CN108452225A - A kind of Chinese medicine for treating pulmonary tuberculosis - Google Patents

Abstract

The present invention relates to a kind of Chinese medicines for treating pulmonary tuberculosis, it is prepared by the raw medicinal material of following weight proportion：10 parts of the tuber of stemona, 5 parts of bletilla, 10 parts of the root of purple-flowered peucedanum, 15 parts of humulus grass, 6 parts of bark of ash, 10 parts of the root bark of Chinese wolf-berry.Clinical experiments have proved that the present invention can safely and effectively treat pulmonary tuberculosis.

Description

A kind of Chinese medicine for treating pulmonary tuberculosis

Technical field

The present invention relates to a kind of Chinese medicines, and in particular to a kind of Chinese medicine for treating pulmonary tuberculosis.

Background technology

Tuberculosis is the chronic infectious disease caused by mycobacterium tuberculosis infection.Tulase may invade the various devices of Whole Body Official, but mainly invade lungs, referred to as pulmonary tuberculosis.Excreter is its important infection sources.After human infection tulase not necessarily Morbidity is likely to cause clinical onset when resistance reduces or cell-mediated allergy increases.Clinical manifestation be have compared with Close tuberculosis contact history, onset can suddenly be delayed, mostly low-heat（Afternoon is to write）, night sweat, it is weak, receive it is poor, become thin, Nv Xingyue Through imbalance etc.；Respiratory symptom has cough, expectoration, spitting of blood, pectoralgia, uncomfortable in chest in various degree or expiratory dyspnea.

Pulmonary tuberculosis is the incidental a kind of chronic and deferred infectious disease of young people.It can fall ill throughout the year, 15 years old to 35 years old teenager is age peak year occurred frequently of pulmonary tuberculosis.4~8 weeks incubation periods.Wherein 80% is happened at lung, other Position（Neck lymph, meninx, peritonaeum, intestines, skin, bone）It also can secondary infection.Interpersonal respiratory infectious is that this disease passes The major way of dye.The infection sources is the consumptive for contacting discharge of bacteria.With the propagation of environmental pollution and AIDS, tuberculosis Incidence is more strong.

The pathogenic bacteria tulase of pulmonary tuberculosis belongs to Actinomycetal, easily forms drug-fast bacteria, is formed centainly to antibiosis extract for treating Difficulty.Western medicine has isoniazid, rifampin, ethambutol, pyrazinamide, streptomysin etc. at present, but its therapeutic effect is equal Undesirable and side effect is larger.

This disease is according to its clinical manifestation category Chinese medicine " consumptive disease illness ", " tuberculosis " scope.

Medicinal material present Research involved in the present invention is as follows：

The tuber of stemona【Source】This product is the root of Stemonaceae plant radix stemonae sessilifoliae, Radix stemonae japonicae and radix stemonae tuberosae.It is withered in winter overground part After withering or before spring rudiment, lifted root, remove radicula, soil, in boiling water just it is well-done when, taking-up dry or dry.【Property Taste】It is sweet, bitter, tepor.【Channel tropism】It is distributed in lung channel.【Major function】It moistens the lung and relieve the cough, desinsection and delousion.Main new chronic cough is coughed, tuberculosis, and hundred Day cough；Enterobiasis, body louse, tinea scabies.【Usage and dosage】 3~10g.【Pay attention to】Taste have hot person to use with caution.

Bletilla【Source】This product is the rhizome of orchid bletilla.Excavating the 9-10 months after plantation 3-4, rhizome is soaked About 1h or so in water cleans soil, removes branch fibrous root, is taken out when through boiling to inner face without the white heart, shines or a heatable brick bed is not glued to surface is stiff When knot, after smoking for 1 night with Sulfur, dries or a heatable brick bed is dry, then hit residual palpus, make surface at bright and clean yellowish white, weed out impurity.【Property Taste】It is bitter, sweet, puckery, it trembles with fear.【Channel tropism】It attaches to the lung and stomach meridians.【Major function】Astringing to arrest bleeding, detumescence and promoting granulation.Main spitting of blood is spitted blood, nosebleed Blood is had blood in stool, traumatic hemorrhage；Ulcerative carbuncle pyogenic infections；It scalds and burns, rhagadia manus et pedis, anal fissure.【Usage and dosage】 3~10g.

