CN102784305A - Traditional Chinese medicine composition for assisting in decreasing blood sugar and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for assisting in decreasing blood sugar and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for assisting in decreasing blood sugar and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises mulberry leaves, wolfberry fruits, balsam pear, astragalus, dendrobium, Chinese yam, kudzu roots and purslane. Oral traditional Chinese medicine preparations prepared by the traditional Chinese medicine composition are remarkable in effect of assistance in decreasing blood sugar, good in curative effect and wide in applicable people, and has no toxicity and side effects.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to Chinese medicine composition of a kind of auxiliary hyperglycemic and preparation method thereof.
Background technology
Diabetes (diabetes) are to act on that body causes hypoinsulinism, insulin resistant etc. and a series of metabolism disorder syndromes such as the sugar that causes, protein, fat, power and water Xie Zhi by inherited genetic factors, immunologic function disorder, infected by microbes and toxin thereof, free radical toxin, Nervous and Mental Factors or the like various virulence factors; Be main feature clinically with the hyperglycemia; Performance such as polyuria, polydipsia, polyphagia can appear in model case, become thin; I.e. " three-many-one-little " symptom; Diabetes (blood glucose) cause complication in case control bad meeting, cause the depleted pathological changes at positions such as kidney, eye, foot, and can't cure.
Diabetes (Diabetes) are divided the diabetes of IDDM, type 2 diabetes mellitus, gestational diabetes and other specific types.In diabetics, the shared ratio of type 2 diabetes mellitus is about 90%.The traditional Chinese medical science thinks that diabetes have following reason: 1, the plain body deficiency of YIN: cause the reason of the plain body deficiency of YIN to have: 1. congenital defect: " Ling Shu Miraculous Pivot or Divine Axis five becomes a piece of writing " said: " all gentle weak person of the five internal organs is apt to sick diseases due to endogenous heat of ZANG FU organs ".Be meant due to parent fetal cultivation deficiency.2. the day after tomorrow, loss was excessive: like the evil infringement of poison, and the cloudy Tianjin of loss.3. change the source deficiency: as it is impaired to change the internal organs of giving birth to cloudy Tianjin, and cloudy having no way of of essence given birth to, and says like " medical secrets of official quench one's thirst door ": " person of quenching one's thirst, former its starts, and due to this then suffers from a deficiency of the kidney, promptly urinates extremely sweet for every." 4. negative and positive relation imbalance between the internal organs, causing cloudy the damage too much eventually, sun must be contained partially, and Yang Taisheng then causes " disappearing ".2, the 1. long-term sweet and refreshing savoury of surfeit of eating and drinking without temperance, obesity makes the fortune function damage of spleen, and is stagnant in the stomach, the intrinsic heat dryness-transformation, and impairment of YIN consumption Tianjin more makes in the stomach scorchingly, and rapid digestion of food and polyorexia increases the weight of.2. because of fat people's excessive phlegm, the stagnation of phlegm heat-transformation also can be consumed cloudy Tianjin, YIN fluid being insufficient can change again give birth to scorching, scorching again must impairment of YIN.So vicious cycle and diabetes takes place.3, disorder of emotion, depression of liver-QI be not because secular feelings will is relaxed, and stasis is given birth to heat, injuring YIN due to production of dryness; Or, cause liver to lose bar and reach because of rage; Mechanism of qi retardance, it is dry also can to give birth to transconversion into heat, and cloudy Tianjin of the bright lung stomach that can disappear, causes lung dryness of the stomach heat, and thirsty polydipsia takes place, rapid digestion of food and polyorexia.With the passing of time the deficiency of YIN scorching, must cause deficiency of both QI and YIN.Deficiency of YIN affecting YANG and the deficiency of QI and declination of YANG phenomenon occurs, because lung, stomach, kidney three be through the cloudy deficiency of vital energy, the deficiency of both YIN and YANG disease that yang-energy is held back and occurred.4, diseases caused by exogenous pathogenic factor six climate exopathogens, the evil infringement of poison diseases caused by exogenous pathogenic factor six climate exopathogens are invaded diffusing cream (pancreas) in the dryness-fire wind heat poison heresy, take up internal organs, and diabetes also can take place in the dryness-transformation impairment of body fluid.Exogenous triple diabetes is the diseases caused by exogenous pathogenic factor six climate exopathogens, the caused diabetes of the evil infringement of poison.
