CN105832885A - Traditional Chinese medicine composition for treating insomnia - Google Patents

Traditional Chinese medicine composition for treating insomnia Download PDF

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CN105832885A
CN105832885A CN201610276971.8A CN201610276971A CN105832885A CN 105832885 A CN105832885 A CN 105832885A CN 201610276971 A CN201610276971 A CN 201610276971A CN 105832885 A CN105832885 A CN 105832885A
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chinese medicine
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朱增伟
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Abstract

Provided is a traditional Chinese medicine composition for treating insomnia .The traditional Chinese medicine composition is prepared from radix angelicae sinensis, rhizoma chuanxiong, radix bupleuri, radix polygalae, seman platycladi, cortex moutan, radix achyranthis bidentatae, pheretima, radix paeoniae alba, semen ziziphi spinosae, rhizoma atractylodis macrocephalae, poria cocos, radix scrophulariae, radix notoginseng, Chinese dates and licorice roots .The ingredients of the traditional Chinese medicine composition all adopt natural traditional Chinese medicinal raw materials, preparation is easy and convenient, the medicine source is wide, the cost is low, all the raw materials in the ingredients are combined together, the medical efficacy can be exerted to the maximum extent, the balance of yin and yang and the self-coordination capacity of the organism of a patient can be effectively adjusted, the effects of benefiting qi for promoting production of body fluid, nourishing blood for tranquillization, tonifying the kidney and calming the heart are achieved, and the purpose of treating both manifestation and root causes of diseases is achieved .The absorption effect is good, the curative effect is significant, no side effect exists, and the safety is high.