The root of purple-flowered peucedanum【Source】This product is the root of samphire RADIX PEUCEDANI and RADIX PEUCEDANI.Autumn, winter take root, remove The aerial stem of plant and soil are removed, is dried.【Nature and flavor】It is bitter, pungent, it is slightly cold.【Channel tropism】Return lung, spleen, Liver Channel.【Major function】Evacuate wind Heat, lowering the adverse-rising QI to resolve phlegm.Main affection of exogenous wind-heat, lung heat phlegm are strongly fragrant；Cough and phlegm, yellow and sticky sputum；Inverse deficiency of food, chest and diaphragm expire vexed.【Usage is used Amount】 5~10g.

Humulus grass【Source】This product is the herb of moraceae plants humulus grass.9~October harvests, and selects fine day, gathers in aerial part, Impurity is removed, is dried.【Nature and flavor】It is sweet, bitter, it trembles with fear.【Channel tropism】Return lung, kidney channel.【Major function】Clearing heat and detoxicating, inducing diuresis for treating strangurtia. Main cough with lung heat, lung carbuncle；Abnormal heat polydipsia, heat gonorrhea, oedema, difficult urination, damp-heat dysentery；Pathopyretic ulcer, pruitus.【Usage Dosage】 10~15g.

Bark of ash【Source】This product is the root of gentianaceae plant bark of ash, gentiana crassicaulis Duthie, gentiana straminea, Da Wuli bark of ash.Autumn digs After root, directly dry.【Nature and flavor】It is bitter, pungent, it is slightly cold.【Channel tropism】Return stomach, liver, gallbladder channel.【Major function】Wind-damp dispelling, relaxing muscles and tendons network, Clearind deficient heat, removing dampness through diuresis and removing jaundice.The logical pain of main rheumatism numbness, muscles and bones contraction, hands and feet caused by paralysis；Osteopyrexia and fever, children's infantile malnutrition due to digestive disturbances or intestinalparasites heat, jaundice with damp-heat pathogen.【With Method dosage】 5~10g.

The root bark of Chinese wolf-berry【Source】This product is the root skin of matrimony vine of solanaceae plant.Early spring, late fall excavate root, clean soil, strip Skin zone dries.【Nature and flavor】It is sweet, it trembles with fear.【Channel tropism】Return lung, kidney channel.【Major function】Clearind deficient heat, purte the white, cool blood.Main deficiency of Yin labor Heat, hectic fever due to yin night sweat；Infantile malnutrition generates heat, dyspnea and cough due to lung-heat；It spits blood, bleeding from five sense organs or subcutaneous tissue, hematuria；It quenches one's thirst.【Usage and dosage】 9~15g.

Invention content

The present invention is intended to provide a kind of Chinese medicine for treating pulmonary tuberculosis, by selecting suitable medicinal material and its proportioning, Achieve the purpose that safely and effectively to cure pulmonary tuberculosis.

In order to achieve the above object, the present invention uses following technical scheme：

It is a kind of for treating the Chinese medicine of pulmonary tuberculosis, which is characterized in that it be prepared by the raw medicinal material of following weight proportion and At：10 parts of the tuber of stemona, 5 parts of bletilla, 10 parts of the root of purple-flowered peucedanum, 15 parts of humulus grass, 6 parts of bark of ash, 10 parts of the root bark of Chinese wolf-berry.

