CN108653061A - A kind of naturally moist Anti-bacterium hand cream - Google Patents
A kind of naturally moist Anti-bacterium hand cream Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The invention mainly relates to natural specific function skin care item processing technique fields, disclose a kind of naturally moist Anti-bacterium hand cream, are made of following raw material：Rice, Chinese yam, Cortex Magnoliae Officinalis, eupatorium, Pogostemon cablin, Poria cocos, cape jasmine, lactic acid bacteria, Saccharomyces cerevisiae；Naturally moist Anti-bacterium hand cream provided by the invention, natural health, without any stimulating component, aromatic flavour is easy to absorb, and moisturizing is carried out to baby's hand, antibiotic and sterilizing, avoid baby often disorderly grab thing and eat hand make germ from mouth enter body caused by disease；Cortex Magnoliae Officinalis, eupatorium, Pogostemon cablin, Poria cocos and cape jasmine are crushed laggard row progress high temperature to steam and decoct, promotes active ingredient to leach, increases nourishing and the antibacterial effect of hand lotion, protect gastrointestinal function, avoiding hand lotion from generating skin stimulates；Lactobacillus-fermented is carried out after polished rice without husking is crushed, increases B family vitamin, the content of nicotine element and vitamin E, is promoted to absorb, is effectively nourished hand skin.
Description
Technical field
The invention mainly relates to natural specific function skin care item processing technique field more particularly to a kind of naturally moist antibacterials
Hand lotion.
Background technology
Baby is a kind of special population, and baby often eats hand, so hand lotion should keep natural green, safe and healthy,
The not harmful components such as spirituosity, heavy metal, mineral oil, hormone, pigment, essence and preservative, to avoid hand lotion itself to baby
The health of youngster generates harm；And baby likes disorderly grabbing thing, is often stained with bacterium on hand, it is therefore desirable to which hand lotion has
Antibacterial functions generate harm to avoid extraneous germ to the health of baby；Pregnant woman is a kind of special population, the shield used
Skin product must be safe and healthy, pure natural, not spirituosity, heavy metal, mineral oil, hormone, pigment, essence and preservative etc..
There are many hand lotion brand of existing market, the hand lotions of the various packagings also very eyeball of sound-absorbing consumer, but big
More hand lotions all only play moistening effect, and without apparent antibacterial functions, antibacterial functions are all the changes that antibiotic property is added
Reagent is learned, the skin of baby can be caused to stimulate, or even generates allergy and red and swollen symptom, danger is generated to the skin health of baby
Evil；102078277 A of patent document CN disclose the antibacterial plant essence hand cream that a kind of baby and pregnant woman are applicable in, and are formulated and are
20 grams of chamomile, 20 grams of honeysuckle stem, 10 grams of folium artemisiae argyi, 20 grams of dandelion, 20 grams of wild chrysanthemum, 25 grams of aloe essence, alpha-tocopherol acetate
10 grams, 10 grams of jojoba oil, 10 grams of bisabolol, 30 grams of PEG-75 lanolin, 2-5 grams of nano-titanium dioxide and weight ratio are 2-
5 grams of basic zirconium phosphate silver-carrying nano compounds, the content through the bisabolol that converts is 5.41 ~ 5.59%, and the general addition of bisabolol
Amount is 0.2 ~ 1.0%, in most cases 0.2 ~ 0.5%, and for bisabolol, there are an optimum concentrations, exceed this
One concentration, validity reduce instead, therefore the additive amount of the bisabolol in the application is significantly higher, and antibiotic property drops instead
It is low；Basic zirconium phosphate silver-carrying nano compound is antibacterial agent simultaneously, also only makes an addition to the articles for use such as resin at present, also few application
In skin care item, therefore directly make an addition in the hand lotion that baby and pregnant woman use with some potential safety problems；Therefore market
Need it is a kind of can moisturizing but also antibiotic and sterilizing natural hand lotion.
Invention content
In order to make up the defect of prior art, the object of the present invention is to provide a kind of naturally moist Anti-bacterium hand creams.
