CN112076305A - A Chinese medicinal oral and topical stock solution mixture for treating metabolic syndrome and resisting bacteria and inflammation - Google Patents

A Chinese medicinal oral and topical stock solution mixture for treating metabolic syndrome and resisting bacteria and inflammation Download PDF

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CN112076305A
CN112076305A CN201910528945.3A CN201910528945A CN112076305A CN 112076305 A CN112076305 A CN 112076305A CN 201910528945 A CN201910528945 A CN 201910528945A CN 112076305 A CN112076305 A CN 112076305A
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dried
inflammation
treating
oral
stock solution
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汪春发
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Abstract

The invention discloses a traditional Chinese medicine stock solution mixture. The formula synthesis comprises: 180g of seaweed, 160g of dried orange peel, 800mg of cordyceps militaris, 190g of ampelopsis grossedentata tea, 180g of dendrobium, 160g of pummelo peel, 30g of red date, 90g of white poria, 16g of dried pawpaw seed, 15g of dried pineapple flower, 60g of hawthorn, 90g of astragalus, 80g of dried liquorice, 80g of mulberry, 20g of black fungus, 60g of dried ginger, 30g of wormwood and 90g of green tea. The preparation method comprises the following steps: decocting the raw materials in water for four times, mixing, filtering, and extracting twice by distillation. The curative effect is as follows: 1. the oral preparation can be used for treating symptoms caused by metabolic syndrome of human body, has no side effect, and is suitable for treating obesity, insomnia, alopecia, edema, gastritis, diabetes, hypertension, hyperglycemia, hyperlipidemia, gout, tumor, numbness, vertigo, halitosis, constipation, etc. 2. The external preparation has effects of sterilizing, diminishing inflammation, relieving itching and detumescence, has no harm to human skin, and is suitable for treating corner ulcer, oral ulcer, toothache, acne, nasopharyngitis, pruritus, wound inflammation, paronychia, onychomycosis, tinea pedis, bromhidrosis, foot odor, hemorrhoid, etc. The using method comprises the following steps: the oral administration is 30ml, the oral administration is divided into 2 times, the effect is achieved within one week, and the cure can be realized in one to two treatment courses; 2. can be applied for many times for external use, has effect in one day, and can be cured in three to five days.

Description

A Chinese medicinal oral and topical stock solution mixture for treating metabolic syndrome and resisting bacteria and inflammation
Technical Field
A Chinese medicinal oral and topical stock solution mixture for treating metabolic syndrome and resisting bacteria and inflammation is provided. The Chinese medicinal raw liquid mixture has the following curative effects:
the medicine is taken orally to treat the symptoms caused by human metabolic syndrome without side effect.
Oral administration: treating phlegm dampness obesity, insomnia, alopecia, edema, gastritis, diabetes, hypertension, hyperglycemia, hyperlipidemia, gout, tumor, numbness, vertigo, halitosis, constipation, etc. caused by metabolism syndrome disorder.
Secondly, the external use has the functions of sterilization, inflammation diminishing, sterilization, itching relieving and swelling diminishing, and has no harm to the skin of the human body.
External use: has antibacterial, antiinflammatory, antipruritic, and repercussive effects, and is suitable for treating corner ulcer, oral ulcer, toothache, acne, nasopharyngitis, pruritus, wound inflammation, paronychia, onychomycosis, tinea pedis, bromhidrosis, foot odor, and hemorrhoid.
The invention relates to a group of traditional Chinese medicine formulas, belonging to the technical field of traditional Chinese medicine preparation stock solution mixture for oral administration and external use.
Background
The pathological state of the human metabolic disorder is also a complex group of metabolic syndromes and has the following characteristics:
firstly, the human body is obese due to phlegm-dampness constitution. Mainly refers to the dysfunction of human viscera, which easily causes the dysfunction of transportation and transformation of qi, blood and body fluids, water-dampness accumulation and accumulation of dampness to form phlegm-body obesity, often forms obesity, abdominal fullness, chest distress, excessive phlegm, easy drowsiness, swollen tongue, white and greasy tongue coating, easy thirst, apoplexy, chest impediment and the like, and has poor adaptability to plum rain and damp heavy environment. People with wet constitution can not eat fat, sweet, thick and cold raw materials, stop smoking, improve the intake of rich fiber and vitamins, and keep defecate smooth and normal. The dried pineapple flowers, the dried pawpaw seeds, the mulberry, the astragalus, the dried liquorice, the white poria, the dried tangerine peel, the pummelo peel, the red dates and the wormwood are as follows: rich in fiber and vitamins, has effects of promoting defecation, invigorating spleen, eliminating phlegm, and promoting qi and blood circulation. The spleen is the source of phlegm generation, and the lung is the device for storing phlegm, so that the spleen is strengthened, phlegm is reduced, wading rain is avoided, people stay in the wet land for a long time, the people pay attention to heat preservation, the spleen is prevented from being injured by external cold-dampness, and the spleen is prevented from being trapped, and the people are suitable for physical exercise and are smooth in qi and blood due to slight sweat.
Secondly, facial wrinkles and dull complexion. The skin is influenced by the external environment and the skin itself to form free radicals, the free radicals destroy collagen and active substances in normal cell membrane tissues, the collagen content of the skin dermis layer is gradually reduced, the reticular supporting body is thickened, hardened and loses elasticity, the elasticity and the water retention degree of the dermis layer are reduced, the skin loses elasticity, becomes thin and ages, the skin becomes loose and wrinkles appear due to the reduction of fat of the fat pad under the eyelid, and no matter the wrinkles, the fishtail lines, the fine lines and the eye tail lines are all caused by the uneven collapse of the skin epidermis. When a human body enters the canthus at about 25 years old, shallow small wrinkles and eye bags may appear; the forehead wrinkles deepen and increase around 25 years old, and the external canthus has fishtail lines and the upper eyelid skin has wrinkles; the nasolabial sulcus deepens when the patient is aged 40 years, fine wrinkles appear at the corners of the mouth, and wrinkles appear at the neck; the 50 year old eye bags deepen and appear with lower eyelid lines, and the upper and lower lips also appear with wrinkles; the elasticity of the face is reduced and the wrinkles are deepened by the age of 60. When the collagen content in the skin is gradually reduced, the dermal fiber is broken, the lipoatrophy, the sweat gland and sebaceous gland secretion is reduced, and the skin has the aging phenomena of color spots, tarnish, looseness, wrinkles and the like. Seaweed, astragalus, dried liquorice, white poria, dried tangerine peel, cordyceps militaris, pummelo peel, red dates, hawthorn, dried ginger, ampelopsis grossedentata tea, wormwood, green tea and dendrobium nobile supply sufficient skin nutrition, subcutaneous tissues are full, collagen connective tissues are adopted, skin is lubricated, and wrinkles are removed. Green tea contains more than 400 kinds of abundant chemical components, mainly contains tea, phenols, aromatic oil compounds, carbohydrates, proteins, various amino acids, vitamins, minerals, pectin and the like. Is a natural body-building beverage, can promote health, keep skin smooth and clean, delay facial wrinkles, support skin cells, and achieve the effects of removing wrinkles, whitening skin, removing freckles, removing pouches and the like.
