CN105148168A - Traditional Chinese medicine preparation for treating diabetes mellitus - Google Patents

Traditional Chinese medicine preparation for treating diabetes mellitus Download PDF

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CN105148168A
CN105148168A CN201510673768.XA CN201510673768A CN105148168A CN 105148168 A CN105148168 A CN 105148168A CN 201510673768 A CN201510673768 A CN 201510673768A CN 105148168 A CN105148168 A CN 105148168A
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rhizoma
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孙华堂
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Abstract

The invention relates to a traditional Chinese medicine preparation for treating diabetes mellitus. The preparation is prepared from radix polygonati officinalis, Chinese yam, corn stigma, endothelium corneum gigeriae galli, pollen, dried sophora flower, radix polygoni multiflori, licorice root, purslane, fructus lycii, fructus mume, poria cocos, fructus amomi, rhizoma alismatis, polygonatum kingianum, radix scrophulariae, radix paeoniae alba, Sichuan rhizoma coptidis, edestan, dandelion, bamboo leaves, esliptae herba, fomes japonica and reed rhizome. Based on the principle of treating both symptom and root causes and the like in the traditional Chinese medicine, the preparation has the effects of tonifying qi, nourishing yin, clearing heat, moistening dryness, promoting production of body fluid, arresting thirsty, tonifying kidneys, regulating middle warmer and the like. The preparation is convenient and simple to take, has a good effect, can be used for effectively controlling blood glucose and urine glucose, remarkably recovering energy, constitution and other functions, and remarkably reducing glycated serum protein, remarkably improving sugar tolerance and promoting insulin secretion under a high-glucose state, and has a certain repairing effect on injury of insulin tissues. The insulin release of a diabetes mellitus patient shows a certain rising trend after treatment, so that the aim of effectively treating and controlling diabetes mellitus can be achieved.

Description

A kind of Chinese medicine preparation for the treatment of diabetes
Technical field
The invention belongs to the field of Chinese medicines, a kind ofly specifically can treat a kind of Chinese medicine preparation for the treatment of diabetes.
Background technology
Diabetes are one of large difficult disease in the world three.Diabetes are one group take hyperglycemia as the metabolic disease of feature caused by defect of insulin secretion and/or insulin action obstacle.Persistent high blood sugar and long-term metabolic are disorderly etc. can cause body tissue's organ, particularly eye, kidney, cardiovascular and neural infringement and dysfunction thereof and exhaustion.Severe patient can cause dehydration, the acute complications such as electrolyte disturbance and acid base imbalance ketoacidosis and Hyperosmotic coma.The symptom of diabetes can be divided into two large classes: a large class is the performance relevant with metabolism disorder, especially relevant with hyperglycemia polyuria, polydipsia, polyphagia and become thin, be more common in type 1 diabetes, type 2 diabetes mellitus is normal not fairly obvious or only have part to show, another large class is various acute, the performance of chronic complicating diseases.
At present, clinical treatment Chinese medicine and western medicine used reaches tens of kinds, but owing to also not having substantial breakthrough so far to diabetes pathology, etiological study, treatment diabetes are still in and control blood glucose, glucose in urine increases the stage and the conceptual phase of prevention syndrome.In addition, patient's long-term taking Western medicine, can bring side effect to organs such as kidney,liver,spleen, the heart, stomaches.And domestic current its curative effect of various Chinese medicine preparation is also in control blood glucose, glucose in urine increases the stage, obtain convictive scientific basis without any a kind of medicine has repair to human pancreas tissue injury.
Summary of the invention
The problem to be solved in the present invention is for above problem, provides the Chinese medicine preparation of the treatment diabetes that a kind of cure rate is high, side effect is little, relapse rate is low.
