CN104706998A - Traditional Chinese medicine spray for treating allergic rhinitis in clinical care and preparation method thereof - Google Patents
Traditional Chinese medicine spray for treating allergic rhinitis in clinical care and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine spray for treating allergic rhinitis in clinical care. The traditional Chinese medicine spray is prepared from the following main raw materials in parts by weight: 10-20 parts of lonicera japonica, 3-9 parts of calamine, 3-10 parts of wrinkled gianthyssop herb, 6-12 parts of flos chrysanthemi indici, 3-9 parts of lalang grass rhizome, 3-10 parts of herba violae, 5-10 parts of acorus calamus, 10-30 parts of flos sophorae, 3-6 parts of Japanese thirstle root, 15-20 parts of herba centellae, 10-30 parts of radix angelicae pubescentis and 4-7 parts of medical stone. Based on the principle of treating allergic rhinitis by Chinese medics and Chinese medicines, the herbs are selected to prepare the traditional Chinese medicine spray which can directly act on affected parts to quickly prevent rhinocnesmus and rhinorrhea, so that more comprehensive treatment is realized. The traditional Chinese medicine spray for treating allergic rhinitis in clinical care mainly aims to clear away heat and toxic materials so as to quickly treat allergic rhinitis, and has an extremely good treating effect on allergic rhinitis.
Description
Technical field
The invention discloses a kind of Traditional Chinese medicinal spray, especially relate to Traditional Chinese medicinal spray of a kind of clinical care treatment of allergic rhinitis and preparation method thereof, belong to traditional Chinese medicine field.
Background technology
Allergic rhinitis and allergic rhinitis, after referring to atopic individuals contact allergen, primarily of medium (mainly histamine) release of IgE mediation, and have the nasal mucosa non-infectious inflammatory disease that panimmunity competent cell and cytokine etc. participate in.Its essential condition occurred has 3: namely specific antigen causes the material of organism immune response; Atopic individuals and so-called individual variation, allergic constitution; Specific antigen and spy answer both type individualities to meet.Allergic rhinitis are global health problem, can cause numerous disease and disability.
The cause of disease: allergic rhinitis are a kind of multi-factor diseases being interacted by gene and environment and brought out.The risk factor of allergic rhinitis may be present in all age brackets.1. inherited pathogenic factor: allergic rhinitis patients has atopy body constitution, usually demonstrates familial aggregation, studies have found that some gene is associated with allergic rhinitis.2. allergen exposes: allergen is inducing specific IgE antibody and the antigen reacted with it.Their multi-sources are in animal, plant, insecticide, fungus or occupational material.Its composition is protein or glycoprotein, and only a few is polysaccharide.Allergen is mainly divided into inhalant allergen and food-consuming structure.Inhalant allergen is the main cause of allergic rhinitis.(1) demodicid mite is dermatophagoides pteronyssinus, dust mite etc. the topmost demodicid mite in subtropical zone and torrid areas.Dermatophagoides pteronyssinus, and mainly to be lived at the bottom of mattress, bed, in medicated pillow, carpet, furniture and push toy for food with mankind's scurf.Breed the fastest in the environment of moist (relative humidity is greater than 80%) in heat (more than 20 DEG C).Dermatophagoides pteronyssinus allergen is included in its fecal pellets, and after the fabric be infected with is touched, these granules are just exposed in air and also can again deposit very soon.Mite allergen concentration in air is relevant with the morbidity of allergic rhinitis.(2) pollen anemophilous pollen is huge and can long-distance transmissions due to the amount of flying away, and thus can affect the crowd away from pollen source several hundred kilometers.Entomophila pollen only has directly contact just meeting sensitization, as agronomist and florist's shop salesman.The sensitizability of pollen changes with season, geographical position, temperature and floristics.Most of pollen sensitization person can suffer from conjunctivitis.(3) scurf of animal scurf animal and secretions carry sensitinogen.Cat, Canis familiaris L. allergen extensively exist in indoor dust and furniture decoration.(4) fungus allergen mycete discharges allergenicity spore in the environment of indoor and outdoor, and hygrothermal environment growth rapidly.(5) cockroach allergens allergen sees in its feces and carapace, and granule is comparatively large, does not send out in atmosphere.(6) food allergens is when allergic rhinitis are without other system symptom, and food allergy is rare.On the other hand, when the multiple organ of patient is got involved, food allergy is common.Concerning baby, majority is caused by milk and Semen sojae atricolor; Concerning adult common food allergen comprise: Semen arachidis hypogaeae, nut, fish, egg, milk Semen sojae atricolor, Fructus Mali pumilae, pears etc.
Clinical manifestation: classical symptom mainly paroxysmal sneeze, clear water sample nasal mucus, nasal obstruction and the rhinocnesmus of allergic rhinitis.Part is with hyposmia.1. sneeze: for several times paroxysmal outbreak every day, at every turn more than 3, how morning rise or night or contact allergy former after show effect at once.2. thin nasal discharge: a large amount of clear water sample nasal mucus, can not consciously drip from nostril sometimes.3. have a stuffy nose: interval or lasting, one-sided or bilateral, light and heavy degree differs.4. rhinocnesmus: Most patients intranasal is itched, pollinosis patient can accompany ophthalmic pruritus, itching in the ear and itching throat.
