CN104173975A - Traditional Chinese medicine composition for treating diabetes mellitus - Google Patents
Traditional Chinese medicine composition for treating diabetes mellitus Download PDFInfo
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- CN104173975A CN104173975A CN201410420337.8A CN201410420337A CN104173975A CN 104173975 A CN104173975 A CN 104173975A CN 201410420337 A CN201410420337 A CN 201410420337A CN 104173975 A CN104173975 A CN 104173975A
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Abstract
The invention provides a traditional Chinese medicine composition for treating diabetes mellitus. The composition is prepared from the following components: lagenaria siceraria, sunflower disc, vinegar soaked black beans, poria cocos, bitter gourd pieces, kudzu vine root, guava, polygonatum kingianum, raw ginger, astragalus membranaceus, radix rehmanniae, cortex lycii radicis, coptis chinensis, cortex mori radicis, galla chinensis, radix scrophulariae, rhizoma anemarrhenae, mulberry, honey-fried licorice root, fructus xanthii and alum, wherein the vinegar soaked black beans are prepared by soaking washed black beans in edible vinegar for 2-3 days. In the composition, a plurality of traditional Chinese medicinal materials with special effect on lowering blood glucose are adopted as monarch drugs, and are compatible with proper auxiliary drugs. The effective components prepared by decocting and extracting serve as a medicinal liquid, and play a role in lowering blood glucose after being taken, so that polyuria, polydipsia, polyphagia, fatigue and other uncomfortable symptoms caused by diabetes mellitus can be quickly relieved, and the diabetes mellitus can be effectively cured.
Description
Technical field
The present invention relates to diagnosis and the treatment field of disease, specifically a kind of Chinese medicine composition that is used for the treatment of diabetes.
Background technology
Diabetes be one group due to the metabolic disease taking hyperglycemia as feature due to defect of insulin secretion and/or insulin action obstacle.Continue hyperglycemia and can cause body tissue's organ, particularly eye, kidney, cardiovascular and neural infringement and dysfunction and exhaustion with long-term metabolism disorder etc.Severe patient can cause acute complications ketoacidosis and the Hyperosmotic comas such as dehydration, electrolyte disturbance and acid base imbalance.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition that is used for the treatment of diabetes, this product belongs to pure Chinese medicinal preparation, take rear without any side effect, the effectively polyuria of reduction of patient, polydipsia, polyphagia and weak phenomenon.
The present invention solves the problems of the technologies described above the technical scheme of employing to be: a kind of Chinese medicine composition that is used for the treatment of diabetes, according to weight ratio, by 11-12 part dish calabash, 5-7 part Receptaculum Helianthi, the vinegar bubble Semen sojae atricolor of 7-9 part, the Poria of 3-5 part, the Fructus Momordicae charantiae slice of 11-13 part, the Radix Puerariae of 7-8 part, the Fructus psidii guajavae immaturus of 8-10 part, 8-9 part Rhizoma Polygonati, the Rhizoma Zingiberis Recens of 3-5 part, the Radix Astragali of 6-7 part, the Radix Rehmanniae of 3-5 part, the Cortex Lycii of 11-13 part, the Rhizoma Coptidis of 9-11 part, the Cortex Mori of 5-7 part, the Galla Chinensis of 3-5 part, the Radix Scrophulariae of 2-3 part, the Rhizoma Anemarrhenae of 4-6 part, the Fructus Mori of 8-10 part, the Radix Glycyrrhizae Preparata of 6-8 part, the Alumen composition of the Fructus Xanthii of 7-9 part and 0.3-0.5 part, described vinegar bubble Semen sojae atricolor is in vinegar, to soak after 2-3 days and obtain after Semen sojae atricolor is cleaned.
In described Chinese medicine composition, also contain Petiolus nelumbinis, the Amylum Nelumbinis Rhizomatis of 2-3 part and the Ootheca Mantidis of 5-7 part of 4-5 part.
The instructions of taking of above-mentioned Chinese medicine composition: proportionally weigh above-mentioned medical material and put in medicinal cupping, put into wherein more appropriate water, after boiling with high heat, use instead after little fiery infusion 30min, filter out medicinal residues wherein, after remaining medicinal liquid is cooling, be divided into three parts, per morning, noon and afternoon one after each meal.
