CN104434685A - Light facial cleanser and preparation method of light facial cleanser - Google Patents

Light facial cleanser and preparation method of light facial cleanser Download PDF

Info

Publication number
CN104434685A
CN104434685A CN201410758454.5A CN201410758454A CN104434685A CN 104434685 A CN104434685 A CN 104434685A CN 201410758454 A CN201410758454 A CN 201410758454A CN 104434685 A CN104434685 A CN 104434685A
Authority
CN
China
Prior art keywords
extract
cleansing milk
facial cleanser
add
radix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410758454.5A
Other languages
Chinese (zh)
Inventor
陈�光
孙宇南
张晓茹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AESTHETIC TECHNOLOGY (BEIJING) Co Ltd
Original Assignee
AESTHETIC TECHNOLOGY (BEIJING) Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AESTHETIC TECHNOLOGY (BEIJING) Co Ltd filed Critical AESTHETIC TECHNOLOGY (BEIJING) Co Ltd
Priority to CN201410758454.5A priority Critical patent/CN104434685A/en
Publication of CN104434685A publication Critical patent/CN104434685A/en
Pending legal-status Critical Current

Links

Landscapes

  • Cosmetics (AREA)

Abstract

The invention discloses a light facial cleanser and a preparation method of the light facial cleanser. The light facial cleanser is prepared from the following components in part by weight: 0.01-6 parts of Chinese herbal medicine composition, 1-34 parts of oily component, 0.03-5 parts of a neutralizing agent, 1-15 parts of a surface active agent, 0.1-6 parts of polyol, and deionized water which is added until the total amount is 100 parts, wherein active ingredients in the Chinese herbal medicines can be dissolved and released well due to the compatibility of the Chinese herbal medicine composition and assistants, propionibacterium acnes can be effectively inhibited, and the light facial cleanser has the efficacies of preventing and relieving acne, controlling oil releasing, relieving itching and the like; and besides, the light facial cleanser has good usability and appropriate viscosity, can be used for thoroughly cleaning the skin, enables the skin to be smooth, delicate, fair and glossy, and is suitable for people at different ages; and furthermore, when the light facial cleanser is used, the skin sensation is good, and the light facial cleanser has a non-greasy effect and air permeability and is light.

