CN108524720A - A kind of Chinese medicine composition and preparation method thereof for treating diabetes - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating diabetes Download PDFInfo
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Abstract
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for treating diabetes is mainly prepared from the following raw materials in parts by weight：5~36 parts of Talinum crassifolium, 5~36 parts of Chinese yam, 23~72 parts of waxgourd peel, 5~36 parts of root of Chinese trichosanthes, 6~42 parts of the coptis, 12~50 parts of balsampear root, 11~56 parts of potentilla discolor, it is raw pull 9~49 parts, 10~35 parts of cowpea, 13~55 parts of peach gum, 21~76 parts of 9~31 parts of pueraria lobata and Chinese yew.Preparation method is：It after each raw material is crushed, is put into extraction tank, water is added, boils and carries, obtain the dregs of a decoction and extracting solution, by the dregs of a decoction and peach gum input refluxing extraction tank, ethyl alcohol is added, extracts, concentration obtains concentrate；Will concentrate be added extracting solution in, be concentrated into relative density be 1.1~1.2 clear creams to get.The present invention improves the therapeutic effect of diabetes.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition that treating diabetes and its preparation side
Method.
Background technology
Diabetes are a kind of metabolic diseases characterized by hyperglycemia.Hyperglycemia be then due to defect of insulin secretion or
Its biological effect is impaired, or both have concurrently and cause.Long-standing hyperglycemia when diabetes, cause various tissues, especially eye,
Kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.
The Chinese invention patent that authorized announcement date is CN104606474B, authorized announcement date is on 2 6th, 2018, it is public
Open a kind of with 4-8 parts of ginseng, 2-7 parts of Herba Ephedrae alkaloid, 2-5 parts of cattail pollen ketone, 2-5 parts of Radix Angelicae Pubescentis, β -4-8 parts of eucalyptus leaves oleyl alcohol,
3-9 parts of common pternopetalum root, 3-9 parts of pueraria lobata, 4-8 parts of rhizoma anemarrhenae, 4-8 parts of the fruit of glossy privet, 5-10 parts of eclipta, 5-9 parts of rhizoma atractylodis macrocephalae, peach kernel 2-5
Part, 5-9 parts of moutan bark, 3-6 parts of radix cyathulae, 3-6 parts of great burdock achene, 4-8 parts of radix scrophulariae, 3-6 parts of the root bark of Chinese wolf-berry, 2-7 parts of motherwort is original
The drug for the treatment of diabetes is made in material.The invention formula and production method are simple, unique.
The Chinese invention patent application that application publication number is CN107789479A, data of publication of application is on March 13rd, 2018,
It discloses a kind of Chinese medicines for treating diabetes, it is made of the raw material of following weight：5~7 parts of American Ginseng,
25~30 parts of Radix Astragali, 10~15 parts of Chinese yam rhizome, 10~15 parts of radix scutellariae, 15~20 parts of gypsum, 10~15 parts of the root of straight ladybell, rhizoma anemarrhenae 10~
15 parts, 10~15 parts of Radix Ophiopogonis, 20~25 parts of sealwort, 10~15 parts of mantis egg-case, 10~15 parts of root of Chinese trichosanthes, 5~7 parts of the coptis, in chicken
5~7 parts of gold, 2~5 parts of Radix Notoginseng, 5~10 parts of pueraria lobata, 5~10 parts of Schisandra chinensis.The Chinese medicine of invention treatment diabetes is just played altogether entirely
Heat-clearing Bao Jin, supplementing qi and nourishing yin, it is puckery refine the stasis of blood the benefits of.
The Chinese medicine of above-mentioned two patent disclosures has certain curative effect to treatment diabetes, but the effect is unsatisfactory.
Invention content
One aspect of the present invention technical problems to be solved are to provide a kind of Chinese medicine composition for treating diabetes, to improve
The effective percentage of traditional Chinese medicine composition for treating diabetes.
In order to solve the above-mentioned technical problem, the technical scheme is that：
A kind of Chinese medicine composition for treating diabetes, is mainly prepared from the following raw materials in parts by weight：Talinum crassifolium 5~36
Part, 5~36 parts of Chinese yam, 23~72 parts of waxgourd peel, 5~36 parts of root of Chinese trichosanthes, 6~42 parts of the coptis, 12~50 parts of balsampear root, potentilla discolor
11~56 parts, it is raw pull 9~49 parts, 10~35 parts of cowpea, 13~55 parts of peach gum, 21~76 parts of 9~31 parts of pueraria lobata and Chinese yew.