A kind of naturally moist Anti-bacterium hand cream, is made of the raw material of following parts by weight：Rice 61 ~ 63, Chinese yam 35 ~ 37, thickness
Piao 14 ~ 16, eupatorium 11 ~ 13, Pogostemon cablin 11 ~ 13, Poria cocos 11 ~ 13, cape jasmine 8 ~ 10, lactic acid bacteria 3 ~ 5, Saccharomyces cerevisiae 3 ~ 5.
The rice, is the fresh polished rice without husking, and water content is 8 ~ 12%.
The lactic acid bacteria takes precipitation to mix after re-activation, can be directly used for fermenting, by the bacterial strain of following parts by weight
Composition：Lactobacillus acidophilus 19 ~ 21, lactobacillus bulgaricus 17 ~ 19, Lactobacillus delbrueckii 16 ~ 18, lactobacillus buchneri 11 ~ 13.
A kind of preparation method of natural moist Anti-bacterium hand cream, includes the following steps：
（1）Cortex Magnoliae Officinalis, eupatorium, Pogostemon cablin, Poria cocos and cape jasmine are mixed, 200 ~ 240 mesh are crushed to, obtains traditional Chinese medicine powder, traditional Chinese medicine powder is added
The deionized water of 5 ~ 7 times of amounts of weight, steams 40 ~ 60 minutes in 124 ~ 128 DEG C, takes out, and it is original 1/6 ~ 1/ to decoct to volume
5, promote active ingredient to leach, increases the fragrance of hand lotion and nourish antibacterial effect, protect gastrointestinal function, avoid hand lotion to skin
Skin generates stimulation, obtains decocting for Chinese herbal medicine liquid；
（2）Rice is crushed to 60 ~ 80 mesh, obtains rice flour, deionized water is added into rice flour, it is 45 ~ 50% to adjust water content, leaching
Bubble 3 ~ 4 hours accesses lactic acid bacteria, is uniformly mixed, and ferments 10 ~ 12 hours in 41 ~ 43 DEG C, increases B family vitamin, nicotine element and dimension
The content of raw element E, promotes to absorb, effectively nourishes hand skin, obtain one time fermentation material；
（3）It is 0 ~ 6% that one time fermentation material, which is freeze-dried to water content, increases the porosity of rice flour, refines rice flour granularity, is added
The deionized water of 1.2 ~ 1.6 times of amounts of rice flour weight, is uniformly mixed, continues fermentation 2 ~ 3 days in 30 ~ 32 DEG C, is conducive in rice flour small point
The release of sub- nutritional ingredient and middle macromolecular active ingredient are sufficiently converted into small-molecule substance, improve rice utilization rate, promote flesh
Absorption of the skin to nutritional ingredient, improves the moisturizing effect of hand lotion, obtains secondary fermentation material；
（4）Decocting for Chinese herbal medicine liquid is added into secondary fermentation material, is uniformly mixed, ferments 2 ~ 3 days in 32 ~ 34 DEG C, promotes to have in Chinese medicine
The leaching of ingredient is imitated, extraction process obtains fermentation material three times without high temperature and pressure, energy saving and cost；
（5）Chinese yam is cleaned, is beaten, obtains Chinese yam pulp, fermentation material three times is added in Chinese yam pulp and Saccharomyces cerevisiae, is uniformly mixed, in
24 ~ 26 DEG C of ferment at constant temperature 24 ~ 36 hours promote saccharomycete proliferation, increase the nutrition of hand lotion and nourish ingredient, freeze-drying is extremely
Water content is 45 ~ 50%, is centrifuged 13 ~ 15 minutes in 4000 revs/min, except precipitation keeps hand lotion exquisiteness refreshing through two-period form homogeneous
It is sliding, it is conducive to absorb, hand skin is kept to moisten health, obtains and naturally moisten Anti-bacterium hand cream；
（6）Packaging, radio sterilization are examined, and are obtained and are naturally moistened Anti-bacterium hand cream finished product.
The step（5）Two sections of homogeneous, homogenizing temperature be 41 ~ 43 DEG C, first segment homogenization pressure be 27.4 ~ 28.9MPa,
Second segment homogenization pressure is 15.2 ~ 16.6MPa.
The step（6）Radio sterilization, dose of radiation be 34.6 ~ 36.3kGy.
