CN102100828A - Medicament for treating diabetes mellitus - Google Patents

Medicament for treating diabetes mellitus Download PDF

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Publication number
CN102100828A
CN102100828A CN201110026266XA CN201110026266A CN102100828A CN 102100828 A CN102100828 A CN 102100828A CN 201110026266X A CN201110026266X A CN 201110026266XA CN 201110026266 A CN201110026266 A CN 201110026266A CN 102100828 A CN102100828 A CN 102100828A
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parts
radix
extract
root
medicine
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CN201110026266XA
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王启凌
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Abstract

The invention discloses a medicament for treating diabetes mellitus, which is prepared by crushing and mixing the following Chinese medicinal materials in part by weight: 2 to 6 parts of sweet potato leaf extract, 1 to 6 parts of cinnamomvine, 1 to 3 parts of liquoric root, 1 to 6 parts of kudzuvine root, 2 to 4 parts of raw rehmannia root, 3 to 6 parts of Indian buead, 2 to 6 parts of Chinese flowering quince, 1 to 4 parts of balsam pear, 1 to 3 parts of yeast and 1 to 5 parts of root of red-rooted salvia or extracts thereof in percentage by weight: 2 to 7 percent of golden hair grass extract and 2 to 9 percent of sporoderm-broken lucid ganoderma spore powder. In a formula of the medicament, raw materials including the sweet potato leaf extract, cinnamomvine, liquoric root, kudzuvine root, raw rehmannia root, Indian buead, Chinese flowering quince, balsam pear and the like are homologous in medicine and food; and by the compatibility of the medicinal materials, the problem of patients who suffer from the diabetes mellitus need to reduce blood sugar and stabilize blood sugar during the adoption of other medicaments in the process of treatment is solved, and the treatment effect is better.

