CN105950407A - Alopecia-prevention health care wine and production method thereof - Google Patents

Alopecia-prevention health care wine and production method thereof Download PDF

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CN105950407A
CN105950407A CN201610585677.5A CN201610585677A CN105950407A CN 105950407 A CN105950407 A CN 105950407A CN 201610585677 A CN201610585677 A CN 201610585677A CN 105950407 A CN105950407 A CN 105950407A
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alopecia
fructus
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wine
agkistrodon
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秦文雄
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Abstract

The invention discloses alopecia-prevention health care wine. The health care wine is made from, by weight, 60-100 parts of plastrum testudinis, 200-240 parts of bungarus multicinctus bodies, 30-50 parts of bungarus multicinctus gallbladder, 30-50 parts of cock testis, 20-30 parts of fructus arctii, 20-30 parts of ardisia maculosa mez, 20-30 parts of omei linden root-bark, 20-30 parts of caudate tickclover herb root, 18-20 parts of fennel, 18-20 parts of obscured homalomena rhizome, 18-20 parts of cacumen biotae, 18-20 parts of wolfberry fruit, 12-14 parts of hawthorn, 12-14 parts of Potentilla discolor Bge., 10-12 parts of fructus anisi stellati, 10-12 parts of longan pulp, 10-12 parts of almond, 100-200 parts of sugar liquid and 8000-10000 parts of rice wine. The alopecia-prevention health care wine is formed by matching Chinese herbal medicine with the effects of invigorating spleen and supplementing qi and nourishing yin and tonifying blood, and has remarkable treatment effects on blood wind alopecia, alopecia caused by side effects of medicine, postpartum alopecia, alopecia caused by anemia, alopecia caused by malnutrition and the like.

Description

The health promoting wine of preventing and treating alopecia and production method thereof
Technical field
The invention belongs to field of health care wine, be specifically related to a kind of health promoting wine preventing and treating alopecia and production method thereof.
Background technology
China has long health promoting wine and brewages and drink history, and health promoting wine culture is of long standing and well established.Health promoting wine industry development all has a very large change to today, industry, market, management etc..The raising of income level of resident, the improvement of quality of life, reinforcement and China's white collar backbone elite " subhealth state " trend of country's domestic demand policy are increasingly severe, are all greatly promoted the development of health promoting wine industry.
Chinese medicament healthcare wine, refer to rice wine or jowar wine make immersed with the Chinese medicine of QI and blood regulating Yu liver and kidney tonifying effect, nutritious to human body, the wine of the health care effect of getting rid of illness can be played.The existing thousands of years history of Chinese medicament healthcare wine, is the important component part of Chinese Medicine science.Chinese medicament healthcare wine has early occurred, has medicated wine to control the record of disease body-building the most bar none in the successive dynasties medicine works of China.Along with the progress of science and technology, Chinese medicament healthcare wine, on the basis of the traditional handicraft of Traditional Chinese medicinal wine, has evolved to utilize the modernization meanses such as extraction, extraction and biological engineering, extracts Effective Component of Chinese Medicine and make the Chinese medicament healthcare wine of high-load.
Alcoholic strength temperature and acrid in the mouth, Wen Zheneng cold relieving, pungent person can dissipate.The pure grain wine of height has promotion human intestines and stomach's secretion, helps digest absorption, strengthens blood circulation, promote tissue metabolism, strengthens the effect of cell viability, so responsible drinking energy dredging the meridian, circulation of qi promoting and blood, warming YANG to expel cold, dispersing the stagnated live-QI to relieve the stagnation of QI, a surname's feelings are freely anticipated.Wine is the elite that corn is brewageed, appropriate few drink, moreover it is possible to tonification the intestines and stomach.Compatibility is particular about in Chinese medicament healthcare wine medication, is healthy and strong based on health preserving, different according to function, can be divided into the types such as QI invigorating, blood enriching and yin nourishing, YANG invigorating and qi and blood tonifying.
Chinese medicament healthcare wine is the wine kind that infiltration and development gets up on the basis of other drinks, and Chinese medicament healthcare wine proportion in the yield of whole alcoholic drink is the least.Present circumstances is seen, Chinese medicament healthcare wine increasingly causes the concern inside and outside industry, Chinese medicament healthcare wine amplification in recent years is annual all more than 20%, its production scale is really significantly improved compared with other wine kinds, and this point is to be currently undertaken by the result that the research staff of Chinese medicament healthcare wine, management personnel and marketing personnel make great efforts.But in terms of the automatization of the equipment of production, Chinese medicament healthcare wine has the biggest gap compared with medicated beer, Grape Wine Industry, also there being the biggest gap in terms of Studies on Analysis of Flavor Constituents compared with liquor industry, these are not enough and gap should cause the great attention of industry colleagues.And the advantage of Chinese medicament healthcare wine is abundant raw material, producing equipment fairly simple, with short production cycle, the adjustable leeway of physical and chemical composition is big, and these advantages are that other wine kinds cannot be by comparison.Therefore, Chinese medicament healthcare wine has become one of focus of current developmental research.
Chinese medicament healthcare wine, was referred to as medicated wine in the past, had had differentiation in recent years, can be regarded as the branch of tradition medicated wine, also be the extension of common white spirit.Although both adding medical material in brewing process, but both having certain difference.Both are with root homology, and Chinese medicament healthcare wine comes from medicated wine, is derived from medicated wine, is different from again medicated wine.First, category belonging to both is different, and Chinese medicament healthcare wine belongs to the category of alcoholic drink, and medicated wine belongs to the category of " medicine ".Chinese medicament healthcare wine is typically produced by the food enterprises, and by food control, department supervises;Medicated wine is produced by general pharmaceutical factory, Drug Administration supervise;Secondly, function is the most different.Age and sex are not particularly restricted by Chinese medicament healthcare wine, and main use, to liking healthy or sub-health population, is used for regulating physiological function, for the purpose of health care, health preserving, being healthy and strong, meets the health care needs of consumer.Medicated wine has stronger specific aim, the suitability, uses object to be mainly Disease.Need to take under the prescription doctor or the guidance professional person, be used for treatment disease of curing the disease, have specific medical function, have indication, function to cure mainly, usage and consumption, typically can not abuse.