For solving the problem, the technical solution adopted in the present invention is:
Treat a Chinese medicine preparation for diabetes, it is characterized in that: described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 10 ~ 20 grams, Rhizoma Dioscoreae 5 ~ 10 grams, Stigma Maydis 1 ~ 3 gram, Endothelium Corneum Gigeriae Galli 5 ~ 15 grams, pollen 10 ~ 20 grams, 1 ~ 5 gram, dry Flos Sophorae, the Radix Polygoni Multiflori 10 ~ 20 grams, 10 ~ 20 grams, Radix Glycyrrhizae, Herba Portulacae 5 ~ 20 grams, Fructus Lycii 10 ~ 30 grams, Fructus Mume 5 ~ 15 grams, 10 ~ 20 grams, Poria, Fructus Amomi 5 ~ 10 grams, Rhizoma Alismatis 1 ~ 5 gram, Rhizoma Polygonati 10 ~ 30 grams, Radix Scrophulariae 5 ~ 15 grams, the Radix Paeoniae Alba 10 ~ 20 grams, Rhizoma Coptidis 5 ~ 10 grams, Fructus Cannabis 5 ~ 20 grams, Herba Taraxaci 10 ~ 15 grams, 10 ~ 20 grams, Folium Bambusae, Herba Ecliptae 5 ~ 15 grams, Ganoderma sinense Zhao Xu et Zhang 10 ~ 20 grams, Rhizoma Phragmitis 5 ~ 15 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 10 grams, 1 gram, dry Flos Sophorae, the Radix Polygoni Multiflori 10 grams, 10 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 1 gram, Rhizoma Polygonati 10 grams, Radix Scrophulariae 5 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 10 grams, Folium Bambusae, Herba Ecliptae 5 grams, Ganoderma sinense Zhao Xu et Zhang 10 grams, Rhizoma Phragmitis 5 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 20 grams, Rhizoma Dioscoreae 10 grams, Stigma Maydis 3 grams, Endothelium Corneum Gigeriae Galli 15 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 20 grams, Fructus Lycii 30 grams, Fructus Mume 15 grams, 20 grams, Poria, Fructus Amomi 10 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Coptidis 10 grams, Fructus Cannabis 20 grams, Herba Taraxaci 15 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 15 grams, Rhizoma Dioscoreae 7 grams, Stigma Maydis 2 grams, Endothelium Corneum Gigeriae Galli 10 grams, pollen 15 grams, 3 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 15 grams, 15 grams, Radix Glycyrrhizae, Herba Portulacae 12 grams, Fructus Lycii 20 grams, Fructus Mume 10 grams, 15 grams, Poria, Fructus Amomi 8 grams, Rhizoma Alismatis 3 grams, Rhizoma Polygonati 20 grams, Radix Scrophulariae 10 grams, the Radix Paeoniae Alba 15 grams, Rhizoma Coptidis 8 grams, Fructus Cannabis 13 grams, Herba Taraxaci 13 grams, 15 grams, Folium Bambusae, Herba Ecliptae 10 grams, Ganoderma sinense Zhao Xu et Zhang 15 grams, Rhizoma Phragmitis 10 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 10 grams, 1 gram, dry Flos Sophorae, the Radix Polygoni Multiflori 10 grams, 10 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Coptidis 10 grams, Fructus Cannabis 20 grams, Herba Taraxaci 15 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 20 grams, Rhizoma Dioscoreae 10 grams, Stigma Maydis 3 grams, Endothelium Corneum Gigeriae Galli 15 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 20 grams, Fructus Lycii 30 grams, Fructus Mume 15 grams, 20 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 1 gram, Rhizoma Polygonati 10 grams, Radix Scrophulariae 5 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 10 grams, Folium Bambusae, Herba Ecliptae 5 grams, Ganoderma sinense Zhao Xu et Zhang 10 grams, Rhizoma Phragmitis 5 grams.
As a kind of prioritization scheme:
Described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 10 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
Wherein:
Rhizoma Polygonati Odorati sweet in the mouth, property is put down, attach to the lung and stomach meridians, there is YIN nourishing, lung moistening, nourishing the stomach, yin nourishing, heat clearing away, promote the production of body fluid, the kidney invigorating, the effect such as to quench the thirst.Rhizoma Polygonati Odorati improves phagocytic percentage and the phagocytic index of macrophage, promote interferon synthesis, suppress growth of bacillus tubercle, blood sugar lowering, blood fat reducing, alleviation atherosclerotic plaque to be formed, make peripheral blood vessel and coronary dilation, extend hypoxia endurance time, heart tonifying, antioxidation, the anti-ageing effect of waiting for a long time.Also has the effect of similar adrenocortical hormone sample.There is significant inhibitory action to the hyperglycemia that epinephrine causes, also have inhibitory action to the hyperglycemia that glucose, alloxan cause.
