CN104771733B - A kind of Chinese medicine composition for treating chronic bronchitis - Google Patents

Abstract

The invention discloses a kind of technical field for being used to treat the Chinese medicine composition of chronic bronchitis, belonging to the medicine for the treatment of chronic bronchitis.The composition of the present invention includes：Chinese ephedra 8 12, rhizoma zingiberis 8 12, radix glycyrrhizae 8 12, balloonflower root 8 12, Pi are parts by weight above leaf 8 12, aster 8 12, tussilago 8 12, great burdock achene 8 12, lily 8 12, Radix Angelicae Sinensis 8 12, cassia twig 8 12, peppermint 8 12, the tuber of pinellia 8 12, the windproof 8 12, root bark of white mulberry 8 12, asarum 8 12, the fruit of Chinese magnoliavine 8 12, the root of herbaceous peony 8 12, birthwort 8 12, the bighead atractylodes rhizome 8 12, radix scutellariae 48, the coptis 48, the capsule of weeping forsythia 48, Snakegourd Fruit 8 12, caulis bambusae in taenian 48, Folium Elaeagni 8 12, old caulis perllae 8 12, tip or stalactite 8 12.Medicine source wide coverage of the present invention, full-featured, compatibility science is quick, has no toxic side effect, does not recur.

Description

A kind of Chinese medicine composition for treating chronic bronchitis

Technical field

The invention belongs to the technical field for the medicine for treating chronic bronchitis, particularly relates to one kind and treats chronic bronchial Scorching Chinese medicine composition.

Background technology

Respiratory disease accounts for a quarter of internal medicine disease, in China human mortality statistics, respiratory disease first The position cause of the death.Due to atmosphere pollution, smoking, infection, intolerance factors, climate change, the aging of social crowd structure, illness rate occupies Height, and it is many by the slow branch of anxious branch turn, frequently result in chronic impairment of pulmonary function or even disable, chronic bronchitis is medical science hardly possible Topic.

Chronic bronchitis（chronic bronchitis）It is the chronic non-of trachea-bronchial epithelial cell mucous membrane and its surrounding tissue Specific inflammatory.Clinically continue 3 months every year, continuously as cardinal symptom using cough, expectoration or with recurrent exerbations such as asthma More than 2 years.Early symptom is slight, and more than winter attack, spring and summer is alleviated.Late period can exist throughout the year because of increased inflammation, symptom.Its disease Feature of science is that bronchus glandular hyperplasia and mucous membrane secretion increase.The state of an illness is in progress in slow progressive, the obstructive lung qi of Chang Bingfa Swollen, pulmonary hypertension, or even cor pulmonale often occur for severe patient, drastically influence the labour of people.

Treatment for chronic bronchitis, at present, Western medicine often with anti-inflammatory, relieving asthma, expand the medicines such as tracheae medicine, hormone drug Treatment, these Western medicine can only play certain control action to the sick acute attack, and its side effect is big, only takes stopgap measures and does not control This.Traditional Chinese medical science staff and scholar also develop the Chinese herbal medicine of some medical chronic bronchitis, and these Chinese herbal medicines are due to raw material The problem of selection of medicine and compatibility, its, slowly effect poor to treatment of chronic bronchitis effect, caused to patients ' psychological very big Burden.

The content of the invention

The present invention provides a kind of Chinese medicine composition for being used to treat treatment chronic bronchitis, solves and controls in the prior art The drug side-effect for the treatment of chronic bronchitis is big, slowly effect and the problem of easily recur.

A kind of Chinese medicine composition for treating chronic bronchitis of the present invention, it is mainly subject to by the following technical programs Realize：

The Chinese medicine composition of the present invention, including the raw material of following parts by weight are made：It is Chinese ephedra 8-12 parts, rhizoma zingiberis 8-12 parts, sweet Careless 8-12 parts, balloonflower root 8-12 parts, Pi are leaf 8-12 parts, aster 8-12 parts, tussilago 8-12 parts, great burdock achene 8-12 parts, lily 8- 12 parts, Radix Angelicae Sinensis 8-12 parts, cassia twig 8-12 parts, peppermint 8-12 parts, tuber of pinellia 8-12 parts, windproof 8-12 parts, root bark of white mulberry 8-12 parts, asarum 8-12 parts, fruit of Chinese magnoliavine 8-12 parts, root of herbaceous peony 8-12 parts, birthwort 8-12 parts, bighead atractylodes rhizome 8-12 parts, radix scutellariae 4-8 parts, coptis 4-8 parts, company Stick up 4-8 parts, Snakegourd Fruit 8-12 parts, caulis bambusae in taenian 4-8 parts, Folium Elaeagni 8-12 parts, old caulis perllae 8-12 parts, tip or stalactite 8-12 parts.

The present invention by including Chinese ephedra, rhizoma zingiberis, radix glycyrrhizae, balloonflower root, loguat leaf, aster, tussilago, great burdock achene, lily, Radix Angelicae Sinensis, Cassia twig, peppermint, the tuber of pinellia, the windproof, root bark of white mulberry, asarum, the fruit of Chinese magnoliavine, the root of herbaceous peony, birthwort, the bighead atractylodes rhizome, radix scutellariae, the coptis, the capsule of weeping forsythia, Snakegourd Fruit, At least 28 taste herbal raw materials including caulis bambusae in taenian, Folium Elaeagni, old caulis perllae and tip or stalactite are formulated, its broad covered area, work( Can comprehensively, compatibility is scientific and reasonable；By comprehensive conditioning to the spleen of human body, stomach, lung, the heart, liver, courage, intestines and bladder, reach only The effect of cloudy, complement drives wind, clearing away the heart fire and tranquillizing, invigorating the spleen are reinforced the kidney, is held back in cloperastine asthma, regulating qi-flowing for eliminating phlegm, clearing heat and detoxicating, blood-nourishing, while also has Strengthen the effect of body immunity, can fundamentally cure chronic bronchitis；Using righting as this, using eliminating evil as mark, so as to The purpose treated both principal and secondary aspect of disease is reached.