The Chinese patent of Authorization Notice No. CN 102641394 B (application number 201210138487.0) discloses a kind of Chinese medicine composition for the treatment of of allergic rhinitis, it is characterized in that it is made up of following raw material medicaments: Flos Magnoliae 20-40 part, Semen Lepidii (Semen Descurainiae) 20-40 part, Gecko 10-30 part, Periostracum Cicadae 10-30 part, Semen Arecae 10-30 part, Fructus Chebulae 10-20 part, Herba Boenninghauseniae 10-20 part, Oletum Trogopterori 10-20 part, Flos Caryophylli 8-15 part, Radix Astragali 8-15 part.The Chinese medicine that patent discloses a kind for the treatment of of allergic rhinitis of Authorization Notice No. CN 102552750 B (application number 201210085822.5), it is characterized in that, its crude drug is made up of the medical material of following weight portion: Rhizoma Phragmitis 30-50 part, Semen Coicis 30-50 part, Semen Benincasae 10-20 part, Semen Persicae 10-20 part, Flos Mume 30-50 part, Flos Lonicerae 10-20 part, Gypsum Fibrosum 10-20 part.
As can be seen here, Chinese medicine occupies very important status in treatment of allergic rhinitis, but in existing patent, great majority are oral liquids, and its onset is slow, can not antipruritic, fluid stopping nasal mucus fast for the serious patient of allergic rhinitis.
Summary of the invention
For the present situation of the means deficiency of existing treatment of allergic rhinitis, an object of the present invention is the Traditional Chinese medicinal spray providing clinical care treatment of allergic rhinitis, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Traditional Chinese medicinal spray.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 10-20 part, Calamina 3-9 part, Herba Pogostemonis 3-10 part, Flos Chrysanthemi Indici 6-12 part, Rhizoma Imperatae 3-9 part, Herba Violae 3-10 part, Rhizoma Acori Graminei 5-10 part, Flos Sophorae 10-30 part, cirsii japonici,radix 3-6 part, Herba Centellae 15-20 part, Radix Angelicae Pubescentis 10-30 part, Maifanitum 4-7 part.
The Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 12-18 part, Calamina 4-7 part, Herba Pogostemonis 5-8 part, Flos Chrysanthemi Indici 8-10 part, Rhizoma Imperatae 4-6 part, Herba Violae 5-8 part, Rhizoma Acori Graminei 6-8 part, Flos Sophorae 12-20 part, cirsii japonici,radix 4-5 part, Herba Centellae 16-19 part, Radix Angelicae Pubescentis 15-25 part, Maifanitum 18-25 part.
The Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Flos Lonicerae 15 parts, Calamina 6 parts, Herba Pogostemonis 6 parts, Flos Chrysanthemi Indici 9 parts, Rhizoma Imperatae 5 parts, Herba Violae 6 parts, Rhizoma Acori Graminei 7 parts, 15 parts, Flos Sophorae, cirsii japonici,radix 4.5 parts, Herba Centellae 17 parts, Radix Angelicae Pubescentis 20 parts, Maifanitum 6 parts.
The preparation method of above-mentioned Traditional Chinese medicinal spray, preparation process is as follows:
1. get clean Calamina and Maifanitum, smash, put in crucible, be fired to micro-red in smokeless stove fire, take out, pour leaching in basin immediately into and quench, stir, incline and suspension, rock ballast is dried, then calcine 2-6 time, finally rock ballast is discarded.Get suspension clarification, pour clear water into, by the fine powder drying for standby leached;
2. Herba Pogostemonis and Flos Chrysanthemi Indici are placed in preheated container, fry with moderate heat and take out to surperficial buff, grind to form last for subsequent use;
3. by Rhizoma Imperatae and cirsii japonici,radix clean water 3-7 time, be placed on preheated iron plate, repeatedly smoke 20-40 minute, cool that to grind to form smalls stand-by;
4. Rhizoma Acori Graminei and Herba Centellae cleaned and drain away the water, get proper amount of edible oil and be placed in the Rhizoma Acori Graminei and Herba Centellae of to put into when surrounding is smoldered in pot in pot and draining away the water, micro-stir-fry, to buff, takes out that to grind to form smalls stand-by;
5. be layered on food steamer by Flos Lonicerae, Herba Violae, Flos Sophorae and Radix Angelicae Pubescentis mixing, yellow wine sprinklings in, slightly stewing 10-30 minute, little fire steams out blue or green taste, again evenly sprays yellow wine, steams 30-50 minute, taking-up baking 1-2 hour, and it is stand-by to grind to form smalls;
6. step 1.-5. gained crude drug mixing, add ethanol, and decoct twice, first time adds raw material gross weight 2-4 ethanol doubly, and little fire simmers 20-40 minute slowly, and ceaselessly stirs, filter, obtain filtrate 1, second time adds raw material gross weight 1-3 ethanol doubly, big fire is heated to boiling, changes little fire and decocts 10-20 minute, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, must filtrate be mixed, after mixing filtrate being heated to boiling, leave standstill 10-20 hour, get supernatant loading air-tight bottle and namely obtain Traditional Chinese medicinal spray.
The preparation method of above-mentioned Traditional Chinese medicinal spray, 1. rock ballast dries by step, then calcines 3-5 time (preferred, to be dried by rock ballast, then calcine 4 times).