Inventor thinks the pulmonary tuberculosis cause of disease nothing more than two aspects of endexoteric, and external cause is infection, and internal cause is qi and blood Two is empty, cloudy essence consume.Physically weak not multiple because healthy tendency is first hindered, then consumptive disease worm, which is taken advantage of a weak point in opponent's defence, invades, consumptive disease worm-eaten lung, lack of lung-YIN, heat impairing pulmonary collateral Then see dry cough, spitting of blood, swallow the diseases such as dry.The deficiency syndrome of the lung is unable to transporation of body fluid, and kidney loses the source of money life, then sick and in kidney, the deficiency of the kidney yin, the fire of deficiency type Disturbance, then be shown in osteopyrexia and fever, and man's nocturnal emission, woman's amenorrhoea, very then kidney-KIN being deficient, hyperactivity of heart-liver fire above walk what lung, more to disappearing Burn lung yin, then sees that night sweat is insomnia, the kind anger of agitation, the diseases such as pain in chest and hypochondrium.The deficiency syndrome of the lung consumes the autotrophy for taking mother-qi by force again, then disease and in spleen, Deficiency of the spleen causing weakness of QI, and see shortness of breath, it is weak, receive less, the diseases such as loose stool.In short, this disease begins to be mostly consumption of yin-fluid, disease is lung, after then cloudy The fire of deficiency type is prosperous, and lung kidney is with disease or deficiency of both qi and yin, and lung spleen is the same as disease.Treatment should be supported lung with enriching yin, be replenished qi to invigorate the spleen, help essence and blood, heat-clearing drop Fiery, relieving cough and reducing sputum is basic, therefore assembles we.

The beneficial effects of the present invention will now be described with reference to clinical experimental data：

1, general information

Outpatient service and Mycobacterium tuberculosis in hospitalized tuberculosis patient 89 are collected in inventor in October, 2010 ~ 2013 year altogether between June, are randomly divided into treatment Group 45 and control group 44, treatment group man 33, female 22,43~81 years old age, average age 46 years old, the course of disease 1~3 year； Control group man 28, female 16,40~80 years old age, average age 48 years old, the course of disease 1~3 year.2 groups of genders, age and course of disease ratio Compared with no significant difference, it is comparable.

Diagnostic criteria

Diagnostic criteria according to diagnosis of pulmonary tuberculosis and treatment guidelines：1）Cough, expectoration three weeks or more, can with spitting of blood, pectoralgia, The symptoms such as expiratory dyspnea；2）It generates heat (Chang Wuhou low-heat), it can be with night sweat, weak, appetite reduction, weight loss, menstrual disorder；3） Allergic manifestation caused by tuberculosis allergy：Erythema nodosum, phlycenular conjunctivitis and tuberculosis rheumatism etc.；4）Tuberculin (P PD C5TU) Skin-test：Indicate that body is in super allergic state when strong positive is presented, morbidity risk rate is high, can be used as Clinical diagnosis is lungy to refer to indication；5）When hectic, the normal unobvious of physical signs of lung；Pulmonary lesion can have phase when wide Sign is answered, audible and middle fine bubbling rale when having apparent cavity or concurrent bronchiectasis；Kang Nixia, which reduces prompt apex pulmonis, lesion.

2, test method

2.1 therapy

The oral present invention for the treatment of group is according to decoction made from specific embodiment 1,3 times a day.The course for the treatment of 8 weeks.

Control group takes orally isoniazid tablets, is taken according to its specification.The course for the treatment of 8 weeks.

3, criterion of therapeutical effect and treatment results

3.1 criterion of therapeutical effect

It cures：Lung is absorbed with bone tuberculosis imageological examination prompt pathological tissues shade or calcification, pulmonary tuberculosis Sputum inspection（-）, knot Nuclearity meningitis and intestinal tuberculosis blood test prompt erythrocyte sedimentation rate, TB-Ab are changed into normally, hepatic lesion patient, liver function check Normally, patient clinical symptom disappears, and constitution is restored；

It is effective：Patient clinical symptom makes moderate progress, and appetite increases, no night sweat hectic fever, and constitution improves；

In vain：Through treating patient clinical symptom without improvement.

3.2 treatment results are shown in Table 1.