Description

The cleansing milk that a kind of quality is slim and graceful and preparation thereof
Technical field
The present invention relates to daily cosmetics, be specifically related to the cleansing milk that a kind of quality is slim and graceful, also relate to the preparation of this cleansing milk.
Background technology
Comedo, acne, skin sore are medically referred to as acne, be common a kind of cortex gland chronic disease, acne is mainly in adolescence (16-30 about year), and its origin cause of formation is that hebetic hormone stimulates, smegma is vigorous, cause clogging of pores to form micropowder thorn, and micropowder thorn blocking pore bring out inflammation, causes pustule, the series of symptoms such as cyst, and after acne is eliminated, can grow again after a period of time, form the situation of recurrent exerbation.
Why so obstinate is acne, always recurrent exerbation? everything comes from the arch-criminal-propionibacterium acnes of acne in fact.Propionibacterium acnes (Propionibacterium acnes), also claims Propiobacterium, Propionibacterium, is the main bacteria causing comedo.The no pathogenicity of Propiobacterium own, everyone hairy cyst has this bacterium, and it take sebum as food, produces fatty acid.Under normal circumstances, Propiobacterium can maintain cuticular weak acid environment, keeps out the invasion of external pathogen.And if bacillus excessive multiplication causes inflammatory lesion with regard to Diazolidinyl Urea, and occur red and swollen, pruritus, the skin problems such as pimple.
Reach maturity along with teen-age, smegma function also obviously increases, and sebum contains the composition secretions such as more fatty acid, and become the hotbed of Propiobacterium Growth and reproduction, this also just becomes acne in adolescence main cause repeatedly.And the product for resolving poxes in existing market, generally adopt medicine or Antibiotics kill propionibacterium acnes, can alleviate and treat comedo, but propionibacterium acnes has strong Drug resistance, traditional medicine is after particularly antibiotic enters skin, propionibacterium acnes can produce rapidly resistance bacterial strain, resists medicine, and this kind of product for resolving poxes cannot fundamentally control and treat comedo.
, often there is greasy, airtight, salubrious not problem in existing cleansing milk.
Prior art is compared, Chinese herbal medicine extract and additive compatibility in the present invention, makes the active component in Chinese herbal medicine dissolve better and to discharge, effectively suppresses propionibacterium acnes, has good prevention and easing whelk, control oil and the effect such as antipruritic.And the usability of cleansing milk of the present invention is very good, viscosity is suitable, and skin is clean more thorough, uses careful, the delicate gloss of rear skin slip, is applicable to each age group and uses.When cleansing milk of the present invention uses in addition, dermal sensation is good, non-greasy, good permeability, and quality is slim and graceful.
Summary of the invention
The first object of the present invention is to provide the slim and graceful cleansing milk of a kind of quality, non-greasy, good permeability during use, and effectively can remove the growth of comedo, suppression propionibacterium acnes.
The cleansing milk that quality of the present invention is slim and graceful, be made up of following each component by weight:
Described herbal composite is Flos Caryophylli extract, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Radix Scutellariae extract, Radix Salviae Miltiorrhizae extract, Radix Et Rhizoma Rhei extract, Cortex Moutan extract, Radix Gentianae extract, in Aloe extract at least three kinds.
The cleansing milk that quality of the present invention is slim and graceful, wherein, described oily components is mineral oil, at least one in isopropyl myristate, isopropyl palmitate, caprylic/capric triglyceride and lanoline, hexadecanol, octadecanol, preferred isopropyl myristate and/or isopropyl palmitate.
The cleansing milk that quality of the present invention is slim and graceful, wherein, described nertralizer is sodium hydroxide and/or potassium hydroxide.
The cleansing milk that quality of the present invention is slim and graceful, wherein, described surfactant is fatty glyceride, span, Salcare SC91, Tinovis ADM, Sepigel 501, at least one in glyceryl monostearate, tween 20, tween 80, polyoxyethylene (30) dimerization hydroxy stearic acid ester, at least one in preferred glyceryl monostearate, tween 20, tween 80, at least one in preferred glyceryl monostearate, tween 20, polyoxyethylene (30) dimerization hydroxy stearic acid ester.
The cleansing milk that quality of the present invention is slim and graceful, wherein, described polyhydric alcohol is glycerol and/or propylene glycol.