In the Chinese medicine composition of the present invention, Chinese ephedra：The pungent, slight bitter of property, taste temperature；Return lung, bladder warp；With sweating cold dispelling, a surname The effect of lung is relievingd asthma, inducing diuresis for removing edema；Anemofrigid cold is cured mainly, uncomfortable in chest to breath with cough, geomantic omen edema, bronchial astehma.

In the Chinese medicine composition of the present invention, rhizoma zingiberis：Acrid flavour, property heat；Returns spleen, stomach, the heart, lung channel；With warming spleen and stomach for dispelling cold, Hui Yang Promote blood circulation, eliminating dampness dissolving phlegm, Wenfei of drink the effect of；Coldness and pain in the epigastrium is cured mainly, is vomitted, diarrhea, yang depletion is fainted inverse, and cold drink is breathed with cough, cold-dampness numbness Bitterly.

In the Chinese medicine composition of the present invention, radix glycyrrhizae：Nature and flavor, it is sweet, put down；Enter spleen, stomach, lung channel；With invigorate the spleen and benefit qi, emergency is stopped Bitterly, the effect of growing cough moistening lung, emergency removing toxic substances；Cure mainly the thin face Huang of burnout deficiency of food, flesh, palpitation, stomachache loose stool, four limbs contraction suddenly pain Bitterly, hysteria, cough gather asthma, abscess of throat, ulcerative carbuncle swelling and pain.

In the Chinese medicine composition of the present invention, balloonflower root：Bitter, pungent, slightly warm in nature；Enter lung channel；With expelling phlegm and arresting coughing, and there is a surname The effect of lung, apocenosis；Cure mainly coughing with a lot of sputum, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache, aphthae, hot eyes Swelling and pain, uroschesis.

In the Chinese medicine composition of the present invention, loguat leaf：Bitter, micro-pungent, cold nature；Attach to the lung and stomach meridians；With antibechic, eliminating the phlegm, Relieving asthma and the effect of antibacterial；Cough with lung heat is cured mainly, circulation of vital energy in the wrong direction asthma is anxious, gastropyretic vomiting, hiccup.

In the Chinese medicine composition of the present invention, aster：It is warm-natured, it is bitter, pungent, sweet；Return lung passes through；With moistening lung to lower qi, resolving sputum stops The effect of cough；Cough is cured mainly, deficiency syndrome of the lung overstrain cough, consumptive lung disease lung carbuncle, cough vomiting of pus and blood, difficult urination, is breathed with cough for abundant expectoration, new chronic cough is coughed, Overstrain cough hemoptysis.

In the Chinese medicine composition of the present invention, tussilago：It is acrid flavour, warm-natured；Return lung passes through；With gas, profit under preventing phlegm from forming and stopping coughing, antibechic The function of lung eliminating the phlegm；Cough is cured mainly, is panted, consumptive lung disease, cough is spat the diseases such as blood.

In the Chinese medicine composition of the present invention, great burdock achene：Acrid flavour, hardship, it is cold in nature；Attach to the lung and stomach meridians；With dispelling wind and heat from the body, heat-clearing Removing toxic substances promoting eruption, facilitaing lung relieving sore-throat dissipate the effect of swollen；Anemopyretic cold, warm disease are cured mainly from the beginning of wind-heat or cough with lung heat, not smooth, pharynx of coughing up phlegm Larynx swells and ache, and macula is impermeable, and measles initial stage, rash goes out not smooth and rubella itch, sore swollen toxin and mumps etc..

In the Chinese medicine composition of the present invention, lily：It is sweet, cold nature；The thoughts of returning home, lung channel；With Yin nourishing and lung moistening, moistening lung stops Cough, the effect of clearing away the heart fire and tranquillizing；Cure mainly yin chronic cough, blood-stained sputum, dysphoria palpitates with fear, insomnia and dreamful sleep is absent-minded.

In the Chinese medicine composition of the present invention, Radix Angelicae Sinensis：It is sweet, pungent, bitter, warm-natured；Return liver, the heart, the spleen channel；With replenishing and activating blood, Menstruction regulating and pain relieving, the effect of relaxing bowel；Cure mainly the poly- all cards of the deficiency of blood, irregular menstruation, Amenorrhea, dysmenorrhoea, abdominal mass knot, uterine bleeding, cold of insufficiency type abdomen Bitterly, Impotence numbness, numbness, intestines are dry and shit is difficult, weight, ulcer sores, injury from falling down after dysentery characterized by blood in the stool.

In the Chinese medicine composition of the present invention, cassia twig：Pungent, sweet, the tepor of property；The thoughts of returning home, lung, bladder warp；With sweating expelling pathogenic factors from muscles and skin, Warming meridians and promoting circulation of qi, helps yang transforming qi, the effect of eliminating cold to stop pain；Cure mainly exterior syndrome due to wind-cold, numbness and ache of cold dampness, peripheral coldness, closed dysmenorrhea, abdominal mass Caking, the obstruction of qi in the chest, palpitaition, phlegm and retained fluid, difficult urination.

In the Chinese medicine composition of the present invention, peppermint：Property is pungent, and taste is cool；Enter lung channel, Liver Channel；With dispelling wind and heat from the body, clear sharp head The effect of mesh, relieving sore-throat promoting eruption, soothing the liver promoting the circulation of qi；Dispelling wind is cured mainly, radiates, ward off dirty, removing toxic substances, affection of exogenous wind-heat, headache, abscess of throat, food Stagnant gas is swollen, aphtha, toothache, sore scabies, urticaria, warm disease from the beginning of, rubella itch, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest.

