CN103007159A - Chinese medicinal preparation for correcting pancreas islet function - Google Patents
Chinese medicinal preparation for correcting pancreas islet function Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal preparation for correcting pancreas islet function, and belongs to the technical field of Chinese medicine and Chinese medicaments. The Chinese medicinal preparation is prepared form prepared rehmannia, glossy privet fruit, chrysanthemum, cinnamon, honeysuckle, scurfpea fruit, gyp, cistanche, alpinia oxyphylla, spina date seed, rhizoma atractylodis, tortoise shell, kudzuvine root, cape jasmine, platycodon grandiflorum, amber, asparagus fern, calamus, schisandra chinensis, tribulusterrestris, lily, crude dragon bone, straight ladybell root, Chinese angelica root and white peony root. The preparation can be used for regulating vital energy of imbalanced internal organ, yin-yang and five elements of a diabetic patient, correcting control of cortical centre to the pancreas islet, so that the pancreas islet can work according to normal requirement of a human, and diabetes mellitus can be fundamentally cured. The Chinese medicinal preparation is strict in composition, excellent in drug selection and convenient to take, and does not have toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation of proofreading and correct islet function, belong to the Chinese medicine technical field.
Background technology
Diabetes are one of global persistent ailments, also do not have at present the way that can cure fully, are the formidable enemies who threatens the human life.Modern medicine thinks that diabetes are that a kind of chronic hyperglycemia is the metabolic disease of feature, mainly is that absolute deficiency or the relative deficiency owing to insulin causes.Treatment way that at present should disease is: 1, promote cell tissue to the utilization of sugar, promote glucose to change glycogen into and be stored in muscle and the liver, thereby make the blood glucose in the body reduce (such as insulin type); 2, optionally act on pancreaticβ-cell, promote the secretion of insulin.The insulin action of secretion suppresses the decomposition of glycogen in liver, can also promote the oxidation of intramuscular glucose simultaneously, thereby makes blood glucose reduction (such as sulfonamides) in the body; 3, organize the zymolysis of anaerobic sugar by increase, promote tissue to the picked-up of glucose, the glucose utilization in the body is increased, thereby make the blood glucose in the body reduce (such as biguanides).
Existing Therapeutic Method all is artificial sugar unnecessary in the body is stored or decomposing oxidation, make the interior blood glucose of body temporarily reach the normal index scope, and pathological changes body constitution does not change, normal function carbohydrate metabolism does not recover, and just can't fundamentally solve the problem of the absolute or relative deficiency of insulin in the human body yet.Along with the prolongation of medical history, the infringement of human organ constantly increases the weight of, its complication arise at the historic moment (as: retina, the heart, brain, nephropathy, the pathological changes of nervous system and cardiac muscular tissue, vasculitis, ulcer of the lower limb and the gangrene etc.).Modern medicine can only change the amount of diabetics, and can not change the matter of diabetics.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine preparation of proofreading and correct islet function, adjust the gas of the unbalanced internal organs yin-yang and five elements of diabetics, proofread and correct mesencephalic centre to the regulation and control of islets of langerhans, make islets of langerhans by people's normal demand work, fundamentally cure diabetes.
The Chinese medicine preparation of correction islet function of the present invention is made by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae Preparata 75-85 part, Fructus Ligustri Lucidi 75-85 part, Hemerocallis citrina Baroni 95-105 part, Cortex Cinnamomi 25-35 part, Flos Lonicerae 75-85 part, Fructus Psoraleae 55-65 part, Gypsum Fibrosum 75-85 part, Herba Cistanches 75-85 part, Fructus Alpiniae Oxyphyllae 55-65 part, Semen Ziziphi Spinosae 55-65 part, Rhizoma Atractylodis 25-35 part, Carapax et Plastrum Testudinis 55-65 part, Radix Puerariae 95-105 part, Fructus Gardeniae 55-65 part, Radix Platycodonis 25-35 part, succinum 25-35 part, Radix Asparagi 25-35 part, Rhizoma Acori Graminei 55-65 part, Fructus Schisandrae Chinensis 25-35 part, Fructus Atriplicis Sibiricae 95-105 part, Bulbus Lilii 55-65 part, Os Draconis 75-85 part, Radix Adenophorae (Radix Glehniae) 55-65 part, Radix Angelicae Sinensis 25-35 part, Semen Persicae 45-55 part and Radix Paeoniae Alba 25-35 part.
