CN103007159B - Chinese medicinal preparation for correcting pancreas islet function - Google Patents
Chinese medicinal preparation for correcting pancreas islet function Download PDFInfo
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- CN103007159B CN103007159B CN201310015196.7A CN201310015196A CN103007159B CN 103007159 B CN103007159 B CN 103007159B CN 201310015196 A CN201310015196 A CN 201310015196A CN 103007159 B CN103007159 B CN 103007159B
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Abstract
The invention relates to a Chinese medicinal preparation for correcting pancreas islet function, and belongs to the technical field of Chinese medicine and Chinese medicaments. The Chinese medicinal preparation is prepared form prepared rehmannia, glossy privet fruit, chrysanthemum, cinnamon, honeysuckle, scurfpea fruit, gyp, cistanche, alpinia oxyphylla, spina date seed, rhizoma atractylodis, tortoise shell, kudzuvine root, cape jasmine, platycodon grandiflorum, amber, asparagus fern, calamus, schisandra chinensis, tribulusterrestris, lily, crude dragon bone, straight ladybell root, Chinese angelica root and white peony root. The preparation can be used for regulating vital energy of imbalanced internal organ, yin-yang and five elements of a diabetic patient, correcting control of cortical centre to the pancreas islet, so that the pancreas islet can work according to normal requirement of a human, and diabetes mellitus can be fundamentally cured. The Chinese medicinal preparation is strict in composition, excellent in drug selection and convenient to take, and does not have toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation of proofreading and correct islet function, belong to Chinese medicine technical field.
Background technology
Diabetes are one of global persistent ailments, also there is no at present the way that can cure completely, are the formidable enemies who threatens human life.Modern medicine thinks that diabetes are that a kind of chronic hyperglycemia is the metabolic disease of feature, is mainly that absolute deficiency or the relative deficiency due to insulin causes.The treatment way of this disease is at present: 1, promote cell tissue to sugared utilization, promote glucose to change glycogen into and be stored in muscle and liver, thereby make the blood glucose in body reduce (as insulin type); 2, optionally act on pancreaticβ-cell, promote the secretion of insulin.The insulin action of secretion, in liver, suppresses the decomposition of glycogen, can also promote the oxidation of intramuscular glucose simultaneously, thereby makes blood glucose in body reduce (as sulfonamides); 3, by increase, organize the zymolysis of anaerobic sugar, promote the picked-up of tissue to glucose, the glucose utilization in body is increased, thereby make the blood glucose in body reduce (as biguanides).
Existing Therapeutic Method is all that artificial sugar storage or decomposition unnecessary in body is oxidized, make blood glucose in body temporarily reach normal index scope, and pathological changes body constitution does not change, normal function carbohydrate metabolism does not recover, and just cannot fundamentally solve in human body insulin definitely or the problem of relative deficiency yet.Along with the prolongation of medical history, the infringement of human organ constantly increases the weight of, its complication arise at the historic moment (as: retina, the heart, brain, nephropathy, the pathological changes of nervous system and cardiac muscular tissue, vasculitis, ulcer of the lower limb and gangrene etc.).Modern medicine can only change the amount of diabetics, and can not change the matter of diabetics.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation of proofreading and correct islet function, adjust the gas of the unbalanced internal organs yin-yang and five elements of diabetics, proofread and correct the regulation and control of mesencephalic centre to islets of langerhans, make islets of langerhans by people's normal demand work, fundamentally cure diabetes.
The Chinese medicine preparation of correction islet function of the present invention, raw material of Chinese medicine by following parts by weight is made: Radix Rehmanniae Preparata 75-85 part, Fructus Ligustri Lucidi 75-85 part, Hemerocallis citrina Baroni 95-105 part, Cortex Cinnamomi 25-35 part, Flos Lonicerae 75-85 part, Fructus Psoraleae 55-65 part, Gypsum Fibrosum 75-85 part, Herba Cistanches 75-85 part, Fructus Alpiniae Oxyphyllae 55-65 part, Semen Ziziphi Spinosae 55-65 part, Rhizoma Atractylodis 25-35 part, Carapax et Plastrum Testudinis 55-65 part, Radix Puerariae 95-105 part, Fructus Gardeniae 55-65 part, Radix Platycodonis 25-35 part, succinum 25-35 part, Radix Asparagi 25-35 part, Rhizoma Acori Graminei 55-65 part, Fructus Schisandrae Chinensis 25-35 part, Fructus Atriplicis Sibiricae 95-105 part, Bulbus Lilii 55-65 part, Os Draconis 75-85 part, Radix Adenophorae (Radix Glehniae) 55-65 part, Radix Angelicae Sinensis 25-35 part, Semen Persicae 45-55 part and Radix Paeoniae Alba 25-35 part.