Along with the rhythm of life of people is gradually accelerated, operating pressure continues to increase, and the continuous deterioration of living environment, people pay close attention to the most in terms of health, but the nursing for hair is the most too much paid close attention to, and the situation increasingly rejuvenation of alopecia occur now.
Summary of the invention
It is an object of the invention to provide a kind of prevention Alopecia-treatment health-care wine, not only can realize building body, and can the efficiency health-care wine of anti-alopecia-stopping, ratio Chinese medicine taking convenience, therapeutic effect is notable and less than general Western medicine toxic and side effects.
The present invention realizes by the following technical solutions:
A kind of health promoting wine preventing and treating alopecia, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 60-100, Agkistrodon ichthyosis 200-240, Agkistrodon Fel Serpentis 30-50, cock testis 30-50, Fructus Arctii 20-30, ardisia maculosa Mez 20-30, Cortex Tiliae omeiensis Radicis 20-30, Radix Desmodii Caudati 20-30, Fructus Foeniculi 18-20, Rhizoma Homalomenae 18-20, Cacumen Platycladi 18-20, Fructus Lycii 18-20, Fructus Crataegi 12-14, Herba Potentillae Discoloris 12-14, Fructus Anisi Stellati 10-12, Arillus Longan 10-12, Semen Armeniacae Amarum 10-12, sugar liquid 100-200, rice wine 8000-10000.
The health promoting wine of described preventing and treating alopecia, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 60, Agkistrodon ichthyosis 200, Agkistrodon Fel Serpentis 30, cock testis 30, Fructus Arctii 20, ardisia maculosa Mez 20, Cortex Tiliae omeiensis Radicis 20, Radix Desmodii Caudati 20, Fructus Foeniculi 18, Rhizoma Homalomenae 18, Cacumen Platycladi 18, Fructus Lycii 18, Fructus Crataegi 12, Herba Potentillae Discoloris 12, Fructus Anisi Stellati 10, Arillus Longan 10, Semen Armeniacae Amarum 10, sugar liquid 100, rice wine 8000.
The health promoting wine of described preventing and treating alopecia, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 80, Agkistrodon ichthyosis 220, Agkistrodon Fel Serpentis 40, cock testis 40, Fructus Arctii 25, ardisia maculosa Mez 25, Cortex Tiliae omeiensis Radicis 25, Radix Desmodii Caudati 25, Fructus Foeniculi 19, Rhizoma Homalomenae 19, Cacumen Platycladi 19, Fructus Lycii 19, Fructus Crataegi 13, Herba Potentillae Discoloris 13, Fructus Anisi Stellati 11, Arillus Longan 11, Semen Armeniacae Amarum 11, sugar liquid 150, rice wine 9000.
The health promoting wine of described preventing and treating alopecia, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 100, Agkistrodon ichthyosis 240, Agkistrodon Fel Serpentis 50, cock testis 50, Fructus Arctii 30, ardisia maculosa Mez 30, Cortex Tiliae omeiensis Radicis 30, Radix Desmodii Caudati 30, Fructus Foeniculi 20, Rhizoma Homalomenae 20, Cacumen Platycladi 20, Fructus Lycii 20, Fructus Crataegi 14, Herba Potentillae Discoloris 14, Fructus Anisi Stellati 12, Arillus Longan 12, Semen Armeniacae Amarum 12, sugar liquid 200, rice wine 10000.
The acquisition methods of described Agkistrodon ichthyosis and Agkistrodon Fel Serpentis is: take some Agkistrodon, and gill after slaughtering reservation Fel Serpentis, is cleaned by Naja ichthyosis and dries moisture, obtains Agkistrodon ichthyosis and Agkistrodon Fel Serpentis.
Described cock testis is to select the testis that takes off with just opening the cock crowed, cut open after cooking, dry after obtain.
Described sugar liquid is to obtain after the Chinese liquor adding with crystal sugar and accounting for gross weight 2-3 times amount warms dissolving, filtration.
Described rice wine is with brown rice as raw material, and with saccharifying enzyme, yeast for ferment agent, through adding slurry form without adjuvant steaming and decocting cultivation fermentation, distillation, alcohol content is 50 60%.
The health promoting wine of described preventing and treating alopecia, its production method comprises the following steps:
(1) by Fructus Arctii 20-30, ardisia maculosa Mez 20-30, Cortex Tiliae omeiensis Radicis 20-30, Radix Desmodii Caudati 20-30, Fructus Foeniculi 18-20, Rhizoma Homalomenae 18-20, Cacumen Platycladi 18-20, Fructus Lycii 18-20, Fructus Crataegi 12-14, Herba Potentillae Discoloris 12-14, Fructus Anisi Stellati 10-12, Arillus Longan 10-12 and Semen Armeniacae Amarum 10-12, clean and remove foreign body, foreign material;
(2) by the raw material co-grinding of step (1), cross 100 mesh sieves, be placed in the container of sealing, add Carapax et Plastrum Testudinis 60-100, Agkistrodon ichthyosis 200-240, Agkistrodon Fel Serpentis 30-50, cock testis 30-50 and rice wine 18000-30000, seal and soak 35-40 days;
(3) immersion seven days, stir 5-6 time with willow rod every day, within after seven days every 3-5 days, stir 1 time, after treating that effective ingredient is dissolved in wine, are filtrated to get filtrate A and filtering residue;
(4) taking step (3) gained filtering residue to carry out squeezing and obtain pressed liquor, then merged with pressed liquor by step (3) gained filtrate A, stand 24 hours, supernatant obtains liquor B by the filter of aperture < 2 μm;
(5) sugar liquid 100-200 is added liquor B mixing, tinning or bottling, instantaneous sterilizing, seal, obtain the health promoting wine of described preventing and treating alopecia.
The present invention prevents and treats the health promoting wine of alopecia and is formed by the Chinese herbal medicine compatibility of invigorating the spleen and benefiting QI, effect of nourishing YIN and supplementing blood, the alopecias such as alopecia, puerperal alopecia, anemia alopecia and the malnutrition causing blood wind alopecia, side effects of pharmaceutical drugs all have significant curative effect, with the kidney invigorating, QI invigorating, invigorate blood circulation, the effect such as YIN nourishing, strong body, its drinking method is: every day 2 times, each 15-30ML.
