Summary of the invention
The invention provides a kind of oral liquid for nursing diabetics and preparation method, for pure Chinese medicinal preparation, selected medical material compatibility is suitable for, and adopts modern advanced medical pharmaceutical technology and make, oral liquid of the present invention has the liver and the kidney tonifying, heat-clearing and toxic substances removing, dehumidifying diuresis, effect of blood circulation and channel invigorating, conditioner body immunity function is carried out by regulating the function of each organ of whole body, to maintain the metabolism of human normal, can effectively treat all kinds diabetes, and suppress to recur more afterwards.
For achieving the above object, being implemented as follows of technical scheme of the present invention:
For nursing an oral liquid for diabetics, raw material composition and the weight of making described oral liquid effective ingredient are:
Caulis Akebiae 50-90g Herba Glechomae 55-85g Fructus Gardeniae 55-85g Rhizoma seu herba Asystasiellae Chinensis 50-85g
Herba Dichodrae 50-80g Herba Hyperici Sampsonii 45-80g Cyclocarya paliurus Iljinskaja 50-75g Mesona chinensis Benth 45-75g
Spora Lygodii 40-70g Pollen Typhae 40-65g Folium Mori 40-70g HANXIAOHUA 30-60g
Semen althaeae roseae 20-55g Herba Plantaginis 25-50g Herba Rostellulariae 20-40g pomelo skin 20-45g.
Raw material composition and the weight of making described oral liquid effective ingredient are:
Caulis Akebiae 80g Herba Glechomae 80g Fructus Gardeniae 80g Rhizoma seu herba Asystasiellae Chinensis 75g
Herba Dichodrae 75g Herba Hyperici Sampsonii 75g Cyclocarya paliurus Iljinskaja 70g Mesona chinensis Benth 70g
Spora Lygodii 60g Pollen Typhae 60g Folium Mori 60g HANXIAOHUA 55g
Semen althaeae roseae 45g Herba Plantaginis 45g Herba Rostellulariae 35g pomelo skin 40g.
Raw material composition and the weight of making described oral liquid effective ingredient are:
Caulis Akebiae 70g Herba Glechomae 75g Fructus Gardeniae 75g Rhizoma seu herba Asystasiellae Chinensis 65g
Herba Dichodrae 65g Herba Hyperici Sampsonii 65g Cyclocarya paliurus Iljinskaja 65g Mesona chinensis Benth 65g
Spora Lygodii 50g Pollen Typhae 55g Folium Mori 55g HANXIAOHUA 45g
Semen althaeae roseae 35g Herba Plantaginis 35g Herba Rostellulariae 30g pomelo skin 35g.
Raw material composition and the weight of making described oral liquid effective ingredient are:
Caulis Akebiae 60g Herba Glechomae 65g Fructus Gardeniae 65g Rhizoma seu herba Asystasiellae Chinensis 55g
Herba Dichodrae 55g Herba Hyperici Sampsonii 55g Cyclocarya paliurus Iljinskaja 55g Mesona chinensis Benth 48g
Spora Lygodii 45g Pollen Typhae 50g Folium Mori 45g HANXIAOHUA 35g
Semen althaeae roseae 25g Herba Plantaginis 30g Herba Rostellulariae 25g pomelo skin 25g.
For nursing a preparation method for the oral liquid of diabetics, comprise following processing step:
(1) Caulis Akebiae, Fructus Gardeniae, Rhizoma seu herba Asystasiellae Chinensis, Herba Dichodrae, Herba Hyperici Sampsonii, Cyclocarya paliurus Iljinskaja, Folium Mori, HANXIAOHUA, Semen althaeae roseae, Herba Plantaginis and Herba Rostellulariae are put into container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion 4-5 hour first, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1 ~ 2 hour, extracts; Merge extractive liquid, filters, obtains filtrate for subsequent use;
(2) Mesona chinensis Benth, Herba Glechomae chopping are mashed, taking juice is for subsequent use;
(3) get Spora Lygodii, Pollen Typhae, the oven dry of pomelo's skin, grind into powder, cross 120 order fine powders, for subsequent use;
(4) by filtrate made for above-mentioned steps (1)-(3), juice and fine powder mixing, utilize modern advanced pharmacy science and technology, making oral liquid, being the described oral liquid for nursing diabetics.