The preparation method of above-mentioned Traditional Chinese medicinal spray, step is 3. by Rhizoma Imperatae and cirsii japonici,radix clean water 4-6 time, be placed on preheated iron plate, repeatedly smoke 25-35 minute (preferably, by Rhizoma Imperatae and cirsii japonici,radix clean water 5 times, be placed on preheated iron plate, repeatedly smoke 30 minutes).
The preparation method of above-mentioned Traditional Chinese medicinal spray, 5. step sprays yellow wine, slightly stewing 15-25 minute (preferred, yellow wine in sprinkling, slightly stewing 20 minutes).
The preparation method of above-mentioned Traditional Chinese medicinal spray, 5. step evenly sprays yellow wine again, steams 35-45 minute, takes out and dries 1.3-1.8 hour (preferred, again evenly to spray yellow wine, steam 40 minutes, take out baking 1.5 hours).
The preparation method of above-mentioned Traditional Chinese medicinal spray, 6. first time adds raw material gross weight 2.5-3.5 ethanol doubly to step, and little fire is simmered 25-35 minute (preferred, add the ethanol of raw material gross weight 3 times for the first time, little fire simmers 30 minutes slowly) slowly.
The preparation method of above-mentioned Traditional Chinese medicinal spray, step 6. second time adds raw material gross weight 1.5-2.5 ethanol doubly, and big fire is heated to boiling, change little fire and decoct 13-18 minute (preferably, second time adds the ethanol of raw material gross weight 2 times, and big fire is heated to boiling, changes little fire and decocts 15 minutes).
Using method: for making the present invention reach optimum therapeuticing effect, gets Traditional Chinese medicinal spray 1-3ml of the present invention at every turn, is sprayed on nasal cavity, and one for several times.
This Chinese medicine composition, to rhinitis Be very effective, not only has effect of stuffy nose relieving, can also effect a radical cure the disease of rhinitis, and this Chinese medicine composition also has effect of removing toxic substances, blood stasis dispelling simultaneously, causes lethargy for prolonged illness, and look tired person has good medical treatment effect.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient, the general disposable solution of Traditional Chinese medicinal spray of the present invention, recurrent is low.General use obviously took effect the same day, adhered to that medication 7 days patients can fully recover substantially.The local common medical material of multiselect of the present invention, the local common medical material of price multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Flos Lonicerae: Flos Lonicerae is just extensive and famous with its medical value since ancient times.Its effect mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.Sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Calamina: this product character is block aggregation, in irregular bulk, canescence or pale red.Surface mealiness, matt, uneven, porous, like cellular.Body is light, frangible.Odorless, taste is micro-puckery.Function cures mainly: removing toxic substances improving acuity of vision and removing nebula, the antipruritic sore of removing dampness.For conjunctival congestion and swelling pain, marginal blepharitis, nebula film bulbar conjunctiva polyp, ulcer being unable to heal, pus is dripping, eczema, skin pruritus.
Herba Pogostemonis: acrid in the mouth, warm in nature.Gui Jing: return spleen, stomach, lung meridian.Effect: removing dampness is amusing, ward off dirty and in, expelling summer-heat, delivers.Cure mainly: for dampness taste, distension and fullness in the abdomen, hygropyrexia from the beginning of, vomit, have loose bowels, the disease such as heat-damp in summer, fever with chills, fever with aversion to cold, chest distress.
Flos Chrysanthemi Indici: the leaf of Herba Dendranthematis indici, flower and all herbal medicine.Bitter in the mouth, pungent, cool, heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, dissipating blood stasis, improving eyesight, blood pressure lowering.Prevent and treat epidemic cerebrospinal meningitis, prevention influenza, flu, treatment hypertension, hepatitis, dysentery, carbuncle furuncle treatment skin ulcer have positive effect.The immersion of wild Flos Chrysanthemi Indici is to killing wriggler and fly larvae is also very effective.
Rhizoma Imperatae: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, cough due to lung-heat, gastropyretic vomiting, jaundice due to damp-heat, edema oliguria, the puckery pain of pyretic stranguria.
Herba Violae: Herba Violae mildly bitter flavor cold in nature, has effect of heat-clearing and toxic substances removing.Cure mainly jaundice, dysentery, mastitis, conjunctival congestion and swelling pain, pharyngitis; Traumatic injury, carbuncle, venom are controlled in external application.Flavonoid glycosides contained by Herba Violae and organic acid have stronger bacteriostasis to gold-coloured staphylococci, pig pasteurellosis bacillus, escherichia coli, streptococcus and Salmonella.Institute's Rich in Trace Element, effect is had to the activity of enzyme multiple in human body, direct or indirect effect is had to the synthesis of nucleic acid-protein, immunologic process, cell proliferation, epithelial cell reparation can be promoted, cell division is increased, and T cell increases, active increase, thus the immunologic function of organism is played regulatory role, play the regulation and control to organism metabolism by enzyme system.Contained zinc can antiviral, and can stimulate antitoxic synthesis, improves the resistance to infectious disease.
