belamcandae extract and mirabalan extract; Its extraction process is the inventor and gropes the back through a large amount of experimental designs and data and optimize and to obtain; Not only can realize wherein effective separation of active component, and help the microemulsified technology in later stage;
3. microemulsified technology of the present invention is the characteristics to composition of raw materials of the present invention, and special optimal design, not only can keep the active component of extract effectively, and simple to operate, and microemulsified is effective;
4. skin-lightening cosmetic micro-emulsion stroma of the present invention; Warp is tested its thermodynamic stability height, excellent storage stability, light transmission is good, antiseptic property is good, effective ingredient has higher diffusibility, percutaneous permeability; And whitening effect is good; Add in the existing skin-lightening cosmetic and can improve its whitening effect effectively, have vast market.
The specific embodiment
Below in conjunction with specific embodiment the present invention is done description further, but specific embodiment is not done any qualification to the present invention.
Embodiment 1
The skin-lightening cosmetic micro-emulsion stroma of present embodiment, this micro-emulsion stroma are to be the water oil-packaging type micro-emulsion of main active with Rhizoma Curcumae Longae extracting solution, Rhizoma Belamcandae extracting solution and mirabalan extracting solution, specifically comprise each component of following parts by weight:
3.5 parts of Rhizoma Curcumae Longae extracts;
3 parts of Rhizoma Belamcandae extract;
6 parts of mirabalan extracts;
20 parts in surfactant;
0.05 part of vitamin E oil;
67 parts of distilled water.
Above-mentioned Rhizoma Curcumae Longae extract is after the Rhizoma Curcumae Longae rhizome is pulverized, with 75% alcohol reflux 3 times after, and merge extractive liquid,, 5 times obtain Rhizoma Curcumae Longae extract after concentrated.
Above-mentioned Rhizoma Belamcandae extract is after Rhizoma Belamcandae is pulverized, behind 90% alcohol reflux 3 times, and merge extractive liquid,, five times obtain Rhizoma Belamcandae extract after concentrating.
Above-mentioned mirabalan extract is to adopt commercially available mirabalan extract (ClairIu liquid).
Above-mentioned surfactant is a polyoxyethylene hydrogenated Oleum Ricini.
Said vitamin E oil is the commercially available prod.
Above-mentioned skin-lightening cosmetic is with the method for preparing of micro-emulsion stroma, and its concrete steps are following:
According to the above-mentioned raw materials prescription; With Rhizoma Curcumae Longae extract; Rhizoma Belamcandae extract; The mirabalan extract; Vitamin E oil; Surfactant and water mix homogeneously; This moment, mixed system was also opaque; And some insoluble matter depositions are arranged; Heat and remain under 50 ℃ this moment; This mixed system is at the uniform velocity stirred (magnetic agitation); After keeping a period of time; System occurs transparent; Stop heating, be cooled to room temperature naturally, this mixed system is still kept clear; Again this mixed system is removed precipitated impurities through filtering to handle, then prepare required skin-lightening cosmetic micro-emulsion stroma.
Embodiment 2
The skin-lightening cosmetic micro-emulsion stroma of present embodiment, this micro-emulsion stroma each amounts of components in composition of raw materials was as follows, all the other were with embodiment 1:
7 parts of Rhizoma Curcumae Longae extracts;
1.5 parts of Rhizoma Belamcandae extract;
2 parts of mirabalan extracts;
20 parts in surfactant;
1 part of vitamin E oil;
69 parts of distilled water.
The present embodiment skin-lightening cosmetic with the method for preparing of micro-emulsion stroma with embodiment 1.
Embodiment 3
The skin-lightening cosmetic micro-emulsion stroma of present embodiment, this micro-emulsion stroma each amounts of components in composition of raw materials was as follows, all the other were with embodiment 1:
4 parts of Rhizoma Curcumae Longae extracts;
1 part of Rhizoma Belamcandae extract;
8 parts of mirabalan extracts;
30 parts in surfactant;
2 parts of vitamin E oils;
55 parts of distilled water.
The present embodiment skin-lightening cosmetic with the method for preparing of micro-emulsion stroma with embodiment 1.
Embodiment 4
The skin-lightening cosmetic micro-emulsion stroma of present embodiment, this micro-emulsion stroma each amounts of components in composition of raw materials was as follows, all the other were with embodiment 1:
5 parts of Rhizoma Curcumae Longae extracts;
4 parts of Rhizoma Belamcandae extract;
3 parts of mirabalan extracts;
16 parts in surfactant;
2 parts of vitamin E oils;
70 parts of distilled water.
