GB2487616A - Plant-based drug for diabetes - Google Patents

Plant-based drug for diabetes Download PDF

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Publication number
GB2487616A
GB2487616A GB1116852.3A GB201116852A GB2487616A GB 2487616 A GB2487616 A GB 2487616A GB 201116852 A GB201116852 A GB 201116852A GB 2487616 A GB2487616 A GB 2487616A
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copies
diabetes
parts
papaya
poria
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GB201116852D0 (en
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qi ling Wang
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Priority claimed from CN201110026266XA external-priority patent/CN102100828A/en
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Priority to GB1116852.3A priority Critical patent/GB2487616A/en
Publication of GB201116852D0 publication Critical patent/GB201116852D0/en
Publication of GB2487616A publication Critical patent/GB2487616A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A drug for diabetes, containing: 2-6 parts sweet potato leaf; 1-6 parts yam; 1-3 parts licorice; 1-6 parts pueraria; 2-4 parts rehmanniae; 3-6 parts poria; 2-6 parts papaya; 1-4 parts bitter gourd/bitter melon; 1-3 parts yeast; 1-5 parts salvia.

Description

A diabetes drug The invention relates to drugs, specifically a treatment for diabetes drugs.
In the existing technology, diabetes has been difficult to cure a disease, although there are many drugs used to treat diabetes, but are not very effective treatment.
From the Western point of view, diabetes is a result of absolute or relative insulin secretion caused by increased blood glucose metabolism disorders caused by systemic endocrine metabolic disease. From the Chinese perspective, Diabetes Diabetes is a disease, divided on the consumer, the consumer, the next elimination, is the five internal organs are true, yin and yang imbalance, organs, pancreatic disorders, a variety of trace element imbalance causes a chronic disease.
Diabetes, elevated blood sugar is not that scary, but the complications of the hazards. Conventional medicine can only play a hypoglycemic effect of sugar control, because of its role in a single, can not control the complications. Brutal figures show: the current 40 million diabetics in China, 80% of patients associated with complications, including half of the patients eventually died of complications of diabetes. Diabetic retinopathy is the leading cause of blindness; 1 / 3 of those with acute myocardial infarction and 1 / 4 stroke and diabetic vascular disease has a direct relationship; vast majority of lower limb necrosis of lower limb amputees with vascular disease related to diabetes. As profit-driven, drug advertising publicity most hypoglycemic effect of drugs, while ignoring the complications of harm to patients with diabetes blood glucose control into a simple sugar treatment errors, not only so that patients lose their health, but also to families back a heavy economic burden for a diabetic patient per year cost of the sugar glucose is necessary to stabilize 5,000 yuan. However, after years of taking hypoglycemic agents, diet, and blood glucose after a fight in patients with diabetes found that his body is getting worse, increasingly blurred vision, body pain, limb numbness, decreased immunity, colds easily, wound healing, fatty liver, gallstones, gastrointestinal disorders, sexual dysfunction and so on. Serious complication of diabetic foot, only amputation; eye diseases so that patients lose the light; ketoacidosis, myocardial infarction, patients with uremia and even take lives. How to avoid amputation, blindness and death such a tragedy happen? Simply out ol control diabetes sugar to treatment errors, while the sugar in the blood glucose control, effective prevention and control of complications.
The purpose of the present invention for the pathogenesis of diabetes and clinical features of TOM Basic Theory, provides a low cost effective in the treatment of diabetes drugs.
Provide a diabetes drug, is the use of the following medicines or their extracts were prepared by mixing crushed; each herbs calculated by the number of copies, according to which: sweet potato leaf extract 2-6 copies, yam 1-6 copies Licorice 1-3 copies, Pueraria 1-6 copies, Rehmanniae 2-4 copies, Poria 3-6 copies, papaya 2-6 copies, bitter gourd were 1-4, 1-3 copies of the yeast, Salvia 1-5 copies; again Add the following extracts of herbs, medicinal herbs with the foregoing extract by adding weight ratio: Anoectochilus extract 2-7%, 2-9% glossy ganoderma powder.
In the treatment of diabetes drugs, including: sweet potato leaf extract 4 copies 3 copies of yam, licorice 2 copies 3 copies of puerarin, Rehmanniae 3 copies, Poria 5 copies 4 copies of papaya, bitter gourd 2 copies, 2 copies of the yeast, Salvia 3 copies.