The application method of the natural moist Anti-bacterium hand cream, is suitable for baby and pregnant woman, washes one's hands or does not wash one's hands desirable
Appropriate naturally moist Anti-bacterium hand cream is applied on hand skin, is massaged into absorption, germ is removed after washing one's hands, hand lotion plays guarantor
Wet moist effect, is smeared when not washing one's hands, and hand lotion can kill germ on hand and nourish skin, to hand into
The preferable protection of row.
It is an advantage of the invention that：Naturally moist Anti-bacterium hand cream provided by the invention, natural health, without any irritation at
Point, aromatic flavour is easy to absorb, and moisturizing can be carried out to hand, and antibiotic and sterilizing avoids baby from often disorderly grabbing thing and eat
Hand make germ from mouth enter body caused by disease；Cortex Magnoliae Officinalis, eupatorium, Pogostemon cablin, Poria cocos and cape jasmine are crushed laggard row to carry out
High temperature is steamed and is decocted, and active ingredient is promoted to leach, and is increased the fragrance of hand lotion and is nourished antibacterial effect, protects gastrointestinal function,
Hand lotion is avoided to generate stimulation to skin；Immersion and lactobacillus-fermented are carried out after fresh polished rice without husking is crushed, and increase B
The content of family vitamin, nicotine element and vitamin E promotes to absorb, effectively nourishes hand skin；It is dry that freezing is carried out after one time fermentation
It is dry, increase the porosity of rice flour, refine rice flour granularity, then ferment when lactic acid bacteria low temperature is long, is conducive to rice flour small molecular and seeks
The release and middle macromolecular active ingredient formed point are sufficiently converted into small-molecule substance, improve rice utilization rate, promote skin pair
The absorption of nutritional ingredient improves the moisturizing effect of hand lotion；Decocting for Chinese herbal medicine liquid is added in secondary fermentation material, lactic acid bacteria is continued on through
Ferment when low temperature is long, promote the leaching of active ingredient in Chinese medicine, extraction process without high temperature and pressure, it is energy saving and at
This；Chinese yam pulp and yeast powder are added into fermentation material three times, continues to ferment in short-term, promotes saccharomycete proliferation, increases handguard
The nutrition of frost and nourishing ingredient, are freeze-dried after fermentation, reduce moisture, while can increase raw material porosity, promoted
Into there is ingredient release in raw material, the moist and antibacterial functions of hand lotion are improved, are centrifuged after freeze-drying, removal precipitation is laggard
Two sections of homogeneous of row, keep hand lotion exquisiteness smooth, are conducive to absorb, baby's hand skin is kept to moisten health；Using simple, wash one's hands and
It does not wash one's hands and can be used, germ is removed after washing one's hands, hand lotion plays the effect of moisturizing, smeared when not washing one's hands, handguard
Frost can kill germ on hand and nourish skin, preferably be protected to hand.
Specific implementation mode
Illustrate the present invention with specific embodiment below.
Embodiment 1
A kind of naturally moist Anti-bacterium hand cream, is made of the raw material of following parts by weight：Rice 61, Chinese yam 35, Cortex Magnoliae Officinalis 14, eupatorium
11, Pogostemon cablin 11, Poria cocos 11, cape jasmine 8, lactic acid bacteria 3, Saccharomyces cerevisiae 3.
The rice, is the fresh polished rice without husking, and water content is 8 ~ 12%.
The lactic acid bacteria takes precipitation to mix after re-activation, can be directly used for fermenting, by the bacterial strain of following parts by weight
Composition：Lactobacillus acidophilus 19, lactobacillus bulgaricus 17, Lactobacillus delbrueckii 16, lactobacillus buchneri 11.
