CN102302423B - Micro-emulsion matrix for whitening cosmetics and preparation method for micro-emulsion matrix - Google Patents
Micro-emulsion matrix for whitening cosmetics and preparation method for micro-emulsion matrix Download PDFInfo
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Abstract
The invention discloses micro-emulsion matrix for whitening cosmetics and a preparation method for the micro-emulsion matrix. The micro-emulsion matrix for the whitening cosmetics is oil-in-water micro-emulsion using turmeric extract, blackberry lily extract and cherry plum extract as main active ingredients, and comprises the following components in part by weight: 3 to 7 parts of turmeric extract, 1 to 5 parts of blackberry lily extract, 2 to 8 parts of cherry plum extract, 10 to 36 parts of surfactant, 0.05 to 2 parts of vitamin E oil and 50 to 70 parts of distilled water. By reasonably optimizing the consumption of the turmeric extract, the blackberry lily extract and the cherry plum extract, the three substances are complementary, and all-around nursing on skin whitening is realized. The micro-emulsion matrix for the whitening cosmetics has the characteristics of high thermodynamic stability, good storage stability, good light transmission property, good corrosion resistance, higher diffusivity of the active ingredients, good skin permeability and whitening effect and the like; and when the micro-emulsion matrix is added into the conventional whitening cosmetics, the whitening effect of the whitening cosmetics can be effectively improved, so the micro-emulsion matrix has broad market.
Description
Technical field
The present invention relates to the cosmetics technical field, be specifically related to the skin-lightening cosmetic field, relate in particular to a kind of skin-lightening cosmetic micro-emulsion stroma and preparation method thereof.
Background technology
Whitening is an extremely important research field of cosmetics, Asia women never stops for the pursuit of light just as the mankind for the pursuit of whitening, all kinds of whitening and skin-protecting products generally occur like rain rear spring bamboo, wherein much take the chemical whitening agent of synthetic as main component, although short time successful, but large to skin irritation, produce a lot of negative effects.
Along with the concept of green safety becomes more and more popular, Skin whitening care cosmetics safety and effect become the focus that consumer and producer pay close attention to simultaneously.People have turned to sight the active substance of some natural extract, it extracts from natural material, chemical constitution and biological activity do not change, and its have multi-efficiency, lasting medicine stable, widely applicable, have no side effect or side effect very little, be the development trend of back to nature, science skin protection.
Along with people melanin is generated in recent years the continuous understanding of biological mechanism, seek from natural product safely and effectively that the whitening active substance becomes the cosmetics research focus, therefore excavate more natural material active component that skin is had a white-skinned face function and have very high economic worth and wide market prospect.
Microemulsion is by spontaneous formation such as water, oil and surfactants, and particle diameter is that the thermodynamic power of 10～100nm is learned stabilising system.At cosmetic field, large multi-product is emulsion, and its particle diameter is generally all greater than 400nm.
Microemulsion has the advantages that as a kind of specific form of emulsion general emulsion can't have: as thermodynamic stability is high, light transmission is good, antiseptic property is good and effective ingredient has higher diffusibility and percutaneous permeability etc.
Research emphasis for microemulsion system is to select suitable surfactant, consider nontoxicly, green, non-stimulated etc., also will seek the emulsification method consistent with surfactant simultaneously.
Summary of the invention
The object of the invention is to for existing deficiency, provide a kind of take natural plant extracts (liquid) as raw material, get by the preparation of microemulsified technique, has fine whitening effect, and the skin-lightening cosmetic micro-emulsion stroma of green safety, this micro-emulsion stroma can make the whitening performance of existing skin-lightening cosmetic be significantly improved.
Another object of the present invention provides the preparation method that above-mentioned skin-lightening cosmetic is used micro-emulsion stroma.