The present embodiment skin-lightening cosmetic with the method for preparing of micro-emulsion stroma with embodiment 1.
Embodiment 5 stability experiments
1, light stability experiment
The skin-lightening cosmetic of embodiment 1～4 is respectively charged in the vial with micro-emulsion stroma; Sealing places under the daylight, and light at room temperature was according to 15 days, and the result shows that the skin-lightening cosmetic of embodiment 1～4 all keeps the clear outward appearance with micro-emulsion stroma; Color does not change, phenomenons such as no layering.
2, temperature stability experiment
The skin-lightening cosmetic of embodiment 1 is loaded on respectively in several vials with micro-emulsion stroma, investigates three months as under 4 ℃, 25 ℃, 40 ℃ and 60 ℃ of four temperature after the sealing; In like manner also respectively the skin-lightening cosmetic of embodiment 2～4 is carried out identical experiment with micro-emulsion stroma.
At any time sampling is observed in the middle of 3 months, and the result is illustrated in skin-lightening cosmetic of the present invention under four temperature and all keeps the outward appearance of clear, no lamination with micro-emulsion stroma.
Embodiment 6 whitening effect evaluation experimentals
Estimate the whitening effect of embodiment 1～4 skin-lightening cosmetic through operational test with micro-emulsion stroma.The skin-lightening cosmetic that the skin-lightening cosmetic that the skin-lightening cosmetic that test is divided into embodiment 1 preparation prepares with micro-emulsion stroma, embodiment 3 with the skin-lightening cosmetic of micro-emulsion stroma, embodiment 2 preparations prepares with micro-emulsion stroma, embodiment 4 is with micro-emulsion stroma and do not add the product (comparable group) of skin-lightening cosmetic of the present invention with micro-emulsion stroma, totally five experimental grouies.
30～40 years old women are totally 50 depositions of utilizing the ultra-vioket radiation device to cause dermal melanin; They are divided into two groups arbitrarily; Every day, each touched an amount of above-mentioned five experimental grouies on the arm after washing for twice more sooner or later, continuous two months, detected by an unaided eye on arm, must improve and estimated whitening effect.The result shows as shown in table 1.
Table 1 whitening effect evaluation result
| ? | Effectively | Effective a little | Invalid | Effective percentage (%) |
| Embodiment 1 skin-lightening cosmetic micro-emulsion stroma | 40 | 7 | 3 | 94 |
| Embodiment 2 skin-lightening cosmetic micro-emulsion stromas | 42 | 6 | 2 | 96 |
| Embodiment 3 skin-lightening cosmetic micro-emulsion stromas | 40 | 8 | 2 | 96 |
| Embodiment 4 skin-lightening cosmetic micro-emulsion stromas | 43 | 4 | 3 | 94 |
| Do not add the product of skin-lightening cosmetic of the present invention with micro-emulsion stroma | 5 | 10 | 35 | 30 |
Can find out from result's contrast of table 1; Skin-lightening cosmetic of the present invention has the good skin whitening effect really with micro-emulsion stroma; And, in that being used with micro-emulsion stroma on the most of those who are investigated at skin, skin-lightening cosmetic of the present invention can not observe stimulation to skin.
Claims (4)
1. skin-lightening cosmetic micro-emulsion stroma is characterized in that it is with Rhizoma Curcumae Longae extracting solution, Rhizoma Belamcandae extracting solution and the mirabalan extracting solution water oil-packaging type micro-emulsion as main active that this skin-lightening cosmetic uses micro-emulsion stroma, specifically comprises each component of following parts by weight:
3～7 parts of Rhizoma Curcumae Longae extracts;
1～5 part of Rhizoma Belamcandae extract;
2～8 parts of mirabalan extracts;
10～36 parts in surfactant;
0.05～2 part of vitamin E oil;
50～70 parts of distilled water;
Above-mentioned Rhizoma Curcumae Longae extract is after the Rhizoma Curcumae Longae rhizome is pulverized, with 75% alcohol reflux 3 times after, and merge extractive liquid,, 5 times obtain Rhizoma Curcumae Longae extract after concentrated;
Above-mentioned Rhizoma Belamcandae extract is after Rhizoma Belamcandae is pulverized, behind 90% alcohol reflux 3 times, and merge extractive liquid,, five times obtain Rhizoma Belamcandae extract after concentrating.
2. according to the said a kind of skin-lightening cosmetic micro-emulsion stroma of claim 1, it is characterized in that said surfactant is one or both compositionss in polyoxyethylene hydrogenated Oleum Ricini or the polyoxyethylene castor oil.
