CN103550505A - Traditional Chinese medicine preparation for treating qi-yin deficiency type diabetes - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating qi-yin deficiency type diabetes. The traditional Chinese medicine preparation comprises the following main raw materials in parts by weight respectively: 18 parts of radix polygonati officinalis, 12 parts of smoked plum, 30 parts of rhizoma polygonati, 30 parts of Chinese yam, 18 parts of multiflower knotweed root, 15 parts of radix scrophulariae, 12 parts of radices trichosanthis and 12 parts of glossy privet fruit. The radix polygonati officinalis, the smoked plum, the rhizoma polygonati, the Chinese yam, the multiflower knotweed root, the radix scrophulariae, the radices trichosanthis and the glossy privet fruit are selected to be combined, so that a synergistic effect is generated among the effects of the medicines, and the effects of treating thirst, polydipsia and diuresis symptoms of the medicine are intensified. Therefore, the diabetes can be effectively treated.

Description

The Chinese medicine preparation for the treatment of Qi and Yin deficiency diabetes mellitus

Technical field

The present invention relates to a kind of Chinese medicine preparation for the treatment of Qi and Yin deficiency diabetes mellitus and, be specifically related to a kind of Chinese medicine preparation of being made by primary raw material Rhizoma Polygonati Odorati, Fructus Mume and other raw material of Chinese medicine compatibility.

Background technology

In prior art, diabetes be one group due to the metabolic disease that hyperglycemia is feature of take due to defect of insulin secretion and/or insulin action obstacle.Continue hyperglycemia and long-term metabolism disorder etc. and can cause body tissue's organ, particularly eye, kidney, cardiovascular and neural infringement and dysfunction and exhaustion.Severe patient can cause acute complications ketoacidosis and the Hyperosmotic comas such as dehydration, electrolyte disturbance and acid base imbalance.The treatment of diabetes comprises the detection of diabetes education, Diet Therapy, exercise therapy, Drug therapy, blood sugar monitoring and other cardiovascular disease risk factor and controls several aspects.Once Diabetes Mellitus Knowledge education diabetes are made a definite diagnosis, and tackle patient and carry out diabetes education, comprise the monitoring of the general knowledge of diabetes, self-blood glucose and glucose in urine.The usage of hypoglycemic medicine, the observation of untoward reaction and processing etc.And the performance of various complication and control.Diet Therapy is the primary measure of all kinds diabetes Primary Care.The principle of Diet Therapy is: control total amount of heat and body weight.Reduce fat, especially saturated fatty acid content in food, increase dietary fiber content, make the proportion of carbohydrate in food, fat and protein reasonable.Control the absorption of meals gross energy, rationally the various nutrient substance of balanced distribution.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine preparation with treatment Qi and Yin deficiency diabetes mellitus, psoriasis nummularis, geographic psoriasis, seborrheic-like psoriasis, psoriasis rupioides, chronic plumpness psoriasis, psoriasis verrucosa etc. are had to good preventive and therapeutic action.

The technical solution used in the present invention is: the Chinese medicine preparation of described treatment Qi and Yin deficiency diabetes mellitus, its primary raw material and weight portion respectively, 18 parts of Rhizoma Polygonati Odorati, 12 parts of Fructus Mumes, Rhizoma Polygonati 30,30 parts of Rhizoma Dioscoreaes, 18 parts of the Radixs Polygoni Multiflori, 15 parts of Radix Scrophulariaes, 12 parts of Radix Trichosanthis, 12 parts of Fructus Ligustri Lucidi.

The present invention selects Rhizoma Polygonati Odorati, Fructus Mume, Rhizoma Polygonati, Rhizoma Dioscoreae, the Radix Polygoni Multiflori, Radix Scrophulariae, Radix Trichosanthis, Fructus Ligustri Lucidi to combine, by these drug regimens, make each efficacy of drugs produce synergism strengthening medicine and improve Qi and Yin deficiency diabetes mellitus, thereby can effectively treat Qi and Yin deficiency diabetes mellitus.