In the Chinese medicine composition for the treatment diabetes that invention provides, it is preferable that mainly by the raw material of following parts by weight
It is made：5~25 parts of Talinum crassifolium, 10~30 parts of Chinese yam, 36~63 parts of waxgourd peel, 12~31 parts of root of Chinese trichosanthes, 6~29 parts of the coptis, hardship
13~34 parts of melon root, 14~44 parts of potentilla discolor, it is raw pull 15~39 parts, 10~25 parts of cowpea, 23~35 parts of peach gum, pueraria lobata 11~
31 parts and 33~60 parts of Chinese yew.
In the Chinese medicine composition for the treatment diabetes that invention provides, it is preferable that mainly by the raw material of following parts by weight
It is made：15 parts of Talinum crassifolium, 15 parts of Chinese yam, 50 parts of waxgourd peel, 15 parts of root of Chinese trichosanthes, 15 parts of the coptis, 20 parts of balsampear root, potentilla discolor 25
Part, it is raw pull 30 parts, 20 parts of cowpea, 25 parts of peach gum, 43 parts of 20 parts of pueraria lobata and Chinese yew.
The technical problem to be solved is that provide a kind of system of Chinese medicine composition that treating diabetes for another aspect of the present invention
Preparation Method includes the following steps：
S1, weigh each raw material by weight ratio, by Talinum crassifolium, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, turn over it is white
Grass, life pulls, cowpea, pueraria lobata and taxus chinensis powder are broken to 40~80 mesh；
S2, the Talinum crassifolium by after crushing, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, potentilla discolor, it is raw pull, cowpea
Beans, pueraria lobata and Chinese yew are put into extraction tank, then water is added into extractor, and the weight ratio of the raw material and water is 1:5~8,
It boils and carries 3~8 hours, obtain the dregs of a decoction and extracting solution；
S3, the dregs of a decoction and peach gum are put into refluxing extraction tank, ethyl alcohol, the dregs of a decoction and ethyl alcohol is added into refluxing extraction tank
Weight ratio be 1:4~8,60~80 DEG C of heating and refluxing extractions 3~7 hours, obtain the dregs of a decoction and alcohol extract, by alcohol extract concentration and recovery
To without pure taste, concentrate is obtained；
S4, concentrate obtained by step S3 is added in the extracting solution obtained by step S2, be concentrated into relative density be 1.1~
1.2 clear creams to get.
In the preparation method of the Chinese medicine composition for the treatment of diabetes provided by the invention, it is preferable that described in step S3
The weight ratio of the dregs of a decoction and the ethyl alcohol is 1:5.
In the preparation method of the Chinese medicine composition for the treatment of diabetes provided by the invention, it is preferable that described in step S3
Ethyl alcohol volume fraction be 60~95%.
In the preparation method of the Chinese medicine composition for the treatment of diabetes provided by the invention, it is preferable that described in step S3
Ethyl alcohol volume fraction be 80%.
In the preparation method of the Chinese medicine composition for the treatment of diabetes provided by the invention, it is preferable that described in step S3
Heating temperature be 75 DEG C.
Talinum crassifolium, is Centrospermae, Portulacaceae, and Fameflower is annual or perennial herb Talinum crassifolium Talinum
Paniculatum (Jacq.) Gaertn. is filled blood, is aid digestion, promoting the production of body fluid to quench thirst, controlling cough sputum streaked with blood.
Chinese yam, this product are the dry rhizome of Dioscoreaceae plant Chinese yam Dioscorea oppisita Thunb..Winter cauline leaf
It is excavated after withered, cuts root head, cleaned, remove crust and fibrous root, it is dry, it practises and claims " hair yam slice "；Or crust is removed, take advantage of fresh-cut
Sheet, it is dry, referred to as " yam slice "；Also have in the loose straight drying Chinese yam , Zhi Cheongju water of selection, be dipped into without the dry heart, it is bored, it cuts
Neat both ends, are twisted into cylindric with plank, are dried, polishing, are practised and are claimed " light yam ".Sweet and neutral.Returns spleen, lung, kidney channel.Tonifying spleen nourishing the stomach, it is raw
Tianjin benefit lung, the puckery essence of kidney tonifying.For spleen eating less, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, and under band, frequent micturition, abnormal heat is quenched one's thirst.Bran
Stir-baked RHIZOMA DIOSCOREAE good efficacy to suffering from a deficiency of the kidney.For spleen eating less, diarrhea loose stool, leukorrhea.