The present invention's each medical material pharmacology and property of medicine used is as follows:
Dish calabash: cold in nature, sweet in the mouth.Have heat clearing away, expelling summer-heat, quenches the thirst, relieving restlessness, effect of diuretic.Suitable various types of edema, such as cardiac edema, oedema due to nephritis, cirrhotic ascites etc. are edible; Suitable summer, dysphoria with smothery sensation was thirsty, or edible in calentura xerostomia;
Receptaculum Helianthi: the floral disc of taking off sunflower seed after Helianthi autumn harvest;
Poria: sweet in the mouth, light, property is flat, GUIXIN warp, lung meridian, spleen channel, kidney channel; Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, has loose bowels, palpitation and restlessness, insomnia forgetfulness, the diseases such as seminal emission nebulousurine;
Fructus Momordicae charantiae slice: fresh Fructus Momordicae charantiae section.Pharmacological experiment proves: Fructus Momordicae charantiae crude extract has the effect of significant reduction blood glucose, measured by radioimmunoassay Fructus Momordicae charantiae extract and Insulin receptor INSR, insulin antibody all have obvious association reaction, show that it and islets of langerhans have common antigenicity and biological activity, Fructus Momordicae charantiae crude extract has the effect of similar insulin;
Radix Puerariae: the flavone extracting in Radix Puerariae can increase brain and crown vascular flow, vascular resistance reduces, and has hypotensive effect, and puerarin can make alloxan diabetes Mus blood glucose obviously decline, and blood sugar reducing function is lasting;
Fructus psidii guajavae immaturus: animal and clinical research show that Folium Psidii Guajavae effective ingredient is flavonoid glycoside, has the combination that promotes single-minded receptor on insulin and target cell membrane, can adjust sugar, lipid metabolism, has blood sugar reducing function, and has certain blood pressure lowering, effect for reducing fat;
Rhizoma Polygonati: Rhizoma Polygonati is used as medicine with rhizome, has boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney benefiting functions, is used for the treatment of weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, the interior-heat disease such as quench one's thirst; There is anti-fatty liver, reduce blood glucose and hypotensive effect, and energy blood fat reducing has the effect of atherosclerosis;
Rhizoma Zingiberis Recens: warm in nature, acrid in the mouth, returns lung, spleen, stomach warp, has effect of relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, for Deficiency and coldness of spleen and stomach, loss of appetite, nausea and vomiting, or vomiting due to fluid-retention, the vomiting of disorder of stomach-QI; Wind and cold or cold-phlegm cough; Cold, fever with aversion to wind, nasal obstruction headache;
The Radix Astragali: sweet in the mouth, slightly warm in nature, returns lung, spleen, liver, kidney channel.The Radix Astragali has effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.The invigorating middle warmer of Radix Astragali Preparata QI invigorating, raw by consolidating superficial resistance holder skin ulcer; Pharmacological research has myocardial contraction, the diastole coronary vasodilator of reinforcement, reduces blood pressure, protects hepatocyte, reduces blood glucose effect;
Radix Rehmanniae: pharmacological research has the effect of the blood glucose of reduction, and can suppress experimental hyperglycemia, and the sugar-lowering components of Radix Rehmanniae is rehmanin;
Cortex Lycii: be the root bark of matrimony vine of solanaceae plant, there is removing heat from blood except effects such as treasure, lung heat clearing pathogenic fire reducing.Cold in nature, sweet in the mouth; There is removing heat from blood to remove steaming, lung heat clearing pathogenic fire reducing function, for deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis; Pharmacological research has obvious blood pressure lowering and reduces blood glucose effect: gavage Cortex Lycii decoct to rabbit, first make the blood glucose short time raise, then reduce lastingly, after 4 ~ 8 hours, not yet recover;
Rhizoma Coptidis: bitter in the mouth, cold in nature, nontoxic.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.There is heat clearing and damp drying, effect of eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, the auditory meatus disease such as suppurate; According to clinical report, the berberine in Rhizoma Coptidis can make blood glucose obviously reduce.Rhizoma Coptidis water decoction can reduce the blood glucose of normal mouse and alloxan diabetes Mus.Experiment shows that the blood sugar lowering mechanism of berberine does not affect secretion and the release of insulin, does not also affect number and the affinity of Hepatocyte Insulin, but by suppressing gluconeogenesis and promoting that glycolysis produces blood sugar reducing function;