In the raw material of Chinese medicine that the present invention chooses, active ingredient is analyzed as follows:
Carapax et Plastrum Testudinis be Testudinidae animal Testudinis (Chinemys reevesii(Gray)) carapace.The whole year all can catch, but with autumn, winter for many.After killing, reject muscles, take its sternite, clean, dry or dry, be referred to as " blood version ".As boiled the sternite after death taken, it is referred to as " soup version ".Past commodity are sternite, the most also begin with carapace.The sternite being dried, slightly in en plaque, rectangular ellipse, rib dissepiment invests both sides, slightly in wing.Long 10~20 centimetres, wide 7~10 centimetres, thickness about 5 millimeters, outer surface yellowish-brown, to brown, has a purple brown texture sometimes.Carapax et Plastrum Testudinis: soak with clear water, scrape off residual meat, cleans, dries, knock fritter.Nature and flavor with return through: salty sweet, flat.Enter liver, kidney two warp.Function cures mainly: YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone.Control deficiency of kidney yin, hectic fever due to YIN-deficiency consumptive fever, spit blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.
Agkistrodon (Bungarus multicinctus), it was commonly called as Ji Xia, Bai Jiehei, Bungarus Parvus, silver first band, silver iron clad etc..Toxicity is extremely strong, for the fourth-largest poisonous snake in land.Chemical composition: Serpentis body is containing 21 kinds of elements such as protein, fat, aminoacid and calcium, phosphorus, magnesium, ferrum, aluminum, zinc, strontium, titanium, manganese, vanadium, copper.Serpentis body ash 19%, loss on drying 11.63%-12.45%, water-soluble extractives 1.36%-19.70%, 95% ethanol soluble extraction 0.54%-5.40%, containing cholic acid in bile.Nature and flavor: sweet in the mouth;Salty;Warm in nature;Poisonous.Gui Jing: liver;Spleen channel.Function cures mainly: dispelling wind and removing obstruction in the collateral;Arresting convulsion relieving convulsion.Main air pain of dampness syndrome;Spasm of muscles and vessels;Middle air port eye is oblique;Hemiplegia;Infantile convulsion;Tetanus;Leprosy;Scabies;Syphilis;Malignant boil.Multibanded krait gall: profile is oblong, two ends are the sharpest, and most advanced and sophisticated bile duct base portion is thick and tilts, and hooks in obvious tack.Bile is orange.Feeble QI raw meat, hides bitter first ,sweet later.There is expelling wind and removing dampness, refrigerant improving eyesight, detoxify and go effect of miliaria;The adjustable nervous system mending people, hormonal system and immune system, delay body aging.
Cock i.e. cock, cock testis nature and flavor: sweet, flat, kidney invigorating and YANG supporting, stimulating milk secretion.Cure mainly: suffer from a deficiency of the kidney, sexual neurasthenie, seminal emission, spermatorrhea, sexual impotence, the soreness of waist are weak, tinnitus, cold womb are infertile etc. unique curative effect.Having the health-care effect of high YIN nourishing and YANG strengthening, its medical, edible is worth the highest.It is used for steeping in wine, there is the effects such as warming the kidney to invigorate YANG, tranquilizing by nourishing the heart, bone strengthening be anti-ageing.
Fructus Arctii (Latin plant animal mineral name:Fructus Arctii), for the dry mature fruit of Compositae biennial herb plant Fructus Arctii.In long inverted ovoid, the most flat, microbend, long 5~7mm, wide 2~3mm.Surface taupe, band atropurpureus speckle, there are several vertical ribs, generally 1~2, centre is more apparent.The blunt circle in top, slightly wider, end face has annulus, middle tool point-like style vestiges;Base portion is the narrowest, and areloe color is thin.Peel is harder, cotyledon 2, and yellowish white is High oleic.Odorless, after bitter in the mouth micro-pungent and slightly fiber crops tongue.Gather during fruit maturation in autumn infructescence, dry, lay fruit, remove impurity, then dry.Life is used or fries use, and the used time smashs to pieces.There is dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, effect of removing toxic substances and promoting subsidence of swelling.Belong to wind-heat-dispersing medicinal in diaphoretic medicine.Modern study, Fructus Arctii can be additionally used in preventing and treating diabetic nephropathy;The arctigenin that Arctium lappa fruit generates through hydrolysis containing arctigenin has active anticancer.
Ardisia maculosa Mez (Latin plant animal mineral name:Ardisia maculosa Mez) it is a kind under Myrsinacea Ardisa.Happiness the moon, is born in the mountain valley of height above sea level 270-1150m, the dark and damp place of hillside sylvan life.Originate in SOUTHERN CHINA.Herb is used as medicine.Nature and flavor: bitter, temperature.Function cures mainly: regulating QI to relieve pain, relaxing muscles and tendons and activating QI and blood in the collateral, pharynx-clearing throat-benefiting.Control laryngopharynx swelling and pain, stomachache, acute enteritis, rheumatic arthritis.Fracture, traumatic injury are controlled in external.
Cortex Tiliae omeiensis Radicis (outer literary fame:root-bark of Omei Linden) it is the root bark of Oak Tree section plant high eyebrow Hibiscus syriacus.Original shape state: deciduous tree is high about 10 meters.Bud is avette, perula sharp shape or more blunt.Single leaf alternate;Rectangle or rectangular avette, long 9~11 centimetres, wide 4~7 centimetres, tip is tapering, and base portion is tiltedly justified, Quan Yuan, close by the starlike felt hair of Lycoperdon polymorphum Vitt during children;Petiole length 2~3 centimetres.Cyme, spends 9~12;Bract wire rectangle, long 14~16 centimetres, wide 2~2.2 centimetres, below close by starlike felt hair;Calyx 5, narrow triangle, outside is by Lycoperdon polymorphum Vitt felt hair, inner side villosity;5 pieces of petal, yellow, ovum shape lanceolar;Stamen is most, staminodium 5 pieces, petal-shaped;Ovary obovate, by dense Lycoperdon polymorphum Vitt felt hair, stigma 5 splits.Fruit obovate, by Lycoperdon polymorphum Vitt starlike felt hair.July at florescence.Fructescence October.Habitat branch: be born in the forest of Zhongshan District.The ground such as distribution Sichuan.Nature and flavor: bitter in the mouth is pungent, cool in nature, nontoxic.Function cures mainly: stimulates the menstrual flow and regulates the flow of vital energy.Control traumatic injury and infirmities and diseases.