Waxgourd peel, this product are the drying outer layer fruit of cucurbitaceous plant wax gourd Benincasa hispida (Thunb.) Cogn.
Skin.When edible wax gourd, cleans, cut and take outside rind, dry.It is sweet, it is cool.Returns spleen, small intestinl channel.Inducing diuresis to remove edema.For oedema turgor,
Difficult urination, hot summer weather is thirsty, scanty drak urine.
Root of Chinese trichosanthes, this product are cucurbitaceous plant snakegourd Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms
The dry root of Trichosanthes rosthornii Harms.Autumn, the excavation of two season of winter, clean, remove crust, segment or vertical profile
It is dry at valve.Sweet, slight bitter, is slightly cold.It attaches to the lung and stomach meridians.Clearing heat-fire promotes the production of body fluid to quench thirst, detumescence and apocenosis.For pyreticosis polydipsia, lung heat
Cough caused by dryness, Heat Diabetes, sore swollen toxin.
The coptis, this product are ranunculaceae plant coptis Coptis chinensis Franch., triangle leaf coptis Coptis
Deltoidea C.Y.Cheng et Hsiao or cloud connect the dry rhizome of Coptisteeta Wall..Three of the above is practised respectively
Claim " taste company ", " refined company ", " cloud company ".Autumn excavates, and removes fibrous root and silt, dry, hits residual fibrous root.Hardship is trembled with fear.The thoughts of returning home,
Spleen, stomach, liver, courage, large intestine channel.Heat-clearing and damp-drying drug, purging intense heat and detonicating.For damp and hot feeling of fullness, acid regurgitation, rush down dysentery, jaundice, high fever god are vomitted
Dusk, heart-fire hyperactivity, dysphoria and insomnia, palpitation and uneasiness, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells furunculosis；It is outer to control eczema, wet sore,
Duct is suppurated.It is burning hot that prepared RHIZOMA COPTIDIS with vino is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For hot eyes, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach anti-vomiting.It is mutually tied for fever and chills, it is wet
Hanker hindering, feeling of fullness vomiting.The easypro liver anti-vomiting of cornel coptis.For liver-stomach disharmony, acid regurgitation is vomitted.
Balsampear root is the root of cucurbitaceous plant balsam pear Momordica charantia L..With clearing away damp-heat, the work(of removing toxic substances
Effect.It is usually used in damp-heat dysentery, has blood in stool, furuncle swelling toxin, acute toothache.
Potentilla discolor, this product are the drying herb of rosaceous plant potentilla discolor Potentilla discolor Bge..Summer, autumn
Two seasons excavated before blooming, and removed silt and impurity, dry.Sweet, slight bitter is put down.Return liver, stomach, large intestine channel.It is clearing heat and detoxicating, stop dysentery, only
Blood.For damp-heat dysentery, carbuncle sore tumefacting virus, blood-head tells nosebleed is had blood in stool, uterine bleeding.
Life pulls, and is perennial herb, 13~30 centimetres high.Rhizome is elongated, it is horizontal walk, the close squama by dark brown lanceolar
Piece；Root shape, dark brown, dense palea.Spring, summer, autumn can harvest, and remove rhizome and fibrous root, dry.It is sweet, bitter, it is slightly cold.Return
Lung, bladder warp.Promoting diuresis for stranguria, clearing lung-heat expel the heat-evil.Leaching pain is controlled, hematuria, lithangiuria, ephritis, uterine bleeding, dysentery, cough with lung heat is chronic
Tracheitis, metal-inflicted wound, ulcer.
Cowpea, the seed or pod of leguminous herbaceous plant cowpea Vigna unguiculata.It is sweet in flavor, mild-natured.For taste
Weak, anorexia and loose stool；Women's lukorrhagia due to hypofunction of the spleen or damp and hot turbid urine, difficult urination.