In the Chinese medicine composition of the present invention, the tuber of pinellia：Pungent, the taste temperature of property；Enter spleen, stomach；With eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, The effect of dissolving lump and resolving mass；Externally used detumescence relieves pain；Cure mainly hot phlegm, vomiting, the card of wind phlegm.

It is windproof in the Chinese medicine composition of the present invention：Acrid flavour, sweet, slightly warm in nature；Return bladder, liver, the spleen channel；With expel pathogenic wind from the body surface, Expel endogenous wind to relieve convulsion, stop the effect of convulsion is jerked surely；Cure mainly diseases caused by external factors exterior syndrome, rubella itch, arthralgia pain due to rheumatism, lockjaw.

In the Chinese medicine composition of the present invention, the root bark of white mulberry：It is sweet, cold in nature；Enter lung channel；With removing heat from lung and relieving asthma, inducing diuresis for removing edema, repair The effect of multiple scar；Cure mainly the diseases such as lung heat cough and asthma, the edema of the face, difficult urination.

In the Chinese medicine composition of the present invention, asarum：Acrid flavour, it is warm-natured；The thoughts of returning home, lung, kidney channel；Relieved pain with expelling wind and clearing away cold, temperature The effect of lungization drink is sensible；Cure mainly catch cold, have a headache, having a toothache, chill temperature numbness, phlegm and retained fluid cough and asthma, nasal obstruction nasosinusitis, eye of wind mesh screen, Ear closes pharyngalgia, aphtha halitosis.

In the Chinese medicine composition of the present invention, the fruit of Chinese magnoliavine：It is sweet, sour, it is warm-natured；Enter lung, kidney, the heart channel of Hang-Shaoyin；With nourishing generate fluid, mend Kidney nourishing heart, restrains the effect of astringent or styptic treatment for spontaneous sweating；Cure mainly deficiency of vital energy Tianjin wound, the tired hidrosis of body, palpitaition of losing heart；Caused by insufficiency of lung-QI,deficiency of lung-QI or deficiency of both the lung and kidney Breath with cough, or breath with cough with the passing of time, lung qi consumption wound；Insufficiency of heart yin, palpitation and severe palpitation, insomnia forgetfulness；The unconsolidation of the kidney-qi, seminal emission, frequent micturition, or spleen kidney Two is empty, endless diarrhea.

In the Chinese medicine composition of the present invention, the root of herbaceous peony：Bitter, acid, it is slightly cold；Return liver, the spleen channel；The moon is held back with blood-nourishing, soft liver is stopped Bitterly, the effect of suppressing liver-YANG；Liver-blood deficiency and deficiency of blood irregular menstruation are cured mainly, the chest side of body epigastric pain or four limbs contraction of incoordination between the liver and the spleen are anxious Pain, the dizziness of having a headache of liver-yang hyperactivity.

In the Chinese medicine composition of the present invention, birthwort：Bitter, it is slightly cold；Return lung, large intestine channel；With clearing lung-heat sending down abnormally ascending, cough-relieving is put down Asthma, gut purge disappear hemorrhoid the effect of；Cure mainly dyspnea and cough due to lung-heat, blood-stained sputum, the hot hemorrhoid blood of intestines, hemorrhoid gall.

In the Chinese medicine composition of the present invention, the bighead atractylodes rhizome：It is bitter, sweet, it is warm-natured；Returns spleen, stomach；With strengthening the spleen and replenishing qi, eliminating dampness profit Water, hidroschesis, it is antiabortive the effect of；Cure mainly spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability.

In the Chinese medicine composition of the present invention, radix scutellariae：Bitter, it is cold in nature；Return lung, courage, spleen, large intestine, small intestinl channel；It is dry with heat-clearing Wet, purging intense heat and detonicating, hemostasis is antiabortive, the effect of hypotensive；Cure mainly damp-warm syndrome, heat temperature evil of vomitting uncomfortable in chest, damp and hot feeling of fullness, rush down dysentery, jaundice, Cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, fetal irritability.

In the Chinese medicine composition of the present invention, the coptis：Bitter, it is cold in nature；The thoughts of returning home, spleen, stomach, liver, courage, large intestine channel；With heat-clearing Eliminating dampness, the effect of purging intense heat and detonicating；Cure mainly damp and hot feeling of fullness, vomit acid regurgitation, rush down dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, it is vexed not Sleep, blood-head tells nosebleed, hot eyes, toothache, quench one's thirst, carbuncle swells furunculosis；Eczema, wet sore are controlled outside, duct is suppurated.

In the Chinese medicine composition of the present invention, the capsule of weeping forsythia：Cold nature, bitter；Enter lung channel, the heart channel of Hang-Shaoyin, gallbladder channel, Liver Channel；With heat-clearing Removing toxic substances, the effect of carbuncle that disappears dissipating bind；Cure mainly affection of exogenous wind-heat, warm disease heating, sore swell and ache curative, scrofula.

In the Chinese medicine composition of the present invention, Snakegourd Fruit：Sweetness and bitterness, it is cold in nature；Enter lung, stomach, large intestine channel；With moistening lung, resolving sputum, dissipate Knot, ease constipation, control phlegm-heat cough, the obstruction of qi in the chest, accumulation of pathogens in chest, consumptive lung disease hemoptysis, quench one's thirst, jaundice, constipation, carbuncle swells from the beginning of the effect of；Cure mainly lung heat Cough, the turbid Huang of phlegm is thick, chest impediment and cardialgia, acute mastitis, lung carbuncle, acute appendicitis swelling and pain.