The selected raw material of the present invention, its property of medicine and effect respectively: Rhizoma Polygonati Odorati: the dry rhizome of liliaceous plant Rhizoma Polygonati Odorati.Root stock is containing Rhizoma Polygonati Odorati mucopolysaccharide.Also contain Rhizoma Polygonati spiral shell sterol (polyspirostanol) Poa, Rhizoma Polygonati spiral shell sterol glycoside Rhizoma Polygonati furan sterol glycoside, the steroids such as Rhizoma Polygonati furan sterol glycoside Poc, Pod, P06.P07.P08 and P09.P02 and Pob have same structure, are 25-R, S three-dimensional heterogeneous mixture, and just R/S ratio is different; P03 is the extremely mixture of 25-R of Poc.Nourishing YIN and moistening the lung; Nourishing the stomach to promote the production of body fluid.Cough caused by dryness; Chronic cough; The dry throat and mouth of the cloudy liquid consumption of calentura wound; Interior-heat is quenched one's thirst; Deficiency of YIN diseases caused by exogenous pathogenic factor; Dizzy dizzy; Muscle arteries and veins spasm and pain.

Fructus Mume: another name dark plum, yellow young, the almost ripe fruit that closes the Chinese prunus mume (sieb.) sieb.et zucc. ,Gan Zhi Mei，Wei prunus mume (sieb.) sieb.et zucc. Prunus mume of rosaceae plant deciduous tree, through pyrotechnics, smoke and form.If soak night with saline Exposure to Sunlight with Armeniaca mume Sieb., after 10 days, there is bloom to form, be called bloom prunus mume (sieb.) sieb.et zucc., its effect is similar, and compatibility and incompatibility of drugs is identical.According to modern study. Armeniaca mume Sieb. or Fructus Armeniacae Mume juice.Less containing sodium containing potassium is many in Fructus Mume, therefore, need long-term taking row potassium diuretic person should eat it; Fructus Armeniacae Mume can promote enterokinesia containing catechuic acid, so the people of constipation should eat it.In Fructus Armeniacae Mume, containing multiple organic acid, be improved the effect of liver function, therefore hepatopath should eat it.Prunus mume (sieb.) sieb.et zucc. acid in Fructus Armeniacae Mume can vessel softening, postpones sclerosis of blood vessels, has anti-senility effect.

Rhizoma Polygonati: Rhizoma Polygonati rhizome is containing nicotinic acid, phlegmatic temperament, quinones.And containing polygonatum polysaccharide first, second, third (being combined into by glucose, mannose, galacturonic acid), polygonatum rhizome oligosaccharide first, second, third (being combined into by glucose and fructose).In addition, separately containing 11 seed amino acids such as lysines.Cure mainly: deficiency of YIN chronic cough; Xeropulmonary cough; Insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; Tinnitus order is dark; Early whitening of beard and hair; The empty win of body is thin; Wind favus disease.

Rhizoma Dioscoreae: [source] these product are the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.Winter, stem and leaf was excavated after withering, and cut root head, cleaned, and removed crust and fibrous root, after smoking with sulfur, dry; Also have and select loose straight dry Rhizoma Dioscoreae, put in clear water, be dipped into without the dry heart, vexed, after smoking with sulfur, trim two ends, with plank, be twisted into cylindricly, dry polishing.[nature and flavor with return through] sweet in the mouth, property is flat.Return spleen, lung, kidney channel.[function with cure mainly] spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Modern pharmacological research confirms, RHIIZOMA DIOSCOREAE fr0m Henan of China has nutritious tonifying, induce and disturb that excretion in element, enhancing human body immunity power, scheduling, QI invigorating are promoted blood circulation, relieving cough and expelling phlegm, relieving asthma etc. and to help to change, coronary artery and micro-samsara blood flow can be improved, chronic tracheitis, hat unpleasantness, angina pectoris etc. can be treated.

Radix Polygoni Multiflori: the effect removing toxic substances of Radix Polygoni Multiflori, eliminating carbuncle, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation, hyperlipemia.Radix Polygoni Multiflori Preparata: invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening; For vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, hyperlipemia.Pharmacological evaluation proves, Radix Polygoni Multiflori Preparata can promote erythropoiesis, promotes hemopoietic function, strengthen immunologic function, reduce blood glucose, cardiac muscle is had to excitation, energy decreased heart rate, increase coronary artery blood flow, can reduce cholesterol, alleviate atherosclerosis, protect the liver, slow down aging, and have the effect that promotes that intestinal tube is wriggled.

The Rhizoma Atractylodis Macrocephalae: Rhizoma Atractylodis Macrocephalae perennial herb, with rhizome, be used as medicine, there is multinomial medicinal function.[meridian distribution of property and flavor] is bitter, sweet, temperature.Return spleen, stomach warp.Effect: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.