The Chinese medicine preparation of correction islet function of the present invention is preferably made by the raw material of Chinese medicine of following parts by weight: 80 parts in Radix Rehmanniae Preparata, 80 parts of Fructus Ligustri Lucidi, 100 parts in Hemerocallis citrina Baroni, 30 parts of Cortex Cinnamomis, 80 parts of Flos Loniceraes, 60 parts of Fructus Psoraleaes, 80 parts in Gypsum Fibrosum, 80 parts of Herba Cistanches, 60 parts of Fructus Alpiniae Oxyphyllae, 60 parts of Semen Ziziphi Spinosaes, 30 parts of Rhizoma Atractylodis, 60 parts of Carapax et Plastrum Testudiniss, 100 parts of Radix Puerariaes, 60 parts of Fructus Gardeniaes, 30 parts of Radix Platycodoniss, 30 parts of succinums, 30 parts of Radix Asparagis, 60 parts of Rhizoma Acori Gramineis, 30 parts of Fructus Schisandrae Chinensis, 100 parts of Fructus Atriplicis Sibiricaees, 60 parts of Bulbus Liliies, 80 parts of Os Draconis, 60 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Radix Angelicae Sinensis, 30 parts of 50 parts in Semen Persicae and the Radix Paeoniae Albas.
The present invention can make acceptable various preparations on the Chinese materia medica, preferred paste pill.
Preparation method: take by weighing raw material by above-mentioned parts by weight, it is 120 order fine powders that all medicines are pricked altogether, with boiled water with medicated powder general be paste pill, every ball weigh 1.2 the gram, dry in the shade or cold drying, the pack, the sealing.
Therapeutic scheme: take paste pill of the present invention, each 10-15 ball takes twice every day, clothes minute sooner or later, ante cibum, after meal all can, six fortnights are a course for the treatment of.
Because this preparation does not have blood sugar reducing function, so to the diabetics of insulin injection or oral antidiabetic drug, when taking preparation of the present invention, continue to use former antidiabetic drug, and a fasting glucose of beginning keeps a record fasting glucose of survey in later per 8 days.Recovery along with islet function, blood glucose constantly descends, will be the slowly low dose of antidiabetic drug (what can not subtract is too anxious) that reduces of patient, general fasting glucose just can reduce hypoglycemic medicine in a small amount below 8mmol/L, and determines to subtract and do not subtract according to the situation of change of per 8 days empty stomach blood glucose.The inactive blood sugar lowering Western medicine until fasting glucose drops to normal value (experience is thought along with the reduction of blood glucose, uses the patient of insulin to be advisable to reduce by 2-4 unit at every turn, uses the patient of oral antidiabetic drug, such as 0.25g metformin, 25mg glibenclamide).Can reduce by half sheet is advisable at every turn.Diabetes are a kind of chronic diseases, and recovering islet function is a slowly process, and blood glucose did not descend in several 8 days sometimes, can not reduce the Western medicine antidiabetic drug with regard to several 8 days so, and the time of needs of patients more than 2 years that has could recover normal.
Fasting glucose is not more than 13mmol/L and did not use the diabetics of Western medicine hypoglycemic medicine, can directly use separately the Chinese medicine preparation of correction islet function of the present invention, and do not need to use simultaneously the Western medicine hypoglycemic medicine, per 8 days later on fasting glucose of survey also keep a record, to observe the situation of change of blood glucose.Until fasting glucose when reaching normal value, continues to take this preparation again and consolidates a period of time drug withdrawal (experience is thought: do not use the diabetics of Western medicine hypoglycemic medicine, and recovered faster than the patient who used the Western medicine antidiabetic drug).
Drug action mechanism of the present invention is as follows:
Radix Rehmanniae Preparata: the yin nourishing of enriching blood, life essence-filling, marrow-benefitting.