Rhizoma Dioscoreae sweet in the mouth, property is put down, return spleen, lung, kidney channel, there is spleen reinforcing, nourishing the stomach, QI invigorating, yin nourishing, promote the production of body fluid, lung benefiting, the kidney invigorating, arresting seminal emission, heat clearing away, the effect such as to quench one's thirst.Can be used for treating diabetes, is the dietetic therapy good merchantable brand of diabetes patient.
Stigma Maydis sweet in the mouth, slightly warm in nature, returns bladder, liver, gallbladder meridian, there is diuresis, expel the heat-evil, suppressing the hyperactive liver, function of gallbladder promoting, the kidney invigorating and in, QI invigorating, the effect such as to promote the production of body fluid.The fermentation preparation of Stigma Maydis has obvious hypoglycemic activity.Water decoction gavage has significant therapeutic effect to the diabetes caused by alloxan, also has obvious hypoglycemic activity, but present obvious dose-effect relationship to the hyperglycemia that glucose, epinephrine cause.But have no significant effect normal arterial pressure, prompting Stigma Maydis may have the effect of two flesh class hypoglycemic medicine.
Endothelium Corneum Gigeriae Galli sweet in the mouth, cold in nature, return spleen, stomach, small intestinal, urinary bladder channel, have help digestion, stomach invigorating, aid digestion, arresting seminal emission, only something lost, QI invigorating, yin nourishing, promote the production of body fluid, the effect such as to quench the thirst.
Pollen sweet in the mouth, property is put down, and returns kidney, kidney, stomach, lung meridian, have antipyretic, quench the thirst, promote the production of body fluid, QI invigorating, yin nourishing, spleen invigorating, the effect such as the kidney invigorating.Pollen can be reduced to the hypertension of overweight people, hyperglycemia normally.
Dry Flos Sophorae bitter in the mouth, cold nature, returns liver, lung, the heart, large intestine channel, there is QI invigorating, yin nourishing, promote the production of body fluid, heat clearing away, quench the thirst, moisturize, the effect such as the kidney invigorating.
Radix Polygoni Multiflori bitter in the mouth, slightly warm in nature, returns liver, kidney channel, have nourish blood, YIN nourishing, intestine moistening, relieving constipation, heat clearing away, QI invigorating, the effect such as the kidney invigorating.After oral decoct, in 30-60 minute, the rising of blood glucose amount reaches topnotch, and then reduce gradually, after 6 hours, blood glucose amount is lower by 0.03% than normally.
Radix Glycyrrhizae sweet in the mouth, property is put down, and returns spleen, stomach, lung meridian, has the effects such as QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription.
Herba Portulacae sour in the mouth, cold in nature, GUIXIN, liver, spleen, large intestine channel, there is heat clearing away, removing toxic substances, diuretic, dry, loose blood, detumescence, yin nourishing, promote the production of body fluid, the effect such as to quench the thirst.Norepinephrine energy in Herba Portulacae promotes insulin secretion, regulates carbohydrate metabolism in human body, has the effect reducing blood sugar concentration, keep glucostasis, has certain auxiliary therapeutic action to diabetes.
Fructus Lycii sweet in the mouth, property is put down, and returns kidney, liver, heart channel, has tonifying liver, kidney tonifying, QI invigorating, yin nourishing, promotes the production of body fluid, quenches the thirst, the effect such as heat clearing away.Fructus Lycii extract significantly and lastingly can reduce blood glucose, increase carbohydrate tolerance, and toxicity is less.
Fructus Mume sour in the mouth, property is put down, return liver, spleen, lung, large intestine channel, there is heat clearing away, astringe the lung, astringing intestine to stop diarrhea, promote the production of body fluid, relieving colic caused by ascaris, quench the thirst, QI invigorating, the effect such as yin nourishing.Fructus Mume can make " more than three " symptom improve, and blood glucose, glucose in urine can significantly decline.