The property of medicine of the present invention's Chinese medicine used is as follows:
Caulis Akebiae: bitter in the mouth, cold in nature, GUIXIN, spleen, kidney, small intestinal, urinary bladder channel; Clearing away heat and promoting diuresis; Blood circulation and channel invigorating.Cure mainly red urine red, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, larynx larynx pain, aphtha of the mouth and tongue, rheumatic arthralgia, galactostasis, amenorrhea, dysmenorrhea.
Herba Glechomae: cold nature, acrid in the mouth, micro-hardship; Return liver, kidney, urinary bladder channel.Heat-clearing and toxic substances removing, diuresis and expelling stone, dissipating blood stasis for subsidence of swelling.For lithangiuria, liver and bile stone, jaundice due to damp-heat, injury from falling down.
Fructus Gardeniae: bitter in the mouth, cold in nature; GUIXIN, lung, tri-jiao channel.Pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.Eliminating fire and detoxication, clearing away heat-damp and promoting diuresis, cool the blood dissipate blood stasis.For infectious hepatitis, traumatic injury, acute toothache.
Rhizoma seu herba Asystasiellae Chinensis: lightly seasoned, cool in nature, return lung meridian; Inducing diuresis to remove edema, heat-clearing and toxic substances removing, dissipating blood stasis stops blooding.For pulmonary tuberculosis, laryngopharynx swelling and pain, diabetes, ascites, traumatic hemorrhage is controlled in external, sprains, furuncle and phyma.
Herba Dichodrae: acrid in the mouth, property is put down; Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.For hepatitis, cholecystitis, dysentery, oedema due to nephritis, urinary system infection, urinary system calculus, tonsillitis, traumatic injury.
Herba Hyperici Sampsonii: acrid in the mouth, hardship, cold in nature.Heat-clearing and toxic substances removing, dredge the meridian passage, cooling blood for hemostasis.For infantile hyperpyrexia, dysentery, enteritis, spits blood, epistaxis, menoxenia, leucorrhea; Traumatic hemorrhage is controlled in external, traumatic injury, mastitis, burn and scald, venom.
Cyclocarya paliurus Iljinskaja: there is many effects such as blood sugar lowering, blood fat reducing, blood pressure lowering, raising immunity.Modern medicine study confirms, cyclocarya paliurus tea is rich in the Organic nutrient such as abundant saponin, flavone, polysaccharide, can active balance human body carbohydrate metabolism, effective reduction triglyceride and cholesterol, there is the function of magical natural blood pressure lowering, blood sugar lowering, blood fat reducing, to enhancing body immunity, antioxidation, defying age, hepatoprotective etc., there is unique effect simultaneously, especially to diabetic population, have remarkable hypoglycemic effect.
Mesona chinensis Benth: there is clearing away summer-heat, the function of antipyretic diuretic.Cure mainly heatstroke, pyretic toxicity, quench one's thirst, hypertension, nephropathy, diabetes, pain of joint muscle, gonorrhea etc.Modern medicine study confirms, in Mesona chinensis Benth's ingredient, Flavonoid substances has the effect suppressing cancer cell growth, reduce blood pressure; Polysaccharide has enhancing and improves human body immune function effect; Essence have calmness, refrigerant, removing toxic substances, diuretic effect; Trace element has the formation of suppression free radical, defying age, anticancer effect; Vitamin can regulate and strengthen physiological function etc.