Above-mentioned purpose of the present invention is achieved by following scheme:
The inventor is for the present situation of present whitening product, various plants is carried out the extraction of active component, and study its extract (liquid) and whether skin is had whitening function, found that by research three Plant Extracts (liquid) have good whitening function to skin really, and each self-whitening principle is all different with approach, therefore the inventor considers again this three Plant Extracts (liquid) is reasonably arranged in pairs or groups, by optimizing its formula ratio, so that three's white-skinned face function can be complementary, and reach best whitening effect.
A kind of skin-lightening cosmetic micro-emulsion stroma, this micro-emulsion stroma are the water oil-packaging type micro-emulsions take Rhizoma Curcumae Longae extracting solution, Rhizoma Belamcandae extracting solution and mirabalan extracting solution as main active, specifically comprise each component of following parts by weight:
3～7 parts of Rhizoma Curcumae Longae extracts;
1～5 part of Rhizoma Belamcandae extract;
2～8 parts of mirabalan extracts;
10～36 parts in surfactant;
0.05～2 part of vitamin E oil;
50～70 parts of distilled water.
Above-mentioned Rhizoma Curcumae Longae extract is after the Rhizoma Curcumae Longae rhizome is pulverized, with 75% alcohol reflux 3 times after, and merge extractive liquid,, 5 times obtain Rhizoma Curcumae Longae extract after concentrating; The inventor is by studying rear discovery to this Rhizoma Curcumae Longae extract, and this Rhizoma Curcumae Longae extract can suppress the generation of dermal melanin, and has high oxidation resistance and whitening function, and healing that can also family members' skin scar reduces the formation of scar.
Above-mentioned Rhizoma Belamcandae extract is after Rhizoma Belamcandae is pulverized, behind 90% alcohol reflux 3 times, and merge extractive liquid,, five times obtain Rhizoma Belamcandae extract after concentrated; The inventor is by studying rear discovery to this Rhizoma Belamcandae extract, and this Rhizoma Belamcandae extract has good anti-aging effects, and moisturizing is effective, and can soften skin surface.
Above-mentioned mirabalan extract is to adopt commercially available mirabalan extract (ClairIu liquid), such as the hydrolysis mirabalan extract of Japanese firm's production; The mirabalan extract can be engulfed melanic by the establishment keratinocyte, thereby stops melanin to enter the effect that horny layer reaches whitening.
Above-mentioned surfactant is one or both compositionss in polyoxyethylene hydrogenated Oleum Ricini or the polyoxyethylene castor oil; Skin-lightening cosmetic of the present invention is with in the composition of raw materials of micro-emulsion stroma, its main active is Rhizoma Curcumae Longae extract, Rhizoma Belamcandae extract and mirabalan extract, although these three kinds of extracts are to adopt the extracting method of the special optimal design of the inventor to obtain, but wherein still comparison of ingredients is complicated, finally obtain limpid transparent micro-emulsion stroma in order to do, so the inventor is by screening the exhibiting high surface activating agent, finally obtain surfactant of the present invention, this surfactant has not only guaranteed microemulsified of the present invention, and has green, nontoxic and non-stimulated characteristics.
Said vitamin E oil plays auxiliary defying age in composition of raw materials, increase the effect of nutrient for skin.
The above-mentioned skin-lightening cosmetic preparation method of micro-emulsion stroma, its concrete steps are as follows:
According to the above-mentioned raw materials prescription, with Rhizoma Curcumae Longae extract, Rhizoma Belamcandae extract, the mirabalan extract, vitamin E oil, surfactant and water mix homogeneously, this moment, mixed system was also opaque, and some insoluble matter precipitations are arranged, heat and remain under 50 ℃ this moment, this mixed system is stirred at the uniform velocity (but manual stirring also can mechanical agitation, such as magnetic agitation etc.), after keeping a period of time, system occurs transparent, stopped heating, naturally be cooled to room temperature, this mixed system is still kept clear, this mixed system is processed after filtration removed precipitated impurities again, then prepares required skin-lightening cosmetic micro-emulsion stroma.
