CN106177495A - Chinese medicine composition for the treatment of diabetes and preparation method thereof - Google Patents

Chinese medicine composition for the treatment of diabetes and preparation method thereof Download PDF

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CN106177495A
CN106177495A CN201610656811.6A CN201610656811A CN106177495A CN 106177495 A CN106177495 A CN 106177495A CN 201610656811 A CN201610656811 A CN 201610656811A CN 106177495 A CN106177495 A CN 106177495A
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weight portion
radix
diabetes
chinese medicine
rhizoma
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吴邵军
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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Abstract

Chinese medicine composition for the treatment of diabetes and preparation method thereof, belongs to technical field of Chinese medicines.It is an object of the invention to how to provide that a kind of instant effect, short treating period, therapeutic effect are good, toxic and side effects is little, be difficult to Chinese medicine composition for the treatment of diabetes repeatedly and preparation method thereof.The Chinese medicine composition of the present invention, containing Radix Et Rhizoma Rhei, Radix Glycyrrhizae Preparata, Radix Scutellariae, Radix Rehmanniae Preparata, Rhizoma Dioscoreae, Radix Adenophorae (Radix Glehniae), Rhizoma Coptidis, the Rhizoma Anemarrhenae, Radix Ophiopogonis, Rhizoma Polygonati, Fructus Lycii, Rhizoma Polygonati Odorati, Rhizoma Atractylodis, Cortex Phellodendri, Fructus Schisandrae Chinensis, Radix Codonopsis, Radix Puerariae, Radix Trichosanthis, Radix Astragali, Herba Potentillae Discoloris, fevervine, Semen Sojae Preparatum, Hirudo, Radix Notoginseng, Radix Et Caulis Acanthopanacis Senticosi seed, Herba Dendrobii, Ramulus Euonymi, Herba Apocyni veneti and Folium Ginkgo 29 taste Chinese medicine.This Chinese medicine composition has short treating period, has no side effect, is difficult to advantage repeatedly, and primary diabetes mellitus, secondary diabetes and diabetic complication are all had preferable therapeutic effect, and effective percentage can reach more than 90%.

Description

Chinese medicine composition for the treatment of diabetes and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition treating diabetes and preparation method thereof.
Background technology
Diabetes (diabetes mellitus) are a kind of metabolic diseases being characterized with hyperglycemia, and clinical manifestation is Typical " three-many-one-little " symptom occurs.
Diabetes inducement thinks that, by gene, environment is bad, immunodeficiency more, and meals are unreasonable, and daily life is irregular, essence God's irriate, the insulin that the many factors such as spleen, liver and renal disorder causes is definitely or relative detuning.Diabetes are controlled at present Treat still based on chemical synthetic drug, such as sulfonamides, double flesh class, glucose former times enzyme inhibitor, Lie Nai and euglycemic agent etc.. But these are all Western medicine, i.e. organic chemical, although quick result, but human body can be caused a lot of untoward reaction, great majority Diabetics need to take medicine all the life, medicine long-term taking side effect is the biggest, there is application risk.The invention of insulin With extensively application, it is clear that solve the misery of most patient, but it is still that and will be mended the day after tomorrow, rely on all the life, control table and do not effect a permanent cure, lead Cause the generation of multiple complications.
Chinese medicine think diabetes mainly due to the ferritic deficiency of YIN, the five internal organs are weak, multiple because of eating and drinking without temperance, surfeit delicious food, feelings Will is lacked of proper care, and labor is intended to excessively, and causes deficiency of kidney-YIN, lung dryness of the stomach heat;Pathogenesis emphasis is that the deficiency of YIN is scorching, and with the deficiency of YIN for this, scorching For table;With the passing of time disease prolongs, deficiency of YIN affecting YANG, deficiency in both YIN and YANG;The deficiency of YIN is scorching, and consumption Tianjin liquid that burns makes blood viscous, blood is not smooth form tired;Cloudy Undermine sun, yang deficiency cold coagulation, also may result in sun in tired blood.Chinese medicine has long history, Jing Guoji in terms of preventing and treating diabetes The practice of thousand, have accumulated substantial amounts of invaluable experience, defines the Scientific systems of uniqueness.Chinese medicine ancient books and records describe much to be had The Chinese medicine of blood sugar lowering curative effect, such as Rhizoma Alismatis, the Rhizoma Anemarrhenae, Radix Panacis Quinquefolii, Radix Puerariae, Radix Rehmanniae, pollen etc..In prior art, there is recurrence due to taking drug in some Side's Remedies for diabetes, this kind of medicine has certain help for diabetes-alleviating, but poor effect.
Summary of the invention
It is an object of the invention to how to provide a kind of instant effect, short treating period, therapeutic effect is good, toxic and side effects is little, be difficult to anti- Multiple Chinese medicine composition for the treatment of diabetes and preparation method thereof.
