CN108291207A - 神经前体细胞群体及其用途 - Google Patents

神经前体细胞群体及其用途 Download PDF

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Publication number
CN108291207A
CN108291207A CN201680071312.9A CN201680071312A CN108291207A CN 108291207 A CN108291207 A CN 108291207A CN 201680071312 A CN201680071312 A CN 201680071312A CN 108291207 A CN108291207 A CN 108291207A
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China
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cell
cells
neural precursor
enriched
neural
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CN201680071312.9A
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English (en)
Chinese (zh)
Inventor
科里·尼古拉斯
路易斯·富恩蒂尔巴
童卓卡
玛丽娜·伯施泰恩
索尼娅·克里克斯
斯图尔特·钱伯斯
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Neuron Therapy Co
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Neuron Therapy Co
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Publication of CN108291207A publication Critical patent/CN108291207A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
CN201680071312.9A 2015-10-08 2016-10-10 神经前体细胞群体及其用途 Pending CN108291207A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562239042P 2015-10-08 2015-10-08
US62/239,042 2015-10-08
PCT/US2016/056316 WO2017062971A1 (en) 2015-10-08 2016-10-10 Neural precursor cell populations and uses thereof

Publications (1)

Publication Number Publication Date
CN108291207A true CN108291207A (zh) 2018-07-17

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Family Applications (1)

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CN201680071312.9A Pending CN108291207A (zh) 2015-10-08 2016-10-10 神经前体细胞群体及其用途

Country Status (8)

Country Link
US (1) US20180369287A1 (enExample)
EP (1) EP3359647A1 (enExample)
JP (4) JP2018529389A (enExample)
CN (1) CN108291207A (enExample)
AU (2) AU2016335563B2 (enExample)
CA (1) CA3001316A1 (enExample)
HK (1) HK1258172A1 (enExample)
WO (1) WO2017062971A1 (enExample)

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CN113826564A (zh) * 2021-08-31 2021-12-24 南通大学 一种检测小鼠运动能力的方法
CN114736957A (zh) * 2022-04-15 2022-07-12 中国人民解放军空军军医大学 外泌体介导rna casc15干预阿尔茨海默症突触损失的应用
CN117092354A (zh) * 2023-10-18 2023-11-21 亿航(苏州)生物医药有限公司 一种用于识别脑源性细胞的细胞外囊泡的蛋白标志物

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JP2022043373A (ja) * 2018-12-28 2022-03-16 国立大学法人京都大学 大脳皮質細胞からのｌ１ｃａｍ陽性細胞の取得およびその細胞製剤としての使用
US12343359B2 (en) 2019-05-23 2025-07-01 Dignity Health Inhibitory interneuron treatment methods, uses and compositions for diabetes
WO2023004345A1 (en) * 2021-07-21 2023-01-26 University Of Washington Compositions and methods for enhancing cardiomyocyte transplant engraftment
KR102684884B1 (ko) * 2021-08-05 2024-07-15 성균관대학교산학협력단 신경줄기세포의 줄기세포능 증진을 위한 gng2의 용도
WO2025075929A1 (en) * 2023-10-02 2025-04-10 Neurona Therapeutics Inc. Methods of treating seizure activity

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113826564A (zh) * 2021-08-31 2021-12-24 南通大学 一种检测小鼠运动能力的方法
CN114736957A (zh) * 2022-04-15 2022-07-12 中国人民解放军空军军医大学 外泌体介导rna casc15干预阿尔茨海默症突触损失的应用
CN114736957B (zh) * 2022-04-15 2024-03-12 中国人民解放军空军军医大学 外泌体介导rna casc15干预阿尔茨海默症突触损失的应用
CN117092354A (zh) * 2023-10-18 2023-11-21 亿航(苏州)生物医药有限公司 一种用于识别脑源性细胞的细胞外囊泡的蛋白标志物
CN117092354B (zh) * 2023-10-18 2023-12-29 亿航(苏州)生物医药有限公司 一种用于识别脑源性细胞的细胞外囊泡的蛋白标志物

Also Published As

Publication number Publication date
EP3359647A1 (en) 2018-08-15
JP2020202865A (ja) 2020-12-24
AU2023200389B2 (en) 2025-09-25
JP7598655B2 (ja) 2024-12-12
AU2023200389A1 (en) 2023-02-23
JP2018529389A (ja) 2018-10-11
US20180369287A1 (en) 2018-12-27
JP2025022948A (ja) 2025-02-14
CA3001316A1 (en) 2017-04-13
JP2022169768A (ja) 2022-11-09
JP7138959B2 (ja) 2022-09-20
AU2016335563A1 (en) 2018-05-24
WO2017062971A1 (en) 2017-04-13
AU2016335563B2 (en) 2022-10-27
HK1258172A1 (zh) 2019-11-08

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