Folium Mori: sweet, hardship, cold.Return lung, Liver Channel.Function with cure mainly: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.Be used for anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.Main component: 1. sterols: be mainly inokosterone, hydroxy ecdysterone, cupreol one β-glycoside, cupreol.2. flavone and flavonoid glycoside: be mainly globulariacitrin, other has Mulberry glycoside, Isoquercitrin etc.3. alkaloids is mainly gynesin, choline, 4. the polysaccharide polysaccharides of Folium Mori can be with blood glucose in gland fast mountain range.5. other classes mainly contain volatile oil, and several amino acids, vitamin etc.
Fructus Lycii: sweet, flat.Return kidney, Liver Channel.Function with cure mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, impotence and seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.Main component: LBP, betanin, flavin is subordinate in beautiful another name for Sichuan Province, plain A of Fructus Lycii and B etc.
Fructus Momordicae charantiae: hardship, cold.Return lung, stomach, the heart, Liver Channel.Function with cure mainly: clearing summer heat, the detoxifcation that makes eye bright, reducing pressure and sugar, diuresis removing heat from blood, separate that labor clears away heart-fire, the QI invigorating tonifying YANG.Be used for the heatstroke heating, toothache, enteritis, dysentery is had blood in stool; Miliaria is controlled in external, the furuncle furuncle and phyma.Main component: 1. Charantin: be mainly cupreol-β-D-glycoside and 5, the equimolecular mixture of 25-bean steroid dienol-3-glycoside.2. aminoacid: like glutamic acid, alanine, Beta-alanine, phenylalanine, proline, butyrine, citrulline, galacturonic acid, pectin etc.
The Radix Astragali: sweet, tepor.Return lung, spleen channel.Function with cure mainly: tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema promotes the production of body fluid and nourishes blood, the row blood stasis dispelling that stagnates, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, hemiplegia, carbuncle is difficult bursts, and bursts for a long time and does not hold back.Main component: 1. saponins: be mainly Radix Astragali saponin I-VIII etc., Radix Astragali saponin first, astramembrannin.2. flavonoid is mainly flavone, isoflavone, and isoflavan, Lignum pterocarpi indici alkane etc. 3. polysaccharide are mainly glucosan and heteropolysaccharide, like astragalus polysaccharides I, II, III etc.
Herba Dendrobii: sweet, Wen Han.Return stomach, kidney channel.Function with cure mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Be used for calentura Tianjin and hinder, the xerostomia excessive thirst, deficiency of stomach-Yin, lack of appetite is retched, and deficiency-heat is not moved back after being ill, hyperactivity of fire caused by deficiency of YIN, the hectic fever due to YIN-deficiency consumptive fever, poor vision, the muscles and bones flaccidity is soft.Main component: alkaloid: be mainly dendrobine, Herba Dendrobii time alkali, 6-hydroxydendrobine, Herba Dendrobii ether alkali, 6-hydroxyl Herba Dendrobii ether alkali, 4-hydroxyl Herba Dendrobii ether alkali, methine Herba Dendrobii element.
Rhizoma Dioscoreae: sweet, flat.Return spleen, lung, kidney channel.Function with cure mainly: spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Main component: mainly starch-containing, polysaccharide, protein, the aminoacid more than 17 kinds etc., wherein Rhizoma Dioscoreae starch has hypoglycemic effect.
Radix Puerariae: suffering, sweet, cold.Return spleen, stomach, lung meridian.Function with cure mainly: expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst, rash, yang invigorating antidiarrheal, dredge the meridian passage, alcoholic intoxication.Be used for the fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea is had loose bowels, dizziness and headache, apoplectic hemiplegia, obstruction of qi in the chest and cardialgia, damage of the spleen and stomach caused by alcoholism.Main component: 1. flavonoid: be mainly daidzin, daidzein, puerarin, puerarin-7-xyloside.2. starch: content is 19～20% in the fresh Radix Puerariae.The dried root of Radix Puerariae rattan is starch-containing 37%, the root of trilobated leaf vine of Herba Gelsemii Elegantis starch-containing 15～20%.
