CN105456708A

CN105456708A - Drug for treating cheilitis and preparation method thereof

Info

Publication number: CN105456708A
Application number: CN201511025107.2A
Authority: CN
Inventors: 王睿超
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-30
Filing date: 2015-12-30
Publication date: 2016-04-06
Anticipated expiration: 2035-12-30
Also published as: CN105456708B

Abstract

The invention belongs to the technical field of traditional Chinese medicine preparation, and particularly relates to a drug for treating cheilitis and a preparation method thereof. The drug for treating the cheilitis mainly comprises a bag A composed of olive oil, honey, glycerinum and the like, a bag B composed of urea, a vitamin A, a vitamin D and the like and a traditional Chinese medicine bag, and the drug for treating the cheilitis is prepared through a special preparation method. By means of rational compatibility, mutual synergy and mutual promotion of all the effective components, an ointment product which is significant in drug efficacy and special for the cheilitis is obtained and is suitable for various cheilitis, the pertinence is high, efficacy is quick to achieve, the curative effect is significant, toxic and side effects do not exist, the symptoms and discomfort of dry cracks, red swelling, desquamation, fester and pain can be treated in a targeted mode, the drug is free of any hormone component, the course of treatment is short, the long-term curative effect is good, side effects are not caused, and the cure rate is high.

Description

A kind of medicine being used for the treatment of cheilitis and preparation method thereof

(1) technical field

The invention belongs to technical field of traditional Chinese medicine preparation, particularly a kind of medicine being used for the treatment of cheilitis and preparation method thereof.

(2) background technology

Cheilitis is one group of more common chronic Mucosa of lip disease, and its cardinal symptom has lip red and swollen, rotten to the corn etc., and this is a kind of disease having very large harm.Cause the reason of inflammation on lips, mainly comprise following several situation: be often in dry weather, under cold wind blows, cause lip mucosa moisture retention to be deteriorated, and the pure cheilitis of easily peeling, peeling off, splitting; Often because of caused by body constitution allergy, the good patient sent out in atopic dermatitis or seborrheic dermatitis, may irradiate or touch the relevant exfoliation cheilitis of pungent, common what lower lip with sunlight; Because rouging the lip pomade cheilitis caused, cause because of life-time service lipstick, this kind of patient goes up lower lip usually all can symptom; Movable under burning sun or worker for a long time, under ultraviolet chronic stimulation, cause lower lip to become paler, atrophy of epidermis, be full of cracks, even likely develop into malignant change, belongs to solar lentigines cheilitis.

Generation, the development of above-mentioned all kinds of cheilitis all bring unlimited misery to patient, have had a strong impact on work and quality of life.Therefore, cheilitis first should to put prevention first, and can have and moisten the lip pomade nourishing effect and maintain wiping at ordinary times protector, once cheilitis occurs, the medicine had for therapeutic effect should be selected to carry out active treatment.At present, treatment cheilitis generally uses the corticosteroid hormone ointment of external, if the state of an illness is the symptoms such as lip is plump, stiff, can adopt surgical operation, laser lamp Therapeutic Method, but all there is side effect in above method, and be difficult to be completely cured, easy recurrence, effect is undesirable.

(3) summary of the invention

In order to make up the deficiencies in the prior art, the invention provides a kind of prepare simple, with strong points, prove effective fast, evident in efficacy and medicine being used for the treatment of cheilitis had no side effect and preparation method thereof.This medicine being used for the treatment of cheilitis is made unguentum and is used easy to carry, can dry and cracked, red and swollen, the desquamation of peeling of immunotherapy targeted autoantibody cheilitis, fester, the symptom of pain and discomfort, there is good therapeutical effect, not containing any hormone medicine, short treating period, late result is good, do not produce any side effect, cure rate is high, solves the misery of patient, solves problems of the prior art.

The present invention is achieved through the following technical solutions:

Be used for the treatment of a medicine for cheilitis, its active component is made up of the raw material of following parts by weight:

Olive oil 35-45 part, Mel 4-12 part, glycerol 12-20 part, azone 1-5 part, Tween 80 0.5-2 part, diphenhydramine 0.5-1.5 part; Carbamide 0.5-1.5 part, vitamin A 0.5-1.5 part, vitamin D 0.5-1.5 part, vitamin E 0.5-1.5 part, vitamin B12 0.5-1.5 part; Middle medicated bag 10-15 part;

The active component of described middle medicated bag is made up of the raw material of following parts by weight:

Fructus Aurantii 6-12 part, Medulla Tetrapanacis 5-15 part, Fructus Cnidii 10-20 part, Herba Asari 10-20 part, Bulbus Fritillariae Cirrhosae 10-20 part, Herba Spirodelae 9-15 part, Radix Rehmanniae 15-25 part, Fructus Forsythiae 15-25 part, Radix Scrophulariae 15-25 part, Flos Lonicerae 15-25 part, Radix Adenophorae (Radix Glehniae) 10-20 part, Radix Trichosanthis 10-20 part, Radix Asparagi 10-20 part, Radix Platycodonis 10-20 part, Radix Ophiopogonis 10-20 part, Rhizoma Polygonati Odorati 10-20 part, Bulbus Lilii 25-35 part, Rhizoma Belamcandae 5-15 part, Radix Glycyrrhizae 4-8 part.