Spora Lygodii: cold in nature, sweet in the mouth; Return bladder, small intestine meridian; There is eliminating damp-heat, effect for the treatment of stranguria pain relieving.For pyretic stranguria, sand Stranguria, stranguria with blood, stranguria marked by chyluria, Urethra astringent pain, heat-clearing and toxic substances removing, relieving stranguria by diuresis.Control urinary tract infection, lithangiuria, nebulousurine, leucorrhea, hepatitis, oedema due to nephritis, laryngopharynx swelling and pain, mumps, enteritis, dysentery, skin eczema, herpes zoster." Jiangxi medical herbs " carries, " heat-clearing and toxic substances removing, promoting urination to remove dampness.Treating the liver is scorching, renal edema, skin eczema, chickenpox, hematuria.Mumps, acute toothache, throat moth, diphtheria, herpes zoster, children's L infantile malnutrition ".
Pollen Typhae: sweet in the mouth, property is put down, and returns liver, pericardium channel.Hemostasis, blood stasis dispelling, treating stranguria.For spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, blood strangury and dry pain." Bencao Jingshu " carries, and “ Zhi Disorder ties, and five kinds of strain and seven kinds of impairment, stops long-pending blood stasis, and namely front pain is sent out and told nosebleed ".
Folium Mori: bitter in the mouth, sweet, cold in nature, enter liver, lung two warp.Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing the hyperactive liver improving eyesight, cooling blood for hemostasis.Japan's ancient book " eating tea health preserving note " carries, " effect that Folium Mori are improved ' drinking-water is sick ' (i.e. the diabetes of modern medicine) ".Studying data at home and abroad confirms, the alkaloid in Folium Mori and polysaccharide are main blood sugar reducing components.
HANXIAOHUA: acrid in the mouth, hardship, warm in nature, return Liver Channel; Removing pathogenic heat from blood and toxic substance from the body.Modern medicine study confirms, HANXIAOHUA has diuresis composition, can promote the discharge of vivotoxin, improves metabolic efficiency.
Semen althaeae roseae: sweet, cold.Relieving stranguria by diuresis, laxation, expedites the emergence of.For edema, stranguria, constipation and anuresis.Cure mainly edema, nephritis.
herba Plantaginis: sweet in the mouth, light, cold nature; Return lung, liver, kidney, urinary bladder channel." property of medicine is fallen " carries, " can remove pathogenic wind toxic, the liver affected by pathogenic wind heat, malicious wind dotting punch order, swelling pain is hidden from view, and headache lacrimation, removes irritable feverish sensation of chest and heart ".Modern medicine study confirms, Herba Plantaginis has clearing away heat and promoting diuresis, removing heat from blood, the effect of removing toxic substances.
Herba Rostellulariae: salty in the mouth, cold in nature.Return lung, liver, kidney channel.Heat-clearing and toxic substances removing, inducing diuresis to remove edema, invigorates blood circulation.Modern doctor's research confirms, Herba Rostellulariae medicinal liquid has stronger inhibitory action to staphylococcus aureus, congratulates, this is close, Fu Shi, bacterium sonnei also have certain inhibitory action to will.
Pomelo's skin: acrid in the mouth, hardship, sweet, warm in nature, nontoxic.Enter spleen, kidney, bladder three warp.Reduce phlegm, help digestion, the therapeutic method to keep the adverse QI flowing downwards, fast diaphragm.Control the stagnation of QI uncomfortable in chest, coldness and pain in the epigastrium, dyspepsia, cough with asthma, hernia." Traditional Chinese Medicine in Sichuan will " carries, and " alcoholic intoxication, controls kidney edema, and dyspepsia is stagnated, damp-phlegm cough with dyspnea and hernia.”
The present invention compared with prior art, has following beneficial effect:
Oral liquid of the present invention is pure Chinese medicinal preparation, selected medical material compatibility is suitable for, and adopt modern advanced medical pharmaceutical technology to be prepared from, there is the liver and the kidney tonifying, heat-clearing and toxic substances removing, dehumidifying diuresis, effect of blood circulation and channel invigorating, carrys out conditioner body immunity function, to maintain the metabolism of human normal by regulating the function of each organ of whole body, can effectively treat all kinds diabetes, and suppress to recur more afterwards.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Caulis Akebiae 85g Herba Glechomae 83g Fructus Gardeniae 83g Rhizoma seu herba Asystasiellae Chinensis 80g
Herba Dichodrae 78g Herba Hyperici Sampsonii 78g Cyclocarya paliurus Iljinskaja 73g Mesona chinensis Benth 73g
Spora Lygodii 68g Pollen Typhae 63g Folium Mori 65g HANXIAOHUA 58g
Semen althaeae roseae 50g Herba Plantaginis 48g Herba Rostellulariae 38g pomelo skin 42g.