Rhizoma Acori Graminei: Herb fragrance, can make spice or mosquito dispersing; Stem, leaf can be used as medicine.[Tibetan medicine] list that: tuber controls influenza, anthrax, rheumatalgia; Leaf, flower, alabastrum control heat generation pain carbuncle, headache, toothache " Yunnan province will ".Root stock (calamus): bitter, pungent, temperature.Reduce phlegm, have one's ideas straightened out, spleen invigorating, dampness removing.For epilepsy, palpitate with fear forgetful, obnubilation, humidity hysteresis painful abdominal mass is swollen, dysentery, rheumatalgia, carbuncle scabies.Rhizoma Acori Graminei its flower, stem aromatic flavor, have have one's ideas straightened out, eliminate the phlegm, effect of loose wind, epidemic disease of can dispelling Fructus Alpiniae Oxyphyllae, building body.The successive dynasties classic of TCM is all using the medicine of Rhizoma Acori Graminei rhizome as Fructus Alpiniae Oxyphyllae the chest stuffiness relieving, hearing-improing and eyesight improving, damp eliminating removing toxic substances.
Flos Sophorae: cooling blood for hemostasis, purging liver-fire.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, spit blood, epistaxis, liver-heat conjunctival congestion, has a headache dizzy.
Cirsii japonici,radix: another name horse Ji, brave Ji, cat Ji, field thistle, Herba seu Radix Cirsii Japonici (Radix Saussureae cordifoliae), field thistle dish etc.Flavor efficacy is sweet, bitter, the cooler profit of property.Merit arrogates to oneself removing heat from blood, hemostasis, is applicable to treat the multiple hemorrhage caused by bleeding due to blood-heat, as spitting of blood, epistaxis, metrorrhagia, hematuria etc.; Be longer than blood stasis dispelling again, subduing inflammation, granulation promoting evacuation of pus.Can be used for treatment hemorrhoidal hamorrhage acute appendicitis, pain infections toxic swelling, furuncle, scrofula tuberculosis etc.
Herba Centellae: base is former: be dry herb or the whole herb with root of dicotyledon Umbelliferae Herba Centellae.Composition: containing the Triterpenoid of multiple α-balsam alcohol type, wherein have asiaticoside, thankuniside, isothankuniside, asiaticoside, Brahmoside, broken hot rice glycosides and Brahmic acid etc., and madasiatic acid.The property of medicine: bitter, acrid, cold.Return liver,spleen,kidney warp.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Be the long-lived medicine of Asians, can refresh oneself by beneficial brain.Research shows to have nourishing, antiinflammatory, healing of wound, diuresis relieving constipation and calm effect.Also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity, because it can stimulate the replacement of deep skin cell.It is neural nourishing agent, can improve memory, alleviate mental fatigue; Also can blood pressure lowering, treatment hepatopathy etc.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel.Composition: containing coumarin kind compound, volatile oil, acetas, angelol, thymol.Pharmacology: play a very important role to cardiovascular system, has the effect of blood pressure lowering, can promote hematoblastic gathering, have good analgesia and antiinflammatory action.There is anti-light quick effect, have significant curative effect to opposing tumor, anti-inflammation is also played a very important role.The property of medicine: bitter, tepor, pungent.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain.
Maifanitum: base is former: be Acid-intermediate igneous rock rocks beschtauite.Composition: Maifanitum main component has silicon dioxide, aluminium oxide, ferrum oxide, ferrous oxide, magnesium oxide, calcium oxide, sodium oxide, potassium oxide, titanium dioxide, phosphorus pentoxide, manganese oxide, carbon dioxide, and the trace element such as fluorine, sulfur, strontium, barium, copper, zinc.The property of medicine: " detailed outline ": " sweet, temperature, nontoxic." function cures mainly: removing toxic substances and promoting granulation, damp eliminating spleen invigorating.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.Generally make health product.
Chinese medicine preparation of the present invention is based on the principle of traditional Chinese medical herbal treatment allergic rhinitis, the Traditional Chinese medicinal spray that the medical material selected is made, directly act on affected part, rhinocnesmus, fluid stopping nasal mucus can be stopped fast, treat more comprehensive with heat-clearing and toxic substances removing, fast treating allergic rhinitis is primary treatment direction, has fabulous therapeutical effect to allergic rhinitis.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1: the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Flos Lonicerae 10 parts, Calamina 3 parts, Herba Pogostemonis 3 parts, Flos Chrysanthemi Indici 6 parts, Rhizoma Imperatae 3 parts, Herba Violae 3 parts, Rhizoma Acori Graminei 5 parts, 10 parts, Flos Sophorae, cirsii japonici,radix 3 parts, Herba Centellae 15 parts, Radix Angelicae Pubescentis 10 parts, Maifanitum 4 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned clinical care treatment of allergic rhinitis, step is as follows:
1. get clean Calamina and Maifanitum, smash, put in crucible, be fired to micro-red in smokeless stove fire, take out, pour leaching in basin immediately into and quench, stir, incline and suspension, rock ballast is dried, then calcine 2 times, finally rock ballast is discarded.Get suspension clarification, pour clear water into, by the fine powder drying for standby leached;
2. Herba Pogostemonis and Flos Chrysanthemi Indici are placed in preheated container, fry with moderate heat and take out to surperficial buff, grind to form last for subsequent use;
3. by Rhizoma Imperatae and cirsii japonici,radix clean water 3 times, be placed on preheated iron plate, repeatedly smoke 20 minutes, cool that to grind to form smalls stand-by;
4. Rhizoma Acori Graminei and Herba Centellae cleaned and drain away the water, get proper amount of edible oil and be placed in the Rhizoma Acori Graminei and Herba Centellae of to put into when surrounding is smoldered in pot in pot and draining away the water, micro-stir-fry, to buff, takes out that to grind to form smalls stand-by;
5. be layered on food steamer by Flos Lonicerae, Herba Violae, Flos Sophorae and Radix Angelicae Pubescentis mixing, yellow wine sprinklings in, slightly stewing 10 minutes, little fire steamed out blue or green taste, again evenly sprays yellow wine, steams 30 minutes, taking-up baking 1-2 hour, and it is stand-by to grind to form smalls;
6. step 1.-5. gained crude drug mixing, add ethanol, and decoct twice, add the ethanol of raw material gross weight 2 times for the first time, little fire simmers 20 minutes slowly, and ceaselessly stirs, filter, obtain filtrate 1, second time adds the ethanol of raw material gross weight 1 times, big fire is heated to boiling, changes little fire and decocts 10 minutes, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, must filtrate be mixed, after mixing filtrate being heated to boiling, leave standstill 10 hours, get supernatant loading air-tight bottle and namely obtain Traditional Chinese medicinal spray.