3. claim 1 or 2 said skin-lightening cosmetics is characterized in that with the method for preparing of micro-emulsion stroma the step of this method for preparing is:
With Rhizoma Curcumae Longae extract, Rhizoma Belamcandae extract, mirabalan extract, vitamin E oil, surfactant and water mix homogeneously; Heating also remains under 50 ℃; This mixed system is at the uniform velocity stirred; Transparent stopping to occur to system heats; Naturally be cooled to room temperature; Again this mixed system is removed precipitated impurities through filtering to handle, then prepare required skin-lightening cosmetic micro-emulsion stroma.
4. according to the method for preparing of the said skin-lightening cosmetic of claim 2, it is characterized in that said mixed system is at the uniform velocity stirred is to adopt manual stirring or mechanical agitation with micro-emulsion stroma.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106137885A (en) * | 2016-09-28 | 2016-11-23 | 佛山慧创正元新材料科技有限公司 | A kind of infant cream containing prunus cerasifera extracting solution |
| CN107405374A (en) * | 2014-10-14 | 2017-11-28 | 比奥考金特有限责任公司 | Composition and method comprising Zingiber extract |
| CN107468589A (en) * | 2017-09-15 | 2017-12-15 | 广州赛莱拉干细胞科技股份有限公司 | A kind of lightening compositions and the skin care item containing the lightening compositions |
| CN107510629A (en) * | 2017-09-01 | 2017-12-26 | 广东丸美生物技术股份有限公司 | Extraction process, belamcanda chinensis extract and its application of belamcanda chinensis extract and moisturizing cream |
| CN108653144A (en) * | 2018-07-11 | 2018-10-16 | 中山市智联企业孵化器发展有限公司 | A kind of skin-lightening cosmetic |
| CN114187972A (en) * | 2021-12-10 | 2022-03-15 | 华东理工大学 | Calculation simulation method for screening functional ingredients of cosmetics |
| CN114642625A (en) * | 2022-02-17 | 2022-06-21 | 广东丸美生物技术股份有限公司 | Whitening and moisturizing traditional Chinese medicine composition and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101155576A (en) * | 2005-04-13 | 2008-04-02 | 株式会社资生堂 | Anti-wrinkle agent |
-
2011
- 2011-08-26 CN CN2011102478936A patent/CN102302423B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101155576A (en) * | 2005-04-13 | 2008-04-02 | 株式会社资生堂 | Anti-wrinkle agent |
Non-Patent Citations (2)
| Title |
|---|
| 《天然化妆品》 19880731 裴培 等编 中草药去斑化妆品 安徽科学技术出版社 第131-132页 1-4 , 第1版 * |
| 《日用化学工业》 20080630 杜志云 等 姜黄素类化合物及姜黄素衍生物对酪氨酸酶抑制作用的研究 第172-175页 1-4 第38卷, 第3期 * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107405374A (en) * | 2014-10-14 | 2017-11-28 | 比奥考金特有限责任公司 | Composition and method comprising Zingiber extract |
| CN106137885A (en) * | 2016-09-28 | 2016-11-23 | 佛山慧创正元新材料科技有限公司 | A kind of infant cream containing prunus cerasifera extracting solution |
| CN107510629A (en) * | 2017-09-01 | 2017-12-26 | 广东丸美生物技术股份有限公司 | Extraction process, belamcanda chinensis extract and its application of belamcanda chinensis extract and moisturizing cream |
| CN107468589A (en) * | 2017-09-15 | 2017-12-15 | 广州赛莱拉干细胞科技股份有限公司 | A kind of lightening compositions and the skin care item containing the lightening compositions |
| CN108653144A (en) * | 2018-07-11 | 2018-10-16 | 中山市智联企业孵化器发展有限公司 | A kind of skin-lightening cosmetic |
| CN114187972A (en) * | 2021-12-10 | 2022-03-15 | 华东理工大学 | Calculation simulation method for screening functional ingredients of cosmetics |
| CN114187972B (en) * | 2021-12-10 | 2024-02-09 | 华东理工大学 | Calculation simulation method for screening functional components of cosmetics |
| CN114642625A (en) * | 2022-02-17 | 2022-06-21 | 广东丸美生物技术股份有限公司 | Whitening and moisturizing traditional Chinese medicine composition and preparation method and application thereof |
| CN114642625B (en) * | 2022-02-17 | 2023-06-27 | 广东丸美生物技术股份有限公司 | Whitening and moisturizing traditional Chinese medicine composition and preparation method and application thereof |
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