Third, face edema, acne, fatigue, soreness of the waist and back pain. The kidney manages the running of liquid in the body, and after toxin is accumulated on the kidney, the capacity of discharging redundant liquid is reduced, so that edema occurs; the kidney of the lower jaw part of the face is controlled, the toxin expelling of the kidney is insufficient, the redundant toxin can be shown in the lower jaw part, and the lower jaw has acne; the energy of the kidney is consumed by toxins in the body, and the energy supplied by the kidney is reduced, so that the symptoms of tiredness, mental fatigue, sleepiness, weakness of limbs, soreness of waist and back pain appear. Cordyceps has effects of invigorating kidney, nourishing liver, replenishing essence, improving eyesight, strengthening tendons and bones, relieving lumbago, replenishing essence, and strengthening tendons and bones, and can be used for treating asthenia, emaciation, lassitude, giddiness, deafness, dim eyesight, and soreness of waist and knees. The agaric can ensure the metabolism of the kidney, reduce the accumulation of redundant water in the kidney, the vegetable protein is beneficial to the kidney, and the phytoestrogen has the effect of protecting the kidney; the astragalus, the dried liquorice, the white poria, the dried orange peel, the cordyceps militaris, the pummelo peel, the red dates, the hawthorns, the dried ginger, the ampelopsis grossedentata tea, the wormwood, the green tea and the dendrobium have the effects of nourishing blood and liver, securing essence and tonifying the kidney, strengthening bones and muscles, blackening hair and improving eyesight, filling blood, building walking, soreness and pain in the waist and back, weak feet and knees and the like.
In diabetes, such as insulin deficiency, glucose entering tissue cells is reduced, and hepatic glycogen breakdown and xenogenesis are enhanced. Glucose released into the blood by the liver increases greatly, blood glucose levels rise and are excreted from the urine beyond the renal glucose threshold, manifesting as diabetes. Dried pineapple flowers, dried pawpaw seeds, mulberry, black fungus, seaweed, astragalus, dried liquorice, white poria, dried tangerine peel, cordyceps militaris, pummelo peel, red dates, hawthorn, dried ginger, maoyanmei tea, wormwood, green tea and dendrobium contain bicarbonate and various digestive enzymes for exocrine pancreatic juice of pancreas, neutralize gastric acid, and digest sugar, protein and fat. 1. Promotes the synthesis of liver glycogen and muscle glycogen, which is mainly achieved by increasing the activity of glycogen synthase in the liver and muscle. 2. Promoting glucose to enter muscle and fat tissue cells. 3. The glucolase is activated to produce glucose-6-phosphate. 4. Inhibiting gluconeogenesis. Prevention: abstinence from alcohol, overeating, light diet, eating carbohydrates and proteins.
And fifthly, halitosis, macula pox and constipation, which means that many people have no intention to lift after defecating, harmful bacteria in intestines accumulate for a long time, and the harmful bacteria continuously utilize the harmful bacteria to generate toxic substances, so that the large intestine full of foul smell is formed. Halitosis is a gas produced by abnormal fermentation in the intestine, a gas that enters the blood from the large intestine and is then transported to the lungs, and is discharged from the mouth together with respiration, causing halitosis; the constipation is called as 'origin of diseases', the constipation directly increases the stool of the intestinal tract, the stool produces various toxins, generally about 40 hundred million toxins, and when the number of harmful toxins reaches 200 million, the intestinal tract movement is hindered, the intestinal peristalsis and the swinging of intestinal villi are weakened, the feces stagnate and start to decay in the intestine, and the produced harmful substances are absorbed by the intestine, and then the toxins gradually appear on the naked skin of the human body in the morning and the evening, such as color spots and dark skin on the hands, the health condition of the intestinal tract is known by observing the complexion, and acne is generated on the face with low immunity, namely acne, and a lot of diseases are caused. The five zang organs descend qi to regulate the middle energizer, but do not have lung qi, so the lung and large intestine meridians are communicated to moisten the intestines for relaxing bowels; tonify kidney qi, kidney qi deficiency, blood vessel is not alive. The dried orange peel, cordyceps militaris, pummelo peel, red date, hawthorn, dried ginger, ampelopsis grossedentata tea, wormwood, dendrobium, mulberry, green tea and seaweed are added with plant cellulose, are rich in oil, supplement prebiotics, clear heat, moisten intestines, detoxify, relieve lung qi, supplement kidney qi, clear heat, resolve phlegm, remove food retention, moisten intestines, digest, expel toxin and defecate.
Sixthly, when the user sleeps, the mouth is flushed on one side, the head is dizzy, the limbs are swollen, the chest is stuffy and painful, the body breathes and the heartbeat are rapid, and the upper signals are sent out by the body, which indicates that the thrombus and blood clots are formed in the blood vessels. The blood clots are called thrombus, and block the blood vessels of different parts of the body like plugs, so that once the blood vessels are blocked, the blood transportation system is paralyzed, the related visceral organs have no blood supply, sudden death is caused, and the life and health are seriously threatened. Specifically, the method comprises the following steps: 1. when sleeping, the saliva flows on one side, because thrombus can cause dysfunction of the pharyngeal cavity muscles. 2. Dizziness in the head, which is the most typical symptom of cerebral thrombosis precursor, is very common, and can occur at any time before cerebrovascular disease, especially when getting up in the morning, and also easily occurs after fatigue and bathing, especially in hypertension patients, if dizziness occurs more than 5 times repeatedly in 1-2 days, the risk of cerebral hemorrhage or cerebral infarction is increased. 3. Swelling of the extremities, which is one of the typical symptoms of deep vein thrombosis, is especially noted when rapid swelling and pain in the thighs occurs. Swelling occurs over time because of the thrombus which can cause the blood flow in the legs to be blocked. 4. Chest distress and pain, and long-term lack of motion can easily cause blood to form venous clots. Furthermore, blood clots may break off, following the blood flow into the lungs. If the thrombus is larger or more, the thrombus can be blocked on the branch or trunk of the pulmonary artery, large-area pulmonary infarction is caused, discomfort such as chest distress, chest pain, cough, respiratory obstruction and the like occurs, and the life can be seriously threatened. 5. The patient feels that the chest and heart beat are accelerated and the breath becomes shallow due to rapid respiration and heartbeat, which are signals for asking for help of the body, and the lung meets the pulmonary embolism and seriously falls down. The health food contains fructus Ananadis Comosi dried flower, fructus Chaenomelis dried seed, Mori fructus, pericarpium Citri Tangerinae, scarlet caterpiller fungus, exocarpium Citri Grandis, fructus Jujubae, fructus crataegi, Zingiberis rhizoma, fructus Jujubae, Sargassum, Auricularia, and green tea, and can inhibit absorption of cholesterol by human body and regulate blood lipid; the n-3 fatty acid, folic acid and potassium can keep artery vessel smooth and is beneficial to heart. The polyphenol substance, anthocyanin, helps to promote blood circulation and metabolism, and actively transmit to the whole body to enhance endocrine function. The sulfated polysaccharide can absorb cholesterol in blood vessel and discharge it to outside of body, so as to keep cholesterol in blood at normal content, and is rich in dietary fiber and colloid, and the colloid component can combine with harmful substances in blood, such as heavy metal, and has effects of removing toxic substance, purifying blood, and improving blood vessel patency.