Radix Desmodii Caudati is leguminous plant Desmodium caudatum (Thunb.) DC.Desmodium caudatum (Thunb.) DC.Root.9~take root October, clean, dry.Chemical composition: containing alkaloid 0.12%.Nature and flavor: bitter, temperature.1. " vegetation just side ": " warm in nature." 2. " Jiangxi medical herbs ": " is warm in nature, mildly bitter flavor." function cures mainly: dispel the wind, dehumidifying, invigorates blood circulation, removing toxic substances.Dispelling the wind and dampness pathogens lumbago, dysentery, icterohepatitis, carbuncle, scrofula, traumatic injury is hindered.
Fructus Foeniculi is samphire Fructus FoeniculiFoeniculum vuLgare Mill.Dry mature fruit.Autumn fruit just ripe time tap plant, dry, lay fruit, remove impurity.Fructus Foeniculi is also known as Fructus Foeniculi, fragrant silk dish.Fructus Foeniculi acrid in the mouth, sweet, warm.Regulate the flow of vital energy stomach invigorating, the effect such as dispersing cold for relieving pain.Fructus Foeniculi can be fried and eat, cold and dressed with sauce, bag steamed bun, makes dumplings, the taste of own delicate fragrant.TAO Hong-Jing is called: boil smelly meat, lower a little, without foul smell, it is the most fragrant that smelly beans enters end, therefore says Fructus Foeniculi.Li Shizhen (1518-1593 A.D.) is said, vulgar many bosoms girdle front of a garment is chewed, the probably name of bosom perfume, or with this also.The main component of Fructus Foeniculi is protein, fat, dietary fiber, anethole, fenchone, anisaldehyde etc..Its fragrance is essentially from anethole.The fragrance matters such as anisaldehyde.Fructus Foeniculi energy stimulating gastrointestinal neural blood vessel, promotes saliva and gastric secretion, plays appetite stimulator, digestive effect.Fructus Foeniculi acrid in the mouth is warm in nature, medically has the effects such as warming the liver kidney, warming the stomach, cold expelling.
Rhizoma Homalomenae, Chinese medicine name.For aroid Rhizoma HomalomenaeHomalomena occulta(Lour.)SchottDry rhizome.Spring, season in autumn two excavate, and clean, and remove crust, dry.Nature and flavor: bitter in the mouth, pungent, warm in nature.Gui Jing: liver, kidney channel.Function: have wind-damp dispelling, effect of strengthening bone and muscle.Cure mainly: for anemofrigid-damp arthralgia, chills and pain of the waist and kness, contracture is numb, and muscles and bones flaccidity is soft.
Cacumen Platycladi, Chinese medicine name.For Cupressaceae plant Cacumen PlatycladiPLatycladus orientalis ( L. ) FrancoDry branch top and leaf.How to gather in summer, season in autumn two, dry in the shade.Nature and flavor: bitter, puckery, cold.Gui Jing: return lung, liver, spleen channel.Effect: cooling blood for hemostasis, preventing phlegm from forming and stopping coughing, growing and blacking hair.Cure mainly: be used for spitting blood, epistaxis, spitting of blood, have blood in stool, metrostaxis, cough due to lung-heat, heat in blood alopecia, early whitening of beard and hair.
Fructus Lycii (outer literary fame:FRUCTUS LYCII), for the mature fruit of matrimony vine of solanaceae plant.When summer, autumn fruit maturation pluck, remove fruit stem, putting dries in the air at cool place corrugate to peel after, then be exposed to the sun to crust stiff, sarcocarp is soft and get final product.Meet the available low baking temperature of wet weather to dry.There is various health care functions, be the medicine-food two-purpose food of Ministry of Public Health approval.Effect of Fructus Lycii: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.Control hepatic and renal YIN deficiency, soreness of the waist and knees, dizzy, dizzy, the many tear of blurred vision, cough due to consumptive disease, quench one's thirst, seminal emission.
Fructus Crataegi (Latin plant animal mineral name:Crataegus pinnatifida Bunge), having another name called fruit, Fructus Pyri Pashiae in mountain, Rosaceae Crataegus, deciduous tree, height is up to 6 meters.Nature and flavor: sour, sweet, tepor.Gui Jing: return spleen, stomach, Liver Channel.Function cures mainly: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain;Hyperlipemia.Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving effect strengthens.For meat stagnation, dysentery is not well.
Herba Potentillae Discoloris (Latin plant animal mineral name:Potentilla discolor Bge.) it is a kind of perennial herb, root manure is big, coniform, odd number winglike compound leaf, and basal leaf has lobule 8~11 right, and top lobule is maximum, both sides lobule diminishes the most gradually, lobule narrow oblong, long 2~5 centimetres, wide 8~15 millis, stem leaf 1-2, there is palmate 3-5 lobule;Bennet is long 1-2.5 centimetre, outer by MIAOMAO;Flower diameter 1-2 centimetre;Achene nearly kidney shape, wide about 1 millimeter, smooth.The flowering fruit bearing stage 5-9 month.Can make medicinal, typically be grown under low mound patana or sparse woods in thick grass, main product Shandong, Liaoning, Anhui.Herb all can be used as medicine, heat-clearing and toxic substances removing, cooling blood for hemostasis, can treat dysentery, diarrhoea, leucorrhea, malaria, spit blood, have blood in stool, traumatic hemorrhage, bloody dysentery stomachache, chronic dysentery are more than, bleeding hemorrhoids, carbuncle sore tumefacting virus.
Fructus Anisi Stellati is Magnoliacea plant Fructus Anisi StellatiIllicium verum Hook. f. Dry mature fruit.Pluck when autumn, season in winter two fruit are by green flavescence, put and be dried or convection drying after boiling water slightly scalds.Nature and flavor: pungent, temperature.Gui Jing: return liver,kidney,spleen, stomach warp.Function cures mainly: warming YANG to expel cold, regulating QI to relieve pain.Suffer from abdominal pain for colic of cold type, lumbago due to renal deficiency, gastrofrigid vomiting, coldness and pain in the epigastrium.