In the Chinese medicine composition of the present invention, caulis bambusae in taenian：Cold nature, it is sweet；Enter lung, stomach, gallbladder channel；With clearing heat and stopping vomiting, phlegm is washed Open it is strongly fragrant, the effect of antiabortive cool blood；Cough with lung heat, dysphoria with smothery sensation palpitation with fear are cured mainly, stomach energy is vomitted oh, pernicious vomiting, fetal irritability, spitted blood, nosebleed Blood, hematuria, uterine bleeding.

In the Chinese medicine composition of the present invention, Folium Elaeagni：It is sour, it is mild-natured；Enter lung channel；The effect of with convergence cough-relieving；Cure mainly The diseases such as cough due to deficiency of the lung, asthma.

In the Chinese medicine composition of the present invention, old caulis perllae：Acrid flavour, it is warm-natured；Return lung, the spleen channel；With regulating the flow of QI to ease the stomach, relieve pain, peace The effect of tire；It is vexed to cure mainly chest diaphragm ruffian, gastral cavity pain, belch vomiting, fetal irritability.

In the Chinese medicine composition of the present invention, tip or stalactite：It is sweet, it is salty, it is warm-natured；Enter lung, kidney, stomach；With warm lung, establishing-Yang, The effect of promoting lactation；Cure mainly lung cold to cough long, consumptive disease cough and asthma, impotence and premature ejaculation, emission, cold arthralgia of loins and legs, alactation.

Preferably, Chinese medicine composition of the invention, including the raw material of following parts by weight are made：10 parts of Chinese ephedra, 10 parts of rhizoma zingiberis, 10 parts of radix glycyrrhizae, 10 parts of balloonflower root, Pi are 10 parts of leaf, 10 parts of aster, 10 parts of tussilago, 10 parts of great burdock achene, 10 parts of lily, Radix Angelicae Sinensis 10 Part, 10 parts of cassia twig, 10 parts of peppermint, 10 parts of the tuber of pinellia, windproof 10 parts, 10 parts of the root bark of white mulberry, 10 parts of asarum, 10 parts of the fruit of Chinese magnoliavine, the root of herbaceous peony 10 It is part, 10 parts of birthwort, 10 parts of the bighead atractylodes rhizome, 6 parts of radix scutellariae, 6 parts of the coptis, 6 parts of the capsule of weeping forsythia, 10 parts of Snakegourd Fruit, 6 parts of caulis bambusae in taenian, 10 parts of Folium Elaeagni, old 10 parts of caulis perllae, 10 parts of tip or stalactite.

The Chinese medicine composition medicine source of the present invention is more, and cheap to be easy to get, drug effect complements each other, focus depths of going directly, to people Internal portion function carries out thoroughly comprehensive conditioning.The Chinese medicine composition mild in medicine property and, have no toxic side effect, wide adaptation range, tool Play the role of short treating period, it is quick, do not recur, realize the purpose for the treatment of a disease by looking into both its root cause and symptoms, significantly reduce patient's economy and psychology is born Load.According to clinical verification, the cure rate of traditional Chinese medicine composition for treating chronic bronchitis of the invention is high, and total effective rate is up to 98%, drug effect It is stable.

Specifically, in Chinese medicine composition of the invention, the formulation of the Chinese medicine composition is decoction, pill, granule, glue One kind in wafer or tablet.Its preparation method is simple, easily controllable, is easy to implement industrialization.Patient can according to oneself Health and living condition, decoction, pill, granule, capsule or tablet are taken in selection, convenient to take.

The usage of the Chinese medicine composition of the present invention：Daily once in the morning and once at night, take within 1 hour after meal, one week is a course for the treatment of.

Beneficial effects of the present invention：The present invention is in Chinese ephedra, rhizoma zingiberis, radix glycyrrhizae, balloonflower root, loguat leaf, aster, tussilago, burdock Son, lily, Radix Angelicae Sinensis, cassia twig, peppermint, the tuber of pinellia, the windproof, root bark of white mulberry, asarum, the fruit of Chinese magnoliavine, the root of herbaceous peony, birthwort, the bighead atractylodes rhizome, radix scutellariae, Huang Under this 28 taste herbal raw material scientific compatibility of company, the capsule of weeping forsythia, Snakegourd Fruit, caulis bambusae in taenian, Folium Elaeagni, old caulis perllae and tip or stalactite, disease of going directly Stove depths, by carrying out system and comprehensive conditioning to the spleen of human body, stomach, lung, the heart, liver, courage, intestines and bladder, cough-relieving is reached Relieving asthma, regulating qi-flowing for eliminating phlegm, clearing heat and detoxicating, blood-nourishing hold back the effect of cloudy, complement drives wind, clearing away the heart fire and tranquillizing, invigorating the spleen are reinforced the kidney, while also have and increase The effect of strong body immunity, can fundamentally cure chronic bronchitis, realize the purpose for the treatment of a disease by looking into both its root cause and symptoms；Its course for the treatment of Short, quick, cure rate is high, and total effective rate efficacy stability, does not recur, had no toxic side effect, significantly reduce patient's warp up to 98% Ji and psychological burden.

Embodiment

Technical scheme is clearly and completely described below in conjunction with specific embodiment, it is clear that described Embodiment be only part of the embodiment of the present invention, rather than whole embodiment.Based on the embodiment in the present invention, ability The every other embodiment that domain those of ordinary skill is obtained under the premise of creative work is not made, belongs to guarantor of the present invention The scope of shield.