The cleansing milk that quality of the present invention is slim and graceful, as preferred scheme, be made up of following each component by weight:
It is that 2-4:0.5-2:1-3 forms that described herbal composite is closed by weight by Flos Caryophylli extract, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract and Radix Gentianae extract.
As preferred scheme, be made up of following each component by weight:
Described herbal composite is by Flos Caryophylli extract, and the combination of Folium eucalypti globueli (Eucalyptus globulus Labill.) extract and Radix Gentianae extract three kinds, the weight relationships of three kinds of extracts is 3:1:2.
The cleansing milk that quality of the present invention is slim and graceful, described Chinese herbal medicine extract is prepared preferably by following preparation method:
Prepared by Flos Caryophylli extract: first dry after Flos Caryophylli surface clean, dry in 50 DEG C of drying baker again, then smash into 150-200 object powder to pieces with dismembyator, take powder and be placed in container, add the analytical pure ethanol of 6-10 times amount, keep 65 DEG C of constant temperature, and constantly stir 3 hours, then use filter paper filtering, the analytical pure ethanol that residue is placed in 6-10 times amount is brought up again, is collected filtrate, merging filtrate is concentrated in freeze dryer, obtains Flos Caryophylli extract;
Prepared by Folium eucalypti globueli (Eucalyptus globulus Labill.) extract: get fresh blade, the dirt removing surface is placed in 45 DEG C of drying baker dries 5 hours, smash powdered to pieces with dismembyator to sieve, get the powder after sieving and be placed in container, by 75% (V/V) soak with ethanol of 2-3 times amount, after being placed in shaking table overnight shaking, cross leaching supernatant, 75% (V/V) ethanol that residue is placed in 2-3 times amount is brought up again, merging filtrate, be placed in after refrigerator and cooled is frozen and concentrate in freeze dryer, obtain Folium eucalypti globueli (Eucalyptus globulus Labill.) extract;
Prepared by Radix Scutellariae extract: get dry scutellariae,radix, add the soak by water of 2-3 times amount, leave standstill, be concentrated into appropriate, get concentrated hydrochloric acid and regulate pH to 1.0-2.0, after 80 DEG C of insulations filter, by alkali liquor adjust ph to 7.0, add equal volume amounts ethanol, stirring makes to dissolve, filter precipitation, by filtrate lyophilization, obtain Radix Scutellariae extract;
Prepared by Radix Salviae Miltiorrhizae extract: Radix Salviae Miltiorrhizae crushed after being dried is become coarse powder, 75%-90% (V/V) alcohol heating reflux adding 6-10 times amount extracts, filters three times, each extraction 3-5 hour, merging filtrate, decompression recycling ethanol to be condensed into relative density be 1.30 ~ 1.35 (60 DEG C-70 DEG C) thick paste, colourless to washing liquid by hot water wash, 80 DEG C-90 DEG C dry, pulverize into fine powder and get final product;
Prepared by Radix Et Rhizoma Rhei extract: by Radix Et Rhizoma Rhei crushed after being dried, then use 80%-95% (V/V) the alcohol reflux 3-5 hour of 6-10 times amount, filters, concentrates filtrate to extractum shape and get final product;
Prepared by Cortex Moutan extract: by the soak by water half an hour of Cortex Moutan medical material by 2-3 times amount, add the Nacl accounting for Cortex Moutan quality 10%-25%, agitation and filtration impurity, refrigerated overnight, lyophilization and get final product;
Prepared by Radix Gentianae extract: by the distilled water immersion 2h of Radix Gentianae by 10-15 times amount, then decoct 2 times, decoct 0.5h at every turn, and after merging filtrate is concentrated, filter freezing is drying to obtain;
Prepared by Aloe extract: separated by fresh aloe crust, and taken out by Aloe gel, with high speed disintegrator by leaf skin tissue mashing, high speed centrifugation carries out precipitation process, filters, and Aloe gel merging obtains the pure stock solution of Aloe, and freeze concentration is drying to obtain.
Chinese medicine extract described in the present invention, by corresponding preparation method dry or concentrated after, in the extract of gained, solid content is not less than 95%.
Present invention also offers the preparation method of the slim and graceful cleansing milk of described quality, concrete steps are as follows:
1) by retort, first add a small amount of of the deionized water taken by proportional quantity, rear slowly add proportional quantity oily components and polyhydric alcohol be heated with stirring to 55-65 DEG C;
2) in step 1) add the nertralizer saponification of proportional quantity in the mixture that obtains;
3) in step 2) mixture that obtains adds the surfactant of proportional quantity, and add residue deionized water, after fully stirring, cool to 40-45 DEG C;