This is used for the treatment of the medicine of cheilitis, and its preferred each active component is made up of the raw material of following parts by weight:

40 parts, olive oil, Mel 8 parts, glycerol 16 parts, azone 3 parts, Tween 80 1 part, diphenhydramine 1 part; 1 part, carbamide, retinol1 part, vitamin D1 part, vitamin e1 part, vitamin B12 1 part; Middle medicated bag 12 parts;

The active component of described middle medicated bag is preferably made up of the raw material of following parts by weight:

Fructus Aurantii 9 parts, Medulla Tetrapanacis 10 parts, Fructus Cnidii 15 parts, Herba Asari 15 parts, Bulbus Fritillariae Cirrhosae 15 parts, 12 parts, Herba Spirodelae, 20 parts, the Radix Rehmanniae, Fructus Forsythiae 20 parts, Radix Scrophulariae 20 parts, Flos Lonicerae 20 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Trichosanthis 15 parts, Radix Asparagi 15 parts, Radix Platycodonis 15 parts, Radix Ophiopogonis 15 parts, Rhizoma Polygonati Odorati 15 parts, Bulbus Lilii 30 parts, Rhizoma Belamcandae 10 parts, 6 parts, Radix Glycyrrhizae.

This is used for the treatment of the preparation method of the medicine of cheilitis, adopts following steps preparation:

A, the olive oil getting above-mentioned parts by weight, Mel, glycerol, azone, Tween 80, diphenhydramine are mixed to get A bag, for subsequent use;

B, the carbamide getting above-mentioned parts by weight, vitamin A, vitamin D, vitamin E, vitamin B12 are mixed to get B bag, for subsequent use;

C, get each taste Chinese medicine of above-mentioned parts by weight, dry, pulverize, crossing 200-400 mesh sieve must mix Chinese medicinal powder;

D, the ethanol adding 75% in the mixing Chinese medicinal powder of step c infiltrate 24-30h, then load in percolator, constantly add 75% alcoholic solution and carry out percolation, collect leachate, for subsequent use; Wherein, the weight of 75% total alcoholic solution that percolation process adds be the 5-7 of step c Chinese medicinal powder weight doubly;

E, by steps d collect leachate be evaporated to without ethanol taste, recovery ethanol, obtain the concentrated liquid of tradition Chinese medicine;

F, the B bag obtained by step b add in the obtained A bag of step a, stir, then add the obtained the concentrated liquid of tradition Chinese medicine of step e, continue to stir 20-25 minute to evenly, obtain mixed solution;

G, the mixed solution heating in water bath obtained by step f, heating-up temperature 65-70 DEG C, heating 10-15min, to obtain final product.

This is used for the medicine of prevention and therapy cheilitis, and its active component can also be made up of the raw material of following parts by weight:

Olive oil 35-45 part, Mel 4-12 part, glycerol 12-20 part, azone 1-5 part, Tween 80 0.5-2 part, diphenhydramine 0.5-1.5 part; Carbamide 0.5-1.5 part, vitamin A 0.5-1.5 part, vitamin D 0.5-1.5 part, vitamin E 0.5-1.5 part, vitamin B12 0.5-1.5 part; Middle medicated bag 10-15 part; Natural Cera Flava 10-16 part, quintessence oil 1-3 part;

The above-mentioned medicine being used for the treatment of cheilitis, its preferred each active component is made up of the raw material of following parts by weight:

40 parts, olive oil, Mel 8 parts, glycerol 16 parts, azone 3 parts, Tween 80 1 part, diphenhydramine 1 part; 1 part, carbamide, retinol1 part, vitamin D1 part, vitamin e1 part, vitamin B12 1 part; Middle medicated bag 12 parts; 13 parts, natural Cera Flava, quintessence oil 2 parts;

Fructus Aurantii 9 parts, Medulla Tetrapanacis 10 parts, Fructus Cnidii 15 parts, Herba Asari 15 parts, Bulbus Fritillariae Cirrhosae 12 parts, 12 parts, Herba Spirodelae, 20 parts, the Radix Rehmanniae, Fructus Forsythiae 20 parts, Radix Scrophulariae 20 parts, Flos Lonicerae 20 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Trichosanthis 15 parts, Radix Asparagi 15 parts, Radix Platycodonis 15 parts, Radix Ophiopogonis 15 parts, Rhizoma Polygonati Odorati 15 parts, Bulbus Lilii 30 parts, Rhizoma Belamcandae 10 parts, 6 parts, Radix Glycyrrhizae.