Arillus Longan (Latin plant animal mineral name:Dried Longan Pulp), Arillus Longan is the aril of sapindaceous plant Arillus Longan.Main product in Fujian, Guangdong, Guangxi, the ground such as Sichuan, TaiWan, China, Yunnan and South of Guizhou are also produced in addition.Wherein Fujian yield accounts for the 50% of whole nation total output.Be usually and utilize the least longan cultivars of fruit, but want meat thickness, core is little, sugar content is high.Processing method, as choosing fruit arranges, cuts fruit, washes these operations of fruit as dried longan processing method.Then fresh fruit is placed under the sun and tans by the sun, or be placed on drying in roasting stove, drying room.Bake half-dried degree, peel off shell by hand, with finger, sarcocarp torn at fruit end plum blossom-shaped again, spread on bamboo plaque, continuing to dry sarcocarp under the sun, or dry sarcocarp in drying room, temperature controls at about 60 DEG C, but can not dry on roasting stove, otherwise yellowish pink is the most sallow and has the cigarette smell of burning.The meat that Arillus Longan is dried appropriateness is dense sweet, crisp tough, bright yellow color, and water content reaches 15% 19%.Arillus Longan sweet in the mouth, warm in nature;There are appetizing strengthening the spleen, nourishing blood to tranquillize the mind, effect of the long intelligence of qi-restoratives;Treatment anemia and dermatitis that for want of nicotinic acid causes, diarrhoea, dementia, even Mental Subnormality, have certain inhibitory action simultaneously to cancerous cell.
Semen Armeniacae Amarum (Latin plant animal mineral name:Amygdalus Communis Vas) it is the dry seed of the bitter in the mouth such as rosaceous plant Fructus Pruni or Prunus armeniaca L.var.ansu Maxim..Pluck during fruit maturation in summer, remove sarcocarp and nucleocapsid, take kernel, dry.Put shady and cool being dried to locate, Anti-moth-eating.Chemical composition: containing amygdalin about 3%, fatty oil (almond oil) about 50%, protein and various free amino acid.Amygdalin, by β-glycoside enzyme hydrolysiss such as the emulsin in Semen Armeniacae Amarum and prunases, sequentially generates wild cherry skin glycoside and melic acid nitrile, then decomposes generation benzaldehyde and hydrocyanic acid.Nature and flavor: bitter, temperature, poisonous.Gui Jing: enter lung, large intestine channel.Function cures mainly: expelling phlegm for arresting cough, relievings asthma, intestine moistening.Control exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.
Alopecia refers to the phenomenon of alopecia.The hair normally come off is at the hair of catagen and resting stage, is constantly in dynamic equilibrium owing to entering the hair of catagen and newly entering trophophase, therefore can maintain the hair of normal quantity.Pathologic alopecia refers to hair exception or excessive coming off, and its reason is a lot.Its cause of disease is not understood by modern medicine, it is considered that with nervous, dysbolismus is relevant.Motherland's medical science then thinks " hair is the sign of blood condition ", blood stored in the liver, kidney storing essence, deficiency of the liver and kindey, menses virtual loss, sends out to lose to moisten and supports the main cause into alopecia.Mention as in " General Treatise on the Cause and Symptoms of Diseases beard and hair come off opinion ": " foot-shaoyang gallbladder through also, its honor at palpus, kidney meridian through also, its Hua Fa, the arteries and veins that punching is appointed, be sea of the twelve channels, its other network is at upper lip;If blood is contained, flourish in beard and hair, therefore beard and hair is beautiful, if vim and vigour are weak, exhausts through deficient pulse, it is impossible to Rong Run, therefore beard and hair alopecia ".That is the growth of hair with come off, moist with withered original text, all full relevant with the vital essence prosperity and decline of kidney and blood.
Medicated wine of the present invention uses ten kinds of traditional Chinese medicines to form through Chinese liquor is brewed, use scalable human body essence, gas, god continuously, stimulate blood circulation, play blood circulation promoting and blood stasis dispelling, the effect of nutrition hair follicle, promote the metabolism of hair and grow up healthy and sound that the process that alleviating hair comes off stimulates the new growth sent out, fundamentally hair growth, curative effect is the most lasting.Carapax et Plastrum Testudinis, Agkistrodon ichthyosis, Agkistrodon Fel Serpentis, cock testis, Arillus Longan blood-supplementing blood-nourishing in side;Cortex Tiliae omeiensis Radicis, Semen Armeniacae Amarum, Fructus Foeniculi, Fructus Arctii, Rhizoma Homalomenae air making-up and spleen enlivening help Qi Huayuan;Fructus Lycii, Fructus Crataegi, Herba Potentillae Discoloris, Fructus Anisi Stellati invigorating the liver and kidney, blood nourishing and hair;Radix Desmodii Caudati, ardisia maculosa Mez activating blood and removing stasis, logical stagnant;Cacumen Platycladi, makes newborn hair not shaken by ailment said due to cold or exposure and come off.All medicines share, and reach the purpose of blood nourishing and hair.
The prominent substantive distinguishing features of the present invention with significantly progress is:
1, the present invention prevents and treats the health promoting wine of alopecia, formed by the Chinese herbal medicine compatibility of invigorating the spleen and benefiting QI, effect of nourishing YIN and supplementing blood, the alopecias such as alopecia, puerperal alopecia, anemia alopecia and the malnutrition causing blood wind alopecia, side effects of pharmaceutical drugs all have significant curative effect, drink after health promoting wine of the present invention 30~60 days, hair restoration rate is more than 98%, with the kidney invigorating, QI invigorating, invigorate blood circulation, the effect such as YIN nourishing, strong body, be a kind of environmental protection, green health promoting wine;
2, the health promoting wine of the present invention can improve immunologic function, resisting fatigue, protect the liver, regulates the effects such as cardiovascular function, and the anti-alopecia-stopping of what is more important improves the hair quality of people, is especially suitable for middle age and drinks;
3, the health promoting wine of the present invention, drinks rear noresidue medicine, has ensured safety and the health of health promoting wine;
4, the health promoting wine of the present invention is added with syrup, aroma alcohol and, taste glycol, every day 2 times, 15-30ML is advisable every time, for heart tonifying the kidney invigorating, strengthens metabolism, defying age, resisting fatigue, benefiting QI for strengthening the superficies, weak for the deficiency of vital energy, deficiency of QI in middle-JIAO has the effect that improves significantly;
5, present ecological deterioration is serious, various diseases also emerge in an endless stream, in order to ensure the health of health, a lot of people select to strengthen the immunocompetence of oneself, the health promoting wine of the present invention from diet, and using pure natural medical material is raw material, it is equipped with pure grain rice wine and soaks refined forming, can fundamentally nurse one's health each function of health, except preventing and treating alopecia, it is also possible to strengthen body immunity.
