CN101607031B - Medicated wine for curing and preventing diabetes mellitus, preparation method and application method thereof - Google Patents
Medicated wine for curing and preventing diabetes mellitus, preparation method and application method thereof Download PDFInfo
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- CN101607031B CN101607031B CN2009101574888A CN200910157488A CN101607031B CN 101607031 B CN101607031 B CN 101607031B CN 2009101574888 A CN2009101574888 A CN 2009101574888A CN 200910157488 A CN200910157488 A CN 200910157488A CN 101607031 B CN101607031 B CN 101607031B
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Abstract
The invention discloses a medicated wine for curing and preventing diabetes mellitus, a preparation method and an application method thereof. The medicated wine is prepared by the following materials by weight percent: 10-30 of eucommia bark, 10-30 of Japanese teasel, 10-30 of asparagus fern, 20-40 of foxnut, 40-60 of semen cuscutae, 40-60 of cornus officinalis sieb. et zucc, 10-30 of prepared rhizome of rehmannia, 5-20 of dried rhizome of rehmannia, 5-20 of dioscorea opposita thunb, 5-20 of lotus seed, 5-20 of morinda officinalis, 5-20 of polygonum multiflorum, 5-20 of pseudo-ginseng, 20-40 of milk veteh, 15-30 of salvia miltiorrhiza, 5-15 of ginseng, 5-15 of cordyceps sinensis and 5-15 of liquorice. The medicated wine has the advantages of remarkable curative effects, convenient drinking and no side effects.
Description
One, technical field
The present invention relates to the medicated wine and preparation method thereof and the using method of a kind of treatment and prevent diabetes, more particularly relating to a kind of is that raw material is treated and the medicated wine of prevent diabetes and preparation method thereof and using method with Chinese medicine.
Two, background technology
Diabetes are commonly encountered diseases, frequently-occurring disease, and annual morbidity is about 9,300,000, and diabetes have the tendency of extension and rejuvenation now, are second killers in the modern disease, and its harm to human body is only second to cancer, cause serious body and mind infringement and burden on society.Therefore, actively develop the study on prevention of diabetes, become an important topic.Disclose a kind of pharmaceutical composition for the treatment of diabetes and preparation method thereof in Chinese patent CN-02153464, but the dosage form that this patent is mentioned is more single, only be capsule, its content uniformity easily transfinites, and causes taking dose inaccurate; The stimulating gastrointestinal road; Moisture-sensitive, deliquescing, caking, even go mouldy, light, air, moisture etc. are all bigger to its influence; Be difficult for swallowing, be difficult for accept, patient that can not oral drugs can't use, and application surface is little.The effect of finding them in actual use is not special ideal.
Three, summary of the invention:
The object of the invention is to provide medicated wine of a kind of evident in efficacy, taking convenience and treatment that has no side effect and prevent diabetes and preparation method thereof and using method.
This and other purpose of the present invention will further embody and set forth by following detailed description and explanation.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to onset diabetes mechanism, achieve with reference to modern pharmacological research, from motherland's medicine treasure-house, filter out replenishing YIN and removing heat, blood stasis dispelling is promoted blood circulation, and the Chinese medicine that QI invigorating is reinforced the kidney is pressed the tcm theory prescription, effective component extracting makes the effect of its performance treatment and prevent diabetes, raise immunity, the quality of making the life better.
The medicated wine of treatment of the present invention and prevent diabetes is the medicated wine of being made by the raw material of following weight portion:
Cortex Eucommiae 10-30 Radix Dipsaci 10-30 Radix Asparagi 10-30
Semen euryales 20-40 Semen Cuscutae 40-60 Fructus Corni 40-60
Radix Rehmanniae Preparata 10-30 Radix Rehmanniae 5-20 RHIIZOMA DIOSCOREAE frOm Henan of China 5-20
Semen Nelumbinis 5-20 Radix Morindae Officinalis 5-20 Radix Polygoni Multiflori 5-20
Radix Notoginseng 5-20 Radix Astragali 20-40 Radix Salviae Miltiorrhizae 15-30
Radix Ginseng 5-15 Cordyceps 5-15 Radix Glycyrrhizae 5-15.