Description

The Chinese medicine composition for the treatment of insomnia
Technical field
The present invention relates to a kind of Chinese medicine composition, more particularly to a kind of Chinese medicine composition treating insomnia, belong to tcm field.
Background technology
Sleep is the important physiological activity maintaining health, and healthy sleep can improve immunity of organisms, strengthen the ability of resist the disease, corticosteroid can be made to keep naturally circulation, make people in high spirits.Insomnia is to have difficulty in going to sleep and maintain dyskoimesis to be characterized, and often shows as being difficult to falling asleep, can not fall asleep, maintains dyskoimesis, too early or intermittence is waken up and caused and do not have enough sleep.Insomnia is a kind of modal sleep disordered, and almost everyone ats fault the experience slept.Along with the development of society, the quickening of rhythm of life, the incidence rate of insomnia is on the rise.
Insomnia is sick, and main in modern clinic based on Western medicine, insomnia patients needs to take medicine all the life, and due to long-term taking chemical agent, the organ such as the heart of human body, brain, kidney is by infringement in various degree.Along with the growth of your there, body forms toleration to medicine, and the medication amount taken needs to increase, and has deepened the infringement to body further.
Summary of the invention
For the problem of above-mentioned existence, the present invention provides the Chinese medicine composition for the treatment of insomnia, and this Chinese medicine composition can effectively be treated the insomnia that a variety of causes causes, be had no side effect, difficulty in relapse after healing of fullying recover from an illness.
For achieving the above object, the present invention adopts the technical scheme that, the Chinese medicine composition for the treatment of insomnia, is made up of the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 10--20 part, Rhizoma Chuanxiong 10--20 part, Radix Bupleuri 20--25 part, Radix Polygalae 20--30 part, Semen Platycladi 20--30 part, Cortex Moutan 8-10 part, Radix Achyranthis Bidentatae 10--15 part, Pheretima 8--10 part, Radix Paeoniae Alba 10--15 part, Semen Ziziphi Spinosae 20--40 part, Rhizoma Atractylodis Macrocephalae 5--10 part, Poria 20--40 part, Radix Scrophulariae 20--30 part, Radix Notoginseng 5--10 part, Fructus Jujubae 15--20 part, Radix Glycyrrhizae 5--10 part.
It is preferably, the Chinese medicine composition for the treatment of insomnia, is made up of the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 15 parts, Radix Bupleuri 20 parts, Radix Polygalae 25 parts, Semen Platycladi 25 parts, Cortex Moutan 8 parts, Radix Achyranthis Bidentatae 12 parts, Pheretima 10 parts, the Radix Paeoniae Alba 12 parts, Semen Ziziphi Spinosae 30 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, 30 parts of Poria, Radix Scrophulariae 25 parts, Radix Notoginseng 8 parts, 20 parts of Fructus Jujubae, 8 parts of Radix Glycyrrhizae.
Radix Angelicae Sinensis: sweet in the mouth, pungent, bitter, warm in nature;Return liver, the heart, spleen channel;There is replenishing and activating blood, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature;Return liver, gallbladder, pericardium channel;There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.
Radix Bupleuri: bitter in the mouth, cold nature;Return liver, gallbladder meridian;Having with in table solution, dispersing the stagnated live-QI to relieve the stagnation of QI, liter lifts effect of yang-energy.
Radix Polygalae: bitter in the mouth, pungent, warm in nature;GUIXIN, kidney, lung meridian;There is mind tranquilizing and the heart calming, expelling phlegm for arresting cough, effect of reducing swelling and alleviating pain.
Semen Platycladi: sweet in the mouth, property is put down;GUIXIN, kidney, large intestine channel;There is tranquilizing by nourishing the heart, effect of loosening bowel to relieve constipation.
Cortex Moutan: bitter in the mouth, pungent, cold nature;GUIXIN, liver, kidney channel;There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.
Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is put down;Return liver, kidney channel;There is invigorating the liver and kidney, ask muscles and bones, promoting blood circulation to restore menstrual flow, conducting blood to flow downwards, effect of inducing diuresis for treating stranguria syndrome.
Pheretima: salty in the mouth, cold in nature;Return liver, lung, kidney channel;There is heat clearing away relieving convulsion, suppressing the hyperactive liver to relieve the wind syndrome, dredge the meridian passage, effect of level land diuresis.
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature;Return liver, spleen channel;Have and nourish blood and seek, easing the affected liver to relieve pain, effect of suppressing liver-YANG.
Semen Ziziphi Spinosae: sweet in the mouth, acid, property is put down;Return liver, gallbladder, heart channel;There is the tonifying liver that nourishes heart, mind tranquilizing and the heart calming, arresting sweating, the effect promoted the production of body fluid.
The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, hardship, warm in nature;Return spleen, stomach warp;There is invigorating the spleen and benefiting QI, dampness diuresis, hidroschesis, antiabortive effect.
Poria: sweet in the mouth, light, property is put down;GUIXIN, lung, spleen, kidney channel;There is promoting diuresis to eliminate damp pathogen, spleen invigorating and in, effect of mind tranquilizing and the heart calming.