The Chinese medicine preparation of correction islet function of the present invention, preferably by the raw material of Chinese medicine of following parts by weight, made: 80 parts, Radix Rehmanniae Preparata, 80 parts of Fructus Ligustri Lucidi, 100 parts, Hemerocallis citrina Baroni, 30 parts of Cortex Cinnamomis, 80 parts of Flos Loniceraes, 60 parts of Fructus Psoraleaes, 80 parts, Gypsum Fibrosum, 80 parts of Herba Cistanches, 60 parts of Fructus Alpiniae Oxyphyllae, 60 parts of Semen Ziziphi Spinosaes, 30 parts of Rhizoma Atractylodis, 60 parts of Carapax et Plastrum Testudiniss, 100 parts of Radix Puerariaes, 60 parts of Fructus Gardeniaes, 30 parts of Radix Platycodoniss, 30 parts of succinums, 30 parts of Radix Asparagis, 60 parts of Rhizoma Acori Gramineis, 30 parts of Fructus Schisandrae Chinensis, 100 parts of Fructus Atriplicis Sibiricaees, 60 parts of Bulbus Liliies, 80 parts of Os Draconis, 60 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Radix Angelicae Sinensis, 30 parts of 50 parts, Semen Persicae and the Radix Paeoniae Albas.
The present invention can make acceptable various preparations on Chinese materia medica, preferably paste pill.
Preparation method: take raw material by above-mentioned parts by weight, it is 120 order fine powders that all medicines are pricked altogether, with boiled water by medicated powder general be paste pill, every ball weighs 1.2 grams, dry in the shade or cold drying, pack, sealing.
Therapeutic scheme: take paste pill of the present invention, each 10-15 ball, takes twice every day, clothes minute sooner or later, ante cibum, after meal all can, six fortnights are a course for the treatment of.
Because this preparation does not have blood sugar reducing function, so to the diabetics of insulin injection or oral antidiabetic drug, when taking preparation of the present invention, continue the antidiabetic drug before using, and the fasting glucose starting is kept a record, within later every 8 days, survey a fasting glucose.Recovery along with islet function, blood glucose constantly declines, patient is the low dose of antidiabetic drug (what can not subtract is too anxious) that reduces slowly, and general fasting glucose just can reduce in a small amount hypoglycemic medicine below 8mmol/L, and determines and subtract and do not subtract according to the situation of change of every 8 days fasting glucose.The inactive blood sugar lowering Western medicine until fasting glucose drops to normal value (experience is thought along with the reduction of blood glucose, uses the patient of insulin to be advisable to reduce 2-4Ge unit at every turn, uses the patient of oral antidiabetic drug, as 0.25g metformin, 25mg glibenclamide).Can reduce by half sheet is advisable at every turn.Diabetes are a kind of chronic diseases, and recovering islet function is a process slowly, and within several 8 days sometimes, blood glucose does not decline, and can not reduce Western medicine antidiabetic drug so with regard to several 8 days, and the time of some needs of patients more than 2 years could recover normal.
Fasting glucose is not more than 13mmol/L and did not use the diabetics of Western medicine hypoglycemic medicine, can directly use separately the Chinese medicine preparation of correction islet function of the present invention, and do not need to use Western medicine hypoglycemic medicine simultaneously, within every 8 days later, survey a fasting glucose and keep a record, to observe the situation of change of blood glucose.Until fasting glucose is while reaching normal value, then continues to take this preparation and consolidate a period of time drug withdrawal (experience is thought: do not use the diabetics of Western medicine hypoglycemic medicine, and recovered faster than the patient who used Western medicine antidiabetic drug).
Drug action mechanism of the present invention is as follows:
Radix Rehmanniae Preparata: the yin nourishing of enriching blood, life essence-filling, marrow-benefitting.