4) in step 3) add the herbal composite of proportional quantity in the mixture that obtains, after stirring, froth breaking cooling, obtains the cleansing milk that described quality is slim and graceful.
The preparation method of the cleansing milk that quality of the present invention is slim and graceful, wherein, deionized water be on a small quantity in step (1), describedly refers to the amount that oily components and polyhydric alcohol just dissolve by deionized water on a small quantity.
Detailed description of the invention
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.
Prepared by Flos Caryophylli extract: first dry after Flos Caryophylli surface clean, dry in 50 DEG C of drying baker again, then smash into 150-200 object powder to pieces with dismembyator, take powder and be placed in container, add the analytical pure ethanol of 6-10 times amount, keep 65 DEG C of constant temperature, and constantly stir 3 hours, then use filter paper filtering, the analytical pure ethanol that residue is placed in 6-10 times amount is brought up again, is collected filtrate, merging filtrate is concentrated in freeze dryer, obtains Flos Caryophylli extract for subsequent use;
Prepared by Folium eucalypti globueli (Eucalyptus globulus Labill.) extract: get fresh blade, the dirt removing surface is placed in 45 DEG C of drying baker dries 5 hours, smash powdered to pieces with dismembyator to sieve, get the powder after sieving and be placed in container, by 75% (V/V) soak with ethanol of 2-3 times amount, after being placed in shaking table overnight shaking, cross leaching supernatant, 75% (V/V) ethanol that residue is placed in 2-3 times amount is brought up again, merging filtrate, be placed in after refrigerator and cooled is frozen and concentrate in freeze dryer, obtain Folium eucalypti globueli (Eucalyptus globulus Labill.) extract for subsequent use;
Prepared by Radix Scutellariae extract: get dry scutellariae,radix, add the soak by water of 2-3 times amount, leave standstill, be concentrated into appropriate, get concentrated hydrochloric acid and regulate pH to 1.0-2.0, after 80 DEG C of insulations filter, by alkali liquor adjust ph to 7.0, add equal volume amounts ethanol, stirring makes to dissolve, filter precipitation, by filtrate lyophilization, obtain Radix Scutellariae extract for subsequent use;
Prepared by Radix Salviae Miltiorrhizae extract: Radix Salviae Miltiorrhizae crushed after being dried is become coarse powder, 75%-90% (V/V) alcohol heating reflux adding 6-10 times amount extracts, filters three times, each extraction 3-5 hour, merging filtrate, decompression recycling ethanol to be condensed into relative density be 1.30 ~ 1.35 (60 DEG C-70 DEG C) thick paste, colourless to washing liquid by hot water wash, 80 DEG C-90 DEG C to dry, pulverize into fine powder for subsequent use;
Prepared by Radix Et Rhizoma Rhei extract: by Radix Et Rhizoma Rhei crushed after being dried, then use 80%-95% (V/V) the alcohol reflux 3-5 hour of 6-10 times amount, filters, concentrates filtrate to extractum shape for subsequent use;
Prepared by Cortex Moutan extract: by the soak by water half an hour of Cortex Moutan medical material by 2-3 times amount, add the Nacl accounting for Cortex Moutan quality 10%-25%, agitation and filtration impurity, refrigerated overnight, lyophilization is for subsequent use;
Prepared by Radix Gentianae extract: by the distilled water immersion 2h of Radix Gentianae by 10-15 times amount, then decoct 2 times, decoct 0.5h at every turn, after merging filtrate is concentrated, and filter freezing drying for standby;
Prepared by Aloe extract: separated by fresh aloe crust, and taken out by Aloe gel, with high speed disintegrator by leaf skin tissue mashing, high speed centrifugation carries out precipitation process, filters, and Aloe gel merging obtains the pure stock solution of Aloe, freeze concentration drying for standby.
Embodiment 1: the cleansing milk that quality is slim and graceful
The cleansing milk that the present embodiment quality is slim and graceful, each component following by weight is prepared from: Flos Caryophylli extract 1.5g, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 0.5g, Radix Gentianae extract 1g, potassium hydroxide 0.1g, isopropyl palmitate 25g, propylene glycol 3g, glyceryl monostearate 13g, deionized water adds to 100g.
The preparation method of the cleansing milk that the present embodiment quality is slim and graceful, concrete steps are as follows:
1) in retort, first add a small amount of deionized water, slowly add isopropyl palmitate and propylene glycol is heated with stirring to 60 DEG C afterwards;
2) in step 1) add potassium hydroxide saponification in the mixture that obtains;
3) in step 2) add glyceryl monostearate in the mixture that obtains, add remaining deionized water, after fully stirring, cool to 43 DEG C;