Seventhly, enzyme digestion, thrombus prevention and treatment, inflammation diminishing and sterilization. The human body contains more than 700 kinds of enzymes distributed in the oral cavity, gastrointestinal tract, pancreas, liver, muscle and skin of the human body, and with the age, the enzymes in other parts of the body are consumed in metabolism, and the enzymes are needed for other body organs and systems to normally function, and the harm to the health of the body is larger when the more the enzymes are consumed. The dried pineapple flowers, the dried pawpaw seeds, the mulberry, the black fungus, the seaweed, the astragalus mongholicus, the dried liquorice, the white poria, the dried tangerine peel, the cordyceps militaris, the pummelo peel, the red dates, the hawthorn, the dried ginger, the maoyanmei tea, the wormwood, the green tea and the dendrobium have the following effects: proteases convert proteins to amino acids, amylases convert starch to glucose, and lipases break down fats to fatty acids. And (3) nutrition generation: nutrients such as saccharides, organic acids, minerals, vitamins, phenols, terpenes, etc.; physiologically active substance: vitamins, amino acids, polysaccharides, peptides, polyphenols, flavonoids, mineral elements and organic acids, antioxidant components such as GABA, SOD, catalase, etc., and antioxidant components such as probiotics and microorganisms such as flavonoids, isoflavones, saponin, etc. The specific effects are as follows: 1. helping digestion. (1) Digestive enzymes-flatulence, nausea. (2) Improving immunity. (3) The enzyme can promote effective metabolism, avoid pseudo-hunger generated by digestion, and naturally and stably reduce weight. (4) Digestive enzymes promote cardiovascular health. Reduce the formation of arterial obstruction of fat precipitation, protease, trypsin, papain, amylase, lipase can all help digestion. 2. Can be used for preventing and treating thrombosis. Streptokinase, urokinase and plasmin can dissolve thrombus and prevent thrombosis, and can be used for treating cerebral thrombosis and myocardial infarction. 3. Diminishing inflammation and sterilizing. The health-care food is prepared from flavonoids, lysozyme, bromelain and papain, can relieve inflammation, promote detumescence and surgical sore removal, and is flavonoid, antioxidant, bactericidal and anti-inflammatory to provide organism immunity.
Disclosure of Invention
The invention provides a group of raw liquid mixtures prepared by traditional Chinese medicine formulas, which are used for treating human metabolic syndrome and related symptoms of sterilization and inflammation diminishing, and the traditional Chinese medicine raw liquid mixture has definite curative effect, is taken orally and has no toxic or side effect; it is applied externally and has no damage to skin.
The parts are mass parts, and are microgram, milligram, gram, kilogram and other mass units commonly used in the field.
A Chinese medicinal oral and topical stock solution mixture for treating metabolic syndrome and resisting bacteria and inflammation is provided. The technical scheme of the formula adopted by the invention is as follows: the tea is prepared from the following raw materials of dried pineapple flowers, dried pawpaw seeds, mulberry, black fungus, seaweed, astragalus mongholicus, dried liquorice, white poria, dried orange peel, cordyceps militaris, pummelo peel, red dates, hawthorn, dried ginger, maoyanmei tea, wormwood, green tea and dendrobium by mass: 320 parts of seaweed 180-.
A Chinese medicinal oral and topical stock solution mixture for treating metabolic syndrome and resisting bacteria and inflammation is provided. The preferable formula is synthesized, and specifically: 180g of seaweed, 160g of dried orange peel, 800mg of cordyceps militaris, 190g of ampelopsis grossedentata tea, 180g of dendrobium, 160g of pummelo peel, 30g of red date, 90g of white poria, 16g of dried pawpaw seed, 15g of dried pineapple flower, 60g of hawthorn, 90g of astragalus, 80g of dried liquorice, 80g of mulberry, 20g of black fungus, 60g of dried ginger, 20g of wormwood and 90g of green tea.
A Chinese medicinal oral and topical stock solution mixture for treating human metabolic syndrome and resisting bacteria and inflammation is prepared by: decocting the raw materials in water for four times: adding 10 times of water for the first time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 8 times of water for the second time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 6 times of water for the third time, boiling for 2 hr, and decocting with slow fire for 4 hr; adding 5 times of water for the fourth time, boiling for 1 hr, decocting with slow fire for 4 hr, mixing decoctions, and sieving with 300-mesh 400-mesh filter screen to obtain the final product. Putting the filter screen decoction into a multifunctional traditional Chinese medicine extraction tank, extracting by adopting a steam distillation method, putting Cordyceps militaris and herba Dendrobii powder bags (1 g of Cordyceps militaris and 200g of herba Dendrobii) while decocting, distilling, condensing, collecting distillation stock solution (2 times by distillation method), and filling.
The oral administration and external application method of the stock solution mixture has the daily dose of 30ml, and the stock solution mixture is taken by 2 times, specifically 15ml (about 80ml of white boiled water in a half cup and 50-60 ℃) respectively taken by half an hour after lunch in the morning on an empty stomach. Oral administration: in the aspect of treating symptoms caused by human metabolic syndrome, 20 days are taken as a treatment course, the effect is usually achieved within one week, and the symptoms can be cured in one to two treatment courses; external use: has the effects of sterilizing, diminishing inflammation, relieving itching and reducing swelling, and can be cured in three to five days.
The formula is as follows:
the dried pineapple flowers are neutral in nature, sweet in taste, slightly sour, slightly astringent and slightly cold in nature, and have the curative effects of promoting digestion, relieving diarrhea, tonifying spleen and stomach, strengthening vitality, tonifying qi and blood, promoting digestion, eliminating dampness and treating constipation. Among them, bromelain decomposes proteins, helps digestion, dissolves fibrin and blood clots that block tissues, improves blood circulation, dilutes blood lipids, eliminates inflammation and edema, promotes blood circulation, and prevents fat deposition. The enzyme can decompose protein in stomach, supplement digestive enzyme deficiency in human body, and prevent gel aggregation, so as to restore normal digestive function for people with dyspepsia. In addition, sugar and enzyme contained in pineapple have a certain diuretic effect, and are beneficial to nephritis and hypertension patients, and also have adjuvant therapeutic effect on bronchitis and therapeutic effect on constipation by cellulose. Besides, the pineapple is rich in vitamin B1, and can promote metabolism, relieve fatigue and reduce the incidence of cardiovascular and cerebrovascular diabetes.
The papaya seed dried food contains papaya protease, carotene and vitamin C, has antioxidant capacity, helps organism repair tissue, eliminates toxic substances, and enhances immunity. Specifically, the method comprises the following steps: 1. supplementing nutrition, and fructus Chaenomelis contains large amount of water, carbohydrate, protein, fat, multiple vitamins and amino acids, and can supplement nutrition and enhance antivirus ability of human body. 2. The food has the effects of invigorating spleen to promote digestion, and decomposing fat into fatty acid and decomposing protein into amino acid by using papain, thereby facilitating digestion and absorption of food by human body. 3. Antibacterial effect, and has effects in resisting Bacillus tuberculosis and killing parasite. 4. Has antispasmodic effect, and can relieve spasm pain symptom and has obvious effect on gastrocnemius spasm.