Poria sweet in the mouth, property is put down, GUIXIN, lung, spleen, kidney channel, has QI invigorating, yin nourishing, heat clearing away, moisturizes, promotes the production of body fluid, quenches the thirst, the effect such as the kidney invigorating.
Fructus Amomi acrid in the mouth, warm in nature, return spleen, stomach, kidney channel, effects such as there is removing dampness, appetizing, warming the spleen, antidiarrheal, regulate the flow of vital energy, be antiabortive.
Rhizoma Alismatis sweet in the mouth, cold in nature, return kidney, urinary bladder channel, there is QI invigorating, heat clearing away, moisturize, promote the production of body fluid, quench the thirst, the effect such as the kidney invigorating.Rhizoma Alismatis has slight hypoglycemic activity.
Rhizoma Polygonati sweet in the mouth, property is put down, and returns liver,kidney,spleen warp, has the effects such as nourishing kidney, lung moistening, spleen reinforcing, QI invigorating, heat clearing away, yin nourishing.Originally Rhizoma Polygonati extractum per os gives blood sugar content normally, gradually increases, then reduces, the temporary increase of this blood glucose amount may owing to wherein containing caused by carbohydrate, blood glucose amount increment rate and action effective all to give Rhizoma Polygonati extractum amount and be directly proportional. the blood glucose that Rhizoma Polygonati extractum causes adrenalin hydrochloride is too high, in remarkable inhibitory action. within after Rhizoma Polygonati methanolic extract lumbar injection 4 hours, the blood glucose that normal and streptozotocin bring out is raised, has the effect that its blood glucose is reduced.Rhizoma Polygonati methanolic extract can raise, so think that its blood sugar reducing function may be relevant with the function of its suppression glycogen zymolysis system the blood glucose caused by antiadrenergic drug significantly.
Radix Scrophulariae bitter in the mouth, cold nature, returns lung, stomach, kidney channel, has the effects such as heat clearing away, removing heat from blood, pathogenic fire purging, removing toxic substances, YIN nourishing, the kidney invigorating.Radix Scrophulariae fluid extract can make blood glucose slightly reduce.
Radix Paeoniae Alba bitter in the mouth, property is put down, and returns liver, spleen channel, has the kidney invigorating, QI invigorating and blood, promotes the production of body fluid, quenches the thirst, heat clearing away, yin nourishing, the effect such as to moisturize.
Rhizoma Coptidis bitter in the mouth, cold in nature, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel, have the effects such as heat clearing away, dampness, pathogenic fire purging, removing toxic substances, the kidney invigorating, QI invigorating, yin nourishing.
Fructus Cannabis sweet in the mouth, property is put down, and returns spleen, stomach, large intestine channel, has the effects such as loosening bowel to relieve constipation, nourishing, heat clearing away, the kidney invigorating, QI invigorating.On the impact of serum cholesterol, show according to body weight and serum cholesterol concentration result of the test, Fructus Cannabis has the effect obviously stoping serum cholesterol to raise.
Herba Taraxaci mildly bitter flavor, cold in nature, return liver, gallbladder, heart channel, there is heat clearing away, removing toxic substances, detumescence, eliminating stagnation, moisturize, QI invigorating, yin nourishing, promote the production of body fluid, the kidney invigorating and medium effect.
Folium Bambusae sweet in the mouth, property Great Cold, GUIXIN, lung, gallbladder, stomach warp, there is QI invigorating, heat clearing away, moisturize, the kidney invigorating, yin nourishing, quench the thirst, promote the production of body fluid, the effect such as removing toxic substances.Research shows; Folium Bambosae extract effective ingredient comprises flavone, phenolic ketone, anthraquinone, lactone, polysaccharide, aminoacid, trace element etc., has excellent free radical resisting, defying age, resisting fatigue, blood sugar lowering, blood fat reducing, prevention cardiovascular and cerebrovascular disease, the liver protecting, expansion blood capillary, dredging microcirculation, activation brain, promotes memory, improving water flood, anticancer, beautifies the effects such as skin.
Herba Ecliptae sour in the mouth, property is put down, return kidney, spleen, stomach warp, there is heat clearing away, moisturize, QI invigorating, yin nourishing, promote the production of body fluid, the effect such as to quench the thirst.