4) in step 3) add Chinese medicine extract, i.e. Radix Gentianae extract, Flos Caryophylli extract and Folium eucalypti globueli (Eucalyptus globulus Labill.) extract in the mixture that obtains, froth breaking cooling after stirring, namely obtains a kind of cleansing milk slim and graceful containing quality.
Embodiment 2: the cleansing milk that quality is slim and graceful
The cleansing milk that the present embodiment quality is slim and graceful, each component following by weight is prepared from: Flos Caryophylli extract 1.14g, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 0.29g, Radix Gentianae extract 0.57g, potassium hydroxide 1g, isopropyl palmitate 20g, propylene glycol 2g, glyceryl monostearate 12g, deionized water adds to 100g.
The preparation method of the cleansing milk that the present embodiment quality is slim and graceful is identical with embodiment 1.
Embodiment 3: the cleansing milk that quality is slim and graceful
The cleansing milk that the present embodiment quality is slim and graceful, each component following by weight is prepared from: Flos Caryophylli extract 1.78g, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 0.89g, Radix Gentianae extract 1.33g, potassium hydroxide 0.05g, isopropyl palmitate 30g, propylene glycol 4g, glyceryl monostearate 14g, deionized water adds to 100g.
The preparation method of the cleansing milk that the present embodiment quality is slim and graceful is identical with embodiment 1.
Embodiment 4: the cleansing milk that quality is slim and graceful
The cleansing milk that the present embodiment quality is slim and graceful, the each component following by weight is prepared from: Flos Caryophylli extract 1.14g, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract 0.29g, Radix Gentianae extract 0.57g, sodium hydroxide 1g, isopropyl myristate 20g, glycerol 2g, polyoxyethylene (30) dimerization hydroxy stearic acid ester 4g, tween 20 8g, deionized water adds to 100g.
The preparation method of the cleansing milk that the present embodiment quality is slim and graceful is identical with embodiment 1.
Embodiment 5: the cleansing milk that quality is slim and graceful
The cleansing milk that the present embodiment quality is slim and graceful, each component following by weight is prepared from: Radix Scutellariae extract 2g, Radix Salviae Miltiorrhizae extract 1g, Cortex Moutan extract 1g, potassium hydroxide 0.05g, isopropyl palmitate 30g, propylene glycol 4g, glyceryl monostearate 14g, deionized water adds to 100g.
The preparation method of the cleansing milk that the present embodiment quality is slim and graceful is identical with embodiment 1.
Embodiment 6: the cleansing milk that quality is slim and graceful
The cleansing milk that the present embodiment quality is slim and graceful, each component following by weight is prepared from: Aloe extract 0.005g, Radix Et Rhizoma Rhei extract 0.003g, Cortex Moutan extract 0.002g, sodium hydroxide 0.03g, mineral oil 1g, propylene glycol 0.1g, fatty glyceride 1g, deionized water adds to 100g.
The preparation method of the cleansing milk that the present embodiment quality is slim and graceful is identical with embodiment 1.
Embodiment 7: the cleansing milk that quality is slim and graceful
The cleansing milk that the present embodiment quality is slim and graceful, each component following by weight is prepared from: Radix Scutellariae extract 3g, Radix Salviae Miltiorrhizae extract 1g, Aloe extract 2g, potassium hydroxide 5g, lanoline 34g, and propylene glycol 6g, Sepigel 50115g, deionized water adds to 100g.
The preparation method of the cleansing milk that the present embodiment quality is slim and graceful is identical with embodiment 1.
Experimental example 1: the clinical experiment of anti-acne effect
1, the preparation of sample liquid:
Sample 1-5 is respectively the sample prepared by embodiment of the present invention 1-5.
Reference substance 1-5: the composition of reference example 2 and preparation method, wherein:
Reference substance 1: delete Folium eucalypti globueli (Eucalyptus globulus Labill.) extract and Radix Gentianae extract, Flos Caryophylli extract is 2g;
Reference substance 2: delete Folium eucalypti globueli (Eucalyptus globulus Labill.) extract and Flos Caryophylli extract, Radix Gentianae extract is 2g;
Reference substance 3: delete Flos Caryophylli extract and Radix Gentianae extract, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract is 2g;
Reference substance 4: delete Flos Caryophylli extract, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract and Radix Gentianae extract, change Radix Zanthoxyli extract 1.14g, Rhizoma Coptidis extract 0.29g, camomile extract 0.57g into, remaining composition is identical with embodiment 2 with weight;
Reference substance 5: the component of Chinese medicine extract is identical with embodiment 2 with weight, and all the other components change the auxiliary agent used in patent No. CN102579309 into: single alkyl phosphonic acid potassium salt 30g, cocamido propyl betaine 1g, coconut oil fat acid alcohol single ethanol amide 8g, glycerol 3g, PEG-4000 2g, stearic acid diethylene glycol dilaurate 1g, menthol 0.6g, tetrasodium ethylenediamine tetraacetate 0.01g, Macrogol 600 two stearate 0.5g, acrylate copolymer 1g, essence 0.2g, KF88 0.02g and deionized water 50.67g.