Radix Scrophulariae: bitter in the mouth, sweet, salty, cold nature;Return spleen, stomach, kidney channel;There is clearing away heat and cooling blood, nourishing YIN to lower pathogenic fire, effect of detoxicating and resolving stagnation of pathogens.
Radix Notoginseng: sweet in the mouth, micro-hardship, warm in nature;Return liver, stomach warp;There is dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.
Fructus Jujubae: sweet in the mouth, warm in nature;Return spleen, stomach warp;There is air making-up and spleen enlivening, nourishing blood to tranquillize the mind, harmonizing yingfen and weifen, relax effect of the property of medicine.
Radix Glycyrrhizae: sweet in the mouth, property is put down;Return spleen, stomach, lung, heart channel;There is QI invigorating invigorating middle warmer, expelling phlegm for arresting cough, heat-clearing and toxic substances removing, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.
Its preparation method is: put in container by above-mentioned raw material of Chinese medicine, and added water no powder, soaks 10 15 minutes, added water no powder 58 centimetres, carries out decocting for the first time, decocts with high heat before not boiling, with slow fire boiling 15 20 minutes after boiling;When second time decocts, added water no powder 58 centimetres, decocts with high heat, with slow fire boiling 15 20 minutes after water boiling;Decocting extracting juice twice, merging is taken.
The present composition has carried out substantial amounts of animal acute toxicity test, long-term toxicity test for animals and a large amount of clinical trials for the treatment of disease, and the use link that this medicine puts into treatment disease provides science and objective foundation.Its result of the test is as follows:
(1) decoction preparing the present invention carries out animal acute toxicity test, takes white mice 10, and male and female have both, body weight 40 60g, hungry 15 20 hours, every every natural gift fill for 3 times fed 20 25ml, fills continuously and feeds one week, observes 14 days, white mice is movable normal, non-toxic reaction, without dead;Show that oral liquid is without acute toxicity, clinical medicine dose safety.
(2) decoction preparing the present invention carries out long-term toxicity test for animals, take rat 40, male and female have both, body weight 120 150g, it is divided into two groups, often group 20, wherein first group as administration group, feed by filling for 2 times every every day, each 5 10ml, second group of diet is as a control group, once a day, fill continuously and feed 100 days, survey body weight, it is administered 24 hours sacrificed by decapitation in last, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, all non-toxic reactions, it is a kind of safe drugs.
The component of this Chinese medicine composition all uses natural raw material of Chinese medicine, its preparation is easy, medicine source is wide, low cost, various material medicines in component are mutually coordinated together, can play and farthest play drug effect, can effectively regulate equilibrium between yin and yang and the self-coordination ability of patient's body, there is effect of supplementing QI for promoting the production of body fluid, nourishing blood to tranquillize the mind, kidney calming, thus reach the purpose for the treatment of both the principal and secondary aspects of a disease;And good absorbing effect, evident in efficacy, have no side effect, safety is high.
Below in conjunction with clinical data and model case, beneficial effects of the present invention is further illustrated.
One, diagnosis basis: with reference to the diagnostic criteria of insomnia in People's Republic of China's traditional Chinese medicine industry standard " disease of tcm Standardization of diagnosis and curative effect ":
The diseases such as 1. the lighter's difficulty of falling asleep or sleep but easy to wake, is insomnia after waking up, dreaminess;
2. headache it is often accompanied by, dizzy, cardiopalmus, forgetful, the disease such as dreaminess;
3. no abnormal through each system and lab testing.
Two, general data
Use the Chinese medicine composition of the treatment insomnia that the present invention provides from January, 2012--treat insomniac 147 people, wherein male 71 people in January, 2015, women 76 people, age 14--70 year, the shortest person of the course of disease 3 months, elder 8 years, average 3 years.
Three, Therapeutic Method
Use the decoction prepared by Chinese medicine composition of the present invention, every day the most each oral once, within 7 days, be a course for the treatment of.
Four, Outcome measure
Cure: easily fall asleep or sleep recovers normal, transference cure, the length of one's sleep more than 67.
Effective: the length of one's sleep is obviously prolonged, sleep is easier to, symptom SPR.
Effective: still can fall asleep after treatment, simultaneous phenomenon alleviates earlier above.
Invalid: after treatment, sleep state and symptom have no improvement.
Five, therapeutic outcome
In clinical observation case, take medicine 1--4 the course for the treatment of, cure 141 people, account for 95.9%;Effective 3 people, account for 2.0%;Effective 2 people, account for 1.3%;Invalid 1 people, accounts for 0.06%;Total effective rate is 99.3%.
Six, model case
Case 1
Zhao, man, 65 years old, patient's private prosecution suffered from insomnia about 2 years, the most often headache, dizzy, feeling of fullness in the head, has difficulty in going to sleep every night, easily wakes up after sleeping, cannot fall asleep, with dizziness and tinnitus, hypomnesis, Sleep hyperhidrosis, irascible temperament, anorexia after waking up again.Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, difficulty falling asleep symptom substantially alleviates, and improves with symptom, continues again to take 3 courses for the treatment of, dizziness and tinnitus etc. with transference cure, sleep recovers normal, cures.