The Chinese medicine composition for the treatment of diabetes, forms and weight proportion is: Radix Et Rhizoma Rhei 20-40 weight portion, Radix Glycyrrhizae Preparata 20-40 weight Amount part, Radix Scutellariae 35-55 weight portion, Radix Rehmanniae Preparata 35-55 weight portion, Rhizoma Dioscoreae 40-60 weight portion, Radix Adenophorae (Radix Glehniae) 30-50 weight portion, Rhizoma Coptidis 35-55 weight portion, Rhizoma Anemarrhenae 35-55 weight portion, 35-55 weight portion Radix Ophiopogonis, Rhizoma Polygonati 35-55 weight portion, Fructus Lycii 35-55 weight portion, Rhizoma Polygonati Odorati 35-55 weight portion, Rhizoma Atractylodis 35-55 weight portion, Cortex Phellodendri 35-55 weight portion, Fructus Schisandrae Chinensis 35-55 weight portion, Radix Codonopsis 35-55 weight Amount part, Radix Puerariae 55-70 weight portion, Radix Trichosanthis 55-70 weight portion, Radix Astragali 55-70 weight portion, Herba Potentillae Discoloris 55-70 weight portion, chicken Vow rattan 55-70 weight portion, Semen Sojae Preparatum 55-70 weight portion, Hirudo 55-70 weight portion, Radix Notoginseng 55-70 weight portion, Radix Et Caulis Acanthopanacis Senticosi seed 40- 60 weight portions, Herba Dendrobii 20-40 weight portion, Ramulus Euonymi 55-70 weight portion, Herba Apocyni veneti 55-70 weight portion, Folium Ginkgo 40-55 Weight portion.
Preferably, described composition and weight proportion are: Radix Et Rhizoma Rhei 30 weight portion, Radix Glycyrrhizae Preparata 30 weight portion, Radix Scutellariae 45 weight portion, Radix Rehmanniae Preparata 45 weight portion, Rhizoma Dioscoreae 50 weight portion, Radix Adenophorae (Radix Glehniae) 40 weight portion, Rhizoma Coptidis 45 weight portion, the Rhizoma Anemarrhenae 45 weight portion, weight Radix Ophiopogonis 45 Part, Rhizoma Polygonati 45 weight portion, Fructus Lycii 45 weight portion, Rhizoma Polygonati Odorati 45 weight portion, Rhizoma Atractylodis 45 weight portion, Cortex Phellodendri 45 weight portion, Fructus Schisandrae Chinensis 45 Weight portion, Radix Codonopsis 45 weight portion, Radix Puerariae 60 weight portion, Radix Trichosanthis 60 weight portion, Radix Astragali 60 weight portion, Herba Potentillae Discoloris 60 weight Part, fevervine 60 weight portion, Semen Sojae Preparatum 60 weight portion, Hirudo 60 weight portion, Radix Notoginseng 60 weight portion, Radix Et Caulis Acanthopanacis Senticosi seed 50 weight portion, Herba Dendrobii 30 weight portion, Ramulus Euonymi 60 weight portion, Herba Apocyni veneti 60 weight portion, Folium Ginkgo 45 weight portion.
Preferably, the Chinese medicine composition of described treatment diabetes is powder or watered pill.
Preferably, the Chinese medicine composition of described treatment diabetes is powder, and fineness is 80-100 mesh.
Preferably, the Chinese medicine composition of described treatment diabetes is watered pill, and particle diameter is 2-2.5mm.
The preparation method of the Chinese medicine composition of above-mentioned treatment diabetes, is weighting raw materials by weight ratio, grinds into thin Powder, sieves, mixing, the Chinese medicine composition of the diabetes that obtain medical treatment.
The preparation method of the Chinese medicine composition of above-mentioned treatment diabetes, is weighting raw materials by weight ratio, adds the watered pill Machine, makes watered pill, the Chinese medicine composition of the diabetes that obtain medical treatment.
Preferably, the mixture that slurry is starch and water that described machine for making water-bindered pills uses;The rate of charge of machine for making water-bindered pills is: starch Quality, water quality, crude drug gross mass are 5:95:5.
Compared with prior art, beneficial effects of the present invention:
The Chinese medicine composition of the treatment diabetes of the present invention is combined by plurality of Chinese, acts on the devices such as spleen, liver and kidney Official, thus activate Stem Cells, endocrine regulation, repair Stem Cells, make the saccharide of body cell, protein, fat normal Metabolism, fundamentally treatment diabetes and the multiple syndrome caused by diabetes, overcome use antidiabetic drug and insulin is controlled Treat diabetes, it is impossible to the fundamentally defect of repairing islet cells, there is short treating period, have no side effect, be difficult to advantage repeatedly, According to clinical verification, the treated effect of primary diabetes mellitus and secondary diabetes can be reached by the Chinese medicine composition of the present invention More than 90%.
The preparation method of the Chinese medicine composition of the treatment diabetes of the present invention is simple, does not has special process, it is simple to produce.
Detailed description of the invention
In order to further appreciate that the present invention, below in conjunction with detailed description of the invention, the preferred embodiments of the invention are retouched State, but it is to be understood that these describe simply as further illustrating the features and advantages of the present invention rather than to patent of the present invention The restriction required.
