CN108261493A - A kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and preparation method thereof - Google Patents
A kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and preparation method thereof Download PDFInfo
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- CN108261493A CN108261493A CN201611267393.8A CN201611267393A CN108261493A CN 108261493 A CN108261493 A CN 108261493A CN 201611267393 A CN201611267393 A CN 201611267393A CN 108261493 A CN108261493 A CN 108261493A
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- cortex phellodendri
- rhizoma anemarrhenae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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Abstract
The invention discloses a kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and preparation method thereof, use traditional Chinese medicinal components for：Using Cortex Phellodendri, rhizoma anemarrhenae, the root of bidentate achyranthes, Radix Salviae Miltiorrhizae, rheum officinale, motherwort as main ingredient, it is subject to Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball made of auxiliary material, can be clearing heat and detoxicating before the treatment while row gland hyperplasia, the effect of purging intense heat eliminating dampness, promoting blood circulation, nourishing blood and tranquilization, cool blood detumescence；It treats the sick significant effect such as hyperplasia of prostate.
Description
Technical field
The present invention relates to the technical field of Chinese medicine, espespecially a kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and preparation method thereof.
Background technology
Hyperplasia of prostate (BPH), is once called as hypertrophy of the prostate, is one of older men common disease, is the one of prostate
Kind benign lesion.Its pathogenic factor is related with the dysequilibrium of estrogen with androgen in human body.Lesion is sticked originating from Posterior urethral
Glandular tissue, connective tissue and the smooth muscle tissue in middle period or lateral lobe under film form Combination spherical shape tubercle.With two lateral lobes and
Middle lobe hyperplasia is apparent, is charged into bladder or urethra, oppresses bladder neck or urethra, causes lower urinary tract obstruction.Hyperplasia of prostate
When causing obstruction, detrusor urinae of bladder thickens, and girder, cell and diverticulum occurs in mucous membrane.Long-term dysuria expands bladder height
, bladder wall thins, intravesical pressure increases, distal ureteral lose its flap valve effect, generate the vesicoureteric reflux age be
One of primary condition of hyperplasia of prostate morbidity.40 years old are a climacterics for the development of people, as.Plain Questions
It is described in the big opinion 〃 of YIN YANG classification of natural phenomena：" Nian Sishi, and half of YIN QI consumed, decline of vitality in daily life ".After illustrating 40 years old, each organizer of people
Official is starting to go down hill, and for example the interstitial components epithelial tissue that compares is more active in the prostata tissue of people, and prostate occurs
During hyperplasia, it is mainly shown as interstitial proliferation.Although people not yet thoroughly understand the hyperplasia of prostate cause of disease following measures are to subtracting
Hypopathia feelings and the generation for postponing the disease still have certain value.
At present, the method for traditional Chinese medicine is mostly the method taken using decocting, uses all to need to decoct every time and process, time-consuming to take
Power, using inconvenience.And water honey pill is suitable for and assimilates, and also eliminates peculiar peculiar smell stimulation when Chinese herbs decoction is taken, thus
On medication reaction, also it is easier to by big well-established.
Invention content
A kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball of the present invention and preparation method thereof can solve the deficiency of above-mentioned technology, use
Chinese Medicine Cortex Phellodendri, rhizoma anemarrhenae, the root of bidentate achyranthes, Radix Salviae Miltiorrhizae, rheum officinale, motherwort are major ingredient, are subject to auxiliary material through crushing, extracting, mediating pill, drying
Step prepares Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball, so as to fulfill treatment hyperplasia of prostate, the purpose of clearing heat and promoting diuresis.
To achieve these goals, technical solution of the invention is：A kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and its system
The main ingredient composition of Preparation Method：Cortex Phellodendri 11%~13%, rhizoma anemarrhenae 11%~13%, the root of bidentate achyranthes 12%~14%, Radix Salviae Miltiorrhizae 27%~29%, rheum officinale 6%~
8%th, motherwort 27%~29%.
Preparation process is as follows：
It crushes：Cortex Phellodendri, rhizoma anemarrhenae, the root of bidentate achyranthes, Radix Salviae Miltiorrhizae, rheum officinale, motherwort in main ingredient composition are cleaned respectively, dries, crush, crosses 60
Mesh sieves, and extracting screen underflow obtains mixed powder；
Extraction：Using supercritical extracting equipment device, mixed powder is put into supercritical CO2In the extraction kettle of extraction equipment, add
Enter supercritical CO2For extractant, 30 DEG C~50 DEG C, extracting pressure 15Mpa~30Mpa of extraction temperature, extraction time is
5h~6h enters extract liquor in separating still to heat up, decompression detaches, caking product in collection separating still, then crushes
100 mesh sieve, and obtain extraction powder；
Mediate pill：Will extraction powder 50% be placed in kneader, add supplementary product starch 47%~49%, be slowly added to adhesive 1%~
3% refining honey, uniform stirring kneading are made wet medicine and stick together, and wet medicine is sticked together the wet ball for being placed in and every 5g being made in pellet processing machine；
It is dry：Will wet ball be placed in it is dry in belt microwave drying machine, will dried pill be placed in irradiation 3 under ultraviolet light~
It is packed in time after 5min, as finished product.