Detailed description of the invention
The following is embodiments of the invention:
The health promoting wine of described preventing and treating alopecia, including the raw material of following parts by weight:, sugar liquid 150, rice wine 9000.
The health promoting wine of described preventing and treating alopecia, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 100, Agkistrodon ichthyosis 240, Agkistrodon Fel Serpentis 50, cock testis 50, Fructus Arctii 30, ardisia maculosa Mez 30, Cortex Tiliae omeiensis Radicis 30, Radix Desmodii Caudati 30, Fructus Foeniculi 20, Rhizoma Homalomenae 20, Cacumen Platycladi 20, Fructus Lycii 20, Fructus Crataegi 14, Herba Potentillae Discoloris 14, Fructus Anisi Stellati 12, Arillus Longan 12, Semen Armeniacae Amarum 12, sugar liquid 200, rice wine 10000.
Embodiment 1:
The health promoting wine of described preventing and treating alopecia, its production method comprises the following steps:
(1) by weight by Fructus Arctii 20, ardisia maculosa Mez 20, Cortex Tiliae omeiensis Radicis 20, Radix Desmodii Caudati 20, Fructus Foeniculi 18, Rhizoma Homalomenae 18, Cacumen Platycladi 18, Fructus Lycii 18, Fructus Crataegi 12, Herba Potentillae Discoloris 12, Fructus Anisi Stellati 10, Arillus Longan 10 and Semen Armeniacae Amarum 10, clean and remove foreign body, foreign material;
(2) by the raw material co-grinding of step (1), cross 100 mesh sieves, be placed in the container of sealing, add Carapax et Plastrum Testudinis 60, Agkistrodon ichthyosis 200, Agkistrodon Fel Serpentis 30, cock testis 30 and rice wine 8000 by weight, seal and soak 35-40 days;
(3) immersion seven days, stir 5-6 time with willow rod every day, within after seven days every 3-5 days, stir 1 time, after treating that effective ingredient is dissolved in wine, are filtrated to get filtrate A and filtering residue;
(4) taking step (3) gained filtering residue to carry out squeezing and obtain pressed liquor, then merged with pressed liquor by step (3) gained filtrate A, stand 24 hours, supernatant obtains liquor B by the filter of aperture < 2 μm;
(5) by weight sugar liquid 100 is added liquor B mixing, tinning or bottling, instantaneous sterilizing, seals, obtain the health promoting wine of described preventing and treating alopecia.
The present invention prevents and treats the health promoting wine of alopecia and is formed by the Chinese herbal medicine compatibility of invigorating the spleen and benefiting QI, effect of nourishing YIN and supplementing blood, the alopecias such as alopecia, puerperal alopecia, anemia alopecia and the malnutrition causing blood wind alopecia, side effects of pharmaceutical drugs all have significant curative effect, with the kidney invigorating, QI invigorating, invigorate blood circulation, the effect such as YIN nourishing, strong body, its drinking method is: every day 2 times, each 15-30ML.
Embodiment 2:
The health promoting wine of described preventing and treating alopecia, its production method comprises the following steps:
(1) by weight by Fructus Arctii 25, ardisia maculosa Mez 25, Cortex Tiliae omeiensis Radicis 25, Radix Desmodii Caudati 25, Fructus Foeniculi 19, Rhizoma Homalomenae 19, Cacumen Platycladi 19, Fructus Lycii 19, Fructus Crataegi 13, Herba Potentillae Discoloris 13, Fructus Anisi Stellati 11, Arillus Longan 11 and Semen Armeniacae Amarum 11, clean and remove foreign body, foreign material;
(2) by the raw material co-grinding of step (1), cross 100 mesh sieves, be placed in the container of sealing, add Carapax et Plastrum Testudinis 80, Agkistrodon ichthyosis 220, Agkistrodon Fel Serpentis 40, cock testis 40 and rice wine 9000 by weight, seal and soak 35-40 days;
(3) immersion seven days, stir 5-6 time with willow rod every day, within after seven days every 3-5 days, stir 1 time, after treating that effective ingredient is dissolved in wine, are filtrated to get filtrate A and filtering residue;
(4) taking step (3) gained filtering residue to carry out squeezing and obtain pressed liquor, then merged with pressed liquor by step (3) gained filtrate A, stand 24 hours, supernatant obtains liquor B by the filter of aperture < 2 μm;
(5) by weight sugar liquid 150 is added liquor B mixing, tinning or bottling, instantaneous sterilizing, seals, obtain the health promoting wine of described preventing and treating alopecia.
The present invention prevents and treats the health promoting wine of alopecia and is formed by the Chinese herbal medicine compatibility of invigorating the spleen and benefiting QI, effect of nourishing YIN and supplementing blood, the alopecias such as alopecia, puerperal alopecia, anemia alopecia and the malnutrition causing blood wind alopecia, side effects of pharmaceutical drugs all have significant curative effect, with the kidney invigorating, QI invigorating, invigorate blood circulation, the effect such as YIN nourishing, strong body, its drinking method is: every day 2 times, each 15-30ML.