Description

A kind of medicine for the treatment of diabetes
Technical field
The present invention relates to medicine, be specifically related to a kind of medicine for the treatment of diabetes.
Background technology
In the prior art, diabetes are a kind of diseases of very difficult healing always, though there are a lot of medicines to be used for treating diabetes, all do not have effectively therapeutic effect.
From doctor trained in Western medicine, diabetes are a kind of metabolism endocrine systemic diseases that cause blood glucose to increase to cause organism metabolic disorder because of the absolute or relative hyposecretion of insulin.From traditional Chinese medical science angle analysis, diabetes spp is in diabetes, disappear on the branch, in disappear, diabetes due to kidney-deficiency, be that the five internal organs are all empty, imbalance of YIN and YANG, the vital organs of the human body, disturbances of pancreas, a kind of chronic disease that multiple reason that trace element is unbalance causes.
The fearful part of diabetes does not also lie in the rising of blood glucose, but the harm of complication.Routine administration can only play the effect of blood sugar lowering, control sugar, because its effect is single, and the generation of uncontrollable complication.Cruel numeral shows: 80% patient is with complication in China's 4,000 ten thousand diabeticss at present, and wherein the patient of half finally dies from diabetic complication.Diabetic retinopathy is the first cause of blinding; 1/3 acute myocardial infarction person and 1/4 apoplexy patient and diabetic angiopathy have direct relation; Most lower limbs necrosis amputees become relevant with vasculopathy of the lower extremity in diabetes.Because interests are ordered about, mostly propagate the blood sugar reducing function of medicine in the advertisement of drugs, and ignored the harm of complication, make diabetics be absorbed in the treatment mistaken ideas of simple blood sugar lowering control sugar, this not only makes the patient lose one's health, also allow family also back heavy financial burden, diabetics is used for the expense of the steady sugar of blood sugar lowering every year will more than 5000 yuan.Yet through take antidiabetic drug for many years, keep on a diet, with the struggle of blood glucose after, diabetics is found, own health worse and worse, vision is more and more fuzzyyer, systemic pain, extremity are numb, immunity degradation, very easily flu, wound are difficult for healing, fatty liver, cholelithiasis, gastrointestinal dysfunction, sexual dysfunction etc.The severe complications diabetic foot can only amputation; The eye pathological changes allows the patient lose light; Ketoacidosis, myocardial infarction, uremia even can seize patient's life.How to avoid amputation, blind, dead such tragedy to take place? the diabetes patient must walk out the treatment mistaken ideas of simple control sugar, in blood sugar lowering control sugar, effectively prevents and control complication.
Summary of the invention
Purpose of the present invention, at the pathogeny and the clinical manifestation of diabetes, Basic Theories of Chinese Medicine provides a kind of cost low for instructing, and can effectively treat the medicine of diabetes.
A kind of medicine for the treatment of diabetes is provided, and is to adopt following traditional Chinese medicines material or its extract to be mixed with through pulverizing to obtain; Every kind of medical material is pressed umber and is calculated, and presses wherein: Radix Pachyrhizi Erosi leaf extract 2-6 part, Rhizoma Dioscoreae 1-6 part, Radix Glycyrrhizae 1-3 part, Radix Puerariae 1-6 part, Radix Rehmanniae 2-4 part, Poria 3-6 part, Fructus Chaenomelis 2-6 part, Fructus Momordicae charantiae 1-4 part, yeast 1-3 part, Radix Salviae Miltiorrhizae 1-5 part; The extract that adds following medicinal materials again, extract adds by the weight ratio with aforementioned medical material: Herba Anoectochili roxburghii extract 2-7%, ganoderma lucidum wall-broken powder 2-9%.
In the medicine of above-mentioned treatment diabetes, wherein: 4 parts of Radix Pachyrhizi Erosi leaf extracts, 3 parts of Rhizoma Dioscoreaes, 2 parts in Radix Glycyrrhizae, 3 parts of Radix Puerariaes, 3 parts of Radix Rehmanniae, 5 parts in Poria, 4 parts of Fructus Chaenomeliss, 2 parts in Fructus Momordicae charantiae, 2 parts in yeast, 3 parts of Radix Salviae Miltiorrhizaes.
In the medicine of above-mentioned treatment diabetes, wherein: 3 parts of Radix Pachyrhizi Erosi leaf extracts, 2 parts of Rhizoma Dioscoreaes, 1 part in Radix Glycyrrhizae, 1 part of Radix Puerariae, 2 parts of Radix Rehmanniae, 3 parts in Poria, 2 parts of Fructus Chaenomeliss, 1 part in Fructus Momordicae charantiae, 1 part in yeast, 2 parts of Radix Salviae Miltiorrhizaes.
In said medicine:
Radix Pachyrhizi Erosi leaf extract: mainly can repair impaired insulin β cell, promote impaired insulin β cellular-restoring and propagation, allow islet cells rehabilitate, invigorate, directly solve the root problem of absolute deficiency of diabetes patient's insulin and relative deficiency.In addition, that extracts from pure natural Radix Pachyrhizi Erosi leaf can be converted into tetraenoic acid in a large number in vivo, thereby reaches the effect of blood fat reducing.Configuration trace element zinc, magnesium can promote the generation of human body fibrillarin dissolving Trombin inhibiting, distend the blood vessels, and reach antithrombotic effect;