Peach gum is rosaceous plant peach Amygdalus persica L. or mountain peach Amygdalus davidiana
(Carriere) resin being secreted in de Vos ex Henry barks.Peach originates in China, and various regions are generally cultivated.Mountain peach point
It is distributed in the ground such as Hebei, Shanxi, Shaanxi, Gansu, Shandong, Henan, Sichuan, Yunnan.The effect of with blood, treating stranguria, stop dysentery.For
Blood lump in the abdomen, urolithiasis, dysentery, abdominal pain, diabetes, chyluria.
Pueraria lobata, this product are the dry root of legume pueraria lobata Pueraria lobata (Willd.) Ohwi.It practises and claims elegant jessamine.
Autumn, the excavation of two season of winter, take advantage of fresh-cut into sheet or fritter；It is dry.It is sweet, pungent, it is cool.Returns spleen, stomach, lung channel.Expelling pathogenic factors from muscles and skin is brought down a fever, and is promoted the production of body fluid only
Yearningly, promoting eruption, Shengyang Zhixie, clearing and activating the channels and collaterals, relieving alcoholism.It has a headache for fever caused by exogenous pathogens, stiff nape and back is thirsty, quenches one's thirst, and measles is not
Thoroughly, hot dysentery, diarrhea, dizziness and headache, hemiplegia, chest impediment and cardialgia, during wine poison is hindered.
Chinese yew, this product are the drying branch of taxaceae plant yew Taxus chinensis (Pilger) Rehd.
Leaf.
The therapeutic effect of diabetes is improved due to the use of rational raw material and proportioning using above-mentioned technical proposal.
It is raw in the present invention to pull with potentilla discolor to improving treating diabetes total effective rate with synergistic function.It improves in the present invention
Treated effect of the drug composition to diabetes.
Specific implementation mode
The specific implementation mode of the present invention is described further below.It should be noted that for these implementations
The explanation of mode is used to help understand the present invention, but does not constitute limitation of the invention.In addition, invention described below
Involved technical characteristic can be combined with each other as long as they do not conflict with each other in each embodiment.
Embodiment 1
A kind of Chinese medicine composition for treating diabetes is present embodiments provided, mainly by the raw material system of following parts by weight
At：36 parts of Talinum crassifolium, 5 parts of Chinese yam, 72 parts of waxgourd peel, 5 parts of root of Chinese trichosanthes, 6 parts of the coptis, 50 parts of balsampear root, 11 parts of potentilla discolor, life are pulled
Hold together 49 parts, 35 parts of cowpea, 13 parts of peach gum, 76 parts of 31 parts of pueraria lobata and Chinese yew.
The preparation method of the Chinese medicine composition of the treatment diabetes, includes the following steps：
S1, weigh each raw material by weight ratio, by Talinum crassifolium, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, turn over it is white
Grass, life pulls, cowpea, pueraria lobata and taxus chinensis powder are broken to 40 mesh；
S2, the Talinum crassifolium by after crushing, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, potentilla discolor, it is raw pull, cowpea
Beans, pueraria lobata and Chinese yew are put into extraction tank, then water is added into extractor, and the weight ratio of raw material and water is 1:5, boil that carry 8 small
When, obtain the dregs of a decoction and extracting solution；
S3, the dregs of a decoction and peach gum are put into refluxing extraction tank, ethyl alcohol, the weight of the dregs of a decoction and ethyl alcohol is added into refluxing extraction tank
Amount is than being 1:8,60 DEG C of heating and refluxing extractions 7 hours, obtain the dregs of a decoction and alcohol extract, by alcohol extract concentration and recovery to without pure taste, obtain dense
Contracting object；
S4, the concentrate obtained by step S3 is added in the extracting solution obtained by step S2, it is 1.1 clear to be concentrated into relative density
Cream to get.
Embodiment 2
A kind of Chinese medicine composition for treating diabetes is present embodiments provided, mainly by the raw material system of following parts by weight
At：5 parts of Talinum crassifolium, 36 parts of Chinese yam, 23 parts of waxgourd peel, 36 parts of root of Chinese trichosanthes, 42 parts of the coptis, 12 parts of balsampear root, 56 parts of potentilla discolor, life
Pull 9 parts, 10 parts of cowpea, 55 parts of peach gum, 21 parts of 9 parts of pueraria lobata and Chinese yew.