The above-mentioned preparation method being used for the treatment of the medicine of cheilitis, adopts following steps preparation:

C, get each taste Chinese medicine of above-mentioned parts by weight, dry, pulverize, cross 200-400 mesh sieve and be mixed to get Chinese medicinal powder;

G, the mixed solution heating in water bath that step f is obtained, heating-up temperature 65-70 DEG C, heating 10-15min, period adds the natural Cera Flava of above-mentioned parts by weight and dissolves completely; After having heated, add the quintessence oil of above-mentioned parts by weight, stir to obtain unguentum.

The present invention is used for the treatment of the usage and dosage of the medicine of cheilitis: liquid formulation: respectively smear once in the morning, afternoon in the daytime, and lip portion is dry and cracked, wound location to adopt spot printing method to smear; Smear before sleeping evening once, spot printing method smears that lip portion is dry and cracked, wound location, and applying amount is daytime 2 times of ampoule.Unguentum: respectively smear once in the morning, afternoon in the daytime, applying amount is thin layer; Smear again before sleeping evening, applying amount be daytime ampoule 2-3 doubly.Anemia of pregnant woman is forbidden.

The pharmaceutical characteristic of middle medicated bag of the present invention and other each active component is as follows:

Middle medicated bag:

Fructus Aurantii: nature and flavor toil is cool.Enter lung, spleen, large intestine channel.Function cures mainly: dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting.Containing the material such as volatile oil and flavonoid glycoside in Fructus Aurantii, simultaneously containing vitamin C.

Medulla Tetrapanacis: property slightly sweet flavor is cool.Enter lung, stomach warp.Function cures mainly: eliminating the pathogens from the lung, diuresis, lower milk.Control dysuria, gonorrhea, edema, blurred vision, nasal obstruction.

Fructus Cnidii: nature and flavor are pungent, bitter, temperature; Slightly poisonous.Return kidney channel.Function cures mainly: warming the kidney to invigorate YANG, and dampness is dispeled the wind, parasite killing.

Herba Asari: nature and flavor are pungent, temperature.GUIXIN, lung, kidney channel.Expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.

Bulbus Fritillariae Cirrhosae: property bitter but sweet flavor is cool.Enter lung meridian.Function cures mainly: lung moistening eliminating stagnation, antitussive reduces phlegm.Control cough due to consumptive disease, spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, honest and clean scrofula, sore throat, acute mastitis.

Herba Spirodelae: acrid in the mouth, cold in nature, return lung, urinary bladder channel; Relieving the exterior syndrome by diaphoresis, inducing diuresis to remove edema, rash is antipruritic.

The Radix Rehmanniae: cold in nature and stagnant, has clearing away heat and cooling blood effect, to join the army blood for warm febrile disease, high fever coma, xerostomia crimson tongue.

Fructus Forsythiae: nature and flavor: bitter, cool.Enter the heart, liver, gallbladder meridian.Heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Function cures mainly: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Fructus Forsythiae antimicrobial spectrum is very wide, has obvious antiinflammatory action, can promote the formation of inflammatory barrier, reduces capillary permeability, reduces inflammatory exudation, eliminates the lip redness that cheilitis causes.

Radix Scrophulariae: nature and flavor hardship is salty, cool.Enter lung, kidney channel.Function cures mainly: YIN nourishing, pathogenic fire reducing, relieving restlessness, removing toxic substances.Control consumption of YIN caused by febrile disease, tongue unravels silk excessive thirst, sends out speckle, hectic fever due to YIN-deficiency consumptive fever, and sleep night not peaceful, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula, maculae caused by violent heat pathogen, conjunctival congestion, diphtheria, sore.

Flos Lonicerae: nature and flavor are sweet, cold.Gas fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Return lung, stomach, large intestine channel.Function cures mainly: heat-clearing and toxic substances removing.Main epidemic febrile disease heating; Toxic-heat and blood stasis; Carbuncle furuncle; Sore throat and multi-infection disease, have removing toxic substances, antiinflammatory, virus killing, sterilization, antipruritic effect, resisting pathogenic microbes.Flos Lonicerae can dispelling wind-heat, and also kind removing summer-heat blood poison, is applicable to various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.The title that in application, Flos Lonicerae has from ancient times " panacea of infections section ".Be described as the good medicine protecting the moon, removing heat from blood, heat-clearing and toxic substances removing.Kind removing summer-heat blood poison, for various for skin ulcer, carbuncle, furuncle and phyma, is the heat and toxic materials clearing away medicine that surgery is conventional.Have and strengthen immunity, the function that strengthens the defense effect: be antiinflammatory, antipyretic.Promote the release of adrenocortical hormone, have obvious inhibitory action to inflammation.