Model case one: Zhao XX, man, 15 years old, Jining, Shandong Province Zoucheng City.17 years old, rhinocnesmus, nasal obstruction, watery nasal discharge, sneeze 3 years, invalid through multi-treatment, meet wind then exacerbation of symptoms, dry mouth with bitter taste, red tongue, yellow fur, household very fear that band patient removes examination in hospital, be allergic rhinitis through hospital diagnosis.
Use embodiment 1 gained Traditional Chinese medicinal spray, get Traditional Chinese medicinal spray 1ml of the present invention at every turn, be sprayed on nasal cavity, patient's recovery from illness in 5 days, never recurrence after leaving hospital.
Embodiment 2: the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Flos Lonicerae 20 parts, Calamina 9 parts, Herba Pogostemonis 10 parts, Flos Chrysanthemi Indici 12 parts, Rhizoma Imperatae 9 parts, Herba Violae 10 parts, Rhizoma Acori Graminei 10 parts, 30 parts, Flos Sophorae, cirsii japonici,radix 6 parts, Herba Centellae 20 parts, Radix Angelicae Pubescentis 30 parts, Maifanitum 7 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned clinical care treatment of allergic rhinitis, step is as follows:
1. get clean Calamina and Maifanitum, smash, put in crucible, be fired to micro-red in smokeless stove fire, take out, pour leaching in basin immediately into and quench, stir, incline and suspension, rock ballast is dried, then calcine 6 times, finally rock ballast is discarded.Get suspension clarification, pour clear water into, by the fine powder drying for standby leached;
2. Herba Pogostemonis and Flos Chrysanthemi Indici are placed in preheated container, fry with moderate heat and take out to surperficial buff, grind to form last for subsequent use;
3. by Rhizoma Imperatae and cirsii japonici,radix clean water 7 times, be placed on preheated iron plate, repeatedly smoke 40 minutes, cool that to grind to form smalls stand-by;
4. Rhizoma Acori Graminei and Herba Centellae cleaned and drain away the water, get proper amount of edible oil and be placed in the Rhizoma Acori Graminei and Herba Centellae of to put into when surrounding is smoldered in pot in pot and draining away the water, micro-stir-fry, to buff, takes out that to grind to form smalls stand-by;
5. be layered on food steamer by Flos Lonicerae, Herba Violae, Flos Sophorae and Radix Angelicae Pubescentis mixing, yellow wine sprinklings in, slightly boil in a covered pot over a slow fire 30 minutes, little fire steams out blue or green taste, again evenly sprays yellow wine, steams 50 minutes, taking-up baking 2 hours, and it is stand-by to grind to form smalls;
6. step 1.-5. gained crude drug mixing, add ethanol, and decoct twice, add the ethanol of raw material gross weight 4 times for the first time, little fire simmers 40 minutes slowly, and ceaselessly stirs, filter, obtain filtrate 1, second time adds the ethanol of raw material gross weight 3 times, big fire is heated to boiling, changes little fire and decocts 20 minutes, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, must filtrate be mixed, after mixing filtrate being heated to boiling, leave standstill 20 hours, get supernatant loading air-tight bottle and namely obtain Traditional Chinese medicinal spray.