The Chinese medicine composition for the treatment of diabetes, forms and weight proportion is: Radix Et Rhizoma Rhei 20-40 weight portion, Radix Glycyrrhizae Preparata 20-40 weight Amount part, Radix Scutellariae 35-55 weight portion, Radix Rehmanniae Preparata 35-55 weight portion, Rhizoma Dioscoreae 40-60 weight portion, Radix Adenophorae (Radix Glehniae) 30-50 weight portion, Rhizoma Coptidis 35-55 weight portion, Rhizoma Anemarrhenae 35-55 weight portion, 35-55 weight portion Radix Ophiopogonis, Rhizoma Polygonati 35-55 weight portion, Fructus Lycii 35-55 weight portion, Rhizoma Polygonati Odorati 35-55 weight portion, Rhizoma Atractylodis 35-55 weight portion, Cortex Phellodendri 35-55 weight portion, Fructus Schisandrae Chinensis 35-55 weight portion, Radix Codonopsis 35-55 weight Amount part, Radix Puerariae 55-70 weight portion, Radix Trichosanthis 55-70 weight portion, Radix Astragali 55-70 weight portion, Herba Potentillae Discoloris 55-70 weight portion, chicken Vow rattan 55-70 weight portion, Semen Sojae Preparatum 55-70 weight portion, Hirudo 55-70 weight portion, Radix Notoginseng 55-70 weight portion, Radix Et Caulis Acanthopanacis Senticosi seed 40- 60 weight portions, Herba Dendrobii 20-40 weight portion, Ramulus Euonymi 55-70 weight portion, Herba Apocyni veneti 55-70 weight portion, Folium Ginkgo 40-55 Weight portion.
In the Chinese medicine composition of the present invention, 29 taste Chinese medicines are all field of Chinese medicines medicinal herbs most in use, can pass through art technology Personnel's usual way obtains:
Radix Et Rhizoma Rhei, source: for the rhizome of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.Select between the 9-10 month Grow the plant of more than 3 years, take rhizome, excise stem and leaf, supporting root, scrape off rough bark and terminal bud, air-dry, dry or cut into slices and dry. Function cures mainly: purge heat poison, and removing mass is stagnant, clots absorbing blood.Controlling excess-heat constipation, delirium sends out torr, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, Stasis of blood menolipsis is closed, lump in the abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spit blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, also urinate, carbuncle and ulcer toxic swelling, furuncle Skin ulcer, burn.
Radix Glycyrrhizae Preparata, source: for the Preparation process product of Radix Glycyrrhizae.Function cures mainly: spleen reinforcing stomach function regulating, Yiqi and vein recovery.Weakness of the spleen and stomach, tired Idle weak, severe palpitation, irregularly intermittent and regularly intermittent pulse.
Radix Scutellariae, source: for the root of labiate Radix Scutellariae.Spring to early summer gathers (autumn also can).Choosing growth 3-4's Plant.Remove stem Seedling, fibrous root and earth after being dug out by root, shine to hitting cork time half-dried, then shine to absolutely dry.Function cures mainly: rush down Excess-fire, dehumidifying heat, hemostasis, antiabortive.Control high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tell, be defeated in battle, collapse, leak, conjunctival congestion Swell and ache, frequent fetal movement, carbuncle furuncle.
Radix Rehmanniae Preparata, source: for scrophulariaceae rehmannia glutinosa plant or the rhizome of bosom celebrating Radix Rehmanniae, processed steaming is shone and formed.Function cures mainly: YIN nourishing, enriches blood.Control deficiency of YIN insufficiency of blood, waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency, seminal emission, metrorrhagia, menoxenia, quench one's thirst, frequency of micturition, deaf, mesh Dusk.
Rhizoma Dioscoreae, source: for the tuber of Dioscoreaceae plant Rhizoma Dioscoreae.The 11-12 month excavates, and cuts root head, cleans earth, uses bamboo knife Scrape off crust, dry or dry, be a mao Rhizoma Dioscoreae.Select thick hair Rhizoma Dioscoreae, even with clear water leaching, then add slight fever, and use cotton-wadded quilt Build, keep moistening vexed, be then placed on and crumple into cylindric on plank, two is trimmed, dries polishing, be light yam. Function cures mainly: spleen invigorating, and tonifying the lung is reinforced the kidney, benefit essence.Control diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quench one's thirst, seminal emission, leukorrhagia, urine frequency Number.
Radix Adenophorae (Radix Glehniae), source: for campanulaceae Lady bell plant four leaf Radix Adenophorae (Radix Glehniae), Folium Pruni Radix Adenophorae (Radix Glehniae) or its congener, be used as medicine with root.Autumn Season, plane adopted, and removes aerial parts and fibrous root, scrapes off rough bark, immediately dry.Function cures mainly: clearing away heat and nourishing YIN, nourishing the lung to arrest cough.Cure mainly gas Guan Yan, pertussis, cough due to lung-heat, coughs up phlegm yellow thick.
Rhizoma Coptidis, source: for the rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao, coptis omeiensis or Coptis teeta.With the Beginning of Winter Afterwards (November) gather and be advisable.Remove stem and leaf, fibrous root and earth after excavating, dry or dry, hit rough bark.Function cures mainly: pathogenic fire purging, Dampness, removing toxic substances, parasite killing.Row pyretic toxicity when controlling, typhoid fever, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, and lung knot is pressed, tell, be defeated in battle, Hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.
The Rhizoma Anemarrhenae, source: for the rhizome of the liliaceous plant Rhizoma Anemarrhenae.Spring, autumn all can excavate, and with autumn, the person of adopting is preferable.Cultivation three Results are started after Nian.Dig out rhizome, remove stem Seedling and fibrous root, retain yellow fine hair and lurid leaf scar and the stem trace person of drying, for " RHIZOMA ANEMARRHENAE with peet ";The cork person of drying is peelled off for " RHIZOMA ANEMARRHENAE " time fresh.Function cures mainly: nourishing YIN to lower pathogenic fire, moisturizes laxation.Control dysphoria with smothery sensation to quench one's thirst, bone Steam consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.
Radix Ophiopogonis, function cures mainly: YIN nourishing and the production of body fluid promoting, nourishing the lung to arrest cough: few thirsty, dry cough spitting of blood for Tianjin of lung-stomach yin deficiency;The heart-yin The palpitation and being susceptible to fright of deficiency and calentura later stage consumption of body fluid by heat etc. are demonstrate,proved.Join Radix Adenophorae (Radix Glehniae), Bulbus Fritillariae Cirrhosae can control deficiency of lung-YIN dry cough.
Rhizoma Polygonati, source: for the rhizome of liliaceous plant Rhizoma Polygonati, P. cyrtonema, hot river Rhizoma Polygonati, P. kingianum, polygonatum cirrhifolium Royle etc.. Spring, autumn gather, good with the autumn person's of adopting matter.Taking rhizome, remove aerial parts and fibrous root, wash away earth, in putting food steamer, steaming is to presenting Time glossy, take out and dry or dry.Or after putting water boiling, pull out and dry or dry.Function cures mainly: invigorating the spleen and replenishing QI, moistens cardiopulmonary, Bone and muscle strengthening.Controlling deficient cold and heat, pulmonary tuberculosis hemoptysis, after being ill body void lack of appetite, muscles and bones is weak, rheumatalgia, wind favus disease.
Fructus Lycii, function cures mainly: nourishing kidney, lung moistening, tonifying liver, improving eyesight.Control hepatic and renal YIN deficiency, soreness of the waist and knees, dizzy, dizzy, blurred vision Many tears, cough due to consumptive disease, quench one's thirst, seminal emission.
Rhizoma Polygonati Odorati, source: for the rhizome of liliaceous plant Rhizoma Polygonati Odorati.Function cures mainly: yin nourishing, moisturizes, and relieving restlessness is quenched the thirst.Control calentura Cloudy wound, excessive thirst of coughing, deficient fever, rapid digestion of food is the most hungry, frequent micturition.
Rhizoma Atractylodis, source: for the rhizome of feverfew RHIZOMA ATRACTYLODIS IANCEAE or Atractylis chinensis etc..Spring, autumn all can excavate, preferably autumn. After taking rhizome, remove residual stem, fibrous root and earth, dry.Function cures mainly: spleen invigorating, dampness, resolving depression, wards off dirty.Control wet Sheng and be stranded spleen, Asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, have loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, foot Flaccidity, nyctalopia.
Cortex Phellodendri, source: for rutaceae Cortex Phellodendri or the bark of wampee.Function cures mainly: heat clearing away.Dampness, pathogenic fire purging, solve Poison.Control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice, flaccidity, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, also under leucorrhea, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, Aphtha of the mouth and tongue, sore swollen toxin.
Fructus Schisandrae Chinensis, source: for the fruit of Drymotaenium miyoshianum (Mak.) Mak. kind plant Fructus Schisandrae Chinensis.Pluck during fruit full maturity after the Frost's Descent, pick fruit Branch and impurity, dry;Storage is dried ventilation, prevents from going rotten, damaging by worms.Function cures mainly: astringe the lung, and nourishing kidney is promoted the production of body fluid, and receives antiperspirant, arresting seminal emission. Controlling the deficiency of the lung to breath with cough, xerostomia is made thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.
Radix Codonopsis, source: for the root of Campanulaceae Radix Codonopsis.Function cures mainly: invigorating middle warmer, and QI invigorating is promoted the production of body fluid.Control weakness of the spleen and stomach, gas Blood two loses, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.
Radix Puerariae, source: for the tuber of leguminous plant Pueraria lobota.Function cures mainly: yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness only temperature.Cure the wound Cold, warm headache stiffness of the nape, dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery, and skin eruption is impermeable, hypertension, angina pectoris, deaf.
Radix Trichosanthis, source: for the root of cucurbitaceous plant Fructus Trichosanthis.Function cures mainly: promote the production of body fluid, and quenches the thirst, and pathogenic fire reducing is moisturized, evacuation of pus, disappears Swollen.Control calentura thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid complicated by anal fistula.
Radix Astragali, source: for leguminous plant Radix Astagali or Radix Astragali dry root.Spring, season in autumn two excavate, and remove fibrous root And root head, dry.Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, in Gas sink, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, and carbuncle difficulty is burst, and bursts for a long time and does not holds back, and blood deficiency dull yellowish colored skin, interior-heat disappears Yearningly;Chronic nephritis proteinuria, diabetes.