Mulberry, cold in nature, produces saliva, contains tannic acid, fatty acid, malic acid, fatty acid, linoleic acid, stearic acid, vitamins, carotene and trace elements. Comprising: improving blood supply of skin (including scalp), nourishing skin, whitening skin, blackening hair, delaying aging, improving eyesight, relieving eye fatigue and dryness, enhancing spleen and hemolytic reaction, preventing arteriosclerosis and skeleton arthrosis, promoting metabolism, promoting red blood cell growth, preventing leukopenia, and treating diabetes, anemia, hypertension, hyperlipemia, coronary heart disease, neurasthenia, etc. Specifically, the method comprises the following steps: 1. the fatty acids in mulberry mainly comprise linoleic acid, oleic acid, palmitic acid, stearic acid and a small amount of caprylic acid, pelargonic acid, capric acid, myristic acid, linolenic acid and the like, and have the effects of decomposing fat, reducing blood fat, preventing angiosclerosis and the like. 2. The mulberry contains tannic acid, fatty acid, malic acid and the like, helps digestion of fat, protein and starch, has the functions of strengthening spleen and stomach and helping digestion, and is used for treating diarrhea caused by dyspepsia. 3. The nutritious mulberry contains abundant vitamins, carotene and trace elements, and can effectively expand blood volume of human body, and is suitable for patients with hypertension and women. 4. Mulberry contains hair blackening agent, and can make hair black and bright.
Black fungus, nature and taste: sweet, mild and non-toxic. Comprising: nourishing, moistening dryness, nourishing blood, benefiting stomach, promoting blood circulation, stopping bleeding, moistening lung, and moistening intestine, and can be used for treating hyperlipidemia, invigorating qi, relieving hunger, treating hemorrhoid, relaxing muscles and tendons, activating collaterals, blood deficiency, qi deficiency, tetany, cough due to lung deficiency, bloody dysentery, and tranquilizing mind and relieving pain. The Auricularia polysaccharide has radioprotective effect superior to that of Tremella polysaccharide, and can resist leukocyte decrease caused by cyclophosphamide. The proteins, fats and saccharides contained in the black fungus are not only essential nutrient components for human bodies, but also material bases for beautifying. The carotene is converted into vitamin A after entering human body, which has the function of moistening skin and hair, the lecithin can make the fat in the body in a liquid state, which is beneficial to the complete consumption of the fat in the body and the drive of the fat in the body to move, so that the fat is distributed reasonably and has a uniform body shape. The cellulose can promote enterokinesia and fat excretion, and is beneficial for weight reduction.
Seaweed, nature and taste, bitter, salty, cold, nontoxic. Improve lung, spleen, kidney, liver and stomach, and has the following effects: softening hard mass, eliminating phlegm, promoting diuresis, relieving swelling, abdominal mass, distending pain, hollow belly, edema, and treating skin accumulation, stagnation of qi, heat accumulation, diuresis, and loempe. Specifically, the method comprises the following steps: 1. the carrageenans of red algae are sulfated galactose polymers, and these polysaccharides have the effect of enhancing immunity. 2. Dietary fiber. The dietary fiber is macromolecule with polysaccharide structure, is main component constituting seaweed cell wall, and has effects of improving hyperlipemia symptoms, inhibiting blood cholesterol content, regulating and controlling blood sugar amount, increasing intake of seaweed fiber, lowering blood pressure, blood cholesterol and blood sugar amount, and protecting heart and blood vessel. 3. Vitamins: when a certain vitamin is deficient or deficient in a human body, metabolic disorder or disease is caused, and the seaweed contains various vitamins (vitamins B12, C and E, biotin and nicotinic acid), so that the deficiency of iodine in the human body is improved to cause thyroid dysfunction. 4. A fatty acid. Fatty acids are usually present in the deep sea algae in high amounts, and can help to lower blood pressure, heartbeat and relieve stress, and can also inhibit blood cholesterol level increase and platelet aggregation, prevent thrombosis and myocardial infarction, and prevent arteriosclerosis and circulatory system diseases. 5. Alginic acid sulfonic acid has anticoagulant and hemostatic effects. The alginic acid can prevent blood coagulation disorder after sulfonation, and has anticoagulant and topical hemostatic effects. 6. Alginic acid and amphetamine with equal molecules can relieve obesity without causing insomnia, and eliminate body odor, foot odor and other unpleasant odors.
Huang Qi is sweet in flavor and slightly warm in nature. The astragalus contains calycosin, 3-hydroxy-9, 10-dimethoxy rosewood alkane and astragalus saponin, and has the main functions of treating spleen and lung: invigorating qi, consolidating superficial resistance, removing toxic substances, expelling pus, promoting urination, and promoting granulation. Can be used for treating deficiency of vital energy, asthenia, chronic diarrhea, rectocele, spontaneous perspiration, edema, chronic nephritis, albuminuria, diabetes, and unhealed wound.
Dried liquorice, dried liquorice root and rhizome, sweet taste and mild nature. Improving heart, lung, spleen and stomach channels, invigorating spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and relieving cough, and relieving spasm and pain. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature. Specifically, the method comprises the following steps: 1. it can be used for treating heart-qi deficiency, palpitation, intermittent pulse, spleen and stomach qi deficiency, listlessness, and asthenia. 2. It is used to treat carbuncle, ulcer, sore and sore throat. 3. Can be used for treating asthma and cough. 4. Can be used for treating stomach ache, abdominal pain, and acute pain of gastrocnemius muscle spasm. 5. The adrenocortical hormone has the effects of inhibiting hyperacidity caused by histamine, resisting acid and relieving gastrointestinal smooth muscle spasm. 6. Licoflavone, glycyrrhiza extract and glycyrrhetinic acid all have obvious cough relieving effect. 7. The Glycyrrhrizae radix has antiinflammatory and antiallergic effects, and can protect inflamed throat and trachea mucosa. 10. Licorice is commonly used to treat symptoms accompanying menopause because it contains liquiritigenin, a hormone-like compound that helps to balance the hormone content in women.
Poria cocos is sweet, light and flat in taste, improves heart, spleen, lung and kidney channels, has pachyman, B-pachyman, pachymic acid, lecithin, sterol and the like, and has the effects of excreting dampness and promoting diuresis, strengthening spleen and stomach, calming heart and tranquilizing mind, dysuria, edema and fullness, phlegm and fluid retention and cough, vomiting, spleen deficiency and poor appetite, diarrhea, palpitation and uneasiness, insomnia and amnesia. Poria has antibacterial effect, and pachyman complex have inhibiting and killing effects on Staphylococcus aureus, Escherichia coli, Bacillus proteus, etc.