Compared with prior art, the present invention has following beneficial effect:
1. the present invention adopts Rhizoma Curcumae Longae extract, Rhizoma Belamcandae extract and mirabalan extract, by its consumption of reasonably optimizing, so that three kinds of materials are realized complementation, realizes the comprehensive nursing to skin-whitening;
2. Rhizoma Curcumae Longae extract of the present invention, Rhizoma Belamcandae extract and mirabalan extract, its extraction process is the inventor and gropes by great many of experiments design and data that rear optimization obtains, not only can realize the wherein effective separation of active component, and be conducive to the microemulsified technique in later stage;
3. microemulsified technique of the present invention is the characteristics for composition of raw materials of the present invention, and special optimal design, not only can effectively keep the active component of extract, and simple to operate, and microemulsified is effective;
4. skin-lightening cosmetic micro-emulsion stroma of the present invention, after tested its thermodynamic stability height, excellent storage stability, light transmission is good, antiseptic property is good, effective ingredient has higher diffusibility, percutaneous permeability, and whitening effect is good, add in the existing skin-lightening cosmetic and can effectively improve its whitening effect, have wide market.
The specific embodiment
Below in conjunction with specific embodiment the present invention is done further description, but specific embodiment is not done any restriction to the present invention.
Embodiment 1
The skin-lightening cosmetic micro-emulsion stroma of present embodiment, this micro-emulsion stroma are the water oil-packaging type micro-emulsions take Rhizoma Curcumae Longae extracting solution, Rhizoma Belamcandae extracting solution and mirabalan extracting solution as main active, specifically comprise each component of following parts by weight:
3.5 parts of Rhizoma Curcumae Longae extracts;
3 parts of Rhizoma Belamcandae extract;
6 parts of mirabalan extracts;
20 parts in surfactant;
0.05 part of vitamin E oil;
67 parts of distilled water.
Above-mentioned Rhizoma Curcumae Longae extract is after the Rhizoma Curcumae Longae rhizome is pulverized, with 75% alcohol reflux 3 times after, and merge extractive liquid,, 5 times obtain Rhizoma Curcumae Longae extract after concentrating.
Above-mentioned Rhizoma Belamcandae extract is after Rhizoma Belamcandae is pulverized, behind 90% alcohol reflux 3 times, and merge extractive liquid,, five times obtain Rhizoma Belamcandae extract after concentrated.
Above-mentioned mirabalan extract is to adopt commercially available mirabalan extract (ClairIu liquid).
Above-mentioned surfactant is polyoxyethylene hydrogenated Oleum Ricini.
Said vitamin E oil is the commercially available prod.
The above-mentioned skin-lightening cosmetic preparation method of micro-emulsion stroma, its concrete steps are as follows:
According to the above-mentioned raw materials prescription, with Rhizoma Curcumae Longae extract, Rhizoma Belamcandae extract, the mirabalan extract, vitamin E oil, surfactant and water mix homogeneously, this moment, mixed system was also opaque, and some insoluble matter precipitations are arranged, heat and remain under 50 ℃ this moment, this mixed system is at the uniform velocity stirred (magnetic agitation), after keeping a period of time, system occurs transparent, stopped heating is cooled to room temperature naturally, and this mixed system is still kept clear, again this mixed system is processed after filtration and removed precipitated impurities, then prepare required skin-lightening cosmetic micro-emulsion stroma.
Embodiment 2
The skin-lightening cosmetic micro-emulsion stroma of present embodiment, this micro-emulsion stroma each amounts of components in composition of raw materials was as follows, all the other were with embodiment 1:
7 parts of Rhizoma Curcumae Longae extracts;
1.5 parts of Rhizoma Belamcandae extract;
2 parts of mirabalan extracts;
20 parts in surfactant;
1 part of vitamin E oil;
69 parts of distilled water.
The present embodiment skin-lightening cosmetic uses the preparation method of micro-emulsion stroma with embodiment 1.