What can select is that the medicated wine of treatment of the present invention and prevent diabetes is the medicated wine of being made by the raw material of following weight portion:
Cortex Eucommiae 15-25 Radix Dipsaci 15-25 Radix Asparagi 15-25
Semen euryales 25-35 Semen Cuscutae 45-55 Fructus Corni 45-55
Radix Rehmanniae Preparata 15-25 Radix Rehmanniae 10-20 RHIIZOMA DIOSCOREAE frOm Henan of China 10-20
Semen Nelumbinis 10-20 Radix Morindae Officinalis 10-20 Radix Polygoni Multiflori 10-20
Radix Notoginseng 10-20 Radix Astragali 25-35 Radix Salviae Miltiorrhizae 20-30
Radix Ginseng 8-13 Cordyceps 8-13 Radix Glycyrrhizae 8-13.
Be preferably, the medicated wine of treatment of the present invention and prevent diabetes is the medicated wine of being made by the raw material of following weight portion:
The Cortex Eucommiae 20 Radix Dipsacis 20 Radix Asparagis 20
Semen euryales 30 Semen Cuscutae 50 Fructus Corni 50
Radix Rehmanniae Preparata 20 Radix Rehmanniae 15 RHIIZOMA DIOSCOREAE frOm Henan of China 15
Semen Nelumbinis 15 Radix Morindae Officinaliss 15 Radix Polygoni Multiflori 15
Radix Notoginseng 15 Radixs Astragali 30 Radix Salviae Miltiorrhizaes 25
Radix Ginseng 10 Cordycepss 10 Radix Glycyrrhizaes 10.
The preparation method of the medicated wine of treatment of the present invention and prevent diabetes is that the above-mentioned raw materials medical material is cleaned, and is processed into coarser powder and puts into cloth bag, steeps 6-15 days with the high spirit submergence, takes out cloth bag, again the cloth bag that takes out is put into yellow wine submergence bubble 10-20 days.
What can select is that the preparation method of the medicated wine of treatment of the present invention and prevent diabetes is that the above-mentioned raw materials medical material is cleaned, be processed into coarser powder and put into cloth bag, steeped 8-12 days with the high spirit submergence, take out cloth bag, again the cloth bag that takes out was put into yellow wine submergence bubble 13-16 days.
In the preparation method of the medicated wine of treatment of the present invention and prevent diabetes, the operating weight ratio of medical material and high spirit or yellow wine is 1: 10-20, be preferably, and the operating weight ratio of medical material and high spirit or yellow wine is 1: 12-18.
The using method of the medicated wine of treatment of the present invention and prevent diabetes is to drink the Chinese liquor 2 times of stating preparation every day, and each 20-25 gram drinks the yellow wine 2 times of stating preparation, each 30-50 gram.The sick recovery from illness of Third Mate's medicated wine, the few sexual life of period in a medicine, the water of not having tea is not jealous.
Below further specify the present invention by specific embodiment, but embodiment only be used for the explanation, can not limit the scope of the invention.
In the present invention, if not refer in particular to, all parts, amount, percentage ratio are unit of weight, and all raw materials all can be buied from market.
Four, the specific embodiment
Embodiment 1
Take by weighing raw material by following proportioning:
The Cortex Eucommiae 20 grams, Radix Dipsaci 20 grams, Radix Asparagi 20 grams, Semen euryales 30 grams, Semen Cuscutae 50 grams, Fructus Corni 50 grams, Radix Rehmanniae Preparata 20 grams, the Radix Rehmanniae 15 grams, bosom (Huaihe River) Rhizoma Dioscoreae 15 grams, Semen Nelumbinis 15 grams, Radix Morindae Officinalis 15 grams, Radix Polygoni Multiflori 15 grams, Radix Notoginseng 15 grams, the Radix Astragali 30 grams, Radix Salviae Miltiorrhizae 25 grams, Radix Ginseng 10 grams, Cordyceps 10 grams, Radix Glycyrrhizae 10 grams.