For nursing a preparation method for the oral liquid of diabetics, comprise following processing step:
(1) Caulis Akebiae, Fructus Gardeniae, Rhizoma seu herba Asystasiellae Chinensis, Herba Dichodrae, Herba Hyperici Sampsonii, Cyclocarya paliurus Iljinskaja, Folium Mori, HANXIAOHUA, Semen althaeae roseae, Herba Plantaginis and Herba Rostellulariae are put into container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion 4-5 hour first, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1 ~ 2 hour, extracts; Merge extractive liquid, filters, obtains filtrate for subsequent use;
(2) Mesona chinensis Benth, Herba Glechomae chopping are mashed, taking juice is for subsequent use;
(3) get Spora Lygodii, Pollen Typhae, the oven dry of pomelo's skin, grind into powder, cross 120 order fine powders, for subsequent use;
(4) by filtrate made for above-mentioned steps (1)-(3), juice and fine powder mixing, utilize the modern pharmacy of advanced 5 science and technology, making oral liquid, being the described oral liquid for nursing diabetics.
Usage and dosage: oral, half an hour ante cibum takes, each 15ml, every day three times, and within 15 days, be a course for the treatment of, six to eight courses for the treatment of can cure.
Embodiment 2
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Caulis Akebiae 80g Herba Glechomae 80g Fructus Gardeniae 80g Rhizoma seu herba Asystasiellae Chinensis 75g
Herba Dichodrae 75g Herba Hyperici Sampsonii 75g Cyclocarya paliurus Iljinskaja 70g Mesona chinensis Benth 70g
Spora Lygodii 60g Pollen Typhae 60g Folium Mori 60g HANXIAOHUA 55g
Semen althaeae roseae 45g Herba Plantaginis 45g Herba Rostellulariae 35g pomelo skin 40g.
The oral liquor processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Caulis Akebiae 70g Herba Glechomae 75g Fructus Gardeniae 75g Rhizoma seu herba Asystasiellae Chinensis 65g
Herba Dichodrae 65g Herba Hyperici Sampsonii 65g Cyclocarya paliurus Iljinskaja 65g Mesona chinensis Benth 65g
Spora Lygodii 50g Pollen Typhae 55g Folium Mori 55g HANXIAOHUA 45g
Semen althaeae roseae 35g Herba Plantaginis 35g Herba Rostellulariae 30g pomelo skin 35g.
The oral liquor processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of oral liquid effective ingredient of the present invention and weight are:
Caulis Akebiae 60g Herba Glechomae 65g Fructus Gardeniae 65g Rhizoma seu herba Asystasiellae Chinensis 55g
Herba Dichodrae 55g Herba Hyperici Sampsonii 55g Cyclocarya paliurus Iljinskaja 55g Mesona chinensis Benth 48g
Spora Lygodii 45g Pollen Typhae 50g Folium Mori 45g HANXIAOHUA 35g
Semen althaeae roseae 25g Herba Plantaginis 30g Herba Rostellulariae 25g pomelo skin 25g.
The oral liquor processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection
As the oral liquid for nursing diabetics, select the routine clinical observation of diabetics 245, patient 6 is divided into two groups at random, treatment group 127 example, wherein male 70 example, women 57 example, 38 ~ 60 years old age, 55.4 years old mean age, the course of disease 1 ~ 18 year, average 10.6 years; Severity extent: slight 17 examples, moderate 61 example, severe 47 example.Matched group 118 example, wherein male 65 example, women 53 example, 38 ~ 60 years old age, 53.8 years old mean age, the course of disease 1 ~ 18 year, average 9.7 years; Severity extent: slight 15 examples, moderate 53 example, severe 50 example.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.Keep on a diet all on request for two groups.