Tangerine peel, pericarpium Citri Tangerinae, bitter in taste, pungent and warm in nature, enters lung and spleen meridians. Pericarpium Citri Tangerinae has pharmacological effects of treating stagnation of spleen and stomach qi, dampness obstruction, fullness and oppression in chest and diaphragm, abdominal pain, anorexia, emesis, constipation, obstruction of lung qi, cough, and excessive phlegm. Specifically, the method comprises the following steps: first, fullness and distention of chest and abdomen. 1. Tangerine peel, pericarpium Citri Reticulatae is pungent and fragrant in flavor, good at regulating qi, entering spleen and lung, promoting qi circulation and relieving epigastric distention, stagnation of lung qi, damp obstruction of middle energizer, abdominal distention, loose stool, diarrhea, excessive phlegm and cough. 2. Tangerine peel, pericarpium Citri Tangerinae and Poria are used together to strengthen the spleen and promote the circulation of qi, damp obstruction of middle energizer, abdominal distention and fullness, loose stool and greasy coating. 3. Can be used for treating spleen deficiency, anorexia, dyspepsia, nausea, and emesis. 4. Eliminating dampness and phlegm, phlegm-dampness obstructing the lung, fullness and oppression in chest and diaphragm, dizziness and vertigo. 5. Can be used for treating edema, dysuria, and constipation. Secondly, the function of the digestive system. The pericarpium Citri Tangerinae contains volatile oil, has mild irritation to gastrointestinal tract, and has effects of promoting secretion of digestive juice, eliminating intestinal tract pathogenic accumulation, invigorating stomach, dispelling pathogenic wind, and descending qi. And thirdly, the effect on the cardiovascular system. The pectin in pericarpium Citri Tangerinae has certain effect in preventing arteriosclerosis caused by high fat diet. And fourthly, the effect on a respiratory system. The pericarpium Citri Tangerinae volatile oil has effects of eliminating phlegm, relieving asthma, and slightly dilating bronchus. Fifth, the action on the urogenital system can cause the renal blood vessels to contract, so that the urine volume is normal. Sixthly, the anti-inflammatory effect is achieved, and the tangerine peel vitamin C and the vitamin K can enhance the anti-inflammatory effect. And influence on blood fat, and the tangerine peel pectin has the effect of reducing hyperlipidemia.
Cordyceps militaris is sweet and neutral in taste, and enters lung and kidney meridians, and has the effects of tonifying deficiency, benefiting vital essence, relieving cough and reducing sputum. The cordyceps militaris contains about 7 percent of cordycepic acid, about 25 percent of protein and about 8.4 percent of fat, wherein 82.2 percent of the cordycepic acid is unsaturated fatty acid which cannot be synthesized by a human body and is necessary, 28.9 percent of carbohydrate, 12 free amino acids, 18 hydrolysate amino acids, 8 amino acids which are necessary for the human body and histidine which is necessary for the growth and development of children. In addition, cordycepic acid, cordycepin, amino acids, sterol, mannitol, alkaloid, vitamin B1, B2, polysaccharide and minerals have effects of nourishing kidney, resisting arrhythmia, relieving fatigue, eliminating phlegm and relieving asthma, tranquilizing, hypnotizing, resisting bacteria, resisting inflammation and regulating immunity.
Exocarpium Citri Grandis, pungent and bitter in flavor, warm in nature, enters lung and spleen meridians, regulates qi, relieves epigastric distention, eliminates dampness and resolves phlegm. The pummelo peel mainly comprises flavanone, naringin and mutual peptide which are used for treating the diseases: cough with excessive phlegm, dyspepsia, alcoholic intoxication, nausea, distention, cold expelling, dampness eliminating, qi circulation promoting, diseases eliminating, cough relieving, spleen invigorating, digestion promoting, and cardiovascular and cerebrovascular health promoting effects.
The red date is sweet in taste and warm in nature, and has the functions of tonifying middle-jiao and Qi, nourishing blood and soothing nerves and relieving drug property, and spleen and stomach meridians are entered. The fructus Jujubae contains protein, saccharide, organic acid, vitamin A, vitamin C, various trace calcium and amino acids. Wherein, the flavonoids, the triterpenoids and the cyclic adenosine monophosphate have strong effects of inhibiting cancer, resisting allergy, resisting fatigue, damaging liver, lowering blood pressure, nourishing blood, calming the nerves, nourishing spleen and stomach, enhancing myocardial contractility and improving cardiac muscle.
Haw is sour and sweet in taste, slightly warm, and enters spleen, stomach and liver meridians. The fructus crataegi contains flavonoids, vitexin, quercetin, quercitrin, hyperoside, 7-glucoside, rutin, crataegolic acid, citric acid, ursolic acid, phospholipid, vitamin C, vitamin B2 and compounds. It can be used for treating dyspepsia, blood stasis, taenia, meat stagnation, abdominal mass, phlegm retention, acid regurgitation, dysentery, intestinal wind, lumbago, dyspepsia, abdominal pain, pain in heart and abdomen, and hyperlipidemia.
Gan Jiang is pungent in flavor and warm in nature and enters lung, stomach and spleen meridians. The main components are as follows: gingerol, shogaol, anis, borneol, gingerol, shogaone, zingerone and olein. The main treatment is as follows: relieving exterior syndrome, dispelling cold, warming middle warmer, relieving vomit, warming lung, relieving cough, promoting metabolism, dredging channels and collaterals, relieving stomach cold, anorexia, promoting gastric secretion, promoting digestion, invigorating stomach, promoting blood circulation, replenishing vital essence, improving eyesight, aversion to cold, lumbago, soreness of waist and knees, listlessness, ulcer, and gastritis due to deficiency-cold. Simultaneously has the functions of killing oral pathogenic bacteria and intestinal pathogenic bacteria and promoting blood circulation.
The mugwort is bitter, pungent and warm in taste, enters spleen, liver and kidney, is warm in nature, bitter in taste and nontoxic. It contains volatile oil, eucalyptol, thujone, sesquiterpene alcohol, fat, protein, biotin A, B1, B2, C, etc. Comprising: regulating qi and blood, dredging meridian passage, relieving swelling, dispersing pathogen accumulation, stopping bleeding, relieving inflammation, relieving asthma, relieving cough, resisting allergy, treating rheumatic arthritis, and resisting bacteria and inflammation.
Ampelopsis grossedentata tea containing 17 amino acids such as leucine, isoleucine, methionine, etc., and 14 microelements such as potassium, calcium, iron, zinc, magnesium, etc.; especially contains high-activity flavone and dihydromyricetin. The curative effect is as follows: 1. the flavone contained in the Ampelopsis grossedentata can eliminate harmful acid and ketone bodies of a human body, remove blood dirt in blood, regulate blood fat, reduce blood pressure, has obvious effect of softening blood vessels, can regulate renal tubule reabsorption, improve sleep, frequent micturition and the like 2. the flavone contained in the Ampelopsis grossedentata can sterilize bacteria, resist inflammation, clear away heat and toxic materials, relieve pain, reduce swelling, reduce fat and blood pressure, moisten throat, relieve cough and regulate and improve human immunity and has strong killing capability on staphylococcus aureus, streptococcus A, streptococcus B, diplococcus pneumoniae, bacillus influenzae and the like.
Green tea, tea polyphenols, catechins ECG, EGC and theaflavins. Comprising: refreshing, clearing away heart-fire, clearing away summer-heat, resolving food stagnation, eliminating phlegm, reducing weight, clearing heart-fire, relieving restlessness, removing toxic substance, relieving hangover, promoting salivation, quenching thirst, purging pathogenic fire, improving eyesight, relieving dysentery, removing dampness, and treating cardiovascular and cerebrovascular diseases. The main components of the tea beverage comprise tea polyphenol, caffeine, lipopolysaccharide and theanine. Comprising: delaying aging, resisting oxidation, scavenging free radicals, inhibiting cardiovascular diseases, and improving fat metabolism; the contents of cholesterol, triglyceride and the like are high, and the lipid-rich atherosclerosis-resistant tea has the effects of inhibiting atheromatous plaques formed after fat deposition on the inner wall of a blood vessel and proliferation of smooth muscle cells of the blood vessel, reducing fibrinogen with enhanced blood coagulation viscosity and clearing blood coagulation, thereby inhibiting atherosclerosis and virus resistance.