A kind of preparation method of natural moist Anti-bacterium hand cream, includes the following steps：
（1）Cortex Magnoliae Officinalis, eupatorium, Pogostemon cablin, Poria cocos and cape jasmine are mixed, 200 mesh are crushed to, obtains traditional Chinese medicine powder, traditional Chinese medicine powder weight 5 is added
The deionized water of amount again, steams 40 minutes in 124 DEG C, takes out, and it is 1/6 originally to decoct to volume, and active ingredient is promoted to leach,
Increase the fragrance of hand lotion and nourish antibacterial effect, protect gastrointestinal function, hand lotion is avoided to generate stimulation to skin, obtains Chinese medicine and decoct
Boil liquid；
（2）Rice is crushed to 60 mesh, obtains rice flour, deionized water is added into rice flour, it is 45 ~ 50% to adjust water content, impregnates 3
Hour, lactic acid bacteria is accessed, is uniformly mixed, is fermented 10 hours in 41 DEG C, containing for B family vitamin, nicotine element and vitamin E is increased
Amount promotes to absorb, effectively nourishes hand skin, obtain one time fermentation material；
（3）It is 0 ~ 6% that one time fermentation material, which is freeze-dried to water content, increases the porosity of rice flour, refines rice flour granularity, is added
The deionized water of 1.2 times of amounts of rice flour weight, is uniformly mixed, and continues fermentation 2 days in 30 DEG C, is conducive to rice flour small molecular nutritional ingredient
Release and middle macromolecular active ingredient be sufficiently converted into small-molecule substance, improve rice utilization rate, promote skin to nutrition at
The absorption divided, improves the moisturizing effect of hand lotion, obtains secondary fermentation material；
（4）Decocting for Chinese herbal medicine liquid is added into secondary fermentation material, is uniformly mixed, ferments 2 days in 32 DEG C, promotes active ingredient in Chinese medicine
Leaching, extraction process obtains fermentation material three times without high temperature and pressure, energy saving and cost；
（5）Chinese yam is cleaned, is beaten, obtains Chinese yam pulp, fermentation material three times is added in Chinese yam pulp and Saccharomyces cerevisiae, is uniformly mixed, in
24 DEG C of ferment at constant temperature 24 hours promote saccharomycete proliferation, increase the nutrition of hand lotion and nourish ingredient, freeze-drying to water content
It is 45 ~ 50%, is centrifuged 13 minutes in 4000 revs/min, except precipitation, through two-period form homogeneous, homogenizing temperature is 41 DEG C, and first segment is equal
Matter pressure is 27.4MPa, and second segment homogenization pressure is 15.2MPa, keeps hand lotion exquisiteness smooth, is conducive to absorb, keeps hand muscle
Skin moistens health, obtains and naturally moistens Anti-bacterium hand cream；
（6）Packaging, radio sterilization, dose of radiation 34.6kGy are examined, and are obtained and are naturally moistened Anti-bacterium hand cream finished product.
The application method of the natural moist Anti-bacterium hand cream, is suitable for baby and pregnant woman, washes one's hands or does not wash one's hands desirable
Appropriate naturally moist Anti-bacterium hand cream is applied on hand skin, is massaged into absorption, germ is removed after washing one's hands, hand lotion plays guarantor
Wet moist effect, is smeared when not washing one's hands, and hand lotion can kill germ on hand and nourish skin, to hand into
The preferable protection of row.
Embodiment 2
A kind of naturally moist Anti-bacterium hand cream, is made of the raw material of following parts by weight：Rice 62, Chinese yam 36, Cortex Magnoliae Officinalis 15, eupatorium
12, Pogostemon cablin 12, Poria cocos 12, cape jasmine 9, lactic acid bacteria 4, Saccharomyces cerevisiae 4.
The rice, is the fresh polished rice without husking, and water content is 8 ~ 12%.
The lactic acid bacteria takes precipitation to mix after re-activation, can be directly used for fermenting, by the bacterial strain of following parts by weight
Composition：Lactobacillus acidophilus 20, lactobacillus bulgaricus 18, Lactobacillus delbrueckii 17, lactobacillus buchneri 12.