Radix Adenophorae (Radix Glehniae): sweet and slightly bitter taste, cold nature.Attach to the lung and stomach meridians.There is clearing away heat and nourishing YIN, effect of nourishing the lung to arrest cough.Cure mainly tracheitis, pertussis, cough due to lung-heat, cough up phlegm yellow thick.

Radix Trichosanthis: sweet in the mouth sweetness and bitterness acid is cool.Enter lung, stomach warp.Function cures mainly: promote the production of body fluid, and quenches the thirst, and pathogenic fire reducing is moisturized, evacuation of pus, detumescence.

Radix Asparagi: cold in nature, sweet in the mouth, hardship.Function cures mainly: YIN nourishing and the production of body fluid promoting, and lung moistening clears away heart-fire.Quench one's thirst for dryness of the lung dry cough, cough due to consumptive disease, thirsty, the vexed insomnia of Tianjin wound, interior-heat, dryness of the intestine constipation, diphtheria.

Radix Platycodonis: nature and flavor toil is flat.Enter lung, stomach warp.Function cures mainly: open lung qi dispersing gas, evacuation of pus of eliminating the phlegm.Control exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery is suffered from abdominal pain.

Radix Ophiopogonis: nature and flavor are sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.Function cures mainly: YIN nourishing and the production of body fluid promoting, nourishing the lung to arrest cough: few thirsty, the dry cough spitting of blood in the Tianjin for lung-stomach yin deficiency; The cards such as the palpitation and being susceptible to fright of insufficiency of heart-YIN and calentura later stage consumption of body fluid by heat.Join Radix Adenophorae (Radix Glehniae), Bulbus Fritillariae Cirrhosae can control deficiency of lung-YIN dry cough.

Rhizoma Polygonati Odorati: nature and flavor are sweet, is slightly cold.Attach to the lung and stomach meridians.Function cures mainly: nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.For lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.

Bulbus Lilii: nature and flavor are sweet, cold.GUIXIN, lung meridian.Function cures mainly: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.

Rhizoma Belamcandae: bitter, cold.Return lung meridian.Function cures mainly: heat-clearing and toxic substances removing, expectorant, sore-throat relieving.For the pent-up of pyretic toxicity phlegm-fire, laryngopharynx swelling and pain, accumulation and obstruction of sputum, cough and asthma.

Radix Glycyrrhizae: the effect with heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, decocts soup external, can treat that cheilosis, corners of the mouth breach are hemorrhage, pain.

A wraps:

Olive oil: the good reputation enjoying " liquid golden ", " beauty treatment god oil ".Be stained with appropriate olive oil by cotton pads before generally sleeping and cover lip, adhere to several days, lip will be moistening full.Effect: anti-inflammation, short absorption, blood circulation promoting, nourishing effect.

Mel: nature and flavor: sweet is flat.Enter lung, board, large intestine channel.Function cures mainly: invigorating middle warmer, moisturizes, pain relieving, removing toxic substances.According to Compendium of Material Medica: " merit of being used as medicine has five, and also, also, also, moisturize also, pain relieving also in removing toxic substances in invigorating middle warmer in heat clearing away.Raw then cool in nature, therefore can heat clearing away; Ripe then warm in nature, therefore energy invigorating middle warmer; Sweet and gentle, therefore can detoxify; Soft and Ru Ze, therefore can moisturize; Delay and can go urgency, therefore trusted subordinate's muscle skin infection pain can be stopped; In can causing, therefore hundred medicines can be in harmonious proportion, and merit same with Radix Glycyrrhizae ".It is on the one hand as the intermixture making unguentum, can also moisturize in addition, pain relieving, granulation promoting.

Glycerol: effect: have outside moisturizing, humectation function, also has high activity, antioxidation, short alcoholization.

Azone: effect: penetrating agent.

Tween 80: solubilizing agent, can disturb the effect of antibacterial in the solution.

Diphenhydramine: cure mainly various Mucocutaneous allergic disease, comprise various dermatitis, eczema, urticaria, drug eruption, allergic rhinitis etc.

B wraps:

Carbamide: improve the humidity of skin, moisturizing humectation.

Vitamin A: effect: growth promoting effects and reproduction, contributes to protecting epidermis, and mucosa is not by bacterial infestation.

Vitamin D: be mainly used in forming and maintaining the strong of skeleton; Enhancing immunity.

Vitamin E: prevention of inflammation dermatoses; Protection skin, from the injury of ultraviolet and pollution, reduces the deposition of cicatrix and pigment; The healing of accelerated in wounds.

Vitamin B12: lack vitamin B12 and tongue, oral cavity, gastral mucosa irritation easily occur.