Embodiment 3:
The health promoting wine of described preventing and treating alopecia, its production method comprises the following steps:
(1) by weight by Fructus Arctii 30, ardisia maculosa Mez 30, Cortex Tiliae omeiensis Radicis 30, Radix Desmodii Caudati 30, Fructus Foeniculi 20, Rhizoma Homalomenae 20, Cacumen Platycladi 20, Fructus Lycii 20, Fructus Crataegi 14, Herba Potentillae Discoloris 14, Fructus Anisi Stellati 12, Arillus Longan 12 and Semen Armeniacae Amarum 12, clean and remove foreign body, foreign material;
(2) by the raw material co-grinding of step (1), cross 100 mesh sieves, be placed in the container of sealing, add Carapax et Plastrum Testudinis 100, Agkistrodon ichthyosis 240, Agkistrodon Fel Serpentis 50, cock testis 50 and rice wine 10000 by weight, seal and soak 35-40 days;
(3) immersion seven days, stir 5-6 time with willow rod every day, within after seven days every 3-5 days, stir 1 time, after treating that effective ingredient is dissolved in wine, are filtrated to get filtrate A and filtering residue;
(4) taking step (3) gained filtering residue to carry out squeezing and obtain pressed liquor, then merged with pressed liquor by step (3) gained filtrate A, stand 24 hours, supernatant obtains liquor B by the filter of aperture < 2 μm;
(5) by weight sugar liquid 200 is added liquor B mixing, tinning or bottling, instantaneous sterilizing, seals, obtain the health promoting wine of described preventing and treating alopecia.
The present invention prevents and treats the health promoting wine of alopecia and is formed by the Chinese herbal medicine compatibility of invigorating the spleen and benefiting QI, effect of nourishing YIN and supplementing blood, the alopecias such as alopecia, puerperal alopecia, anemia alopecia and the malnutrition causing blood wind alopecia, side effects of pharmaceutical drugs all have significant curative effect, with the kidney invigorating, QI invigorating, invigorate blood circulation, the effect such as YIN nourishing, strong body, its drinking method is: every day 2 times, each 15-30ML.
The present invention tonifies Qi of the kidney the application effect of health preserving wine
The clinical practice of the health preserving wine of tonifying Qi of the kidney of the present invention: in March, 2013 in December ,-2015, treatment on probation to 150 hair loss patients, this crowd is carried out Continuous Observation, record symptom and change, drinking method is: every day 2 times, after meal or drinks before sleeping, 15-30ML, 20 days courses for the treatment of every time.
Criterion:
Curing: new sending out all grows, distribution density, hair thickness, the same normal hair of color and luster gently draw negative;
Effective: kainogenesis length more than 50%, there is more fine hair on birds or animals hair to become terminal hair, gently draw negative;
Effective: kainogenesis length more than 10% (including fine hair on birds or animals hair), but poor growth, gently draw negative or the positive;
Invalid: to continue to come off less than 10% or while growth without kainogenesis length or kainogenesis length.
Result is as shown in table 1:
The compliance test result preventing and treating Alopecia-treatment health-care wine taken by table 1
Number of cases 150(people)
Male's number of cases 87(people)
Women number of cases 73(people)
Cure number of cases 52(people)
Effective number of cases 60(people)
Effectively number of cases 35(people)
Invalid number of cases 3(people)
Total effective rate 98%
Therapeutic effect: cure 52 examples (35%), effective 60 examples (40%), effective 35 examples (23%), invalid 3 examples (2%), total effective rate 98%.And 3 people in invalid are after being continuing with a period of time, alopecia symptom the most all makes moderate progress, and is therefore not excluded for making result deviation because the use time is short.During use, there is malaise symptoms or side effect in no one.
Model case:
Case one: Lee so-and-so, male, 52 years old, workman, patient's alopecia was nearly more than 2 years, almost takes off light, various big hospital of once going to a doctor, and Chinese medicine is bought in market by oneself, Western medicine includes imported medicine, has spent nearly ten thousand yuan, has had no effect.Economy-combat workman person introduced later, came to go to a doctor.Take the present embodiment 1 medicated wine in June, 2013, after 1 course for the treatment of, alopecia symptom has had and has been obviously improved, after 2 courses for the treatment of, and the whole demutation of hair, restore to the original state.
Case two: Yang, 26 years old, company clerk, due to long-term overtime work, life did not had rule, and pressure is very big, and head hair follicle inflammation, hair has the most just fallen, poor effect of repeatedly seeking medical advice, and the most upon somebody's introduction, comes to go to a doctor.Take the present embodiment 2 medicated wine in February, 2014, after 2 courses for the treatment of, alopecia symptom has had and has been obviously improved, after 3 courses for the treatment of, and the whole demutation of hair, restore to the original state.
Case three: beam so-and-so, 56 years old, teacher, patient's readme was near the most over the past half year, alopecia, so that existing alopecia areata shape, the most once arrived locality and seeks medical advice, or buy medicine in free market, and the most never took effect.The present embodiment 3 medicated wine, after 2 courses for the treatment of, the whole demutation of hair is taken in August, 2014.
Case four: Zhang, 28 years old, civil servant, recalls according to patient, before 5 years, head begins to alopecia occur, within nearest 2 years, gradually increasing the weight of, hair substantially attenuates, tails off, and sends out sense greasy, during the dandruff many time few, moving substantially after forehead hairline line, both sides frontal eminence moves and becomes apparent from, head hair becomes the most rare.The most upon somebody's introduction, come to go to a doctor.Take the present embodiment 1 medicated wine in October, 2013, after 2 courses for the treatment of, alopecia symptom has had and has been obviously improved, after 3 courses for the treatment of, and the whole demutation of hair, restore to the original state.
Case five: leaf so-and-so, 23 years old, student, due to often hair dyeing, fell to be over the most substantially in front middle part position, and poor effect of repeatedly seeking medical advice the most upon somebody's introduction, comes to go to a doctor.Taking the present embodiment 2 medicated wine in JIUYUE, 2014, after 3 courses for the treatment of, alopecia symptom has had and has been obviously improved, after 5 courses for the treatment of, and the whole demutation of hair, restore to the original state.
Case six: Chen, 36 years old, company clerk, patient is more serious due to alopecia ratio, going examination in hospital to be the discovery that seborrheic alopecia, its reason is that internal asthenic fire is occured simultaneously with dampness, makes this oils and fats below corium rise to epidermis, hair follicle is blocked, block the nutrition supply of hair growth, and float to the root of hair of the shallow table of epidermis and cause coming off because taking root loosely nutrition and interrupting, toss about in bed all parts of the country and seek medical advice poor effect, the most upon somebody's introduction, come to go to a doctor.Taking the present embodiment 3 medicated wine in JIUYUE, 2014, after 2 courses for the treatment of, alopecia symptom has had and has been obviously improved, after 4 courses for the treatment of, and the whole demutation of hair, restore to the original state.

Claims (9)

1. the health promoting wine preventing and treating alopecia, it is characterized in that, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 60-100, Agkistrodon ichthyosis 200-240, Agkistrodon Fel Serpentis 30-50, cock testis 30-50, Fructus Arctii 20-30, ardisia maculosa Mez 20-30, Cortex Tiliae omeiensis Radicis 20-30, Radix Desmodii Caudati 20-30, Fructus Foeniculi 18-20, Rhizoma Homalomenae 18-20, Cacumen Platycladi 18-20, Fructus Lycii 18-20, Fructus Crataegi 12-14, Herba Potentillae Discoloris 12-14, Fructus Anisi Stellati 10-12, Arillus Longan 10-12, Semen Armeniacae Amarum 10-12, sugar liquid 100-200, rice wine 8000-10000.
Prevent and treat the health promoting wine of alopecia the most according to claim 1, it is characterized in that, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 60, Agkistrodon ichthyosis 200, Agkistrodon Fel Serpentis 30, cock testis 30, Fructus Arctii 20, ardisia maculosa Mez 20, Cortex Tiliae omeiensis Radicis 20, Radix Desmodii Caudati 20, Fructus Foeniculi 18, Rhizoma Homalomenae 18, Cacumen Platycladi 18, Fructus Lycii 18, Fructus Crataegi 12, Herba Potentillae Discoloris 12, Fructus Anisi Stellati 10, Arillus Longan 10, Semen Armeniacae Amarum 10, sugar liquid 100, rice wine 8000.
Prevent and treat the health promoting wine of alopecia the most according to claim 1, it is characterized in that, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 80, Agkistrodon ichthyosis 220, Agkistrodon Fel Serpentis 40, cock testis 40, Fructus Arctii 25, ardisia maculosa Mez 25, Cortex Tiliae omeiensis Radicis 25, Radix Desmodii Caudati 25, Fructus Foeniculi 19, Rhizoma Homalomenae 19, Cacumen Platycladi 19, Fructus Lycii 19, Fructus Crataegi 13, Herba Potentillae Discoloris 13, Fructus Anisi Stellati 11, Arillus Longan 11, Semen Armeniacae Amarum 11, sugar liquid 150, rice wine 9000.
Prevent and treat the health promoting wine of alopecia the most according to claim 1, it is characterized in that, including the raw material of following parts by weight: Carapax et Plastrum Testudinis 100, Agkistrodon ichthyosis 240, Agkistrodon Fel Serpentis 50, cock testis 50, Fructus Arctii 30, ardisia maculosa Mez 30, Cortex Tiliae omeiensis Radicis 30, Radix Desmodii Caudati 30, Fructus Foeniculi 20, Rhizoma Homalomenae 20, Cacumen Platycladi 20, Fructus Lycii 20, Fructus Crataegi 14, Herba Potentillae Discoloris 14, Fructus Anisi Stellati 12, Arillus Longan 12, Semen Armeniacae Amarum 12, sugar liquid 200, rice wine 10000.
Prevent and treat the health promoting wine of alopecia the most according to claim 1, it is characterized in that, the acquisition methods of described Agkistrodon ichthyosis and Agkistrodon Fel Serpentis is: take some Agkistrodon, and gill after slaughtering reservation Fel Serpentis, Naja ichthyosis cleaned and dries moisture, obtaining Agkistrodon ichthyosis and Agkistrodon Fel Serpentis.
Prevent and treat the health promoting wine of alopecia the most according to claim 1, it is characterised in that described cock testis is to select the testis that takes off with just opening the cock crowed, cut open after cooking, dry after obtain.
Prevent and treat the health promoting wine of alopecia the most according to claim 1, it is characterised in that described sugar liquid is to obtain after the Chinese liquor adding with crystal sugar and accounting for gross weight 2-3 times amount warms dissolving, filtration.
The most according to claim 1, prevent and treat the health promoting wine of alopecia, it is characterised in that described rice wine is with brown rice as raw material, with saccharifying enzyme, yeast for ferment agent, through adding slurry form without adjuvant steaming and decocting cultivation fermentation, distillation, alcohol content is 50 60%.
Prevent and treat the health promoting wine of alopecia the most according to claim 1, it is characterised in that its production method comprises the following steps:
(1) by Fructus Arctii 20-30, ardisia maculosa Mez 20-30, Cortex Tiliae omeiensis Radicis 20-30, Radix Desmodii Caudati 20-30, Fructus Foeniculi 18-20, Rhizoma Homalomenae 18-20, Cacumen Platycladi 18-20, Fructus Lycii 18-20, Fructus Crataegi 12-14, Herba Potentillae Discoloris 12-14, Fructus Anisi Stellati 10-12, Arillus Longan 10-12 and Semen Armeniacae Amarum 10-12, clean and remove foreign body, foreign material;
(2) by the raw material co-grinding of step (1), cross 100 mesh sieves, be placed in the container of sealing, add Carapax et Plastrum Testudinis 60-100, Agkistrodon ichthyosis 200-240, Agkistrodon Fel Serpentis 30-50, cock testis 30-50 and rice wine 8000-10000, seal and soak 35-40 days;
(3) immersion seven days, stir 5-6 time with willow rod every day, within after seven days every 3-5 days, stir 1 time, after treating that effective ingredient is dissolved in wine, are filtrated to get filtrate A and filtering residue;
(4) taking step (3) gained filtering residue to carry out squeezing and obtain pressed liquor, then merged with pressed liquor by step (3) gained filtrate A, stand 24 hours, supernatant obtains liquor B by the filter of aperture < 2 μm;
(5) sugar liquid 100-200 is added liquor B mixing, tinning or bottling, instantaneous sterilizing, seal, obtain the health promoting wine of described preventing and treating alopecia.
CN201610585677.5A 2016-07-25 2016-07-25 Alopecia-prevention health care wine and production method thereof Pending CN105950407A (en)

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