A kind of preparation method of natural moist Anti-bacterium hand cream, includes the following steps：
（1）Cortex Magnoliae Officinalis, eupatorium, Pogostemon cablin, Poria cocos and cape jasmine are mixed, 220 mesh are crushed to, obtains traditional Chinese medicine powder, traditional Chinese medicine powder weight 6 is added
The deionized water of amount again, steams 50 minutes in 126 DEG C, takes out, and it is 1/6 originally to decoct to volume, and active ingredient is promoted to leach,
Increase the fragrance of hand lotion and nourish antibacterial effect, protect gastrointestinal function, hand lotion is avoided to generate stimulation to skin, obtains Chinese medicine and decoct
Boil liquid；
（2）Rice is crushed to 60 mesh, obtains rice flour, deionized water is added into rice flour, it is 45 ~ 50% to adjust water content, impregnates 4
Hour, lactic acid bacteria is accessed, is uniformly mixed, is fermented 11 hours in 42 DEG C, containing for B family vitamin, nicotine element and vitamin E is increased
Amount promotes to absorb, effectively nourishes hand skin, obtain one time fermentation material；
（3）It is 0 ~ 6% that one time fermentation material, which is freeze-dried to water content, increases the porosity of rice flour, refines rice flour granularity, is added
The deionized water of 1.4 times of amounts of rice flour weight, is uniformly mixed, and continues fermentation 2 days in 31 DEG C, is conducive to rice flour small molecular nutritional ingredient
Release and middle macromolecular active ingredient be sufficiently converted into small-molecule substance, improve rice utilization rate, promote skin to nutrition at
The absorption divided, improves the moisturizing effect of hand lotion, obtains secondary fermentation material；
（4）Decocting for Chinese herbal medicine liquid is added into secondary fermentation material, is uniformly mixed, ferments 3 days in 33 DEG C, promotes active ingredient in Chinese medicine
Leaching, extraction process obtains fermentation material three times without high temperature and pressure, energy saving and cost；
（5）Chinese yam is cleaned, is beaten, obtains Chinese yam pulp, fermentation material three times is added in Chinese yam pulp and Saccharomyces cerevisiae, is uniformly mixed, in
25 DEG C of ferment at constant temperature 30 hours promote saccharomycete proliferation, increase the nutrition of hand lotion and nourish ingredient, freeze-drying to water content
It is 45 ~ 50%, is centrifuged 14 minutes in 4000 revs/min, except precipitation, through two-period form homogeneous, homogenizing temperature is 42 DEG C, and first segment is equal
Matter pressure is 27.8MPa, and second segment homogenization pressure is 15.7MPa, keeps hand lotion exquisiteness smooth, is conducive to absorb, keeps hand muscle
Skin moistens health, obtains and naturally moistens Anti-bacterium hand cream；
（6）Packaging, radio sterilization, dose of radiation 35.3kGy are examined, and are obtained and are naturally moistened Anti-bacterium hand cream finished product.
The application method of the natural moist Anti-bacterium hand cream, is suitable for baby and pregnant woman, washes one's hands or does not wash one's hands desirable
Appropriate naturally moist Anti-bacterium hand cream is applied on hand skin, is massaged into absorption, germ is removed after washing one's hands, hand lotion plays guarantor
Wet moist effect, is smeared when not washing one's hands, and hand lotion can kill germ on hand and nourish skin, to hand into
The preferable protection of row.
Embodiment 3
A kind of naturally moist Anti-bacterium hand cream, is made of the raw material of following parts by weight：Rice 63, Chinese yam 37, Cortex Magnoliae Officinalis 16, eupatorium
13, Pogostemon cablin 13, Poria cocos 13, cape jasmine 10, lactic acid bacteria 5, Saccharomyces cerevisiae 5.
The rice, is the fresh polished rice without husking, and water content is 8 ~ 12%.
The lactic acid bacteria takes precipitation to mix after re-activation, can be directly used for fermenting, by the bacterial strain of following parts by weight
Composition：Lactobacillus acidophilus 21, lactobacillus bulgaricus 19, Lactobacillus delbrueckii 18, lactobacillus buchneri 13.