Case 2
Di, female, 45 years old, suffer from insomnia 5 years, the length of one's sleep 34 hours every night, energy of waking up is not good, fatigue and weakness, Light-headedness, dreaminess during sleep, anorexia.After one course for the treatment of of medicament taking prepared by Chinese medicine composition of the present invention, patient sleeps improves, relatively before easily fall asleep, after continuing again to take 3 courses for the treatment of, malaise symptoms is wholly absent, every night the length of one's sleep more than 7 hours, sleep quality significantly improves, hale and hearty after waking up, and patient fully recovers.
Case 3
Zhang, man, 41 years old, suffer from insomnia 2 years, night, difficulty falling asleep, easily woke up after sleeping, and daytime, lethargy was depressed, listless, and health is weak, and with dizzy, the symptom of feeling of fullness in the head.Taking 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, sleep quality is obviously prolonged, and continues again to take 2 courses for the treatment of, can go to sleep peacefully every night more than 7 hours, and dizzy, the symptom of feeling of fullness in the head is also wholly absent, and daytime is hale and hearty, follows up a case by regular visits to 1 year have no recurrence.
Detailed description of the invention
Embodiment 1
The Chinese medicine composition for the treatment of insomnia, is made up of the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 18 parts, Radix Bupleuri 22 parts, Radix Polygalae 25 parts, Semen Platycladi 25 parts, Cortex Moutan 10 parts, Radix Achyranthis Bidentatae 10 parts, Pheretima 10 parts, the Radix Paeoniae Alba 15 parts, Semen Ziziphi Spinosae 35 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, 35 parts of Poria, Radix Scrophulariae 25 parts, Radix Notoginseng 10 parts, 20 parts of Fructus Jujubae, 6 parts of Radix Glycyrrhizae.
Its preparation method is: put in container by above-mentioned raw material of Chinese medicine, and added water no powder, soaks 10 15 minutes, added water no powder 58 centimetres, carries out decocting for the first time, decocts with high heat before not boiling, with slow fire boiling 15 20 minutes after boiling;When second time decocts, added water no powder 58 centimetres, decocts with high heat, with slow fire boiling 15 20 minutes after water boiling;Decocting extracting juice twice, merging is taken.
Embodiment 2
The Chinese medicine composition for the treatment of insomnia, is made up of the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 18 parts, Radix Bupleuri 22 parts, Radix Polygalae 22 parts, Semen Platycladi 22 parts, Cortex Moutan 10 parts, Radix Achyranthis Bidentatae 14 parts, Pheretima 10 parts, the Radix Paeoniae Alba 14 parts, Semen Ziziphi Spinosae 30 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 35 parts of Poria, Radix Scrophulariae 25 parts, Radix Notoginseng 10 parts, 15 parts of Fructus Jujubae, 8 parts of Radix Glycyrrhizae.
Its preparation method is: put in container by above-mentioned raw material of Chinese medicine, and added water no powder, soaks 10 15 minutes, added water no powder 58 centimetres, carries out decocting for the first time, decocts with high heat before not boiling, with slow fire boiling 15 20 minutes after boiling;When second time decocts, added water no powder 58 centimetres, decocts with high heat, with slow fire boiling 15 20 minutes after water boiling;Decocting extracting juice twice, merging is taken.
Embodiment 3
The Chinese medicine composition for the treatment of insomnia, is made up of the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 16 parts, Radix Bupleuri 23 parts, Radix Polygalae 28 parts, Semen Platycladi 28 parts, Cortex Moutan 10 parts, Radix Achyranthis Bidentatae 12 parts, Pheretima 8 parts, the Radix Paeoniae Alba 12 parts, Semen Ziziphi Spinosae 30 parts, the Rhizoma Atractylodis Macrocephalae 9 parts, 32 parts of Poria, Radix Scrophulariae 25 parts, Radix Notoginseng 5 parts, 16 parts of Fructus Jujubae, 8 parts of Radix Glycyrrhizae.
Its preparation method is: put in container by above-mentioned raw material of Chinese medicine, and added water no powder, soaks 10 15 minutes, added water no powder 58 centimetres, carries out decocting for the first time, decocts with high heat before not boiling, with slow fire boiling 15 20 minutes after boiling;When second time decocts, added water no powder 58 centimetres, decocts with high heat, with slow fire boiling 15 20 minutes after water boiling;Decocting extracting juice twice, merging is taken.
Embodiment 4
The Chinese medicine composition for the treatment of insomnia, is made up of the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 14 parts, Rhizoma Chuanxiong 14 parts, Radix Bupleuri 20 parts, Radix Polygalae 24 parts, Semen Platycladi 24 parts, Cortex Moutan 9 parts, Radix Achyranthis Bidentatae 11 parts, Pheretima 9 parts, the Radix Paeoniae Alba 14 parts, Semen Ziziphi Spinosae 36 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, 36 parts of Poria, Radix Scrophulariae 24 parts, Radix Notoginseng 7 parts, 18 parts of Fructus Jujubae, 6 parts of Radix Glycyrrhizae.
Its preparation method is: put in container by above-mentioned raw material of Chinese medicine, and added water no powder, soaks 10 15 minutes, added water no powder 58 centimetres, carries out decocting for the first time, decocts with high heat before not boiling, with slow fire boiling 15 20 minutes after boiling;When second time decocts, added water no powder 58 centimetres, decocts with high heat, with slow fire boiling 15 20 minutes after water boiling;Decocting extracting juice twice, merging is taken.