Cortex Mori: sweet in the mouth, cold in nature, enters lung meridian.There is eliminating pathogen from the lung for relieving asthma, effect of inducing diuresis to remove edema.For lung-heat cough with asthma, the edema of the face, the diseases such as dysuria.Research is found: compound recipe Cortex Mori concentrated solution large (30g/kg), in (15g/kg) dosage group alloxan induced mice diabetes are had to obvious blood sugar reducing function, glucose hyperglycemia is had to certain blood sugar reducing function;
Galla Chinensis: sour in the mouth, puckery, cold in nature; Return lung, large intestine, kidney channel; Have astringe the lung, effect of hidroschesis, astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs, hemostasis, removing toxic substances, cure mainly chronic cough of deficiency lung, spontaneous sweating, chronic dysentery chronic diarrhea, proctoptosis, seminal emission, nebulousurine, various hemorrhage, carbuncle furuncle;
Radix Scrophulariae: have blood pressure lowering, reduce blood glucose effect, animal experiment shows that Radix Scrophulariae fluid extract can make the blood glucose of normal rabbits decline;
The Rhizoma Anemarrhenae: belong to gunpowder under heat clearing away, property hardship, sweet, cold.Return lung, stomach, kidney channel.Cure mainly: epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, the stranguria with turbid discharge of quenching one's thirst;
Fructus Mori: the fruit that is Moraceae Morus perennial woody plant mulberry.Sweet in the mouth, acid, cold in nature, GUIXIN, liver, kidney channel.The effect that has the YIN nourishing of enriching blood, promotes the production of body fluid and moisturize.For the thirsty interior-heat of the vertigo and tinnitus palpitation and insomnia early whitening of beard and hair Tianjin wound blood deficiency and constipation of quenching one's thirst, the liver and the kidney tonifying taste liquid that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls hepatic and renal YIN deficiency, quench one's thirst, and constipation, the dark tinnitus of order, scrofula, the diseases such as articular instability;
Radix Glycyrrhizae Preparata: Radix Glycyrrhizae Preparata is with the honey Radix Glycyrrhizae of smoking, and is commonly called as the process of preparing Chinese medicine, Mel is put in pot and is smelt middle honey exactly, uses slow fire instead and adds Radix Glycyrrhizae sheet and stir evenly, and 3～5 min take the dish out of the pot, and puts barn or baking oven and is dried to taking-up when tack-free, cools.Sweet in the mouth, property is flat.GUIXIN, lung, spleen, stomach warp.There is spleen reinforcing stomach function regulating, effect of Yiqi and vein recovery;
Fructus Xanthii: bitter in the mouth, sweet, pungent, warm in nature, mild toxicity, enters lung, Liver Channel, controls headche due to wind-cold, nasal sinusitis, toothache, anemofrigid-damp arthralgia, limb pain twin, mange, the diseases such as pruritus; Contained white crystalline glycoside, can make normal rabbits blood glucose decline;
Alumen: claim again potassium aluminium alum, al alum, arcanite, Alumen, raw vitriol, chemistry 12 hydrazine aluminum sulfate potassium by name are that mineral alunite refines the crystallization forming through processing.Return lung, spleen, liver, large intestine channel.There is expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, effect of parasite killing.Control epilepsy, sore throat, remorse saliva is stopped up very, hepatitis, jaundice, general edema with yellowish skin, Stomach duodenum ulcer, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, the diseases such as water, fire, insect bite;
Petiolus nelumbinis: be petiole and the anthocaulus of perennial aquatic herbaceous plant Flos nymphaeae (Nymphaea teragona Georgi), have another name called Rhizoma Nelumbinis bar, seedpod of the lotus bar, Folium Nelumbinis stalk.Feeble QI, lightly seasoned hardship, property is flat, enters spleen, urinary bladder channel.There are expelling summer-heat heat clearing away, regulating QI to expel dampness, ventilation the chest stuffiness relieving, the antiabortive function of stomach function regulating, cure mainly that heat-damp in summer is not uncomfortable in chestly relaxed, had loose bowels, dysentery, gonorrhea, leukorrhagia, vomiting during pregnancy, frequent fetal movement;
Amylum Nelumbinis Rhizomatis: sweet in the mouth, property is flat, cures mainly heat thirsty, scattered silt blood, granulation promoting; Ripe Rhizoma Nelumbinis sweet in the mouth warm in nature, has stomach reinforcing spleen invigorating, a tonification of nourishing blood, diarrhea-relieving function;
Ootheca Mantidis: salty in the mouth, sweet, property is flat.Enter liver, kidney channel, urinary bladder channel, for emission due to deficiency of the kidney, premature ejaculation, sexual impotence, nebulousurine, is with inferior disease.