Ganoderma sinense Zhao Xu et Zhang sweet in the mouth, warm in nature, GUIXIN, kidney, lung, stomach warp, there is QI invigorating, yin nourishing, the kidney invigorating, promote the production of body fluid, quench the thirst, heat clearing away, the effect such as removing toxic substances.Ganoderma sinense Zhao Xu et Zhang not only has direct hypoglycemic activity, and share can increase curative effect with former hypoglycemic drug, prevents or alleviates complication.When blood glucose maintain normal and stable, the dosage of the former blood sugar lowering that can cut down according to the circumstance as the case may be, to reduce the untoward reaction of medicine.The hepatoprotective effect that Ganoderma sinense Zhao Xu et Zhang itself has also can alleviate or prevent some oral hypoglycaemic medicines to the infringement of liver.
The principle of Ganoderma sinense Zhao Xu et Zhang blood sugar lowering is owing to promoting the utilization of tissue to sugar.Insulin can be replaced after taking Ganoderma and suppress disengaging of fatty acid, the symptom such as blood glucose, glucose in urine can be improved.Water soluble polysaccharide in Ganoderma, can alleviate the occurring degree of non-insulin-dependent diabetes mellitus.
Rhizoma Phragmitis sweet in the mouth, cold in nature, attach to the lung and stomach meridians, have promote the production of body fluid, heat clearing away, relieving restlessness, diuresis, the kidney invigorating, QI invigorating, the effect such as yin nourishing.
The present invention, based on principles such as traditional Chinese medical science treating both the principal and secondary aspects of a disease, has supplementing QI and nourishing YIN, clearing heat and moistening dryness, promoting the production of body fluid to quench thirst, the kidney invigorating and medium effect.Taking convenience of the present invention, simple, effective, not only blood glucose, glucose in urine are effectively controlled, and the recovery of the function such as energy, muscle power is also quite remarkable, and glycated serum protein has obvious decline.Can carbohydrate tolerance be significantly improved, also can promote insulin secretion under high sugared state; Certain repair is had to the damage of insulin tissue.Certain increase trend is had to the insulin releasing of diabetics after treatment.Thus reach the object that diabetes are effectively treated and controlled.
Manufacture method of the present invention:
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Be ground into end after above-mentioned Chinese medicine can mix by tablet, powder, pill or capsule by weight as made, make tablet, powder, pill or capsule.
Instructions of taking: every day potion, every day three times, taking half an hour after meal, seven days is a course for the treatment of.
For investigating clinical efficacy and the safety of medicine of the present invention further, we have selected the treatment curative effect of 200 routine diabeticss to medicine of the present invention and carry out clinical trial.
Select the standard of case:
Diabetes clinical manifestation: type 1 diabetes is mainly in teenager, onset is anxious, and symptom is obvious and heavy; Type 2 diabetes mellitus is more common in adult and the old people of more than 40 years old, and onset is slow, and symptom is lighter.1, polyuria, after blood glucose raises, a large amount of glucose is discharged from kidney, causes osmotic diuresis and polyuria.Every day, urine volume can reach 2-10L.2, polydipsia, thirsty because of polyuria dehydration.3, polyphagia, is excreted because glucose can not be made full use of by body, and body heat source is not enough, and patient often feels hungry, causes easy hungry polyphagia.4, become thin, peripheral tissues is to glucose utilization disorders, and fat, breaks down proteins increase, and metabolism is negative nitrogen balance, and thus patient becomes thin gradually, fatigue and weak, in addition dehydration, and body weight obviously alleviates.
All patients with above symptom are all as the standard of case selection.
Diagnostic criteria:
Fasting glucose >=7.0 mM/l; Remove Diabetic Acute complication and the heart, Liver and kidney function exhaustion, infection and merge other endocrinopathy.
Diabetic symptom adds following any one: random time blood glucose >=11.1 mM/l or fasting glucose >=7.0 mM/l.
Therapeutic scheme:
Rear oral administration solution decocted by the oral medicine of the present invention of case, and potion on the one three times on the one, is taken after meal half an hour, within seven days, is a course for the treatment of, two months statistics therapeutic outcomes.
Criterion of therapeutical effect:
Clinical cure: symptom and sign all disappear, recovers normal, and hemorheology 5, fibrinolytic system 2 recover normal, fasting glucose≤110mg/dl, twenty-four-hour urine sugar≤5g;
Clinical effective: symptom and sign disappear substantially, hemorheology 5, fibrinolytic system 2 obviously improve, fasting glucose≤110mg/dl, twenty-four-hour urine sugar≤5g;
Effectively clinical: symptom and sign obviously alleviate, hemorheology 5, fibrinolytic system 2 improve, fasting glucose≤150mg/dl, twenty-four-hour urine sugar≤10g;
Invalid: without any improvement through treatment symptom, even have and increase the weight of trend.
Conclusion:
Through adding up 200 routine diabetic therapy, clinical cure 139 example, clinical effective 41 examples, clinical effective rate 16 example, invalid 4 examples; Total effective rate reaches 98%.And have good long-term effect.Any side effect is not found during medication.Can change the clinical symptoms of patient, palliate the agonizing sufferings, life-saving, drug safety, stable curative effect, be the active drug for the treatment of diabetes and complication thereof.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of diabetes, described Chinese medicine preparation is made up of Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 10 grams, 1 gram, dry Flos Sophorae, the Radix Polygoni Multiflori 10 grams, 10 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 1 gram, Rhizoma Polygonati 10 grams, Radix Scrophulariae 5 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 10 grams, Folium Bambusae, Herba Ecliptae 5 grams, Ganoderma sinense Zhao Xu et Zhang 10 grams, Rhizoma Phragmitis 5 grams.
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Every day, potion, every day three times, took after meal half an hour, within seven days, was a course for the treatment of, certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of diabetes, described Chinese medicine preparation is made up of Rhizoma Polygonati Odorati 20 grams, Rhizoma Dioscoreae 10 grams, Stigma Maydis 3 grams, Endothelium Corneum Gigeriae Galli 15 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 20 grams, Fructus Lycii 30 grams, Fructus Mume 15 grams, 20 grams, Poria, Fructus Amomi 10 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Coptidis 10 grams, Fructus Cannabis 20 grams, Herba Taraxaci 15 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Every day, potion, every day three times, took after meal half an hour, within seven days, was a course for the treatment of, certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of diabetes, described Chinese medicine preparation is made up of Rhizoma Polygonati Odorati 15 grams, Rhizoma Dioscoreae 7 grams, Stigma Maydis 2 grams, Endothelium Corneum Gigeriae Galli 10 grams, pollen 15 grams, 3 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 15 grams, 15 grams, Radix Glycyrrhizae, Herba Portulacae 12 grams, Fructus Lycii 20 grams, Fructus Mume 10 grams, 15 grams, Poria, Fructus Amomi 8 grams, Rhizoma Alismatis 3 grams, Rhizoma Polygonati 20 grams, Radix Scrophulariae 10 grams, the Radix Paeoniae Alba 15 grams, Rhizoma Coptidis 8 grams, Fructus Cannabis 13 grams, Herba Taraxaci 13 grams, 15 grams, Folium Bambusae, Herba Ecliptae 10 grams, Ganoderma sinense Zhao Xu et Zhang 15 grams, Rhizoma Phragmitis 10 grams.
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Every day, potion, every day three times, took after meal half an hour, within seven days, was a course for the treatment of, certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice.
Embodiment 4: a kind of Chinese medicine preparation for the treatment of diabetes, described Chinese medicine preparation is made up of Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 10 grams, 1 gram, dry Flos Sophorae, the Radix Polygoni Multiflori 10 grams, 10 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Coptidis 10 grams, Fructus Cannabis 20 grams, Herba Taraxaci 15 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Every day, potion, every day three times, took after meal half an hour, within seven days, was a course for the treatment of, certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice.
Embodiment 5: a kind of Chinese medicine preparation for the treatment of diabetes, described Chinese medicine preparation is made up of Rhizoma Polygonati Odorati 20 grams, Rhizoma Dioscoreae 10 grams, Stigma Maydis 3 grams, Endothelium Corneum Gigeriae Galli 15 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 20 grams, Fructus Lycii 30 grams, Fructus Mume 15 grams, 20 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 1 gram, Rhizoma Polygonati 10 grams, Radix Scrophulariae 5 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 10 grams, Folium Bambusae, Herba Ecliptae 5 grams, Ganoderma sinense Zhao Xu et Zhang 10 grams, Rhizoma Phragmitis 5 grams.