Other compositions:

Natural Cera Flava is four pairs of wax gland secretion shopping matter below worker bee abdominal part, and its Main Ingredients and Appearance has: acids, free fatty, free alkyl alcohol, carbohydrate, carotenoid, vitamin A, aromatic substance etc.Cera Flava is a herb material, has astringent therapy, sore, granulation promoting, pain relieving, effect of conditioning, and outward for ulcer being unable to heal, ecthyma is rotten to the corn, wound, the diseases such as burn.Quintessence oil: there is as antibacterial the effect suppressing pathogen growth.

A bag has effect that is moist, that repair and treat to the skin at cheilitis position, can strengthen the sterilization of medicament, antiseptic property; Wherein the adding of diphenhydramine, the reparation of skin mucosa can be promoted further, prevent the red swelling of the skin at lip position, dry and cracked aggravation; Tween 80 is as solubilizing agent, the effect of solubilising can be played on the one hand, on the other hand, it can play good suppression and regulating action to the effectiveness of the antipathogenic compositions such as the quintessence oil in unguentum, because of the inhibitor that quintessence oil is various antibacterial and pathogenic bacteria, simultaneously also can produce certain impact to beneficial bacteria to killing of harmful levels of pathogens, Tween 80 just in time makes up this deficiency, to ensure that in this product unguentum antibacterial have more play sterilization targetedly, effectiveness of sterilizing.B bag vitamin ingredients can strengthen to a certain extent unguentum go dry and cracked, go atrophy effect.Middle medicated bag is used for the treatment of the main active of the medicine of cheilitis as this, according to theory of Chinese medical science " The mouth is the body opening or window of the spleen, and its China is at lip ", the medical concept according to " cheilitis is caused by the heresy that wind-fire is damp and hot " clicks medicine, medication.Above three kinds of medicated bags are mutually promoted, and permeate entirety mutually, concurrence clearing away heat and expelling wind, separate effect that is scorchingly hot, putrefaction removing and tissue regeneration promoting, remove the misery of cheilitis patient, meanwhile, can enhancing human body immunity power, maintain body health, therapeutic effect is remarkable, good effect.

Fructus Aurantii dispelling the stagnated QI, removing food stagnancy in middle medicated bag, coordinate Medulla Tetrapanacis, Radix Scrophulariae, Flos Lonicerae to use, energy antiinflammatory, heat clearing away, detumescence, slow down the discomfort of cheilitis patient oral area redness; Fructus Cnidii, Bulbus Fritillariae Cirrhosae and Herba Spirodelae are with the use of dispelling wind pathogens; Herba Asari expelling wind and cold, understand things pain-stopping; Flos Lonicerae is cold in nature, has the merit of clearing away heat and cooling blood, removing toxic substances, rash, coordinates the Radix Rehmanniae, Fructus Forsythiae, Rhizoma Belamcandae, Radix Glycyrrhizae, has effect of heat-clearing and toxic substances removing, antiinflammatory, sterilization, and antagonism heat in blood poison is contained, and prevents pathological changes and the state of an illness aggravation of inflammation, slows down the various discomforts such as pruritus; The Multiple components such as Radix Adenophorae (Radix Glehniae), Radix Trichosanthis, Tiandong County, Radix Platycodonis, Radix Ophiopogonis, Rhizoma Polygonati Odorati, Bulbus Lilii, nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst, strong lung spleen, goes the heresy that wind-fire is damp and hot.Above plurality of Chinese composition suitably coordinates, and utilizes the collaborative or resistant function that it is mutual, and compatibility goes out better to play drug effect and the special medicine for cheilitis, lastingly evident in efficacy.

Use the present invention to treat the medicine of cheilitis, need not take medicine, liquid formulation or unguentum are directly applied to lip, play heat clearing away to greatest extent nourshing Yin and drynsessmoistening prescription, the effect of antipruritic dispelling wind, low production cost, preparation is simple, with rear comfortable, and through focus, good effect, instant effect, without any side effects, not easily recur after healing, patient is easy to accept, and greatly improves patient work and quality of life.

(4) detailed description of the invention

Below in conjunction with embodiment, the invention will be further described, but the present invention is not limited thereto.

Embodiment 1:

This is used for the treatment of the medicine of cheilitis, and its active component is made up of the raw material of following weight:

Olive oil 40g, Mel 8g, glycerol 16g, azone 3g, Tween 80 1g, diphenhydramine 1g; Carbamide 1g, retinol1 g, vitamin D1 g, vitamin e1 g, vitamin B12 1g; Middle medicated bag 12g;

The active component of described middle medicated bag is made up of the raw material of following weight:

Fructus Aurantii 9g, Medulla Tetrapanacis 10g, Fructus Cnidii 15g, Herba Asari 15g, Bulbus Fritillariae Cirrhosae 15g, Herba Spirodelae 12g, Radix Rehmanniae 20g, Fructus Forsythiae 20g, Radix Scrophulariae 20g, Flos Lonicerae 20g, Radix Adenophorae (Radix Glehniae) 15g, Radix Trichosanthis 15g, Radix Asparagi 15g, Radix Platycodonis 15g, Radix Ophiopogonis 15g, Rhizoma Polygonati Odorati 15g, Bulbus Lilii 30g, Rhizoma Belamcandae 10g, Radix Glycyrrhizae 6g.