A kind of dosage of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball of the present invention is：If the patient with chronic pelvic inflammatory disease, every time 1
Ball, in two times early supper clothes.
Cortex Phellodendri of the present invention has clearing heat and detoxicating, purging intense heat eliminating dampness；Cure mainly acute bacillary dysentery, chordapsus, urgency
The inflammation such as property icteric hepatitis, urinary system infection contamination；Burning hot wound, tympanitis, acute conjunctivitis effect are controlled in external application；Have with rhizoma anemarrhenae
Clearing heat-fire, fluid dryness；For fever caused by exogenous pathogenic factors, hyperpyrexia polydipsia, lung-heat type cough, osteopyrexia and fever, Heat Diabetes, dry constipation of intestines
Effect；The root of bidentate achyranthes has dispelling stasis of blood and stimulating the menstrual flow, filling liver kidney, strengthening the bones and muscles, inducing diuresis for treating strangurtia；Radix Salviae Miltiorrhizae has promoting blood circulation, nourishing blood and tranquilization, and cool blood disappears
The effect of swollen；Hemostasis head, chest, the side of body, abdomen pain are cured mainly, is gathered, irregular menstruation, dysmenorrhoea Amenorrhea, postpartum stasis of blood, joint numbness
Bitterly, it beats the stasis of blood swell, warm disease is vexed, palpitation due to deficiency of blood, sore swollen toxin, red rash mange；Rheum officinale, which has, to purge heat logical intestines, removing pattogenic heat from the blood and toxic material from the body, by
The effect of stasis of blood promoting menstruation；Motherwort has promoting blood circulation, and dissolving stasis, menstruation regulating, disappear water；Control irregular menstruation, threatened abortion difficult labour, placenta retension, postpartum
The effect of bruise, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria rush down blood, carbuncle swells sore；With Cortex Phellodendri, rhizoma anemarrhenae, the root of bidentate achyranthes, Radix Salviae Miltiorrhizae, rheum officinale, benefit
Brittle Falsepimpernel Herb is main ingredient, is subject to Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball made of auxiliary material, can be with heat-clearing solution before the treatment while row gland hyperplasia
The effect of poison, purging intense heat eliminating dampness, promoting blood circulation, nourishing blood and tranquilization, cool blood detumescence；It treats the sick significant effect such as hyperplasia of prostate.
Specific embodiment
Embodiment 1
(1) main ingredient composition：Cortex Phellodendri 11%, rhizoma anemarrhenae 11%, the root of bidentate achyranthes 12%, Radix Salviae Miltiorrhizae 29%, rheum officinale 8%, motherwort 29%.
(2) preparation process is as follows：
1）It crushes：Cortex Phellodendri, rhizoma anemarrhenae, the root of bidentate achyranthes, Radix Salviae Miltiorrhizae, rheum officinale, motherwort in main ingredient composition are cleaned respectively, dries, crush, mistake
60 mesh sieve, and extracting screen underflow obtains mixed powder；
2）Extraction：Using supercritical extracting equipment device, mixed powder is put into supercritical CO2In the extraction kettle of extraction equipment, add
Enter supercritical CO2For extractant, 30 DEG C~50 DEG C, extracting pressure 15Mpa~30Mpa of extraction temperature, extraction time is
5h~6h enters extract liquor in separating still to heat up, decompression detaches, caking product in collection separating still, then crushes
100 mesh sieve, and obtain extraction powder；
3）Mediate pill：Extraction powder 50% is placed in kneader, supplementary product starch 47%~49% is added, is slowly added to adhesive 1%
~3% refining honey, uniform stirring kneading are made wet medicine and stick together, and wet medicine is sticked together the wet ball for being placed in and every 5g being made in pellet processing machine；
4）It is dry：Will wet ball be placed in it is dry in belt microwave drying machine, will dried pill be placed in irradiation 3 under ultraviolet light~
It is packed in time after 5min, as finished product.
Embodiment 2
(1) main ingredient composition：Cortex Phellodendri 12%, rhizoma anemarrhenae 12%, the root of bidentate achyranthes 13%, Radix Salviae Miltiorrhizae 28%, rheum officinale 7%, motherwort 28%.