Dendrobium nobile, sweet in flavor and slightly cold in nature, enters stomach and kidney meridians. The main components are as follows: dendrobine, dendrostelline, dendrobine, 6-hydroxydendrobine, fresh dendrostelline, mucilaginous substance, starch, dendrobine, N-methyl dendrobine, and dendrobine. Has the following treatment: benefiting stomach and promoting fluid production, nourishing yin and clearing heat, fever and body fluid impairment, xerostomia and polydipsia, stomach yin deficiency, anorexia and retching, dim and unclear vision, flaccidity of tendons and bones, and the like.
Detailed Description
The invention relates to a traditional Chinese medicine prepared stock solution mixture for oral administration and external use for treating human metabolic syndrome and sterilizing and diminishing inflammation, which has the following curative effects:
the medicine is taken orally to treat the symptoms caused by human metabolic syndrome without side effect.
Oral administration: treating phlegm dampness obesity, insomnia, alopecia, edema, gastritis, diabetes, hypertension, hyperglycemia, hyperlipidemia, gout, tumor, numbness, vertigo, halitosis, constipation, etc. caused by metabolism syndrome disorder.
Secondly, the external use has the functions of sterilization, inflammation diminishing, sterilization, itching relieving and swelling diminishing, and has no harm to the skin of the human body.
External use: has antibacterial, antiinflammatory, antipruritic, and repercussive effects, and is suitable for treating corner ulcer, oral ulcer, toothache, acne, nasopharyngitis, pruritus, wound inflammation, paronychia, onychomycosis, tinea pedis, bromhidrosis, foot odor, and hemorrhoid.
The invention is further described.
In order to realize the above curative effect, the invention provides the following technical scheme:
example 1: a Chinese medicine oral and external use stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation is used as a further scheme of the invention: 230g of seaweed, 130g of dried orange peel, 400mg of cordyceps militaris, 120g of ampelopsis grossedentata tea, 120g of dendrobium, 110g of pummelo peel, 30g of red date, 120g of white poria, 10g of dried pawpaw seed, 8g of dried pineapple flower, 80g of hawthorn, 120g of astragalus root, 120g of dried liquorice, 90g of mulberry, 20g of black fungus, 60g of dried ginger, 20g of wormwood and 80g of green tea. Decocting the raw materials with water twice: adding 10 times of water for the first time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 8 times of water for the second time, boiling for 2 hr, decocting with slow fire for 4 hr, mixing decoctions, and filtering with 300-mesh 400-mesh filter screen to obtain the final product. Putting the filter screen decoction into a multifunctional traditional Chinese medicine extraction tank, extracting by adopting a steam distillation method, condensing, collecting a distillation stock solution, and filling to obtain the traditional Chinese medicine.
Example 2: a Chinese medicine oral and external use stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation is used as a further scheme of the invention: 240g of seaweed, 140g of dried orange peel, 300mg of cordyceps militaris, 110g of ampelopsis grossedentata tea, 110g of dendrobium, 120g of pummelo peel, 30g of red date, 130g of white poria, 9g of dried pawpaw seed, 6g of dried pineapple flower, 90g of hawthorn, 140g of astragalus root, 130g of dried liquorice, 80g of mulberry, 20g of black fungus, 60g of dried ginger, 10g of wormwood and 90g of green tea. Decocting the raw materials with water twice: adding 10 times of water for the first time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 8 times of water for the second time, boiling for 2 hr, decocting with slow fire for 4 hr, mixing decoctions, and filtering with 300-mesh 400-mesh filter screen to obtain the final product. Putting the filter screen decoction into a multifunctional traditional Chinese medicine extraction tank, extracting by adopting a steam distillation method, condensing, collecting a distillation stock solution, and filling to obtain the traditional Chinese medicine.
Example 3: a Chinese medicine oral and external use stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation is used as a further scheme of the invention: 260g of seaweed, 120g of dried orange peel, 200mg of cordyceps militaris, 90g of ampelopsis grossedentata tea, 80g of dendrobium, 110g of pummelo peel, 30g of red date, 150g of white poria, 6g of dried pawpaw seed, 5g of dried pineapple flower, 90g of hawthorn, 180g of astragalus, 160g of dried liquorice, 60g of mulberry, 20g of black fungus, 60g of dried ginger, 8g of wormwood and 120g of green tea. Decocting the raw materials with water for three times: adding 10 times of water for the first time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 8 times of water for the second time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 6 times of water for the third time, boiling for 2 hr, decocting with slow fire for 4 hr, mixing decoctions, and filtering with 300-400 mesh filter screen to obtain the final product. Putting the filter screen decoction into a multifunctional traditional Chinese medicine extraction tank, extracting by adopting a steam distillation method, condensing, collecting a distillation stock solution, and filling to obtain the traditional Chinese medicine.
Example 4: a Chinese medicine oral and external use stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation is used as a further scheme of the invention: 180g of seaweed, 160g of dried orange peel, 800mg of cordyceps militaris, 190g of ampelopsis grossedentata tea, 180g of dendrobium, 160g of pummelo peel, 30g of red date, 90g of white poria, 16g of dried pawpaw seed, 15g of dried pineapple flower, 60g of hawthorn, 90g of astragalus, 80g of dried liquorice, 80g of mulberry, 20g of black fungus, 60g of dried ginger, 30g of wormwood and 90g of green tea. Decocting the raw materials in water for four times: adding 10 times of water for the first time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 8 times of water for the second time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 6 times of water for the third time, boiling for 2 hr, and decocting with slow fire for 4 hr; adding 5 times of water for the fourth time, boiling for 1 hr, decocting with slow fire for 4 hr, mixing decoctions, and sieving with 300-mesh 400-mesh filter screen to obtain the final product. Putting the filter screen decoction into a multifunctional traditional Chinese medicine extraction tank, extracting by adopting a steam distillation method, putting Cordyceps militaris and herba Dendrobii powder bags (1 g of Cordyceps militaris and 200g of herba Dendrobii) while decocting, distilling, condensing, collecting distillation stock solution (2 times by distillation method), and filling.
Example 5: a Chinese medicine oral and external use stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation is used as a further scheme of the invention: 180g of seaweed, 180g of dried orange peel, 900mg of cordyceps militaris, 200g of ampelopsis grossedentata tea, 220g of dendrobium, 180g of pummelo peel, 30g of red date, 90g of white poria, 20g of dried pawpaw seed, 20g of dried pineapple flower, 60g of hawthorn, 90g of astragalus, 80g of dried liquorice, 10g of mulberry, 20g of black fungus, 60g of dried ginger, 40g of wormwood and 100g of green tea. Decocting the raw materials in water for four times: adding 10 times of water for the first time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 8 times of water for the second time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 6 times of water for the third time, boiling for 2 hr, and decocting with slow fire for 4 hr; adding 5 times of water for the fourth time, boiling for 1 hr, decocting with slow fire for 4 hr, mixing decoctions, and sieving with 300-mesh 400-mesh filter screen to obtain the final product. Putting the filter screen decoction into a multifunctional traditional Chinese medicine extraction tank, extracting by adopting a steam distillation method, putting Cordyceps militaris and herba Dendrobii powder bags (1.2 g of Cordyceps militaris and 240g of herba Dendrobii) simultaneously, decocting and distilling, condensing, collecting a distillation stock solution (2 times by using a distillation method), and filling to obtain the product.