Radix Codonopsis: be the general designation of plant Radix Codonopsis and Chinese crude drug.Codonopsis plant.Chinese medicine Radix Codonopsis is campanulaceae herbaceos perennial Radix Codonopsis, element flower Radix Codonopsis, radix codonpsis tangshen and the root that belongs to various plants together thereof.There is invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Modern study, Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and Alkaloid, has enhancing immunity, blood vessel dilating, blood pressure lowering, improves microcirculation, strengthens the effects such as hemopoietic function.In addition leukopenia chemotherapy radiotherapy being caused has castering action.

Radix Scrophulariae: the dry root of the plant Radix Scrophulariae Scrophularia ningpoensis Hemsl. of section.Application branch of learning: Chinese medicine and pharmacy (one-level subject); Chinese materia medica (secondary subject); Chinese medicine (secondary subject) Chinese medicine name, cures mainly: epidemic febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue, puckery dim-sighted, the laryngopharynx swelling and pain of constipation, order, scrofula sucutaneous nodule, skin sore are not hindered in awake, Tianjin to send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency.

Radix Trichosanthis: the dry root of cucurbitaceous plant Fructus Trichosanthis Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms.Application branch of learning: Chinese medicine and pharmacy (one-level subject); Chinese materia medica (secondary subject); Chinese medicine (secondary subject) Radix Trichosanthis is the root of cucurbitaceous plant Chinese juniper beach wormwood, is a kind of Chinese medicine, is clearing away heat-fire class medicine, and its concrete effect is clearing away heat-fire, promoting the production of body fluid to quench thirst, evacuation of pus detumescence.Cure mainly: control calentura thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity.For treatment diabetes, conventional it and drugs for nourishing yin are used in conjunction with, to reach the effect for the treatment of both the principal and secondary aspects of a disease.

Fructus Ligustri Lucidi: Fructus Ligustri Lucidi is the fruit of Oleaceae Ligustrum plant Fructus Ligustri Lucidi.Odorless, sweet in the mouth, micro-bitterness.Effect: tonifying liver kidney yin, crow must improving eyesight, and modern medicine study thinks that the effect that Fructus Ligustri Lucidi can suppress helicobacter pylori can treat gastropathy, also has and suppresses purine abnormal metabolism for the treatment of gout and hyperuricemia.Cure mainly: for the hepatic and renal YIN deficiency, soreness of waist tinnitus, early whitening of beard and hair; Unseeing, poor vision; Fever due to yin deficiency, gastropathy and gout and and hyperuricemia.

Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.For example these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can be by these crude drug together decocting, then concentrated decocting liquid is taken, or concentrated decocting liquid is condensed into cream is processed into pill and takes; In order to make each raw material of this medicine bring into play better drug effect, for certain crude drug, carry out special extraction, as ethanol extraction, these can not be for limiting the scope of the invention.Active component of the present invention can add various conventional adjuvant required while preparing different dosage form, as disintegrating agent, lubricant, binding agent etc. are prepared into any conventional peroral dosage form with conventional method of Chinese medicinal, as pill, powder, tablet, capsule, oral liquid etc.

Medicine of the present invention has tonifying liver kidney yin, and dampness diuretic effect, is used for the treatment of Qi and Yin deficiency diabetes mellitus.So far, still do not find report and the application of relevant Chinese medicine preparation of the present invention.The inventor, through research repeatedly, and by the checking repeatedly of clinical trial, has finally found the endo-medicine that has better curative effect, thereby has completed the present invention.

Specific implementation method

The Chinese medicine preparation of described treatment Qi and Yin deficiency diabetes mellitus: its primary raw material and weight portion respectively, 18 parts of Rhizoma Polygonati Odorati, 12 parts of Fructus Mumes, Rhizoma Polygonati 30,30 parts of Rhizoma Dioscoreaes, 18 parts of the Radixs Polygoni Multiflori, 15 parts of Radix Scrophulariaes, 12 parts of Radix Trichosanthis, 12 parts of Fructus Ligustri Lucidi.

Claims (1)

1. a Chinese medicine preparation for the treatment of Qi and Yin deficiency diabetes mellitus, is characterized in that: its primary raw material and weight portion difference: 18 parts of Rhizoma Polygonati Odorati, 12 parts of Fructus Mumes, Rhizoma Polygonati 30,30 parts of Rhizoma Dioscoreaes, 18 parts of the Radixs Polygoni Multiflori, 15 parts of Radix Scrophulariaes, 12 parts of Radix Trichosanthis, 12 parts of Fructus Ligustri Lucidi.