A kind of Chinese medicine composition for treating chronic bronchitis, including the raw material of following parts by weight are made：Chinese ephedra 8-12 parts, Rhizoma zingiberis 8-12 parts, radix glycyrrhizae 8-12 parts, balloonflower root 8-12 parts, Pi are leaf 8-12 parts, aster 8-12 parts, tussilago 8-12 parts, great burdock achene 8-12 parts, lily 8-12 parts, Radix Angelicae Sinensis 8-12 parts, cassia twig 8-12 parts, peppermint 8-12 parts, tuber of pinellia 8-12 parts, windproof 8-12 parts, Sang Bai Skin 8-12 parts, asarum 8-12 parts, fruit of Chinese magnoliavine 8-12 parts, root of herbaceous peony 8-12 parts, birthwort 8-12 parts, bighead atractylodes rhizome 8-12 parts, radix scutellariae 4-8 Part, coptis 4-8 parts, capsule of weeping forsythia 4-8 parts, Snakegourd Fruit 8-12 parts, caulis bambusae in taenian 4-8 parts, Folium Elaeagni 8-12 parts, old caulis perllae 8-12 parts, tip or stalactite 8-12 parts.

Further, Chinese medicine composition of the invention, including the raw material of following parts by weight are made：10 parts of Chinese ephedra, rhizoma zingiberis 10 Part, 10 parts of radix glycyrrhizae, 10 parts of balloonflower root, Pi are 10 parts of leaf, 10 parts of aster, 10 parts of tussilago, 10 parts of great burdock achene, 10 parts of lily, Radix Angelicae Sinensis 10 parts, 10 parts of cassia twig, 10 parts of peppermint, 10 parts of the tuber of pinellia, windproof 10 parts, 10 parts of the root bark of white mulberry, 10 parts of asarum, 10 parts of the fruit of Chinese magnoliavine, the root of herbaceous peony 10 parts, 10 parts of birthwort, 10 parts of the bighead atractylodes rhizome, 6 parts of radix scutellariae, 6 parts of the coptis, 6 parts of the capsule of weeping forsythia, 10 parts of Snakegourd Fruit, 6 parts of caulis bambusae in taenian, 10 parts of Folium Elaeagni, Old 10 parts of caulis perllae, 10 parts of tip or stalactite.

Further, in Chinese medicine composition of the invention, the formulation of the Chinese medicine composition is decoction, pill, particle One kind in agent, capsule or tablet.

Embodiment one

A kind of Chinese medicine composition for treating chronic bronchitis, including following raw material：Chinese ephedra 8g, rhizoma zingiberis 8g, radix glycyrrhizae 8g, tangerine Obstruct 8g, Pi leaf 8g, aster 8g, tussilago 8g, great burdock achene 8g, lily 8g, Radix Angelicae Sinensis 8g, cassia twig 8g, peppermint 8g, tuber of pinellia 8g, anti- Wind 8g, root bark of white mulberry 8g, asarum 8g, fruit of Chinese magnoliavine 8g, root of herbaceous peony 8g, birthwort 8g, bighead atractylodes rhizome 8g, radix scutellariae 4g, coptis 4g, capsule of weeping forsythia 4g, melon Beach wormwood 8g, caulis bambusae in taenian 4g, Folium Elaeagni 8g, old caulis perllae 8g, tip or stalactite 8g.

1500mL water is added in above-mentioned raw materials, is decocted, seethes with excitement after 30min, pours out decoction liquor；Remaining filter residue is continued Add water to cook, decoct 3 times altogether；Decoction liquor is merged, is concentrated into 100mL；It is divided into twice, respectively takes 50mL sooner or later, after meal 1h Take, one week is a course for the treatment of.

Embodiment two

A kind of Chinese medicine composition for treating chronic bronchitis, including following raw material：Chinese ephedra 10g, rhizoma zingiberis 10g, radix glycyrrhizae 10g, balloonflower root 10g, Pi are leaf 10g, aster 10g, tussilago 10g, great burdock achene 10g, lily 10g, Radix Angelicae Sinensis 10g, cassia twig 10g, thin Lotus 10g, tuber of pinellia 10g, windproof 10g, root bark of white mulberry 10g, asarum 10g, fruit of Chinese magnoliavine 10g, root of herbaceous peony 10g, birthwort 10g, bighead atractylodes rhizome 10g, Radix scutellariae 6g, coptis 6g, capsule of weeping forsythia 6g, Snakegourd Fruit 10g, caulis bambusae in taenian 6g, Folium Elaeagni 10g, old caulis perllae 10g, tip or stalactite 10g.

By above-mentioned raw materials attrition grinding, it is well mixed, pill is made, is 2g per ball weight, each taking 2 balls, daily 2 Secondary, 1h takes after meal, and one week is a course for the treatment of.

Embodiment three

A kind of Chinese medicine composition for treating chronic bronchitis, including following raw material：Chinese ephedra 12g, rhizoma zingiberis 12g, radix glycyrrhizae 12g, balloonflower root 12g, Pi are leaf 12g, aster 12g, tussilago 12g, great burdock achene 12g, lily 12g, Radix Angelicae Sinensis 12g, cassia twig 12g, thin Lotus 12g, tuber of pinellia 12g, windproof 12g, root bark of white mulberry 12g, asarum 12g, fruit of Chinese magnoliavine 12g, root of herbaceous peony 12g, birthwort 12g, bighead atractylodes rhizome 12g, Radix scutellariae 8g, coptis 8g, capsule of weeping forsythia 8g, Snakegourd Fruit 12g, caulis bambusae in taenian 8g, Folium Elaeagni 12g, old caulis perllae 12g, tip or stalactite 12g.

Above-mentioned raw materials are added into water, soaked, are distilled, are concentrated, spray drying, granule is made, often packs 2g, each taking 1 bag, 1h takes after meal, and 2 times a day, one week is a course for the treatment of.

Example IV

A kind of Chinese medicine composition for treating chronic bronchitis, including following raw material：Chinese ephedra 9g, rhizoma zingiberis 11g, radix glycyrrhizae 9g, Balloonflower root 9g, Pi are leaf 11g, aster 11g, tussilago 11g, great burdock achene 11g, lily 9g, Radix Angelicae Sinensis 9g, cassia twig 9g, peppermint 11g, half Summer 11g, windproof 11g, root bark of white mulberry 9g, asarum 9g, fruit of Chinese magnoliavine 11g, root of herbaceous peony 9g, birthwort 11g, bighead atractylodes rhizome 11g, radix scutellariae 5g, the coptis 5g, capsule of weeping forsythia 7g, Snakegourd Fruit 11g, caulis bambusae in taenian 7g, Folium Elaeagni 11g, old caulis perllae 9g, tip or stalactite 9g.