In the aspect of oral administration:
a Chinese medicinal oral and external stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation, wherein the Chinese medicinal formula of the embodiment 4 is used as a final preferable scheme of the invention.
First, in order to explain the present invention in the aspect of internal administration: the treatment of symptoms caused by metabolic syndrome in human body is described in detail below.
As described in detail below, the invention "example 4" is applied to the internal medicine: the data and the curative effect of treating the symptoms caused by the metabolic syndrome of the human body.
"example 4" of the present invention is in terms of internal medicine: the data and the curative effect for treating the symptoms caused by the metabolic syndrome of the human body are detailed in the table 1.
The diagnosis standard of the metabolic syndrome is based on the diagnosis standard of diabetes mellitus subcontract (CSS) of Chinese medical society: the method comprises the following 3 items or more. 1. Overweight and/or obesity: BMI is more than or equal to 25kg/m 2; 2. blood lipid disorders: the fasting blood TG is more than or equal to 1.7mmol/L, and (or) the fasting blood HDL-C is less than 0.9mmol/L for men or less than 1.0mmol/L for women, (or) the dyslipidaemia is diagnosed; 3. hyperglycemia: FPG is more than or equal to 6.1mmol/L (110mg/dl) and/or 2hPG is more than or equal to 7.8mmol/L (140mg/dl), (or) a person diagnosed as a diabetes treatment; 4. hypertension: SBP/DBP is not less than 140/90mmHg, and/or has been diagnosed as hypertension.
Meets the diagnosis standard of metabolic syndrome, and is between 18 and 70 years old.
Case exclusion criteria: 1. patients under the age of 18 or over the age of 70 years; 2. patients with acute complications of diabetes (including diabetic hypoglycemia, diabetic hyperosmolar coma, diabetic ketoacidosis and ketoacidosis, diabetic lactic acidosis, and diabetic acute infection) in about 1 month; 3. patients with severe center of gravity, liver and renal insufficiency are merged; 4. failure to collaborate with psychotic disorders; 5. pregnant or lactating and pregnant woman preparation 6. who is not concerned (who can not be fasted or can not take traditional Chinese medicine according to the regulation to affect the curative effect); 7. patients with malignant tumor and hematopathy; 8. active tuberculosis patients; 9. ulcerated patients with severe gastrorrhagia; a patient with type I diabetes; type II diabetes mellitus is poorly controlled, in patients requiring insulin injections; 12. the oral antihypertensive drug for primary hypertension is used for poor control and secondary hypertension patients; 13. other cases considered unsuitable by researchers.
A Chinese medicinal composition (oral and topical Chinese medicinal composition) for treating metabolic syndrome, killing bacteria and relieving inflammation, and its application method comprises: the medicine is taken twice daily, and the daily dosage is 1 bottle (30 ml/bottle). When the first morning is empty, preparing half cup of about 80ml of boiled water with the water temperature of about 55-60 ℃, and pouring 15ml of the stock solution for drinking; the second time, half an hour after lunch (the administration method is the same as that of the first time).
Observation indexes are as follows: 1. the therapeutic effect indexes of weight, blood pressure, blood lipid and blood sugar change; 2. the safety indexes include hypoglycemia incidence rate, hunger degree, treatment compliance, liver and kidney functions and blood routine.
Body weight, metabolism, etc., and blood pressure lipid sugar changes are detailed in table 1.
Table 1.
Figure BSA0000184727060000071
A Chinese medicine in the form of oral liquid or liquid for treating the metabolic syndrome, sterilizing and relieving inflammation is disclosed, which is used to treat the symptoms caused by metabolic syndrome and evaluate the comprehensive curative effect.
The oral administration curative effect is as follows: after 20 patients with phlegm-dampness obesity are treated, the average reduction is about 6-8KG, wherein the fat is reduced by about 10%, the bone salt content is increased by about 1KG, the muscle content is increased by about 10KG, the basal metabolic rate is normal, and all 20 cases are effective cases.
The oral administration curative effect also comprises that in 40 cases of patients with blood pressure, blood fat and blood sugar, the first 40 cases are patients with hypertension, blood fat and blood sugar, after treatment, the blood pressure is well controlled, the total cholesterol reaches the triglyceride standard, and the high and low density lipoprotein cholesterol reaches the standard, and all 40 cases are effective cases.
And (3) safety evaluation: the B ultrasonic in 20 patients with phlegm-dampness and obesity suggests that 11 patients have fatty liver with different degrees, wherein 3 patients have an increased transaminase index in the early treatment stage (1 week after the treatment starts) and exceed the normal range, but have no clinical significance, the transaminase is reduced to below the original level at the end of the treatment, and the renal function index and the blood routine examination are not abnormal; among 40 diabetics, 5 patients have self complaints and are easy to have hypoglycemia reaction at ordinary times, but hypoglycemia does not occur in the whole treatment process, 4 patients with normal blood pressure have unobvious blood pressure fluctuation in the treatment process, and the change before and after treatment is not obviously different.
Conclusion of table 1: the medicine is orally taken to treat the symptoms caused by the human metabolic syndrome and has good treatment effect.
External use aspect:
a Chinese medicinal oral and external stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation, wherein the Chinese medicinal formula of the embodiment 4 is used as a final preferable scheme of the invention.
Secondly, in order to explain the invention, in the aspect of external application, the invention provides a method for treating relevant symptoms such as sterilization and anti-inflammation of mice, and the experimental data and effects of the invention are described in detail below.
The following examples are intended to further illustrate the present invention, but should not be construed as limitations or restrictions on the present invention, and unless otherwise specified, features used in the examples may be replaced by other features having equivalent functions or effects without departing from the inventive concept, and other features known in the art.
Examples 1-5 preliminary screening of stock solutions of herbal preparations, wherein "example" is a normally bred mouse. Experimental animals: the method is characterized in that healthy male Kunming mice of 30-35 days old are selected, 20 mice are used in each group, and each group is measured according to indexes of interleukin-2 (interleukin-2 kit Beijing Jingjinmei entity engineering Co., Ltd.), tumor necrosis factor-a (tumor necrosis factor-a kit Eboantibody (Shanghai) trade Co., Ltd.), gamma interferon (swelling gamma interferon kit Shanghai Zhen Shi Shuang Co., Ltd.), staphylococcus aureus, escherichia coli, salmonella gallinarum, proteus and salmonella murinus, so that the embodiment 4 of the invention can better diminish inflammation, kill or inhibit various bacteria.
In some embodiments, the dosage form is a herbal stock solution mixture.
Aiming at the matching of each group of traditional Chinese medicine stock solution mixture and each microorganism, two identical plate culture dishes are taken, and 1, before the anti-inflammatory drug experiment, the anti-inflammatory drug promotes the body to recover health: culturing strain of mouse injury with liquid LB to multiply amplify recipient strain, taking 20 mice each, and inoculating 0.1mL (about 5 million virus particle bacteria) subcutaneously for each mouse; 2. before the experiment of the bactericidal medicine, the function is to kill the corresponding pathogenic microorganisms in the animal body: solid LB culture rat wound strains, implanted about per ml containing ten eight times of bacteria. The control group is a common solid LB culture medium, 1ml of the stock solution of the traditional Chinese medicine composition is added into the molten LB culture used by the test group, and the solid LB culture medium is formed after uniform mixing and cooling. To this group of LB medium plates, 0.1mL of bacteria each having a concentration of about 5 million virus particles (7 th power/mL of 10) was added dropwise and cultured under the same condition F37C for 24 hours. Calculating the number of colonies in the LB plate without the traditional Chinese medicine composition as Nc, the number of colonies in the LB plate with the traditional Chinese medicine composition as Nt, the bacteriostasis rate as n, and wiping the wound of the mouse if n ═ Nc-Nt/Nc ] X100%.