This product can also effectively overcome insulin resistant, and wherein distinctive plant molecular attitude polypeptide protein is absorbed by human body than animal insulin is easier, therefore takes many complication of all right prevent diabetes for a long time.
Rhizoma Dioscoreae: be the product of good life lengthening, it is flat, sweet, nontoxic to distinguish the flavor of.Go into lung, spleen, kidney, stomach.The effect that spleen invigorating, thick the intestines and stomach, tonifying the lung, kidney tonifying are arranged.Cure mainly diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, the seminal emission leukorrhagia, frequent micturition, quench one's thirst, uterine prolapse.
Radix Glycyrrhizae: effect with invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, mend five kinds of strain and seven kinds of impairment, all deficient, logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle is separated cold and hot.
Enoxolone has the effect of desoxycortone sample, can promote sodium, water retention, and row's potassium increases, and shows the effect of mineralocorticoid sample; Radix Glycyrrhizae extractum, glycyrrhizin can make that atrophy of thymus gland, adrenal gland's weight increase, eosinophil leucocyte and lymphopenia, the release 17-hydroxycorticosterone in increase urine middle reaches in the blood.
Radix Puerariae: the yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is quenched the thirst.Cure the wound that cold, warm headache, dysphoria with smothery sensation are quenched one's thirst, had loose bowels, dysentery, skin eruption are saturating, hypertension, angina pectoris, deafness.
The arrhythmia effect that Radix Puerariae alcohol extractum, daidzein and puerarin all have tangible antagonism aconitine and barium chloride to bring out, puerarin can also obviously shorten the arrhythmia time that chlorine is walked back and forth, epinephrine brings out, puerarin can obviously dwindle myocardial infarct size, is considered to a kind of receptor, blocker.
Radix Rehmanniae: sweet in the mouth, hardship, cold in nature.The energy YIN nourishing and the production of body fluid promoting, clearing away heat and cooling blood.Can promote blood coagulation, rising peripheral leukocytes; Energy heart tonifying, diuresis, rising blood pressure; The energy the liver protecting, blood sugar lowering; Raise immunity, Antiradiation injury and the effect of adrenocortical hormone sample are arranged.Be used for consumption of body fluid by heat, thirsty and dry pharynx, constipation with dry stool; Diabetes, the xerostomia polydipsia; Bleeding due to blood-heat, haematemesis, epistaxis, have blood in stool, metrorrhagia.
Poria: the property slightly sweet flavor is flat, goes into the heart, lung, spleen three warps.Has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can control dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, have loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, disease such as forgetful.The diuretic of Poria reaches by strong activating the spleen pulmonary function, and is different with the Chinese medicine of other direct diuretic.Linggui zhugan decoction, decoction of four noble drugs, four Siberian cocklebur soup etc. all are prescriptions commonly used that the Poria compatibility is arranged.
Diuresis, with the Poria crude drug with 70% ethanol merceration, will soak during use the vaporized alcohol of liquid, the adding distil water dilution, the urine amount is significantly increased after the medication.
Radix Salviae Miltiorrhizae: bitter in the mouth is slightly cold.GUIXIN, Liver Channel.Promoting blood flow to regulate menstruation is arranged, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, the effect of nourishing blood to tranquillize the mind.Cure mainly, menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swell and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.
The composition of Fructus Chaenomelis: carpaine, papain, chymopapain, lycopene, vitamin B, C, E, sugar, protein, fat, carotene, cryptoxanthine, violaxanthin, cryptoxanthine ring amide etc.
Fructus Chaenomelis property is put down, is slightly cold, sweet in the mouth.Its exclusive Fructus Chaenomelis alkali has antitumor efficacy, and the lymphoid leukemia cell is had strong active anticancer.
Fructus Momordicae charantiae: Fructus Momordicae charantiae abnormal smells from the patient hardship, nontoxic, cold in nature, go into the heart, liver, spleen, lung meridian; Fructus Momordicae charantiae has the effect of clearing away heat and removing summer, nourishing blood and invigorating qi, kidney and spleen invigorating, nourishing liver for improving eyesight, and, heatstroke heating swollen to treatment dysentery, skin ulcer, miliaria are too much, diseases such as conjunctivitis have certain effect.The Vitamin C content of Fructus Momordicae charantiae is very high, has the prevention vitamin C deficiency, protects cell membrane, prevents atherosclerosis, improves the physical stress ability, effect such as protection heart.Effective ingredient in the Fructus Momordicae charantiae can suppress Normocellular canceration and promote the recovery of mutant cell, has certain antitumaous effect.Charantin in the Fructus Momordicae charantiae is described as " fatty killer " can make picked-up fat and polysaccharide reduce.Heat clearing away dispel heart-fire, detoxify, make eye bright, the QI invigorating benefit is smart, quench the thirst and relieve summer heat, control carbuncle.