Above-mentioned raw materials are soaked, distilled, are concentrated, are dried, loads capsule, is made capsule, every capsule weight 0.75g, often Secondary to take 4,1h takes after meal, and 2 times a day, one week is a course for the treatment of.

Embodiment five

A kind of Chinese medicine composition for treating chronic bronchitis, including following raw material：Chinese ephedra 11g, rhizoma zingiberis 9g, radix glycyrrhizae 11g, Balloonflower root 11g, Pi are leaf 9g, aster 9g, tussilago 9g, great burdock achene 9g, lily 11g, Radix Angelicae Sinensis 11g, cassia twig 11g, peppermint 9g, the tuber of pinellia 9g, windproof 9g, root bark of white mulberry 11g, asarum 11g, fruit of Chinese magnoliavine 9g, root of herbaceous peony 11g, birthwort 9g, bighead atractylodes rhizome 9g, radix scutellariae 7g, coptis 7g, company Stick up 5g, Snakegourd Fruit 9g, caulis bambusae in taenian 5g, Folium Elaeagni 9g, old caulis perllae 11g, tip or stalactite 11g.

Above-mentioned raw materials are soaked, distilled, are concentrated, drying, tabletting, tablet are made, every weighs 1g, each taking 2, after meal 1h takes, and 2 times a day, one week is a course for the treatment of.

The present invention is expanded on further with reference to specific test example, wherein, include the present invention Chinese medicine composition animal Toxicity test, pharmacodynamics test and clinical observation experiment.

Animal toxicity test

The embodiment of the present invention one is arrived to the Chinese medicine composition of embodiment five, has carried out multiple animal toxicity test respectively, is wrapped Include the experiment under Various Seasonal and different geographical；Under the conditions of each season and Different climate, such as north of China, south, east Portion and western part are tested respectively；Every time during experiment, rabbit 30 is taken, male and female dual-purpose, body weight 1.8-2.2kg, is divided into two groups, often Group 15, one of which is overdose test group, and another group is normal amount test group, and overdose test group dosage is 6.0g/kg, Normal amount test group dosage is 2.0g/kg, and administering mode is administration by gavage administration, once in the morning and once at night, continuously takes 10 days, often Its observation administration reaction；Test of many times result shows that two groups of rabbit spirit, activity, diet, excretion are normal；Cut open inspection, naked eyes Examine main inside internal organs, no abnormality seen；Therefore, the Chinese medicine composition is without bad toxic side effect.

Animal pharmacodynamics test

Effect of the Chinese medicine composition of the present invention to chronic bronchitis model mouse.

Method：The ICR mouse 80 that body weight is 20-25g are taken, male and female half and half, 8 groups is randomly divided into, every group 10, is respectively The embodiment of the present invention one to the administration group of embodiment five, certain commercially available treatment Chinese medicine administration group of chronic bronchitis, model group and Control group；Carry out modeling respectively to preceding 7 groups of mouse, every group of animal is daily with 1% SO₂Stimulate, totally 20 days, then, stop SO₂ Stimulate, observe 10 days；Start packet administration while modeling, model group is not administered, the daily gavage physiological saline of control group.Give During medicine, situations such as observing each group animal activity diet, last time puts to death mouse after 2h is administered, and mouse bronchial is taken out in dissection Fixed, specimens paraffin embedding slices, H-E dyeing microscopic examinations, as a result examined with t with 10% formalin solution with lungs.

Ordinary circumstance：Normal group mouse spirit is good, agile strong, ingests normal, hair Mi Ze；Model group mouse Spirit is poor, tired sleeping deficiency of food, pants endlessly, hair is into bar without pool；Five groups of administration groups of the present invention, start to recover, 10 days extensive after 7 days It is multiple normal；The Chinese medicine group of certain commercially available treatment chronic bronchitis, starts to recover after 12 days, recovers within 15 days normal；Therefore, it is of the invention Chinese medicine composition it is more commercially available certain treatment chronic bronchitis Chinese medicine there is obvious advantage.

Pathological change：Table 1 lists different pharmaceutical to chronic bronchitis model mouse bronchial, Pulmonary lesions shadow Loud experimental result, as can be seen from Table 1, of the invention five groups of administration groups can very significantly mitigate SO₂Caused chronic branch Tracheitis mouse bronchial pathological change degree, respectively compared with model group, difference has the meaning of highly significant（P<0.01）；This Five groups of administration groups of invention can also very significantly mitigate SO₂Caused Chronic Bronchitis Mice Pulmonary lesions degree, with Model group compares, and difference is very significant（P<0.01）.Compared with the Chinese medicine group of certain commercially available treatment chronic bronchitis, Five groups of administration groups of the present invention also can significantly mitigate SO₂Caused Chronic Bronchitis Mice bronchus pathological change degree, SO can also significantly be mitigated₂Caused Chronic Bronchitis Mice Pulmonary lesions degree, both difference are respectively provided with conspicuousness Meaning（P<0.05）.Therefore, the pathological change of the Chinese medicine of certain more commercially available treatment chronic bronchitis of Chinese medicine composition of the invention Degree also has obvious advantage.

Influence result of the medicine of table 1 to chronic bronchitis model mouse bronchial, Pulmonary lesions

Remarks：Compared with model group, * * --- P<0.01, * --- P<0.05.