Fructus Ligustri Lucidi: liver and kidney tonifying; Clearind deficient heat makes eye bright.
Hemerocallis citrina Baroni: the effect such as hemostasis, antiinflammatory, heat clearing away, dampness removing are arranged, help digestion, make eye bright, calm the nerves.
Cortex Cinnamomi: it is supporing yang to mend fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Warming the spleen and stomach, removing accumulated cold, promoting blood circulation.
Flos Lonicerae: can dispelling wind-heat, also kind removing summer-heat blood poison.
Fructus Psoraleae: reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha.
Gypsum Fibrosum: expelling pathogenic factors from muscles for clearing heat, relieving restlessness quench the thirst, heat-clearing and toxic substances removing, pathogenic fire purging.
Herba Cistanches: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.
Fructus Alpiniae Oxyphyllae: warming the spleen, warming the kidney, solid and gas, arresting seminal emission.
Semen Ziziphi Spinosae: sweet in the mouth, acid, property is flat.Can nourish conscience, calm the nerves, arresting sweating.
Rhizoma Atractylodis: drying damp and strengthening spleen, expelling wind and cold makes eye bright.
Carapax et Plastrum Testudinis: YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone
Radix Puerariae: induce sweat and bring down a fever, promote the production of body fluid, rash, yang invigorating antidiarrheal.
Fructus Gardeniae: pathogenic fire purging relieving restlessness; Clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body; Fructus Gardeniae Preparatus: cooling blood for hemostasis.
Radix Platycodonis: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.
Succinum: calmness, diuresis is invigorated blood circulation.
Radix Asparagi: nourshing Yin and drynsessmoistening prescription; Lung heat clearing is promoted the production of body fluid.
Rhizoma Acori Graminei: can dirtyly have one's ideas straightened out for warding off, a surname's gas is by expectorant, detoxifcation, parasite killing.Control demented, infantile convulsion, coma due to phlegm syncope, anemofrigid-damp arthralgia, mouthful fulminant dysentery of keeping silent, external application carbuncle scabies.Have one's ideas straightened out, reduce phlegm, stomach invigorating.
Fructus Schisandrae Chinensis: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.
Fructus Atriplicis Sibiricae: suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.
Bulbus Lilii: replenishing YIN and removing heat, nourishing essence-blood.
Os Draconis: give birth to the product subduing hyperactive YANG to ease mental disorders, be used for hyperactivity of YANG due to deficiency of YIN, irritated irritability, palpitation and insomnia is had a dizzy spell, the demented frightened disease of waiting.
Radix Adenophorae (Radix Glehniae): nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid, QI invigorating is reduced phlegm.
Radix Angelicae Sinensis: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.
Semen Persicae: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.
The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
Curative effect is judged:
Recovery from illness: fasting glucose maintains below the 7mmol/L.
Effectively: fasting glucose is higher than 7mmol/L, less stable once in a while below 7mmol/L.
Invalid: the rear fasting glucose of taking medicine does not reach below the 7mmol/L.
Therapeutic outcome: treatment diabetics 100 examples, take paste pill of the present invention, a 10-15 ball, day takes twice, minute morning and evening clothes, ante cibum, after meal all can, take continuously ten courses for the treatment of, 84 examples of fully recovering account for 84%, effective 11 examples, account for 11%, invalid 5 examples account for 5%, total effective rate 95%.Shown in treatment, without any side effects to patient, three large routine tests and hepatic and renal function detect no abnormal.
Below enumerate several model cases:
1, Xi Wu village, patient north suburb town Liu, the woman, 62 years old, the sensation xerostomia was weak in 2006, removed hospital admission, looked into fasting glucose 13.6mmol/L, was diagnosed as diabetes.Injected since then insulin, the oral metformin of crossing, gliclazide, Guangzhou diabetes pill and glibenclamide, blood glucose are always high.Early coming up on March 29th, 2012, to look into fasting glucose be 10.5mmol/L in here.Give preparation of the present invention and take, each 10 balls, every twice-daily.It is each to take simultaneously 10 of Guangzhou diabetes pilles, and every day three times (per 10 balls contain glibenclamide 2.5mg), 1 (25mg) is each for glibenclamide, every day three times.