In the treatment of diabetes drugs, including: sweet potato leaf extract 3 copies 2 copies of yam, licorice 1, Pueraria 1, Rehmanniae 2 copies, Poria 3 copies 2 copies of papaya, bitter gourd 1, yeast 1, Salvia 2 copies.
in the above drugs: Sweet potato leaf extracts: the major insulin f3 can repair damaged cells, promote the insulin 13 cells to restore damaged and proliferation of pancreatic islet cells to recuperate and vigor; directly address the shortage of people with diabetes and the relative lack of insulin is absolutely fundamental issue. In addition, from the natural extract of sweet potato leaves in the body can be transformed into a large number of arachidonic acid, which can reduce the role of blood lipids. Configuration of zinc, magnesium can promote the dissolution of the body-dimensional protein inhibition of thrombin generation, the blood vessels to dilate, to the role of anti-thrombosis; This product can effectively overcome the insulin resistance, in which the plant-specific peptide and protein molecular state, the body more easily than the animal insulin absorption, the long-term use can prevent diabetes complications.
Yam: the longevity of the product is good, taste flat, sweet, non-toxic. Lung, spleen, kidney, stomach. There spleen, thick stomach, lungs, kidney effect. Indications spleen diarrhea, Jiu Li, consumptive cough, nocturnal emission vaginal discharge, frequent urination, thirst, uterine prolapse.
Licorice: with Spleen Qi, detoxification, expectorant cough, urgency and pain relief, to reconcile the efficacy of various drugs. For the weak stomach, fatigue fatigue, palpitations shortness of breath, cough, sputum, abdominal, limb twin acute pain, carbuncle swollen sore, ease of drug toxicity, make five workers and injured seven, all wasting, through Jiuqiao, Lee Lotus, Yijing Yang Qi, strong bones, hot and cold solutions.
Glycyrrhetinic acid-like effect of corticosterone with the DNA, can promote sodium and water retention, increased potassium row, indicating mineralocorticoid-like effect; licorice extract, glycyrrhizin can atrophy of thymus, adrenal weight gain, blood eosinophfl leukocyte and lymphocytes decreased, increased urinary free type 17 -hydroxy corticosterone.
Kudzu: Sun Jie Ji, Touzhen diarrhea, Chufan thirst. Governance typhoid fever, headache, hot items strong, Fanre diabetes, diarrhea, dysentery, measles can not figure Ban, hypertension, angina, deafness.
Ethanol Fueraria extract, daidzein and puerarin significantly against aconitine-induced arrhythmias and the role of barium chloride, chloroform, puerarin also significantly reduced, adrenaline-induced arrhythmias time, puerarin could significantly reduced myocardial infarct size, is considered to be a 1-adrenergic receptor blockers.
Rehmanniae: sweet, bitter, cold. Can YangYinShengJin, heat and cooling blood.
Can promote blood clotting, increase peripheral leukocyte; to cardiac, diuretic, or high blood pressure; to protect the liver, lowering blood glucose; have enhanced immune function, anti-radiation damage and adrenal cortical hormone-like effect. Wound fluid for heat, thirst, dry throat, or dry stool; Diabetes, dry mouth and drink; blood heat Wang Xing, vomiting blood, Nvxue, hematochezia, uterine bleeding; warm disease, dry mouth, tongue crimson.
Poria: of sweet light levels, into the heart, lung, spleen. Diuresis with Shenshi, spleen and stomach, Ning Anshen effect. Can cure dysuria, edema, puffiness, phlegm, Keni, vomiting inverse, Vomiting, diarrhea, nocturnal emission, splashing muddy, palpitation, forgetfulness embolism. Poria and benefit from the water is transported through the health Pifei function to achieve, and other direct benefits of water of different traditional Chinese medicine. Lingguizhugan soup, Sijunzitang, four Ling Poria soup and so is compatible with the common prescriptions.
Diuretic, the Fuling Medicinal 70% alcohol cold soak, be soaked with liquid when the alcohol evaporates, add distilled water diluted urine significantly increased after treatment.
Salvia: Bitter, slightly cold. The heart, liver. With blood to regulate menstruation, blood stasis and pain, carbuncle cooling consumption, pure heart Chufan, nourishing and sedative effect. Indications, irregular menstruation, dysmenorrhea, amenorrhea, Zheng Jia accumulation, abdominal irritation, pain, heat paralysis, sore throat, upset, sleepless; hepatosplenomegaly, angina pectoris.
Papaya ingredients: papaya base, papain, rennet papaya, tomatoes, hydrocarbons, vitamins B, C, E, sugar, protein, fat, carotene, hidden flavin, flavin butterfly Mei, hidden flavin ring amide and so on. Natured, slightly cold, sweet. It has a unique anti-tumor effect of papaya base of lymphatic leukemia cells with strong anti-cancer activity.