2, object of study
Choose 210 volunteers, age 15-35 year, average 21 years old, each 105 people of men and women.All there are pimple and acne in face, conscious slight pruritus or pain, repeatedly difficult.Be divided into 10 experimental grouies at random, often organize 21 people.
3, experimental technique
Experimental group 1-5 uses sample 1-5, and experimental group 6-10 uses reference substance 1-5.
Using method: use every day experiment product to wash one's face 2 times 4 weeks is a course for the treatment of, uses a course for the treatment of continuously.
Evaluation criterion: (1) obviously improves: clinical symptom disappearance, erythra acne disappear; (2) alleviate: clinical symptom relief, erythra acne partial remission or disappearance; (3) invalid: clinical symptoms, erythra acne are without improvement.
Evaluation time is for using latter 1 week, 2 weeks, 3 weeks, 4 weeks.
4, experimental result
4.1 uses are after 1 week: in table 1.
Table 1: result of use statistics (%) after using 1 week
Table 1 result shows: compared with reference substance 1-5, and use the obvious improvement rate of sample 1-5 and remission rate extremely remarkable, wherein the result of use of sample 1-3 is best, best with the result of use of sample 1.
4.2 uses are after 2 weeks: in table 2.
Table 2: statistical effect (%) after using 2 weeks
Table 2 result shows: compared with reference substance 1-5, and use the obvious improvement rate of sample 1-5 and remission rate highly significant, wherein the result of use of sample 1-3 is best, best with the result of use of sample 1.
4.3 uses are after 3 weeks: in table 3.
Table 3: statistical effect (%) after using 3 weeks
Table 3 result shows: compared with reference substance 1-5, and use the obvious improvement rate of sample 1-5 and remission rate significantly, wherein the result of use of sample 1-3 is best, best with the result of use of sample 1.
4.4 uses are after 4 weeks: in table 4.
Table 4: statistical effect (%) after using 4 weeks
Table 4 result shows: compared with reference substance 1-5, and use the obvious improvement rate of sample 1-5 and remission rate extremely remarkable, wherein the result of use of sample 1-3 is best, best with the result of use of sample 1.
In summary, sample 1-5 has obvious clinical effectiveness, and especially the effect of sample 1-3 is more remarkable, and when use is after 4 weeks, the obvious improvement rate of the clinical symptoms of volunteer reaches more than 80%, is best, reaches 90% with sample 1.There is good treatment erythra, anti-acne effect.
Experimental example 2: the fungistatic effect experiment of the cleansing milk that quality of the present invention is slim and graceful
1, experimental technique: the mensuration of antibacterial circle diameter size---filter paper enzyme
2, experimental principle:
Inoculating in the culture medium for examination strain, imposing quantitative test sample, utilizing the scattering and permeating effect of test sample in agar culture medium, after certain hour, sample permeates diffusion reaches certain limit.In the scope that Mlc reaches, the growth of indicator bacteria is just suppressed, produces an aseptic transparent region, becomes inhibition zone.Under certain condition with in certain limit, the diameter of inhibition zone and the logarithm of test sample concentration are in line functional relationship.Utilize this principle, the size of cleansing milk bacteriostasis can be compared.
3, preparation of samples is tested
Identical with reference substance 1-5 with the sample 1-5 in experimental example 1.Each test sample surveys 3 times, obtains average diameter.
4, the inhibition zone of extracorporeal bacteria inhibitor test the results are shown in Table 5.
Table 5: the average diameter of inhibition zone result (mm) of extracorporeal bacteria inhibitor test
Sample Sample 1 Sample 2 Sample 3 Sample 4 Sample 5
Propionibacterium acnes 31.62 29.31 27.65 24.63 25.78
Reference substance Reference substance 1 Reference substance 2 Reference substance 3 Reference substance 4 Reference substance 5
Propionibacterium acnes 19.23 19.65 19.01 16.01 24.02
The criterion of In Vitro Bacteriostasis qualitative results: it is insensitive that the diameter of inhibition zone is less than 8mm, and 8-13mm is less sensitive, and more than 19mm is extremely sensitive.
To sum up analyze known, the antibacterial sensitivity of the cleansing milk that quality of the present invention is slim and graceful is high, and fungistatic effect is remarkable.
Although above the present invention is described in detail with a general description of the specific embodiments, on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.