The preparation method of the Chinese medicine composition of the treatment diabetes, includes the following steps：
S1, weigh each raw material by weight ratio, by Talinum crassifolium, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, turn over it is white
Grass, life pulls, cowpea, pueraria lobata and taxus chinensis powder are broken to 80 mesh；
S2, the Talinum crassifolium by after crushing, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, potentilla discolor, it is raw pull, cowpea
Beans, pueraria lobata and Chinese yew are put into extraction tank, then water is added into extractor, and the weight ratio of raw material and water is 1:8, boil that carry 3 small
When, obtain the dregs of a decoction and extracting solution；
S3, the dregs of a decoction and peach gum are put into refluxing extraction tank, ethyl alcohol, the weight of the dregs of a decoction and ethyl alcohol is added into refluxing extraction tank
Amount is than being 1:4,80 DEG C of heating and refluxing extractions 3 hours, obtain the dregs of a decoction and alcohol extract, by alcohol extract concentration and recovery to without pure taste, obtain dense
Contracting object；
S4, the concentrate obtained by step S3 is added in the extracting solution obtained by step S2, it is 1.2 clear to be concentrated into relative density
Cream to get.
Embodiment 3
A kind of Chinese medicine composition for treating diabetes is present embodiments provided, mainly by the raw material system of following parts by weight
At：15 parts of Talinum crassifolium, 15 parts of Chinese yam, 50 parts of waxgourd peel, 15 parts of root of Chinese trichosanthes, 15 parts of the coptis, 20 parts of balsampear root, 25 parts of potentilla discolor,
It is raw pull 30 parts, 20 parts of cowpea, 25 parts of peach gum, 43 parts of 20 parts of pueraria lobata and Chinese yew.
The preparation method of the Chinese medicine composition of the treatment diabetes, includes the following steps：
S1, weigh each raw material by weight ratio, by Talinum crassifolium, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, turn over it is white
Grass, life pulls, cowpea, pueraria lobata and taxus chinensis powder are broken to 60 mesh；
S2, the Talinum crassifolium by after crushing, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, potentilla discolor, it is raw pull, cowpea
Beans, pueraria lobata and Chinese yew are put into extraction tank, then water is added into extractor, and the weight ratio of raw material and water is 1:7, boil that carry 5 small
When, obtain the dregs of a decoction and extracting solution；
S3, the dregs of a decoction and peach gum are put into refluxing extraction tank, ethyl alcohol, the weight of the dregs of a decoction and ethyl alcohol is added into refluxing extraction tank
Amount is than being 1:6,70 DEG C of heating and refluxing extractions 6 hours, obtain the dregs of a decoction and alcohol extract, by alcohol extract concentration and recovery to without pure taste, obtain dense
Contracting object；
S4, the concentrate obtained by step S3 is added in the extracting solution obtained by step S2, it is 1.2 clear to be concentrated into relative density
Cream to get.
Embodiment 4
A kind of Chinese medicine composition for treating diabetes is present embodiments provided, mainly by the raw material system of following parts by weight
At：30 parts of Talinum crassifolium, 20 parts of Chinese yam, 45 parts of waxgourd peel, 21 parts of root of Chinese trichosanthes, 16 parts of the coptis, 38 parts of balsampear root, 33 parts of potentilla discolor,
54 parts of 15 parts of cowpea, 34 parts of peach gum, 17 parts of pueraria lobata and Chinese yew.
The preparation method of the Chinese medicine composition of the treatment diabetes, includes the following steps：
S1, weigh each raw material by weight ratio, by Talinum crassifolium, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, turn over it is white
Grass, cowpea, pueraria lobata and taxus chinensis powder are broken to 70 mesh；
S2, the Talinum crassifolium by after crushing, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, potentilla discolor, cowpea, pueraria lobata and
Chinese yew is put into extraction tank, then water is added into extractor, and the weight ratio of raw material and water is 1:6, it boils and carries 4 hours, obtain the dregs of a decoction
And extracting solution；
S3, the dregs of a decoction and peach gum are put into refluxing extraction tank, ethyl alcohol, the weight of the dregs of a decoction and ethyl alcohol is added into refluxing extraction tank
Amount is than being 1:6,65 DEG C of heating and refluxing extractions 4 hours, obtain the dregs of a decoction and alcohol extract, by alcohol extract concentration and recovery to without pure taste, obtain dense
Contracting object；
S4, the concentrate obtained by step S3 is added in the extracting solution obtained by step S2, it is 1.2 clear to be concentrated into relative density
Cream to get.
Embodiment 5
A kind of Chinese medicine composition for treating diabetes is present embodiments provided, mainly by the raw material system of following parts by weight
At：16 parts of Talinum crassifolium, 22 parts of Chinese yam, 63 parts of waxgourd peel, 14 parts of root of Chinese trichosanthes, 37 parts of the coptis, 19 parts of balsampear root, it is raw pull 36 parts,
47 parts of 21 parts of cowpea, 41 parts of peach gum, 21 parts of pueraria lobata and Chinese yew.
The preparation method of the Chinese medicine composition of the treatment diabetes, includes the following steps：
S1, each raw material is weighed by weight ratio, Talinum crassifolium, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, life are pulled
Hold together, cowpea, pueraria lobata and taxus chinensis powder are broken to 60 mesh；
S2, the Talinum crassifolium by after crushing, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, it is raw pull, cowpea, pueraria lobata and
Chinese yew is put into extraction tank, then water is added into extractor, and the weight ratio of raw material and water is 1:7, it boils and carries 7 hours, obtain the dregs of a decoction
And extracting solution；
S3, the dregs of a decoction and peach gum are put into refluxing extraction tank, ethyl alcohol, the weight of the dregs of a decoction and ethyl alcohol is added into refluxing extraction tank
Amount is than being 1:5,75 DEG C of heating and refluxing extractions 6 hours, obtain the dregs of a decoction and alcohol extract, by alcohol extract concentration and recovery to without pure taste, obtain dense
Contracting object；
S4, the concentrate obtained by step S3 is added in the extracting solution obtained by step S2, it is 1.2 clear to be concentrated into relative density
Cream to get.
Test example
Clinical data：Selection meets diabetes diagnostic criterion Patients with 300 Cases as subjects, be randomly divided into control group,
5 groups of 1 group of embodiment, 2 groups of embodiment, 3 groups of embodiment, 4 groups of embodiment and embodiment, every group 50.Through comparing, each group patient's
The general information such as gender, age, drug resistance situation compare no significant difference (P>0.05) it, is comparable.Control group is administered
Oral melbine hydrocloride piece, three times a day, each 0.25g.1 group of embodiment, 2 groups of embodiment, 3 groups of embodiment, 4 groups of embodiment
With 5 groups of clear creams for taking orally 1 to 5 gained of embodiment respectively of embodiment, three times a day, each 10g.
Inclusion criteria:All have that polydipsia, the paddy that disappears are easily hungry, urine is more and sweet tea, body are gradually shown in that patient of becoming thin can be made a definite diagnosis
For diabete (diabetes)；All lassitude hypodynamias, spontaneous sweating, shortness of breath lazyness speech, thirst and liking drink, dysphoria in chestpalms-soles, palpitation and insomnia, urinate it is red
Constipation, red tongue with a little fluid, tongue body fat big, tongue is thin or flower is shelled, small and wiry pulse or number person, as Qi and Yin deficiency diabetes mellitus；There are diabetes
Symptom, any time blood glucose ＞ 11.1mmol/L or fasting blood-glucose ＞ 7.0mmol/L；All patients meet 1 in above-mentioned 3
Item or 1 or more.
Observation of curative effect：1, fasting blood-glucose, 2, glycosylated hemoglobin, 3, total cholesterol, triglycerides, 4, blood, urine, stool it is normal
Rule and electrocardiogram, hepatic and renal function.
Criterion of therapeutical effect：With reference to the Ministry of Public Health《New Chinese medicine treats the guideline of clinical investigations of diabete》It drafts.
Treatment results see the table below：
As seen from the above table, the total effective rate of 1 to 3 group of embodiment is suitable with the total effective rate of control group, no significant difference.
Embodiment 4 and 5 groups of total effective rate and the total effective rate of 1 to 3 group of control group and embodiment have significant difference.In embodiment
Reduce life in 4 in constitutive material to pull, reduces potentilla discolor in constitutive material in embodiment 5.As it can be seen that life is pulled and be turned over white
Grass has synergistic function to improving treating diabetes total effective rate.