Embodiment 3
The skin-lightening cosmetic micro-emulsion stroma of present embodiment, this micro-emulsion stroma each amounts of components in composition of raw materials was as follows, all the other were with embodiment 1:
4 parts of Rhizoma Curcumae Longae extracts;
1 part of Rhizoma Belamcandae extract;
8 parts of mirabalan extracts;
30 parts in surfactant;
2 parts of vitamin E oils;
55 parts of distilled water.
The present embodiment skin-lightening cosmetic uses the preparation method of micro-emulsion stroma with embodiment 1.
Embodiment 4
The skin-lightening cosmetic micro-emulsion stroma of present embodiment, this micro-emulsion stroma each amounts of components in composition of raw materials was as follows, all the other were with embodiment 1:
5 parts of Rhizoma Curcumae Longae extracts;
4 parts of Rhizoma Belamcandae extract;
3 parts of mirabalan extracts;
16 parts in surfactant;
2 parts of vitamin E oils;
70 parts of distilled water.
The present embodiment skin-lightening cosmetic uses the preparation method of micro-emulsion stroma with embodiment 1.
Embodiment 5 stability experiments
1, light stability experiment
The skin-lightening cosmetic of embodiment 1～4 is respectively charged in the vial with micro-emulsion stroma, sealing places under the daylight, and light at room temperature was according to 15 days, and the result shows that the skin-lightening cosmetic of embodiment 1～4 all keeps the clear outward appearance with micro-emulsion stroma, color does not change, without phenomenons such as layerings.
2, temperature stability experiment
The skin-lightening cosmetic of embodiment 1 is loaded on respectively in several vials with micro-emulsion stroma, investigates three months as under 4 ℃, 25 ℃, 40 ℃ and 60 ℃ of four temperature after the sealing; In like manner also respectively the skin-lightening cosmetic of embodiment 2～4 is carried out identical experiment with micro-emulsion stroma.
At any time sampling is observed in the middle of 3 months, and the result shows that under four temperature skin-lightening cosmetic of the present invention all keeps the outward appearance of clear with micro-emulsion stroma, without lamination.
Embodiment 6 whitening effect evaluation experimentals
Come Evaluation operation example 1～4 skin-lightening cosmetic whitening effect of micro-emulsion stroma by operational test.The skin-lightening cosmetic that the skin-lightening cosmetic that test is divided into embodiment 1 preparation prepares with micro-emulsion stroma, embodiment 4 with the skin-lightening cosmetic of micro-emulsion stroma, embodiment 3 preparations with the skin-lightening cosmetic of micro-emulsion stroma, embodiment 2 preparations is with micro-emulsion stroma and do not add the product (comparable group) that skin-lightening cosmetic of the present invention is used micro-emulsion stroma, totally five experimental grouies.
30～40 years old women are totally 50 depositions of utilizing the ultra-vioket radiation device to cause dermal melanin, they are divided into arbitrarily two groups, every day, each touched an amount of above-mentioned five experimental grouies on the arm after washing for twice more sooner or later, continuous two months, detects by an unaided eye and must improve to estimate whitening effect on arm.Bearing performance is as shown in table 1.
Table 1 whitening effect evaluation result
| ? | Effectively | Effective a little | Invalid | Effective percentage (%) |
| Embodiment 1 skin-lightening cosmetic micro-emulsion stroma | 40 | 7 | 3 | 94 |
| Embodiment 2 skin-lightening cosmetic micro-emulsion stromas | 42 | 6 | 2 | 96 |
| Embodiment 3 skin-lightening cosmetic micro-emulsion stromas | 40 | 8 | 2 | 96 |
| Embodiment 4 skin-lightening cosmetic micro-emulsion stromas | 43 | 4 | 3 | 94 |
| Do not add the skin-lightening cosmetic of the present invention product of micro-emulsion stroma | 5 | 10 | 35 | 30 |
Can find out from result's contrast of table 1, skin-lightening cosmetic of the present invention has good skin-whitening effect really with micro-emulsion stroma, and, can not observe stimulation to skin most of those who are investigated that skin-lightening cosmetic of the present invention is used at skin with micro-emulsion stroma.