Herba Portulacae: acid, cold.Return liver, large intestine channel.Function with cure mainly: heat-clearing and toxic substances removing, cooling blood for hemostasis, dysentery relieving.Be used for toxic-heat and blood stasis, be used for the carbuncle furuncle, thirsty rash, erysipelas, snake bite and insect sting is had blood in stool, hemorrhoidal bleeding, metrostaxis.Main component: mainly contain a large amount of norepinephrine and volume potassium salt.Also contain DOPA, dopamine, betanidin, isobetanidin, Radix Betae formula, different Radix Betae glycoside, oxalic acid, malic acid, citric acid, glutamic acid, aspartic acid, alanine and glucose, fructose, sucrose etc.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition of auxiliary hyperglycemic, process by Folium Mori, Fructus Lycii, Fructus Momordicae charantiae, the Radix Astragali, Herba Dendrobii, RHIIZOMA DIOSCOREAE frOm Henan of China, Radix Puerariae and Herba Portulacae.
The Chinese medicine composition of a kind of auxiliary hyperglycemic of the present invention, its raw material weight ratio of processing drug effect is:
Folium Mori 15-25 part, Fructus Lycii 5-15 part, Fructus Momordicae charantiae 15-25 part, Radix Astragali 5-15 part, Herba Dendrobii 2-6 part, RHIIZOMA DIOSCOREAE frOm Henan of China 15-25 part, Radix Puerariae 5-15 part, Herba Portulacae 2-6 part.
The Chinese medicine composition of a kind of auxiliary hyperglycemic of the present invention is characterized in that, the raw material weight ratio of processing drug effect is preferably:
20 parts on Folium Mori, 10 parts of Fructus Lycii, 20 parts in Fructus Momordicae charantiae, 10 parts of the Radixs Astragali, 4 parts of Herba Dendrobiis, 20 parts of RHIIZOMA DIOSCOREAE frOm Henan of China, 10 parts of Radix Puerariaes, 5 parts of Herba Portulacaes.
Another object of the present invention is to provide the method for preparing of the Chinese medicine composition of auxiliary hyperglycemic as stated, it is characterized in that, process: Folium Mori 15-25 part by the pharmacodynamic raw materials of following weight portion; Fructus Lycii 5-15 part, Fructus Momordicae charantiae 15-25 part, Radix Astragali 5-15 part; Herba Dendrobii 2-6 part; RHIIZOMA DIOSCOREAE frOm Henan of China 15-25 part, Radix Puerariae 5-15 part, Herba Portulacae 2-6 part.
The method for preparing of Chinese medicine composition of the present invention is characterized in that, may further comprise the steps:
(1) above-mentioned parts by weight of Chinese traditional medicine material Rhizoma Dioscoreae, Herba Dendrobii are pulverized the back and cross the solarization of 100 orders, medicated powder is subsequent use, and medicinal residues add the Radix Astragali, Folium Mori again; Fructus Lycii, Fructus Momordicae charantiae, Radix Puerariae, Herba Portulacae is dropped in the extraction pot; Add 6-8 times of water gaging, heating refluxes, and extracts 2-3 time; Each 1-2 hour, filter and obtain extracting solution, merge extractive liquid,, stand for standby use;
(2) to be concentrated into relative density be 1.2～1.25 extraction concentrated solution to the heating of the extracting solution after will merging;
(3) mix concentrated solution drying under reduced pressure (the drying under reduced pressure condition is 50 ℃, vacuum 0.10MPa) to moisture below 5%, pulverize, it is subsequent use to cross 80 mesh sieves.
(4) add Rhizoma Dioscoreae, the Herba Dendrobii crush, add adjuvant then behind the mix homogeneously with 85% ethanol system soft material, the granulation of 20 mesh sieves, 14 mesh sieve granulate after 60 ℃ of oven dry.
The method for preparing of Chinese medicine composition of the present invention is characterized in that, comprises following preferred steps:
(1) above-mentioned parts by weight of Chinese traditional medicine material Rhizoma Dioscoreae, Herba Dendrobii are pulverized the back and cross the solarization of 100 orders, medicated powder is subsequent use, and medicinal residues add the Radix Astragali, Folium Mori, Fructus Lycii again; Fructus Momordicae charantiae, Radix Puerariae, Herba Portulacae is dropped in the extraction pot, adds 8 times of water gagings; Heating refluxes, and extracts 2 hours for the first time 2 times; 1.5 hours for the second time, filter and obtain extracting solution, merge extractive liquid,, stand for standby use;
(2) to be concentrated into relative density be 1.2～1.25 extraction concentrated solution to the heating of the extracting solution after will merging;
(3) mix concentrated solution drying under reduced pressure (the drying under reduced pressure condition is 50 ℃, vacuum 0.10MPa) to moisture below 5%, pulverize, it is subsequent use to cross 80 mesh sieves.