A kind of preparation method of natural moist Anti-bacterium hand cream, includes the following steps：
（1）Cortex Magnoliae Officinalis, eupatorium, Pogostemon cablin, Poria cocos and cape jasmine are mixed, 240 mesh are crushed to, obtains traditional Chinese medicine powder, traditional Chinese medicine powder weight 7 is added
The deionized water of amount again, steams 60 minutes in 128 DEG C, takes out, and it is 1/5 originally to decoct to volume, and active ingredient is promoted to leach,
Increase the fragrance of hand lotion and nourish antibacterial effect, protect gastrointestinal function, hand lotion is avoided to generate stimulation to skin, obtains Chinese medicine and decoct
Boil liquid；
（2）Rice is crushed to 80 mesh, obtains rice flour, deionized water is added into rice flour, it is 45 ~ 50% to adjust water content, impregnates 4
Hour, lactic acid bacteria is accessed, is uniformly mixed, is fermented 12 hours in 43 DEG C, containing for B family vitamin, nicotine element and vitamin E is increased
Amount promotes to absorb, effectively nourishes hand skin, obtain one time fermentation material；
（3）It is 0 ~ 6% that one time fermentation material, which is freeze-dried to water content, increases the porosity of rice flour, refines rice flour granularity, is added
The deionized water of 1.6 times of amounts of rice flour weight, is uniformly mixed, and continues fermentation 3 days in 32 DEG C, is conducive to rice flour small molecular nutritional ingredient
Release and middle macromolecular active ingredient be sufficiently converted into small-molecule substance, improve rice utilization rate, promote skin to nutrition at
The absorption divided, improves the moisturizing effect of hand lotion, obtains secondary fermentation material；
（4）Decocting for Chinese herbal medicine liquid is added into secondary fermentation material, is uniformly mixed, ferments 3 days in 34 DEG C, promotes active ingredient in Chinese medicine
Leaching, extraction process obtains fermentation material three times without high temperature and pressure, energy saving and cost；
（5）Chinese yam is cleaned, is beaten, obtains Chinese yam pulp, fermentation material three times is added in Chinese yam pulp and Saccharomyces cerevisiae, is uniformly mixed, in
26 DEG C of ferment at constant temperature 36 hours promote saccharomycete proliferation, increase the nutrition of hand lotion and nourish ingredient, freeze-drying to water content
It is 45 ~ 50%, is centrifuged 15 minutes in 4000 revs/min, except precipitation, through two-period form homogeneous, homogenizing temperature is 43 DEG C, and first segment is equal
Matter pressure is 28.9MPa, and second segment homogenization pressure is 16.6MPa, keeps hand lotion exquisiteness smooth, is conducive to absorb, keeps hand muscle
Skin moistens health, obtains and naturally moistens Anti-bacterium hand cream；
（6）Packaging, radio sterilization, dose of radiation 36.3kGy are examined, and are obtained and are naturally moistened Anti-bacterium hand cream finished product.
The application method of the natural moist Anti-bacterium hand cream, is suitable for baby and pregnant woman, washes one's hands or does not wash one's hands desirable
Appropriate naturally moist Anti-bacterium hand cream is applied on hand skin, is massaged into absorption, germ is removed after washing one's hands, hand lotion plays guarantor
Wet moist effect, is smeared when not washing one's hands, and hand lotion can kill germ on hand and nourish skin, to hand into
The preferable protection of row.
Comparative example 1
Remove rice, remaining preparation and application, with embodiment 1.
Comparative example 2
Remove Chinese yam, remaining preparation and application, with embodiment 1.
Comparative example 3
Remove Cortex Magnoliae Officinalis, remaining preparation and application, with embodiment 1.
Comparative example 4
Remove eupatorium, remaining preparation and application, with embodiment 1.
Comparative example 5
Remove Pogostemon cablin, remaining preparation and application, with embodiment 1.
Comparative example 6
Remove Poria cocos, remaining preparation and application, with embodiment 1.
Comparative example 7
Remove cape jasmine, remaining preparation and application, with embodiment 1.
Comparative example 8
Remove lactic acid bacteria, remaining preparation and application, with embodiment 1.
Comparative example 9
Remove Saccharomyces cerevisiae, remaining preparation and application, with embodiment 1.
Comparative example 10
Removal step（3）In freeze-drying, remaining preparation and application, with embodiment 1.
Comparative example 11
Removal step（3）In fermentation, remaining preparation and application, with embodiment 1.
Comparative example 12
Removal step（4）In fermentation, remaining preparation and application, with embodiment 1.
Comparative example 13
Removal step（5）In fermentation, remaining preparation and application, with embodiment 1.
Comparative example 14
Step（5）In freeze-drying be changed to dry, remaining preparation and application, with embodiment 1.
Comparative example 15
Removal step（5）In two-period form homogeneous, remaining preparation and application, with embodiment 1.
Comparative example 16
Existing 102078277 A of patent document CN disclose the antibacterial plant essence hand cream that a kind of baby and pregnant woman are applicable in.
The safety detection of embodiment hand lotion：
Examination criteria：《Cosmetics health specification》(version in 2007)；
The present invention is through mammalian cells in vitro chromosomal aberration test, and as a result mammalian cells in vitro chromosome is undistorted anti-
It answers.
For the present invention through mammalian cells in vitro gene mutation test, the outer mammalian cell gene of effective aspect is prominent without gene
Become reaction.
For the present invention through mammal bone marrow cell chromosomal aberration test, as a result mammal bone marrow cell dyeing is undistorted
Reaction.
The present invention is through Testicular Germ Cell chromosomal aberration test, the as a result undistorted reaction of Testicular Germ Cell chromosome.
The present invention is through tertogenicity test, as a result without being reacted through teratogenesis.
The present invention is passed through to more skin irritant tests of skin irritation/corrosion test, the results showed that the present invention to skin without
Stimulation.
The moistening effect of embodiment and comparative example hand lotion：
The baby 190 that the age is 0 ~ 1 years old, skin health are randomly choosed, no skin allergy history is randomly divided into 19 groups, every group 10
Position, respectively embodiment group, comparative example group, embodiment group and comparative example group use the hand lotion of the group, subject's left hand respectively
Labeled as tested area, the right hand is labeled as control zone, and technical staff uses moisture content of skin tester Corneometer CM825
The moisture content of skin of test subject 5 times, results are averaged, and the hand lotion of the group is used after subject's cleaning hand, tested
Person uses moisture content of skin tester after this group of hand lotion 0.5h, 1h, 2h, 3h is used continuously, by technical staff
The hand skin water content of Corneometer CM825 test subjects 5 times, results are averaged, embodiment and comparative example shield
The moistening effect of hand frost is shown in Table 1.
Table 1：The moistening effect of embodiment and comparative example hand lotion
From the results shown in Table 1, the natural of embodiment moistens Anti-bacterium hand cream, baby's hand skin can be made long after use
Kubo holds higher water content, illustrates that naturally moist Anti-bacterium hand cream provided by the invention has good moistening effect.
The antibacterial effect of embodiment and comparative example hand lotion：
The hand lotion of embodiment and comparative example deionized water is diluted 10 times, obtains each group hand lotion dilution, large intestine bar purchased in market
Bacterium plating medium is down flat plate after sterilizing, quantity is 200, carries out E. coli broth in tablet after tablet is solid
The viable count of coating, bacterium solution is 1.0 × 108CFU/ml punches tablet after tablet moisture absorption, is randomly divided into 20
Group, every group 10, respectively embodiment group, comparative example group and blank group, embodiment group and comparative example group are inoculated in hole respectively
The 200 μ l of hand lotion dilution of the group, blank group are inoculated with 200 μ l sterile waters, in 37 DEG C of constant temperature incubations 24 hours, measure inhibition zone
Diameter (mm), results are averaged, and the antibacterial effect of embodiment and comparative example hand lotion is shown in Table 2.
Table 2：The antibacterial effect of embodiment and comparative example hand lotion
Note："+" indicates fungistatic effect, and quantity more multiple-effect fruit is better, and "-" indicates no fungistatic effect.
From the results shown in Table 2, the natural of embodiment moistens Anti-bacterium hand cream, and the diameter of tested rear inhibition zone is apparent
It is big compared with comparative example, to baby often in contact with pathogenic bacteria Escherichia coli have good inhibiting effect, illustrate provided by the invention
Naturally moist Anti-bacterium hand cream has good antibacterial effect.
Claims (7)
1. a kind of naturally moist Anti-bacterium hand cream, which is characterized in that be made of the raw material of following parts by weight：Rice 61 ~ 63, Chinese yam
35 ~ 37, Cortex Magnoliae Officinalis 14 ~ 16, eupatorium 11 ~ 13, Pogostemon cablin 11 ~ 13, Poria cocos 11 ~ 13, cape jasmine 8 ~ 10, lactic acid bacteria 3 ~ 5, Saccharomyces cerevisiae 3 ~
5。
2. naturally moistening Anti-bacterium hand cream according to claim 1, which is characterized in that the rice, for without husking
Fresh polished rice, water content are 8 ~ 12%.