Fructus Ligustri Lucidi: liver and kidney tonifying; Clearind deficient heat, improving eyesight.
Hemerocallis citrina Baroni: have hemostasis, antiinflammatory, heat clearing away, dampness removing, help digestion, improving eyesight, the effect such as calm the nerves.
Cortex Cinnamomi: mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Warming the spleen and stomach, removing accumulated cold, promoting blood circulation.
Flos Lonicerae: can dispelling wind-heat, also kind removing summer-heat blood poison.
Fructus Psoraleae: reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha.
Gypsum Fibrosum: expelling pathogenic factors from muscles for clearing heat, relieving restlessness is quenched the thirst, heat-clearing and toxic substances removing, pathogenic fire purging.
Herba Cistanches: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.
Fructus Alpiniae Oxyphyllae: warming the spleen, warming the kidney, solid and gas, arresting seminal emission.
Semen Ziziphi Spinosae: sweet in the mouth, acid, property is flat.Can nourish conscience, calm the nerves, arresting sweating.
Rhizoma Atractylodis: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.
Carapax et Plastrum Testudinis: YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone
Radix Puerariae: induce sweat and bring down a fever, promote the production of body fluid, rash, yang invigorating antidiarrheal.
Fructus Gardeniae: pathogenic fire purging relieving restlessness; Clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body; Fructus Gardeniae Preparatus: cooling blood for hemostasis.
Radix Platycodonis: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.
Succinum: calmness, diuresis, invigorates blood circulation.
Radix Asparagi: nourshing Yin and drynsessmoistening prescription; Lung heat clearing is promoted the production of body fluid.
Rhizoma Acori Graminei: can dirtyly have one's ideas straightened out for warding off, a surname's gas is by expectorant, removing toxic substances, parasite killing.Control demented, infantile convulsion, coma due to phlegm syncope, anemofrigid-damp arthralgia, mouthful fulminant dysentery of keeping silent, external application carbuncle scabies.Have one's ideas straightened out, reduce phlegm, stomach invigorating.
Fructus Schisandrae Chinensis: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.
Fructus Atriplicis Sibiricae: suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.
Bulbus Lilii: replenishing YIN and removing heat, nourishing essence-blood.
Os Draconis: raw product subduing hyperactive YANG to ease mental disorders, for hyperactivity of YANG due to deficiency of YIN, irritated irritability, palpitation and insomnia, has a dizzy spell, the demented frightened disease of waiting.
Radix Adenophorae (Radix Glehniae): nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid, QI invigorating, reduces phlegm.
Radix Angelicae Sinensis: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.
Semen Persicae: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.
The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
Curative effect judgement:
Recovery from illness: fasting glucose maintains below 7mmol/L.
Effective: fasting glucose below 7mmol/L, once in a while higher than 7mmol/L, less stable.
Invalid: after taking medicine, fasting glucose does not reach below 7mmol/L.
Therapeutic outcome: treatment diabetics 100 examples, take paste pill of the present invention, a 10-15 ball, day takes twice, minute morning and evening clothes, ante cibum, after meal all can, take continuously ten courses for the treatment of, recovery from illness 84 examples, account for 84%, effective 11 examples, account for 11%, invalid 5 examples, account for 5%, total effective rate 95%.Shown in treatment, without any side effects to patient, three large routine tests and hepatic and renal function detect no abnormal.
Below enumerate several model cases:
1, Xi Wu village, patient north suburb town Liu, female, 62 years old, within 2006, sensation xerostomia was weak, removes hospital admission, looks into fasting glucose 13.6mmol/L, is diagnosed as diabetes.Injected since then insulin, the oral metformin of crossing, gliclazide, Guangzhou diabetes pill and glibenclamide, blood glucose is always high.Early coming up on March 29th, 2012, to look into fasting glucose be 10.5mmol/L in here.Give preparation of the present invention and take, each 10 balls, every twice-daily.Take 10 of Guangzhou diabetes pilles each, every day three times (every 10 balls are containing glibenclamide 2.5mg), 1 (25mg) is each for glibenclamide simultaneously, every day three times.