(4) add Rhizoma Dioscoreae, the Herba Dendrobii crush, add adjuvant then behind the mix homogeneously with 85% ethanol system soft material, the granulation of 20 mesh sieves, 14 mesh sieve granulate after 60 ℃ of oven dry.
Another object of the present invention is to provide peroral dosage forms such as a kind of tablet of controlling auxiliary hyperglycemic, capsule, granule.
Chinese medicine composition of the present invention has following advantage:
1, the most of medical material of Chinese medicine composition of the present invention is the integration of edible and medicinal herbs kind, no hormone, have no side effect, and taking convenience, effect is remarkable.
2, the property of medicine of Chinese medicine composition of the present invention major part is cool; Few part is for cold; Be aided with warm nature,, also take into account the protection and the coordination of the function of the heart, liver, lung, spleen, kidney simultaneously with the side effect of avoiding the medicine of a cold nature to cause too suddenly; Demonstrated fully Chinese medicine organic conception and advantage, made the more comprehensive and treating both the principal and secondary aspects of a disease of drug effect and function.
3, the peroral dosage forms of being processed by above eight flavor medicines such as granule, the auxiliary hyperglycemic effect is remarkable.
The specific embodiment
Following embodiment is used to further specify the present invention, but does not limit the present invention.
Drug effect embodiment
(1) clinical trial, diagnostic criteria is:
Diabetes, impaired, the IFG diagnostic criteria (unit: mmol/l) of carbohydrate tolerance
| Diagnosis | Condition | Blood glucose |
| Diabetes | On an empty stomach | ≥7.0 |
| 2 hours after the meal | ≥11.1 | |
| Carbohydrate tolerance is impaired | On an empty stomach | ＜7.0 |
| 2 hours after the meal | 7.8～11.1 | |
| IFG | On an empty stomach | 6.1～7.0 |
| 2 hours after the meal | ＜7.8 |
Produce effects: 20% before fasting glucose and 2 hours after the meal blood glucose drop to and normal range or fasting glucose and 2 hours after the meal blood glucose descends above treat after testing
Effectively: fasting glucose and 2 hours after the meal blood glucose descend and surpass 10% before the treatment but do not reach the produce effects standard
Invalid: fasting glucose and 2 hours after the meal blood glucose do not descend or descend and do not reach effective standard
Totally 60 of the patients at different sexes, age, one group of 30 people are divided into 2 groups, one group with the treatment of the capsule of embodiment 2 as experimental group, another group with the KELENING capsule as matched group,
The experimental group result is following:
Matched group
The result shows: experimental group and matched group all have the auxiliary hyperglycemic effect; And experimental group effective percentage 93%, matched group 87%, but there was no significant difference, P＞0.05.
(2) case is for example:
Land XX, the man, 60 years old, 10 years medical histories before the treatment, had hunger sensation before the meal, food is many, blurred vision, fasting glucose 8.0, after the meal 11.5 take the capsule of embodiment 2 after, 4 week back hunger sensation disappear, fasting glucose drops to 6.9, post-prandial glycemia drops to 9.2.
Guo XX, the woman, 52 years old, 6 years medical histories before the treatment, had slight hunger sensation before the meal, lassitude, fasting glucose 7.5, after the meal 10.2, take the capsule of embodiment 2 after, 4 week the back hunger sensation disappear, fasting glucose drops to 6.6, post-prandial glycemia drops to 8.6.
Preparation embodiment
Embodiment 1
Folium Mori 20g, Fructus Lycii 10g, Fructus Momordicae charantiae 20g, Radix Astragali 10g, Herba Dendrobii 4g, RHIIZOMA DIOSCOREAE frOm Henan of China 20g; Radix Puerariae 10g, Herba Portulacae 5g pulverizes the back with above-mentioned parts by weight of Chinese traditional medicine material Rhizoma Dioscoreae, Herba Dendrobii and crosses the solarization of 100 orders, and medicated powder is subsequent use, and medicinal residues add the Radix Astragali, Folium Mori again; Fructus Lycii, Fructus Momordicae charantiae, Radix Puerariae, Herba Portulacae is dropped in the extraction pot, adds 6-8 times of water gaging, heating; Reflux, extract 2-3 time, each 1-2 hour, filter and obtain extracting solution, merge extractive liquid,, stand for standby use; It is 1.2～1.25 extraction concentrated solution that the heating of extracting solution after merging is concentrated into relative density; Mix concentrated solution drying under reduced pressure (the drying under reduced pressure condition is 50 ℃, vacuum 0.10MPa) to moisture below 5%, pulverize, it is subsequent use to cross 80 mesh sieves.Add Rhizoma Dioscoreae, the Herba Dendrobii crush, add dextrin then behind the mix homogeneously with 85% ethanol system soft material, the granulation of 20 mesh sieves, 14 mesh sieve granulate after 60 ℃ of oven dry.Be pressed into the tablet of certain specification with tablet machine.