Embodiments of the present invention are explained in detail above, but the present invention is not limited to described embodiments.It is right
For those skilled in the art, in the case where not departing from the principle of the invention and spirit, these embodiments are carried out more
Kind change, modification, replacement and modification, still fall in protection scope of the present invention.
Claims (8)
1. a kind of Chinese medicine composition for treating diabetes, which is characterized in that be mainly prepared from the following raw materials in parts by weight：Natives
5~36 parts of ginseng, 5~36 parts of Chinese yam, 23~72 parts of waxgourd peel, 5~36 parts of root of Chinese trichosanthes, 6~42 parts of the coptis, balsampear root 12~50
Part, 11~56 parts of potentilla discolor, it is raw pull 9~49 parts, 10~35 parts of cowpea, 13~55 parts of peach gum, 9~31 parts of pueraria lobata and Chinese yew
21~76 parts.
2. the Chinese medicine composition for the treatment of diabetes according to claim 1, which is characterized in that mainly by following parts by weight
Raw material be made：5~25 parts of Talinum crassifolium, 10~30 parts of Chinese yam, 36~63 parts of waxgourd peel, 12~31 parts of root of Chinese trichosanthes, the coptis 6~29
Part, 13~34 parts of balsampear root, 14~44 parts of potentilla discolor, it is raw pull 15~39 parts, 10~25 parts of cowpea, 23~35 parts of peach gum, Pueraria lobota
33~60 parts of 11~31 parts of root and Chinese yew.
3. the Chinese medicine composition for the treatment of diabetes according to claim 2, which is characterized in that mainly by following parts by weight
Raw material be made：15 parts of Talinum crassifolium, 15 parts of Chinese yam, 50 parts of waxgourd peel, 15 parts of root of Chinese trichosanthes, 15 parts of the coptis, 20 parts of balsampear root, turn over it is white
25 parts of grass, it is raw pull 30 parts, 20 parts of cowpea, 25 parts of peach gum, 43 parts of 20 parts of pueraria lobata and Chinese yew.
4. treating the preparation method of the Chinese medicine composition of diabetes according to claims 1 to 3 any one of them, feature exists
In including the following steps：
S1, each raw material is weighed by weight ratio, by Talinum crassifolium, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, potentilla discolor, life
It pulls, cowpea, pueraria lobata and taxus chinensis powder are broken to 40~80 mesh；
S2, the Talinum crassifolium by after crushing, Chinese yam, waxgourd peel, root of Chinese trichosanthes, the coptis, balsampear root, potentilla discolor, it is raw pull, cowpea, Pueraria lobota
Root and Chinese yew are put into extraction tank, then water is added into extractor, and the weight ratio of the raw material and water is 1:5~8, it boils and carries 3
~8 hours, obtain the dregs of a decoction and extracting solution；
S3, the dregs of a decoction and peach gum are put into refluxing extraction tank, ethyl alcohol, the weight of the dregs of a decoction and ethyl alcohol is added into refluxing extraction tank
Amount is than being 1:4~8,60~80 DEG C of heating and refluxing extractions 3~7 hours, obtain the dregs of a decoction and alcohol extract, by alcohol extract concentration and recovery to nothing
Pure taste, obtains concentrate；
S4, the concentrate obtained by step S3 is added in the extracting solution obtained by step S2, it is 1.1~1.2 to be concentrated into relative density
Clear cream to get.
5. the preparation method of the Chinese medicine composition for the treatment of diabetes according to claim 4, which is characterized in that in step S3
The weight ratio of the dregs of a decoction and the ethyl alcohol is 1:5.
6. the preparation method of the Chinese medicine composition for the treatment of diabetes according to claim 4, which is characterized in that in step S3
The volume fraction of the ethyl alcohol is 60~95%.
7. the preparation method of the Chinese medicine composition for the treatment of diabetes according to claim 6, which is characterized in that in step S3
The volume fraction of the ethyl alcohol is 80%.
8. the preparation method of the Chinese medicine composition for the treatment of diabetes according to claim 4, which is characterized in that in step S3
The heating temperature is 75 DEG C.
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| CN108743753A (en) * | 2018-08-13 | 2018-11-06 | 红河鑫润生物技术开发有限公司 | A kind of Chinese medicine composition, preparation method and the usage |
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Application publication date: 20180914 |