Herba Potentillae Discoloris, source: for the whole herb with root of rosaceous plant Herba Potentillae Discoloris.Summer, autumn gather.Grub out before not blooming and take, Ex-all earth, dries.Function cures mainly: heat clearing away, removing toxic substances, hemostasis, detumescence.Control dysentery, malaria, lung abscess, hemoptysis, spit blood, hematochezia, collapses Leakage, carbuncle, skin ulcer tinea, scrofula tuberculosis.
Fevervine, source: for the herb of Maguireothamnus speciosus fevervine.Gather summer herb, dry.Function cures mainly: dispel the wind Dampness removing, analgesic antidotal, promoting digestion and removing stagnation, promoting blood circulation and detumescence.For bones and muscles pain due to rheumatism, traumatic injury, traumatic pain, liver and gall and gastrointestinal The leukopenia that angor, dyspepsia, infantile malnutrition, bronchus fire, radiation reaction cause;External dermatitis, eczema and skin ulcer Infections toxic swelling.
Semen Sojae Preparatum, source: the seed for legume soybean processes through steaming net for catching birds or fish.Function cures mainly: induce sweat, relieving restlessness, a surname Strongly fragrant, removing toxic substances.The cold and heat that cure the wound are sick, cold and heat, and headache is irritated, uncomfortable in chest.
Hirudo, source: for Hirudinidae animal whitmania, Hirudo and the dry body of Folium Salicis Babylonicae Hirudo, be commonly called as Hirudo, leech.The property of medicine Salty, bitter, flat, slightly poisonous, return Liver Channel.Having removing blood stasis to stimulate the menstrual flow, removing blood stasis disappears effect, cures mainly blood stasis amenorrhea, and abdominal mass is gathered, and traumatic injury damages Wound, trusted subordinate's pain etc..
Radix Notoginseng, source: for the root of araliad Panax pseudoginseng.Function cures mainly: hemostasis, dissipating blood stasis, detumescence, analgesic therapy.Control and tell Blood, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, fall and flutter blood stasis, traumatic hemorrhage, carbuncle aches Bitterly.
Radix Et Caulis Acanthopanacis Senticosi seed, source: for dry, root and rhizome or the stem of Araliaceae Radix Et Caulis Acanthopanacis Senticosi.Spring, season in autumn two gather, and wash Only, it is dried.Function cures mainly: replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.For deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, soreness of waist and knee joint, loses Dormancy dreaminess.
Herba Dendrobii, source: for the stem of orchid Herba Dendrobii.Function cures mainly: nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst.For Consumption of body fluid caused by febrile disease, thirsty dryness of the tongue, after being ill deficiency-heat, gastropathy, retch, the few tongue of tongue light.
Ramulus Euonymi, source: for the branch of tool fin or the aliform appurtenance of Celastraceae plant winged euonymus.The whole year can adopt, and cuts After taking branch, remove twig and leaf, dry.Or collect its fin, dry.Function cures mainly: removing blood stasis, stimulates the menstrual flow, parasite killing.Control through Close, lump in the abdomen, puerperal the stagnant stomachache of the stasis of blood, abdominal pain due to worm stagnation.
Herba Apocyni veneti, source: for the herb of apocynaceae plant Herba Apocyni veneti.Function cures mainly: relieve inflammation or internal heat, blood pressure lowering, heart tonifying, diuresis. Control heart disease, hypertension, neurasthenia, hepatitis abdominal distention, nephritis edema.
Folium Ginkgo, source: for the dried leaves of Ginkgoaceae plant Ginkgo biloba (maidenhair tree, Gong Sunshu).Autumn leaf the greenest time gather, It is dried in time.Function cures mainly: astringe the lung, and relievings asthma, blood circulation promoting and blood stasis dispelling, pain relieving.For cough and asthma due to lung deficiency;Coronary heart disease, angina pectoris, hyperlipidemia.
The optimum ratio of the Chinese medicine composition of the treatment diabetes of the present invention is: Radix Et Rhizoma Rhei 30 weight portion, Radix Glycyrrhizae Preparata 30 weight Part, Radix Scutellariae 45 weight portion, Radix Rehmanniae Preparata 45 weight portion, Rhizoma Dioscoreae 50 weight portion, Radix Adenophorae (Radix Glehniae) 40 weight portion, Rhizoma Coptidis 45 weight portion, the Rhizoma Anemarrhenae 45 Weight portion, weight portion Radix Ophiopogonis 45, Rhizoma Polygonati 45 weight portion, Fructus Lycii 45 weight portion, Rhizoma Polygonati Odorati 45 weight portion, Rhizoma Atractylodis 45 weight portion, Cortex Phellodendri 45 weight portions, Fructus Schisandrae Chinensis 45 weight portion, Radix Codonopsis 45 weight portion, Radix Puerariae 60 weight portion, Radix Trichosanthis 60 weight portion, Radix Astragali 60 weight Part, Herba Potentillae Discoloris 60 weight portion, fevervine 60 weight portion, Semen Sojae Preparatum 60 weight portion, Hirudo 60 weight portion, Radix Notoginseng 60 weight portion, thorn Slender acanthopanax seed 50 weight portion, Herba Dendrobii 30 weight portion, Ramulus Euonymi 60 weight portion, Herba Apocyni veneti 60 weight portion, Folium Ginkgo 45 weight portion.