This is used for the treatment of the preparation method of the medicine of cheilitis, adopts following steps:

A, the olive oil getting above-mentioned weight, Mel, glycerol, azone, Tween 80, diphenhydramine are mixed to get A bag, for subsequent use;

B, the carbamide getting above-mentioned weight, vitamin A, vitamin D, vitamin E, vitamin B12 are mixed to get B bag, for subsequent use;

C, get each taste Chinese medicine of above-mentioned weight, dry, pulverize, crossing 300 mesh sieves must mix Chinese medicinal powder, for subsequent use;

D, the ethanol adding 75% in the mixing Chinese medicinal powder of step c infiltrate 28h, then load in percolator, constantly add 75% alcoholic solution and carry out percolation, collect leachate, for subsequent use; Wherein, the weight of 75% total alcoholic solution that percolation process adds is 6 times of step c Chinese medicinal powder weight;

F, the B obtained by step b wrap and add in the obtained A bag of step a, and stir, then add the obtained the concentrated liquid of tradition Chinese medicine of step e, continuation stirring obtains mixed solution to evenly in 25 minutes;

G, the mixed solution heating in water bath obtained by step f, heating-up temperature 68 DEG C, heating 10min, to obtain final product.

Usage and dosage: respectively smear once in the morning, afternoon in the daytime, point is applied to affected part, lip portion; Smear before sleeping evening, applying amount is daytime 2 times of ampoule again.Anemia of pregnant woman is forbidden.

Embodiment 2:

Olive oil 35g, Mel 4g, glycerol 12g, azone 1g, Tween 80 0.5g, diphenhydramine 0.5g; Carbamide 0.5g, vitamin A 0.5g, vitamin D 0.5g, vitamin E 0.5g, vitamin B12 0.5g; Middle medicated bag 10g;

Fructus Aurantii 6g, Medulla Tetrapanacis 5g, Fructus Cnidii 10g, Herba Asari 10g, Bulbus Fritillariae Cirrhosae 10g, Herba Spirodelae 9g, Radix Rehmanniae 15g, Fructus Forsythiae 15g, Radix Scrophulariae 15g, Flos Lonicerae 15g, Radix Adenophorae (Radix Glehniae) 10g, Radix Trichosanthis 10g, Radix Asparagi 10g, Radix Platycodonis 10g, Radix Ophiopogonis 10g, Rhizoma Polygonati Odorati 10g, Bulbus Lilii 25g, Rhizoma Belamcandae 5g, Radix Glycyrrhizae 4g.

C, get each taste Chinese medicine of above-mentioned parts by weight, dry, pulverize, crossing 200 mesh sieves must mix Chinese medicinal powder;

D, the ethanol adding 75% in the mixing Chinese medicinal powder of step c infiltrate 24h, then load in percolator, constantly add 75% alcoholic solution and carry out percolation, collect leachate, for subsequent use; Wherein, the weight of 75% total alcoholic solution that percolation process adds is 5 times of step c Chinese medicinal powder weight;

F, the B obtained by step b wrap and add in the obtained A bag of step a, and stir, then add the obtained the concentrated liquid of tradition Chinese medicine of step e, continuation stirring obtains mixed solution to evenly in 20 minutes;

G, the mixed solution heating in water bath obtained by step f, heating-up temperature 65 DEG C, heating 15min, to obtain final product.

Usage and dosage, with embodiment 1, no longer describes in detail herein.

Embodiment 3:

Olive oil 45g, Mel 12g, glycerol 20g, azone 5g, Tween 80 2g, diphenhydramine 1.5g; Carbamide 1.5g, retinol1 .5g, vitamin D1 .5g, vitamin e1 .5g, vitamin B12 1.5g; Middle medicated bag 15g;

Fructus Aurantii 12g, Medulla Tetrapanacis 15g, Fructus Cnidii 20g, Herba Asari 20g, Bulbus Fritillariae Cirrhosae 20g, Herba Spirodelae 15g, Radix Rehmanniae 25g, Fructus Forsythiae 25g, Radix Scrophulariae 25g, Flos Lonicerae 25g, Radix Adenophorae (Radix Glehniae) 20g, Radix Trichosanthis 20g, Radix Asparagi 20g, Radix Platycodonis 20g, Radix Ophiopogonis 20g, Rhizoma Polygonati Odorati 20g, Bulbus Lilii 35g, Rhizoma Belamcandae 15g, Radix Glycyrrhizae 8g.