3. naturally moistening Anti-bacterium hand cream according to claim 1, which is characterized in that the lactic acid bacteria, through re-activation
After take precipitation mix, can be directly used for fermenting, be made of the bacterial strain of following parts by weight：Lactobacillus acidophilus 19 ~ 21, bulgarian milk
Bacillus 17 ~ 19, Lactobacillus delbrueckii 16 ~ 18, lactobacillus buchneri 11 ~ 13.
4. a kind of preparation method for naturally moistening Anti-bacterium hand cream according to claim 1, which is characterized in that including following step
Suddenly：
（1）Cortex Magnoliae Officinalis, eupatorium, Pogostemon cablin, Poria cocos and cape jasmine are mixed, 200 ~ 240 mesh are crushed to, obtains traditional Chinese medicine powder, traditional Chinese medicine powder is added
The deionized water of 5 ~ 7 times of amounts of weight, steams 40 ~ 60 minutes in 124 ~ 128 DEG C, takes out, and it is original 1/6 ~ 1/ to decoct to volume
5, obtain decocting for Chinese herbal medicine liquid；
（2）Rice is crushed to 60 ~ 80 mesh, obtains rice flour, deionized water is added into rice flour, it is 45 ~ 50% to adjust water content, leaching
Bubble 3 ~ 4 hours accesses lactic acid bacteria, is uniformly mixed, and ferments 10 ~ 12 hours in 41 ~ 43 DEG C, obtains one time fermentation material；
（3）It is 0 ~ 6% that one time fermentation material, which is freeze-dried to water content, and the deionized water of 1.2 ~ 1.6 times of amounts of rice flour weight is added,
It is uniformly mixed, continues fermentation 2 ~ 3 days in 30 ~ 32 DEG C, obtain secondary fermentation material；
（4）Decocting for Chinese herbal medicine liquid is added into secondary fermentation material, is uniformly mixed, ferments 2 ~ 3 days in 32 ~ 34 DEG C, obtains fermentation material three times；
（5）Chinese yam is cleaned, is beaten, obtains Chinese yam pulp, fermentation material three times is added in Chinese yam pulp and Saccharomyces cerevisiae, is uniformly mixed, in
24 ~ 26 DEG C of ferment at constant temperature 24 ~ 36 hours, freeze-drying to water content are 45 ~ 50%, are centrifuged 13 ~ 15 minutes in 4000 revs/min,
Except precipitation, through two-period form homogeneous, obtains and naturally moisten Anti-bacterium hand cream；
（6）Packaging, radio sterilization are examined, and are obtained and are naturally moistened Anti-bacterium hand cream finished product.
5. naturally moistening the preparation method of Anti-bacterium hand cream according to claim 4, which is characterized in that the step（5）'s
Two sections of homogeneous, homogenizing temperature be 41 ~ 43 DEG C, first segment homogenization pressure be 27.4 ~ 28.9MPa, second segment homogenization pressure be 15.2 ~
16.6MPa。
6. naturally moistening the preparation method of Anti-bacterium hand cream according to claim 4, which is characterized in that the step（6）'s
Radio sterilization, dose of radiation are 34.6 ~ 36.3kGy.
7. a kind of application method of any one of claim 1 ~ 6 natural moist Anti-bacterium hand cream, which is characterized in that be suitable for
Baby and pregnant woman, wash one's hands or desirable appropriate naturally moist Anti-bacterium hand cream of not washing one's hands is applied on hand skin, are massaged into suction
It receives.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810756469.6A CN108653061A (en) | 2018-07-11 | 2018-07-11 | A kind of naturally moist Anti-bacterium hand cream |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106619373A (en) * | 2016-12-19 | 2017-05-10 | 陈增光 | Garlicin hand cream |
| CN107441026A (en) * | 2017-09-12 | 2017-12-08 | 陈德兴 | Replenishing water and preserving moisture hand lotion and preparation method thereof |
-
2018
- 2018-07-11 CN CN201810756469.6A patent/CN108653061A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106619373A (en) * | 2016-12-19 | 2017-05-10 | 陈增光 | Garlicin hand cream |
| CN107441026A (en) * | 2017-09-12 | 2017-12-08 | 陈德兴 | Replenishing water and preserving moisture hand lotion and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 王建新: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
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