2, the peaceful village Zhu in north suburb town, man, 60 years old.The fasting glucose 9.8mmol/L that haves a medical check-up for 2002 takes antidiabetic drug all the time sometimes, sometimes refuses to obey.On April 4th, 2011 comes here to look into fasting glucose 10.1mmol/L, gives preparation of the present invention and takes, each 12 balls, every twice-daily.Take 2 of diformin tablets each, twice of every day simultaneously.
3, north suburb town Xi Wu village Zhang, female, 48 years old, look into the year before fasting glucose 9.8mmol/L, oneself do not take notice of, since in October, 2012, felt weak all over, frequent micturition, on October 8th, 2012 comes here with regard to indagation fasting glucose 10.8mmol/L, October 18 was looked into fasting glucose 10.7mmol/L, was diagnosed as diabetes.Give preparation of the present invention and take, each 15 balls, every twice-daily.Stop to eat sweet thing, other are lived as ordinary person.
Clinical drug of the present invention is used and shows to have the following advantages:
(1) the selected Chinese herbal medicine of the present invention all meets < < Pharmacopoeia of People's Republic of China > > regulation, adjust the gas of the unbalanced internal organs yin-yang and five elements of diabetics, proofread and correct the regulation and control of mesencephalic centre to islets of langerhans, make islets of langerhans by people's normal demand work, fundamentally cure diabetes.
(2) make vast diabetics break away from the harm that long-term taking chemical drugs brings to heart and brain kidney, avoided the generation of diabetic complication.
(3) prescription of the present invention rigorous, select YAOJING good, taking convenience, have no side effect.
The specific embodiment
Embodiment 1:
30 grams of 80 grams, Radix Rehmanniae Preparata, 80 grams of Fructus Ligustri Lucidi, 100 grams, Hemerocallis citrina Baroni, 30 grams of Cortex Cinnamomis, 80 grams of Flos Loniceraes, 60 grams of Fructus Psoraleaes, 80 grams, Gypsum Fibrosum, 80 grams of Herba Cistanches, 60 grams of Fructus Alpiniae Oxyphyllae, 60 grams of Semen Ziziphi Spinosaes, 30 grams of Rhizoma Atractylodis, 60 grams of Carapax et Plastrum Testudiniss, 100 grams of Radix Puerariaes, 60 grams of Fructus Gardeniaes, 30 grams of Radix Platycodoniss, 30 grams of succinums, 30 grams of Radix Asparagis, 60 grams of Rhizoma Acori Gramineis, 30 grams of Fructus Schisandrae Chinensis, 100 grams of Fructus Atriplicis Sibiricaees, 60 grams of Bulbus Liliies, 80 grams of Os Draconis, 60 grams of Radix Adenophorae (Radix Glehniae), 30 grams of Radix Angelicae Sinensis, 50 grams, Semen Persicae and the Radix Paeoniae Albas.
Preparation method: by said medicine concoct qualified, weigh and to assort, it is 120 order fine powders that all medicines are pricked altogether, with boiled water by medicated powder general be paste pill, every ball weighs 1.2 grams, dries in the shade or cold drying, pack, seals.Oral, a 10-15 ball, takes twice every day, and clothes minute sooner or later, all can after meal at ante cibum.
Embodiment 2:
30 grams of 75 grams, Radix Rehmanniae Preparata, 85 grams of Fructus Ligustri Lucidi, 105 grams, Hemerocallis citrina Baroni, 25 grams of Cortex Cinnamomis, 75 grams of Flos Loniceraes, 55 grams of Fructus Psoraleaes, 85 grams, Gypsum Fibrosum, 75 grams of Herba Cistanches, 65 grams of Fructus Alpiniae Oxyphyllae, 65 grams of Semen Ziziphi Spinosaes, 35 grams of Rhizoma Atractylodis, 55 grams of Carapax et Plastrum Testudiniss, 105 grams of Radix Puerariaes, 55 grams of Fructus Gardeniaes, 25 grams of Radix Platycodoniss, 35 grams of succinums, 35 grams of Radix Asparagis, 55 grams of Rhizoma Acori Gramineis, 25 grams of Fructus Schisandrae Chinensis, 105 grams of Fructus Atriplicis Sibiricaees, 65 grams of Bulbus Liliies, 85 grams of Os Draconis, 55 grams of Radix Adenophorae (Radix Glehniae), 25 grams of Radix Angelicae Sinensis, 55 grams, Semen Persicae and the Radix Paeoniae Albas.