The important trophic factors of yeast kind:
Paddy takes off sweet peptide: a kind of extremely precious active small peptide, the title of " super polyphenoils " is arranged, and can efficiently remove harmful free radical, the protection cell plays defying age, the liver protecting, multiple detoxifcation, effects such as prevention sports anemia.
Yeast chromium: can replenish natural organic chromium, can form the glucose metering factor (CTP), potentiating insulin action helps to stablize blood glucose, and the prevention of arterial sclerosis.
Herba Anoectochili roxburghii: sweet in the mouth, cool in nature, have clearing away heat and cooling blood, blood sugar lowering, removing dampness and detoxicating, Yin Yang balancing, strengthening the body resistance, yin yang complementarity, the skin care of promoting the production of body fluid, QI and blood regulating, the five internal organs, support the function that the longevity prolongs life.Go into kidney, the heart, lung three warps, can improve body immunity comprehensively, strengthen the resistance of human body disease.Cure mainly difficult and complicated illness such as cough due to lung-heat, hemoptysis of pulmonary tuberculosis, hematuria, infantile convulsion, tetanus, oedema due to nephritis, rheumatic arthralgia, traumatic injury, venom, bronchitis, cystitis, diabetes, hematuria, acute, chronic hepatitis, rheumatic arthritis tumor.
Ganoderma lucidum wall-broken powder: have the pancreas of improvement blood circulation, improve the pancreas physiological function, effects such as blood sugar lowering.To spontaneous perspiration, night sweat, spiritlessness and weakness, shortness of breath and palpitation, have a sleepless night, have a dizzy spell, symptom such as suffocated breathing uncomfortable in chest, off feed, waist soreness all has clear improvement, and blood fat reducing is had obvious effect.
In the said medicine prescription, raw materials such as Radix Pachyrhizi Erosi leaf extract, Rhizoma Dioscoreae, Radix Glycyrrhizae, Radix Puerariae, Radix Rehmanniae, Poria, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Fructus Momordicae charantiae are that the medicine source is with food, behind the above-mentioned medical material compatibility, can solve the diabetes patient and in therapeutic process, adopt other medicines to need the steady sugared problem of blood sugar lowering, and therapeutic effect is better.
The specific embodiment
Embodiment one: adopt the following traditional Chinese medicines material to obtain through pulverizing or extracting and be mixed with, can make tablet or capsule; Every kind of medical material is pressed umber and is calculated, and presses wherein: Radix Pachyrhizi Erosi leaf extract 2-6 part, Rhizoma Dioscoreae 1-6 part, Radix Glycyrrhizae 1-3 part, Radix Puerariae 1-6 part, Radix Rehmanniae 2-4 part, Poria 3-6 part, Fructus Chaenomelis 2-6 part, Fructus Momordicae charantiae 1-4 part, yeast 1-3 part, Radix Salviae Miltiorrhizae 1-5 part; The extract that adds following medicinal materials again, extract adds by the weight ratio with aforementioned medical material: Herba Anoectochili roxburghii extract 2-7%, ganoderma lucidum wall-broken powder 2-9%.
In the medicine of above-mentioned treatment diabetes: 4 parts of Radix Pachyrhizi Erosi leaf extracts, 3 parts of Rhizoma Dioscoreaes, 2 parts in Radix Glycyrrhizae, 3 parts of Radix Puerariaes, 3 parts of Radix Rehmanniae, 5 parts in Poria, 4 parts of Fructus Chaenomeliss, 2 parts in Fructus Momordicae charantiae, 2 parts in yeast, 3 parts of Radix Salviae Miltiorrhizaes.
In the medicine of above-mentioned treatment diabetes: 3 parts of Radix Pachyrhizi Erosi leaf extracts, 2 parts of Rhizoma Dioscoreaes, 1 part in Radix Glycyrrhizae, 1 part of Radix Puerariae, 2 parts of Radix Rehmanniae, 3 parts in Poria, 2 parts of Fructus Chaenomeliss, 1 part in Fructus Momordicae charantiae, 1 part in yeast, 2 parts of Radix Salviae Miltiorrhizaes.
Instructions about how to take medicine: every day three times, each 5, taking medicine before meal usefulness is observed by 56 routine clinical cases and to be found that total effective rate reaches 96%, take this medicine after, symptom all has clear improvement.
This medicine effect: by " benefit ", direct supplementation with insulin, " falling ", blood sugar lowering content rapidly; " control " effectively controlled post-prandial glycemia and raise; " repair ", repair and add beta Cell of islet; " lead to " metabolic pathway of mediation glucose; " prevent " prevention and control of diabetes complication.
Help stablize blood glucose, and prevent complication, by 54 routine clinical cases reactions, through behind three months trial edition medicines, blood sugar level is stable, and used hypoglycemic medicine decrement does not have new diabetic complication appearance; Body constitution is improved, and muscle power is clearly better, and the ability of resist the disease strengthens; Sleep quality improves.