The traditional Chinese medicine stock solution mixture composition provided by the invention can inhibit the application of interleukin-2, tumor necrosis factor-a and gamma interferon in medicines for treating, preventing or improving diseases caused by bacteria.
The traditional Chinese medicine stock solution mixture composition provided by the invention is used in medicines for treating, preventing or improving diseases caused by staphylococcus aureus, escherichia coli, salmonella gallinarum, proteus and salmonella murinus.
The traditional Chinese medicines of the invention are used for preparing a stock solution mixture composition. 1. In the aspect of anti-inflammation, the concentration of interleukin-2, tumor necrosis factor-a and gamma interferon in a mouse body can be effectively inhibited, and various bacteria can be killed or inhibited; 2. in the aspect of inhibiting or killing bacteria, at least five bacteria can be effectively inhibited or killed against staphylococcus aureus, escherichia coli, salmonella gallinarum, proteus vulgaris and salmonella murinus.
The relevant test data are detailed in table 2.
Table 2.
Figure BSA0000184727060000081
Figure BSA0000184727060000091
Conclusion of table 2: a Chinese medicinal oral and external stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation, which is used for evaluating the treatment effect of a mouse sterilization experiment: the composition can effectively inhibit the concentrations of IL-2, TNF-a and IFN-Y in mice and kill or inhibit various bacteria, so that the composition can be used as a traditional Chinese medicine composition with sterilization and anti-inflammation effects.
A Chinese medicinal oral administration and external use stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation, the Chinese medicinal stock solution mixture has definite curative effect, is taken orally, and has no toxic or side effect; it is applied externally and has no damage to skin.
1. The oral administration can treat the symptoms caused by human metabolic syndrome without side effect.
Oral administration: treating phlegm dampness obesity, insomnia, alopecia, edema, gastritis, diabetes, hypertension, hyperglycemia, hyperlipidemia, gout, tumor, numbness, vertigo, halitosis, constipation, etc. caused by metabolism syndrome disorder.
2. The external use has the functions of sterilization, inflammation diminishing, sterilization, itching relieving and swelling diminishing, and has no harm to the skin of a human body.
External use: has antibacterial, antiinflammatory, antipruritic, and repercussive effects, and is suitable for treating corner ulcer, oral ulcer, toothache, acne, nasopharyngitis, pruritus, wound inflammation, paronychia, onychomycosis, tinea pedis, bromhidrosis, foot odor, and hemorrhoid.
The above embodiments are preferred embodiments of the present invention, but the embodiments of the present invention are not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention are intended to be included in the scope of the present invention.

Claims (7)

1. The invention relates to a traditional Chinese medicine prepared stock solution mixture for oral administration and external use for treating human metabolic syndrome and sterilizing and diminishing inflammation, which has the following curative effects: the traditional Chinese medicine raw liquid mixture has definite curative effect, is taken orally and has no toxic or side effect; it is applied externally and has no damage to skin.
2. The parts are mass parts, and are microgram, milligram, gram, kilogram and other mass units commonly used in the field.
3. A Chinese medicinal oral and topical stock solution mixture for treating metabolic syndrome and resisting bacteria and inflammation is provided. The technical scheme of the formula adopted by the invention is as follows: the tea is prepared from the following raw materials of dried pineapple flowers, dried pawpaw seeds, mulberry, black fungus, seaweed, astragalus mongholicus, dried liquorice, white poria, dried orange peel, cordyceps militaris, pummelo peel, red dates, hawthorn, dried ginger, maoyanmei tea, wormwood, green tea and dendrobium by mass: 320 parts of seaweed 180-.
4. A Chinese medicinal oral and topical stock solution mixture for treating metabolic syndrome and resisting bacteria and inflammation is provided. The preferable formula is synthesized, and specifically: 180g of seaweed, 160g of dried orange peel, 800mg of cordyceps militaris, 190g of ampelopsis grossedentata tea, 180g of dendrobium, 160g of pummelo peel, 30g of red date, 90g of white poria, 16g of dried pawpaw seed, 15g of dried pineapple flower, 60g of hawthorn, 90g of astragalus, 80g of dried liquorice, 80g of mulberry, 20g of black fungus, 60g of dried ginger, 30g of wormwood and 90g of green tea.
5. A Chinese medicinal oral and topical stock solution mixture for treating human metabolic syndrome and resisting bacteria and inflammation is prepared by: decocting the raw materials in water for four times: adding 10 times of water for the first time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 8 times of water for the second time, boiling for 2 hours, and decocting with slow fire for 4 hours; adding 6 times of water for the third time, boiling for 2 hr, and decocting with slow fire for 4 hr; adding 5 times of water for the fourth time, boiling for 1 hr, decocting with slow fire for 4 hr, mixing decoctions, and sieving with 300-mesh 400-mesh filter screen to obtain the final product. Putting the filter screen decoction into a multifunctional traditional Chinese medicine extraction tank, extracting by adopting a steam distillation method, putting Cordyceps militaris and herba Dendrobii powder bags (1 g of Cordyceps militaris and 200g of herba Dendrobii) while decocting, distilling, condensing, collecting distillation stock solution (2 times by distillation method), and filling.
6. The invention relates to a traditional Chinese medicine oral and external stock solution mixture for treating human metabolic syndrome and sterilizing and diminishing inflammation, which has the following oral and external curative effects:
1. the oral administration can treat the symptoms caused by human metabolic syndrome without side effect. Oral administration: treating phlegm dampness obesity, insomnia, alopecia, edema, gastritis, diabetes, hypertension, hyperglycemia, hyperlipidemia, gout, tumor, numbness, vertigo, halitosis, constipation, etc. caused by metabolism syndrome disorder.
2. The external use has the functions of sterilization, inflammation diminishing, sterilization, itching relieving and swelling diminishing, and has no harm to the skin of a human body.
External use: has antibacterial, antiinflammatory, antipruritic, and repercussive effects, and is suitable for treating corner ulcer, oral ulcer, toothache, acne, nasopharyngitis, pruritus, wound inflammation, paronychia, onychomycosis, tinea pedis, bromhidrosis, foot odor, and hemorrhoid.
7. A Chinese medicinal oral and topical stock solution mixture for treating human metabolic syndrome and resisting bacteria and inflammation, its application method comprises: 1. the oral administration is carried out, the daily dose is 30ml, the oral administration is carried out for 2 times, specifically 15ml (1/3 cups of about 80ml boiled water with water temperature of 50-60 ℃) is taken once in each morning on an empty stomach and half an hour after lunch, the oral administration has the curative effect, 20 days is a course of treatment, the effect is usually achieved within one week, and the cure can be realized in one to two courses of treatment; 2. the external application can be applied for multiple times according to actual requirements, has the effects of sterilizing and diminishing inflammation, relieving itching and reducing swelling for external application, and can be cured within one day and three to five days.
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