1 two groups of curative effects of table compare

Group	n	Recovery from illness	It is effective	In vain	Total effective rate (%)	Serious adverse reaction example
							Treatment group	45	26	12	7	84.4%	0
Control group	44	23	10	11	75.0%	0

As it can be seen that drug produced by the present invention can safely and effectively treat pulmonary tuberculosis, there is promotional value.

Specific implementation mode

In order to better understand with the implementation present invention, further illustrated the present invention with reference to specific embodiment.

Specific embodiment 1

It weighs：10 grams of the tuber of stemona, 5 grams of bletilla, 10 grams of the root of purple-flowered peucedanum, 15 grams of humulus grass, 6 grams of bark of ash, 10 grams of the root bark of Chinese wolf-berry；Add 8 times of amount water, decocts 1.5 hours, filtering；Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate, be concentrated into 120 grams to get meet normally at The decoction of one day dosage of people.

For treating pulmonary tuberculosis.It is oral, it is taken three times in the morning, afternoon and evening per bu.

Specific embodiment 2

It weighs：10 grams of the tuber of stemona, 5 grams of bletilla, 10 grams of the root of purple-flowered peucedanum, 15 grams of humulus grass, 6 grams of bark of ash, 10 grams of the root bark of Chinese wolf-berry；Add 10 times of amount water, decocts It boils 2 hours, filters；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate concentrates, dry, packs to get meeting The powder of one day dosage of normal adult.

For treating pulmonary tuberculosis.It is oral, daily once.

Specific embodiment 3

It weighs：10 grams of the tuber of stemona, 5 grams of bletilla, 10 grams of the root of purple-flowered peucedanum, 15 grams of humulus grass, 6 grams of bark of ash, 10 grams of the root bark of Chinese wolf-berry；Add 6 times of amount water, decocts It 3 times, decocts 1 hour every time, merges decoction liquor, concentrate, it is dry, capsule shells are packed into get one day dosage of normal adult is met Capsule.

For treating pulmonary tuberculosis.It is oral, it is taken twice sooner or later per bu.

Claims (4)

1. a kind of Chinese medicine for treating pulmonary tuberculosis, which is characterized in that it is prepared by the raw medicinal material of following weight proportion It forms：10 parts of the tuber of stemona, 5 parts of bletilla, 10 parts of the root of purple-flowered peucedanum, 15 parts of humulus grass, 6 parts of bark of ash, 10 parts of the root bark of Chinese wolf-berry.

2. the Chinese medicine for treating pulmonary tuberculosis as described in claim 1, which is characterized in that preparation method is：It weighs：Hundred 10 parts of portion, 5 parts of bletilla, 10 parts of the root of purple-flowered peucedanum, 15 parts of humulus grass, 6 parts of bark of ash, 10 parts of the root bark of Chinese wolf-berry；Add 8 times of amount water, decocts 1.5 hours, mistake Filter；Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate is concentrated into 120 parts to get decoction；Above-mentioned part each means weight Measure part.

3. the Chinese medicine for treating pulmonary tuberculosis as described in claim 1, which is characterized in that preparation method is：It weighs：Hundred 10 parts of portion, 5 parts of bletilla, 10 parts of the root of purple-flowered peucedanum, 15 parts of humulus grass, 6 parts of bark of ash, 10 parts of the root bark of Chinese wolf-berry；Add 10 times of amount water, decocts 2 hours, mistake Filter；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate concentrates, dry, packs to get powder；Above-mentioned part is Refer to parts by weight.

4. the Chinese medicine for treating pulmonary tuberculosis as described in claim 1, which is characterized in that preparation method is：It weighs：Hundred 10 parts of portion, 5 parts of bletilla, 10 parts of the root of purple-flowered peucedanum, 15 parts of humulus grass, 6 parts of bark of ash, 10 parts of the root bark of Chinese wolf-berry；Add 6 times of amount water, decocts 3 times, decoct every time It boils 1 hour, merges decoction liquor, concentrate, it is dry, capsule shells are packed into get capsule；Above-mentioned part each means parts by weight.