Beneficial effect: the present invention adopts multiplely has the Chinese crude drug of special effect as monarch drug to blood sugar lowering, and then select suitable accessory drugs to carry out compatibility with it, extract effective ingredient as medicinal liquid through infusion, after taking, play the hypoglycemic effect of falling, polyuria that rapid recovery diabetes are brought, polydipsia, polyphagia and the malaise symptoms such as weak, effectively cure diabetes.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated, and in the present invention, each medical material used all can be buied in pharmacy.
Embodiment 1
A kind of Chinese medicine composition that is used for the treatment of diabetes, according to weight ratio, by 11 parts of dish calabashs, 5 parts of Receptaculum Helianthi, the vinegar bubble Semen sojae atricolor of 7 parts, the Poria of 3 parts, the Fructus Momordicae charantiae slice of 11 parts, the Radix Puerariae of 7 parts, the Fructus psidii guajavae immaturus of 8 parts, 8 parts of Rhizoma Polygonatis, the Rhizoma Zingiberis Recens of 3 parts, the Radix Astragali of 6 parts, the Radix Rehmanniae of 3 parts, the Cortex Lycii of 11 parts, the Rhizoma Coptidis of 9 parts, the Cortex Mori of 5 parts, the Galla Chinensis of 3 parts, the Radix Scrophulariae of 2 parts, the Rhizoma Anemarrhenae of 4 parts, the Fructus Mori of 8 parts, the Radix Glycyrrhizae Preparata of 6 parts, the Alumen composition of the Fructus Xanthii of 7 parts and 0.3 part, described vinegar bubble Semen sojae atricolor is in vinegar, to soak after 2-3 days and obtain after Semen sojae atricolor is cleaned.
In order further to improve drug effect, in the present invention, can also add the Petiolus nelumbinis of 4 parts, the Amylum Nelumbinis Rhizomatis of 2 parts and the Ootheca Mantidis of 5 parts.
Embodiment 2
A kind of Chinese medicine composition that is used for the treatment of diabetes, according to weight ratio, by 12 parts of dish calabashs, 7 parts of Receptaculum Helianthi, the vinegar bubble Semen sojae atricolor of 9 parts, the Poria of 5 parts, the Fructus Momordicae charantiae slice of 13 parts, the Radix Puerariae of 8 parts, the Fructus psidii guajavae immaturus of 10 parts, 9 parts of Rhizoma Polygonatis, the Rhizoma Zingiberis Recens of 5 parts, the Radix Astragali of 7 parts, the Radix Rehmanniae of 5 parts, the Cortex Lycii of 13 parts, the Rhizoma Coptidis of 11 parts, the Cortex Mori of 7 parts, the Galla Chinensis of 5 parts, the Radix Scrophulariae of 3 parts, the Rhizoma Anemarrhenae of 6 parts, the Fructus Mori of 10 parts, the Radix Glycyrrhizae Preparata of 8 parts, the Alumen composition of the Fructus Xanthii of 9 parts and 0.5 part, described vinegar bubble Semen sojae atricolor is in vinegar, to soak after 2-3 days and obtain after Semen sojae atricolor is cleaned.
In order further to improve drug effect, in the present invention, can also add the Petiolus nelumbinis of 5 parts, the Amylum Nelumbinis Rhizomatis of 3 parts and the Ootheca Mantidis of 7 parts.
Embodiment 3
A kind of Chinese medicine composition that is used for the treatment of diabetes, according to weight ratio, by 11.5 parts of dish calabashs, 6 parts of Receptaculum Helianthi, the vinegar bubble Semen sojae atricolor of 8 parts, the Poria of 4 parts, the Fructus Momordicae charantiae slice of 12 parts, the Radix Puerariae of 7.5 parts, the Fructus psidii guajavae immaturus of 9 parts, 8.5 parts of Rhizoma Polygonatis, the Rhizoma Zingiberis Recens of 4 parts, the Radix Astragali of 6.5 parts, the Radix Rehmanniae of 4 parts, the Cortex Lycii of 12 parts, the Rhizoma Coptidis of 10 parts, the Cortex Mori of 6 parts, the Galla Chinensis of 4 parts, the Radix Scrophulariae of 2.5 parts, the Rhizoma Anemarrhenae of 5 parts, the Fructus Mori of 9 parts, the Radix Glycyrrhizae Preparata of 7 parts, the Alumen composition of the Fructus Xanthii of 8 parts and 0.4 part, described vinegar bubble Semen sojae atricolor is in vinegar, to soak after 2-3 days and obtain after Semen sojae atricolor is cleaned.
In order further to improve drug effect, in the present invention, can also add the Petiolus nelumbinis of 4.5 parts, the Amylum Nelumbinis Rhizomatis of 2.5 parts and the Ootheca Mantidis of 6 parts.
Below by several model cases, the effect of product of the present invention is described:
Case 1, river so-and-so, 58 years old, female, found at the beginning of 2010 and suffers from diabetes, obstinate; Start for the end of the year 2011 in my institute medically, while being admitted to hospital, to detect 2 hours blood glucose content be 19.8mmol/L to OGTT; Take this product after one month, it is 15.3mmol/L that OGTT detects 2 hours blood glucose content; Adhere to taking after three months, it is 10.4mmol/L that OGTT detects 2 hours blood glucose content; Continue to take after five months, it is 7.8mmol/L that OGTT detects 2 hours blood glucose content;
Case 2, defend so-and-so, 49 years old, man, started to suffer from diabetes, obstinate for 2009; At the beginning of 2012, start in my institute medically, while being admitted to hospital, to detect 2 hours blood glucose content be 23.5mmol/L to OGTT; Take this product after one month, it is 15.7mmol/L that OGTT detects 2 hours blood glucose content; Adhere to taking after three months, it is 9.8mmol/L that OGTT detects 2 hours blood glucose content; Continue to take after five months, it is 8.0mmol/L that OGTT detects 2 hours blood glucose content;
Case 3, Wang, 53 years old, female, suffered from diabetes, within 2011 10, started in my institute medically, and while being admitted to hospital, to detect 2 hours blood glucose content be 25.9mmol/L to OGTT; Take this product after one month, it is 17.3mmol/L that OGTT detects 2 hours blood glucose content; Adhere to taking after three months, it is 9.8mmol/L that OGTT detects 2 hours blood glucose content; Continue to take after five months, it is 7.9mmol/L that OGTT detects 2 hours blood glucose content;
Case 4, Zhang, 61 years old, man, suffered from diabetes, started in June, 2012 in my institute medically, and while being admitted to hospital, to detect 2 hours blood glucose content be 31.4mmol/L to OGTT; Take this product after one month, it is 19.5mmol/L that OGTT detects 2 hours blood glucose content; Adhere to taking after three months, it is 15.3mmol/L that OGTT detects 2 hours blood glucose content; Continue to take after five months, it is 9.1mmol/L that OGTT detects 2 hours blood glucose content.
Claims (2)
1. one kind is used for the treatment of the Chinese medicine composition of diabetes, it is characterized in that: according to weight ratio, by 11-12 part dish calabash, 5-7 part Receptaculum Helianthi, the vinegar bubble Semen sojae atricolor of 7-9 part, the Poria of 3-5 part, the Fructus Momordicae charantiae slice of 11-13 part, the Radix Puerariae of 7-8 part, the Fructus psidii guajavae immaturus of 8-10 part, 8-9 part Rhizoma Polygonati, the Rhizoma Zingiberis Recens of 3-5 part, the Radix Astragali of 6-7 part, the Radix Rehmanniae of 3-5 part, the Cortex Lycii of 11-13 part, the Rhizoma Coptidis of 9-11 part, the Cortex Mori of 5-7 part, the Galla Chinensis of 3-5 part, the Radix Scrophulariae of 2-3 part, the Rhizoma Anemarrhenae of 4-6 part, the Fructus Mori of 8-10 part, the Radix Glycyrrhizae Preparata of 6-8 part, the Alumen composition of the Fructus Xanthii of 7-9 part and 0.3-0.5 part, described vinegar bubble Semen sojae atricolor is in vinegar, to soak after 2-3 days and obtain after Semen sojae atricolor is cleaned.
2. a kind of Chinese medicine composition that is used for the treatment of diabetes according to claim 1, is characterized in that: the Petiolus nelumbinis, the Amylum Nelumbinis Rhizomatis of 2-3 part and the Ootheca Mantidis of 5-7 part that in described Chinese medicine composition, also contain 4-5 part.
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| CN106389965A (en) * | 2016-11-11 | 2017-02-15 | 郭仕玖 | Traditional Chinese medicine composition for treating diabetes and preparation method thereof |
| CN107252052A (en) * | 2017-05-04 | 2017-10-17 | 杨建国 | It is a kind of to treat health food of diabetes and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106389965A (en) * | 2016-11-11 | 2017-02-15 | 郭仕玖 | Traditional Chinese medicine composition for treating diabetes and preparation method thereof |
| CN107252052A (en) * | 2017-05-04 | 2017-10-17 | 杨建国 | It is a kind of to treat health food of diabetes and preparation method thereof |
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Application publication date: 20141203 |