The Chinese medicine composition of the present invention can make various preparation as required, such as powder and watered pill.The fineness of powder Generally 80-100 mesh.Watered pill, the particle diameter of every watered pill is generally 2-2.5mm, i.e. Semen phaseoli radiati grain size.Wherein, powder uses The most convenient, more often use.
The using method of the Chinese medicine composition of the treatment diabetes of the present invention is: powder, three times a day, and morning, noon and afternoon taking medicine before meal With, it is grown up each 9 grams, warm water delivery service, 30 days courses for the treatment of;Watered pill, three times a day, the morning, noon and afternoon are bfore meals, are grown up each 30 Grain, warm water delivery service, 30 days courses for the treatment of.
The present invention is according to the preparation method of the Chinese medicine composition of dosage form difference two kinds of above-mentioned treatment diabetes of offer:
One is weighting raw materials by weight ratio, grinds into fine powder, sieves, mixing, the Chinese drug-treated group of the diabetes that obtain medical treatment Compound;
Wherein, grinding to form fine powder, sieve, mixing is all that those skilled in the art commonly use pharmaceutical technology, is not particularly limited, Concrete fineness selects as required, generally 80-100 mesh;
Two is weighting raw materials by weight ratio, adds machine for making water-bindered pills, makes watered pill, the Chinese drug-treated group of the diabetes that obtain medical treatment Compound;
Wherein, machine for making water-bindered pills is prior art, and the slurry that machine for making water-bindered pills uses can be the mixture of starch and water;Machine for making water-bindered pills Rate of charge may is that starch quality, water quality, crude drug gross mass are 5:95:5.
The present invention is further illustrated below in conjunction with embodiment.
Embodiment 1
The Chinese medicine composition for the treatment of diabetes, by Radix Et Rhizoma Rhei 20 weight portion, Radix Glycyrrhizae Preparata 20 weight portion, Radix Scutellariae 35 weight portion, ripe Radix Rehmanniae 35 weight portion, Rhizoma Dioscoreae 40 weight portion, Radix Adenophorae (Radix Glehniae) 30 weight portion, Rhizoma Coptidis 35 weight portion, the Rhizoma Anemarrhenae 35 weight portion, weight Radix Ophiopogonis 35 Part, Rhizoma Polygonati 35 weight portion, Fructus Lycii 35 weight portion, Rhizoma Polygonati Odorati 35 weight portion, Rhizoma Atractylodis 35 weight portion, Cortex Phellodendri 35 weight portion, Fructus Schisandrae Chinensis 35 Weight portion, Radix Codonopsis 35 weight portion, Radix Puerariae 55 weight portion, Radix Trichosanthis 55 weight portion, Radix Astragali 55 weight portion, Herba Potentillae Discoloris 55 weight Part, fevervine 55 weight portion, Semen Sojae Preparatum 55 weight portion, Hirudo 55 weight portion, Radix Notoginseng 55 weight portion, Radix Et Caulis Acanthopanacis Senticosi seed 40 weight portion, Herba Dendrobii 20 weight portion, Ramulus Euonymi 55 weight portion, Herba Apocyni veneti 55 weight portion and Folium Ginkgo 40 weight portion composition.
The preparation method of the Chinese medicine composition of above-mentioned treatment diabetes: weighting raw materials by weight ratio, grinds into fine powder, Cross 80 mesh sieves, mixing, the Chinese medicine composition of the diabetes that obtain medical treatment.
The drug effect of the Chinese medicine composition of embodiment 1 is detected: 400 examples randomly drawed suffer from the patient of diabetes and enter Row clinical trial, wherein male patient 230 example, female patient 170 example, the age be 25-72 year, the course of disease 3 months to 8 years, sick plant For primary diabetes mellitus or secondary diabetes.Method of administration: three times a day, each 9 grams, 30 days be a course for the treatment of.Observe three treatments Journey, result is as shown in table 1.
The drug effect of the Chinese medicine composition of table 1 embodiment 1
Embodiment 2
The Chinese medicine composition for the treatment of diabetes, by Radix Et Rhizoma Rhei 40 weight portion, Radix Glycyrrhizae Preparata 40 weight portion, Radix Scutellariae 55 weight portion, ripe Radix Rehmanniae 55 weight portion, Rhizoma Dioscoreae 60 weight portion, Radix Adenophorae (Radix Glehniae) 50 weight portion, Rhizoma Coptidis 55 weight portion, the Rhizoma Anemarrhenae 55 weight portion, weight Radix Ophiopogonis 55 Part, Rhizoma Polygonati 55 weight portion, Fructus Lycii 55 weight portion, Rhizoma Polygonati Odorati 55 weight portion, Rhizoma Atractylodis 55 weight portion, Cortex Phellodendri 55 weight portion, Fructus Schisandrae Chinensis 55 Weight portion, Radix Codonopsis 55 weight portion, Radix Puerariae 70 weight portion, Radix Trichosanthis 70 weight portion, Radix Astragali 70 weight portion, Herba Potentillae Discoloris 70 weight Part, fevervine 70 weight portion, Semen Sojae Preparatum 70 weight portion, Hirudo 70 weight portion, Radix Notoginseng 70 weight portion, Radix Et Caulis Acanthopanacis Senticosi seed 60 weight portion, Herba Dendrobii 40 weight portion, Ramulus Euonymi 70 weight portion, Herba Apocyni veneti 70 weight portion and Folium Ginkgo 55 weight portion.
The preparation method of the Chinese medicine composition of above-mentioned treatment diabetes: weighting raw materials by weight ratio, grinds into fine powder, Cross 100 mesh sieves, mixing, the Chinese medicine composition of the diabetes that obtain medical treatment.
The drug effect of the Chinese medicine composition of embodiment 2 is detected: 400 examples randomly drawed suffer from the patient of diabetes and enter Row clinical trial, wherein male patient 197 example, female patient 203 example, the age be 30-72 year, the course of disease 3 months to 8 years, sick plant For primary diabetes mellitus or secondary diabetes.Method of administration: three times a day, each 9 grams, 30 days be a course for the treatment of.Observe three treatments Journey, result is as shown in table 2.
The drug effect of the Chinese medicine composition of table 2 embodiment 2
Embodiment 3
The Chinese medicine composition for the treatment of diabetes, by Radix Et Rhizoma Rhei 30 weight portion, Radix Glycyrrhizae Preparata 30 weight portion, Radix Scutellariae 45 weight portion, ripe Radix Rehmanniae 45 weight portion, Rhizoma Dioscoreae 50 weight portion, Radix Adenophorae (Radix Glehniae) 40 weight portion, Rhizoma Coptidis 45 weight portion, the Rhizoma Anemarrhenae 45 weight portion, weight Radix Ophiopogonis 45 Part, Rhizoma Polygonati 45 weight portion, Fructus Lycii 45 weight portion, Rhizoma Polygonati Odorati 45 weight portion, Rhizoma Atractylodis 45 weight portion, Cortex Phellodendri 45 weight portion, Fructus Schisandrae Chinensis 45 Weight portion, Radix Codonopsis 45 weight portion, Radix Puerariae 60 weight portion, Radix Trichosanthis 60 weight portion, Radix Astragali 60 weight portion, Herba Potentillae Discoloris 60 weight Part, fevervine 60 weight portion, Semen Sojae Preparatum 60 weight portion, Hirudo 60 weight portion, Radix Notoginseng 60 weight portion, Radix Et Caulis Acanthopanacis Senticosi seed 50 weight portion, Herba Dendrobii 30 weight portion, Ramulus Euonymi 60 weight portion, Herba Apocyni veneti 60 weight portion and Folium Ginkgo 45 weight portion composition.
The preparation method of the Chinese medicine composition of above-mentioned treatment diabetes: weighting raw materials by weight ratio, grinds into fine powder, Cross 100 mesh sieves, mixing, the Chinese medicine composition of the diabetes that obtain medical treatment.
The drug effect of the Chinese medicine composition of embodiment 3 is detected: 500 examples randomly drawed suffer from the patient of diabetes and enter Row clinical trial, wherein male patient 205 example, female patient 295 example, the age be 27-72 year, the course of disease 2 months to 8 years, sick plant For primary diabetes mellitus or secondary diabetes.Method of administration: three times a day, each 9 grams, 30 days be a course for the treatment of.Observe three treatments Journey, result is as shown in table 3.
The drug effect of the Chinese medicine composition of table 3 embodiment 3
The criterion of therapeutical effect that above-described embodiment 1-3 uses is:
Recovery from illness: clinical symptom disappearance, physical and chemical index is normal, and whole blood blood glucose is below 6.1 i.e. on an empty stomach;
Take a turn for the better: clinical symptoms relatively treats front improvement, and whole blood blood glucose declines on an empty stomach;
Invalid: clinical symptoms is not improved or deteriorated;Whole blood blood glucose is unchanged on an empty stomach or raises.
Cure rate is that recovery from illness number of cases accounts for the percentage ratio of total number of cases, total effective rate be recovery from illness number of cases account for the percentage ratio of total number of cases with Improvement number of cases accounts for the percentage ratio sum of total number of cases, and after the drug withdrawal half a year of rate repeatedly is drug withdrawal half a year, the patient of Relapse rate accounts for total example The percentage ratio of number.
Detecting through embodiment 1-3, the Chinese medicine composition of the present invention has no side effect appearances, continuous observation recovery from illness half a year trouble Person, the state of an illness is difficult to repeatedly;And instant effect, use continuously one month the most effective, all have good treatment to imitate each paradiabetes Really.
Obviously, above-described embodiment is only for clearly demonstrating example, and not restriction to embodiment.Right For those of ordinary skill in the field, can also make on the basis of the above description other multi-form change or Variation.Here without also cannot all of embodiment be given exhaustive.And the obvious change thus extended out or Change among still in the protection domain of the invention.