Bitter: bitter gourd bitter odor, non-toxic, cold, into the heart, liver, spleen, lung; bitter summer heat with the heat, nourishing Qi, kidney and spleen, nourish liver eyesight of the efficacy of the treatment of dysentery, sores, heat stroke, fever, prickly heat too much, conjunctivitis and other diseases have a certain effect. High vitamin C content of bitter gourd, with the prevention of scurvy, protect cell membranes, prevent atherosclerosis, improve stress ability to protect the heart and so on. The active ingredients in bitter gourd can inhibit carcinogenesis and the promotion of normal cell recovery of mutant cells with certain anti-cancer effect. Bitter gourd in the prime as the "killer fat" can reduce the intake of fats and polysaccharides. Heat cured Firelight, detoxification, eyesight, qi, refined, refreshing thirst quencher, treatment carbuncle.
important nutritional factor of yeast species: Valley off glutathione: an extremely valuable activity of small peptides, a "super antioxidant," said, can efficiently remove harmful free radicals, protecting cells, play a anti-aging, protect the liver, a variety of detoxification, prevention of exercise-induced anemia effect.
Product contains chromium yeast: natural organic chromium supplement.
Composed of glucose measurement factor (CTP), strengthening the role of insulin to help stabilize blood sugar, and prevent arteriosclerosis.
Formosanus: Sweet, cold, with heat and cooling blood, sugar, desiccant detoxification, balance of yin and yang, strengthening and restoring the yin and yang complement each other, fluid beauty, qi and blood, internal organs, life support functions of sickness. Into the kidney, heart, lung three classics, to comprehensively improve the human immune system, enhance the body resistance to disease.
Indications Hyperactivity cough, tuberculosis, hemoptysis, hematuria, children convulsion, tetanus, nephritis, edema, Fengshibitong, bruises, snake bites, bronchitis, cystitis, diabetes, hematuria, acute and chronic hepatitis, rheumatic arthritis, cancer and other difficult cases.
Glossy ganoderma powder: the pancreas can improve blood circulation, improve physiological function of the pancreas, lowers blood sugar and other effects. On spontaneous, night sweats, Shenpi fatigue, shortness of breath, palpitations, insomnia, dizziness, chest tightness, gas hold back, poor appetite, backache and other symptoms were significantly improved Tuiruan, significant effect on lowering blood lipids.
In the drug formulation, the sweet potato leaf extract, yam, licorice, kudzu root, Rehmanniae, Poria, Salvia, papaya, bitter gourd and other raw materials is a drug with the food source, and compatibility of the herbs, solve diabetes during treatment with Other drugs need to stabilize blood glucose sugar problems, and better treatment.
Implementation Example: The following Chinese herbal medicines used to extract and mixed by crushing, or prepared from, can be made into tablets or capsules; each herbs calculated by the number of copies, according to which: sweet potato leaf extracts were 2-6, 1-6 yam copies 1-3 copies of licorice, Pueraria 1-6 copies, Rehmanniae 2-4 copies, Poria 3-6 copies, papaya 2-6 copies, bitter gourd were 1-4, 1-3 copies of the yeast, Salvia 1-5 copies; then add the following extracts of herbs, medicinal herbs with the foregoing extract by adding weight ratio: Anoectochilus extract 2-7%, 2-9% glossy ganoderma powder.
In the treatment of diabetes drugs: sweet potato leaf extract 4 copies 3 copies of yam, licorice 2 copies 3 copies of puerarin, Rehmanniae 3 copies, Poria 5 copies 4 copies of papaya, bitter gourd 2 copies, 2 copies of the yeast, SM 3 copies.
In the treatment of diabetes drugs: sweet potato leaf extract 3 copies 2 copies of yam, licorice 1, Pueraria 1, Rehmanniae 2 copies, Poria 3 copies 2 copies of papaya, bitter gourd 1, yeast 1, SM 2 copies.
Directions: three times a day 5, before meals, through 56 clinical cases observed 96% of the total effective rate after taking the drug significantly improved symptoms.
The drug effect: through the "up", added directly to insulin, "down", to quickly lower the blood sugar levels; "control" effective control of postprandial hyperglycemia; "repair" to repair an additional p-cell; "pass" to clear the glucose metabolic pathways; "defense", prevention and control of diabetes complications.
Help stabilize blood sugar and prevent complications, 54 cases of clinical cases by reaction, after three months after the trial of the drug, blood sugar levels stable, reducing the use of hypoglycemic drugs, no new complications of diabetes; physical improvement, significant improvement in physical, the ability to increase resistance to disease; to improve the quality of sleep.