Embodiment 2
Folium Mori 2000g, Fructus Lycii 1000g, Fructus Momordicae charantiae 2000g, Radix Astragali 1000g, Herba Dendrobii 400g, RHIIZOMA DIOSCOREAE frOm Henan of China 2000g; Radix Puerariae 1000g, Herba Portulacae 500g pulverizes the back with above-mentioned parts by weight of Chinese traditional medicine material Rhizoma Dioscoreae, Herba Dendrobii and crosses the solarization of 100 orders, and medicated powder is subsequent use, and medicinal residues add the Radix Astragali, Folium Mori again; Fructus Lycii, Fructus Momordicae charantiae, Radix Puerariae, Herba Portulacae is dropped in the extraction pot, adds 8 times of water gagings, heating; Reflux, extract 2 times, each 2 hours, filter and obtain extracting solution, merge extractive liquid,, stand for standby use; It is 1.2～1.25 extraction concentrated solution that the heating of extracting solution after merging is concentrated into relative density; Mix concentrated solution drying under reduced pressure (the drying under reduced pressure condition is 50 ℃, vacuum 0.10MPa) to moisture below 5%, pulverize, it is subsequent use to cross 80 mesh sieves.Add Rhizoma Dioscoreae, the Herba Dendrobii crush, add dextrin then behind the mix homogeneously with 85% ethanol system soft material, 20 mesh sieves are granulated, after 60 ℃ of oven dry 14 and sieve granulate.Incapsulate, get capsule.
Embodiment 3
Folium Mori 400g, Fructus Lycii 200g, Fructus Momordicae charantiae 400g, Radix Astragali 200g, Herba Dendrobii 80g, RHIIZOMA DIOSCOREAE frOm Henan of China 400g; Radix Puerariae 200g, Herba Portulacae 100g pulverizes the back with above-mentioned parts by weight of Chinese traditional medicine material Rhizoma Dioscoreae, Herba Dendrobii and crosses the solarization of 100 orders, and medicated powder is subsequent use, and medicinal residues add the Radix Astragali, Folium Mori again; Fructus Lycii, Fructus Momordicae charantiae, Radix Puerariae, Herba Portulacae is dropped in the extraction pot, adds 6 times of water gagings, heating; Reflux, extract 2 times, each 2 hours, filter and obtain extracting solution, merge extractive liquid,, stand for standby use; It is 1.2～1.25 extraction concentrated solution that the heating of extracting solution after merging is concentrated into relative density; Mix concentrated solution drying under reduced pressure (the drying under reduced pressure condition is 50 ℃, vacuum 0.10MPa) to moisture below 5%, pulverize, it is subsequent use to cross 80 mesh sieves.Add Rhizoma Dioscoreae, the Herba Dendrobii crush, add dextrin then behind the mix homogeneously with 85% ethanol system soft material, the granulation of 20 mesh sieves, 14 mesh sieve granulate after 60 ℃ of oven dry.Get granule.
Claims (5)
1. the Chinese medicine composition of an auxiliary hyperglycemic is characterized in that, is processed by Folium Mori, Fructus Lycii, Fructus Momordicae charantiae, the Radix Astragali, Herba Dendrobii, RHIIZOMA DIOSCOREAE frOm Henan of China, Radix Puerariae and Herba Portulacae.
2. the Chinese medicine composition of auxiliary hyperglycemic as claimed in claim 1 is characterized in that, is processed by following parts by weight of Chinese traditional medicine: Folium Mori 15-25 part, Fructus Lycii 5-15 part; Fructus Momordicae charantiae 15-25 part, Radix Astragali 5-15 part, Herba Dendrobii 2-6 part; RHIIZOMA DIOSCOREAE frOm Henan of China 15-25 part, Radix Puerariae 5-15 part, Herba Portulacae 2-6 part.