2, the peaceful village Zhu in north suburb town, man, 60 years old.The fasting glucose 9.8mmol/L that had a medical check-up in 2002 takes antidiabetic drug all the time sometimes, sometimes refuses to obey.On April 4th, 2011 came here to look into fasting glucose 10.1mmol/L, gave preparation of the present invention and took, each 12 balls, every twice-daily.It is each to take simultaneously 2 of diformin tablets, twice of every day.
3, Xi Wu village, north suburb town Zhang, the woman, 48 years old, look into the year before fasting glucose 9.8mmol/L, oneself do not take notice of, felt weak all over, frequent micturition since in October, 2012, on October 8th, 2012 came here with regard to indagation fasting glucose 10.8mmol/L, October 18 was looked into fasting glucose 10.7mmol/L, was diagnosed as diabetes.Give preparation of the present invention and take, each 15 balls, every twice-daily.Stop to eat sweet thing, other are lived such as ordinary person.
Clinical drug of the present invention uses and shows and have the following advantages:
(1) the selected Chinese herbal medicine of the present invention all meets Pharmacopoeia of the People's Republic of China regulation, adjust the gas of the unbalanced internal organs yin-yang and five elements of diabetics, proofread and correct mesencephalic centre to the regulation and control of islets of langerhans, make islets of langerhans by people's normal demand work, fundamentally cure diabetes.
(2) make vast diabetics break away from the long-term taking chemical drugs to the harm that the heart and brain kidney brings, avoided the generation of diabetic complication.
(3) prescription of the present invention rigorous, select YAOJING good, taking convenience, have no side effect.
The specific embodiment
Embodiment 1:
Radix Rehmanniae Preparata 80 gram, Fructus Ligustri Lucidi 80 grams, Hemerocallis citrina Baroni 100 grams, Cortex Cinnamomi 30 grams, Flos Lonicerae 80 grams, Fructus Psoraleae 60 grams, Gypsum Fibrosum 80 grams, Herba Cistanches 80 grams, Fructus Alpiniae Oxyphyllae 60 grams, Semen Ziziphi Spinosae 60 grams, Rhizoma Atractylodis 30 grams, Carapax et Plastrum Testudinis 60 grams, Radix Puerariae 100 grams, Fructus Gardeniae 60 grams, Radix Platycodonis 30 grams, succinum 30 grams, Radix Asparagi 30 grams, Rhizoma Acori Graminei 60 grams, Fructus Schisandrae Chinensis 30 grams, Fructus Atriplicis Sibiricae 100 grams, Bulbus Lilii 60 grams, Os Draconis 80 grams, Radix Adenophorae (Radix Glehniae) 60 grams, Radix Angelicae Sinensis 30 grams, Semen Persicae 50 grams and the Radix Paeoniae Alba 30 gram.
Preparation method: said medicine is concocted qualified, weighing assort, it is 120 order fine powders that all medicines are pricked altogether, with boiled water with medicated powder general be paste pill, every ball weighs 1.2 grams, dries in the shade or cold drying pack, sealing.Oral, a 10-15 ball takes twice every day, and clothes minute sooner or later, all can after meal at ante cibum.
Embodiment 2:
Radix Rehmanniae Preparata 75 gram, Fructus Ligustri Lucidi 85 grams, Hemerocallis citrina Baroni 105 grams, Cortex Cinnamomi 25 grams, Flos Lonicerae 75 grams, Fructus Psoraleae 55 grams, Gypsum Fibrosum 85 grams, Herba Cistanches 75 grams, Fructus Alpiniae Oxyphyllae 65 grams, Semen Ziziphi Spinosae 65 grams, Rhizoma Atractylodis 35 grams, Carapax et Plastrum Testudinis 55 grams, Radix Puerariae 105 grams, Fructus Gardeniae 55 grams, Radix Platycodonis 25 grams, succinum 35 grams, Radix Asparagi 35 grams, Rhizoma Acori Graminei 55 grams, Fructus Schisandrae Chinensis 25 grams, Fructus Atriplicis Sibiricae 105 grams, Bulbus Lilii 65 grams, Os Draconis 85 grams, Radix Adenophorae (Radix Glehniae) 55 grams, Radix Angelicae Sinensis 25 grams, Semen Persicae 55 grams and the Radix Paeoniae Alba 30 gram.