Embodiment 3: the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Flos Lonicerae 12 parts, Calamina 4 parts, Herba Pogostemonis 5 parts, Flos Chrysanthemi Indici 8 parts, Rhizoma Imperatae 4 parts, Herba Violae 5 parts, Rhizoma Acori Graminei 6 parts, 12 parts, Flos Sophorae, cirsii japonici,radix 4 parts, Herba Centellae 16 parts, Radix Angelicae Pubescentis 15 parts, Maifanitum 18 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned clinical care treatment of allergic rhinitis, step is as follows:
1. get clean Calamina and Maifanitum, smash, put in crucible, be fired to micro-red in smokeless stove fire, take out, pour leaching in basin immediately into and quench, stir, incline and suspension, rock ballast is dried, then calcine 3 times, finally rock ballast is discarded.Get suspension clarification, pour clear water into, by the fine powder drying for standby leached;
2. Herba Pogostemonis and Flos Chrysanthemi Indici are placed in preheated container, fry with moderate heat and take out to surperficial buff, grind to form last for subsequent use;
3. by Rhizoma Imperatae and cirsii japonici,radix clean water 4 times, be placed on preheated iron plate, repeatedly smoke 25 minutes, cool that to grind to form smalls stand-by;
4. Rhizoma Acori Graminei and Herba Centellae cleaned and drain away the water, get proper amount of edible oil and be placed in the Rhizoma Acori Graminei and Herba Centellae of to put into when surrounding is smoldered in pot in pot and draining away the water, micro-stir-fry, to buff, takes out that to grind to form smalls stand-by;
5. be layered on food steamer by Flos Lonicerae, Herba Violae, Flos Sophorae and Radix Angelicae Pubescentis mixing, yellow wine sprinklings in, slightly boil in a covered pot over a slow fire 15 minutes, little fire steams out blue or green taste, again evenly sprays yellow wine, steams 35 minutes, taking-up baking 1.3 hours, and it is stand-by to grind to form smalls;
6. step 1.-5. gained crude drug mixing, add ethanol, and decoct twice, add the ethanol of raw material gross weight 2.5 times for the first time, little fire simmers 25 minutes slowly, and ceaselessly stirs, filter, obtain filtrate 1, second time adds the ethanol of raw material gross weight 1.5 times, big fire is heated to boiling, changes little fire and decocts 13 minutes, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, must filtrate be mixed, after mixing filtrate being heated to boiling, leave standstill 13 hours, get supernatant loading air-tight bottle and namely obtain Traditional Chinese medicinal spray.
Model case two: tight XX, female, 29 years old, Shanting District of Zaozhuang City of Shandong Province.Symptom: allergic rhinitis 3 years, often because of contact cold air and penetrating odor and increasing the weight of, nasal obstruction, sneeze, a large amount of clear water nasal mucus, rhinocnesmus, lazy speech of breathing hard, time have anemophobia to be afraid of cold, pale tongue, thin fur, Sublingual venation is purple dark, weak pulse.
Use embodiment 3 gained Traditional Chinese medicinal spray, get Traditional Chinese medicinal spray 2ml of the present invention at every turn, be sprayed on nasal cavity, within 2 days, patients symptomatic improves, through repeatedly spraying medicine patient's recovery from illness in 7 days, never in recurrence.
Embodiment 4: the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Flos Lonicerae 18 parts, Calamina 7 parts, Herba Pogostemonis 8 parts, Flos Chrysanthemi Indici 10 parts, Rhizoma Imperatae 6 parts, Herba Violae 8 parts, Rhizoma Acori Graminei 8 parts, 20 parts, Flos Sophorae, cirsii japonici,radix 5 parts, Herba Centellae 19 parts, Radix Angelicae Pubescentis 25 parts, Maifanitum 25 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned clinical care treatment of allergic rhinitis, step is as follows:
1. get clean Calamina and Maifanitum, smash, put in crucible, be fired to micro-red in smokeless stove fire, take out, pour leaching in basin immediately into and quench, stir, incline and suspension, rock ballast is dried, then calcine 5 times, finally rock ballast is discarded.Get suspension clarification, pour clear water into, by the fine powder drying for standby leached;
2. Herba Pogostemonis and Flos Chrysanthemi Indici are placed in preheated container, fry with moderate heat and take out to surperficial buff, grind to form last for subsequent use;
3. by Rhizoma Imperatae and cirsii japonici,radix clean water 6 times, be placed on preheated iron plate, repeatedly smoke 35 minutes, cool that to grind to form smalls stand-by;
4. Rhizoma Acori Graminei and Herba Centellae cleaned and drain away the water, get proper amount of edible oil and be placed in the Rhizoma Acori Graminei and Herba Centellae of to put into when surrounding is smoldered in pot in pot and draining away the water, micro-stir-fry, to buff, takes out that to grind to form smalls stand-by;
5. be layered on food steamer by Flos Lonicerae, Herba Violae, Flos Sophorae and Radix Angelicae Pubescentis mixing, yellow wine sprinklings in, slightly boil in a covered pot over a slow fire 25 minutes, little fire steams out blue or green taste, again evenly sprays yellow wine, steams 45 minutes, taking-up baking 1.8 hours, and it is stand-by to grind to form smalls;
6. step 1.-5. gained crude drug mixing, add ethanol, and decoct twice, add the ethanol of raw material gross weight 3.5 times for the first time, little fire simmers 35 minutes slowly, and ceaselessly stirs, filter, obtain filtrate 1, second time adds the ethanol of raw material gross weight 2.5 times, big fire is heated to boiling, changes little fire and decocts 18 minutes, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, must filtrate be mixed, after mixing filtrate being heated to boiling, leave standstill 18 hours, get supernatant loading air-tight bottle and namely obtain Traditional Chinese medicinal spray.
Model case Mibayashi XX, man, 17 years old, Tang Kou street, Shizhong District, Jining of Shandong Province city.Symptom: often unknown cause nasal obstruction, stream clear water tears, rhinocnesmus, throat is uncomfortable, and with light inflammation, cough, hyposmia, go hospitalize after many times, effect is all undesirable, has had a strong impact on normal learning life.