The above-mentioned raw materials medical material is cleaned, be processed into coarser powder and put into cloth bag, steeped 8-12 days, take out cloth bag, the cloth bag that takes out was put into 6 jin of yellow wine submergences bubbles 13-16 days again with 6 jin of high spirit submergences.
Using method is to drink the Chinese liquor 2 times of stating preparation every day, and each 20-25 gram drinks the yellow wine 2 times of stating preparation, each 30-50 gram.The sick recovery from illness of Third Mate's medicated wine, the few sexual life of period in a medicine, the water of not having tea is not jealous.
Embodiment 2
Take by weighing raw material by following proportioning:
The Cortex Eucommiae 10 grams, Radix Dipsaci 10 grams, Radix Asparagi 10 grams, Semen euryales 20 grams, Semen Cuscutae 40 grams, Fructus Corni 40 grams, Radix Rehmanniae Preparata 10 grams, the Radix Rehmanniae 5 grams, bosom (Huaihe River) Rhizoma Dioscoreae 5 grams, Semen Nelumbinis 5 grams, Radix Morindae Officinalis 5 grams, Radix Polygoni Multiflori 5 grams, Radix Notoginseng 5 grams, the Radix Astragali 20 grams, Radix Salviae Miltiorrhizae 15 grams, Radix Ginseng 5 grams, Cordyceps 5 grams, Radix Glycyrrhizae 5 grams.
The above-mentioned raw materials medical material is cleaned, be processed into coarser powder and put into cloth bag, steeped 10 days, take out cloth bag, again the cloth bag that takes out was put into 2400 gram yellow wine submergence bubbles 10 days with 2400 gram high spirit submergences.
Using method is to drink the Chinese liquor 2 times of stating preparation every day, and each 20-25 gram drinks the yellow wine 2 times of stating preparation, each 30-50 gram.The sick recovery from illness of Third Mate's medicated wine, the few sexual life of period in a medicine, the water of not having tea is not jealous.
Embodiment 3
Take by weighing raw material by following proportioning:
The Cortex Eucommiae 30 grams, Radix Dipsaci 30 grams, Radix Asparagi 30 grams, Semen euryales 40 grams, Semen Cuscutae 60 grams, Fructus Corni 60 grams, Radix Rehmanniae Preparata 30 grams, the Radix Rehmanniae 20 grams, bosom (Huaihe River) Rhizoma Dioscoreae 20 grams, Semen Nelumbinis 20 grams, Radix Morindae Officinalis 20 grams, Radix Polygoni Multiflori 20 grams, Radix Notoginseng 20 grams, the Radix Astragali 40 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Ginseng 15 grams, Cordyceps 15 grams, Radix Glycyrrhizae 15 grams.
The above-mentioned raw materials medical material is cleaned, be processed into coarser powder and put into cloth bag, steeped 10 days, take out cloth bag, again the cloth bag that takes out was put into 8000 gram yellow wine submergence bubbles 10 days with 8000 gram high spirit submergences.Using method is to drink the Chinese liquor 2 times of stating preparation every day, and each 20-25 gram drinks the yellow wine 2 times of stating preparation, each 30-50 gram.The sick recovery from illness of Third Mate's medicated wine, the few sexual life of period in a medicine, the water of not having tea is not jealous.
Embodiment 4: animal experiment
The oral acute toxicity test of rat takes once to irritate the method for feeding to medicated wine, the result show this medicated wine to the per os acute LD 50 of rat greater than 20ml/kg (3040mg/kg).The rats by intraperitoneal injection acute toxicity testing is taked the once abdominal cavity injection method, and the result shows that this medicine is 11.669ml/kg (1773.688mg/kg) to rat through the abdominal cavity acute LD 50.Rat feeds for long-term mouthful, dosage is respectively six, 12, ten octuple of clinical dosage, six months long term toxicity test results show that obvious poisoning symptom does not all appear in each dosage group rat, the hematuria routine, and blood parameters and histopathological examination are all less than obviously unusual.Therefore, this medicine had not both had acute toxicity, took for a long time not present long term toxicity yet.