Claims (8)

1. treat the Chinese medicine composition of diabetes, it is characterised in that composition and weight proportion be: Radix Et Rhizoma Rhei 20-40 weight portion, moxibustion are sweet Grass 20-40 weight portion, Radix Scutellariae 35-55 weight portion, Radix Rehmanniae Preparata 35-55 weight portion, Rhizoma Dioscoreae 40-60 weight portion, Radix Adenophorae (Radix Glehniae) 30-50 weight Part, Rhizoma Coptidis 35-55 weight portion, Rhizoma Anemarrhenae 35-55 weight portion, 35-55 weight portion Radix Ophiopogonis, Rhizoma Polygonati 35-55 weight portion, Fructus Lycii 35-55 Weight portion, Rhizoma Polygonati Odorati 35-55 weight portion, Rhizoma Atractylodis 35-55 weight portion, Cortex Phellodendri 35-55 weight portion, Fructus Schisandrae Chinensis 35-55 weight portion, Radix Codonopsis 35-55 weight portion, Radix Puerariae 55-70 weight portion, Radix Trichosanthis 55-70 weight portion, Radix Astragali 55-70 weight portion, Herba Potentillae Discoloris 55-70 weight Amount part, fevervine 55-70 weight portion, Semen Sojae Preparatum 55-70 weight portion, Hirudo 55-70 weight portion, Radix Notoginseng 55-70 weight portion, thorn five Add seed 40-60 weight portion, Herba Dendrobii 20-40 weight portion, Ramulus Euonymi 55-70 weight portion, Herba Apocyni veneti 55-70 weight portion, Semen Ginkgo Leaf 40-55 weight portion.
The Chinese medicine composition for the treatment of diabetes the most according to claim 1, it is characterised in that described composition and weight proportion For: Radix Et Rhizoma Rhei 30 weight portion, Radix Glycyrrhizae Preparata 30 weight portion, Radix Scutellariae 45 weight portion, Radix Rehmanniae Preparata 45 weight portion, Rhizoma Dioscoreae 50 weight portion, Radix Adenophorae (Radix Glehniae) 40 weight portions, Rhizoma Coptidis 45 weight portion, the Rhizoma Anemarrhenae 45 weight portion, weight portion Radix Ophiopogonis 45, Rhizoma Polygonati 45 weight portion, Fructus Lycii 45 weight portion, jade Bamboo 45 weight portion, Rhizoma Atractylodis 45 weight portion, Cortex Phellodendri 45 weight portion, Fructus Schisandrae Chinensis 45 weight portion, Radix Codonopsis 45 weight portion, Radix Puerariae 60 weight Part, Radix Trichosanthis 60 weight portion, Radix Astragali 60 weight portion, Herba Potentillae Discoloris 60 weight portion, fevervine 60 weight portion, Semen Sojae Preparatum 60 weight Part, Hirudo 60 weight portion, Radix Notoginseng 60 weight portion, Radix Et Caulis Acanthopanacis Senticosi seed 50 weight portion, Herba Dendrobii 30 weight portion, Ramulus Euonymi 60 weight Part, Herba Apocyni veneti 60 weight portion, Folium Ginkgo 45 weight portion.
The Chinese medicine composition for the treatment of diabetes the most according to claim 1, it is characterised in that in described treatment diabetes Drug composition is powder or watered pill.
The Chinese medicine composition for the treatment of diabetes the most according to claim 3, it is characterised in that in described treatment diabetes Drug composition is powder, and fineness is 80-100 mesh.
The Chinese medicine composition for the treatment of diabetes the most according to claim 3, it is characterised in that in described treatment diabetes Drug composition is watered pill, and particle diameter is 2-2.5mm.
6. the preparation method of the Chinese medicine composition of the treatment diabetes described in claim 1-4 any one, it is characterised in that press Weight proportion weighting raw materials, grinds into fine powder, sieves, mixing, the Chinese medicine composition of the diabetes that obtain medical treatment.
7. the preparation method of the Chinese medicine composition of the treatment diabetes described in claim 1-3,5 any one, it is characterised in that Weighting raw materials by weight ratio, adds machine for making water-bindered pills, makes watered pill, the Chinese medicine composition of the diabetes that obtain medical treatment.
The preparation method of the Chinese medicine composition for the treatment of diabetes the most according to claim 7, it is characterised in that the described watered pill The mixture that slurry is starch and water that machine uses;The rate of charge of machine for making water-bindered pills is: the total matter of starch quality, water quality, crude drug Amount is 5:95:5.
CN201610656811.6A 2016-08-11 2016-08-11 Chinese medicine composition for the treatment of diabetes and preparation method thereof Withdrawn CN106177495A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108498708A (en) * 2018-04-18 2018-09-07 致宁医药(肇庆)股份有限公司 A kind of Chinese medicine composition for treating diabetes
CN108524720A (en) * 2018-04-28 2018-09-14 曾发忠 A kind of Chinese medicine composition and preparation method thereof for treating diabetes
TWI721367B (en) * 2018-08-15 2021-03-11 大陸商通化特立杰爾醫藥技術推廣服務有限公司 Composition for regulating endocrine, improving immunity, delaying aging and preventing or treating constipation, its application and preparation method thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108498708A (en) * 2018-04-18 2018-09-07 致宁医药(肇庆)股份有限公司 A kind of Chinese medicine composition for treating diabetes
CN108524720A (en) * 2018-04-28 2018-09-14 曾发忠 A kind of Chinese medicine composition and preparation method thereof for treating diabetes
TWI721367B (en) * 2018-08-15 2021-03-11 大陸商通化特立杰爾醫藥技術推廣服務有限公司 Composition for regulating endocrine, improving immunity, delaying aging and preventing or treating constipation, its application and preparation method thereof

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