Note 1：+++ --- tracheal epithelium denaturation is serious, and the de- damage of cilium is thinning serious, and goblet cell is more, and is denatured serious；+ + --- tracheal epithelium denaturation weight, the de- damage of cilium is thinning heavy, and goblet cell is more, and is denatured weight；+ --- tracheal epithelium denaturation is lighter, The de- damage of cilium is thinning relatively light, and goblet cell is more, and is denatured lighter；0 --- it is normal.

Note 2：+++ --- inflammatory cell infiltration is serious, and alveolar denaturation is serious；++ --- inflammatory cell infiltration weight, alveolar become Property weight；+ --- inflammatory cell infiltration is lighter, and alveolar denaturation is lighter；0 --- it is normal.

Clinical observation is tested

Patient data

Patient 600, wherein, man 350, female 250 is diagnosed as chronic bronchitis, the age minimum 25 years old, the age Maximum 80 years old, the course of disease 3 year to 30 year in the majority with more than 60 years old person is in the majority with more than 10 years persons, according to M-F, age The method of ratio and course of disease balanced proportion is divided into six groups, a respectively control group and five treatment groups, does not have between six groups of patients There is otherness statistically.This six groups of patients once use the treatment methods such as Western medicine or Chinese medicine before this treatment is received, but It is that effect is not notable, easily recurrence, it is impossible to except root.

Diagnostic criteria

（1）Clinically to cough, cough up phlegm as cardinal symptom or with panting, fall ill continue 3 months every year, and continuous 2 years Or more；

（2）Fall ill every year less than 3 months, and have obvious objective determination foundation（Such as x-ray, determination of respiratory function）；

（3）Other hearts, lung disease can be excluded（Such as pulmonary tuberculosis, asthma, bronchiectasis, lung cancer, heart disease）.

Therapeutic scheme

Control group：Patient takes the Chinese medicine of certain commercially available treatment chronic bronchitis orally, and it is decoction, one after each meal, one Three times, each 50mL, one month is a course for the treatment of, continuously takes three courses for the treatment of；

Treatment group：Patient takes the embodiment of the present invention one orally to the Chinese medicine composition of embodiment five, is taken after meal after 1h, one Secondary, one week is a course for the treatment of, continuously takes three courses for the treatment of.

Daily follow-up once, is evaluated respectively before medication and after medication, after treatment finishes, continues follow-up 3 years, treatment Before, further consultation and fill in CRF during follow-up.

All subjects must not merge any other medicine for treating chronic bronchitis of use during experiment and can Clinical efficacy and the medicine of adverse reaction evaluation can be influenceed.

Observation index

First, observation cough, coughed up phlegm, panting etc., clinical manifestation improves situation, second, observation lung wheezing sound improvement situation, Third, laboratory blood gas analysis is observed, partial pressure of oxygen is recorded（PaO₂）, carbon dioxide partial pressure（PaCO₂）, oxygen saturation（SaO₂）And acid Soda balance（PH value）Four indexs.

The standard of curative effect evaluation

Cure：Cough, cough up phlegm, wheezing symptoms turn for the better by and large, the level before lung's wheezing sound recovery breaking-out, PaO₂> 95mmHg、PaCO₂<34mmHg、SaO₂>95%th, pH is normal；

It is effective：Cough, cough up phlegm, wheezing symptoms improvement more than sixty percent, lung's wheezing sound is clearly better, but does not recover to break out it Preceding level, PaO₂ 90-95mmHg、PaCO₂<40mmHg、SaO₂90-95%, pH are normal；

Take a turn for the better：Cough, cough up phlegm, wheezing symptoms improvement three has also taken a turn for the better into the above, lung's wheezing sound, PaO₂>85mmHg、 PaCO₂<45mmHg、SaO₂>85%th, pH is normal or relatively low；

It is invalid：Cough, cough up phlegm, wheezing symptoms without changing or take a turn for the better less than three one-tenth, lung's wheezing sound aggravates, PaO₂< 85mmHg、PaCO₂>45mmHg、SaO₂<85%th, pH is reduced.

Therapeutic effect

Six groups of clinical treatment outcomes collect as shown in table 2.

The clinical treatment outcome summary sheet of table 2

Clinical observation result

As can be seen from Table 2, five kinds of Chinese medicine compositions of the invention are respectively provided with good treatment to treatment chronic bronchitis Effect, clearly, cure rate is significantly raised for advantage, and improvement rate and inefficiency substantially reduce, and total effective rate 98%, dose is few, It is convenient to take, the pain of patient is significantly reduced, it is quick, short treating period, have no toxic side effect, treat both principal and secondary aspect of disease.

Model case

Case 1：Mr. Li, male, 30 years old, peasant because of illness of suffering from cold of drenching with rain, usually broke out after catching cold, and Symptoms are There are rale in cough, shortness of breath, abundant expectoration, the dizzy soreness of waist, lung；Think that oneself is young, does not draw attention, hereafter, every weather becomes Change, haze or will break out after suffering from cold；Antibiotic is taken during breaking-out to be treated, disease is eased after taking antibiotic, still, It can also recur, work and life are influenceed when serious.Take the Chinese medicine composition of the present invention, once in the morning and once at night, one after each meal； After taking three courses for the treatment of, cough, cough up phlegm and wheezing symptoms disappearance, breathing is smooth, and lung's wheezing sound recovers before acute attack Level, laboratory blood gas analysis reach the standard of healing, normal work and life, and the state of mind is good；Continue follow-up 1 year, not See recurrence.