Claims (9)

1. the cleansing milk that quality is slim and graceful, is characterized in that: be made up of following each component by weight:
Described herbal composite is Flos Caryophylli extract, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract, Radix Scutellariae extract, Radix Salviae Miltiorrhizae extract, Radix Et Rhizoma Rhei extract, Cortex Moutan extract, Radix Gentianae extract, in Aloe extract at least three kinds.
2. cleansing milk according to claim 1, it is characterized in that: described oily components is at least one in mineral oil, isopropyl myristate, isopropyl palmitate, caprylic/capric triglyceride and lanoline, hexadecanol, octadecanol, preferred isopropyl myristate and/or isopropyl palmitate.
3. cleansing milk according to claim 1, is characterized in that: described nertralizer is sodium hydroxide and/or potassium hydroxide.
4. cleansing milk according to claim 1, it is characterized in that: described surfactant is at least one in fatty glyceride, span, Salcare SC91, Tinovis ADM, Sepigel 501, glyceryl monostearate, tween 20, tween 80, polyoxyethylene (30) dimerization hydroxy stearic acid ester, at least one in preferred glyceryl monostearate, tween 20, polyoxyethylene (30) dimerization hydroxy stearic acid ester.
5. cleansing milk according to claim 1, is characterized in that: described polyhydric alcohol is glycerol and/or propylene glycol.
6. cleansing milk according to any one of claim 1 to 5, is characterized in that: be made up of following each component by weight:
It is that 2-4:0.5-2:1-3 forms that described herbal composite is closed by weight by Flos Caryophylli extract, Folium eucalypti globueli (Eucalyptus globulus Labill.) extract and Radix Gentianae extract.
7. cleansing milk according to claim 6, is characterized in that: be made up of following each component by weight:
Described herbal composite is by Flos Caryophylli extract, and the combination of Folium eucalypti globueli (Eucalyptus globulus Labill.) extract and Radix Gentianae extract three kinds, the weight relationships of three kinds of extracts is 3:1:2.
8. cleansing milk according to claim 7, is characterized in that: described Chinese herbal medicine extract preparation method is as follows:
Prepared by Flos Caryophylli extract: first dry after Flos Caryophylli surface clean, dry in 50 DEG C of drying baker again, then smash into 150-200 object powder to pieces with dismembyator, take powder and be placed in container, add the analytical pure ethanol of 6-10 times amount, keep 65 DEG C of constant temperature, and constantly stir 3 hours, then use filter paper filtering, the analytical pure ethanol that residue is placed in 6-10 times amount is brought up again, is collected filtrate, merging filtrate is concentrated in freeze dryer, obtains Flos Caryophylli extract;
Prepared by Folium eucalypti globueli (Eucalyptus globulus Labill.) extract: get fresh blade, the dirt removing surface is placed in 45 DEG C of drying baker dries 5 hours, smash powdered to pieces with dismembyator to sieve, get the powder after sieving and be placed in container, by 75% soak with ethanol of 2-3 times amount, after being placed in shaking table overnight shaking, cross leaching supernatant, 75% ethanol that residue is placed in 2-3 times amount is brought up again, merging filtrate, be placed in after refrigerator and cooled is frozen and concentrate in freeze dryer, obtain Folium eucalypti globueli (Eucalyptus globulus Labill.) extract;
Prepared by Radix Gentianae extract: by the distilled water immersion 2h of Radix Gentianae by 10-15 times amount, then decoct 2 times, decoct 0.5h at every turn, and after merging filtrate is concentrated, filter freezing is drying to obtain.
9. the preparation method of cleansing milk according to any one of claim 1 to 8, is characterized in that: concrete steps are as follows:
(1) by retort, first add a small amount of of the deionized water taken by proportional quantity, rear slowly add proportional quantity oily components and polyhydric alcohol be heated with stirring to 55-65 DEG C;
(2) in step 1) add the nertralizer saponification of proportional quantity in the mixture that obtains;
(3) in step 2) mixture that obtains adds the surfactant of proportional quantity, and add residue deionized water, after fully stirring, cool to 40-45 DEG C;
(4) in step 3) add the herbal composite of proportional quantity in the mixture that obtains, after stirring, froth breaking cooling, obtains the cleansing milk that described quality is slim and graceful.
CN201410758454.5A 2014-12-10 2014-12-10 Light facial cleanser and preparation method of light facial cleanser Pending CN104434685A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410758454.5A CN104434685A (en) 2014-12-10 2014-12-10 Light facial cleanser and preparation method of light facial cleanser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410758454.5A CN104434685A (en) 2014-12-10 2014-12-10 Light facial cleanser and preparation method of light facial cleanser