Preparation method: said medicine is concocted qualified, weighing assort, it is 120 order fine powders that all medicines are pricked altogether, with boiled water with medicated powder general be paste pill, every ball weighs 1.2 grams, dries in the shade or cold drying pack, sealing.Oral, a 10-15 ball takes twice every day, and clothes minute sooner or later, all can after meal at ante cibum.
Claims (3)
1. a Chinese medicine preparation of proofreading and correct islet function is characterized in that being made by the raw material of Chinese medicine of following parts by weight: Radix Rehmanniae Preparata 75-85 part, Fructus Ligustri Lucidi 75-85 part, Hemerocallis citrina Baroni 95-105 part, Cortex Cinnamomi 25-35 part, Flos Lonicerae 75-85 part, Fructus Psoraleae 55-65 part, Gypsum Fibrosum 75-85 part, Herba Cistanches 75-85 part, Fructus Alpiniae Oxyphyllae 55-65 part, Semen Ziziphi Spinosae 55-65 part, Rhizoma Atractylodis 25-35 part, Carapax et Plastrum Testudinis 55-65 part, Radix Puerariae 95-105 part, Fructus Gardeniae 55-65 part, Radix Platycodonis 25-35 part, succinum 25-35 part, Radix Asparagi 25-35 part, Rhizoma Acori Graminei 55-65 part, Fructus Schisandrae Chinensis 25-35 part, Fructus Atriplicis Sibiricae 95-105 part, Bulbus Lilii 55-65 part, Os Draconis 75-85 part, Radix Adenophorae (Radix Glehniae) 55-65 part, Radix Angelicae Sinensis 25-35 part, Semen Persicae 45-55 part and Radix Paeoniae Alba 25-35 part.
2. the Chinese medicine preparation of correction islet function according to claim 1 is characterized in that being made by the raw material of Chinese medicine of following parts by weight: 80 parts in Radix Rehmanniae Preparata, 80 parts of Fructus Ligustri Lucidi, 100 parts in Hemerocallis citrina Baroni, 30 parts of Cortex Cinnamomis, 80 parts of Flos Loniceraes, 60 parts of Fructus Psoraleaes, 80 parts in Gypsum Fibrosum, 80 parts of Herba Cistanches, 60 parts of Fructus Alpiniae Oxyphyllae, 60 parts of Semen Ziziphi Spinosaes, 30 parts of Rhizoma Atractylodis, 60 parts of Carapax et Plastrum Testudiniss, 100 parts of Radix Puerariaes, 60 parts of Fructus Gardeniaes, 30 parts of Radix Platycodoniss, 30 parts of succinums, 30 parts of Radix Asparagis, 60 parts of Rhizoma Acori Gramineis, 30 parts of Fructus Schisandrae Chinensis, 100 parts of Fructus Atriplicis Sibiricaees, 60 parts of Bulbus Liliies, 80 parts of Os Draconis, 60 parts of Radix Adenophorae (Radix Glehniae), 30 parts of Radix Angelicae Sinensis, 30 parts of 50 parts in Semen Persicae and the Radix Paeoniae Albas.
3. the Chinese medicine preparation of correction islet function according to claim 1 and 2 is characterized in that being paste pill.
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| CN105902930A (en) * | 2016-07-14 | 2016-08-31 | 李加义 | Herbal tea capable of preventing diabetes mellitus |
| CN105943992A (en) * | 2016-07-14 | 2016-09-21 | 李加义 | Traditional Chinese medicine composition for treating diabetes |
| CN106075246A (en) * | 2016-07-14 | 2016-11-09 | 李加义 | A kind of Chinese medicine composition preventing diabetes |
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| CN106075246A (en) * | 2016-07-14 | 2016-11-09 | 李加义 | A kind of Chinese medicine composition preventing diabetes |
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| CN103007159B (en) | 2014-04-02 |
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