Use embodiment 4 gained Traditional Chinese medicinal spray, get Traditional Chinese medicinal spray 3ml of the present invention at every turn, be sprayed on nasal cavity, within 2 days, patients symptomatic improves, through repeatedly spraying medicine patient's recovery from illness in 7 days, never in recurrence.
Embodiment 5: the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Flos Lonicerae 15 parts, Calamina 6 parts, Herba Pogostemonis 6 parts, Flos Chrysanthemi Indici 9 parts, Rhizoma Imperatae 5 parts, Herba Violae 6 parts, Rhizoma Acori Graminei 7 parts, 15 parts, Flos Sophorae, cirsii japonici,radix 4.5 parts, Herba Centellae 17 parts, Radix Angelicae Pubescentis 20 parts, Maifanitum 6 parts.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned clinical care treatment of allergic rhinitis, step is as follows:
1. get clean Calamina and Maifanitum, smash, put in crucible, be fired to micro-red in smokeless stove fire, take out, pour leaching in basin immediately into and quench, stir, incline and suspension, rock ballast is dried, then calcine 4 times, finally rock ballast is discarded.Get suspension clarification, pour clear water into, by the fine powder drying for standby leached;
2. Herba Pogostemonis and Flos Chrysanthemi Indici are placed in preheated container, fry with moderate heat and take out to surperficial buff, grind to form last for subsequent use;
3. by Rhizoma Imperatae and cirsii japonici,radix clean water 5 times, be placed on preheated iron plate, repeatedly smoke 30 minutes, cool that to grind to form smalls stand-by;
4. Rhizoma Acori Graminei and Herba Centellae cleaned and drain away the water, get proper amount of edible oil and be placed in the Rhizoma Acori Graminei and Herba Centellae of to put into when surrounding is smoldered in pot in pot and draining away the water, micro-stir-fry, to buff, takes out that to grind to form smalls stand-by;
5. be layered on food steamer by Flos Lonicerae, Herba Violae, Flos Sophorae and Radix Angelicae Pubescentis mixing, yellow wine sprinklings in, slightly boil in a covered pot over a slow fire 20 minutes, little fire steams out blue or green taste, again evenly sprays yellow wine, steams 40 minutes, taking-up baking 1.5 hours, and it is stand-by to grind to form smalls;
6. step 1.-5. gained crude drug mixing, add ethanol, and decoct twice, add the ethanol of raw material gross weight 3 times for the first time, little fire simmers 30 minutes slowly, and ceaselessly stirs, filter, obtain filtrate 1, second time adds the ethanol of raw material gross weight 2 times, big fire is heated to boiling, changes little fire and decocts 15 minutes, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, must filtrate be mixed, after mixing filtrate being heated to boiling, leave standstill 15 hours, get supernatant loading air-tight bottle and namely obtain Traditional Chinese medicinal spray.
Experimental example: in order to verify the effect of Traditional Chinese medicinal spray of the present invention, we have chosen 400 Allergic Rhinitis in 4 hospitals, have carried out the experiment (embodiment 5) of medicine, and have carried out statistics and mathematical analysis to data accurately.Specific experiment result is as following table:
Table 1
Table 2:
Traditional Chinese medicinal spray of the present invention side effect compared with the medicine of other treatment of allergic rhinitis is little, Traditional Chinese medicinal spray of the present invention just can alleviate rapidly the heavy malaise symptoms of nasal obstruction, brains at the use initial stage, increase the confidence of patient's cure diseases, and it is cheap, ordinary people life-time service, also health and pecuniary burden can not be increased, and radical cure allergic rhinitis that can be real, making the healing of allergic rhinitis be no longer can to ask and unavailable, is the ideal safe Traditional Chinese medicinal spray of current treatment of allergic rhinitis.
Claims (10)
1. the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Flos Lonicerae 10-20 part, Calamina 3-9 part, Herba Pogostemonis 3-10 part, Flos Chrysanthemi Indici 6-12 part, Rhizoma Imperatae 3-9 part, Herba Violae 3-10 part, Rhizoma Acori Graminei 5-10 part, Flos Sophorae 10-30 part, cirsii japonici,radix 3-6 part, Herba Centellae 15-20 part, Radix Angelicae Pubescentis 10-30 part, Maifanitum 4-7 part.
2. the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Flos Lonicerae 12-18 part, Calamina 4-7 part, Herba Pogostemonis 5-8 part, Flos Chrysanthemi Indici 8-10 part, Rhizoma Imperatae 4-6 part, Herba Violae 5-8 part, Rhizoma Acori Graminei 6-8 part, Flos Sophorae 12-20 part, cirsii japonici,radix 4-5 part, Herba Centellae 16-19 part, Radix Angelicae Pubescentis 15-25 part, Maifanitum 18-25 part.
3. the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Flos Lonicerae 15 parts, Calamina 6 parts, Herba Pogostemonis 6 parts, Flos Chrysanthemi Indici 9 parts, Rhizoma Imperatae 5 parts, Herba Violae 6 parts, Rhizoma Acori Graminei 7 parts, 15 parts, Flos Sophorae, cirsii japonici,radix 4.5 parts, Herba Centellae 17 parts, Radix Angelicae Pubescentis 20 parts, Maifanitum 6 parts.