C, get each taste Chinese medicine of above-mentioned parts by weight, dry, pulverize, crossing 400 mesh sieves must mix Chinese medicinal powder;

D, the ethanol adding 75% in the mixing Chinese medicinal powder of step c infiltrate 30h, then load in percolator, constantly add 75% alcoholic solution and carry out percolation, collect leachate, for subsequent use; Wherein, the weight of 75% total alcoholic solution that percolation process adds is 7 times of step c Chinese medicinal powder weight;

G, the mixed solution heating in water bath obtained by step f, heating-up temperature 70 DEG C, heating 12min, to obtain final product.

Usage and dosage, with embodiment 1, no longer describes in detail herein.

Embodiment 4:

Olive oil 38g, Mel 6g, glycerol 14g, azone 2g, Tween 80 0.8g, diphenhydramine 0.6g; Carbamide 0.6g, vitamin A 0.6g, vitamin D 0.6g, vitamin E 0.6g, vitamin B12 0.6g; Middle medicated bag 11g;

Fructus Aurantii 8g, Medulla Tetrapanacis 7g, Fructus Cnidii 12g, Herba Asari 12g, Bulbus Fritillariae Cirrhosae 12g, Herba Spirodelae 10g, Radix Rehmanniae 16g, Fructus Forsythiae 16g, Radix Scrophulariae 16g, Flos Lonicerae 16g, Radix Adenophorae (Radix Glehniae) 12g, Radix Trichosanthis 12g, Radix Asparagi 12g, Radix Platycodonis 12g, Radix Ophiopogonis 13g, Rhizoma Polygonati Odorati 13g, Bulbus Lilii 27g, Rhizoma Belamcandae 8g, Radix Glycyrrhizae 5g.

Preparation method and usage and dosage, with embodiment 1, no longer describe in detail herein.

Embodiment 5:

Olive oil 42g, Mel 10g, glycerol 18g, azone 4g, Tween 80 1.5g, diphenhydramine 1.2g; Carbamide 1.2g, retinol1 .2g, vitamin D1 .2g, vitamin e1 .2g, vitamin B12 1.2g; Middle medicated bag 13g;

Fructus Aurantii 11g, Medulla Tetrapanacis 12g, Fructus Cnidii 18g, Herba Asari 17g, Bulbus Fritillariae Cirrhosae 18g, Herba Spirodelae 13g, Radix Rehmanniae 22g, Fructus Forsythiae 22g, Radix Scrophulariae 22g, Flos Lonicerae 22g, Radix Adenophorae (Radix Glehniae) 16g, Radix Trichosanthis 16g, Radix Asparagi 16g, Radix Platycodonis 16g, Radix Ophiopogonis 16g, Rhizoma Polygonati Odorati 16g, Bulbus Lilii 32g, Rhizoma Belamcandae 12g, Radix Glycyrrhizae 7g.

Preparation method and usage and dosage, with embodiment 2, no longer describe in detail herein.

Embodiment 6:

Olive oil 40g, Mel 8g, glycerol 16g, azone 3g, Tween 80 1g, diphenhydramine 1g; Carbamide 1g, retinol1 g, vitamin D1 g, vitamin e1 g, vitamin B12 1g; Middle medicated bag 12g; 13 parts, natural Cera Flava, quintessence oil 2 parts;

This is used for the treatment of the preparation method of the unguentum of cheilitis, adopts following steps:

C, get each taste Chinese medicine of above-mentioned parts by weight, dry, pulverize, crossing 300 mesh sieves must mix Chinese medicinal powder;

D, the ethanol adding 75% in the mixing Chinese medicinal powder of step c infiltrate 24h, then load in percolator, constantly add 75% alcoholic solution and carry out percolation, collect leachate, for subsequent use; Wherein, the weight of 75% total alcoholic solution that percolation process adds is 6 times of step c Chinese medicinal powder weight;

F, the B obtained by step b wrap and add in the obtained A bag of step a, and stir, then add the obtained the concentrated liquid of tradition Chinese medicine of step e, continuation stirring obtains mixed solution to evenly in 22 minutes;

G, the mixed solution heating in water bath that step f is obtained, heating-up temperature 65 DEG C, heating 10min, period adds the natural Cera Flava of above-mentioned parts by weight and dissolves completely; After having heated, add the quintessence oil of above-mentioned parts by weight, stir to obtain unguentum.

Usage and dosage: respectively smear once in the morning, afternoon in the daytime, applying amount is thin layer; Smear again before sleeping evening, applying amount be daytime ampoule 2-3 doubly.Anemia of pregnant woman is forbidden.

Embodiment 7:

Olive oil 35g, Mel 4g, glycerol 12g, azone 1g, Tween 80 0.5g, diphenhydramine 0.5g; Carbamide 0.5g, vitamin A 0.5g, vitamin D 0.5g, vitamin E 0.5g, vitamin B12 0.5g; Middle medicated bag 10g; Natural Cera Flava 10g, quintessence oil 1g;

G, the mixed solution heating in water bath that step f is obtained, heating-up temperature 70 DEG C, heating 15min, period adds the natural Cera Flava of above-mentioned parts by weight and dissolves completely; After having heated, add the quintessence oil of above-mentioned parts by weight, stir to obtain unguentum.