Publications (1)

Publication Number Publication Date
CN104434685A true CN104434685A (en) 2015-03-25

Family

ID=52881956

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410758454.5A Pending CN104434685A (en) 2014-12-10 2014-12-10 Light facial cleanser and preparation method of light facial cleanser

Country Status (1)

Country Link
CN (1) CN104434685A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105125465A (en) * 2015-09-29 2015-12-09 青岛海之源智能技术有限公司 Freckle removing facial cleanser and preparing method thereof
CN105266148A (en) * 2015-08-27 2016-01-27 李宏 Life prolonging slice for elderly people
CN107441189A (en) * 2017-09-30 2017-12-08 张存龙 A kind of external medicine composition for treating acne
CN108553370A (en) * 2018-06-16 2018-09-21 辽宁石油化工大学 A kind of facial cleanser and preparation method thereof with acne-removing
CN111110579A (en) * 2020-02-12 2020-05-08 常德集智生物科技有限公司 Green antibacterial bactericidal facial cleanser
CN111529440A (en) * 2020-04-22 2020-08-14 重庆市中药研究院 Preparation method of acne-removing emulsion

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1436524A (en) * 2003-03-03 2003-08-20 杭州浙大力夫生物科技有限公司 Application of bamboo leaf general flavone as antisenility skin care factor in cosmetics
CN102068498A (en) * 2010-11-26 2011-05-25 新时代健康产业(集团)有限公司 Chinese medicinal composition with acne treatment and anti-inflammation effects, preparation and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1436524A (en) * 2003-03-03 2003-08-20 杭州浙大力夫生物科技有限公司 Application of bamboo leaf general flavone as antisenility skin care factor in cosmetics
CN102068498A (en) * 2010-11-26 2011-05-25 新时代健康产业(集团)有限公司 Chinese medicinal composition with acne treatment and anti-inflammation effects, preparation and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
夏明静等: "22种抗菌消炎中药有效成分对痤疮丙酸杆菌的抑制作用", 《中华皮肤科杂志》 *
武谦虎: "《美容中药一本通》", 31 October 2013, 中国医药科技出版社 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105266148A (en) * 2015-08-27 2016-01-27 李宏 Life prolonging slice for elderly people
CN105125465A (en) * 2015-09-29 2015-12-09 青岛海之源智能技术有限公司 Freckle removing facial cleanser and preparing method thereof
CN107441189A (en) * 2017-09-30 2017-12-08 张存龙 A kind of external medicine composition for treating acne
CN108553370A (en) * 2018-06-16 2018-09-21 辽宁石油化工大学 A kind of facial cleanser and preparation method thereof with acne-removing
CN111110579A (en) * 2020-02-12 2020-05-08 常德集智生物科技有限公司 Green antibacterial bactericidal facial cleanser
CN111529440A (en) * 2020-04-22 2020-08-14 重庆市中药研究院 Preparation method of acne-removing emulsion

Similar Documents

Publication Publication Date Title
CN104434685A (en) Light facial cleanser and preparation method of light facial cleanser
CN107007513B (en) External composition with blackhead removing and pore shrinking effects and skin cleaning mask
CN103735458B (en) A kind of skin antiallergic maintenance compositions
KR102001721B1 (en) Watery lotion skin care compositions and methods
CN105267092A (en) Plant extract and preparation method and application thereof
KR101764533B1 (en) Composition of toothpaste containing extract of euphorbia supina
CN102227208A (en) Drug or dermatological composition containing avocado peptide extract for treating and preventing pruritus
CN105327079A (en) Composition with repairing effect on mosquito bite and application thereof
KR102471043B1 (en) Functional cosmetic composition having simmondsia chinensis seed oil and ample type liquid cosmetics using the same
CN108635308A (en) A kind of moisturizing radiation-resisting whitening skin care item and preparation method thereof
KR102226774B1 (en) Detergent comprising the extract of astragalus membranaceus, polydonati rhizoma and pine leaf, and the method of manufacturing thereof
KR101585922B1 (en) Preparation method for natural shampoo composition comprising plant extracts and natural surfactant
CN109010178B (en) Shower gel and production process thereof
CN109939193A (en) A kind of composition for treating skin eczema, preparation and preparation method and application
KR101274811B1 (en) Potent anti-acne composition containing perilla frutescens and/or lygodium japonicum extract
KR102165525B1 (en) Composition for improving acne skin
CN106726993B (en) Chinese medicine hair cream and preparation method
CN104367499A (en) Water hyacinth refreshing bath lotion
CN106974858A (en) A kind of acne-removing composition of Sage Extract and its application
CN115414308B (en) Acne-removing composition, preparation method and application
KR101681258B1 (en) Natural shampoo composition comprising plant extracts and natural surfactant
KR20210040522A (en) Cosmetic composition, cosmetic mask pack comprisint the same and preperation method of the cosmetic composition
CN113057931B (en) Plant composition for preparing acne-removing preparation, acne-removing preparation and preparation method of acne-removing preparation
CN101869543A (en) Biological healthy lotion comprising pineapple, papain, shaddock, mugwort leaf extract and pearl
CN111040896A (en) Antibacterial, anti-inflammatory and skin-beautifying handmade soap

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20150325

RJ01 Rejection of invention patent application after publication