Case 2：Yang, man, 53 years old, enterprise personnel, before 15 years, infect chill, burst high fever, cough, rhinorrhea, disease Feelings are serious, after infusion treatment, leave abundant expectoration, paroxysmal coughs up cough and wheezing symptoms, can last for hours sometimes, and it is tight to enter Night Watch Weight；Have hobby of smoking and drink concurrently, can not give up for the moment；In the winter time, smoking or when haze it is more serious；Take Chinese herbal medicine throughout the year Decoction, when being in a bad way, additional antibiotic carries out relief of symptoms, still, is all that can only take stopgap measures to effect a permanent cure, sends out repeatedly Make.Take the Chinese medicine composition of the present invention, once in the morning and once at night, one after each meal；After taking three courses for the treatment of, cough, cough up phlegm, disease of panting Shape turns for the better by and large, and breathing is smooth, and lung's wheezing sound recovers the level before breaking-out, and laboratory blood gas analysis reaches the mark of healing Standard, normal work and life, it is happy；Continue follow-up 2 years, no relapse.

Case 3：Field so-and-so, female, 75 years old, retired professor, suffer with chronic bronchitis 20 years, it is main because fatigue is suffered from cold illness Wanting symptom, cough frequency is high, and cycle length, breathing is very difficult, and breaking-out every time continues more than one hours for abundant expectoration, cough；Especially In the winter time, broken out after cloudy day or haze weather and suction irritative gas；In many ways seek medical advice, took a variety of herbal decoctions Or pill, course for the treatment of length, slowly effect, and can only take stopgap measures and can not effect a permanent cure, produce little effect.The Chinese medicine composition of the present invention is taken, sooner or later Respectively once, one after each meal；After taking three courses for the treatment of, cough, cough up phlegm, wheezing symptoms turn for the better by and large, smooth, the lung's wheezing sound of breathing Recover the level before breaking-out, laboratory blood gas analysis reaches the standard of healing, and happy, weather is fine；Continue with Visit 3 years, no relapse.

Therefore, the beneficial effect of Chinese medicine composition of the invention is：The present invention is in Chinese ephedra, rhizoma zingiberis, radix glycyrrhizae, balloonflower root, loquat Leaf, aster, tussilago, great burdock achene, lily, Radix Angelicae Sinensis, cassia twig, peppermint, the tuber of pinellia, the windproof, root bark of white mulberry, asarum, the fruit of Chinese magnoliavine, the root of herbaceous peony, This 28 taste Chinese herbal medicine of birthwort, the bighead atractylodes rhizome, radix scutellariae, the coptis, the capsule of weeping forsythia, Snakegourd Fruit, caulis bambusae in taenian, Folium Elaeagni, old caulis perllae and tip or stalactite is former Expect under scientific compatibility, focus depths of going directly, by the spleen of human body, stomach, lung, the heart, liver, courage, intestines and bladder progress system and entirely The conditioning in face, relieving cough and asthma, regulating qi-flowing for eliminating phlegm is reached, clearing heat and detoxicating, blood-nourishing holds back that cloudy, complement drives wind, clearing away the heart fire and tranquillizing, invigorating the spleen are reinforced the kidney The effect of, while also have the function that to strengthen body immunity, chronic bronchitis can be fundamentally cured, realizes sample With the purpose controlled；Its short treating period, quick, cure rate is high, and effective percentage efficacy stability, does not recur, had no toxic side effect, greatly up to 98% Alleviate patient's economy and psychological burden greatly.

The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention God any modification, equivalent substitution and improvements made etc., should be included in the scope of the protection with principle.

Claims (3)

1. A kind of 1. Chinese medicine composition for treating chronic bronchitis, it is characterised in that：It is made up of the raw material of following parts by weight：

   Chinese ephedra 8-12 parts, rhizoma zingiberis 8-12 parts, radix glycyrrhizae 8-12 parts, balloonflower root 8-12 parts, Pi are leaf 8-12 parts, aster 8-12 parts, coltsfoot Flower 8-12 parts, great burdock achene 8-12 parts, lily 8-12 parts, Radix Angelicae Sinensis 8-12 parts, cassia twig 8-12 parts, peppermint 8-12 parts, tuber of pinellia 8-12 parts, Windproof 8-12 parts, root bark of white mulberry 8-12 parts, asarum 8-12 parts, fruit of Chinese magnoliavine 8-12 parts, root of herbaceous peony 8-12 parts, birthwort 8-12 parts, the bighead atractylodes rhizome 8-12 parts, radix scutellariae 4-8 parts, coptis 4-8 parts, capsule of weeping forsythia 4-8 parts, Snakegourd Fruit 8-12 parts, caulis bambusae in taenian 4-8 parts, Folium Elaeagni 8-12 parts, old caulis perllae 8-12 parts, tip or stalactite 8-12 parts.
2. 2. the Chinese medicine composition for the treatment of chronic bronchitis according to claim 1, it is characterised in that：By following parts by weight Raw material be made：

   10 parts of Chinese ephedra, 10 parts of rhizoma zingiberis, 10 parts of radix glycyrrhizae, 10 parts of balloonflower root, Pi are 10 parts of leaf, 10 parts of aster, 10 parts of tussilago, great burdock achene 10 parts, 10 parts of lily, 10 parts of Radix Angelicae Sinensis, 10 parts of cassia twig, 10 parts of peppermint, 10 parts of the tuber of pinellia, windproof 10 parts, 10 parts of the root bark of white mulberry, asarum 10 Part, 10 parts of the fruit of Chinese magnoliavine, 10 parts of the root of herbaceous peony, 10 parts of birthwort, 10 parts of the bighead atractylodes rhizome, 6 parts of radix scutellariae, 6 parts of the coptis, 6 parts of the capsule of weeping forsythia, 10 parts of Snakegourd Fruit, 6 parts of caulis bambusae in taenian, 10 parts of Folium Elaeagni, 10 parts of old caulis perllae, 10 parts of tip or stalactite.
3. 3. the Chinese medicine composition for the treatment of chronic bronchitis according to claim 1 or 2, it is characterised in that：

   The formulation of the Chinese medicine composition is one kind in decoction, pill, granule, capsule or tablet.