2, treatment group patient takes oral liquid of the present invention, each 15ml, every day three times, and within 15 days, be a course for the treatment of, six to eight courses for the treatment of can cure.The oral SHENQI JIANGTANG sheet of matched group, oral 3 times of every day, early, middle and late 30 minutes before the meal oral, within 30 days, is a course for the treatment of, usually needs five to six courses for the treatment of.
3, efficacy determination:
(1) cure: more than 2/3 transference cure after treatment, fasting glucose is down to < 7.2mmol/L, after the meal 2 hours blood glucose < 8.3 mmol/L, twenty-four-hour urine sugar < 10 grams; Or blood glucose, glucose in urine comparatively treat before decline more than 30%.
(2) take a turn for the better: after treatment, 2/3 ~ 1/3 symptom is improved, and fasting glucose is down to < 8.2mmol/L, after the meal 2 hours blood glucose < 10mmol/L, twenty-four-hour urine sugar 10 ~ 25 grams; Or blood glucose, glucose in urine comparatively treat before decline 10 ~ 29%.
(3) invalid: through 6 course of therapy, blood glucose, glucose in urine decline and do not reach effective standard.
4, result
Take in the treatment group of oral liquid of the present invention, cure 84 examples, take a turn for the better 34 examples, no effect 9, total effective rate 92.9%.
Cure 37 examples in matched group, take a turn for the better 45 examples, invalid 36 examples, total effective rate 69.5%.
Above result display, the total effective rate for the treatment of group is apparently higher than matched group.
Oral liquid of the present invention is pure Chinese medicinal preparation, selected medical material compatibility is suitable for, and adopt modern advanced medical pharmaceutical technology to be prepared from, there is the liver and the kidney tonifying, heat-clearing and toxic substances removing, dehumidifying diuresis, effect of blood circulation and channel invigorating, carrys out conditioner body immunity function, to maintain the metabolism of human normal by regulating the function of each organ of whole body, can effectively treat all kinds diabetes, and suppress to recur more afterwards.
Model case is illustrated:
1, Lee: man, 36 years old, Enterprise Staff, people from From Shijiazhuang City of Hebei Province, suffers from diabetes 2 years, feels run-down, build is become thin, and within one day, will eat five meals, can eat but not fat, xerosis cutis, pain in the low back and legs, is hard and dry, to our hospital upon somebody's introduction, disappear in clinical diagnosis is, take oral liquid of the present invention 2 months all diseases and eliminate, body weight increases, and can normally work.
2, revive certain, man, 67 years old, retired cadre, people from Lianyungang, Jiangsu Province, introduce to our hospital through friend, clinical diagnosis is that diabetic condition control is bad, frequent appearance diarrhoea, at ordinary times every day defecation 5 ~ 7 times, every day stage of attack defecation 12 ~ 18 times, stool in the pasty state or watery stool, fecal incontinence time serious, recurrent exerbation, find white and greasy fur on inspection, deep pulse is unable, complexion is not changed, quenching one's thirst property intestinal is diagnosed as sick through the present inventor, the cause of disease is deficiency-weakness of spleen-QI, visceral dysfunction, general diarrhea therapeutic effect is not good, reason is that diabetes cause, metabolism obstacles of blood glucose is main generalized metabolic disorder, take oral liquid of the present invention after 60 days, all diseases alleviate, spirit is doubly good, follow-up investigation, the state of an illness is without recurrence.
3, Liu, female, 52 years old, people from Guangzhou, Guangdong, introduces to our hospital through friend, over readme more than ten years of morbidity; frequently, quantity is many, will get up in the night to urinate every night 7,8 times; urinate pleasantly sweet; with hypertension, coronary heart disease, once arrives too much family hospital therapy for urine, but unsatisfactory curative effect; and take oral liquid of the present invention after 3 months, above-mentioned symptom subtracts most.