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Every day, potion, every day three times, took after meal half an hour, within seven days, was a course for the treatment of, certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice.
Embodiment 6: a kind of Chinese medicine preparation for the treatment of diabetes, described Chinese medicine preparation is made up of Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 10 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
After being mixed by weight by above-mentioned Chinese medicine, add decocting to hour, filtering medicinal residues, obtain oral liquid.Every day, potion, every day three times, took after meal half an hour, within seven days, was a course for the treatment of, certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice.
Some patients healing case is as follows:
Wang certain, man, 64 years old, there is diabetic history 6 years, and with multiple complications, existing to sustain life with insulin, patient take medicine of the present invention after one month blood glucose start steady decline, complication is alleviated to some extent, blood sugar recovery is normal after two months, and impaired islet function is restored, and patient is energetic, blood fat, blood pressure become stable, and patient reduces hypoglycemic medicine gradually.
Revive certain, man, 41 years old, there is diabetic history 2 years, with thirsty polydipsia, frequent micturition, hunger, tired weak, take medicine of the present invention after one month blood glucose start steady decline, thirsty polydipsia after month, frequent micturition, hunger, the tired symptom such as weak are alleviated to some extent, blood sugar recovery is normal after two months, subjective symptoms disappear, liver function, renal function be improved significantly, after three months body immunity improve, quality of life obviously improves, and impaired islet function is restored.
Zhao, female, 28 years old, blood glucose of having a medical check-up when conceived six months was low, after suffer from gestational diabetes, take medicine of the present invention after one month blood glucose substantially recover normal, patient mental is full after two months, full of physical strength, and the islet function of damage is restored.

Claims (7)

1. treat a Chinese medicine preparation for diabetes, it is characterized in that: described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 10 ~ 20 grams, Rhizoma Dioscoreae 5 ~ 10 grams, Stigma Maydis 1 ~ 3 gram, Endothelium Corneum Gigeriae Galli 5 ~ 15 grams, pollen 10 ~ 20 grams, 1 ~ 5 gram, dry Flos Sophorae, the Radix Polygoni Multiflori 10 ~ 20 grams, 10 ~ 20 grams, Radix Glycyrrhizae, Herba Portulacae 5 ~ 20 grams, Fructus Lycii 10 ~ 30 grams, Fructus Mume 5 ~ 15 grams, 10 ~ 20 grams, Poria, Fructus Amomi 5 ~ 10 grams, Rhizoma Alismatis 1 ~ 5 gram, Rhizoma Polygonati 10 ~ 30 grams, Radix Scrophulariae 5 ~ 15 grams, the Radix Paeoniae Alba 10 ~ 20 grams, Rhizoma Coptidis 5 ~ 10 grams, Fructus Cannabis 5 ~ 20 grams, Herba Taraxaci 10 ~ 15 grams, 10 ~ 20 grams, Folium Bambusae, Herba Ecliptae 5 ~ 15 grams, Ganoderma sinense Zhao Xu et Zhang 10 ~ 20 grams, Rhizoma Phragmitis 5 ~ 15 grams.
2. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 10 grams, 1 gram, dry Flos Sophorae, the Radix Polygoni Multiflori 10 grams, 10 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 1 gram, Rhizoma Polygonati 10 grams, Radix Scrophulariae 5 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 10 grams, Folium Bambusae, Herba Ecliptae 5 grams, Ganoderma sinense Zhao Xu et Zhang 10 grams, Rhizoma Phragmitis 5 grams.
3. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 20 grams, Rhizoma Dioscoreae 10 grams, Stigma Maydis 3 grams, Endothelium Corneum Gigeriae Galli 15 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 20 grams, Fructus Lycii 30 grams, Fructus Mume 15 grams, 20 grams, Poria, Fructus Amomi 10 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Coptidis 10 grams, Fructus Cannabis 20 grams, Herba Taraxaci 15 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
4. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 15 grams, Rhizoma Dioscoreae 7 grams, Stigma Maydis 2 grams, Endothelium Corneum Gigeriae Galli 10 grams, pollen 15 grams, 3 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 15 grams, 15 grams, Radix Glycyrrhizae, Herba Portulacae 12 grams, Fructus Lycii 20 grams, Fructus Mume 10 grams, 15 grams, Poria, Fructus Amomi 8 grams, Rhizoma Alismatis 3 grams, Rhizoma Polygonati 20 grams, Radix Scrophulariae 10 grams, the Radix Paeoniae Alba 15 grams, Rhizoma Coptidis 8 grams, Fructus Cannabis 13 grams, Herba Taraxaci 13 grams, 15 grams, Folium Bambusae, Herba Ecliptae 10 grams, Ganoderma sinense Zhao Xu et Zhang 15 grams, Rhizoma Phragmitis 10 grams.
5. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 10 grams, 1 gram, dry Flos Sophorae, the Radix Polygoni Multiflori 10 grams, 10 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 20 grams, Rhizoma Coptidis 10 grams, Fructus Cannabis 20 grams, Herba Taraxaci 15 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
6. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 20 grams, Rhizoma Dioscoreae 10 grams, Stigma Maydis 3 grams, Endothelium Corneum Gigeriae Galli 15 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 20 grams, Fructus Lycii 30 grams, Fructus Mume 15 grams, 20 grams, Poria, Fructus Amomi 5 grams, Rhizoma Alismatis 1 gram, Rhizoma Polygonati 10 grams, Radix Scrophulariae 5 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 10 grams, Folium Bambusae, Herba Ecliptae 5 grams, Ganoderma sinense Zhao Xu et Zhang 10 grams, Rhizoma Phragmitis 5 grams.
7. a kind of Chinese medicine preparation for the treatment of diabetes according to claim 1, is characterized in that: described Chinese medicine preparation is made up of by weight following raw materials according:
Rhizoma Polygonati Odorati 10 grams, Rhizoma Dioscoreae 5 grams, Stigma Maydis 1 gram, Endothelium Corneum Gigeriae Galli 5 grams, pollen 20 grams, 5 grams, dry Flos Sophorae, the Radix Polygoni Multiflori 20 grams, 20 grams, Radix Glycyrrhizae, Herba Portulacae 5 grams, Fructus Lycii 10 grams, Fructus Mume 5 grams, 10 grams, Poria, Fructus Amomi 10 grams, Rhizoma Alismatis 5 grams, Rhizoma Polygonati 30 grams, Radix Scrophulariae 15 grams, the Radix Paeoniae Alba 10 grams, Rhizoma Coptidis 5 grams, Fructus Cannabis 5 grams, Herba Taraxaci 10 grams, 20 grams, Folium Bambusae, Herba Ecliptae 15 grams, Ganoderma sinense Zhao Xu et Zhang 20 grams, Rhizoma Phragmitis 15 grams.
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Publication number Priority date Publication date Assignee Title
CN1113146A (en) * 1994-03-08 1995-12-13 哈尔滨中药三厂 Prescription of preparation for curing diabetes
CN103055176A (en) * 2012-12-29 2013-04-24 王慎田 Traditional Chinese medicine for treating diabetes mellitus and preparation method thereof
CN103550505A (en) * 2013-10-23 2014-02-05 王水争 Traditional Chinese medicine preparation for treating qi-yin deficiency type diabetes
CN103566177A (en) * 2012-07-26 2014-02-12 张夏思 Composition for treating early diabetes, preparation of composition and preparation method of preparation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1113146A (en) * 1994-03-08 1995-12-13 哈尔滨中药三厂 Prescription of preparation for curing diabetes
CN103566177A (en) * 2012-07-26 2014-02-12 张夏思 Composition for treating early diabetes, preparation of composition and preparation method of preparation
CN103055176A (en) * 2012-12-29 2013-04-24 王慎田 Traditional Chinese medicine for treating diabetes mellitus and preparation method thereof
CN103550505A (en) * 2013-10-23 2014-02-05 王水争 Traditional Chinese medicine preparation for treating qi-yin deficiency type diabetes

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