4. the preparation method of the Traditional Chinese medicinal spray of clinical care treatment of allergic rhinitis according to any one of claim 1-3, is characterized in that: step is as follows:
1. get clean Calamina and Maifanitum, smash, put in crucible, be fired to micro-red in smokeless stove fire, take out, pour leaching in basin immediately into and quench, stir, incline and suspension, rock ballast is dried, then calcine 2-6 time, finally rock ballast is discarded.Get suspension clarification, pour clear water into, by the fine powder drying for standby leached;
2. Herba Pogostemonis and Flos Chrysanthemi Indici are placed in preheated container, fry with moderate heat and take out to surperficial buff, grind to form last for subsequent use;
3. by Rhizoma Imperatae and cirsii japonici,radix clean water 3-7 time, be placed on preheated iron plate, repeatedly smoke 20-40 minute, cool that to grind to form smalls stand-by;
4. Rhizoma Acori Graminei and Herba Centellae cleaned and drain away the water, get proper amount of edible oil and be placed in the Rhizoma Acori Graminei and Herba Centellae of to put into when surrounding is smoldered in pot in pot and draining away the water, micro-stir-fry, to buff, takes out that to grind to form smalls stand-by;
5. be layered on food steamer by Flos Lonicerae, Herba Violae, Flos Sophorae and Radix Angelicae Pubescentis mixing, yellow wine sprinklings in, slightly stewing 10-30 minute, little fire steams out blue or green taste, again evenly sprays yellow wine, steams 30-50 minute, taking-up baking 1-2 hour, and it is stand-by to grind to form smalls;
6. step 1.-5. gained crude drug mixing, add ethanol, and decoct twice, first time adds raw material gross weight 2-4 ethanol doubly, and little fire simmers 20-40 minute slowly, and ceaselessly stirs, filter, obtain filtrate 1, second time adds raw material gross weight 1-3 ethanol doubly, big fire is heated to boiling, changes little fire and decocts 10-20 minute, filter, obtain filtrate 2, filtrate 1 and filtrate 2 are mixed, must filtrate be mixed, after mixing filtrate being heated to boiling, leave standstill 10-20 hour, get supernatant loading air-tight bottle and namely obtain Traditional Chinese medicinal spray.
5. the preparation method of Traditional Chinese medicinal spray according to claim 4, is characterized in that: 1. rock ballast dries by step, then calcines 3-5 time (preferred, to be dried by rock ballast, then calcine 4 times).
6. the preparation method of Traditional Chinese medicinal spray according to claim 4, it is characterized in that: step is 3. by Rhizoma Imperatae and cirsii japonici,radix clean water 4-6 time, be placed on preheated iron plate, repeatedly smoke 25-35 minute (preferably, by Rhizoma Imperatae and cirsii japonici,radix clean water 5 times, be placed on preheated iron plate, repeatedly smoke 30 minutes).
7. the preparation method of Traditional Chinese medicinal spray according to claim 4, is characterized in that: 5. step sprays yellow wine, slightly stewing 15-25 minute (preferred, yellow wine in sprinklings, slightly boils in a covered pot over a slow fire 20 minutes).
8. the preparation method of Traditional Chinese medicinal spray according to claim 4, is characterized in that: 5. step evenly sprays yellow wine again, steams 35-45 minute, take out and dry 1.3-1.8 hour (preferably, again evenly spray yellow wine, steam 40 minutes, take out baking 1.5 hours).
9. the preparation method of Traditional Chinese medicinal spray according to claim 4, it is characterized in that: 6. first time adds raw material gross weight 2.5-3.5 ethanol doubly to step, little fire is simmered 25-35 minute (preferred, add the ethanol of raw material gross weight 3 times for the first time, little fire simmers 30 minutes slowly) slowly.
10. the preparation method of Traditional Chinese medicinal spray according to claim 4, it is characterized in that: step 6. second time adds raw material gross weight 1.5-2.5 ethanol doubly, big fire is heated to boiling, change little fire and decoct 13-18 minute (preferably, second time adds the ethanol of raw material gross weight 2 times, big fire is heated to boiling, changes little fire and decocts 15 minutes).
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| CN105902910A (en) * | 2016-06-21 | 2016-08-31 | 刘文峰 | Respiratory tract infection treating drop for pediatric nursing and preparation method thereof |
| CN114470024A (en) * | 2022-03-22 | 2022-05-13 | 杨鑫 | A herbal egg for treating rhinitis and its preparation method |
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| CN102670683A (en) * | 2012-05-22 | 2012-09-19 | 王瑞台 | Chinese medicinal composition for treating allergic rhinitis |
| CN104042814A (en) * | 2014-06-25 | 2014-09-17 | 梁黎明 | Traditional Chinese medicinal composition for treating anaphylactic rhinitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105902910A (en) * | 2016-06-21 | 2016-08-31 | 刘文峰 | Respiratory tract infection treating drop for pediatric nursing and preparation method thereof |
| CN114470024A (en) * | 2022-03-22 | 2022-05-13 | 杨鑫 | A herbal egg for treating rhinitis and its preparation method |
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