Claims (3)

1. a medicine for the treatment of diabetes is characterized in that, is to adopt following traditional Chinese medicines material or its extract to be mixed with through pulverizing to obtain; Every kind of medical material is pressed umber and is calculated, and presses wherein: Radix Pachyrhizi Erosi leaf extract 2-6 part, Rhizoma Dioscoreae 1-6 part, Radix Glycyrrhizae 1-3 part, Radix Puerariae 1-6 part, Radix Rehmanniae 2-4 part, Poria 3-6 part, Fructus Chaenomelis 2-6 part, Fructus Momordicae charantiae 1-4 part, yeast 1-3 part, Radix Salviae Miltiorrhizae 1-5 part; The extract that adds following medicinal materials again, extract adds by the weight ratio with aforementioned medical material: Herba Anoectochili roxburghii extract 2-7%, ganoderma lucidum wall-broken powder 2-9%.
2. according to the medicine of the described treatment diabetes of claim 1, it is characterized in that, wherein: 4 parts of Radix Pachyrhizi Erosi leaf extracts, 3 parts of Rhizoma Dioscoreaes, 2 parts in Radix Glycyrrhizae, 3 parts of Radix Puerariaes, 3 parts of Radix Rehmanniae, 5 parts in Poria, 4 parts of Fructus Chaenomeliss, 2 parts in Fructus Momordicae charantiae, 2 parts in yeast, 3 parts of Radix Salviae Miltiorrhizaes.
3. according to the medicine of the described treatment diabetes of claim 1, it is characterized in that, wherein: 3 parts of Radix Pachyrhizi Erosi leaf extracts, 2 parts of Rhizoma Dioscoreaes, 1 part in Radix Glycyrrhizae, 1 part of Radix Puerariae, 2 parts of Radix Rehmanniae, 3 parts in Poria, 2 parts of Fructus Chaenomeliss, 1 part in Fructus Momordicae charantiae, 1 part in yeast, 2 parts of Radix Salviae Miltiorrhizaes.
CN201110026266XA 2011-01-25 2011-01-25 Medicament for treating diabetes mellitus Pending CN102100828A (en)

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CN201110026266XA CN102100828A (en) 2011-01-25 2011-01-25 Medicament for treating diabetes mellitus
GB1116852.3A GB2487616A (en) 2011-01-25 2011-09-30 Plant-based drug for diabetes

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2487616A (en) * 2011-01-25 2012-08-01 qi ling Wang Plant-based drug for diabetes
CN105055967A (en) * 2015-08-31 2015-11-18 刘艳华 Compound health care product having auxiliary blood sugar reducing function and preparation method
CN105477102A (en) * 2015-12-18 2016-04-13 吴福 Traditional Chinese medicine for treating type 2 diabetes
CN105833019A (en) * 2016-03-21 2016-08-10 东莞市东卓中天生物科技有限公司 Health care product for treatment of diabetes and preparation method thereof
CN106215043A (en) * 2016-09-06 2016-12-14 福建虎伯寮药业有限责任公司 A kind of roxburgh anoectochilus terminal bud buccal tablet with effect of lowering blood sugar and preparation method thereof
CN108853339A (en) * 2018-09-20 2018-11-23 东莞市东卓中天生物科技有限公司 A kind of Chinese medicine composition for treating diabetes
CN108968042A (en) * 2018-06-27 2018-12-11 桐城市泰安中药材种植专业合作社 A kind of health care product and its processing method for reducing blood glucose

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2487616A (en) * 2011-01-25 2012-08-01 qi ling Wang Plant-based drug for diabetes
CN105055967A (en) * 2015-08-31 2015-11-18 刘艳华 Compound health care product having auxiliary blood sugar reducing function and preparation method
CN105055967B (en) * 2015-08-31 2019-02-19 刘艳华 A kind of complex health care product and preparation method with auxiliary hyperglycemic function
CN105477102A (en) * 2015-12-18 2016-04-13 吴福 Traditional Chinese medicine for treating type 2 diabetes
CN105833019A (en) * 2016-03-21 2016-08-10 东莞市东卓中天生物科技有限公司 Health care product for treatment of diabetes and preparation method thereof
CN106215043A (en) * 2016-09-06 2016-12-14 福建虎伯寮药业有限责任公司 A kind of roxburgh anoectochilus terminal bud buccal tablet with effect of lowering blood sugar and preparation method thereof
CN108968042A (en) * 2018-06-27 2018-12-11 桐城市泰安中药材种植专业合作社 A kind of health care product and its processing method for reducing blood glucose
CN108853339A (en) * 2018-09-20 2018-11-23 东莞市东卓中天生物科技有限公司 A kind of Chinese medicine composition for treating diabetes

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Application publication date: 20110622