3. like the Chinese medicine composition of the arbitrary described auxiliary hyperglycemic of claim 1-2, it is characterized in that, process: 20 parts on Folium Mori, 10 parts of Fructus Lycii by following parts by weight of Chinese traditional medicine; 20 parts in Fructus Momordicae charantiae, 10 parts of the Radixs Astragali, 4 parts of Herba Dendrobiis; 20 parts of RHIIZOMA DIOSCOREAE frOm Henan of China, 10 parts of Radix Puerariaes, 5 parts of Herba Portulacaes.
4. like the method for preparing of the arbitrary Chinese medicine composition of claim 1-3, it is characterized in that, may further comprise the steps:
(1) above-mentioned parts by weight of Chinese traditional medicine material Rhizoma Dioscoreae, Herba Dendrobii are pulverized the back and cross the solarization of 100 orders, medicated powder is subsequent use, and medicinal residues add the Radix Astragali, Folium Mori again; Fructus Lycii, Fructus Momordicae charantiae, Radix Puerariae, Herba Portulacae is dropped in the extraction pot; Add 6-8 times of water gaging, heating refluxes, and extracts 2-3 time; Each 1-2 hour, filter and obtain extracting solution, merge extractive liquid,, stand for standby use;
(2) to be concentrated into relative density be 1.2～1.25 extraction concentrated solution to the heating of the extracting solution after will merging;
(3) mix concentrated solution drying under reduced pressure (the drying under reduced pressure condition is 50 ℃, vacuum 0.10MPa) to moisture below 5%, pulverize, it is subsequent use to cross 80 mesh sieves.
(4) add Rhizoma Dioscoreae, the Herba Dendrobii crush, add adjuvant then behind the mix homogeneously with 85% ethanol system soft material, the granulation of 20 mesh sieves, 14 mesh sieve granulate after 60 ℃ of oven dry.
5. like the Chinese medicine composition of the arbitrary described auxiliary hyperglycemic of claim 1-3, it is characterized in that: the dosage form of described Chinese medicine composition is tablet, capsule, granule.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106722918A (en) * | 2015-11-25 | 2017-05-31 | 北京华昱安然医药科技有限公司 | A kind of hypoglycemia healthcare food and preparation method thereof |
| CN108310278A (en) * | 2018-04-01 | 2018-07-24 | 张奉明 | A kind of dendrobium candidum composition and preparation method thereof of beneficial blood glucose health |
| CN110179117A (en) * | 2019-07-15 | 2019-08-30 | 青岛瑞思德生物科技有限公司 | A kind of hypoglycemic particle electuary and preparation method thereof |
| CN110368452A (en) * | 2019-06-30 | 2019-10-25 | 杨顺平 | Dendrobium kudzu beans |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104623380B (en) * | 2015-02-26 | 2019-01-01 | 田江南 | A kind of medicine and preparation method thereof for treating diabetes |
| CN105410623B (en) * | 2015-11-30 | 2019-03-19 | 河北康平健康产业有限责任公司 | A kind of reinforcing buckwheat fast food paste and preparation method thereof |
| CN109481571A (en) * | 2018-12-19 | 2019-03-19 | 湖南希尔天然药业有限公司 | A kind of mulberry leaf preparation and preparation method thereof |
| CN110314196A (en) * | 2019-08-17 | 2019-10-11 | 哈尔滨工业大学 | A kind of preparation method of mulberry leaf compound hypoglycemic instant |
| CN113332395B (en) * | 2021-07-28 | 2022-08-26 | 吉林医药学院 | Traditional Chinese medicine composition for treating type 2 diabetes and preparation method thereof |
-
2012
- 2012-03-20 CN CN2012100737023A patent/CN102579839A/en active Pending
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Non-Patent Citations (1)
| Title |
|---|
| 屠庆祝等: "浅谈中药治疗糖尿病的用药规律", 《中医药临床杂志》, no. 03, 28 June 2005 (2005-06-28) * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106722918A (en) * | 2015-11-25 | 2017-05-31 | 北京华昱安然医药科技有限公司 | A kind of hypoglycemia healthcare food and preparation method thereof |
| CN108310278A (en) * | 2018-04-01 | 2018-07-24 | 张奉明 | A kind of dendrobium candidum composition and preparation method thereof of beneficial blood glucose health |
| CN110368452A (en) * | 2019-06-30 | 2019-10-25 | 杨顺平 | Dendrobium kudzu beans |
| CN110179117A (en) * | 2019-07-15 | 2019-08-30 | 青岛瑞思德生物科技有限公司 | A kind of hypoglycemic particle electuary and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN102579839A (en) | 2012-07-18 |
| CN102784305B (en) | 2015-09-30 |
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