(2) it is as follows for step：
1）It crushes：Cortex Phellodendri, rhizoma anemarrhenae, the root of bidentate achyranthes, Radix Salviae Miltiorrhizae, rheum officinale, motherwort in main ingredient composition are cleaned respectively, dries, crush, mistake
60 mesh sieve, and extracting screen underflow obtains mixed powder；
2）Extraction：Using supercritical extracting equipment device, mixed powder is put into supercritical CO2In the extraction kettle of extraction equipment, add
Enter supercritical CO2For extractant, 30 DEG C~50 DEG C, extracting pressure 15Mpa~30Mpa of extraction temperature, extraction time is
5h~6h enters extract liquor in separating still to heat up, decompression detaches, caking product in collection separating still, then crushes
100 mesh sieve, and obtain extraction powder；
3）Mediate pill：Extraction powder 50% is placed in kneader, supplementary product starch 47%~49% is added, is slowly added to adhesive 1%
~3% refining honey, uniform stirring kneading are made wet medicine and stick together, and wet medicine is sticked together the wet ball for being placed in and every 5g being made in pellet processing machine；
4）It is dry：Will wet ball be placed in it is dry in belt microwave drying machine, will dried pill be placed in irradiation 3 under ultraviolet light~
It is packed in time after 5min, as finished product.
Embodiment 3
(1) main ingredient composition：Cortex Phellodendri 13%, rhizoma anemarrhenae 13%, the root of bidentate achyranthes 14%, Radix Salviae Miltiorrhizae 27%, rheum officinale 6%, motherwort 27%.
(2) it is as follows for step：
1）It crushes：Cortex Phellodendri, rhizoma anemarrhenae, the root of bidentate achyranthes, Radix Salviae Miltiorrhizae, rheum officinale, motherwort removal of impurities, drying in main ingredient composition are crushed, cross 60
Mesh sieves, and extracting screen underflow obtains mixed powder；
2）Extraction：Using supercritical extracting equipment device, mixed powder is put into supercritical CO2In the extraction kettle of extraction equipment, add
Enter supercritical CO2For extractant, 30 DEG C~50 DEG C, extracting pressure 15Mpa~30Mpa of extraction temperature, extraction time is
5h~6h enters extract liquor in separating still to heat up, decompression detaches, caking product in collection separating still, then crushes
100 mesh sieve, and obtain extraction powder；
3）Mediate pill：Extraction powder 50% is placed in kneader, supplementary product starch 47%~49% is added, is slowly added to adhesive 1%
~3% refining honey, uniform stirring kneading are made wet medicine and stick together, and wet medicine is sticked together the wet ball for being placed in and every 5g being made in pellet processing machine；
4）It is dry：Will wet ball be placed in it is dry in belt microwave drying machine, will dried pill be placed in irradiation 3 under ultraviolet light~
It is packed in time after 5min, as finished product.
The above, embodiment is only that the preferred embodiment of the present invention is described, not to the present invention's
Range is defined, and under the premise of the spirit of the technology of the present invention is not departed from, this field engineers and technicians are to the skill of the present invention
The various modifications and improvement that art scheme is made should all be fallen into the protection domain that claims of the present invention determines.
Claims (1)
1. a kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and preparation method thereof, it is characterized in that：Main ingredient composition is：Cortex Phellodendri 11%~13% is known
Mother 11%~13%, the root of bidentate achyranthes 12%~14%, Radix Salviae Miltiorrhizae 27%~29%, rheum officinale 6%~8%, motherwort 27%~29%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611267393.8A CN108261493A (en) | 2016-12-31 | 2016-12-31 | A kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611267393.8A CN108261493A (en) | 2016-12-31 | 2016-12-31 | A kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108261493A true CN108261493A (en) | 2018-07-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611267393.8A Pending CN108261493A (en) | 2016-12-31 | 2016-12-31 | A kind of Cortex Phellodendri rhizoma anemarrhenae clearing heat and promoting diuresis ball and preparation method thereof |
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| CN (1) | CN108261493A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109157579A (en) * | 2018-11-26 | 2019-01-08 | 西安百世惠众生物工程有限公司 | It is a kind of to treat pure Chinese medicinal preparation of prostatic disorders and preparation method thereof |
-
2016
- 2016-12-31 CN CN201611267393.8A patent/CN108261493A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109157579A (en) * | 2018-11-26 | 2019-01-08 | 西安百世惠众生物工程有限公司 | It is a kind of to treat pure Chinese medicinal preparation of prostatic disorders and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180710 |
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| WD01 | Invention patent application deemed withdrawn after publication |