Claims (3)
1. a skin-lightening cosmetic micro-emulsion stroma is characterized in that this skin-lightening cosmetic micro-emulsion stroma is the water oil-packaging type micro-emulsion take Rhizoma Curcumae Longae extracting solution, Rhizoma Belamcandae extracting solution and mirabalan extracting solution as main active, and specifically each component by following parts by weight forms:
3 ~ 7 parts of Rhizoma Curcumae Longae extracts;
1 ~ 5 part of Rhizoma Belamcandae extract;
2 ~ 8 parts of mirabalan extract C lairIu liquid;
10 ~ 36 parts in surfactant;
0.05 ~ 2 part of vitamin E oil;
50 ~ 70 parts of distilled water;
Above-mentioned Rhizoma Curcumae Longae extract is after the Rhizoma Curcumae Longae rhizome is pulverized, with 75% alcohol reflux 3 times after, and merge extractive liquid,, 5 times obtain Rhizoma Curcumae Longae extract after concentrating;
Above-mentioned Rhizoma Belamcandae extract is after Rhizoma Belamcandae is pulverized, behind 90% alcohol reflux 3 times, merge extractive liquid,, five times after concentrated Rhizoma Belamcandae extract.
2. described a kind of skin-lightening cosmetic micro-emulsion stroma according to claim 1 is characterized in that described surfactant is one or both compositionss in polyoxyethylene hydrogenated Oleum Ricini or the polyoxyethylene castor oil.
3. a claim 1 or 2 described skin-lightening cosmetics are with the preparation method of micro-emulsion stromas, the step that it is characterized in that this preparation method is: with Rhizoma Curcumae Longae extract, Rhizoma Belamcandae extract, mirabalan extract, vitamin E oil, surfactant and water mix homogeneously, heating also remains under 50 ℃, this mixed system is at the uniform velocity stirred, transparent stopped heating appears to system, naturally be cooled to room temperature, again this mixed system is processed after filtration and removed precipitated impurities, then prepare required skin-lightening cosmetic micro-emulsion stroma.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108653144A (en) * | 2018-07-11 | 2018-10-16 | 中山市智联企业孵化器发展有限公司 | A kind of skin-lightening cosmetic |
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| CN107405374A (en) * | 2014-10-14 | 2017-11-28 | 比奥考金特有限责任公司 | Composition and method comprising Zingiber extract |
| CN106137885A (en) * | 2016-09-28 | 2016-11-23 | 佛山慧创正元新材料科技有限公司 | A kind of infant cream containing prunus cerasifera extracting solution |
| CN107510629A (en) * | 2017-09-01 | 2017-12-26 | 广东丸美生物技术股份有限公司 | Extraction process, belamcanda chinensis extract and its application of belamcanda chinensis extract and moisturizing cream |
| CN107468589A (en) * | 2017-09-15 | 2017-12-15 | 广州赛莱拉干细胞科技股份有限公司 | A kind of lightening compositions and the skin care item containing the lightening compositions |
| CN114187972B (en) * | 2021-12-10 | 2024-02-09 | 华东理工大学 | Calculation simulation method for screening functional components of cosmetics |
| CN114642625B (en) * | 2022-02-17 | 2023-06-27 | 广东丸美生物技术股份有限公司 | Whitening and moisturizing traditional Chinese medicine composition and preparation method and application thereof |
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| KR101323487B1 (en) * | 2005-04-13 | 2013-10-31 | 가부시키가이샤 시세이도 | Antiwrinkle agent |
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| CN108653144A (en) * | 2018-07-11 | 2018-10-16 | 中山市智联企业孵化器发展有限公司 | A kind of skin-lightening cosmetic |
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