Preparation method: by said medicine concoct qualified, weigh and to assort, it is 120 order fine powders that all medicines are pricked altogether, with boiled water by medicated powder general be paste pill, every ball weighs 1.2 grams, dries in the shade or cold drying, pack, seals.Oral, a 10-15 ball, takes twice every day, and clothes minute sooner or later, all can after meal at ante cibum.
Claims (2)
1. a Chinese medicine preparation of proofreading and correct islet function, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae Preparata 75-85 part, Fructus Ligustri Lucidi 75-85 part, Hemerocallis citrina Baroni 95-105 part, Cortex Cinnamomi 25-35 part, Flos Lonicerae 75-85 part, Fructus Psoraleae 55-65 part, Gypsum Fibrosum 75-85 part, Herba Cistanches 75-85 part, Fructus Alpiniae Oxyphyllae 55-65 part, Semen Ziziphi Spinosae 55-65 part, Rhizoma Atractylodis 25-35 part, Carapax et Plastrum Testudinis 55-65 part, Radix Puerariae 95-105 part, Fructus Gardeniae 55-65 part, Radix Platycodonis 25-35 part, succinum 25-35 part, Radix Asparagi 25-35 part, Rhizoma Acori Graminei 55-65 part, Fructus Schisandrae Chinensis 25-35 part, Fructus Atriplicis Sibiricae 95-105 part, Bulbus Lilii 55-65 part, Os Draconis 75-85 part, Radix Adenophorae (Radix Glehniae) 55-65 part, Radix Angelicae Sinensis 25-35 part, Semen Persicae 45-55 part and Radix Paeoniae Alba 25-35 part, preparation method: take raw material by above-mentioned parts by weight, it is 120 order fine powders that all medicines are pricked altogether, with boiled water by medicated powder general be paste pill, every ball weighs 1.2 grams, dry in the shade or cold drying, pack, sealing.
2. the Chinese medicine preparation of correction islet function according to claim 1, it is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 80 parts, Radix Rehmanniae Preparata, 80 parts of Fructus Ligustri Lucidi, 100 parts, Hemerocallis citrina Baroni, 30 parts of Cortex Cinnamomis, 80 parts of Flos Loniceraes, 60 parts of Fructus Psoraleaes, 80 parts, Gypsum Fibrosum, 80 parts of Herba Cistanches, 60 parts of Fructus Alpiniae Oxyphyllae, 60 parts of Semen Ziziphi Spinosaes, 30 parts of Rhizoma Atractylodis, 60 parts of Carapax et Plastrum Testudiniss, 100 parts of Radix Puerariaes, 60 parts of Fructus Gardeniaes, 30 parts of Radix Platycodoniss, 30 parts of succinums, 30 parts of Radix Asparagis, 60 parts of Rhizoma Acori Gramineis, 30 parts of Fructus Schisandrae Chinensis, 100 parts of Fructus Atriplicis Sibiricaees, 60 parts of Bulbus Liliies, 80 parts of Os Draconis, 60 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Radix Angelicae Sinensis, 30 parts of 50 parts, Semen Persicae and the Radix Paeoniae Albas.
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| CN106075246A (en) * | 2016-07-14 | 2016-11-09 | 李加义 | A kind of Chinese medicine composition preventing diabetes |
| CN105943992A (en) * | 2016-07-14 | 2016-09-21 | 李加义 | Traditional Chinese medicine composition for treating diabetes |
| CN105902930A (en) * | 2016-07-14 | 2016-08-31 | 李加义 | Herbal tea capable of preventing diabetes mellitus |
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| CN1123357C (en) * | 1999-06-25 | 2003-10-08 | 刘永香 | Powdered medicine for conditioning viscera and whole body |
| CN101716303B (en) * | 2009-11-18 | 2011-08-31 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating heart-deficiency timidity disease and preparation method thereof |
| CN101716000A (en) * | 2009-11-20 | 2010-06-02 | 深圳市唤然生物科技开发有限公司 | Traditional Chinese medice healthy liquid and preparation method thereof |
| CN102178301A (en) * | 2011-04-21 | 2011-09-14 | 深圳市唤然生物科技开发有限公司 | Blueberry health care beverage and preparation method thereof |
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