Claims (2)

1. the Chinese medicine composition for the treatment of insomnia, is made up of the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 10--20 part, Rhizoma Chuanxiong 10--20 part, Radix Bupleuri 20--25 part, Radix Polygalae 20--30 part, Semen Platycladi 20--30 part, Cortex Moutan 8-10 part, Radix Achyranthis Bidentatae 10--15 part, Pheretima 8--10 part, Radix Paeoniae Alba 10--15 part, Semen Ziziphi Spinosae 20--40 part, Rhizoma Atractylodis Macrocephalae 5--10 part, Poria 20--40 part, Radix Scrophulariae 20--30 part, Radix Notoginseng 5--10 part, Fructus Jujubae 15--20 part, Radix Glycyrrhizae 5--10 part.
The Chinese medicine composition for the treatment of insomnia the most according to claim 1, is made up of the Chinese medicine of following parts by weight: Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 15 parts, Radix Bupleuri 20 parts, Radix Polygalae 25 parts, Semen Platycladi 25 parts, Cortex Moutan 8 parts, Radix Achyranthis Bidentatae 12 parts, Pheretima 10 parts, the Radix Paeoniae Alba 12 parts, Semen Ziziphi Spinosae 30 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, 30 parts of Poria, Radix Scrophulariae 25 parts, Radix Notoginseng 8 parts, 20 parts of Fructus Jujubae, 8 parts of Radix Glycyrrhizae.
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CN112022997A (en) * 2020-09-16 2020-12-04 孝感开发区和一堂中医门诊部 Acupoint application medicine for treating insomnia and preparation method thereof

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CN103463354A (en) * 2013-08-27 2013-12-25 冯庆云 Traditional Chinese medicine composition for treating insomnia
CN103751318A (en) * 2014-01-20 2014-04-30 于建梅 Traditional Chinese medicinal composition for treating insomnia caused by lack of spirit preservation
CN104906226A (en) * 2015-06-12 2015-09-16 王中杰 Traditional Chinese medicine composition for treating insomnia

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CN1493353A (en) * 2003-09-18 2004-05-05 江苏扬子江药业集团有限公司 Chinese compound medicine for treating anhypnosis and its preparation metod
CN103028034A (en) * 2011-09-30 2013-04-10 彭军 Pharmaceutical composition for treating insomnia and preparation method
CN103463354A (en) * 2013-08-27 2013-12-25 冯庆云 Traditional Chinese medicine composition for treating insomnia
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112022997A (en) * 2020-09-16 2020-12-04 孝感开发区和一堂中医门诊部 Acupoint application medicine for treating insomnia and preparation method thereof

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