Claims (3)

  1. CLAIMS1. A diabetes drug, characterized in that, it was prepared by crushing and mixing the following herbs or their extracts, and each herbs calculated by the number of copies, according to which: sweet potato leaf extracts were 2-6, yams 1 -6 copies, licorice 1- 3 copies, Pueraria 1-6 copies, Rehmanniae 2-4 copies, Poria 3-6 copies 2-6 copies papaya, bitter gourd were 1-4, 1-3 copies of the yeast, SM 1 -5 copies; then add the following extracts of herbs, medicinal herbs with the foregoing extract by adding weight ratio: Anoectochilus extract 2-7%, 2-9% glossy ganoderma powder.
  2. 2. The diabetes drug as in claim 1, characterized in that, including: sweet potato leaf extract 4 copies 3 copies of yam, licorice 2 copies 3 copies of puerarin, Rehmanniae 3 copies, Poria 5 copies, 4 copies of papaya, 2 copies of bitter melon, yeast 2 copies 3 copies of Salvia.
  3. 3. The diabetes drug as in claim 1, characterized in that, including: sweet potato leaf extract 3 copies, 2 copies of yam, licorice 1, Pueraria 1, Rehmanniae 2 copies, Poria 3 copies 2 copies of papaya, bitter gourd 1, yeast 1, SM 2 copies.
GB1116852.3A 2011-01-25 2011-09-30 Plant-based drug for diabetes Withdrawn GB2487616A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1116852.3A GB2487616A (en) 2011-01-25 2011-09-30 Plant-based drug for diabetes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110026266XA CN102100828A (en) 2011-01-25 2011-01-25 Medicament for treating diabetes mellitus
GB1116852.3A GB2487616A (en) 2011-01-25 2011-09-30 Plant-based drug for diabetes

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GB201116852D0 GB201116852D0 (en) 2011-11-09
GB2487616A true GB2487616A (en) 2012-08-01

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020011015A (en) * 2000-07-31 2002-02-07 김철주 Compositions for the treatment of diabetes
CN101530538A (en) * 2008-03-13 2009-09-16 北京天科仁祥医药科技有限公司 Oral preparation for treating diabetes mellitus
CN101607031A (en) * 2009-07-31 2009-12-23 董哲 Medicated wine of a kind of treatment and prevent diabetes and preparation method thereof and using method
CN101607073A (en) * 2008-06-20 2009-12-23 刘广伦 A kind of traditional biological technology is cultivated the method for Chinese medicine health care product Herba Swertiae davidi and healthy liquid thereof
CN101972415A (en) * 2010-06-07 2011-02-16 中山市新运来医药科技开发有限公司 Traditional Chinese medicine-decocted soup or granule preparation for recuperating and treating diabetes
CN102100828A (en) * 2011-01-25 2011-06-22 王启凌 Medicament for treating diabetes mellitus

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020011015A (en) * 2000-07-31 2002-02-07 김철주 Compositions for the treatment of diabetes
CN101530538A (en) * 2008-03-13 2009-09-16 北京天科仁祥医药科技有限公司 Oral preparation for treating diabetes mellitus
CN101607073A (en) * 2008-06-20 2009-12-23 刘广伦 A kind of traditional biological technology is cultivated the method for Chinese medicine health care product Herba Swertiae davidi and healthy liquid thereof
CN101607031A (en) * 2009-07-31 2009-12-23 董哲 Medicated wine of a kind of treatment and prevent diabetes and preparation method thereof and using method
CN101972415A (en) * 2010-06-07 2011-02-16 中山市新运来医药科技开发有限公司 Traditional Chinese medicine-decocted soup or granule preparation for recuperating and treating diabetes
CN102100828A (en) * 2011-01-25 2011-06-22 王启凌 Medicament for treating diabetes mellitus

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