Usage and dosage, with embodiment 6, no longer describes in detail herein.

Embodiment 8:

Olive oil 45g, Mel 12g, glycerol 20g, azone 5g, Tween 80 2g, diphenhydramine 1.5g; Carbamide 1.5g, retinol1 .5g, vitamin D1 .5g, vitamin e1 .5g, vitamin B12 1.5g; Middle medicated bag 15g; Natural Cera Flava 16g, quintessence oil 3g;

D, the ethanol adding 75% in the mixing Chinese medicinal powder of step c infiltrate 26h, then load in percolator, constantly add 75% alcoholic solution and carry out percolation, collect leachate, for subsequent use; Wherein, the weight of 75% total alcoholic solution that percolation process adds is 5 times of step c Chinese medicinal powder weight;

G, the mixed solution heating in water bath that step f is obtained, heating-up temperature 70 DEG C, heating 12min, period adds the natural Cera Flava of above-mentioned parts by weight and dissolves completely; After having heated, add the quintessence oil of above-mentioned parts by weight, stir to obtain unguentum.

Usage and dosage, with embodiment 6, no longer describes in detail herein.

Embodiment 9:

Olive oil 38g, Mel 6g, glycerol 14g, azone 2g, Tween 80 0.8g, diphenhydramine 0.6g; Carbamide 0.6g, vitamin A 0.6g, vitamin D 0.6g, vitamin E 0.6g, vitamin B12 0.6g; Middle medicated bag 11g; Natural Cera Flava 11g, quintessence oil 1.5g;

Preparation method and usage and dosage, with embodiment 6, no longer describe in detail herein.

Embodiment 10:

Olive oil 42g, Mel 10g, glycerol 18g, azone 4g, Tween 80 1.5g, diphenhydramine 1.2g; Carbamide 1.2g, retinol1 .2g, vitamin D1 .2g, vitamin e1 .2g, vitamin B12 1.2g; Middle medicated bag 13g; Natural Cera Flava 15g, quintessence oil 2.5g;

Preparation method and usage and dosage, with embodiment 7, no longer describe in detail herein.

Adopt unguentum of the present invention to treat patient 512 example altogether, except 19 example recurrences also abandoning cure, within the equal 3-4 of other patients days, cure.Effective percentage 100%, cure rate is up to 96.3%.

Model case:

1, Wei, female, 26 years old, student, pain is on tenterhooks, difficulty falling asleep, and lower flaps, very itches unbearably, and doctor trained in Western medicine multi-treatment is not good, is coated with and uses this unguentum, and painting is stood by one day sufferings and disappeared, and is coated with morning and sees rotten taking off evening; 3rd, swollen disappearing was recovered.Follow up a case by regular visits to March without recurrence.

2, Cai, female, 34 years old, lawyer, red lip district extensive edema, congested, rotten to the corn, weight repeatedly, was coated with this unguentum and cures for 3rd, follow up a case by regular visits to March without recurrence.

3, permitted certain, man, 40 years old, outwork person, long-term receipt ultraviolet radiation, dust storm are attacked, and dry lip desquamation is without skin, and violent pruritus, treats by this unguentum usage and dosage, and the same day fully recovers.Follow up a case by regular visits to February without recurrence.

4, Lee, man, 39 years old, self-employed entrepreneurs, long-term alcohol, lower lip is red and swollen, and white is rotten to the corn; Hurt like hell, is coated with this unguentum and cures for 4th, follow up a case by regular visits to March without recurrence.

5, beam, 29 years old, actor, long term frequent was made up, makeup removing, lower lip desquamation, and squama, removes ornaments and formal dress, washes one's face, pain of having dinner, and is coated with and within 3rd, cures with this unguentum, follow up a case by regular visits to March without recurrence.

Claims

1. be used for the treatment of a medicine for cheilitis, it is characterized in that: its active component is made up of the raw material of following parts by weight:

2. a kind of medicine being used for the treatment of cheilitis according to claim 1, is characterized in that: also comprise natural Cera Flava 10-16 part, quintessence oil 1-3 part.

3. a kind of medicine being used for the treatment of cheilitis according to claim 1, is characterized in that: its active component is made up of the raw material of following parts by weight:

4. a kind of medicine being used for the treatment of cheilitis according to claim 2, is characterized in that: its active component is made up of the raw material of following parts by weight:

5. be used for the treatment of a preparation method for the medicine of cheilitis as claimed in claim 1, it is characterized in that: comprise following operating procedure:

6. be used for the treatment of a preparation method for the medicine of cheilitis as claimed in claim 2, it is characterized in that: comprise following operating procedure: