CN108553370A - A kind of facial cleanser and preparation method thereof with acne-removing - Google Patents

A kind of facial cleanser and preparation method thereof with acne-removing Download PDF

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Publication number
CN108553370A
CN108553370A CN201810623554.5A CN201810623554A CN108553370A CN 108553370 A CN108553370 A CN 108553370A CN 201810623554 A CN201810623554 A CN 201810623554A CN 108553370 A CN108553370 A CN 108553370A
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Prior art keywords
acne
parts
facial cleanser
phases
hours
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CN201810623554.5A
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Chinese (zh)
Inventor
吴闯
田甜
佟洪波
柳青
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Liaoning Shihua University
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Liaoning Shihua University
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Priority to CN201810623554.5A priority Critical patent/CN108553370A/en
Publication of CN108553370A publication Critical patent/CN108553370A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85Polyesters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of facial cleanser and preparation method thereof with acne-removing, raw material includes the capsule leaves of pulse plants, thatch lamb's-quarters root, cordate houttuynia, Prunella vulgaris, honeysuckle, the different hexadecanol ester of 18 acyl of stearic acid, 10 dipalmitate of polyglycereol, xanthans, Phenoxyethanol and deionized water.The present invention inhibits acne inflammatory reaction, while going deep into hair follicle, strong disinfecting by adding effective ingredients in plant in facial cleanser.Skin surface grease can be effectively dispelled, clogging of pores is prevented, inhibits follicular infection, is diminished inflammation red and swollen caused by reaction, mild non-stimulated, bright and clean comfortable using rear face skin, long-time service has remarkable result to preventing and eliminating acne.

Description

A kind of facial cleanser and preparation method thereof with acne-removing
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of facial cleanser and preparation method thereof with acne-removing.
Background technology
Facial cleanser is a kind of common skin of face detergent, not only to skin surface attachment sebum, cuticula chip, The skin physiologies such as sweat metabolite and dust, microorganism, cosmetics residue have cleaning action, wherein that adds is certain Functional component also has the effects that nti-freckle smoothing wrinkle, moisturizes the skin.With the continuous improvement of living standards, people increasingly pay attention to day Change the feature of environmental protection, safety and the natural sex of articles for use.Increasingly with product made of Chinese herbal medicine and active ingredients in natural plants Mostly attract attention.If the plant extracts with acne-removing is added in facial cleanser, facial cleanser is while cleaning, also It can achieve the effect that anti-acne, anti-acne, more general anti-acne externally applied drug use more convenient.
Invention content
The technical problem to be solved in the present invention provides a kind of facial cleanser with acne-removing, effective by plant therein Ingredient, while cleaning skin of face, the effect of reaching anti-acne, anti-acne.
The technical solution adopted by the present invention is:
It is raw materials used to include by weight:
9 parts of Prunella vulgaris, 6 parts of honeysuckle, 7 parts of the capsule leaves of pulse plants, 7 parts of thatch lamb's-quarters root, 3 parts of cordate houttuynia, the different hexadecanol ester of 18 acyl of stearic acid 3 Part, 5 parts of Natrulon H-10 dipalmitate, 0.6 part of xanthans, 1 part of Phenoxyethanol, deionized water is to 100 parts.
The preparation method of the facial cleanser with acne-removing is as follows:
(1)Take the capsule leaves of pulse plants and thatch lamb's-quarters root crude drug to be ground into coarse powder, add 10 times amount 75% ethyl alcohol, heating water bath refluxing extraction 2 hours, Filtering, filter residue add 8 times of 75% ethyl alcohol of amount to continue refluxing extraction 2 hours, filtering, merging filtrate, filtrate decompression concentration, concentrate spray Mist is dried, and component A is obtained;
(2)Add 12 times of amount water to decoct twice by weight ratio Prunella vulgaris, honeysuckle, cordate houttuynia, 2 hours every time, merges twice Decoction liquor filters, and is concentrated under reduced pressure, and concentrate spray drying obtains component B;
(3)Component A, the different hexadecanol ester of 18 acyl of stearic acid and Natrulon H-10 dipalmitate are mixed as A phases and put into oil phase Pot is heated to 80 DEG C, and stirring is completely dissolved rear heat preservation for standby use;
(4)Water phase pot is added in deionized water, first component B and xanthan gum powder are sufficiently mixed, are then slowly added into water, 90 Rev/min stirring, adds stopping stirring, impregnates and then proceed to be slowly stirred for 3 hours, 30 revs/min, until xanthans is fully molten Solution, as B phases, is warming up to 80 DEG C of heat preservations;
(5)B phases are first pumped into emulsification pot, 45 revs/min of mixing speed, then A phases are pumped into, are stirred 30 minutes, temperature is maintained at 80 DEG C, homogeneous 3 minutes;
(6)It is cooled to room temperature, Phenoxyethanol is added, 30 revs/min are stirred 5 minutes, and discharging is vacuumized.
Prunella vulgaris clearing liver-fire in the present invention, solves strongly fragrant dissipating bind, subdhing swelling and detoxicating;Honeysuckle dispelling wind-heat is apt to removing summer-heat blood poison, It contains the detumescence of the pharmacological components Anhydroalkannin such as chlorogenic acid, cyanidenon glycosides;Cordate houttuynia energy is clearing heat and detoxicating, sore, institute are treated in detumescence Also there is notable anti-inflammatory effect containing flavone compounds such as Quercetin, quercitrin and Isoquercitrins, inflammation early stage can be significantly inhibited Capillary is hyperfunction;The capsule leaves of pulse plants is clearing heat and detoxicating, controls furunculosis carbuncle swells, nameless sores or boils;Thatch lamb's-quarters root can restrain analgesic.Emollient stearic acid ten The different hexadecanol ester of eight acyls is felt after providing dry and comfortable initial use feeling and smooth use.These components matchings can effectively dispel skin Skin surface grease prevents clogging of pores, inhibits follicular infection, diminishes inflammation red and swollen caused by reaction, can effectively inhibit to cause Cuo The many factors of sore, while the acne occurred can be made to eliminate rapidly, it is mild non-stimulated, it is used for a long time to preventing and eliminating acne There is remarkable result.
Specific implementation mode
Illustrate embodiments of the present invention with reference to embodiment.
Embodiment 1
It is raw materials used to include by weight:
Prunella vulgaris 900g, honeysuckle 600g, capsule leaves of pulse plants 700g, thatch lamb's-quarters root 700g, cordate houttuynia 300g, the different hexadecanol of 18 acyl of stearic acid Ester 300g, Natrulon H-10 dipalmitate 500g, xanthans 60g, Phenoxyethanol 100g, deionized water to 10kg.
The preparation method of the facial cleanser with acne-removing is as follows:
(1)It takes the capsule leaves of pulse plants and thatch lamb's-quarters root crude drug to be ground into coarse powder, adds 14kg75% ethyl alcohol, heating water bath refluxing extraction 2 hours, mistake Filter, filter residue add 11.2kg75% ethyl alcohol to continue refluxing extraction 2 hours, filtering, merging filtrate, filtrate decompression concentration, concentrate spraying It is dry, obtain component A;
(2)Add 21.6kg water to decoct twice by weight ratio Prunella vulgaris, honeysuckle, cordate houttuynia, 2 hours every time, merges twice Decoction liquor filters, and is concentrated under reduced pressure, and concentrate spray drying obtains component B;
(3)Component A, the different hexadecanol ester of 18 acyl of stearic acid and Natrulon H-10 dipalmitate are mixed as A phases and put into oil phase Pot is heated to 80 DEG C, and stirring is completely dissolved rear heat preservation for standby use;
(4)Water phase pot is added in deionized water, first component B and xanthan gum powder are sufficiently mixed, are then slowly added into water, 90 Rev/min stirring, adds stopping stirring, impregnates and then proceed to be slowly stirred for 3 hours, 30 revs/min, until xanthans is fully molten Solution, as B phases, is warming up to 80 DEG C of heat preservations;
(5)B phases are first pumped into emulsification pot, 45 revs/min of mixing speed, then A phases are pumped into, are stirred 30 minutes, temperature is maintained at 80 DEG C, homogeneous 3 minutes;
(6)It is cooled to room temperature, Phenoxyethanol is added, 30 revs/min are stirred 5 minutes, and discharging is vacuumized.
Measure of merit:
Selecting has face acnes tester 120 for 18-22 years old, and men and women is fifty-fifty.Wherein 60 are used as experimental group that the present invention is used to wash one's face Milk, 30 1 use the commercially available common common facial cleanser of brand as a control group, and 30 2 have anti-acne work(using commercially available as a control group The facial cleanser of energy, each group men and women's mean allocation, all testers once in the morning and once at night clean face in two months with facial cleanser.Evaluation Standard:In vain:Existing acne and new hair acne conditions are without any improvement than before;Effectively:Existing acne to dispel speed apparent Accelerate or new hair acne significantly reduces;It is effective:Existing acne is dispelled, without new hair acne.
Test result shows the present invention for preventing and eliminating acne significant effect.

Claims (1)

1. a kind of facial cleanser with acne-removing, it is characterised in that:It is raw materials used to include by weight:
9 parts of Prunella vulgaris, 6 parts of honeysuckle, 7 parts of the capsule leaves of pulse plants, 7 parts of thatch lamb's-quarters root, 3 parts of cordate houttuynia, the different hexadecanol ester of 18 acyl of stearic acid 3 Part, 5 parts of Natrulon H-10 dipalmitate, 0.6 part of xanthans, 1 part of Phenoxyethanol, deionized water is to 100 parts;
The preparation method of the facial cleanser with acne-removing is as follows:
(1)Take the capsule leaves of pulse plants and thatch lamb's-quarters root crude drug to be ground into coarse powder, add 10 times amount 75% ethyl alcohol, heating water bath refluxing extraction 2 hours, Filtering, filter residue add 8 times of 75% ethyl alcohol of amount to continue refluxing extraction 2 hours, filtering, merging filtrate, filtrate decompression concentration, concentrate spray Mist is dried, and component A is obtained;
(2)Add 12 times of amount water to decoct twice by weight ratio Prunella vulgaris, honeysuckle, cordate houttuynia, 2 hours every time, merges twice Decoction liquor filters, and is concentrated under reduced pressure, and concentrate spray drying obtains component B.
(3)Component A, the different hexadecanol ester of 18 acyl of stearic acid and Natrulon H-10 dipalmitate are mixed as A phases and put into oil phase Pot is heated to 80 DEG C, and stirring is completely dissolved rear heat preservation for standby use;
(4)Water phase pot is added in deionized water, first component B and xanthan gum powder are sufficiently mixed, are then slowly added into water, 90 Rev/min stirring, adds stopping stirring, impregnates and then proceed to be slowly stirred for 3 hours, 30 revs/min, until xanthans is fully molten Solution, as B phases, is warming up to 80 DEG C of heat preservations;
(5)B phases are first pumped into emulsification pot, 45 revs/min of mixing speed, then A phases are pumped into, are stirred 30 minutes, temperature is maintained at 80 DEG C, homogeneous 3 minutes;
(6)It is cooled to room temperature, Phenoxyethanol is added, 30 revs/min are stirred 5 minutes, and discharging is vacuumized.
CN201810623554.5A 2018-06-16 2018-06-16 A kind of facial cleanser and preparation method thereof with acne-removing Pending CN108553370A (en)

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CN201810623554.5A CN108553370A (en) 2018-06-16 2018-06-16 A kind of facial cleanser and preparation method thereof with acne-removing

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112494391A (en) * 2020-12-22 2021-03-16 上海浙星新型材料科技有限公司 Green and safe acne-removing composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494758A (en) * 2013-09-18 2014-01-08 王玉琴 Acne-removing facial cleanser
CN104434685A (en) * 2014-12-10 2015-03-25 唯美度科技(北京)有限公司 Light facial cleanser and preparation method of light facial cleanser
CN104958543A (en) * 2015-06-08 2015-10-07 王志顺 Traditional Chinese medicinal acne removing and skin cleansing lotion, and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494758A (en) * 2013-09-18 2014-01-08 王玉琴 Acne-removing facial cleanser
CN104434685A (en) * 2014-12-10 2015-03-25 唯美度科技(北京)有限公司 Light facial cleanser and preparation method of light facial cleanser
CN104958543A (en) * 2015-06-08 2015-10-07 王志顺 Traditional Chinese medicinal acne removing and skin cleansing lotion, and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
南京中医药大学: "《中药大辞典》", 31 March 2006, 上海科技出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112494391A (en) * 2020-12-22 2021-03-16 上海浙星新型材料科技有限公司 Green and safe acne-removing composition

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