Drug research: the experimental study of animal model of the hyperglycemia of chemical reagent being brought out by this medicine, result show that this medical instrument B cell that watches for animals is not subjected to the destructive effect of alloxan.The obvious effect that alloxan diabetes rats is had blood sugar lowering.Simultaneously, can also obviously improve the blood stasis situation of clinical patient, have the function that the control diabetic complication takes place, develops.
Clinical observation: the Luoyang diabetes study is used for this medicine clinical, has treated 1000 many cases diabetes patients.Total effective rate 91%.Wherein can be divided into four kinds of situations: one, the light or medical history shorter one of the state of an illness, subjective symptoms is improved, and quite a few patient still can keep normal level of postprandial blood sugar after progressively withdrawing antidiabetic drug; Two, the heavier or medical history of the state of an illness can comparatively ideally be kept blood sugar level than the elder with this medicine; Three, to each stage diabetics, this medicine has played the effect that prevent diabetes complication (especially vascular complication) takes place; Four, to existing this medicine of diabetic complication patient (especially vascular complication) not only can end its development, deterioration but also multiple pathological changes being had the obvious treatment effect.
Embodiment 5: clinical:
The applicant carries out a series of experiments, and can confirm that medicated wine provided by the invention and preparation method are effectively controlled, good effect.
1, grandson's generation is grand male 49 years old, lives the very capable driver of the people of Jiutai City, Jilin Province, after suffering from diabetes and not feeling any better for many years, eaten several pairs after sick recovery from illness.
2, what wealth man 47 forever, the row worker of Jiutai City, Jilin Province man, diabetes are found in health check-up in 1998 and the state of an illness is very serious, know this side after, drunk that ten pairs of these medicated wine are sick fully recovers.
3, Wang Si owed the man 39 years old, lived the chief personnel of Jiutai City, Jilin Province cooperative bank, and to seek the doctor invalid in many places for many years to suffer from diabetes, heard to have drunk seven pairs of medicated wine behind this side and just fully recover.
4, the rich man of Liu Zhi is 37 years old, and the hotel cook of Jiutai City, Jilin Province suffers from diabetes, has eaten 3 pairs of this medicated wine recoveries from illness.
5, Zhu Hua woman is 40 years old, and diabetes are suffered from for many years by 6 groups of the army and the people street, Jiutai City, Jilin Province 13 committees, listens a people to introduce to have taken five pairs of medicine buttons just to recover normal.
6, Song Ning woman is 29 years old, lives Ka Lun town, Jiutai City, Jilin Province, and the trouble diabetes are removed hospital's hospitalization DeGrain, hear of take this medicine 4 pairs all right.
7, close beautiful women 32 years old, diabetes are suffered from by the man fort peace of Jiutai City, Jilin Province dragon village 6 societies, have taken five pairs of medicine healths continuously just as ordinary person.
8, Song state good fortune man is 72 years old, and Shao Zuojia special product institute working in Jilin suffers from severe diabetes mellitus, abandoning cure, know this medicine after, reporting the attitude of having a try, eaten behind ten pairs of medicines just normally, meet the people and just say that this medicine is very refreshing.
9, the room is color gorgeous women 60 years old, and triumph 19 groups of people in Jiutai City, Jilin Province suffered from diabetes more than 30 year, seek medical advice everywhere to take medicine also and do not take a turn for the better, after eat ten pairs of recoveries from illness of this medicated wine.
10, Wang Ping woman is 42 years old, and Jiutai City, Jilin Province is 5 groups of communities along the river, suffer from existing four plus siges of diabetes, have obeyed Third Mate's medicated wine and have been clearly better, and have obeyed five pairs of medicated wine diabetes and have not just had.
11, permitted Yao man 27 years old, diabetes are suffered from for 5 groups in the army and the people street, Jiutai City, Jilin Province, and it is all right to have taken Third Mate's medicine.
12, Zhou Lijuan woman is 50 years old, and ditch town diabetes are grazed cattle Jiutai City for many years by Jilin Province, and the state of an illness does not always heal repeatedly, take five pairs of this medicines after, diabetes are all right.
13, Zhu Dayi man is 46 years old, and the Jiu Tai of the Jilin Province workman of system shop suffers from diabetes and listens that to have eaten Third Mate's medicated wine behind this side all right.
14, the Zhang Haifeng man is 30 years old, and striving village people in Changchun, Jilin Province suffers from diabetes, and it is sick all right to have eaten the Third Mate.
15, Wang Lei man is 47 years old, the Jiaohe people of Jilin Province, and suffering from diabetes 2003 for many years, to introduce this medicated wine through others good, and it is just normal just to have taken the Third Mate.
Claims (7)
1. the medicated wine of treatment and prevent diabetes is characterized in that it is the medicated wine of being made by the raw material of following weight portion:
Its preparation method is: the above-mentioned raw materials medical material is cleaned, be processed into coarser powder and put into cloth bag, steeped 6-15 days with the high spirit submergence, take out cloth bag, again the cloth bag that takes out was put into yellow wine submergence bubble 10-20 days.
2. the medicated wine of treatment according to claim 1 and prevent diabetes is characterized in that it is the medicated wine of being made by the raw material of following weight portion:
3. the medicated wine of treatment according to claim 1 and prevent diabetes is characterized in that it is the medicated wine of being made by the raw material of following weight portion:
4. according to the preparation method of the medicated wine of described treatment of one of claim 1-3 and prevent diabetes, it is characterized in that described raw medicinal material is cleaned, be processed into coarser powder and put into cloth bag, steeped 6-15 days with the high spirit submergence, take out cloth bag, again the cloth bag that takes out was put into yellow wine submergence bubble 10-20 days.
5. according to the preparation method of the medicated wine of described treatment of one of claim 1-3 and prevent diabetes, it is characterized in that described raw medicinal material is cleaned, be processed into coarser powder and put into cloth bag, steeped 8-12 days with the high spirit submergence, take out cloth bag, again the cloth bag that takes out was put into yellow wine submergence bubble 13-16 days.
6. according to the preparation method of the medicated wine of claim 4 or 5 described treatments and prevent diabetes, it is characterized in that the operating weight ratio of raw medicinal material and high spirit or yellow wine is 1: 10-20.
7. the preparation method of the medicated wine of treatment according to claim 6 and prevent diabetes is characterized in that the operating weight ratio of raw medicinal material and high spirit or yellow wine is 1: 12-18.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009101574888A CN101607031B (en) | 2009-07-31 | 2009-07-31 | Medicated wine for curing and preventing diabetes mellitus, preparation method and application method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009101574888A CN101607031B (en) | 2009-07-31 | 2009-07-31 | Medicated wine for curing and preventing diabetes mellitus, preparation method and application method thereof |
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| CN101607031B true CN101607031B (en) | 2011-12-14 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2487616A (en) * | 2011-01-25 | 2012-08-01 | qi ling Wang | Plant-based drug for diabetes |
| CN103721186B (en) * | 2013-12-18 | 2016-03-30 | 温建国 | A kind of medicine yellow wine for the treatment of diabetes and climacteric syndrome and preparation method thereof |
| CN104721580A (en) * | 2015-03-03 | 2015-06-24 | 刘正菊 | Traditional Chinese medicine composition for treating diabetes |
| CN104958536A (en) * | 2015-07-29 | 2015-10-07 | 青岛蓝盛洋医药生物科技有限责任公司 | Chinese medicinal composition for treating diabetes and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1108132A (en) * | 1995-01-18 | 1995-09-13 | 江苏省中谊科技公司 | Health-care medicinal liquor and its prepn. method |
| CN1151877A (en) * | 1995-12-12 | 1997-06-18 | 黄吉文 | Medicated wine and its prepn |
| CN1698799A (en) * | 2005-06-06 | 2005-11-23 | 姚力 | Medicinal wine for treating diabetes |
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2009
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1108132A (en) * | 1995-01-18 | 1995-09-13 | 江苏省中谊科技公司 | Health-care medicinal liquor and its prepn. method |
| CN1151877A (en) * | 1995-12-12 | 1997-06-18 | 黄吉文 | Medicated wine and its prepn |
| CN1698799A (en) * | 2005-06-06 | 2005-11-23 | 姚力 | Medicinal wine for treating diabetes |
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